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  • An assimilation analysis of psychotherapy : responsibility for being there / Lara Honos-Webb ... [et al.] -- Exploring psychotherapy with discourse analysis : chipping away at the mortar / Anna Madill -- The grounded theory method : application of a variant of its procedure of constant comparative analysis to psychotherapy research / David L. Rennie -- Phenomenological analysis : impression formation during a clinical assessment interview / Scott D. Churchill -- Diagnostic discourse in patient-staff interactions : a conversation analysis clarified by participant interviews / Jessie Goicoechea -- Honor and respect : feminist collaborative research with sexually abused women / Susan L. Morrow -- An empirical, phenomenological study : being joyful / Brent Robbins -- Conceptual encounter : the experience of anger / Joseph de Rivera -- Emergence of the dialogal approach : forgiving another / Steen Halling, Michael Leifer, and Jan O. Rowe -- A thematic analysis of written accounts : thinking about thought / Howard R. Pollio and Michael J. Ursiak -- Intuitive inquiry : an exploration of embodiment among contemporary female mystics / Vipassana Esbjörn-Hargens and Rosemarie Anderson -- An application of experiential method in psychology : what is it like to be a stranger in a foreign land / Arne Collen -- Focus groups and related rapid assessment methods : identifying psychoeducational HIV/AIDS interventions in Botswana / Lisa Levers.
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    Part 1. Background to the Quality and Outcomes Framework -- 1. Introduction: development, impact and implications / Steve Gillam and A. Niroshan Siriwardena -- 2. Where did the Quality and Outcomes Framework come from? / Martin Roland -- 3. Developing indicators and the concept of QOF ability / Stephen Campbell and Helen Lester -- Part II. Impact of the Quality and Outcomes Framework -- 4. Learning from the QOF: a review of existing research / Nicholas Steel and Sara Willems -- 5. The public health impact / Anna Dixon, Artak Khachatryan and Tammy Boyce -- 6. 'Smoke and mirrors'? Informatics opportunities and challenges / Maria Kordowicz and Mark Ashworth -- 7. The impact of the QOF on practice organisation and service delivery / Kath Checkland and Stephen Harrison -- Part III. Practical aspects of the Quality and Outcomes Framework -- 8. Getting the most out of the QOF / Chantal Simon and Anna Morton -- 9. Does the patient always benefit? / Patricia Wilkie -- Part IV. Reflections on pay-for-performance and the Quality and Outcomes Framework -- 10. Pay-for-performance schemes in primary care: what have we learnt? / Stephen Peckham and Andrew Wallace -- 11. An international perspective on the basis of pay-for-performance / Barbara Starfield and Dee Mangin -- 12. The Quality and Outcomes Framework: triumph of evidence or tragedy for personal care? / Steve Gillam and A. Niroshan Siriwardena.
  • pt. 1. Quality assurance of chemometric methods and pathology : selected topics -- pt. 2. Quality assurance aspects of newly emerging methods in pathology and laboratory medicine -- pt. 3. Accreditation, standards, and education : their role in maintaining quality.
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    v. 1. A compendium of guidelines and related materials -- v. 2. Good manufacturing practices and inspection.
  • 1 Challenges and Opportunities for Biotech Quality by Design -- 2 Lessons Learned From Monoclonal Antibody Applications to the Office of Biotechnology Products Quality by Design Pilot Program -- 3 Definitions and Scope of Key Elements of QbD -- 4 An Overview of Quality by Design for Drug Product -- 5 Development of Drug Product Formulations: Molecular Design and Early Candidates Screening -- 6 Approaches for Early Developability Assessment of Proteins to Guide Quality by Design of Liquid Formulations -- 7 Application of QbD Principles to Late-stage Formulation Development for Biological Liquid Products -- 8 Application of QbD Principles for Lyophilized Formulation Development -- 9 Drug Substance Frozen Storage and Thawing -- 10 Quality by Design as Applied to Drug Substance Formulation using Ultrafiltration and Diafiltration -- 11 A QbD Approach in the Development and Scale-up of Mixing Processes -- 12 Application of QbD Elements in the Development and Scale-up of a Commercial Filtration Process -- 13 Application of QbD Elements in the Development and Scale-up of Commercial Filling Process -- 14 Lyophilization Process Design and Development Using QbD Principles -- 15 Visible and Subvisible Protein Particle Inspection Within a QbD-based Strategy -- 16 Quality by Design for Distribution of Environmentally Sensitive Pharmaceutical Products -- 17 Quality by Design for Primary Container Components -- 18 Devices and Combination Products for Biopharmaceuticals -- 19 Applicability of QbD for Vaccine Drug Product Development -- 20 Automation and High Throughput Technologies in Biopharmaceutical Drug Product Development with QbD Approaches -- 21 Critical Quality Attributes, Specifications, and Control Strategy -- 22 Multivariate Analysis for Process Understanding, Monitoring, Control and Optimization in Lyophilization Processes -- 23 Using Mathematical Modeling and Prior Knowledge for QbD in Freeze-drying Processes -- 24 Application of Multivariate Statistical Process Monitoring to Lyophilization Process -- 25 Application of PAT in Real-time Monitoring and Controlling of Lyophilization Process -- 26 Product Homogeneity Assessment during Validation of Biopharmaceutical Drug Product Manufacturing Processes -- 27 Application of Quality by Design Principles to the Drug Product Technology Transfer Process -- 28 Regulatory Considerations For Implementation of the QbD Paradigm for Biologics: Laying the Foundation for Product and Process Lifecycle Management.
  • Improving quality and harmonization of standards in clinical genetic services in Europe: the EuroGentest Network of Excellence -- The CanGeneTest Pan-Canadian Research Consortium on genetic laboratory services -- Regulating genetic testing: the relevance of appropriate definitions -- Genetic diseases as rare diseases: a European policy view -- European regulatory issues related to quality in provision of genetic service -- The European IVD directive and genetic testing -- Quality issues in genetics services in the United Kingdom -- The primary care perspective of quality in clinical genetics service, United Kingdom as an example -- Regulation of genetic testing/service in Canada -- Quality issues in clinical genetic services in Australia -- Clinical genetic teesting and services, the US perspective -- US oversight and regulation of genetic testing -- Regulatory issues in clinical and laboratory genetics in developing countries: examples from Latin America -- Assuring quality when establishing medical genetic services in middle- and low-income nations -- Clinical validity and utility of genetic testing in heritable disorders -- Clinical validity and utility of genetic testing in common multifactorial diseases -- The quality of genetic screening: an integral approach -- The use of prinicples in allocating scarce health care resources for genetic tests -- Outcome measures in clinical genetics services -- Direct to consumer testing -- Competency based core curriculum for training specialists in clinical genetics -- Ensuring education and quality in the practice of health professionals (non-medical) working in genetic services -- Quality issues in clinical genetic services: ethical aspects -- Democratic expert influence through bioethical advisory committees? The case of PGD legislation in Sweden -- Quality issues in clinical genetic services; regulatory issues and international conventions -- IPR issues and high quality genetic testing -- Quality issues in the evaluation and regulation of genetic testing services: a public health approach -- Quality management systems and accreditation -- External quality assessment in molecular genetic testing -- Quality issues in molecular genetic testing -- Quality issues in molecular genetic testing -- Quality in cytogenetics -- Fluorescence in situ hybridization (FISH), quality issues in molecular cytogenetics -- Quality issues in biochemical genetic testing -- Emerging technologies, need for quality assessment -- Genetic counselling in rare diseases -- Genetic counselling for late-onset disorders -- Genetic counselling for common diseases, cancer susceptibility as paradigm -- Genetic counselling in disorders of low penetrance -- Patient perspectives on genetic testing -- Index.
  • The Difficulty of Assessing Quality or Quality-of-Life -- The Role of Language in Assessing Quality or Quality-of-Life -- What Role Do Cognitive Processes Play in Assessing Quality or Quality-of-Life? -- The Role of Objective or Subjective Indicators -- The Role of Signs or Symptoms -- Summary Measurement: The Role of Categories or Domains -- Symptoms and HRQOL Assessment -- Health Status and HRQOL Assessment -- Functional Status and HRQOL -- Neurocognition and HRQOL Assessment -- Well-Being as an Indicator of Quality or Quality-of-Life -- Summary and Future Directions.
  • In the last decades, major advances have been made in assisted reproductive technologies (ART) and the public demand for these procedures has increased globally. All ART clinics, from those just starting out to the well established, must employ the latest equipment and implement the best practices, while ensuring that their resources are effectively engaged to optimize patient outcomes. This is a tenet of the fiduciary role of physicians and it is increasingly recognized as a quantifiable goal regulated by formal certifications and accreditations. Quality management protocols such as those proposed by the International Organization for Standardization (ISO) are being rapidly adopted as standards of measure. Quality Management in ART Clinics: A Practical Guide provides easily adoptable ways to implement and improve formalized quality management systems. Essential to any clinic to achieve best practices and maintenance of formal regulatory certifications, this book brings together the know-how of experienced opinion leaders operating in key areas worldwide. The book offers an overview of primary regulations in the ART field, with attention to quality management demands, and links specific requirements to practical steps for implementation. Filled with process and procedure examples, flow diagrams and administrative form templates, this book is the first of its kind, gathering the necessary elements for optimizing practice, management, and quality assurance.
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  • Key methodological issues -- Distress/protection vulnerability model of quality of life impairment syndrome -- Role of dopamine in pleasure, reward and subjective responses to drugs -- Neuroendocrine functions,mood and quality of life -- In the mind of the beholder neuronal mediators for the effect of emotional experience on quality of life -- Cross-cultural quality of life research in mental health -- Measuring the value of health-related quality of life -- Comparison of instruments for measuring the quality of life impairment syndrome in severe mental disorders -- Integrative bottom-up approach to HRQQL measurement -- Quality of life impairment syndrome in severe mental disorders -- Health related quality of life in subjects at risk for a first episode of psychosis -- Quality of life impairment syndrome in schizophrenia -- Insight and quality of life in schizophrenia spectrum disorders -- Quality of life and major depression -- Quality of life impairment in bipolar disorder -- Quality of life impairment in anxiety disorders -- Quality of life in obsessive-compulsive disorder -- Treatment and rehabilitation issues -- Antipsychotic medications, schizophrenia and the issue of quality of life -- Quality of life outcomes of ECT -- Quality of life in mental health services -- Subjective quality of life in relation to psychiatric rehabilitation and daily life -- Cost-utility analysis.
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    Introduction -- Principles of measurement scales -- Developing a questionnaire -- Scores and measurements : validity, reliability, sensitivity -- Multi-item scales -- Factor analysis and structural equation modelling -- Item response theory and differential item functioning -- Item banks, item listing and computer-adaptive tests -- Choosing and scoring questionnaires -- Clinical trials -- Sample sizes -- Cross-sectional analysis -- Exploring longitudinal data -- Modelling longitudinal data -- Missing data -- Practical and reporting issues -- Quality-adjusted survival -- Clinical interpretation -- Meta-analysis.
  • An integrated approach to improving health and health care in rural communities -- Quality improvement activities in rural areas -- Human resources -- Finance -- Rural health care in the digital age.
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    Chapter 1. Introduction - The Evolution of Our Understanding of the Immune System -- Chapter 2. Molecular Immunology -- Chapter 3. The Problem - Understanding How Molecules Direct the Behavior of Cells Comprising the Immune System -- Chapter 4. The Quantal Theory of Immunity -- Chapter 5. The Variability of Cell Cycle Progression and the Competence and Progression Phases of the Cell Cycle -- Chapter 6. The Quantal Nature of IL-2-Promoted T Cell Cycle Progression -- Chapter 7. The Molecular Basis for Quantal IL-2/IL-2R Signaling of Cell Cycle Progression - The IL-2/Receptor Interaction -- Chapter 8. The Molecular Basis for Quantal IL-2/IL-2R Signaling of Cell Cycle Progression - IL-2 and IL-2 Receptor Metabolism -- Chapter 9. The Molecular Basis for Quantal IL-2/IL-2R Signaling of Cell Cycle Progression - IL-2 Receptor Signaling via the Jak/Stat Pathway -- Chapter 10. The Molecular Basis for Quantal IL-2/IL-2R Signaling of Cell Cycle Progression - IL-2 Receptor Signaling via Phosphorylation of IL-2R β Chain Y338 -- Chapter 11. The T Cell Antigen Receptor Complex and the Quantal Regulation of the IL-2 and IL-2R Genes -- Chapter 12. Digital Signaling via the T Cell Antigen Receptor Complex -- Chapter 13. Negative Feedback Regulation of T Cell Antigen Receptor Complex Signaling - Attenuation of IL-2 Gene Expression -- Chapter 14. The Paradox of the IL-2 (-/-) Mouse -- Chapter 15. The Scurfy Mouse -- Chapter 16. Lymphopenia, Autoimmunity and the Regulatory T Cell (Treg) -- Chapter 17. Treg-mediated "Active Suppression" of T Cell Proliferation -- Chapter 18. FOXP3, A Better ID-Tag for Tregs? -- Chapter 19. Mice Versus Men -- Chapter 20. Active Versus Passive Suppression and IL-2 Metabolism -- Chapter 21. FOXP3 Restricts But Does Not Suppress IL-2 Production -- Chapter 22. Both the TCR and IL-2 Regulate Foxp3 Expression -- Chapter 23. The Effects of FOXP3 Expression -- Chapter 24. Role of IL-2 in the Generation of Immune Responses In Vivo -- Chapter 25. The Role of the IL-2r Chains in IL-2 Signaling, Consumption and Suppression of T Cell Proliferation -- Chapter 26. T Cell Tissue-specific Autoimmunity -- Chapter 27. Type 1 Diabetes Mellitus (TIDM), a Prototypic Genetic Autoimmune Disease with a Tie to IL-2 -- Chapter 28. The Pathogenesis of Leukemia - Loss of Normal Quantal Growth Control.
  • "Although traditionally a qualitative technique, MRI can be used to gather quantitative information on the structure and function of the human body. While historically applied to neurophysiology, MRI is now routinely being used to explore other organs and structures, especially the heart and skeleton. This volume reviews various MRI techniques for obtaining quantitative and physiological information of the human body. It compares and contrasts several different applications of MRI in quantitative research and on various body parts/structures, including data acquisition, processing, and analysis/interpretation. The book also explores new and emerging techniques and modeling"--Provided by publisher.
  • Overview of quantitative drug design -- Noncovalent interactions in biological systems -- Preparation of 3D structures of molecules for 3D QSAR -- Calculating physical properties of molecules -- Biological data -- Form of equations that relate potency and physical properties -- Statistical basis of regression and partial least-squares analysis -- Strategy for the statistical evaluation of a data set of related molecules -- Detailed examples of QSAR calculations on erythromycin esters -- Case studies -- Methods to approach other structure-activity problems.
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    Statistical methodology and stochastic modeling -- Proteomics and genomics -- Survival modeling and analysis -- Mathematical models for diseases -- Computing and visualization.
  • Rationale for Quantitative MRI of the Human Spinal Cord and Clinical Applications -- Inflammatory Demyelinating Diseases -- Traumatic Spinal Cord Injury: Acute Spinal Cord Injury and Prognosis -- Traumatic Spinal Cord Injury: Chronic Spinal Cord Injury and Recovery -- Array Coils -- Bo Inhomogeneity and Shimming -- Susceptibility Artifacts -- Ultra-High Field Spinal Cord Imaging -- Diffusion-Weighted Imaging of the Spinal Cord -- Q-Space Imaging -- Advanced Methods to Study White Matter Microstructure -- Magnetization Transfer -- T₂ Relaxation -- Atrophy -- Spinal Cord fMRI -- Physiological Noise Modeling and Analysis for Spinal Cord fMRI -- Mapping the Vasculature of the Spinal Cord --Single Voxel MR Spectroscopy in the Spinal Cord: Technical Challenges and Clinical Applications -- Annex: Anatomy of the Spinal Cord.
  • Neural anatomy -- Passive membranes -- Active membranes -- Propagation -- Neural branches -- Synapses -- Networks of neurons -- Extracellular recording and stimulation -- The neural code -- Applications.
  • 1. Fluorogenic derivatization followed by HPLC quantification and final identification of proteins by HPLC-tandem mass spectrometry (FD-LC-MS/MS) method / Akiyo Koshiyama, Tomoko Ichibangase, and Kazuhiro Imai -- 2. Two-dimensional difference gel electrophoresis / Viola Ruddat -- 3. Mass spectrometry utilizing isotope-coded affinity tag reagents / Naoyuki Yamada -- 4. Proteomic analyses of post-translational modifications / Wei-Chi Ku and Yasushi Ishihama -- 5. Cardiovascular proteomic analysis / Toru Suzuki and Ryozo Nagai -- 6. The proteome in neurodegenerative diseases / Teruyuki Tsuji, Masahiro Aoki, and Shun Shimohama -- 7. Liver disease-related proteomics / Hirofumi Uto, Yoichiro Takami, Shuji Kanmura, and Hirohito Tsubouchi -- 8. Respiratory disease-related proteome / Masahiro Seike and Akihiko Gemma -- 9. Renal disease-related proteome / Shinya Kaname and Tadashi Yamamoto -- 10. Aging-related proteome / Tosifusa Toda -- 11. Phosphoproteomics of tumor cell lines / Hisafumi Okabe -- 12. HCV infection and mitochondria proteomics / Kyoji Moriya, Takeya Tsutsumi, Hideyuki Miyoshi, and Kazuhiko Koike -- 13. Identification of biomarkers of infectious disease using surface-enhanced laser desorption/ionisation mass spectrometry / Shea Hamilton and Paul R. Langford -- 14. Quantitative proteomic analysis of HIV infection / Li Juan Fu and Sam F.Y. Li.
  • Acrylamide: a cysteine alkylating reagent for quantitative proteomics / Illarion V. Turko and Salvatore Sechi -- Using stable isotope tagging and mass spectrometry to characterize protein complexes and to detect changes in their composition / Jeffrey A. Ranish, Marjorie Brand, and Ruedi Aebersold -- Stable isotope labeling by amino acids in cell culture for quantitative proteomics / Shao-En Ong and Matthias Mann -- Quantitative proteomics of mouse brain and specific protein-interaction studies using stable isotope labeling / Toshitaka Sato, Yasushi Ishihama, and Yoshiya Oda -- The absolute quantification strategy: application to phosphorylation profiling of human separase serine 1126 / Scott A. Gerber ... [et al.] -- Quantification of proteins and metabolites by mass spectrometry without isotopic labeling / Sushmita Mimi Roy and Christopher H. Becker -- The use of a quantitative cysteinyl-peptide enrichment technology for high-throughput quantitative proteomics / Tao Liu ... [et al.] -- An isotope coding strategy for proteomics involving both amine and carboxyl group labeling / Fred E. Regnier -- Proteolytic labeling with ¹⁸O for comparative proteomics studies: preparation of ¹⁸O-labeled peptides and the ¹⁸O/¹⁶O peptide mixture / Catherine Fenselau and Xudong Yao -- Tandem mass spectrometry in the detection of inborn errors of metabolism for newborn screening / František Tureček, C. Ronald Scott, and Michael H. Gelb -- Absolute quantification of specific proteins in complex mixtures using visible isotope-coded affinity tags / Yu Lu ... [et al.] -- Computational analysis of quantitative proteomics data using stable isotope labeling / Michael J. MacCoss and Christine C. Wu -- Quantitative proteomic analysis of mammalian organisms using metabolically labeled tissues / Christine C. Wu, and Michael J. MacCoss -- Quantitative proteomic analysis of phosphotyrosine-mediated cellular signaling networks / Yi Zhang, Alejandro Wolf-Yadlin, and Forest M. White.
  • Due to parallel advances in signal processing and computer hardware in the last 15 years, quantitative ultrasound techniques have reached maturity, allowing for the construction of quantitative maps or images of soft tissues. This book will focus on 5 modern research topics related to quantitative ultrasound of soft tissues: - Spectral-based methods for tissue characterization, tissue typing, cancer detection, etc.; - Envelope statistics analysis as a means of quantifying and imaging tissue properties; - Ultrasound elastography for quantifying elastic properties of tissues (several clinical ultrasound scanners now display elastography images); - Scanning acoustic microscopy for forming images of mechanical properties of soft tissues with micron resolution (desktop size scanners are now available); and - Ultrasound computer tomography for breast cancer imaging (new ultrasound tomography systems have been developed and are currently under evaluation clinically).
  • Immunofluorescent labeling of proteins in cultured cells with quantum dot secondary antibody conjugates / Richard L. Ornberg and Hongjian Liu -- Immunohistochemical detection with quantum dots / Rizwan S. Akhtar ... [et al.] -- Quantum dots for multicolor clinical pathology and multispectral imaging / Johbu Itoh and Robert Yoshiyuki Osamura -- Light and electron microscopic localization of multiple proteins using quantum dots / Thomas J. Deerinck ... [et al.] -- Human metaphase chromosome fluorescence in situ hybridization using quantum dot conjugates / Joan H.M. Knoll -- Biotin-ligand complexes with streptavidin quantum dots for in vivo cell-labeling of membrane receptors / Diane S. Lidke ... [et al.] -- Single quantum dot tracking of membrane receptors / Cødric Bouzigues ... [et al.] -- Optical monitoring of single cells using quantum dots / Jyoti K. Jaiswal and Sanford M. Simon -- Peptide-mediated intracellular delivery of quantum dots / B. Christoffer Lagerholm -- High-content analysis in multiple cell lines using quantum dots / Paul G. Wylie -- Measuring cell motility using quantum dot probes / Weiwei Gu ... [et al.] -- Quantum dots for in vivo molecular and cellular imaging / Xiaohu Gao, Leland W.K. Chung, and Shuming Nie -- Sentinel lymph node mapping with type II quantum dots / John V. Frangioni ... [et al.] -- Macrophage-mediated colocalization of quantum dots in experimental glioma / Osman Muhammad, Alexandra Popescu, and Steven A. Toms -- Applications of quantum dots to multicolor flow cytometry / Pratip K. Chattopadhyay and Mario Roederer -- Quantum dots in flow cytometry / Barnaby Abrams and Tim Dubrovsky -- Luminescent biocompatible quantum dots: a tool for immunosorbent assay design / Ellen R. Goldman ... [et al.] -- Fluorescence-based analysis of cellular protein lysate arrays using quantum dots / David H. Geho ... [et al.] -- Application of quantum dots to multicolor microarray experiments: four-color genotyping / George Karlin-Neumann ... [et al.].
  • Front Matter -- Colour Plates -- Factors of High-Risk Pregnancy. Overview of High-Risk Pregnancy / John T Queenan, Catherine Y Spong, Charles J Lockwood -- Maternal Nutrition / Edward R Newton -- Alcohol and Substance Abuse / William F Rayburn -- Environmental Agents and Reproductive Risk / Laura Goetzl -- Genetics. Genetic Screening for Mendelian Disorders / Deborah A Driscoll -- Screening for Congenital Heart Disease / Lynn L Simpson -- First- and Second-Trimester Screening for Fetal Aneuploidy and Neural Tube Defects / Julia Unterscheider, Fergal D Malone -- Monitoring: Biochemical and Biophysical. Sonographic Dating and Standard Fetal Biometry / Eliza Berkley, Alfred Abuhamad -- Fetal Lung Maturity / Alessandro Ghidini, Sarah H Poggi -- Antepartum Fetal Monitoring / Brian L Shaffer, Julian T Parer -- Interpreting Intrapartum Fetal Heart Tracings / Michael Nageotte -- Maternal Disease. Sickle Cell Anemia / Scott Roberts -- Anemia / Alessandro Ghidini -- Thrombocytopenia / Robert M Silver -- Inherited and Acquired Thrombophilias / Michael J Paidas -- Thromboembolic Disorders / Christian M Pettker, Charles J Lockwood -- Cardiac Disease / Stephanie R Martin, Alexandria J Hill, Michael R Foley -- Renal Disease / David C Jones -- Pregnancy in Transplant Patients / James R Scott -- Gestational Diabetes Mellitus / Deborah L Conway -- Diabetes Mellitus / George Saade -- Hypothyroidism and Hyperthyroidism / Brian Casey -- Asthma / Michael Schatz -- Epilepsy / Autumn M Klein, Page B Pennell -- Chronic Hypertension / Heather A Bankowski, Dinesh M Shah -- Systemic Lupus Erythematosus / Christina S Han, Edmund F Funai -- Perinatal Infections / Jeanne S Sheffield -- Malaria / Richard M K Adanu -- Group B Streptococcal Infection / Ronald S Gibbs -- Hepatitis / Patrick Duff -- HIV Infection / Howard L Minkoff -- Pregnancy in Women with Physical Disabilities / Caroline C Signore -- Obstetric Complications. Recurrent Spontaneous Abortion / Charles J Lockwood -- Cervical Insufficiency / John Owen -- Gestational Hypertension, Preeclampsia, and Eclampsia / Labib M Ghulmiyyah, Baha M Sibai -- Postpartum Hemorrhage / Michael A Belfort -- Emergency Care / Garrett K Lam, Michael R Foley -- Rh and Other Blood Group Alloimmunizations / Kenneth J Moise -- Multiple Gestations / Karin E Fuchs, Mary E D'Alton -- Polyhydramnios and Oligohydramnios / Ron Beloosesky, Michael G Ross -- Prevention of Preterm Birth / Paul J Meis -- Pathogenesis and Prediction of Preterm Delivery / Catalin S Buhimschi, Charles J Lockwood -- Preterm Premature Rupture of Membranes / Brian M Mercer -- Management of Preterm Labor / Vincenzo Berghella -- Placenta Previa and Related Placental Disorders / Yinka Oyelese -- Complications of Labor and Delivery. Prolonged Pregnancy / Teresa Marino, Errol R Norwitz -- Induction of Labor / Nicole M Petrossi, Deborah A Wing -- Cesarean Delivery / Michael W Varner -- Vaginal Birth after Cesarean Delivery / Mark B Landon -- Breech Delivery / Edward R Yeomans, Larry C Gilstrap -- Operative Vaginal Delivery / Edward R Yeomans -- Obstetric Analgesia and Anesthesia / Gilbert J Grant -- Patient Safety / Christian M Pettker -- Neonatal Encephalopathy and Cerebral Palsy / Maged M Costantine, Mary E D'Alton, Gary D V Hankins -- Procedures. Genetic Amniocentesis and Chorionic Villus Sampling / Ronald J Wapner -- Fetal Surgery / Robert H Ball, Hanmin Lee -- Index.
  • XML -- Querying -- Querying XML -- Metadata, an overview -- Structural metadata -- The XML information set (Infoset) and beyond -- Managing XML : transforming and connecting -- Storing : XML and databases -- XPath 1.0 and XPath 2.0 -- Introduction to XQuery 1.0 -- XQuery 1.0 definition -- What's missing? -- XQuery APIs -- SQL/XML -- XML-derived markup languages -- Internationalization : putting the "W" in "WWW" -- Finding stuff.
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  • This original fourteen chapter book is a brief, slightly autobiographic tale of medical oncologists, surgeons, radiation oncologists, and breast cancer patients in a well-established cancer center in Texas, who pursued the goal of cure for breast cancer. The evolution of improved outcomes in the treatment of microscopic metastatic breast cancer is also the story of the development of adjuvant chemotherapy for post-operative breast disease. The adjuvant therapy of breast cancer came about with the realization that this malignancy, when diagnosed in most patients, had spread beyond the confines of the primary cancer.
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    Introduction / Brian D. Hodges and Lorelei Lingard -- 1. The shifting discourses of competence / Brian D. Hodges -- 2. Rethinking competence in the context of teamwork / Lorelei Lingard -- 3. Perturbations: the central role of emotional competence in medical training / Nancy McNaughton and Vicki LeBlanc -- 4. Competence as expertise: exploring constructions of knowledge in expert practice / Maria Mylopoulos -- 5. Assessing competence: extending the approaches to reliability / Lambert W.T. Schuwirth and Cees P.M. van der Vleuten -- 6. Blinded by "insight": self-assessment and its role in performance improvement / Kevin W. Eva, Glenn Regehr, and Larry D. Gruppen -- 7. The competent mind: beyond cognition / Annie S.O. Leung, Ronald M. Epstein, and Carol-Anne E. Moulton.
  • "One hundred years ago, Abraham Flexner's report on Medical Education in the United States and Canada helped establish the modern paradigm of premedical and medical education. Barr's research finds the system of premedical education that evolved to be a poor predictor of subsequent clinical competency and professional excellence, while simultaneously discouraging many students from under represented minority groups or economically disadvantaged backgrounds from pursuing a career as a physician. Analyzing more than fifty years of research, Barr shows that many of the best prospects are not being admitted to medical schools with long-term adverse consequences for the U.S. medical profession."--BOOK JACKET.
  • 2011 AccessMedicine
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    What is an electrocardiogram? -- Cardiac cells -- Anatomy of the heart and the electrical conduction system -- PQRSTU waves, complexes, intervals, and segments -- ECG graph paper and measurements -- Determination of heart rate and normal heart rhythms -- Normal 12-lead ECG configurations -- QRS axis -- 12-lead ECG interpretation -- Hypertrophy -- Intraventricular conduction disturbances -- Ischemia, injury, and infarction -- Miscellaneous effects -- Differential diagnosis -- Review ECGs -- Arrhythmias -- Review arrhythmia strips.
  • Quick answers surgery 2010
    A diagnostic index of over 100 symptoms and signs.
  • 2011 AccessMedicine
  • For important information you need to know, but can't remember, turn to QUICK HITS IN EMERGENCY MEDICINE. This practical, short compendium contains the key decision-rules, clinical values, mnemonics, and dosages that you need at your finger tips in the ED. It covers everything from acute coronary syndrome and ACLS, to electrolyte equations and hyperkalemia, to ventilator settings by disease to Wellen's syndrome. Information on each topic is limited to a single page and presented in easily digested formats such as tables, algorithms, bulleted lists, and clinical illustrations.
  • Quinones and quinone enzymes. Part A-B pt. A-B, 2004.
    pt. B ScienceDirect
  • Medical healing implies knowledge of the assumptions that underlie our understanding of 'health', and, concomitantly, how we define well being and its opposites, illness and disease. Today, health, health care (business, wellness, recreation), and medicine (especially research-driven scientific medicine) have become separate entities with different institutions, budgets, marketing philosophies and 'corporate cultures'. Furthermore, healing is individual and subjective, yet at the same time also culturally determined. The present volume brings together papers on these topics in an unique interdisciplinary approach. The book provides an ethical framework for healthcare from a political perspective. It discusses definitions of the terminology of healing and health and their ethical and medical implications including their historical contexts. A separate section expands the theme of the cultural constructedness of healing by the concepts of traditional Chinese medicine and homeopathy. Modern medicine has a strong focus on acute care, which urgently needs to place greater emphasis on preventive medicine including the crucial importance of social factors on health and on the emergence of 'public health'. The point of view of Business Concepts, their potential and limitations are by no means neglected and the legal ramifications of genetic research and innovative medical strategies with regard to some of our most foundational notions are discussed.
  • Bioassays of quorum sensing compounds using Agrobacterium tumefaciens and Chromobacterium violaceum -- Detection of 2-alkyl-4-quinolones using biosensors -- FRET-based biosensors for the detection and quantification of AI-2 class of quorum sensing compounds -- Isolation of agr quorum sensing autoinducers -- Liquid chromatography/mass spectrometry for the detection and quantification of N-acyl-l-homoserine lactones and 4-hydroxy-2-alkylquinolines -- Detection of autoinducer (AI-2)-like activity in food samples -- Detection of bacterial signaling molecules in liquid or gaseous environments -- Determination of acyl homoserine lactone and tetramic acid concentrations in biological samples -- Luminescent reporters and their applications for the characterization of signals and signal-mimics that alter LasR-mediated quorum sensing -- Modulation of mammalian cell processes by bacterial quorum sensing molecules -- Imaging N-acyl homoserine lactone quorum sensing in vivo -- Defining the structure and function of acyl-homoserine lactone autoinducers -- Global expression analysis of quorum-sensing controlled genes -- Small RNA target genes and regulatory connections in the Vibrio cholerae quorum sensing system -- Quantifying pseudomonas aeruginosa quinolones and examining their interactions with lipids -- Linking quorum sensing regulation and biofilm formation by Candida albicans -- Design of synthetic mammalian quorum-sensing systems -- Qualitative and quantitative determination of quorum sensing inhibition in vitro -- Custom synthesis of autoinducers and their analogues -- Heterologous overexpression, purification, and in vitro characterization of ahl lactonases -- High-performance liquid chromatography analysis of N-acyl homoserine lactone hydrolysis by paraoxonases -- Generation of quorum quenching antibodies.

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A repository of medical knowledge from internal medicine, cardiology, genetics, pharmacy, diagnosis and management, basic sciences, patient care, and more. Continuously expanding, all databases in the repository contain the latest editions of selected medical titles.MicroMedex: Premier pharmaceutical information source containing multiple databases and drug reference tools. Of particular value is DRUGDEX Evaluations, one of the most comprehensive drug sources available.DynaMed is a clinical information resource used by physicians to answer clinical questions quickly and easily at the point of care. Topics are updated daily as new evidence becomes available. Scopus is the largest abstract and citation database of peer-reviewed literature: scientific journals, books and conference proceedings.A drug information resource containing: American Hospital Formulary System (AHFS), drug formulary for Lucile Packard Children's Hospital (LPCH) and Stanford Hospital & Clinics (SHC), Lexi-Drugs (adverse reactions, dosage and administration, mechanism of action, storage, use, and administration information), Lexi-Calc, Lexi-ID, Lexi-I.V. Compatibility (King Guide), Lexi-Interact, and Lexi-PALS.Cumulative Index to Nursing and Allied Health Literature (CINAHL) contains coverage of nursing and allied health literature.A knowledge database that provides access to topic reviews based on over 6000 clinically relevant articles. The evidence-based content, updated regularly, provides the latest practice guidelines in 59 medical specialtiesProvides critical assessments of systematic reviews compiled from a variety of medical journals.Selects from the biomedical literature original studies and systematic reviews that are immediately clinically relevant and then summarizes these articles in an enhanced abstract with expert commentary.Multidisciplinary coverage of over 10,000 high-impact journals in the sciences, social sciences, and arts and humanities, as well as international proceedings coverage for over 120,000 conferences. Includes cited reference searching, citation maps, and an analyze tool.Features systematic reviews that summarize the effects of interventions and makes a determination whether the intervention is efficacious or not. Cochrane reviews are created through a strict process of compiling and analyzing data from multiple randomized control trials to ensure comprehensiveness and reliability.Provides systematic coverage of the psychological literature from the 1800s to the present through articles, book chapters and dissertations.BMJ Clinical Evidence. A clinical information tool built around systematic reviews summarizing the current state of knowledge about prevention and treatment of clinical conditions.PIER (Physicians' Information and Education Resource) is a Web-based decision-support tool designed for rapid point-of-care delivery of up-to-date, evidence-based guidance for primary care physicians.Cochrane Central Register of Controlled Trials (CENTRAL) provides access to 300,000 controlled trials that have been identified the Cochrane Collaboration.Provides drug information targeted for patients.A continually updating drug monograph.The National Guideline Clearinghouse (NGC): A comprehensive database of evidence-based clinical practice guidelines and related documents.MedlinePlus: A repository of health information from the National Library of Medicine. Links are from trusted sites. No advertising, no endorsement of commercial companies or productsLPCH CareNotes via MicroMedex: Patient education handouts customized by LPCH clinical staffMicromedex Lab Advisor: Evidence based laboratory test informationA drug database organized by generic name, trade name and drug class.LPCH / Stanford Hospital Formulary.A goldmine of trusted consumer health information from the world's largest medical library.A trusted source of expert advice for and about kids, providing the information necessary to help patients and parents understand their unique needs.Provides patient handouts from the American Academy of Family Physician.Access to the Stanford Health Library for patients.Lane provides access to over 5,000 eBooks many of which provide helpful background material that will prepare you to better tackle primary literature.Largest, broadest eBook package; covers all sciences, as well as technology (including software), medicine, and humanities. In addition to covering Wiley and Springer, MyiLibrary is also the only provider for Oxford and Cambridge University Press titles. No seat restrictions.A collection of biomedical books that can be searched directly by concept, and linked to terms in PubMed abstracts.
Large number of high quality software and database programming titles from O'Reilly. Other software titles are also available from Sams and Prentice Hall. Limited to 7 concurrent users.Vast collection of software and database programming titles from multiple publishers, including Microsoft Press.Largest provider of engineering-related eBooks; includes titles in computer science and biomedical engineering.Over 4,000 full-text e-books covering scientific and technical information from CRC Press and others. Many handbooks and single volume reference sources.Includes peer-reviewed life science and biomedical research protocols compiled from Methods in Molecular Biology, Methods in Molecular Medicine, Methods in Biotechnology, Methods in Pharmacology and Toxicology, Neuromethods, the Biomethods Handbook, the Proteomics Handbook, and Springer Laboratory Manuals.Contains full text access to selected biomedical and nursing books.Provides online, full-text access to Springer's journal titles as well as journals from other publishers. Subjects include: life sciences, chemical sciences, environmental sciences, geosciences, computer science, mathematics, medicine, physics and astronomy, engineering and economics. Also includes eBooks.Collection of over 8 thousand fulltext titles in engineering, math, and basic and applied biomedical research. Coverage is from 1967 to the present.A library of ebooks on a wide array of topics, digitized and made available online in conjunction with the original publishers.