Lane Medical Library

TP53 mutations in human cancers : selection versus mutagenesis / Magali Olivier, Audrey Petitjean, Claude Caron de Fromentel, and Pierre Hainaut -- Lessons on p53 from mouse models / Dadi Jiang and Laura D. Attardi -- TP63, TP73 : the guardian's elder brothers / Stephanie Courtois, Pierre Hainaut and Claude Caron de Fromentel -- The regulation of p53 protein function by phosphorylation / Nicola J. Maclaine and Theodore Hupp -- The p53-Mdm2 loop : a critical juncture of stress response / Yaara Levav-Cohen, Zehavit Goldberg, Osnat Alsheich Bartok, Valentina Zuckerman, Sue Haupt and Ygal Haupt -- Cooperation between MDM2 and MDMX in the regulation of p53 / Jeremy Blaydes -- Regulation and function of the original p53-inducible p21 gene / Jennifer A. Fraser -- p53 localization / Carl G. Maki -- Modes of p53 interactions with DNA in the chromatin context / Vladana Vukojevic, Tatiana Yakovleva, and Georgy Bakalkin -- p53's dilemma in transcription : analysis by microarrays / Karuppiah Kannan, Gideon Rechavi and David Givol -- Tumor viruses and p53 / Nobuo Horikoshi -- p53 and immunity / Vikram Narayan, Sarah E. Meek and Kathryn L. Ball.

The peculiarities of infant respiratory physiology / Hammer, J., Eber, E. -- Tidal breathing measurements / Lodrup Carlsen, K.C., Carlsen, K.-H. -- Respiratory mechanics / Davis, S.D., Gappa, M., Rosenfeld, M. -- Forced expiratory flow-volume measurements / Modl, M., Eber, E. -- Infant whole-body plethysmography / Gappa, M., Heulskamp, G. -- Measurement of functional residual capacity and ventilation inhomogeneity by gas dilution techniques / Gustafsson, P.M., Ljungberg, H. -- Techniques for the measurement of lung function in toddlers and preschool children / Hall, G.L., Brookes, I.M. -- Applications and future directions of infant pulmonary function testing / Stocks, J., Lum, S. -- Spirometry: volume-time and flow-volume curves / Eber, E., Zach, M.S. --Plethysmography and gas dilution techniques / Marchal, F., Schweitzer, C. -- Reference equations for ventilatory function measurements in children from 6 to 16 years / Merkus, P.J.F.M. -- Measurement of bronchial responsiveness in children / Barben, J., Riedler, J. -- Measurements of respiratory muscle function in children / Fauroux, B., Lofaso, F. -- Measurements of thoraco-abdominal asynchrony and work of breathing in children / Newth, C.J.L., Hammer, J. -- Lung diffusion capacity / de Jongste, J.C., Merkus, P.J.F.M., Stam, H. -- Measurement of exhaled nitric oxide / Kharitonov, S.A. -- Measurement of nasal nitric oxide / Corbelli, R., Hammer, J. -- Exhaled breath condensate and other markers in exhaled air / Moeller, A., Kielbasa, B. --Childhood asthma and wheezing disorders / Basek, P., Straub, D., Wildhaber, J.H. -- Cystic fibrosis / Ratjen, F. -- Lung transplantation in pediatric patients / Tablizo, M.A., Woo, M.S. -- Neuromuscular disorders / Mellies, U., Dohna-Schwake, C. -- Paediatric oncology and bone marrow transplantation / Cerveri, I. ... [et al.] -- Long-term sequelae of neonatal lung disease / Trachsel, D., Coates, A.L. -- Pulmonary function testing in the neonatal and paediatric intensive care unit / Hammer, J., Newth, C.J.L.

Section 1. Pain and neurology -- Section 2. The neurobiology of pain -- Peripheral signaling of pain -- Spinal cord processing -- Supraspinal processing -- Endogenous pain modulation -- Section 3. The pathophysiology of pain -- Section 4. Pain assessment -- Neurophysiological examinations in neuropathic pain -- Section 5. Pain conditions in neurology: peripheral neuropathies -- Pain after nerve injury -- Facial pain -- Polyneuropathies and pain -- Section 6. Pain conditions in neurology: central neuropathic pain -- Section 7. Other pain conditions of neurological interest -- Section 8. Treatment of neuropathic pain -- Subject index.

Pain management in interventional radiology : an introduction / Jason R. Bauer and Charles E. Ray, Jr. -- Clinical evaluation of low-back pain / Anthony P. Dwyer, Curt Freudenberger, and Vikas V. Patel -- Local anesthetics / Jan Namyslowski -- Functional lumbar spine anatomy : a review / Anthony P. Dwyer ... [et al.] -- Percutaneous vertebroplasty / Mitchell T. Smith and Charles E. Ray, Jr. -- Kyphoplasty / Frances D. Faro, Anthony P. Dwyer, and Vikas V. Patel -- Epidural steroid injections / Brian D. Petersen, Kirkland W. Davis, and James Choi -- Selective nerve root blocks / Brian Petersen, Kirkland W. Davis, and James Choi -- Discography / Charles E. Ray, Jr. and Leo J. Rothbarth -- Facet (zygapophyseal) joint injections / Nick Stence -- Articular interventions in pain management : a general approach / Blaze Cook -- Percutaneous management of visceral pain / Frank Morello -- Embolization of painful neoplasms / Jennifer R. Huddleston and Stephen P. Johnson -- Image-guided ablation of painful osteolyses / David T. Wang and Charles E. Ray, Jr. -- Chronic pelvic pain in women / Derek L. West -- Sedation and analgesia medications / George Behrens, Hector Ferral, and Nilesh H. Patel -- Guidelines for sedation administered by nonanesthesiologists / Iftikhar Ahmad -- Pediatric sedation for radiological imaging studies and interventions / Keira P. Mason -- Nontraditional pain management in interventional radiology / Salomao Faintuch ... [et al.] -- Postprocedural pain control / Stan Zipser.

Mechanistic dissection of pain: from DNA to animal models / Z. David Luo -- Assessment of acute thermal nociception in laboratory Animals / Jeffrey W. Allen and Tony L. Yaksh -- Tissue injury models of persistent nociception in rats / Jeffrey W. Allen and Tony L. Yaksh -- Segmental spinal nerve ligation model of neuropathic pain / Jin Mo Chung, Hee Kee Kim, and Kyungsoon Chung -- Partial sciatic nerve transection / Thies Lindenlaub and Claudia Sommer -- Modeling diabetic sensory neuropathy in rats / Nigel A. Calcutt -- Sciatic inflammatory neuropathy in the rat: surgical procedures, induction of inflammation, and behavioral testing / Erin D. Milligan, Steven F. Marier, and Linda R. Watkins -- A rat pain model of vincristine-induced neuropathy / Emiliano S. Higuera and Z. David Luo -- Loop dialysis catheter: a technology for chronic spinal dialysis in a freely moving rat / Martin Marsala -- Intrathecal catheterization and drug delivery in the rat / Shelle A. Malkmus and Tony L. Yaksh --Trigeminal neuronal recording in animal models of orofacial pain / Koichi Iwata, Yuji Masuda, and Ke Ren -- In vivo electrophysiology of dorsal-horn neurons / Louise C. Stanfa and Anthony H. Dickenson -- Single fiber recording: in vivo and in vitro preparations / Maria Schäfers and David Cain -- Anatomical identification of neurons responsive to nociceptive stimuli / Luc Jasmin and Peter T. Ohara -- Isolation and culture of sensory neurons from the dorsal-root ganglia of embryonic or adult rats / Thomas H. Burkey, Cynthia M. Hingtgen, and Michael R. Vasko -- Primary cultures of neonatal rat spinal cord / Virginia S. Seybold and Lia G. Abrahams -- Single-cell laser capture microdissection and RNA amplification -- Fredrik Kamme ... [et al.] -- Semi-quantitative real-time PCR for pain research / Hong Qing Guo and Sandra R. Chaplan -- Functional genomic analysis in pain research using hybridization arrays / Stephen J. Walker ... [et al.] -- Generation of transgenic mice / Guoping Feng, Jing Lu, and Jimmy Gross -- Knockout mouse models in pain research / Andrée Dierich and Brigitte L. Kieffer.

Introduction --Measuring pain intensity --Measuring pain quality --Measuring pain location --Measuring pain behavior --Measuring pain interference --Measuring sleep quality --Measuring depression --Measuring general physical functioning --Measuring alcohol and drug use --Measuring global improvement and satisfaction with pain care --References.

Introduction to Diabetic Neuropathies -- Classification and Clinical Features -- Diagnosis and Staging -- Management of Neuropathic Pain.

Great plagues of the past and remaining questions / Cheston B. Cunha and Burke A. Cunha -- Identification and interpretation of historical cemeteries linked to epidemics / Dominique Castex -- Archaeological proof of an abrupt mortality crisis : simultaneous deposit of cadavers, simultaneous deaths? / Henri Duday -- Molecular detection of past pathogens / Michel Drancourt and Didier Raoult -- Histologic detection of past pathogens / Hubert Lepidi -- Palaeomicrobiology of tuberculosis / Helen D. Donoghue -- Past leprae / Andreas G. Nerlich and Albert R. Zink -- Archaeology of human pathogens : palaeopathological appraisal of palaeoepidemiology / Olivier Dutour -- Past plague / Michel Drancourt and Didier Raoult -- Typhoid fever epidemic in ancient Athens / Manolis J. Papagrigorakis, Christos Yapijakis and Philippos N. Synodinos -- Dental pulp as a tool for the retrospective diagnosis of infectious diseases / Vu Dang La ... [et al.] -- History of influenza pandemics / Bruno Lina -- Human lice : Pediculus and Pthirus / Kosta Y. Mumcuoglu.

Paleoradiology : history and new developments / Rethy K. Chhem -- Paleoradiologic techniques / George Saab, Rethy K. Chhem, and Richard N. Bohay -- The taphonomic process, biological variation, and x-ray studies / Don R. Brothwell -- Diagnostic paleoradiology for paleopathologists / Rethy K. Chhem, George Saab, and Don R. Brothwell -- Paleoradiology in the service of zoopaleopathology / Don R. Brothwell -- Normal variations in fossils and recent human groups / Don R. Brothwell -- Concluding comments / Rethy K. Chhem and Don R. Brothwell.

Global Palliative Care Issues / Marissa Slaven -- Palliative Care Communication Issues / Joshua Hauser -- Nutritional Palliative Care Issues / Clay M. Anderson -- Psychiatric Palliative Care Issues / Jane E. Loitman and Teresa Deshields -- Cardiac Palliative Care Issues / David Wensel and Drew A. Rosielle -- Pulmonary Palliative Care Issues / Karin B. Porter-Williamson -- GI Palliative Care Issues / Eric Roeland and Gary Buckholz -- Palliative Pain Issues / Miles J. Belgrade -- Palliative Wound and Skin Issues / Cynthia A. Worley -- Issues in the Last Hours / Jane E. Loitman and Christian T. Sinclair.

v. 1. Chapters 1-25 -- v. 2. Chapters 26-54.

Anatomy of the pancreas / Mary Kay Washington -- -- Pathology of the exocrine pancreas / Ralph H. Hruban, Syed Z. Ali -- Molecular genetic alterations in cancer-associated genes / Michiel S. van der Heijden, Scott E. Kern -- Molecular signal pathways in pancreatic cancer / Nabeel Bardeesy -- Pancreatic development / John W. Lin, Steven D. Leach -- Mouse-models of exocrine pancreatic cancer / Eric P. Sandgren -- Epidemiology / Donghui Li, Li Jiao -- Hereditary pancreatitis and its link to pancreatic cancer / Saima Sharif ... [et al.] -- Familial pancreatic cancer / Ralph Hruban ... [et al.] -- Prevention / Marsha L. Frazier -- -- Pancreatic cancer: clinical presentation / Vincent J. Picozzi -- Radiographic imaging: CT/MR/PET / Eric Tamm ... [et al.] -- Endoscopic staging: EUS, ERCP / Richard A. Erickson -- Laparoscopic staging / Olga N. Tucker, Kevin C. Conlon -- Fine-needle aspiration biopsy of the pancreas: indications and interpretations / Gregg A. StaerkelClinical trial design and methodology / Jason A. Konner, Eileen M. O'Reilly -- Supportive care: symptom management / Suresh K. Reddy, Ahmed Elsayem, Rudranath Talukdar -- Supportive care: cachexia and anorexia syndrome / Michael J. Tisdale -- -- Target discovery: genomics/proteomics / Christine A. Iacobuzio-Donahue -- Gene therapy and virotherapy of pancreatic cancer / Masato Yamamoto, David T. Curiel -- Antiangiogenic therapy for pancreatic cancer / Chandrajit P. Raut, Lee M. Ellis -- Vaccines / Daniel A. Laheru, Elizabeth M. Jaffe --Serologic diagnosis of pancreatic cancer / Matthew H. Katz, Abdool R. Moossa, Michael Bouvet -- The Molecular diagnosis of pancreatic cancer / Michael G. Goggins -- -- Pancreaticoduodenectomy / Tina W. F. Yen ... [et al.] -- The Role of total pancreatectomy in the treatment of pancreatic cancer / John D. Christein, Michael B. Farnell -- Distal pancreatectomy / Scott F. Gallagher, Emmanuel E. Zervos, Michel M. Murr -- Pylorus preservation versus standard pancreaticoduodenectomy / Taylor S. Riall, Charles J. Yeo -- Pancreaticoduodenectomy with en bloc vascular resection and reconstruction for localized carcinoma of the pancreas / Charles R. Scoggins, Jeffrey E. Lee, Douglas B. Evans -- Reducing the risk of pancreaticoduodenectomy / Laura A. Lambert, John D. Birkmeyer -- Interventional radiology in the management of postoperative complications / Michael J. Wallace, Stephen McRaeThe Principles of chemoradiation in localized pancreatic cancer / Christopher H. Crane -- Adjuvant and neoadjuvant therapies for resectable pancreatic cancer / Robert A. Wolff -- Postoperative adjuvant therapy and the rationale for the U.S. intergroup trial / Young Kwok, Michael C. Garofalo, William F. Regine -- Intraoperative electron beam irradiation in pancreatic cancer / Christopher G. Willett, Peter J. Biggs, Carlos Fernández-del Castillo -- -- Systemic therapy and chemo-radiotherapy / Ross A. Abrams -- Endoscopic palliation of pancreatic cancer / David Whitaker, Benedict M. Deveraux -- Surgical palliation of pancreatic cancer / Michael L. Kendrick ... [et al.] -- -- Advanced metastatic disease / Marcel Rozencweig, Daniel D. Von HoffTumors of the endocrine system / David S. Klimstra -- Sporadic gastrinoma / Chandu Vemuri, Gerard M. Doherty -- Rare functioning tumors: VIPoma, glucagonoma, somatostatinoma / Geoffrey B. Thompson -- Pancreatic endocrine neoplasms in multiple endocrine neoplasia type 1 / Maria A. Kouvaraki ... {et al.] -- The von Hippel-Landau syndrome / Eric Jonasch -- Non-functioning pancreatic endocrine tumors / Carmen C. Solorzano, Jeffrey E. Lee -- Management of metastatic islet cell carcinoma / James C. Yao, Maria A. Kouvaraki, Sanjay Gupta -- -- Pathology of periampullary tumors / Mari Mino, Gregory Y. Lauwers -- Clinical management of ampullary tumors / Rebekah R. White ... [et al.] -- -- Pathological classification of cystic neoplasms of the pancreas / N. Volkan Adsay -- Imaging of cystic pancreatic tumors / Chusilp Charnsangavej, Eric P. Tamm -- Surgical treatment of cystic neoplasms / Carlos Fernández-del Castillo -- -- Tumors of the distal common bile duct / Jorge Abores-Saavedra.

Introduction to Pancreatic Cytopathology -- Pancreatic Cytopathology: A Pragmatic Approach -- Pancreatic Ductal Adenocarcinoma and Its Variants -- Ancillary Testing for the Diagnosis of Pancreatic Ductal Adenocarcinoma -- Acinar Cell Carcinoma -- Pancreatoblastoma -- Solid-Pseudopapillary Neoplasm -- Pancreatic Endocrine Tumors -- Cystic Muscus-Producing Neoplasia: Intraductal Papillary Mucinous Neoplasms and Mucinous Cystic Neoplasms -- Other Cystic Lesions of the Pancreas -- Inflammatory Disease of the Pancreas -- Secondary Malignancies of the Pancreas.

Part 1. Potential Trials in Acute Pancreatitis -- Acute Pancreatitis in Intensive Care / John Kinsella, Barry Clements, Euan Dickson, Thierry Dugernier and Martin Hughes -- Antibiotic Prophylaxis in Acute Severe Pancreatitis: Should We Have a Further Study? / Jens Werner, Kevin C. P. Conlon, Hjalmar C. van Santvoort, Caroline S. Verbeke and Sakhawat H. Rahman -- Designing an Optimal Study for the Management of Infected Pancreatic Necrosis / Marc G. H. Besselink, Hjalmar C. van Santvoort, Ross Carter, Richard M. Charnley and Damian J. Mole, et al. -- Nutrition in Acute Pancreatitis / Hemant M. Kocher, Christos Dervenis, Attila Oláh, William R. Murray and Barry Clements, et al. -- An Optimal Randomized Study for Pain Control in Acute Pancreatitis / Åke Andrén-Sandberg, Julia V. Mayerle, Ajith K. Siriwardena, David P. Berry and Gareth R. Kirk, et al. -- Part 2. Potential Trials in chronic Pancreatitis -- Endoscopic Versus Surgical Drainage for Chronic Pancreatitis / Stephen P. Pereira, Shivi S. Siva and Colin D. Johnson -- Duodenum-Preserving Pancreatic Resection with Pancreatic Duct Drainage: What Is the Role of Supraduodenal Biliary Drainage? / Emre F. Yekebas, Christos Dervenis, Richard M. Charnley, Bettina M. Rau and Jens Werner, et al. -- Part 3. Potential Trials in Pancreatic Cancer -- Pain Management and Nutritional Support in Nonresectable Pancreatic Cancer / David P. Berry, Richard M. Charnley, Christos Dervenis, Gareth R. Kirk and Francis Regan, et al. -- Endoscopic Therapy in the Palliation of Nonresectable Pancreatic Cancer / Attila Oláh, William R. Murray, Colin J. McKay, Åke Andrén-Sandberg and Sakhawat H. Rahman, et al. -- Pancreatic Endocrine Tumors / Damian J. Mole, Caroline S. Verbeke and Nicholas S. Reed -- The Role of the Systemic Inflammatory Response in Predicting Outcome in Patients with Pancreatic Cancer / Donald C. McMillan -- Part 4. Topic reviews -- Botulinum Toxin and the Sphincter of Oddi / William R. Murray -- The European Study Group for Pancreatic Cancer (ESPAC) Trials / Paula Ghaneh, Khaled Dajani, Michael G. T. Raraty, Robert Suttton and John P. Neoptolemos.

Epidemiology and pathophysiology of acute pancreatitis / Anil B. Nagar and Fred S. Gorelick -- Diagnosis and risk stratification of acute pancreatitis / Frank Burton -- Gallstone pancreatitis / Matthias Kraft and Markus M. Lerch -- Other causes of acute pancreatitis / Charles D. Ulrich -- Treatment of mild acute pancreatitis and prevention of post-ERCP pancreatitis / Michael Morelli and Lehel Somogyi -- Treatment of severe acute pancreatitis / Peter Draganov -- Pancreatic necrosis and infections in patients with acute pancreatitis / Michael L. Kendrick and Michael G. Sarr --Pancreatic fluid collections and pseudocysts in patients with acute pancreatitis / Michael F. Byrne and John Baillie -- Epidemiology of chronic pancreatitis / Albert B. Lowenfels and Patrick Maisonneuve -- Risk, etiology, and pathophysiology of chronic pancreatitis / David C. Whitcomb -- Natural history of chronic pancreatitis / Supot Pongprasobchai and Jonathan E. Clain -- Diagnosis of chronic pancreatitis / Chris E. Forsmark --Treatment of chronic pancreatitis pain: overview and medical management / Phillip P. Toskes -- Endoscopic approach to chronic pancreatitis / Lee McHenry, Glen Lehman, and Stuart Sherman -- Surgery for chronic pancreatitis / Martin D. Smith, Elias Degiannis, and Selwyn M. Vickers --Treatment of exocrine pancreatic insufficiency / Supot Pongprasobchai and Eugene P. DiMagno -- Complications of chronic pancreatitis / John Petersen and Chris E. Forsmark.

Influenza pandemics are unpredictable but recurring events that can have severe consequences on societies worldwide. This revised WHO guidance publication on pandemic influenza preparedness and response acknowledges that pandemic preparedness is centered around health sectors planning but must also be broader. WHO therefore advocates a "whole-of-society" approach to sustainable and ethical pandemic preparedness while focusing in more detail on the role of the health sector. The roles of WHO and national governments are outlined to create a better understanding of how health and non-health sectors, both public and private, all contribute to pandemic preparedness.--Publisher's description.

Pt. 1. Introductory background -- pt. 2. Paradigms in the arts and social sciences -- pt. 3. General-integrative paradigms in psychology -- pt. 4. Particular-specific paradigms in psychology -- pt. 5. Operational paradigms in psychology -- pt. 6. Conclusion.

Parallel and evolutionary approaches to computational biology /Nouhad Rizk --Parallel Monte Carlo simulation of HIV molecular evolution in response to immune surveillance /Jack da Silva --Differential evolutionary algorithms for in vivo dynamic analysis of glycolysis and pentose phosphate pathway in Escherichia coli /Andrei Doncescu --Compute-intensive simulations for cellular models /Kevin Burrage --Parallel computation in simulating diffusion and deformation in human brain /Jun Zhang --Computational molecular biology /Azzedine Boukerche --Special-purpose computing for biological sequence analysis /Bertil Schmidt --Multiple sequence alignment in parallel on a cluster of workstations /Amitava Datta --Searching sequence databases using high performance BLASTs /Xue Wu --Parallel implementations of local sequence alignment: hardware and software /Vipin Chaudhary --Parallel computing in the analysis of gene expression relationships /Robert Martino --Parallel algorithms for solving the fragment assembly problem in DNA strands /Enrique Alba --A cooperative genetic algorithm for knowledge discovery in microarray experiments /Mohammad Khabzaoui --Parallel and distributed computation of large phylogenetic trees /Alexandros P. Stamatakis --Phylogenetic parameter estimation on COWs /Ekkehard Petzold --High-performance phylogeny reconstruction under maximum parsimony /Tiffani Williams --Protein folding with the parallel replica exchange molecular dynamics method /Ruhong Zhou --High performance alignment methods for protein threading /R. Andonov --Parallel evolutionary computations in discerning protein structures /Richard O. Day --A brief Overview of Grid activities for bioinformatics and health applications /Ali Al Mazari --Parallel algorithms for bioinformatics /Shahid H. Bokhari --Cluster and grid infrastructure for computational chemistry and biochemistry /Kim K. Baldridge --Distributed workflows in bioinformatics /Arun Krishnan --Molecular structure determination on a computational and data grid /Russ Miller --GIPSY : a problem solving environment for bioinformatics applications /Rajendra R. Joshi --TaskSpaces : a software framework for parallel bioinformatics on computational grids /Hans De Sterck --The organic grid : self-organizing computation on desktop grids /Arjav J. Chakrvarti --FPGA Computing in modern bioinformatics /H. Simmler --Virtual microscopy : distributed image storage, retrieval, analysis, and visualization /T. Pan

Mating types in paramecium -- General description of the protista and of paramecium -- Methods of studying genetic processes in organisms of the paramecium Aurelia species group -- The determination of mating types in paramecium -- Symbionts and mitochondria of paramecium -- Determination of i-antigens -- Micronuclei and macronuclei -- Ribosomal RNA and DNA -- Cortical morphogenesis -- Behavior -- Epigenetics.

History -- Clinical findings, treatment and prognosis -- Pathogenesis -- Brain (cerebrum) -- Brain (cerebellum and brainstem) -- Spinal cord -- Cranial nerves -- Dorsal root ganglia and peripheral nerves -- Neuromuscular junction and muscle -- Systemic syndromes (with neurologic implications) -- Nuclear/nucleolar antibodies -- Cytoplasmic antibodies -- Synaptic/channel antibodies -- Anti-retinal/optic nerve antibodies -- Thoracic cancers -- Breast/gynecologic/testicular cancer -- Hematologic cancers/miscellaneous solid tumors.

Sequencing strategies for parasite genomes / Daniella Bartholomeu and Najib M. El-Sayed -- Annotation of parasite genomes / Matthew Berriman and Midori Harris -- Parasite genome databases and web-based resources / Christiane Hertz-Fowler and Neil Hall -- Expressed sequence tags: medium-throughput protocols / Claire Whitton ... [et al.] -- Expressed sequence tags: analysis and annotation / John Parkinson and Mark Blaxter -- Positive selection scanning of parasite DNA sequences / Winston A. Hide and Raphael D. Isokpehi -- RACE and RAGE cloning in parasitic microbial eukaryotes / Bryony A. P. Williams and Robert P. Hirt -- Amplified (restriction) fragment length polymorphism (AFLP) analysis / Daniel K. Masiga and C. Michael R. Turner -- Minisatellites and MVR-PCR for the individual identification of parasite isolates / Annette MacLeod -- Analysis of differentially expressed parasite genes and proteins using transcriptomics and proteomics / Daniel C. Gare --Gene expression studies using self-fabricated parasite cDNA microarrays / Karl F. Hoffmann and Jennifer M. Fitzpatrick -- DNA content analysis on microarrays / Upinder Singh, Preetam H. Shah, and Ryan C. MacFarlane -- Typing single-nucleotide polymorphisms in Toxoplasma gondii by allele-specific primer extension and microarray detection / Chunlei Su ... [et al.] -- Transfection of the human malaria parasite plasmodium falciparum / Brendan S. Crabb ... [et al.] -- A PCR-based method for gene deletion and protein tagging in Trypanosoma brucei / George K. Arhin ... [et al.] -- Analysis of gene function in Trypanosoma brucei using RNA interference / Appolinaire Djikeng ... [et al.] -- In vitro shuttle mutagenesis using engineered mariner transposons / Kelly A. Robinson, Sophie Goyard, and Stephen M. Beverley -- Random mutagenesis strategies for construction of large and diverse clone libraries of mutated DNA fragments / Sudsanguan Chusacultanachai and Yongyuth Yuthavong -- Separation, digestion, and cloning of intact parasite chromosomes embedded in agarose / Vanessa Leech, Michael A. Quail, and Sara E. Melville -- Chromosome fragmentation in Leishmania / Pascal Dubessay ... [et al.] --FISH mapping for helminth genomes / Hirohisa Hirai and Yuriko Hirai -- Fiber-FISH: fluorescence in situ hybridization on stretched DNA / Klaus Ersfeld -- Yeast two-hybrid assay for studying protein-protein interactions / Ahmed Osman -- From genomes to vaccines for leishmaniasis / Carmel B. Stober.

"Parasitoids are parasitic insects that kill their insect hosts in immature pre-reproductive stages. Parasitoids are employed in biological control programs worldwide to kill insect pests and are environmentally safe and benign alternatives to chemical pesticides. As resistance to chemical pesticides continues to escalate in many pest populations, attention is now refocusing on biologically based strategies to control pest species in agriculture and forestry as well as insect vector populations that transmit human and animal diseases. Parasitoids are an economically critical element in this equation and in integrated pest management. Viruses have evolved intimate associations with parasitoids, and this book features a large section on symbiotic viruses that are integrated into the wasp chromosomal DNA (polydnaviruses). A separate section on parasitoid venoms, which are of interest to the pharmaceutical and medical communities as well as insect-oriented biologists, is also featured"--Back cover.

Depression / William J. Burke, Steven P. Wengel, and Daryl Bohac -- Anxiety / Hubert H. Fernandez and Tanya Simuni -- Obsessionality / Marie-Andrée Bruneau -- Dementia / Patricia Kavanagh and Karen Marder -- Psychosis / Eric S. Molho and Stewart A. Factor -- Postsurgical behavioral changes / Laurie M. Rilling, John A. Lucas, and Ryan J. Uitti -- Dysphagia / Norman A. Leopold -- Gastric dysfunction / Tanya Gurevich, Amos D. Korczyn, and Nir Giladi -- Intestinal dysfunction / Ronald F. Pfeiffer --Impaired sexual function / Cheryl Waters and Janice Smolowitz -- Urological dysfunction / Carlos Singer -- Cardiovascular autonomic dysfunction / David S. Goldstein -- Thermoregulatory dysfunction / Mark S. LeDoux -- Respiratory dysfunction / Holly A. Shill -- Insomnia / Maria L. Moro-de-Casillas and David E. Riley -- Rapid eye movement sleep behavior disorder / Suzanne Stevens and Cynthia Comella -- Excessive daytime sleepiness / David Hardesty, Daryl Victor, and Steven J. Frucht --Sleep apnea / Cheryl M. Carlucci and Robert A. Hauser -- Visual dysfunction / Robert L. Rodnitzky -- Primary visual and visuocognitive deficits / Ivan Bodis-Wollner and Andrea Antal -- Olfactory dysfunction / Sarah Furtado and Zbigniew K. Wszolek -- Pain syndromes and disorders of sensation / Blair Ford and Ronald F. Pfeiffer -- Oculomotor dysfunction / Parashkev Nachev and Christopher Kennard -- Fatigue / Carol Ewing Garber and Joseph H. Friedman.

An introduction to particle toxicology: from coal mining to nanotechnology / Paul J.A. Borm and Ken Donaldson -- Mineralogy and structure of pathogenic particles / Tim Jones and Kelly Bérubé -- Particle dosimetry: deposition and clearance from the respiratory tract and translocation towards extra-pulmonary sites / Wolfgang G. Kreyling ... [et al.] -- Particulate air pollutants and small airway remodeling / Andrew Churg -- Particle-mediated extracellular oxidative stress in the lung / Frank J. Kelly and Ian S. Mudway -- Particles and cellular oxidative and nitrosative stress / Dale W. Porter, Stephen S. Leonard, and Vincent Castranova -- Interaction of particles with membranes / Barbara Rothen-Rutishauser, Samuel Schurch, and Peter Gehr -- Particle-associated metals and oxidative stress in signaling / James M. Samet and Andrew J. Ghio -- Proinflammatory effects of particles on macrophages and epithelial cells / Vicki Stone ... [et al.] -- Cell-signaling pathways elicited by particulates / Jamie E. Levis and Brooke T. Mossman -- Particle-associated organics and proinflammatory signaling / Francelyne Marano, Sonja Boland, and Armelle Baeza-Squiban -- The asbestos model of interstitial pulmonary fibrosis: TNF-a and TGF-b1 as mediators of asbestos-induced lung fibrogenesis / Deborah E. Sullivan and Arnold R. Brody --Effects of particles on the immune system / M. Ian Gilmour, Tina Stevens, and Rajiv K. Saxena -- Effects of particles on the cardiovascular system / Nicholas L. Mills ... [et al.] -- Susceptibility to particle effects / Steven R. Kleeberger and Reuben Howden -- Genotoxic effects of particles / Roel P.F. Schins and Tom K. Hei -- Approaches to the toxicological testing of particles / Ken Donaldson ... [et al.] -- Models for testing the pulmonary toxicity of particles: Lund bioassay screening studies in male rats with a new formulation of TIO2 particulates / David B. Warheit, Kenneth L. Reed, and Christie M. Sayes -- Air pollution and human brain pathology: a role for air pollutants in the pathogenesis of Alzheimer's disease / Lilian Calderón-Garcidueñas and William Reed -- Biologically based lung dosimetry and exposure-dose-response models for poorly soluble inhaled particles / Lang Tran and Eileen Kuempel -- Nanoparticles in medicine / Paul J.A. Borm and Detlef Muller-Schülte -- The toxicology of inhaled particles: summing up an emerging conceptual framework / Den Donaldson, Lang Tran, and Paul J.A. Borm.

Pasteurella multocida: Diseases and Pathogenesis /I. W. Wilkie, M. Harper, J. D. Boyce and B. Adler --Pathogenomics of Pasteurella multocida /J. D. Boyce, T. Seemann, B. Adler and M. Harper --The Key Surface Components of Pasteurella multocida: Capsule and Lipopolysaccharide /Marina Harper, John D. Boyce and Ben Adler --Pasteurella multocida and Immune Cells /Katharina F. Kubatzky --Molecular Biology of Pasteurella multocida Toxin /Joachim H. C. Orth and Klaus Aktories --Pasteurella multocida Toxin Interaction with Host Cells: Entry and Cellular Effects /Brenda A. Wilson and Mengfei Ho --Swine Atrophic Rhinitis Caused by Pasteurella multocida Toxin and Bordetella Dermonecrotic Toxin /Yasuhiko Horiguchi --The Pasteurella multocida Toxin: A New Paradigm for the Link Between Bacterial Infection and Cancer /Alistair Lax.

Pathophysiology of anterior knee pain -- Pathophysiology of lateral patellar dislocation -- Natural history of patellofemoral dislocations -- Clinical presentation of patellofemoral disorders -- Clinical examination of the patellofemoral patient -- Standard X-ray examination: patellofemoral disorders -- Patellar height: which index? -- Stress radiographs in the diagnosis of patellofemoral instability -- Computed tomography and arthro-CT scan in patellofemoral disorders -- MRI analysis of patella instability factors -- MRI of the patellofemoral articular cartilage -- Patellofemoral pain syndrome: the value of pinhole and SPECT scintigraphic imaging and quantitative measurements of bone mineral equivalent density with quantitative computed tomography -- Gait analysis in patients with patellofemoral disorders -- Iatrogenic anterior knee pain with special emphasis on the clinical radiographical, histological, ultrastructural and biochemical aspects after anterior cruciate ligament reconstruction using ipsilateral autografts -- Non-operative treatment of patellofemoral pain: role of physical therapy -- Lateral release of the lateral patellofemoral retinaculum: literature review for select patellofemoral disorders -- Medial side patellofemoral anatomy -- Arthroscopic medial reefing in acute patellar dislocation -- Medial reefing in chronic potential patellar instability -- Medial patellofemoral ligament reconstruction -- MPFL reconstruction: the adductor sling approach -- Importance and radiographic identification of the femoral insertion in medial patellofemoral ligament reconstruction -- MPTL (medial patellotibial ligament) reconstruction -- Distal realignment: medialization of tibial tuberosity: the Elmslie-Trillat technique -- Bony surgery distal realignment surgery -- Trochlear lengthening osteotomy with or without elevation of the lateral trochlear facet -- Proximal open trochleoplasty (grooveplasty) -- Deepening trochoplasty for patellar instability -- Arthroscopic deepening trochleoplasty for patella instability -- The role of limb rotational osteotomy -- Long-term results after autologous chondrocyte implantation in cartilage lesions of the patellofemoral joint -- Novel nano-composite multilayered biomaterial for the treatment of patellofemoral cartilage lesions -- Isolated patellofemoral osteoarthritis: natural history and clinical presentation -- The nonoperative treatment of patellofemoral arthritis -- Current concepts regarding tibial tubercle osteotomy -- Isolated patellofemoral osteoarthritis: prosthetic indications -- Post-operative management of surgeries aimed at correcting patellofemoral instability: results of an international surgeon survey -- Errors and complications in patellofemoral surgery -- Trochleoplasty for symptomatic trochlear dysplasia in the skeletally immature patient with review of fetal anatomy -- Patellofemoral disorders in the skeletally immature patients.

Bacterial toxins as immunomodulators / David S. Donaldson and Neil A. Williams -- Innate immune evasion by staphylococci / Karin Ellen Veldkamp and Jos A.G. van Strijp -- Bacterial complement escape / Ilse Jongerius, Sanjay Ram, and Suzan Rooijakkers -- Modulation of innate immune signalling pathways by viral proteins / Orla Mulhern, Barry Harrington, and Andrew G. Bowie -- Viral TNF inhibitors as potential therapeutics / Masmudur M. Rahman, Alexandra R. Lucas, and Grant McFadden -- Lipoxins as an immune-escape mechanism / Fabiana S. Machado and Julio Aliberti -- Immunomodulatory activity and therapeutic potential of the filarial nematode secreted product, ES62 / William Harnett and Margaret M. Harnett -- Helminth-derived immunomodulatory molecules / Poom Adisakwattana ... [et al.] -- Fungal-derived immune modulating molecules / Tania C. Sorrell and Sharon C.A. Chen -- The immunosuppresive tick salivary protein, Salp15 / Ignacio J. Juncadella and Juan Anguita -- The serpin saga; development of a new class of virus derived anti-inflammatory protein immunotherapeutics / Alexandra Lucas ... [et al.] -- Helminthic therapy : using worms to treat immune-mediated disease / David E. Elliott and Joel V. Weinstock -- Chemokine binding proteins encoded by pathogens / Antonio Alcami and Margarida Saraiva.

Introduction -- Natural ecology and survival in water of mycobacteria of potential public health significance -- Environmental sources of Mycobacterium avium linked to routes of exposure -- Biology of waterborne pathogenic mycobacteria -- Analytical methods for the detection of waterborne and environmental pathogenic mycobacteria -- The Mycobacterium avium subspecies paratuberculosis problem and its relation to the causation of Crohn disease -- Disseminated infection, cervical adenitis and other MAC infections -- Skin, bone and soft tissue infections -- Pulmonary infection in non-HIV infected individuals -- Disease resulting from contaminated equipment and invasive procedures -- Control, treatment and disinfection of Mycobacterium avium complex in drinking water -- Approaches to risk management in priority setting -- References -- Index.

'Each book in the ... series offers a visually-integrated approach to review and is packaged with a CD-ROM, which serves as practice for the USMLE Step 1." -p.vii Preface.

Ch. 1. Enteroviruses -- Ch. 2. Rhinoviruses -- Ch. 3. Influenza viruses -- Ch. 4. Parainfluenza viruses -- Ch. 5. Respiratory syncytial virus (RSV) -- Ch. 6. Herpesviruses: general principles -- Ch. 7. Herpes simplex virus (HSV) types 1 and 2 -- Ch. 8. Cytomegalovirus -- Ch. 9. Epstein-Barr virus (EBV) -- Ch. 10. Varicella-Zoster virus (VZV) -- Ch. 11. Herpesvirus type 6 (HHV-6) -- Ch. 12. Kaposi sarcoma-associated herpesvirus (KSHV, HHV-8) -- Ch. 13. Herpesvirus simiae virus (Herpes B) -- Ch. 14. Adenoviruses -- Ch. 15. Retroviruses: general principles -- Ch. 16. Human immunodeficiency viruses -- Ch. 17. Human T cell leukemia/lymphoma viruses (HTLV-1 and -2) -- Ch. 18. Hepatitis viruses -- Ch. 19. Hemorrhagic fever viruses -- Ch. 20. Hantavirus pulmonary syndrome (HPS) -- Ch. 21. Papillomaviruses -- Ch. 22. Papovaviruses -- Ch. 23. Parvoviruses -- Ch. 24. Neurotropic arthropod-transmitted viruses -- Ch. 25. Rabieviruses -- Ch. 26. Poxviruses -- Ch. 27. Mumps -- Ch. 28. Rubellavirus -- Ch. 29. Rubeola (measles) -- Ch. 30. Transmissible spongiform encephalopathy -- Ch. 31. Lymphocytic choriomeningitis virus (LCMV) -- Ch. 32. Enteric viral disease.

Epidemiology of Mesothelioma -- Molecular Biology -- Serosal Anatomy and Anatomic Distribution of Mesothelioma -- Clinical Aspects of Mesothelioma -- Management of Malignant Serosal Effusions -- Pathologic Diagnosis and Classification of Mesothelioma -- Macroscopic Features of Mesotheliomas -- Classification and Histologic Features of Mesotheliomas -- Differential Diagnosis: Mesothelial Proliferations -- Differential Diagnosis: Other Mesothelial Lesions -- Differential Diagnosis: Nonmesothelial Lesions -- Differential Diagnosis: Nonmesothelial Tumors of the Serosal Cavity: Sarcomas -- Differential Diagnosis: Other Nonmesothelial Tumors.

Examination of the placenta -- Macroscopic features of the delivered placenta -- Microscopic survey -- Placental types -- Early development of the human placenta -- Basic structure of the villous trees -- Architecture of normal villous trees -- Characterization of the developmental stages -- Nonvillous parts and trophoblast invasion -- Involution of placental site; retained placenta -- Anatomy and pathology of the placental membranes -- Anatomy and pathology of the umbilical cord -- Placental shape aberrations -- Histopathologic approach to villous alterations -- Classification of villous maldevelopment -- Erythroblastosis fetalis and hydrops fetalis -- Transplacental hemorrhage, cell transfer, trauma -- Fetal storage disorders -- Maternal diseases complicating pregnancy: diabetes, tumors, preeclampsia, lupus anticoagulant -- Infectious diseases -- Abortion, placentas of trisomies, and immunologic considerations of recurrent reproductive failure -- Molar pregnancies -- Trophoblastic neoplasms -- Benign tumors and chorangiosis -- Multiple pregnancies -- Legal considerations -- Glossary -- Normative values and tables.

Appendix 1: Placental weight -- Appendix 2: Medicolegal aspects of placental pathology.Pathology of the placenta: an introduction and overview -- The development and structure of the placenta -- Physiology of the placenta -- Abnormalities of placentation and of placental development -- Macroscopoic abnormalities of the placenta -- Histological abnormalities of the placenta -- The placenta in pregnancies of abnormal duration -- The placenta in maternal disorders -- The placenta in abnormalities and disorders of the fetus -- The placenta in miscarriage -- Infections and inflammatory lesions of the placenta -- The placenta in multiple pregnancy -- Immunopatholgoy of the placenta -- Non-trophoblastic tumours of the placenta -- Gestational trophoblastic disease -- Pathology of the umbilical cord -- Pathology of the membranes -- Correlation of ultrasonic and pathological findings.

The criminalistics of controlled substances / Joseph P. Bono -- Overview of pathology of drug abuse : scene of death and the autopsy / Charles V. Wetli -- Heart disease / Renu Virmani, Allen P. Burke, Andrew Farb -- Vascular effects of substance abuse / Frank D. Kolodgie, Allen P. Burke, Jagat Narula, Florabel G. Mullick, Renu Virmani -- Myocardial alterations in drug abusers / Steven B. Karch -- Valvular heart disease / Michael D. Bell -- Lung disease / Michael D. Bell -- Disorders of the central nervous system / Michael D. Bell -- Toxicogenetics in drug abuse : pharmacogenomics for toxicology / Robert M. White, Steven H.Y. Wong -- Toxicogenetics in drug abuse : heritable channelopathies and myopathies / Kathryn A. Glatter, Jonica Calkins, Sanjay J. Ayirookuzhi.

The cell : structure, function, and molecular biology / Shankar Vallabhajosula, Seham Mustafa -- Pathophysiology and mechanisms of radiopharmaceutical localization / Shankar Vallabhajosula, Azu Owunwanne -- Basis of ¹⁸F-FDG positron emission tomography imaging / Seham Mustafa, Abbas Alavi, Abdelhamid H. Elgazzar -- Inflammation / Abdelhamid H. Elgazzar, Magda Elmonayeri -- Nuclear hematology / Kshitish C. Das -- Musculoskeletal system / Abdelhamid H. Elgazzar, Dia Shehab -- Thyroid gland / Salil D. Sarkar -- Parathyroid gland / Abdelhamid H. Elgazzar -- Adrenal gland / Sleiman Naddaf, Abdelhamid H. Elgazzar -- Basis of renal scintigraphy / Salil D. Sarkar, Pravin C. Singhal -- Basis of tumor imaging 1 : principles of tumor pathology and biology / Ezzeldin M. Ibrahim, Jaudah A. Al-Maghrabi -- Basis of tumor imaging 2 : scintigraphic and pathophysiologic correlation / Suman Jana, Hussein M. Abdel-Dayem -- Respiratory system / Abdelhamid H. Elgazzar, Moussa Khadada -- Basis of cardiac imaging 1: myocardial contractility and assessment of cardiac function / Sherif I. Heiba, Mohammad Zubaid -- Basis of cardiac imaging 2 : myocardial perfusion, metabolism, infarction, and receptor imaging in coronary artery disease and congestive heart failure / Josef Machac -- Digestive system 1 : gastrointestinal tract / Fuad Hassan, Eman Al-Enizi, Abdelhamid H. Elgazzar -- Digestive system 2 : liver and biliary tract / Chun K. Kim, Borys R. Krynyckyi, Josef Machac -- Basis and clinical application of brain imaging / James M. Mountz, Elmer C. San Pedro -- Basis of antibody imaging and therapy / Lionel S. Zuckier -- Lymphoscintigraphy / Arthur Z. Krasnow, Abdelhamid H. Elgazzar, Nafisah Kazem -- Basis of pediatric genitourinary imaging / Abdelhamid H. Elgazzar -- Basis of therapeutic nuclear medicine / Abdelhamid H. Elgazzar, Abdullatif Al-Bader -- Biological effects of ionizing radiation / Abdelhamid H. Elgazzar, Nafisah Kazem -- Glossary.

Basic cardiac structure and function / Vivek Iyer, Elazer R. Edelman, and Leonard S. Lilly -- The cardiac cycle: mechanisms of heart sounds and murmurs / Nicole Martin and Leonard S. Lilly -- Diagnostic imaging and catheterization / Nicole Martin and Patricia Challender Come -- The electrocardiogram / Lilit Garibyan and Leonard S. Lilly -- Atherosclerosis / James L. Young and Peter Libby -- Ischemic heart disease / Haley Naik, Marc S. Sabatine, and Leonard S. Lilly -- Acute coronary syndromes / Haley Naik, Marc S. Sabatine, and Leonard S. Lilly -- Valvular heart disease / Mia M. Edwards, Patrick T. O'Gara, and Leonard S. Lilly -- Heart failure / Ravi Vikram Shah and Michael A. Fifer -- The cardiomyopathies / Marc N. Wein, G. William Dec, and Leonard S. Lilly -- Mechanisms of cardiac arrhythmias / Hillary K. Rolls ... [et al.] -- Clinical aspects of cardiac arrhythmias / Hillary K. Rolls, William G. Stevenson, and Leonard S. Lilly -- Hypertension / Payman Zamani, Gordon H. Williams, and Leonard S. Lilly -- Diseases of the pericardium / Yanerys Ramos and Leonard S. Lilly -- Diseases of the peripheral vasculature / Arash Mostaghimi and Mark A. Creager -- Congenital heart disease / Vijay G. Sankaran and David W. Brown -- Cardiovascular drugs / Martin W. Schoen ... [et al.].

Basic cardiac structure and function / Ken Young Lin ... [et al.] -- The cardiac cycle : mechanisms of heart sounds and murmurs / Henry Jung and Leonard S. Lilly -- Cardiac imaging and catheterization / Henry Jung, Ken Young Lin, and Patricia Challender Come -- The electrocardiogram / Stephen R. Pomedli and Leonard S. Lilly -- Atherosclerosis / Jordan B. Strom and Peter Libby -- Ischemic heart disease / June-Wha Rhee, Marc S. Sabatine, and Leonard S. Lilly -- Acute coronary syndromes / June-Wha Rhee, Marc S. Sabatine, and Leonard S. Lilly -- Valvular heart disease / Christopher A. Miller, Patrick T. O'Gara, and Leonard S. Lilly --Heart failure / Neal Anjan Chatterjee and Michael A. Fifer -- The cardiomyopathies / Christopher T. Lee, G. William Dec, and Leonard S. Lilly -- Mechanisms of cardiac arrhythmias / Ranliang Hu ... [et al.] -- Clinical aspects of cardiac arrhythmias / Ranliang Hu, William G. Stevenson, and Leonard S. Lilly -- Hypertension / Christopher T. Lee, Gordon H. Williams, and Leonard S. Lilly -- Diseases of the pericardium / Yin Ren and Leonard S. Lilly -- Diseases of the peripheral vasculature / Fan Liang and Mark A. Creager -- Congenital heart disease / David D. Berg and David W. Brown -- Cardiovascular drugs / Cyrus K. Yamin ... [et al.].

1. Pulmonary, ob/gyn, ent, hem/onc -- 2. GI, neurology, rheumatology, endocrinology -- 3. CVS, dermatology, GU, general surgery.

I. Pulmonary, ob/gyn, ENT, hem/onc -- II. GI, neurology, rheumatology, endocrinology -- III. CV, dermatology, GU, orthopedics, general surgery, peds.

"But doctor, it takes three tests to find the bottom" -- This better not be serious-I've got a plane to catch -- Whew! the tests are negative, and I've got a plane to catch -- Taking my lumps: biopsy blues -- "Once per lethal disease": coping with chemo -- "How can you know I'm in remission?" -- What's so special about fifty-five? -- Graduation to the bone marrow unit -- "Zap it to me": staring into a Hiroshima-dose of radiation -- Hospital arrest -- My re-birthday -- How much risk is too much? -- Can't I stay another day? -- Darth Vader in pink -- A delicate balance -- Size matters -- In cancer, perfect is important -- "I think your kidneys did you a favor" -- A successful partnership -- You and your docs: allies, not adversaries.

Executive summary -- 1. Introduction -- 2. Components of a national health information infrastructure -- 3. Federal leadership and public-private partnerships -- 4. Health care data standards -- 5. Comprehensive patient safety programs in health care settings -- 6. Adverse event analysis -- 7. Near miss analysis -- 8. Patient safety reporting systems and applications -- 9. Standardized reporting.

"With coverage ranging from the influence of professional identity in medicine and problematic nature of "human error", to the psychological and social features that characterize healthcare work, to the safety-critical aspects of interfaces and automation, this book spans the width of the human factors field and its importance for patient safety today. In addition, the book discusses topics such as accountability, just culture, and secondary victimization in the aftermath of adverse events and takes readers to the leading edge of human factors research today: complexity, systems thinking and resilience"--Provided by publisher.

"Each year a vast sum of money is spent on health care around the globe and patient safety has become a serious global public health issue. Filled with up-to-date information, this book demonstrates how to handle patient safety-related problems by using methods developed in the area of engineering. It contains a chapter on mathematical concepts and another chapter on introductory material on safety and human factors considered essential to understand materials presented in subsequent chapters. The author's presentation covers topics in such a manner that readers will require no previous knowledge to understand the concepts"--Provided by publisher.

Integrating State-of-the-Art Computational Modeling with Clinical Practice: The Promise of Numerical Methods / David E. Krummen, Gainyu Oshodi and Sanjiv M. Narayan -- Patient-Specific Modeling of Cardiovascular Dynamics with a Major Role for Adaptation / Theo Arts, Joost Lumens, Wilco Kroon, Dirk Donker and Frits Prinzen, et al. -- Patient-Specific Modeling of Structure and Function of Cardiac Cells / Frank B. Sachse -- Studies of Therapeutic Strategies for Atrial Fibrillation Based on a Biophysical Model of the Human Atria / Laurent Uldry, Nathalie Virag, Jean-Marc Vesin and Lukas Kappenberger -- Patient-Specific Modeling for Critical Care / Maxwell Lewis Neal -- Biomechanical Analysis of Abdominal Aortic Aneurysms / Lambert Speelman, Mariëlle Bosboom, Geert W. H. Schurink and Frans N. v.d. Vosse -- The Cardiac Atlas Project: Towards a Map of the Heart / Michael Backhaus, Jae Do Chung, Brett R. Cowan, Carissa G. Fonseca and Wenchao Tao, et al. -- In Vivo Myocardial Material Properties and Stress Distributions in Normal and Failing Human Hearts / Jonathan F. Wenk, Zhihong Zhang, Guangming Cheng, Kay Sun and Joseph C. Walker, et al. -- Modeling of Whole-Heart Electrophysiology and Mechanics: Toward Patient-Specific Simulations / Fijoy Vadakkumpadan, Viatcheslav Gurev, Jason Constantino, Hermenegild Arevalo and Natalia Trayanova -- Personalized Computational Models of the Heart for Cardiac Resynchronization Therapy / Maxime Sermesant and Reza Razavi -- Patient-Specific Modeling of Hypoxic Response and Microvasculature Dynamics / Joanna Nathan and Amina Ann Qutub -- A Computational Framework for Patient-Specific Multi-Scale Cardiac Modeling / Jazmin Aguado-Sierra, Roy C. P. Kerckhoffs, Fred Lionetti, Darlene Hunt and Chris Villongco, et al.

Handling of the lymph node biopsy -- Immunohistology and other diagnostic techniques -- Anatomical and functional components -- Nodular lymphoid infiltrates -- Diffuse lymphoid infiltrations -- Defining microscopic features -- Nodal involvement by leukemias and extranodal lymphomas -- Needle core biopsies and aspirates.

Multiscale data condensation -- Unsupervised feature selection -- Active learning using support vector machine -- Rough-fuzzy case generation -- Rough-fuzzy clustering -- Rough self-organizing map -- Classification, rule generation and evaluation using modular rough-fuzzy MLP.

Review of immunology -- Immunology of IgE-mediated and other hypersensitivity responses -- Biochemical mediators of allergic reactions -- Evaluation and management of immune deficiency in allergy practice -- Evaluation of eosinophilia -- Allergens and other factors important in atopic disease -- Airborne pollen prevalence in the United States -- Diagnosis of immediate hypersensitivity -- Physiologic and biologic evaluation of allergic lung diseases -- Radiologic evaluation of allergic and related diseases of the upper airway -- Radiologic evaluation of allergic and related diseases of the lower airway -- Chronic rhinosinusitis role of rhinoscopy and surgery -- Principles of immunologic management of allergic diseases due to extrinsic antigens -- Anaphylaxis -- Allergy to stinging insects -- Erythema multiforme, Stevens-Johnson Syndrome, and toxic epidermal necrolysis -- Drug allergy -- Food allergies -- Asthma -- The infant and toddler with asthma -- Management of acute severe asthma -- Asthma clinical trials -- Hypersensitivity pneumonitis -- Allergic bronchopulmonary aspergillosis -- Occupational immunlogic lung disease -- Allergic rhinitis -- Nasal polyposis, sinusitis, and nonallergic rhinitis -- Allergic diseases of the eye and ear -- Atopic dermatitis -- Contact dermatitis -- Urticaria, angioedema, and hereditary angioedema -- Approach to the patient with pruritus -- Antihistamines -- β [beta] agonists -- Corticosteroids in treatment of allergic diseases -- Other antiallergic drugs: cromolyn, nedocromil, antileukotrienes, anticholinergics, and theophylline -- Delivery devices for inhaled medications -- Novel immunologic therapies -- Allergic disorders and pregnancy -- Eosinophilic esophagitis -- Chronic cough -- Sleep disorders in the allergic patient -- Management of the psychologically complicated patient -- Controversial and unproved methods in allergy diagnosis and treatment.

Part 1. PCR Fundamentals -- Part 2. Clinical Aspects and Diagnosis of Infectious Disease -- Part 3. PCR Protocols for Bacterial Pathogens -- Part 4. PCR Protocols for Viral Pathogens -- Part 5. PCR Protocols for Fungal and Parasitic Pathogens -- Part 6. Susceptibility Screening.

Conformation-Sensitive Capillary Electrophoresis / Emma Jane Ashton -- Conformation Sensitive Gel Electrophoresis / Marian Hill -- Denaturing HPLC for Mutation Screening / Mike Mitchell, Jacqueline Cutler -- In Situ Detection of Human Papillomavirus DNA After PCR-Amplification / Gerard J. Nuovo -- LATE-PCR and Allied Technologies: Real-Time Detection Strategies for Rapid, Reliable Diagnosis from Single Cells / Kenneth E. Pierce, Lawrence J. Wangh -- Long-PCR Amplification of Human Genomic DNA / Stephen Keeney -- Human Papilloma Virus Strain Detection Utilising Custom-Designed Oligonucleotide Microarrays / Duncan Ayers, Mark Platt, Farzad Javad, Philip J. Day -- Multiplex Ligation-Dependent Probe Amplification (MLPA®) for the Detection of Copy Number Variation in Genomic Sequences / Petra G. Os, Jan P. Schouten -- Screening for Genomic Rearrangements by Multiplex PCR/Liquid Chromatography / Claude Houdayer, Catherine Dehainault, Marion Gauthier-Villars, Dominique Stoppa-Lyonnet -- Mutation Surveyor: Software for DNA Sequence Analysis / Jayne A. Minton, Sarah E. Flanagan, Sian Ellard -- Non-invasive Prenatal Diagnosis / Cathy Meaney, Gail Norbury -- Automated DNA Sequencing / Yvonne Wallis, Natalie Morrell -- Phylogenetic Microarrays for Cultivation-Independent Identification and Metabolic Characterization of Microorganisms in Complex Samples / Alexander Loy, Michael Pester, Doris Steger -- Prenatal Detection of Chromosome Aneuploidy by Quantitative-Fluorescence PCR / Kathy Mann, Erwin Petek, Barbara Pertl -- Use of Robotics in High-Throughput DNA Sequencing / Stephen Keeney -- Detection of Factor V Leiden and Prothrombin c.20210G>A Allele by Roche Diagnostics LightCycler® / Peter C. Cooper -- RT-PCR for the Detection of Translocations in Bone and Soft Tissue Tumours in Formalin-Fixed Paraffin-Embedded Tissues / Ann Williams, D. Chas Mangham -- Detection of Minimal Residual Disease in Leukaemia by RT-PCR / Joanne Mason, Mike Griffiths -- Mutation Detection by Southern Blotting / Gillian Mellars, Keith Gomez.

Setup of a PCR Laboratory / Zaheer Khan -- Long-Range PCR with a DNA Polymerase Fusion / Holly H. Hogrefe, Michael C. Borns -- Isolation of Genomic Insertion Sites of Proviruses Using Splinkerette-PCR-Based Procedures / Bin Yin -- Lariat-Dependent Nested PCR for Flanking Sequence Determination / Daniel J. Park -- CODEHOP PCR and CODEHOP PCR Primer Design / Jeannette P. Staheli, Richard Boyce, Dina Kovarik, Timothy M. Rose -- Sequencing of Difficult DNA Regions by SAM Sequencing / Keith R. Mitchelson -- A Global Single-Cell cDNA Amplification Method for Quantitative Microarray Analysis / Kazuki Kurimoto, Mitinori Saitou -- Quantitation of MicroRNAs by Real-Time RT-qPCR / Caifu Chen, Ruoying Tan, Linda Wong, Richard Fekete, Jason Halsey -- High-Throughput SuperSAGE / Hideo Matsumura, Kentaro Yoshida, Shujun Luo, Detlev H. Krüger, Günter Kahl, Gary P. Schroth, Ryohei Terauchi -- Deep Cap Analysis of Gene Expression / Junpei Kurosawa, Hiromi Nishiyori, Yoshihide Hayashizaki -- Linking Emulsion PCR Haplotype Analysis / James G. Wetmur, Jia Chen -- PAP-LMPCR: An Improved, Sequence-Selective Method for the In Vivo Analysis of Transcription Factor Occupancy and Chromatin Fine Structure / Richard Ingram, Arthur Riggs, Constanze Bonifer -- The Many Faces of MLPA / Thomas Ohnesorg, Erin Turbitt, Stefan J. White -- Assessing Gene-Specific Methylation Using HRM-Based Analysis / Ee Ming Wong, Alexander Dobrovic -- Alu PCR / Maurizio Cardelli -- Asynchronous PCR / Caifu Chen, David Ruff, Jason Halsey -- Novel Applications of PCR Through the Use of DNA Substrates / Stuart M. Wilson -- Enhanced Solid Phase PCR for Increased Loading of Amplicon onto Solid Support / Daniel J. Park -- Application of Blocking Oligonucleotides to Improve Signal-to-Noise Ratio in a PCR / Hege Vestheim, Bruce E. Deagle, Simon N. Jarman -- Asymmetric Overlap Extension PCR Method for Site-Directed Mutagenesis / Yue-Hua Xiao, Yan Pei -- Ribosome Display: A Technology for Selecting and Evolving Proteins from Large Libraries / Birgit Dreier, Andreas Plückthun -- GLOBE: Analysis of DNA-Protein Interaction Analysis / Takaaki Kojima, Hideo Nakano -- PCR DNA-Array Profiling of DNA-Binding Transcription Factor Activities in Adult Mouse Tissues / Yimin Sun, Jing Cheng, Keith R. Mitchelson -- Nucleotide Exchange and Excision Technology DNA Shuffling and Directed Evolution / Janina Speck, Sabine C. Stebel, Katja M. Arndt, Kristian M. Müller.

Optic Nerve: The Glaucomatous Optic Nerve -- Optic Nerve: Clinical Examination -- Optic Nerve: Heidelberg Retinal Tomography -- Optic Nerve: Scanning Laser Polarimetry -- Optic Nerve: Optical Coherence Tomography -- Optic Nerve: Comparison of Technologies -- Optic Nerve: Atypical Nerves and Nerve Findings -- IOP: The Importance of Intraocular Pressure -- IOP: Instruments to Measure IOP -- IOP: Central Corneal Thickness -- IOP: Corneal Hysteresis -- IOP: Target Pressures -- IOP: Fluctuation -- Gonioscopy: Why Do Indentation? -- Visual Fields: Visual Field Test Strategies -- Visual Fields: Fluctuation and Progression -- Visual Fields: Field Interpretation -- Other Tests in Glaucoma: Genetic Testing -- Other Testing in Glaucoma: Optic Nerve Blood Flow I -- Other Tests in Glaucoma: Optic Nerve Blood Flow II -- Other Tests in Glaucoma: Multifocal Visual Evoked Potential -- Risk Factors -- Risk Factors: The Risk Calculator - Medical Treatment: First Line Agents and Monotherapy -- Medical Treatment: The Pregnant and Nursing Woman -- Medical Treatment: Carbonic Anhydrase Inhibitors -- Medical Treatment: Osmotic Agents -- Medical Treatment: Neuroprotection -- Medical Treatment: Treated vs. Untreated Glaucoma and Ocular Hypertension -- Medical Treatment: Adherence and Persistence -- Medical Treatment: Alternative Medicine and Glaucoma -- Procedural Treatments: Laser Trabeculoplasty -- Procedural Treatments: Endoscopic Cyclophotocoagulation -- Procedural Treatments: Transcleral Cyclophotocoagulation -- Procedural Treatments: Trabeculectomy -- Procedural Treatments: Perioperative Medication -- Procedural Treatments: Bleb Needling -- Procedural Treatments: Glaucoma Drainage Devices -- Procedural Treatments: New Surgical Options -- Procedural Treatments: Ex-PRESS Mini Glaucoma Shunt -- Procedural Treatments: Phacotrabeculectomy -- Procedural Treatments: Surgery in End-Stage Glaucoma -- Glaucomas: Managing Normal-Tension Glaucoma -- Glaucomas: Pseudoexfoliation Glaucoma -- Glaucomas: Pigment Dispersion Glaucoma and Angle Recession Glaucoma -- Glaucomas: Sturge Weber Syndrome -- Glaucomas: Glaucoma and the Cornea -- Glaucomas: Uveitic Glaucoma -- Glaucomas: Neovascular Glaucoma -- Pediatric Glaucoma: IOP, Axial Length, and Surgery Indications -- Pediatric Glaucoma: Glaucoma Medications and Steroids -- Pediatric Glaucoma: Angle Surgery and Glaucoma Drainage Devices -- Pediatric Glaucoma: Trabeculectomy and Glaucoma Drainage Devices -- Angle-Closure Glaucoma: Risk Factors -- Angle-Closure Glaucoma: Iridotomy -- Angle-Closure Glaucoma: Imaging -- Angle-Closure Glaucoma: Medical Therapy -- Angle-Closure Glaucoma: Surgical Management of Acute Angle-Closure Glaucoma -- Complications: Hypotony -- Complications: Bleb Leaks -- Complications: Blebitis.

The sound phenomena investigated / J. Hirschberg, T. Szende, P. Koltai -- Review of the literature. historical background / J. Hirschberg -- Patients / J. Hirschberg, P. Koltai, Z. Farkas -- Methods -- Characterization and acoustic description of the most commonly occurring sound signals / T. Szende, J. Hirschberg -- Airway and neurological diseases with pathological sounds.

Office evaluation of the child and adolescent -- Ambiguous genitalia in the newborn -- Vulvovaginal problems in the prepubertal child -- The physiology of puberty -- Precocious puberty -- Delayed puberty -- Amenorrhea in the adolescent -- Dysfunctional uterine bleeding -- Androgen abnormalities in the adolescent girl -- Structural abnormalities of the female reproductive tract -- Gynecologic pain : dysmenorrhea, accute and chronic pelvic pain, endometriosis, and premenstrual syndrome -- Education of the child and adolescent -- Pediatric urology in the pediatric and adolescent girl -- Vulvovaginal complaints in the adolescent -- Bacterial sexually transmitted infections : gonorrhea, chlamydia, pelvic inflammatory disease, and syphilis -- Human immunodeficiency virus in young women -- Human papillomavirus infection in children and adolescents -- Benign and malignant ovarian masses -- The breast : examination and lesions -- Contraception -- Teen pregnancy -- Adolescent sexuality -- Gynecologic issues in young women with chronic diseases -- Sexual abuse in the child and adolescent -- Complementary and alternative medicine for gynecology patients -- Legal issues in pediatric and adolescent gynecology.

1. Bone cell biology: osteoclasts, osteoblasts, osteocytes / Katharine Jähn and Lynda F. Bonewald -- 2. Bone matrix and mineralization / Marc D. McKee and William G. Cole -- 3. Prenatal bone development / Fanxin Long -- 4. Postnatal bone growth: growth plate biology, bone formation, and remodeling / Christa Maes and Henry M. Kronenberg -- 5. Dental development and maturation, from the dental crypt to the final occlusion / Jean-Marc Retrouvey, Michel Goldberg and Stéphane Schwartz -- 6. Parathyroid hormone and calcium homeostasis / John T. Potts and Thomas J. gardella -- 7. Phosphate homeostasis regulatory mechanisms / Clemens Bergwitz and Harald Jüppner -- 8. Vitamin D biology / René St-Arnaud and Marie B. Demay -- 9. Peak bone mass and its regulation / Jean-Philippe Bonjour ... [et al.] -- 10. Pregnancy and lactation / Ann Prentice -- 11. Fetal mineral homeostasis / Christopher S. Kovacs -- 12. Radiology / Judith E. Adams ... [et al.] -- 13. Non-invasive techniques for bone mass measurement / Mary B. Leonard and Laura K. Bachrach -- 14. Assessment of maturation: bone age and pubertal assessment / Noël Cameron and David D. Martin --15. Biochemical markers of bone metabolism / Nick Shaw and Wolfgang Högler -- 16. Pediatric bone histomorphometry / frank Rauch -- 17. A diagnostic approach to skeletal dysplasias / Sheila Unger, Andrea Superti-Furga and David L. Rimoin -- 18. The spectrum of pediatric osteoporosis / Maria Luisa Bianchi and Francis H. Glorieux -- 19. Osteogenesis imperfecta / Francis H. Glorieux and David Rowe -- 20. Sclerosing bone dysplasias / Bram Perdu ... [et al.] -- 21. Parathyroid disorders / Murat Bastepe, Harald Jüppner and Rajesh V. Thakker -- 22. Fibrous dysplasia / Paolo Bianco and Shlomo Wientroub -- 23. Nutritional rickets / John M. Pettifor -- 24. Metabolic bone disease in the neonatal period and its later sequelae / Nick Bishop, Mary Pewtrell and Nick Harvey -- 25. Rickets due to hereditary abnormalities of vitamin D synthesis or action / Anthony A. Portale, Farzana Perwad and Walter L. Miller -- 26. Familial hypophosphatemia and related disorders / Ingrid A. Holm, Michael J. Econs and Thomas O. Carpenter --27. Hereditary tubular disorders of mineral handling / Daniella Magen and Israel Zelikovic -- 28. Hypophosphatasia / michael P. Whyte -- 29. Chronic kidney disease mineral and bone disorder / Katherine Wesseling Perry and Isidro B. Salusky -- 30. Extraskeletal bone formation / Eileen M. Shore and Frederick S. Kaplan.

Anesthetic and peroperative management / Monica A. Stokes -- Monitoring of the pediatric cardiac patient / Carol L. Lake and Harvey L. Edmonds -- Physiology and techniques of extracorporeal circulation in the pediatric patient / James A. DiNardo -- Profound hypothermia and circulatory arrest / James A. DiNardo -- Vital organ preservation during surgery for congenital heart disease / Emad B. Mossad and Ibrahim Farid -- Management of postbypass myocardial dysfunction / Laurie K. Davies -- Hemostasis, coagulation, and transfusion in the pediatric cardiac patient / William C. Oliver, Jr. -- Management of postbypass pulmonary hypertension and respiratory dysfunction / Angus McEwan -- -- Septal and endocardial cushion defects / Julie K. Hudson and Jayant K. Deshpande -- Tetralogy of Fallot / William A. Lell and F. Bennett Pearce -- Transposition of the great vessels / James A. DiNardo --Anomalies of the aortic arch and valve / David A. Rosen and Kathleen R. Rosen -- Anomalies of the pulmonary valve and right ventricular outflow tract / Ian Adatia and Helen Holtby -- Tricuspid atresia / Susan Tebich -- Hypoplastic left heart syndrome / George M. Hoffman and Eckehard A.E. Stuth -- Double-outlet right ventricle / Julie K. Hudson and Jayant K. Deshpande -- Truncus arteriosus / Ian M. McKenzie -- Anomalies of systemic and pulmonary venous return / Carol L. Lake -- Abnormalities of the atrioventricular valves / Victor C. Baum -- Coronary artery anomalies / Monica A. Stokes -- Cardiomyopathies / Ian M. McKenzie and Robert G. Weintraub -- Pulmonary hypertension, persistent fetal circulation, and Eisenmenger Syndrome / Paul B. Baines and Andrew Selby -- Pediatric cardiac and lung transplantation / Linda J. Mason ... [et al.] -- Secondary vascular anomalies and cardiac tumors / Steven M. Auden -- Anesthesia for noncardiac surgery in children and adults with congenital heart disease / David Frankville --History of pediatric cardiac anesthesia / Carol L. Lake -- Pediatric heart disease in the developing world / Annette J.M. Davis -- -- Intrauterine development of the cardiovascular system / Carol L. Lake -- Extrauterine development of the cardiovascular system / Peter D. Booker -- Pediatric anesthesia pharmacology / D. Ryan Cook, Peter J. Davis, and Richard J. Ing -- -- Preoperative evaluation and preparation of the pediatric patient with cardiac disease / Ellise Delphin, Ali Inanc Seçkin, and Roger A. Moore -- Cardiac catheterization and other radiographic examinations / Ingrid Hollinger and Alexander Mittnacht -- Pediatric electrocardiography and cardiac electrophysiology / Kevin P. Walsh -- Pediatric echocardiography / Wyman W. Lai, H. Helen Ko, and Ira A. Parness --Postoperative care / Peter D. Booker -- Postoperative cardiovascular dysfunction: pharmacologic support / Peter D. Booker -- Postoperative respiratory function and its management / Lori A. Aronson and Catherine L. Dent -- Renal, gastrointestinal, hepatic, and neurologic dysfunction / Duncan J. Macrae -- Postoperative pain management in the pediatric cardiac patient / Andrew R. Wolf -- Anesthesia for cardiac procedures in the pediatric intensive care unit / Annette J.M. Davis -- -- Quality in pediatric cardiac anesthesia / D. Ryan Cook and Lisa Faberowski -- Teaching pediatric cardiac anesthesiology / Chris Chin and Alan Jay Schwartz.

Chest Ultrasound (US) / Goya Enriquez, Celestino Aso and Xavier Serres -- The Contribution of Nuclear Medicine to Pulmonary Imaging / Michael J. Gelfand and David L. Gilday -- Helical Multidetector Chest CT / Pilar García-Peña and Catherine M. Owens -- High-Resolution CT of the Lung in Children / Javier Lucaya and Hubert Ducou Le Pointe -- Pulmonary Malformations Beyond the Neonatal Period / Josep M. Mata and Amparo Castellote -- CT of Acute Pulmonary Disease: Infection, Infarction, and Trauma / Lane F. Donnelly -- Pediatric Tuberculosis / Pedro A. Daltro and Eloá Nunez-Santos -- How to Perform and Interpret MR Sleep Studies for Obstructive Sleep Apnea in Children / Lane F. Donnelly -- Foreign Body Aspiration: Imaging Aspects / Benjamin Z. Koplewitz and Jacob Bar-Ziv -- Imaging Evaluation of the Thymus and Thymic Disorders in Children / Donald P. Frush -- Lymphoma - Controversies in Imaging the Chest / Sue C. Kaste -- Chest Tumours Other than Lymphoma / Kieran McHugh -- Thoracic Manifestations of Systemic Diseases / Alan S. Brody -- Radiology of the Chest Wall / Georg F. Eich, Christian J. Kellenberger and Ulrich V. Willi -- Pediatric Cardiac MRI / Rajesh Krishnamurthy and Taylor Chung -- Pediatric Cardiac CT / Laureen Sena, Rajesh Krishnamurthy and Taylor Chung -- Fetal MRI of the Chest / Pedro A. Daltro and Heron Werner -- Neonatal Chest Imaging / Janet L. Strife and Eric J. Crotty.

Family interviewing and history-taking / Richard B. Goldbloom -- Skills for culturally sensitive care / Richard B. Goldbloom -- Assessing physical growth and nutrition / Richard B. Goldbloom -- Evaluating the newborn : diagnostic approach / Alexandra A. Howlett, Krista A. Jangaard -- Assessing congenital anomalies / Mark D. Ludman -- Developmental and behavioral assessment / Sarah E. Shea -- Examining the head and neck / D. Anna Jarvis -- Examining the visual system / G. Robert LaRoche -- Evaluating the respiratory system / Daniel M. Hughes -- Cardiovascular assessment of infants and children / Andrew E. Warren, Douglas L. Roy -- Evaluating gastrointestinal symptoms / Mohsin Rashid -- Surgical assessment of the abdomen / Michael Giacomantonio -- Neurological examination / Joseph M. Dooley -- Psychiatric assessment of children and adolescents / Harriet L. MacMillan, Jan Ellen Fleming, Ellen Jamieson -- Musculoskeletal examination / Bianca A. Lang -- Clinical endocrine evaluation / Elizabeth A. Cummings, Sonia R. Salisbury -- Approaching the adolescent / Alexa L. Bagnell -- Gynecological assessment / Joan B. Wenning -- Assessing the skin / Laura A. Finlayson -- Caring for children with chronic conditions and their families / Richard B. Goldbloom -- Clinical evaluation for possible child abuse / Steven Bellemare -- Assessing the appropriate role for children in health decisions / Nuala P. Kenny, Linda E. Skinner -- Palliative care / Gerri Frager, David LaPierre.

Respiratory system -- Cardiovascular system -- Central nervous system -- Infectious diseases -- Hematology and oncology -- Renal system -- Endocrine system -- Nutrition and the gastrointestinal system -- Immunology -- Metabolic disorders -- Pain management -- Pharmacology and toxicology -- Traumatology -- Statistics -- Ethics.

Fundamentals of Gas Exchange and the Assessment of Oxygenation and Ventilation /John S. Sullivan and Toah A. Nkromah --Oxygen Delivery and Oxygen Consumption in Pediatric Critical Care /Juan A. Gutierrez and Andreas A. Theodorou --Hemodynamics /Scott A. Hagen and Timothy E. Corden --Regional Circulations /Demetris Yannopoulos and Vinay M. Nadkarni --Assessment of Cardiovascular Function /Frank A. Maffei --Overview, Structure and Function of the Nephron /Megan Rashid and George J. Schwartz --Physiology of Skeletal Muscle and the Neuromuscular Junction /Ellen D. Iannoli and Michael P. Eaton --Assessment of Neurologic Function /Elizabeth E. Scarlett, Brandi N. Peachey and Jill M. Gotoff --Endothelial Interactions and Coagulation /Trung C. Nguyen and Joseph A. Carcillo --The Inflammatory Response /Mark W. Hall --Genetic Predisposition to Critical Illness in the Pediatric Intensive Care Unit /Neal J. Thomas, Mary K. Dahmer and Michael W. Quasney --Conventional Mechanical Ventilation /Joseph D. Tobias --Non-conventional Mechanical Ventilation /Michael D. Dettorre --Mechanical and Electrical Myocardial Support /Sabrina S. L. Tsao, Kendra M. Ward and Denise M. Goodman --Renal Replacement Therapies and Other Extracorporeal Therapies /Andrew L. Schwaderer and Marc B. Lande --Pharmacology /Gretchen L. Brummel and Steven E. Lucking --Cardiovascular Drug Therapy /Frank A. Maffei --Sedation and Analgesia /Richard L. Lambert, Lela W. Brink and Frank A. Maffei.Neuromuscular Blockade /Michael P. Eaton and A. Marika Stone --Use of Blood Products /Jill M. Cholette and Norma B. Lerner --Nutrition in Critical Illness /Margaret A. Satchell --Upper Airway Obstruction /Steven E. Lucking --Severe Asthma /Neal J. Thomas and Frank A. Maffei --Acute Respiratory Distress Syndrome /Frank A. Maffei and Neal J. Thomas --Acute Pulmonary Infections /Karen S. Powers --Circulatory Failure/Shock /Hector R. Wong --Sepsis /Angela Lorts, Timothy T. Cornell and Thomas P. Shanley --Multiple Organ Dysfunction Syndrome /Nikoleta S. Kolovos and Barry P. Markovitz --Disorders of Cardiac Rhythm /William G. Harmon --Post-operative Cardiac Care /Surender Rajasekaran and John C. Ring --Cerebral Resuscitation and Traumatic Brain Injury /Ericka L. Fink, Patrick M. Kochanek and Robert S. B. Clark --Neurological Diseases in Pediatric Critical Care Medicine /Michael J. Bell and Aditi Sharangpani --The Approach to the Critically Ill Infant /Frank A. Maffei --Nosocomial Infections /Elise W. van der Jagt --Fluid/Electrolyte/Acid-Base Abnormalities /Michael L. Moritz --Acute Kidney Injury /William S. Varade and Elif Erkan --Acute Liver Injury and Failure in Children /Richard L. Lambert --Hematology and Oncology in Critical Illness /Leonardo R. Brandão, Scott C. Howard, Kenneth W. Gow, Surender Rajasekaran and Robert F. Tamburro --Critical Care Endocrinology /Kecha A. LynShue and Mark A. Sperling --Metabolic Crises /Paul J. Bellino --Trauma/Burn /Robert E. Cilley and Eric H. Bradburn --Toxicology for the Pediatric Intensivist /L. Eugene Daugherty and Frank A. Maffei.

Volume 1 -- Basic science and principles of diagnosis and treatment -- Neonatal and inherited disorders -- Diseases of mucous membranes and appendageal structures -- Volume 2 -- Reaction patterns -- Neoplasms and systemic diseases -- Infections and infestations -- Injury and responses.

Aerobic fitness: what are we measuring? / N. Armstrong, J.R. Welsman -- Anaerobic fitness tests: what are we measuring? / E. Van Praagh -- Secular changes in pediatric aerobic fitness test performance: the global picture / G.R. Tomkinson, T.S. Olds -- Physical fitness of children and adolescents in the United States: status and secular change / R.M. Malina -- Fitness of Canadian children: range from traditional Inuit to sedentary city dwellers, and assessment of secular changes / R.J. Shephard -- Who are the Eurofittest? / G.R.Tomkinson, T.S. Olds, J. Borms -- Changes in Eurofit test performance of Estonian and Lithuanian children and adolescents (1992-2002) / T. Jürimäe ... [et al.] -- Evolution and variability in fitness test performance of Asian children and adolescents / D.J. Macfarlane, G.R.Tomkinson --Secular changes in aerobic fitness test performance of Australasian children and adolescents / G.R.Tomkinson, T.S. Olds -- Prevalence, trends, and environmental influences on child and youth physical activity -- J. Salmon, A. Timperio -- Evolution of maximal oxygen uptake in children / T.W. Rowland -- Distributional changes in the performance of Australian children on tests of cardiorespiratory endurance / J. Dollman, T.S. Olds -- Declines in aerobic fitness: are they only due to increasing fatness? / T.S. Olds, K. Ridley, G.R. Tomkinson.

Pathogenesis of inflammatory bowel disease / di Nardo, G., Cucchiara, S. -- Epidemiology in pediatric inflammatory bowel disease / Koletzko, S. -- Genetics of inflammatory bowel disease / Cooney, R., Jewell, D. -- Pathology of inflammatory bowel disease in children / Harpaz, N. -- Early-onset inflammatory bowel disease : infant, toddler, and pre-school / Lebenthal, E., Branski, D., Walker-Smith, J.A. -- Radiological and imaging features / Laghi, A. ... [et al.] -- Endoscopic modalities in pediatric inflammatory bowel disease / Venkatesh, K., Thomson, M. -- Approach to clinical diagnosis of inflammatory bowel disease / Bousvaros, A. -- Growth and puberty in inflammatory bowel disease / Savage, M.O., Mark Beattie, R., Sanderson, I.R.S. -- Treatment by enteral nutrition in inflammatory bowel disease / Köglmeier, J., Heuschkel, R. -- Medical therapy for inflammatory bowel disease in children and adolescents / Kappelman, M.D., Rufo, P.A. -- Surgical therapy / McCrudden Erickson, K., Teitelbaum, D.H., Coran, A.G. -- Transition to adult care / Hait, E.J. ... [et al.].

Shut-down interview and relationships -- Medical interview: the opening phase -- History of present illness -- Concluding phase -- Family -- Well-child visit -- Primary care and child mental health -- Sensitive topics: suicidality, child abuse -- Supporting families expressing grief while giving bad news -- Challenging patients -- Wandering interviews -- Using experiential techniques to teach interviewing skills -- Glossary of interviewing terms.

Introduction and historical background: pediatric Hodgkin lymphoma -- Biology and pathology of Hodgkin's disease -- Treatment of pediatric Hodgkin lymphoma -- Treatment of relapsed/refractory Hodgkin lymphoma -- Non-Hodgkin's lymphoma: introduction and historical background -- Biology and pathology of pediatric non-Hodgkin lymphoma -- B-cell lymphoma/ Burkitt lymphoma -- Anaplastic large-cell lymphoma -- Precursor B and precursor T-cell lymphoblastic lymphoma -- Cutaneous T-cell lymphomas and rare T-cell non-Hodgkin lymphomas -- Lymphoproliferative disorders related to immunodeficiencies -- Late effects following lymphoma treatment.

Why Should We Write a Book on Pediatric Metabolic Syndrome? Commentaries from Worldwide Experts /Arthur S. Agatston, Arthur S. Agatston, Arthur S. Agatston, Shari Barkin and Gerald S. Berenson, et al. --Epidemiology of the Metabolic Syndrome in Youth: A Population-to-Clinical-Based Perspective /Sarah E. Messiah, Kristopher L. Arheart and James D. Wilkinson --Perinatal Epidemiology of Metabolic Syndrome Risk Factors /Barbara Luke and Mary L. Hediger --Metabolic Syndrome in Childhood as a Risk Factor for Type 2 Diabetes /Nicola Santoro, Cosimo Giannini and Sonia Caprio --Effects of Metabolic Syndrome on Atherosclerosis in Childhood /Muhammad Yasir Qureshi, Sarah E. Messiah, Tracie L. Miller and Steven E. Lipshultz --Metabolic Syndrome and Associated Kidney Disease /Carolyn L. Abitbol and Wacharee Seeherunvong --Metabolic Syndrome and Related Liver Diseases /Aymin Delgado-Borrego.The Relationship Between Asthma, Sleep Apnea, and Other Respiratory Disorders and Childhood Metabolic Syndrome /Erick Forno and Annabelle Quizon --The Relationship Between Components of the Metabolic Syndrome and Bone Health /Zeina M. Nabhan and Linda A. DiMeglio --The Relationship of Childhood Obesity with Cardiomyopathy and Heart Failure /Muhammad Yasir Qureshi, James D. Wilkinson and Steven E. Lipshultz --Childhood Metabolic Syndrome and Cancer Risk /Stefanie R. Brown and Steven E. Lipshultz --Neurocognitive and Psychological Correlates of Metabolic Syndrome in Childhood /Anna Maria Patino-Fernandez, Amber Daigre and Alan M. Delamater --Genomics of Pediatric Metabolic Syndrome /Evadnie Rampersaud and Maria A. Ciliberti --Physical Activity Assessment and Intervention /Gabriel Somarriba --Nutritional Evaluation and Intervention /Runa Diwadkar Watkins, Daniela Neri and Tracie L. Miller --Pharmacological Therapies of Metabolic Syndrome /Adriana Carrillo-Iregui and Carley Gomez-Meade --Bariatric Surgery to Reverse Metabolic Syndrome in Adolescents /Noor Kassira, Valerie Ann Marks and Nestor de la Cruz-Muñoz --Moving Clinic- and Community-Based Practice into Policy to Address Child Healthy Weight (and Vice Versa) /Danielle Hollar, T. Lucas Hollar and Michelle A. Lombardo.

v. 1. Sections 1-6 -- v. 2. Sections 7-12.

Techniques and methods in pediatric neuroimaging -- Normal development of the neonatal and infant brain, skull, and spine -- Toxic and metabolic brain disorders -- Brain and spine injuries in infancy and childhood -- Congenital malformations of the brain and skull -- The phakomatoses -- Intracranial, orbital, and neck masses of childhood -- Hydrocephalus -- Congenital anomalies of the spine -- Neoplasms of the spine -- Infections of the nervous system -- Anomalies of cerebral vasculature: diagnostic and endovascular considerations.

Techniques and methods in pediatric neuroimaging / Christopher P. Hess and A. James Barkovich -- Normal development of the neonatal and infant brain, skull and, spine / A. James Barkovich and Pratik Mukherjee -- Metabolic, toxic, and inflammatory brain disorders / A. James Barkovich and Zoltan Patay -- Brain and spine injuries in infancy and childhood / Erin Simon Schwartz and Jim Barkovich -- Congenital malformations of the brain and skull / A. James Barkovich and Charles A. Raybaud -- The phakomatoses / Gilbert Vezina and A. James Barkovich -- Intracranial, orbital, and neck masses of childhood / Charles Raybaud and A. James Barkovich -- Hydrocephalus / A. Raybaud and A. James Barkovich -- Congenital anomalies of the spine / Erin Simon Schwartz and A. James Barkovich -- Neoplasms of the spine / A. James Barkovich -- Infections of the developing and mature nervous system / Gary Hedlund and A. James Barkovich -- Anomalies of cerebral vasculature: diagnostic and endovascular considerations / Philip M. Meyers, Van V. Halbach, and A. James Barkovich.

Suggestions for history and physical examination -- Headache -- School problems and attention-deficit hyperactivity disorder -- Abnormal movements -- Behavioral and sleep problems -- Seizures, epilepsy, and related disorders -- Dizziness, fainting, and loss of balance -- Delay or regression of motor development associated with low muscle tone -- Autism and language disorders -- Cerebral palsy (static encephalopathy) and related problems -- Abnormalities of cranial size and shape, hydrocephalus, and spinal dysraphism -- Common neurological complications of trauma -- Stroke, acute paraparesis, and other serious disorders of acute and subacute onset -- Other important neurological syndromes.

Dyslexia / Kytja K.S. Voeller -- Sleep disorders in children / Rafael Pelayo ... [et al.] -- Ischemic stroke in childhood / Peter E. Anderson and Gabrielle A. deVeber -- Neuropsychiatric aspects of blindness and severe visual impairment, and deafness and severe hearing loss in children / Bryan H. King, Peter C. Hauser, and Peter K. Isquith -- Movement disorders / Ergun Y. Uc and Robert L. Rodnitzky -- Epilepsy syndromes in childhood / Rochelle Caplan and Erin Lanphier --Prematurity and cerebral palsy / Agnes Whitaker ... [et al.] -- Traumatic brain injury / Sharon Arffa -- Spina bifida and hydrocephalus / Gregory S. Liptak -- Pediatric brain tumors / David L. Kaye and Patricia K. Duffner.Mental retardation / Suzanne T.P.V. Sundheim, Ruth Mize Myers, and Kytja K.S. Voeller -- Genetic syndromes / Chiara Pantaleoni ... [et al.] -- Neuropsychiatric aspects of autism spectrum disorders and childhood-onset schizophrenia / Natacha Akshoomoff -- Attention deficit-hyperactivity disorder / Kytja K.S. Voeller -- Conduct disorder and sociopathy / Markus J.P. Kruesi and Kevin Gray -- Pediatric mood disorders / Robert A. Kowatch ... [et al.] -- Anxiety disorders / Sanjeev Pathak and Bruce D. Perry -- Eating disorders / David C. Jimerson, Barbara E. Wolfe, and Silke Naab -- Substance use disorders / Oscar G. Bukstein and Ralph E. Tarter.Normal development of the nervous system / Harvey B. Sarnat and Laura Flores-Sarnat -- Normal childhood growth and development of intellect, language, temperament, emotion, and social skills / Marilyn Augustyn -- Clinical neuropsychiatric assessment of children and adolescents / Paul D. Larsen -- Neuropsychological and psychoeducational testing / Renée Lajiness-O'Neill and Isabelle Beaulieu -- Anatomic imaging of the developing human brain / Jay N. Giedd -- Functional imaging of the developing human brain / Harry T. Chugani and Csaba Juhász -- Clinical electrophysiology of the developing human brain / Leslie J. Carver and Martha Ann Bell.Pediatric psychopharmacology / Daniel A. Geller, Paul Hammerness, and Thomas Spencer -- Electroconvulsive therapy in pediatric neuropsychiatry / C. Edward Coffey -- Genetic evaluation, counseling, and treatment / Carol E. Anderson -- Psychological and behavioral interventions / Robert T. Ammerman and Mariah E. Coe -- Psychoeducational interventions in pediatric neuropsychiatry / Jeffrey A. Miller ... [et al.] -- Selected legal issues / Peter S. Latham and Patricia H. Latham.

v. 1. Brain -- v. 2. Head and neck, spine.

Introduction / S.T. Treves -- Central nervous system: pt. 1, Brain / S.T. Treves, Harry T. Chugani, Blaise F.D. Bourgeois ; pt. 2, Cerebrospinal fluid / S.T. Treves, Alvin Kuruc -- Thyroid / Stephen A. Huang -- Calculation of administered doses of iodine 131 in the treatment of thyroid disease / Robert E. Zimmerman -- Lungs / S.T. Treves, Alan B. Packard -- Cardiovascular system / S.T. Treves, Elizabeth D. Blume, Laurie Armsby, Jane W. Newburger, Alvin Kuruc -- Gastroesophageal reflux, gastric emptying, esophageal transit, and pulmonary aspiration / Zvi Bar-Sever -- Gastrointestinal bleeding / S.T. Treves, Richard J. Grand -- Liver and spleen / S.T. Treves, A.G. Jones -- Kidneys / S.T. Treves, William E. Harmon, Alan B. Packard, Alvin Kuruc -- Vesicoureteral reflux / S.T. Treves, Ulrich V. Willi -- Calculation of glomerular filtration rate / Robert E. Zimmerman, Karl Mitchell, Royal T. Davis -- Bone / Leonard P. Connolly, Laura A. Drubach, Susan A. Connolly, S.T. Treves -- Pediatric oncology / Hossein Jadvar, Barry L. Shulkin -- Infection and inflammation / Christopher J. Palestro, Charito Love, Maria B. Tomas -- Magnification / Royal T. Davis, Robert E. Zimmerman, S.T. Treves -- Single positron emission computed tomography / Frederic H. Fahey, Beth A. Harkness -- Positron emission tomography / Frederic H. Fahey, Ramsey D. Badawi -- Radiation risk / S. James Adelstein -- Internal dosimetry / Michael G. Stabin.

Chapter 1. Overview of pediatric nursing -- Chapter 2. Legal and ethical issues -- Chapter 3. The child in context of the family -- Chapter 4. Community and home health nursing -- Chapter 5. School Nursing -- Chapter 6. Theoretical approaches to the growth and development of children -- Chapter 7. Growth and development of the newborn -- Chapter 8. Growth and development of the infant -- Chapter 9. Growth and development of the toddler -- Chapter 10. Growth and development of the preschooler -- Chapter 11. Growth and development of the school-age child -- Chapter 12. Growth and development of the adolescent -- Chapter 13. Child and family communication -- Chapter 14. Pediatric assessment -- Chapter 15. Infectious Diseases -- Chapter 16. Care of children who are hospitalized -- Chapter 17. Chronic conditions -- Chapter 18. Pain management -- Chapter 19. Medication administration -- Chapter 20. Loss and bereavement -- Chapter 21. Fluid and electrolyte alterations -- Chapter 22. Genitourinary alterations -- Chapter 23. Gastrointestinal alterations -- Chapter 24. Respiratory alterations -- Chapter 25. Cardiovascular alterations -- Chapter 26. Hematological alterations -- Chapter 27. Immunologic alterations -- Chapter 28. Endocrine alterations -- Chapter 29. Cellular alterations -- Chapter 30. Integumentary alterations -- Chapter 31. Sensory alterations -- Chapter 32. Neurological alterations -- Chapter 33. Cognitive alterations -- Chapter 34. Musculoskeletal alterations -- Chapter 35. Psychosocial alterations -- Chapter 36. Child abuse and neglect.

Chapter 1. Overview of pediatric nursing -- Chapter 2. Legal and ethical issues -- Chapter 3. The child in context of the family -- Chapter 4. Community and home health nursing -- Chapter 5. School Nursing -- Chapter 6. Theoretical approaches to the growth and development of children -- Chapter 7. Growth and development of the newborn -- Chapter 8. Growth and development of the infant -- Chapter 9. Growth and development of the toddler -- Chapter 10. Growth and development of the preschooler -- Chapter 11. Growth and development of the school-age child -- Chapter 12. Growth and development of the adolescent -- Chapter 13. Child and family communication -- Chapter 14. Pediatric assessment -- Chapter 15. Infectious Diseases -- Chapter 16. Care of children who are hospitalized -- Chapter 17. Chronic conditions -- Chapter 18. Pain management -- Chapter 19. Medication administration -- Chapter 20. Loss and bereavement -- Chapter 21. Fluid and electrolyte alterations -- Chapter 22. Genitourinary alterations -- Chapter 23. Gastrointestinal alterations -- Chapter 24. Respiratory alterations -- Chapter 25. Cardiovascular alterations -- Chapter 26. Hematological alterations -- Chapter 27. Immunologic alterations -- Chapter 28. Endocrine alterations -- Chapter 29. Cellular alterations -- Chapter 30. Integumentary alterations -- Chapter 31. Sensory alterations -- Chapter 32. Neurological alterations -- Chapter 33. Cognitive alterations -- Chapter 34. Musculoskeletal alterations -- Chapter 35. Psychosocial alterations -- Chapter 36. Child abuse and neglect.

Acute Leukemia / Michael E. Rytting, Mary S. Choroszy, Demetrios Petropoulos and Ka Wah Chan -- Hodgkin Lymphoma and Non-Hodgkin Lymphoma / Ka Wah Chan, Demetrios Petropoulos, Eric L. Chang and Michael E. Rytting -- Brain Tumors: Diagnosis, Surgery and Radiotherapy, and Supportive Care / Joann L. Ater, Jeffrey S. Weinberg, Moshe H. Maor, Bartlett D. Moore and Donna R. Copeland -- Brain Tumors: Chemotherapy and Investigational Therapy / Joann L. Ater, Jeffrey S. Weinberg, Moshe H. Maor and Demetrios Petropoulos -- Wilms' Tumor / Norman Jaffe and Margaret G. Pearson -- Neuroblastoma / Joann L. Ater and Laura L. Worth -- Soft-Tissue Tumors / R. Beverly Raney, Richard J. Andrassy, Martin Blakely, Tina V. Fanning and Moshe H. Maor, et al. -- Osteosarcoma / Norman Jaffe and Margaret G. Pearson -- Ewing's Sarcoma / Cynthia E. Herzog, Anita Mahajan and Valerae O. Lewis -- Retinoblastoma / Misha Faustina, Cynthia E. Herzog and Dan S. Gombos -- Differentiated Thyroid Cancer / Rena Vassilopoulou-Sellin -- Medullary Thyroid Carcinoma / Robert F. Gagel -- Melanoma / Cynthia E. Herzog, Hafeez Diwan, Merrick I. Ross and Victor G. Prieto -- Novel Therapeutic Approaches / Sima S. Jeha and Laura L. Worth -- Supportive Care: Myelosuppression / Nidra I. Rodriguez Cruz, Renee M. Madden and Craig A. Mullen -- Supportive Care: Symptom Control / Renee M. Madden, Susannah E. Koontz-Webb, Donna S. Zhukovsky and Craig A. Mullen -- Behavioral Medicine in Cancer Care / Donna R. Copeland and Martha A. Askins -- The Adolescent and Young Adult Program / Sima S. Jeha and Martha A. Askins.

General aspects of childhood leukemia -- Acute lymphoblastic leukemia -- Acute myelogenous leukemia -- Myelodysplastic syndrome -- Myeloproliferative syndromes (chronic myeloproliferative disorders) -- Non-Hodgkin lymphoma -- Hodgkin disease -- Histiocytoses -- Brain tumors -- Neuroblastoma -- Nephroblastoma (Wilms tumor) -- Soft tissue sarcoma -- Osteosarcoma -- Ewing sarcoma family of tumors -- Retinoblastoma -- Germ cell tumors -- Hepatic tumors -- Emergencies in pediatric oncology -- Oncological nursing care -- Psychology and psychosocial issues in children with cancer.

[Volume one contents]: -- 1. Development of ocular refraction: lessons from animal experiments -- 2. Preschool vision screening: is it worthwhile? -- 3. Modern treatment of amblyopia -- 4. Retinopathy of prematurity: molecular mechanism of disease -- 5. Screening for retinopathy of prematurity -- 6. Controversies in the management of infantile cataract -- 7. Management of infantile glaucoma -- 8. Pediatric ocular oncology -- 9. Paediatric electrophysiology: a practical approach -- 10. Clinical and molecular genetic aspects of Leber's congenital amaurosis -- 11. Childhood stationary retinal dysfunction syndromes -- 12. Childhood retinal detachment --13. Eye manifestations of intrauterine infections -- 14. Nonaccidental injury. The pediatric ophthalmologist's role.[Volume two contents]: -- pt. 1. Optic nerve -- 1. Optic neuritis and multiple sclerosis -- 2. Ischemic optic neuropathies -- 3. Optic disc drusen -- 4. Inherited optic neuropathies -- ch. 5. Optic nerve tumours -- 6. Traumatic optic neuropathy ... -- pt. 2. Investigations -- 7. Imaging the nerve fiber layer and optic disc -- 8. Functional neuroanatomy of the human visual system ... -- 9. Investigating visual function with multifocal visual evoked potentials -- pt. 3. Retinal disorders -- 10. Autoimmune retinopathies -- 11. Retinal research : application to clinical practice -- pt. 4. Systemic disease -- 12. Chorioretinal lesions in infectious diseases of neuroophthalmic interest -- 13. Giant cell arteritis -- pt. 5. Oculomotility -- 14. Cerebral control of eye movements -- 15. Chronic progressive external ophthalmoplegia ... -- 16. Treatment of specific types of nystagmus -- pt. 6. Rehabilitation -- 17. Rehabilitation in neuroophthamology.[Volume three contents]: -- Epidemiology of Pediatric Strabismus / Amy E. Green-Simms and Brian G. Mohney -- Changes in Strabismus Over Time: The Roles of Vergence Tonus and Muscle Length Adaptation / David L. Guyton -- A Dissociated Pathogenesis for Infantile Esotropia / Michael C. Brodsky -- The Monofixation Syndrome: New Considerations on Pathophysiology / Kyle Arnoldi -- Visual Cortex Mechanisms of Strabismus: Development and Maldevelopment / Lawrence Tychsen -- Neuroanatomical Strabismus / Joseph L. Demer -- Congenital Cranial Dysinnervation Disorders: Facts and Perspectives to Understand Ocular Motility Disorders / Antje Neugebauer and Julia Fricke -- The Value of Screening for Amblyopia Revisited / Jill Carlton and Carolyn Czoski-Murray -- The Brückner Test Revisited / Michael Gräf -- Amblyopia Treatment 2009 / Michael X. Repka -- Best Age for Surgery for Infantile Esotropia: Lessons from the Early vs. Late Infantile Strabismus Surgery Study / H. J. Simonsz, G. H. Kolling and Early vs. Late Infantile Strabismus Surgery Study Group -- Management of Congenital Nystagmus with and without Strabismus / Anil Kumar, Frank A. Proudlock and Irene Gottlob -- Surgical Management of Dissociated Deviations / Susana Gamio -- Surgical Implications of the Superior Oblique Frenulum / Burton J. Kushner and Megumi Iizuka -- Pearls and Pitfalls in Surgical Management of Paralytic Strabismus / Seyhan B. Özkan -- Modern Treatment Concepts in Graves Disease / Anja Eckstein and Joachim Esser.

Developmental bone biology -- Imaging approaches for epiphyseal assessment -- Developmental dysplasia of the hip -- Legg-Calve-Perthes Disease -- Coxa Vara in developmental and acquired abnormalities of the femur -- Developmental disorders of the knee -- Deformities due to disorders primarily affecting the epiphyses and metaphyses -- Lower extremity length discrepancies -- Skeletal dysplasias -- Epiphyseal and metaphyseal involvement with metabolic, inflammatory, neoplastic, infectious, and hematologic disorders.

Part 1.Trauma Overview --Polytrauma in the Pediatric Patient /Joshua M. Abzug and Martin J. Herman --The Mangled Extremity in Children /Sapan D. Gandhi, Joshua M. Abzug and Martin J. Herman --Compartment Syndrome /Baxter Willis --Part 2.Spine --Cervical Spine Injuries in Children /Steven W. Hwang, Per D. Trobisch, Andrew Jea and Amer F. Samdani --Thoracic and Lumbar Spine Injuries /Hitesh Garg, Joshua Pahys and Patrick J. Cahill --Part 3.Upper Extremity --Supracondylar Humerus Fractures /Joshua M. Abzug, Dan A. Zlotolow and Scott H. Kozin --Upper Extremity Replantation in Children /Joshua M. Abzug, Dan A. Zlotolow and Scott H. Kozin --Part 4.Lower Extremity --Pediatric Hip Fractures and Dislocations /James J. McCarthy, Kenneth J. Noonan and Sapan D. Gandhi --Pediatric Proximal Tibial Fractures with Vascular Compromise /William Hennrikus and Tamara Pylawka --Open Tibia Fractures in Children and Adolescents /Joseph Rosenblatt and Shannon D. Safier --Part 5.Infection --Septic Hip /Peter D. Pizzutillo and Megan Gresh --Necrotizing Fasciitis /Kevin J. Little and Joshua M. Abzug --Part 6.Other --Slipped Capital Femoral Epiphysis /Panagiotis Peter Glavas and B. David Horn.

Antibiotic therapy for acute otitis, rhinosinusitis, and pharyngotonsillitis -- Pediatric hearing assessment -- Speech, voice and, swallowing assessment -- Methicillin-resistant staphylococcus aureus (MRSA) infections of the head and neck in children -- Polysomnography in children -- Otology -- External otitis -- Diagnosis and management of otitis media -- Tympanostomy tubes and otorrhea -- Chronic disorders of the middle ear and mastoid (tympanic membrane perforations and cholesteatoma) -- Congenital hearing loss (sensorineural and conductive) -- Implantable hearing devices -- Rhinology -- Pediatric facial fractures -- Pediatric epistaxis -- Nasal obstruction in the neonate -- Pediatric allergic nose -- Acute and chronic rhinosinusitis -- Head and neck -- Congenital head and neck masses -- Pediatric stridor -- Inflammatory disorders of the pediatric airway -- Tracheostomy in children -- Cleft lip and palate -- Cough -- Hoarseness in children -- Adenotonsillar disease -- Sleep-disordered breathing (SDB) in children -- Pediatric vascular tumors -- Emergencies in pediatric otolaryngology -- Foreign body management -- Deep space neck infections in the pediatric population -- Complications of acute otitis media -- Complications of sinusitis.

section I. Concept of normality -- ch. 1. Describing normality -- ch. 2. General aspects of history taking and interviewing -- section II. Specific aspects of history taking -- ch. 3. Three basic steps in diagnosis -- ch. 4. History taking by systems -- section III. Physical examination -- ch. 5. General physical examination -- ch. 6. Head, neck and sensory organs -- ch. 7. Chest (including heart and lungs) -- ch. 8. Abdomen and genitalia -- ch. 9. Skin -- ch. 10. Musculoskeletal system -- ch. 11. Central nervous system -- section IV. Special examinations -- ch. 12 A. Physical diagnosis of the newborn -- B. The Adolescent -- C. Developmental and behavioral assessment -- D. Physical and sexual abuse.

Providing family-centered care in pediatric physical therapy / Elena M. Spearing -- Development -- Motor development in the normal child / Emilie J. Aubert -- Assessment and testing of infant and child development / Susan K. Brenneman and Jan Stephen Tecklin -- Neurological disorders -- The infant at high-risk for developmental delay / Diane Versaw-Barnes and Audrey Wood --The infant and child with cerebral palsy / Jane Styer-Acevedo -- Spina Bifida / Elena Tappit-Emas -- Traumatic injury to the central nervous system: brain injury / Amy Both -- Traumatic and atraumatic spinal cord injury in pediatrics / Heather Atkinson and Elena M. Spearing -- Neuromuscular disorders in childhood: physical therapy intervention / Allan M. Glanzman and Jean M. Flickinger -- Mental retardation: focus on Down Syndrome / Dolores B. Bertoti and Dale E. Smith -- Adaptive equipment and environmental aids for children with disabilities / Emilie J. Aubert -- Musculoskeletal disorders -- Orthopedic management / Meg Stanger -- Traumatic disorders and sports injuries / Joe Molony and Donna Merckel -- Juvenile idiopathic arthritis / Susan E. Klepper -- Other medical/surgical disorders -- Pediatric oncology / Victoria Gocha Marchese -- Rehabilitation of the child with burns / Suzanne F. Migliore -- Cardiac disorders / Heather Brossman -- Pulmonary disorders in infants and children and their physical therapy management / Jan Stephen Tecklin -- Physical therapy in the educational environment / Karen Yundt Lunnen and Rita F. Geddes.

"Pediatric Radiation Oncology is the definitive text and reference on use of radiation therapy for childhood cancer. The fifth edition reviews all significant recent clinical trials--including, for the first time, significant European clinical trials--and provides increased coverage of international and Third World issues. The latest cancer staging guidelines are included. New chapters cover psychosocial aspects of radiotherapy for the child and family and medical management of pain, nausea, nutritional problems, and blood count depression in the child with cancer"--Provided by publisher.

Chest radiographs -- Lateral neck radiographs -- Abdominal radiographs -- Skull radiographs -- Long bone and extremity radiographs -- CT scan review.

Pediatric imaging / Johan G. (Hans) Blickman -- Chest / Johan G. (Hans) Blickman and Lya Van Die -- Heart / Rajesh Krishnamurthy and Johan G. (Hans) Blickman -- Gastrointestinal tract / Bruce R. Parker and Johan G. (Hans) Blickman -- Accessory organs of digestion / Bruce R. Parker and Johan G. (Hans) Blickman -- Genitourinary tract / Johan G. (Hans) Blickman and Carla Boetes -- Skeletal system / Johan G. (Hans) Blickman and Geert Vanderschueren -- Brain imaging / Patrick D. Barnes -- Spine imaging / Patrick D. Barnes -- Head and neck imaging / Patrick D. Barnes.

Adolescent medicine / Mark F. Ditmar -- Behavior and development / Mark F. Ditmar -- Cardiology / Thomas J Starc, Constance J. Hayes, and Allan J. Hordof -- Dermatology / Kimberly D. Morel, Vivian A. Lombillo, and Maria C. Garzon -- Emergency medicine / Joan Bregstien, Cindy Ganis Roskind, and F. Meridith Sonnett -- Endocrinology / Sharon E. Oberfield, Mary Pat Gallagher, and Daniel Esten Hale -- Gastroenterology / Andrew B. Grossman and Chris A. Liacouras -- Genetics / Kwame Anyane-Yeboa -- Hematology / Steven E. McKenzie -- Immunology / Georg A. Hollander and Anders Fasth -- Infectious diseases / Mark F. Ditmar -- Neonatology / Philip Roth -- Nephrology / Robert L. Seigle and Martin A. Nash -- Neurology / Kent R. Kelley -- Oncology / Richard Aplenc, Emily G. Lipsitz, and Peter C. Adamson -- Orthopedics / Benjamin D. Roye -- Pulmonology / Robert W. Wilmott and Bradley A. Becker -- Rheumatology / Carlos D. Rose ... [et al.].

The History of Sedation -- Procedural Sedation: Let's Review the Basics - The Pediatrician's Perspective -- Sedation Policies, Recommendations, and Guidelines Across the Specialties and Continents -- Sedation Scales and Discharge Criteria: How Do They Differ? Which One to Choose? Do They Really Apply to Sedation? -- Physiological Monitoring for Procedural Sedation: The Routine and Beyond -- The Pediatric Airway: Anatomy, Challenges, and Solutions -- Pediatric Physiology: How Does it Differ from Adults? -- Pharmacology and Clinical Application of Sedatives, Analgesics, and Adjuncts -- Pharmacokinetics and Pharmacodynamics in the Pediatric Population -- Billing and Reimbursement for Sedation Services -- The Pediatric Hospital Medicine Sedation Service: Models, Protocols, and Challenges -- The Anesthesia Directed Sedation Service: Models, Protocols, and Challenges -- Sedation in the Intensive Care Unit: Challenges, Outcomes, and Future Strategies -- Sedation for Pediatric Gastrointestinal Procedures -- Sedation in the Emergency Department: A Complex and Multifactorial Challenge -- Sedation of Pediatric Patients for Dental Procedures -- Pediatric Sedation: The European Experience and Approach -- Pediatric Sedation in the Underdeveloped Third World: An African Perspective: Models, Protocols, and Challenges -- Pediatric Sedatives and the Food and Drug Administration: Challenges, Limitations, and Drugs in Development -- Incidence and Stratification of Adverse Events Associated with Sedation: Is There a Benchmark? -- Medicolegal Risks and Outcomes of Sedation -- Designing a Safe and Reliable Sedation Service: Adopting a Safety Culture -- Intravenous Infusions for Sedation: Rationale, State of the Art, and Future Trends -- Use of Complementary and Alternative Medicine in Pediatric Sedation -- The Future of Pediatric Sedation.

V.1. Pages 1-768 -- v.2. pages 769-1738.

Office urology -- Pediatric urology facts and figures -- Radiographic imaging -- Urinary tract infections -- Voiding dysfunction, urinary incontinence, and urodynamics -- Hematuria: gross and microscopic -- Office procedures -- Genetic diseases and associated urologic manifestations -- Genitalia -- Penis and scrotum: congenital and acquired anomalies -- Hypospadias -- Varicoceles, hernias, and hydroceles -- Testicles: undescended, retractile, and ascended -- Acute scrotum -- Urinary tract -- Hydronephrosis: prenatal and postnatal -- Vesicoureteral reflux -- Urinary tract obstruction -- Tissue engineering and regenerative medicine: current concepts -- Miscellaeous topics -- Adolescent urology -- Laparoscopy in the pediatric population -- Genitourinary tumors -- Genitourinary trauma.

pt. 1. Foundations of collaborative care -- pt. 2. Collaboration with pediatricians in specific settings -- pt. 3. Collaboration with pediatricians in treatment of specific disorders -- pt. 4. Future directions in pharmacological collaboration.

General pediatrics -- The newborn infant -- The cardiovascular system -- The respiratory system -- The gastrointestinal tract -- The urinary tract -- The neuromuscular system -- Infectious diseases and immunology -- Hematologic and neoplastic diseases -- Endocrine, metabolic, and genetic disorders -- The adolescent.

Part I. Function and Dysfunction of the Pelvic Floor and Viscera -- Functional Anatomy of the Pelvic Floor and Lower Urinary Tract / Daniele Perucchini and John O. L. DeLancey -- Neural Control of Pelvic Floor Muscles / David B. Vodušek -- The Effects of Pregnancy and Childbirth on the Pelvic Floor / Kaven Baessler and Bernhard Schüssler -- Muscle Function and Ageing / Brenda Russell and Linda Brubaker -- Urinary Incontinence and Voiding Dysfunction / Annette Kuhn and Bernhard Schüssler -- Pelvic Organ Prolapse / Peggy A. Norton -- Anal Incontinence, Constipation, and Obstructed Defecation / Abdul H. Sultan and A. Muti Abulaffi -- Overactive Pelvic Floor Muscles and Related Pain / Wendy F. Bower -- Part II. Evaluation of the Pelvic Floor -- Clinical Evaluation of the Pelvic Floor Muscles / Diane K. Newman and Jo Laycock -- Examination of Patients with Pelvic Organ Prolapse / Ursula M. Peschers Urodynamics / Ursula M. Peschers -- Applying Urodynamic Findings to Clinical Practice / Christopher K. Payne -- Anorectal Physiology / David Z. Lubowski and Michael L. Kennedy -- Ultrasound Imaging / Kaven Baessler and Heinz Kölbl -- Magnetic Resonance Imaging / Thomas Treumann, Ralf Tunn and Bernhard Schüssler -- Electrophysiology / Clare J. Fowler and David B. Vodušek -- Outcome Measures in Pelvic Floor Rehabilitation / Kate H. Moore and Emmanuel Karantanis -- Part III. Techniques of Pelvic Floor Rehabilitation and Muscle Training -- Concepts of Neuromuscular Rehabilitation and Pelvic Floor Muscle Training / Jo Laycock -- Exercise, Feedback, and Biofeedback / Pauline E. Chiarelli and Kate H. Moore -- Electrical Stimulation / Wendy F. Bower -- Extracorporeal Magnetic Stimulation / Alastair R. Morris and Kate H. Moore -- Devices / Ingrid Nygaard and Peggy A. Norton -- Alternative Methods to Pelvic Floor Muscle Awareness and Training / Kaven Baessler and Barbara E. Bell -- Part IV. Treatment: Condition-Specific Assessment and Approaches -- Behavioral Treatment / Kathryn L. Burgio -- Stress Urinary Incontinence / Jo Laycock -- Evidence for the Effectiveness of Pelvic Floor Muscle Training in the Treatment and Antenatal Prevention of Female Urinary Incontinence / E. Jean C. Hay-Smith and Kate H. Moore -- Postpartum Management of the Pelvic Floor / Pauline E. Chiarelli -- Role of a Perineal Clinic / Ranee Thakar -- Overactive Bladder / Kathryn L. Burgio, Dudley Robinson and Linda Cardozo -- Sexual Dysfunction and the Overactive Pelvic Floor / Wendy F. Bower -- Anal Incontinence and Evacuation Difficulties / Christine Norton -- Incontinence During Sports and Fitness Activities / Alain P. Bourcier -- Pelvic Organ Prolapse - Pessary Treatment / Jane A. Schulz and Elena Kwon -- Part V. What to Do if Physiotherapy Fails? -- Stress Urinary Incontinence: Choice of Surgery / Stuart L. Stanton -- Genital Prolapse: Surgery for Failed Conservative Treatment / Stuart L. Stanton -- The Anal Sphincter / Klaus E. Matzel, Manuel Besendörfer and Stefanie Kuschel.

Part 1: Prehospital care, diagnostic tools and resuscitation strategies -- Part 2: Surgical strategies in Penetrating Trauma to Head, Face, and Neck -- Part 3: Surgical Strategies in Penetrating Trauma to the Chest -- Part 4: Surgical Strategies in Penetrating Trauma to the Abdomen and Pelvis -- Part 5: Surgical strategies in Penetrating Trauma and Orthopedic Injuries -- Part 6: Peripheral Arterial Injuries -- Part 7: Other topics.

Clinical and epidemiological foundations / Eric Taylor -- Biological foundations / Sarah Curran -- Diagnosis and assessment / Kapil Sayal -- Psychological assessment / Jody Warner-Rogers -- Medical investigations and tests / Angie Stevens and Gillian Baird -- Making a case formulation : differential diagnosis and recognizing comorbidity / Wai Chen -- Education and advice / Maxine Sinclair -- Pharmacotherapy in ADHD / Paramala J. Santosh -- Behavioural and cognitive approaches / Maxine Sinclair -- ADHD and sleep disorders / Paul Gringras, Adam Jaffe and Stephen Sheldon -- Aspects of medical management / Eric Taylor and Peter Hill -- ADHD in preschool children / Margaret Thompson and Edmund Sonuga-Barke -- Hyperactivity disorders in children with mental retardation / Emily Simonoff -- The clinical assessment and treatment of ADHD in adults / Phillip J. Asherson and J.J. Sandra Kooij.

HPLC analysis and purification of peptides / Colin T. Mant ... [et al.] -- Identification of proteins based on MS/MS spectra and location of posttranslational modifications / Kathryn L. Stone ... [et al.] -- Determination of phosphorylated and O-glycosylated sites by chemical targeting (CTID) at ambient temperature / Gary M. Hathaway -- Synthesis, biosynthesis, and characterization of transmembrane domains of a G protein-coupled receptor / Fred Naider -- Application of topologically constrained mini-proteins as ligands, substrates, and inhibitors / Janelle L. Lauer-Fields ... [et al.] -- Proteolytic profiling of the extracellular matrix degradome / Diane Baronas-Lowell ... [et al.] -- [Beta]-amyloid protein aggregation / Marcus A. Etienne ... [et al.] -- Radiometal-labeled somatostatin analogs for applications in cancer imaging and therapy / Jason S. Lewis and Carolyn J. Anderson -- Cell-penetrating proline-rich peptidomimetics / Josep Farrera-Sinfreu ... [et al.] -- Peptide-mediated targeting of liposomes to tumor cells / Evonne M. Rezler ... [et al.] -- Peptide-mediated delivery of nucleic acids into mammalian cells / Sébastien Deshayes ... [et al.] -- Broth microdilution antibacterial assay of peptides / Laszlo Otvos and Mare Cudic -- Depsipeptide synthesis / Maciej Stawikowski and Predrag Cudic.

PNAs as novel cancer therapeutics / Luca Mologni and Carlo Gambacorti-Passerini -- Medicinal chemistry of plasmid DNA with peptide nucleic acids : a new strategy for gene therapy / Olivier Zelphati ... [et al.] -- Locked nucleic acids (LNA) and medical applications / Henrik Ørum, Andreas Wolter and Lars Kongsbak -- Peptide nucleic acids as agents to modify target gene expression and function / Gan Wang and Peter M. Glazer -- Peptide nucleic acids : cellular delivery and recognition of DNA and RNA targets / David R. Corey --Receptor-specific targeting with complementary peptide nucleic acids conjugated to peptide analogs and radionuclides / Eric Wickstrom, Mathew L. Thakur and Edward R. Sauter -- Morpholinos and PNAs compared / James E. Summerton -- Chemistry of locked nucleic acids (LNA) : design, synthesis and bio-physical properties / Jesper Wengel ... [et al.] -- Recent applications of RNA interference (RNAi) in mammalian systems / Lisa Scherer and John J. Rossi -- Peptide nucleic acids as epigenetic inhibitors of HIV-1 / Shizuko Sei -- Therapeutic uses of peptide nucleic acids (PNA) in oncology / Nadia Zaffaroni, Raffaella Villa and Marco Folini --The many faces of PNA / Peter E. Nielsen -- Modulation of nucleic acid information processing by PNAs : potential use in anti-viral therapeutics / Lionel Bastide, Bernard Lebleu and Ian Robbins -- Targeted gene delivery : the role of peptide nucleic acid / Kenneth W. Liang, Feng Liu and Leaf Huang -- Imaging gene expression in the brain with peptide nucleic acid (PNA) antisense radiopharmaceuticals and drug targeting technology / Ruben J. Boado and William M. Pardridge --The use of PNAs and their derivatives in mitochondrial gene therapy / Paul M. Smith ... [et al.] -- Gene silencing through RNA interference: potential for therapeutics and functional genomics / David O. Azorsa, Spyro Mousses and Natasha J. Caplen -- Transcriptional activation of human CREB gene promoter using bis-PNA (peptide nucleic acid) / Christopher G. Janson ... [et al.].

Peptide-based drug design : here and now / Laszlo Otvos, Jr. -- Strategies for the discovery, isolation, and characterization of natural bioactive peptides from the immune system of invertebrates / Philippe Bulet -- Sequence analysis of antimicrobial peptides by tandem mass spectrometry / Christin Stegemann and Ralf Hoffmann -- The spot technique : synthesis and screening of peptide macroarrays on cellulose membranes / Dirk F.H. Winkler and William D. Campbell -- Analysis of A[beta] interactions using ProteinChip technology / Eleni Giannakis ... [et al.] -- NMR in peptide drug development / Jan-Christoph Westermann and David J. Craik -- Molecular dynamics simulations of peptides / Jeffrey Copps, Richard F. Murphy and Sandor Lovas -- Short linear cationic antimicrobial peptides : screening, optimizing, and prediction / Kai Hilpert, Christopher D. Fjell and Artem Cherkasov -- Investigating the mode of action of proline-rich antimicrobial peptides using a genetic approach : a tool to identify new bacterial targets amenable to the design of novel antibiotics / Marco Scocchi ... [et al.] -- Serum stability of peptides / Håvard Jenssen and Stein Ivar Aspmo -- Preparation of glycosylated amino acids suitable for Fmoc solid-phase assembly / Mare Cudic and Gayle D. Burstein -- Synthesis of O-phosphopeptides on solid phase / David Singer and Ralf Hoffmann -- Peptidomimetics : Fmoc solid-phase pseudopeptide synthesis / Predrag Cudic and Maciej Stawikowski -- Synthesis of toll-like receptor-2 targeting lipopeptides as self-adjuvanting vaccines / Brandon Y. Chua, Weiguang Zeng and David C. Jackson -- Synthesis of a multivalent, multiepitope vaccine construct / Laszlo Otvos, Jr. -- Cysteine-containing fusion tag for site-specific conjugation of therapeutic and imaging agents to targeting proteins / Marina V. Backer ... [et al.].

The discipline of radiation oncology -- Biologic basis of radiation therapy -- Molecular cancer and radiation biology -- Molecular pathophysiology of tumors -- Principles of radiologic physics, dosimetry, and treatment planning -- Photon external-beam dosimetry and treatment planning -- Electron-beam therapy: dosimetry, planning, and techniques -- Three-dimensional conformal radiation therapy: physics, treatment planning, and clinical aspects -- Intensity-modulated radiation treatment techniques and clinical applications -- Image-guided radiation therapy -- Altered fractionation schedules -- Late effects of cancer treatment on normal tissues -- Methodology of clinical trials -- Total-body and hemibody irradiation -- Stereotactic radiosurgery and radiotherapy -- Sterotatic irradiation of tumors outside the central nervous system -- Intraoperative radiotherapy -- Particle beam radiotherapy -- Physics and biology of brachytherapy -- Clinical applications of brachytherapy: low-dose-rate and pulse-dose-rate -- The physics and dosimetry of high-dose-rate brachytherapy -- Clinical aspects and applications of high-dose-rate brachytherapy -- Radioimmunoglobulins and nonsealed radionuclide therapy -- Photodynamic therapy -- Radiation oncology in the developing world -- Chemical modifiers of radiation response -- Oncologic imaging/oncologic anatomy -- Hyperthermia -- Basic concepts of chemotherapy and irradiation interaction -- Skin -- Malignant neoplasms associated with the acquired immunodeficiency syndrome -- Primary intracranial neoplasms -- Pituitary -- Spinal canal -- Eye and orbit -- Ear -- The role of combined radiotherapy and chemotherapy in the management of locally advanced squamous carcinoma of the head and neck -- Nasopharynx -- Nasal cavity and paranasal sinuses -- Salivary glands -- Oral cavity cancer -- Oropharynx -- Hypopharynx cancer -- Larynx -- Unusual nonepithelial tumors of the head and neck -- Management of the neck including unknwon primary tumor -- Thyroid -- Lung -- Mediastinum and trachea --Esophageal cancer -- Tumors of the heart and great vessels -- Breast: stage tis -- Early stage breast cancer -- Breast cancer: locally advanced and recurrent disease, postmastectomy radiation, and systemic therapies -- Stomach -- Cancer of the pancreas -- Liver and hepatobiliary tract -- Colon and rectum -- Anal cancer -- Kidney, renal pelvis, and ureter -- Bladder -- Low-risk prostate cancer -- Intermediate- and high-risk prostate cancer -- Testis -- Penis and male urethra -- Uterine cervix -- Endometrium -- Ovary -- Fallopian tube -- Vagina -- Female urethra -- Carcinoma of the vulva -- Retroperitoneum -- Adrenal gland -- Hodgkin lymphoma -- Non-Hodgkin's lymphoma -- Cutaneous T-cell lymphoma -- Leukemia -- Plasma cell myeloma and plasmacytoma -- Osteosarcoma -- Soft tissue sarcomas (excluding retroperitoneum) -- Central nervous system tumors in children -- Wilms' tumor -- Neuroblastoma -- Rhabdomyosarcoma -- Ewing tumor -- Lymphomas in children -- Unusual tumors in childhood -- Radiotherapy of non-malignant diseases -- Endovascular brachytherapy -- Palliation of brain and spinal cord metastases -- Palliation of bone metastases -- Palliation of visceral recurrences and metastases -- Pain management -- Supportive care and quality of life -- Technology assessment, cost benefit, outcome analysis research and evidence-based radiation oncology -- Ethics, professional values, and legal considerations in radiation oncology -- The economics of radiation oncology.

1. Introduction / D. Watson -- 2. Interactions between stress, food and mood / C.R. Markus -- 3. Mood, cognitive function and nutritional and other supplements / P. Clayton -- 4. The Range of medicinal plants influencing mental and physical performance / T.S.C. Li -- 5. Phyto-oestrogens and cognitive function / S. Kreijkamp-Kaspers and Y.T. van der Schouw -- 6. Ginseng / D.D. Kitts and D.G. Popovich -- 7. Ginkgo biloba and Alzheimer's disease / B.D. Oomah -- 8. Functional ingredients in sports drinks / R.J. Maughan -- 9. Pharmacological functions of green tea polyphenols / T.P. Rao, T. Okubo, D-C. Chu and L.R. Juneja -- 10. Caffeine, mental performance and mood / J.E. James --

We provide a broad overview of human brain development with associated malformations and injuries that occur in the period between early embryogenesis and delivery. The aim of this review is to summarize current understanding of the molecular and environmental cues that shape the developing brain. For each developmental stage, we give examples of disorders that arise from genetic and/or environmental insults to illustrate critical points of neurological susceptibility.

Introduction / Melisa M. Adams -- Reproductive Health Issues / Melisa M. Adams -- Maternal Morbidity / Melisa M. Adams -- Maternal Mortality / Melisa M. Adams -- Infant Morbidity / Melisa M. Adams -- The Continuum of Reproductive Loss from Pregnancy Through Infancy / Melisa M. Adams -- Birth Weight, Gestational Duration, and Fetal Growth / Melisa M. Adams -- Conclusion / Melisa M. Adams.

Perinatal patient safety and professional liability issues /Kathleen Rice Simpson --Integrating cultural beliefs and practices when caring for childbearing women and families /Lynn Clark Callister --Physiologic changes of pregnancy /Susan Tucker Blackburn --Psychosocial adaptation to pregnancy and postpartum /Jeanne Watson Driscoll --Antenatal care /Mary Lee Barron --High-risk pregnancy --Labor and birth /Kathleen Rice Simpson --Fetal assessment during labor /Kathleen Rice Simpson --Pain relief and comfort measures in labor /Patricia A. Creehan --Postpartum care /Dotti C. James --Newborn adaptation to extrauterine life /Debbie Askin --Newborn physical assessment --Newborn nutrition /Jill Janke --Common neonatal complications /Patricia Nash and Joan Renaud Smith.

The site includes data and information for each state, the District of Columbia, Puerto Rico and the United States on prenatal care, low birthweight, infant mortality, poverty, health insurance coverage, and other topics related to maternal and child health.

A historical perspective on the psychiatry of motherhood / I. Brockington -- Diagnostic classification of perinatal mood disorders / A. Riecher-Rössler, A. Rohde -- Maternal adversity, vulnerability, and disease / S.G. Matthews, M.J. Meaney -- Behavioral perinatology / P.D. Wadhwa -- Maternal depression: an adverse early environment / A.J. Beach ... [et al.] -- Perinatal infanticide and suicide / M.G. Spinelli -- Relevance of gonadal hormones to perinatal mood and anxiety disorders / A. Ahokas ... [et al.] --Pharmacotherapy for psychiatric disorders in pregnancy / L.E. Ross ... [et al.] -- Maternal depression in the postpartum period: impact of breast-feeding on treatment planning / Z.N. Stowe, K. Ragan, D.J. Newport -- The use of interpersonal psychotherapy for perinatal mood and anxiety disorders / S. Stuart, M.W. O'Hara -- Group psychotherapy for depression in early stages of motherhood / M. Hofecker-Fallahpour, A. Riecher-Rössler -- Alternative treatment strategies for perinatal depression and anxiety / M. O'Higgins, V. Glover, M. Corral.

Role of the Medical Consultant -- Preoperative Testing -- Perioperative Medication Management -- Perioperative Management of Anticoagulation -- Venous Thromboembolism Prophylaxis -- Prevention of Infective Endocarditis (Bacterial Endocarditis Prophylaxis) -- Surgical Site Infection Prophylaxis -- Anesthesiology for the Nonanesthesiologist -- Abdominal Surgery -- Thoracic Surgery -- Vascular Surgery -- Orthopedic Surgery -- Neurosurgery -- Gynecologic Surgery -- Urologic Surgery -- Bariatric Surgery -- Ophthalmic Surgery -- Otolaryngologic Procedures -- Electroconvulsive Therapy -- Cardiac Disease -- Pulmonary Disease -- Endocrine Disease -- Hematologic Disease -- Cancer -- HIV -- Chronic Kidney Disease -- GI Disease -- Rheumatic Disease -- Neurological Disease -- Psychiatric Conditions -- Substance Abuse -- The Pregnant Surgical Patient -- Postoperative Fever -- Postoperative Hypertension/Hypotension -- Postoperative Arrhythmias -- Perioperative Chest Pain/Dyspnea -- Postoperative Pulmonary Complications -- Postoperative Venous Thromboembolism (DVT and PE) -- Postoperative Fluid, Electrolyte, and Acid/Base Disorders -- Postoperative Renal Failure -- Anemia and Bleeding -- Postoperative Jaundice -- Postoperative Stroke and Seizures -- Postoperative Delirium -- Pain Management.

A history of transfusion / Bruce Spiess and Richard K. Spence -- The contemporary economics of transfusion / Timothy J. Hannon and Kathy Paulson Gjerde -- Blood supplies now and in the future / Mike Fitzpatrick -- Medical ethics, transfusion and the standard of practice / Kenneth Kipnis -- Oxygen transport monitoring: the basis for developing transfusion triggers / Kevin Ward and Ivo Torres Filho -- Physiology of anemia and red blood cell transfusion / Howard Corwin and Paul C. Høbert -- Physiology of hemostasis / Wayne L. Chandler -- Platelet physiology: cellular and protein interactions / Christine S. Rinder -- Iron metabolism and erythopoiesis / Kenneth R. Bridges -- New concepts in oxygen transport / Aryeh Shander, Tanuja S. Rijhwani, and Carmine Gianatiempo -- Infectious risks of transfusion / Eberhard W. Fiebig and Michael P. Busch --Immunomodulation by transfusion / Neil Blumberg and Joanna M. Heal -- Serious acute transfusion reactions / Ira A. Shulman and Aryeh Shander -- A surgeon's guide to blood banking and transfusion medicine / Kimberly W. Sanford and Susan D. Roseff -- Blood storage / Ian Chin-Yee and Richard K. Spence -- Quality control and hospital blood utilization / Kathy Walsh-Kaminsky -- Preoperative autologous donation / F. Mercuriali, G. Inghilleri, and Richard K. Spence -- Erythropoetin therapy / Lawrence T. Goodnough -- Hemoglobin based oxygen carriers / Gregory M.T. Hare and C. David Mazer -- Perfluorocarbon emulsions: artificial gas transport media / Bruce D. Spiess -- Initial resuscitation of the hemorrhaging patient / Richard P. Dutton -- Transfusion and coagulation therapy in trauma and burns / James K. Wright, Harriet W. Hopf, and Lewis J. Kaplan --Acute gastrointestinal bleeding and transfusion management / Richard Peterson, Patricia Parce, and Richard K. Spence -- Coagulation in trauma: dilution and massive transfusion / Richard K. Spence and Anthony Martinez -- Coagulation product use in the perioperative period / Richard K. Spence and Aryeh Shander -- Coagulation monitoring in the perioperative period / Linda Shore-Lesserson and Bruce D. Spiess -- Surgery in patients with acquired platelet and clotting deficiencies / Richard K. Spence and Andrew Green -- Surgery in patients with congenital clotting deficiencies / Richard K. Spence and Andrew Green -- Perioperative implications of anticoagulant and antiplatelet therapy / Jeffrey A. Green -- Pharmacological approaches to prevent or decrease bleeding in surgical patients / Jerrold H. Levy -- Fibrin glue and platelet gel / Bruce Searles and Cody Trowbridge --Anesthesia techniques in blood conservation / Aryeh Shander and Tanuja Rijhwani -- Perioperative red cell salvage and autotransfusion / Jonathan H. Waters -- Intraoperative acute nomovolemic hemodilution / Aryeh Shander and Tanuja S. Rijhwani -- Hypothermia and hemorrhage / Richard P. Dutton -- Surgery in patients with red cell disorders: sickle hemoglobinopathies, polycythemia, and autoimmune hemolytic anemia / Imoigele P. Aisiku -- Surgery in the Jehovah's Witness / Richard K. Spence ... [et al.] -- Coagulation, transfusion, and cardiac surgery / Simon S. Body and David S. Morse -- Blood loss and transfusion alternatives in vascular surgery / Richard K. Spence -- Solid organ transplantation / Nicolas Jabbour, S. Ram Kumar, and Singh Gagandeep -- Blood use in orthopedic surgery / E. Michael Keating and John B. Meding --Blood management in obstetrics and gynecology / Arnold J. Friedman -- Hemorrhage in pediatric patients / Thomas V. Whalen -- Transfusion in oncologic surgery / Patricia A. Ford and Jason Mastoris -- Transfusion and coagulation dysfunction in neurosurgery / Robert S. Graham and J. Chris Zacko -- Transfusion and outcome / Bruce D. Spiess, Richard K. Spence, and Aryeh Shander -- The transfusion decision / Bruce D. Spiess, Richard B. Counts, and Steven A. Gould -- Undertransfusion / Richard K. Spence and Aryeh Shander -- A philosophy of blood management / Aryeh Shander, Richard K. Spence, and Bruce D. Spiess.

Normal TEE Views -- Doppler and Hemodynamics -- Ventricles -- Native Valves -- Prosthetic Valves Transcatheter Valves and Valve Repairs -- Aorta -- Congenital Heart Disease -- Variants, Foreign Material, Masses and Endocarditis -- Ventricular Assist Devices and Heart Transplant -- Hypertrophic Obstructive Cardiomyopathy and Diastolic Dysfunction -- Pericardium.

Evolution of endovascular therapy: diagnostics and therapeutics -- Pathophysiology of vascular disease -- Training and credentialing in vascular and endovascular surgery -- Assessment of vascular patients and indications for therapy -- Anesthesia techniques for endovascular surgery -- Intraprocedural monitoring for endovascular procedures -- Safety considerations for endovascular surgery -- Endovascular intervention suite design -- Angioscopy: instrumentation, techniques, and applications -- Duplex-guided balloon angioplasty from the carotid to the plantar arteries -- Intravascular ultrasound imaging -- Biomaterials: considerations for endovascular devices -- Ancillary endovascular equipment: catheters, guidewires, and procedural considerations -- Balloon angioplasty -- Endovascular intervention for lower extremity deep venous thrombosis -- Remote femoral and iliac artery endarterectomy --Intravascular stents -- Intravascular laser technologies -- Endovascular devices for abdominal aortic aneurysms -- Endovascular devices for thoracic aortic aneurysms -- Critical limb ischemia -- Renal stents -- Inferior vena cava filters: the impact of endovascular technology -- Carotid stenting -- Neuroendovascular interventions -- The current status of hybrid repair of thoracoabdominal aortic aneurysms -- Laparoscopic aortic surgery -- Endovenous surgery -- Thoracic outlet syndrome: endoscopic transaxillary first rib approach: 23 years experience (1985-2008) -- Prevention of lesion recurrence in endovascular devices -- Management of the percutaneous puncture site -- Endovascular practice in Asia-Pacific -- Future imaging and guidance for endovascular procedures.