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  • The Aortic Valve -- Aortic Stenosis -- Aortic Insufficiency -- The Mitral Valve -- Mitral Stenosis -- Mitral Insufficiency -- Tricuspid and Pulmonic Valve Disease -- Prosthetic Valves -- Infective Endocarditis -- Echocardiographic Assessment of the Left Ventricle -- Coronary Artery Disease : Ischemia, Infarction, and Complications -- Coronary Artery Disease : Stress Echocardiography -- Cardiomyopathies -- Diastolic Dysfunction and Echocardiographic Hemodynamics -- Contrast Echocardiography -- Proximal Isovelocity Surface Area and Flow Convergence Methods -- Echocardiography and Its Role in Cardiac Resynchronization Therapy -- Stress, Strain, Speckle, and Tissue Doppler Imaging : Practical Applications -- Stress, Strain, Speckle, and Tissue Doppler Imaging : Practical Applications -- Role of Transesophageal Echocardiography in Mitral Valve Repair -- Intracardiac Echocardiography -- Pericardial Diseases -- Right Heart Diseases -- Cardiac Masses -- Cardiac Trauma -- Echocardiographic Guidance of Procedures.
  • Philosophical and Social Framework of Electronic Medicines Management -- History and Context of Electronic Prescribing in the US and UK -- Organization Benefits of Electronic Prescribing -- EP Systems as a Risk Management Tool -- Data Support for Electronic Medicines Management -- Electronic Medicines Management: Support for Professional Practice -- Electronic Medicines Management and Non-medical Prescribing -- Electronic Prescribing and Future Priorities.
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  • Written entirely by surgical endoscopists, Principles of Flexible Endoscopy for Surgeons presents a comprehensive overview of past, present, and future flexible gastrointestinal endoscopic techniques, with a focus on educating surgeons who may or may not already have the skills to perform flexible endoscopy. In addition to the endoscopic management of surgical issues, the volume describes the role of surgery in the management of endoscopic complications. Basic as well as advanced flexible endoscopic techniques are presented in both a didactic and visual mode, with representative endoscopic images and video clips. Recent endoscopic advancements which are not routinely a core component of surgical training programs are also covered in detail. Extensively illustrated with endoscopic images and accompanied by a DVD, Principles of Flexible Endoscopy for Surgeons is a valuable resource for surgeons on all facets of flexible endoscopy.
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    Introduction to fluorescence -- Instrumentation for fluorescence spectroscopy -- Fluorophores -- Time-domain lifetime measurements -- Frequency-domain lifetime measurements -- Solvent and environmental effects -- Dynamics of solvent and spectral relaxation -- Quenching of fluorescence -- Mechanisms and dynamics of fluorescence quenching -- Fluorescence anisotropy -- Time-dependent anisotropy decays -- Advanced anisotropy concepts -- Energy transfer -- Time-resolved energy transfer and conformational distributions of biopolymers -- Energy transfer to multiple acceptors in one, two, or three dimensions -- Protein fluorescence -- Time-resolved protein fluorescence -- Multiphoton excitation and microscopy -- Fluorescence sensing -- Novel fluorophores -- DNA technology -- Fluorescence-lifetime imaging microscopy -- Single-molecule detection -- Fluorescence correlation spectroscopy -- Radiative decay engineering : metal-enhanced fluorescence -- Radiative decay engineering : surface plasmon-coupled emission -- Appendix I. Corrected emission spectra -- Appendix II. Fluorescent lifetime standards -- Appendix III. Additional reading -- Answers to problems.
  • Fulltext ClinicalKey
    Chapter 1. The Effects of Gender in Neonatal Medicine / Tove S. Rosen, David Bateman -- Chapter 2. Sexual Development, Growth, and Puberty in Children / Gaya S. Aranoff, Jennifer J. Bell -- Chapter 3. Gender Differences in Pediatric Pulmonary Disease / Beverley J. Sheares -- Chapter 4. Gender-Specific Aspects of Pediatric Hematology and Oncology / James H. Garvin Jr. -- Chapter 5. Gender Differences in Neurological Conditions of Children / David M. Kaufman -- Chapter 6. Gender and Sports: Past, Present, and Future / Jordan D. Metzl -- Chapter 7. Gender Differences in the Functional Organization of the Brain / Ruben C. Gur, Tamara Bockow, Raquel E. Gur -- Chapter 8. Sexual Differentiation of Brain Structure and Function / Margaret M. McCarthy -- Chapter 9. The Sexed and Gendered Brain / William Byne -- Chapter 10. Age and Gender-Specific Patterns of Neurologic Illness / Joan Amatniek, Karin Sorra, Lauren Frey, W. Allen Hauser -- Chapter 11. Gender Differences in Stroke / Rebecca F. Gottesman, Argye E. Hillis -- Chapter 12. Gender Differences in Disorders that Present to Psychiatry / Mary V. Seeman -- Chapter 13. Hormone Replacement Therapy and Cognitive Function / Mary Sano, Diane Jacobs, Katya Gaynor -- Chapter 14. Gender and the Heart: Sex-Specific Differences in the Normal Myocardial Anatomy and Physiology / Marianne J. Legato, Jaswinder K. Leghe -- Chapter 15. Gender-Specific Aspects of Selected Coronary Heart Disease Risk Factors: A Summary of the Epidemiologic Evidence / Shari S. Bassuk, JoAnn E. Manson -- Chapter 16. Dyslipidemia Management in Women and Men: Exploring Potential Gender Differences / Kavita Sharma, Christian D. Nagy, Roger S. Blumenthal -- Chapter 17. Gender Differences in the Role of Stress and Emotion in Cardiovascular Function and Disease / David E. Anderson, Margaret A. Chesney -- Chapter 18. The Role of Sex and Gender in Cardiothoracic Surgery / Sandhya K. Balaram, Justin D. Blasberg -- Chapter 19. Gender Differences in Asthma / Robert H. Lim, Lester Kobzik -- Chapter 20. Gender Issues in Venous Thromboembolism / Susan Murin, Kathryn Bilello, Lisa Moores, Aaron Holley -- Chapter 21. Sleep in Women: Gender Differences in Health and Disease / Shirin Shafazand -- Chapter 22. Are Women More Susceptible to Chronic Obstructive Pulmonary Disease? / Kenneth R. Chapman -- Chapter 23. The Gender-Specific Aspects of Lung Cancer / Rebecca L. Toonkel, Charles A. Powell -- Chapter 24. Gender-Specific Considerations in Pulmonary Hypertension / Deborah Shure -- Chapter 25. Sex and Gender Differences in Pulmonary Manifestations of Autoimmune Disease / Muddassir Aliniazee, Marilyn K. Glassberg -- Chapter 26. Benign Metastasizing Leiomyoma and Lymphangioleiomyomatosis: Lung Diseases of Women / Muddassir Aliniazee, Marilyn K. Glassberg -- Chapter 27. Gender Differences in Susceptibility, Outcomes, and Pathophysiology of Sepsis / Kristy A. Bauman, MeiLan K. Han -- Chapter 28. Inflammatory Bowel Disease in Women / Melissa Munsell, Marc Sonenshine, Mary L. Harris -- Chapter 29. Disorders of Defecation in Women / Susan L. Gearhart -- Chapter 30. Idiopathic Gastroparesis: Gender Aspects / Henry P. Parkman -- Chapter 31. Liver Disease in Women / Karen Krok, Ayman Koteish -- Chapter 32. Gender Differences in Irritable Bowel Syndrome / Octavia Pickett-Blakely, Linda A. Lee, Gerald Mullin -- Chapter 33. Contraception / Karen Feisullin, Carolyn Westhoff -- Chapter 34. Infertility: The Male / Howard H. Kim, Peter N. Schlegel, Marc Goldstein -- Chapter 35. Infertility and In Vitro Fertilization / Elizabeth Barbieri, Sonya Kashyap, Pak H. Chung -- Chapter 36. Female Sexual Health / Barbara D. Bartlik, Julie A. Kolzet, Nazia Ahmad, Tahmina Parveen, Sarah Alvi -- Chapter 37. Male Sexual Dysfunction / Serkan Deveci, John P. Mulhall -- Chapter 38. Pelvic Pain: Urogenital Female Disorders / Andrew T. Goldstein, Lara J. Burrows -- Chapter 39. Lower Urogenital Tract Dysfunction in Men and Women / Doreen E. Chung, Alexis E. Te, Renuka Tyagi -- Chapter 40. Aging and the Lower Urogenital System / Catherine E. DuBeau -- Chapter 41. Menopause / Gloria Bachmann, Nora J. Doty -- Chapter 42. The Differences between Male and Female Breast Cancer / Coral Omene, Amy Tiersten -- Chapter 43. Difference in Germ Cell Tumors of the Reproductive Tract in Men and Women / Nicole LaNatra, Amy Tiersten -- Chapter 44. Gender Differences in Hereditary Cancer Syndromes: Risks, Management, and Testing for Inherited Predisposition to Cancer / Wendy K. Chung -- Chapter 45. Gender Differences in Emerging Infectious Diseases / Sharon Lewin -- Chapter 46. Sexually Transmitted Infections in Men and Women / Anne M. Rompalo, Khalil G. Ghanem -- Chapter 47. Infections in Pregnancy / Emilia Mia Sordillo, Bruce Polsky -- Chapter 48. Adult Immunization in Women and Men / Sally L. Hodder, Debra Chew, Shobha Swaminathan -- Chapter 49. Gender Differences in Autoimmune Diseases: Immune Mechanisms and Clinical Applications / Nabih I. Abdou, Virginia Rider -- Chapter 50. Hormones and Cytokines: Gender-Specific Effects / Maurizio Cutolo -- Chapter 51. Prolactin and Autoimmunity / Sara E. Walker -- Chapter 52. Sex Hormones and Immune Function / Robert G. Lahita -- Chapter 53. Pregnancy and Autoimmune Rheumatic Disease / Carl A. Laskin, Christine A. Clark, Karen A. Spitzer -- Chapter 54. Oral Contraceptives and Autoimmune Diseases / Taraneh Mehrani, Michelle Petri -- Chapter 55. Gender-Specific Issues in Organ Transplantation / Hilary Sanfey Chapter 56. Endogenous Sex Hormones and Risk of Type 2 Diabetes Mellitus in Men and Women / Sherita Hill Golden -- Chapter 57. Thyroid Disorders and Pregnancy / Matthew Kim -- Chapter 58. Sexual Function and Dysfunction in Men and Women / Karen Elizabeth Boyle, Arthur L. Burnett -- Chapter 59. Osteoporosis in Men and Women / Kendall F. Moseley, Suzanne M. Jan de Beur -- Chapter 60. Testosterone Replacement Therapy in Men and Women / Diala El-Maouche, Adrian Dobs.
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  • Part 1. Principles of Health Interoperability -- The Health Information Revolution -- Why Interoperability is Hard -- Models -- UML and XML -- Privacy -- Standards Development Organizations -- Part 2. HL7 and Interchange Formats -- HL7 Version 2 -- The HL7 V3 RIM -- Constrained Information Models -- Clinical Document Architecture -- HL7 Dynamic Model -- IHE XDS -- Part 3. SNOMED and Terminology -- Clinical Terminology -- Coding and Classification Schemes -- SNOMED CT -- SNOMED CT Concept Model -- Using SNOMED and HL7 Together.
  • Drs. Gerhard Meisenberg and William H. Simmons covers the latest developments in the field, including genome research, the molecular basis of genetic diseases, techniques of DNA sequencing and molecular diagnosis, and more. An updated and expanded collection of figures and access to the fully searchable text, USMLE test questions, clinical case studies and more makes this the resource for understanding all aspects of biochemistry needed in medicine. Tap into the most up-to-date coverage of new developments in genome research, the molecular basis of genetic diseases, techniques of DNA sequencing and molecular diagnosis, RNA interference as a mechanism both for regulation of gene expression and for anti-viral defense, and more. Gain a clear visual understanding through new and updated figures that provide current and relevant guidance. Make the link between basic science and clinical medicine with new Clinical Example boxes in nearly every chapter. Focus on the most essential biochemistry principles and how they apply to clinical medicine.
  • Principles of medical biology v. 2-15, 1995-2004., ScienceDirect
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  • "Principles of Medicine in Africa combines classical clinical medicine with a rich understanding of the major environmental and cultural influences on health and disease, providing comprehensive guidance for anyone intending to practise medicine in Africa. Disease is presented in the context of family and culture, and the effects of inequality and problems of limited resources are addressed."--Excerpt from publisher notes.
  • For physicians and surgeons entrusted with the care of patients with morbid obesity and related diseases; also for nurses and other professionals on the team. âPrinciples of Metabolic Surgeryâ delivers a succinct account of current knowledge and an excellent overview of modern treatment strategies for morbid obesity. Attractively designed, this user-friendly textbook provides the latest on therapy, monitoring, and management, including: -Completely up-to-date coverage of modern metabolic surgery -Current understanding of the pathophysiology of morbid obesity -Current clinical therapy strategies for conservative and surgical approaches -Recent references In concise, readable chapters, this well-illustrated textbook outlines major concerns and considerations surrounding metabolic surgery. With respect to new insights from basic and clinical research, clear guidelines and practical clinical advice are given to improve the outcome of treatment for morbid obesity.
  • Minimal extracorporeal circulation (MECC) systems have been designed in order to reduce dramatically the side-effects of conventional extracorporeal circulation while serving as a safe perfusion technique for open heart surgery with cardiopulmonary bypass. However, the low penetration of this technology in contemporary practice means that few surgical centres have accumulated sufficient experience to share it with the scientific community. Furthermore, much of the knowledge on the use of MECC systems in cardiac surgery is widely dispersed in the literature. This book aims to provide an up-to-date and comprehensive overview of MECC, offering practical advice on how to use MECC systems for those new to the field as well as tips, pitfalls, results, and latest developments. It also offers a systematic review of all published studies on a variety of MECC systems. The book will enable physicians to gain a better understanding of these new systems as well as to understand the rationale for their use in cardiac surgery. MECC requires a multidisciplinary approach, and this book will serve as an essential reference for all health care professionals working in the cardiac surgical operating room, in particular cardiothoracic surgeons, anaesthesiologists, and perfusionists.
  • Cardiovascular genetics / Christopher Semsarian and Christine Seidman -- Molecular biology applications in cardiovascular medicine / Eugene Yang ... [et al.] -- Genomics and its application to cardiovascular disease / Robert Roberts -- Gene therapy and cardiovascular diseases / Yi Chu, Neal L. Weintraub, and Donald D. Heistad -- Stem cells and progenitor cells in cardiovascular disease / Jalees Rehman and Keith L. March -- Development of the vertebrate heart / Mabelle Ashe and David Bader -- Inherited myocardial diseases / Elizabeth M. McNally -- Receptor-signaling pathways in heart failure / Shayela Suvarna ... [et al.] -- Recent insights into the molecular pathophysiology of viral myocarditis / Tony Tran, Roger D. Rossen, and Douglas L. Mann -- Genetic underpinnings of cardiogenesis and congenital heart disease / Vidu Garg and Deepak Srivastava -- Coronary artery development / Mark W. Majesky -- Atherosclerosis / George A. Stouffer -- Antiplatelet drugs / Karlheinz Peter -- Myocardial infarction / D. Douglas Miller and Steven C. Herrmann -- Transplant arteriopathy: pathology, pathogenesis, and prospects for treatment / Joannis Vamvakopoulos ... [et al.] -- Thrombolysis: scientific basis for current theory / Guy L. Reed III -- Coronary restenosis / Julius Aitsebaomo ... [et al.] -- Induction and patterning of purkinje fiber network / Takashi Mikawa ... [et al.] -- Mechanisms of sudden cardiac death / Wayne E. Cascio -- Gene therapy for cardiac arrhythmias / J. Kevin Donahue and Eduardo Marbçn -- Genetics and arrhythmias / Kui Hong and Ramon Brugada -- Therapeutic angiogenesis for ischemic vascular disease / Jai Pal Singh and J. Anthony Ware -- Nitric oxide in cardiovascular biology and pathophysiology / Marshall A. Corson -- Vasculitis / Ronald J. Falk and J. Charles Jennette -- Primary pulmonary hypertension / Evangelos D. Michelakis and Stephen L. Archer -- The molecular basis of cerebrovascular malformations / Douglas A. Marchuk -- Thrombotic vascular disease / Stephan Moll and Gilbert C. White II -- Risk factors / Ngoc-Anh Le and W. Virgil Brown -- Vascular aging: from molecular to clinical cardiology / Samer S. Najjar and Edward G. Lakatta -- Oxidative stress / Nageswara R. Madamanchi and Marschall S. Runge -- Diabetes mellitus: an important cardiovascular risk factor / David R. Clemmons -- Vascular inflammation as a cardiovascular risk factor / Allan R. Brasier and Adrian Recinos III, and Mohsen S. Eledrisi.
  • Section I. Introduction of cancer biology and cancer genetics -- Section II. Molecular techniques -- Section III. Molecular tests and cancer management -- Section IV. Molecular diagnostics of common malignancies -- Section V. Molecular basis of cancer therapeutics -- Section VI. Personalized medicine and targeted therapy of cancer -- Section VII. Future of molecular diagnostics and personalized cancer medicine.
  • The molecular basis of intervertebral disc degeneration / Leo, B.M.; Walker, M.H.; Anderson, D.G. -- Genetics of degenerative disc disease / Kurpad, S.N.; Lifshutz, J. -- Gene therapy for degenerative disc disease / Kim, J.; Gilbertson, L.G.; Kang, J.D. -- Bone morphogenetic proteins: spinal fusion applications / Bomback, D.A.; Grauer, J.N. -- Cellular and gene therapy approaches to spinal cord injury / Steinmetz, M.P.; Liu, J.K.; Boulis, N.M. -- Neural stem cell transplantation for spinal cord repair / Iwanami, A. ... [et al.] -- Contemporary applications of functional and stereotactic techniques for molecular neurosurgery / Couldwell, W. -- Xeno-neurotransplantation / Schumacher, J.M. -- Molecular mechanisms of epilepsy and gene therapy / Telfeian, A.; Celix, J.; Dichter, M. -- Adeno-associated viral (AAV) vectors for clinical gene therapy in the brain / Samulski, R.J. -- Molecular mechanisms of epilepsy and gene therapy / Telfeian, A.; Celix, J.; Dichter, M. -- Emerging treatment of neurometabolic disorders / Brady, R.O.; Brady, R.O. Jr. -- Gene therapy for Parkinson's disease / Hadaczek, P.; Daadi, M.; Bankiewicz, K. -- Simplifying complex neurodegenerative diseases by gene chip analysis / Scherzer, C.R.; Gullans S.R.; Jensen, R.V. -- Molecular pathology of dementia: emerging treatment strategies / Gouras, G.K. -- Expanding the role of deep brain stimulation from movement disorders to other neurological disorders / Leone, M. ... [et al.] -- Molecular mediators of pain / Chaudhary P.; Burchiel, K. -- Gene transfer in the treatment of pain / Fink, D.; Mata, M.; Glorioso, J.C. -- Gene discovery underlying stroke / Barone, F.C.; Read, S.J. -- Molecular mediators of hemorrhagic stroke / Macdonald, R.L. -- Advances towards cerebrovascular gene therapy / Watanabe, Y.; Heistad, D.D. -- Ex vivo gene therapy and cell therapy for stroke / Kondziolka, D.; Sheehan, J.; Niranjan, A. -- Neurosurgical applications for polymeric drug delivery systems / Wang, P.P.; Brem, H. -- Immunotherapy strategies for treatment of malignant gliomas / Harshyne, L.; Flomenberg, P.; Andrews, D.W. -- 'Glioma-genesis': signaling pathways for the development of molecular onco-therapy / Kapoor, G.S.; O'Rourke, D.M. -- Oncolytic viral therapy for glioma / Lamfers, M.L.M.; Visted, T.; Chiocca, E.A. -- Molecular neurosurgery in the pituitary gland: gene transfer as adjunctive treatment strategy -- Castro, M.G. ... [et al.] -- Stem cells for targeting CNS malignancy / Yip, S.; Sidman, R.L.; Snyder, E.Y.
  • Selecting the right targets for cancer therapy / Miguel H. Bronchud -- Clinical importance of prognostic factors: moving from scientifically interesting to clinically useful / N. Lynn Henry and Daniel F. Hayes -- Genetic markers in sporadic tumors / Elena Tamborini ... [et al.] -- Genetic markers in breast tumors with hereditary predisposition / Tatyana A. Grushko and Olufunmilayo I. Olopade -- Circulating tumor markers / Alan Horwich and Gill Ross -- Antibody-based proteomics analysis of tumor cell signaling pathways / Steven Pelech and Hong Zhang -- Gene expression arrays for pathway analysis in cancer research / Xiang Sean Yu ... [et al.] -- Signaling pathways in cancer / Daniel Kalderon -- Estrogen receptor pathways and breast cancer / Jing Peng and V. Craig Jordan -- Cyclin-dependent kinases and their regulators as potential targets for anticancer therapeutics / Marcos Malumbres -- Angiogenesis switch pathways / Jaume Piulats and Francesc Mitjans -- Apoptosis pathways and new anticancer agents / Frank A.E. Kruyt, Jose A. Rodriguez, and Giuseppe Giaccone -- Genomic instability, DNA repair pathways and cancer / Gabriel Capellá, Josep Balart, and Miquel Angel Peinado -- Epigenomics and cancer / Isabel Lopéz de Silanes and Manel Esteller -- Harnessing the power of immunity to battle cancer: Much ado about nothing or All's well that ends well? / Angelo A. Cardoso -- Aurora Kinases: a new target for anticancer drug development / Teresa Macarulla, Francisco Javier Ramos, and Josep Tabernero -- Emerging molecular therapies: drugs interfering with signal transduction pathways / Alison H.M. Reid, Richard Baird, and Paul Workman -- Suicide gene therapy / Silke Schepelmann, Ion Niculescu-Duvaz, and Caroline J. Springer -- Genotypes that predict toxicity and genotypes that predict efficacy of anticancer drugs / Rosario García-Campelo ... [et al.] -- A personal account of the chemoprevention of breast cancer: possible or not possible? / V. Craig Jordan.
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  • Principles of neural coding 2013, CRCnetBASE
    Understanding how populations of neurons encode information is the challenge faced by researchers in the field of neural coding. Focusing on the many mysteries and marvels of the mind has prompted a prominent team of experts in the field to put their heads together and "fire up" a book on the subject. Simply titled Principles of Neural Coding, this book covers the complexities of this discipline. It centers on some of the major developments in this area and presents a complete assessment of how neurons in the brain encode information. The book's collaborators contribute various chapters that describe results in different systems (visual, auditory, somatosensory perception, etc.) and different species (monkeys, rats, humans, etc.). The introductory chapters concentrate on the recording and analysis of the firing of single and multiple neurons as well as the analysis and recording of other integrative measures of network activity and network states, such as local field potentials or current source densities. The book then moves forward with a description of the principles of neural coding for different functions and in different species and concludes with theoretical and modeling works describing how information processing functions are implemented. The text not only contains the most important experimental findings, but gives an overview of the main methodological aspects for studying neural coding. In addition, the book describes alternative approaches based on simulations with neural networks and in silico modeling in this highly interdisciplinary topic. It can serve as an important reference to students and professionals.
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    "The fifth edition has been completely updated to reflect the tremendous amount of new research and development in neuroscience in the last decade. Lead author Eric Kandel was awarded the Nobel Prize in Physiology or Medicine in 2000"--Provided by publisher.
  • Fulltext ClinicalKey
    Part 1.General Overview . Landmarks in the History of Neurosurgery / James Tait Goodrich ; Clinical Evaluation of the Nervous System / Gerald A. Grant, Richard G. Ellenbogen ; Principles of Modern Neuroimaging / Kathleen R. Tozer Fink, Michael R. Levitt, James R. Fink ; Principles of Surgical Positioning / Genèvieve Lapointe, Joanna Kemp, Govind Rajan, Grace Elisabeth Walter, Saleem I. Abdulrauf. -- Part 2.Pediatric Neurosurgery. Spinal Dysraphism and Tethered Spinal Cord / Leslie N. Sutton, Joel A. Bauman, Luke J. Macyszyn ; Hydrocephalus in Children and Adults / Alia Hdeib, Alan R. Cohen ; Developmental Anomalies: Arachnoid Cysts, Dermoids, and Epidermoids / David F. Jimenez, Jennifer Gentry Savage, Mical Samuelson ; Diagnosis and Surgical Options for Craniosynostosis / Mitchel Seruya, Suresh N. Magge, Robert F. Keating ; The Chiari Malformations and Syringohydromyelia / R. Shane Tubbs, Todd C. Hankinson, John C. Wellons, III ; Posterior Fossa and Brainstem Tumors in Children / Adrienne Weeks, Aria Fallah, James T. Rutka ; Causes of Nontraumatic Hemorrhagic Stroke in Children: Pediatric Moyamoya Syndrome / Edward R. Smith, R. Michael Scott. -- Part 3.Vascular Neurosurgery. Cerebrovascular Occlusive Disease and Carotid Surgery / Geoffrey Appelboom, Matthew Piazza, E. Sander Connolly, Jr. ; Intracranial Aneurysms / Christopher S. Eddleman, Christopher C. Getch, Bernard R. Bendok, H. Hunt Batjer ; Vascular Malformations (Arteriovenous Malformations and Dural Arteriovenous Fistulas) / Ghaus M. Malik, Sandeep S. Bhangoo ; Cavernous Malformations Management Strategies / Aimee Two, Ali K. Ozturk, Murat Gunel ; Spontaneous Intracerebral Hemorrhage / Alan Hoffer, Justin Singer, Nicholas C. Bambakidis, Warren Selman ; Endovascular Neurosurgery / Sabareesh K. Natarajan, Adnan H. Siddiqui, L. Nelson Hopkins, Elad I. Levy ; Cerebral Revascularization for Giant Aneurysms of the Transitional Segment of the Internal Carotid Artery / Jonathon J. Lebovitz, Jorge L. Eller, Justin M. Sweeney, Deanna Sasaki-Adams, Aneela Darbar, Sheri K. Palejwala, Anja-Maria Radon, Saleem I. Abdulrauf. -- Part 4.Trauma. Intracranial Hypertension / Ryan Morton, Richard G. Ellenbogen ; Closed Head Injury / Clifford M. Houseman, Shawn A. Belverud, Raj K. Narayan ; Penetrating Brain Injury / Michael Cirivello, Randy S. Bell, Rocco A. Armonda ; Traumatic Skull and Facial Fractures / Fred H. Geisler, Eduardo Rodriguez, Paul N. Manson. -- Part 5.Spine. Injuries to the Cervical Spine / M. Yashar S. Kalani, Aristotelis S. Filippidis, Nicholas Theodore ; Thoracolumbar Spine Fractures / Edward M. Marchan, George M. Ghobrial, James S. Harrop ; Intradural Extramedullary and Intramedullary Spinal Cord Tumors. / Michaël Bruneau, Florence Lefranc, Danielle Balériaux, Jacques Brotchi ;Treatment of Spinal Metastatic Tumors / Ilya Laufer, Marcella A. Madera, Daniel Sciubba, Ziya L. Gokaslan ; Spinal Cord Injury / David W. Cadotte, Michael G. Fehlings ; Syringomyelia / Spyros Sgouros ; Craniovertebral Junction: A Reappraisal / Atul Goel ; Degenerative Spine Disease / James K.C. Liu, Edward C. Benzel ; Pediatric and Adult Scoliosis / David W. Polly, Jr., A. Noelle Larson (Part I) Frank Schwab, Benjamin Blondel, Virginie Lafage (Part II) ; Acute Nerve Injuries / Lynda J-S Yang ; Entrapment Neuropathies / Mikhail Gelfenbeyn, Henry Marsh. -- Part 6.Tumors. Low-Grade and High-Grade Gliomas / Nader Sanai, Mitchel S. Berger ; Metastatic Brain Tumors / Juanita M. Celix, Daniel L. Silbergeld ; Meningiomas / Federico Landriel, Peter Black ; Tumors of the Pineal Region / Christian Matula ; Cerebellopontine Angle Tumors / Madjid Samii, Venelin M. Gerganov ; Craniopharyngiomas and Suprasellar Tumors / Juraj ten¿o ; Pituitary Tumors: Diagnosis and Management / Carrie R. Muh, Nelson M. Oyesiku ; Endoscopic Approaches to Ventricular Tumors and Colloid Cysts / Scott D. Wait, Charles Teo ; Microsurgical Approaches to the Ventricular System / Timothy H. Lucas, II, Richard G. Ellenbogen ; Skull Base Approaches / Salvatore Di Maio, Laligam N. Sekhar ; Endoscopic Approaches to Skull Base Lesions, Ventricular Tumors, and Cysts / Nancy McLaughlin, Daniel M. Prevedello, Daniel Kelly, Ricardo L. Carrau, Amin B Kassam, Scott D. Wait, Charles Teo, Aneela Darbar, Sheri K. Palejwala. -- Part 7.Radiosurgery. Application of Current Radiation Delivery Systems and Radiobiology / Jay Loeffler, Helen Shih, Melin Khandekar ; Radiosurgery of Central Nervous System Tumors / Douglas Kondziolka, Ajay Niranjan, L. Dade Lunsford, John C. Flickinger ; Stereotactic Radiosurgery of Vascular Malformation / Chun Po Yen, Chris Cifarelli, David Schlesinger, Jason P. Sheehan. -- Part 8.Functional/Pain. Trigeminal Neuralgia / Gerald A. Grant, John D. Loeser ; Surgical Therapy for Pain / Giovanni Broggi, Francesco Acerbi, Morgan Broggi, Giuseppe Messina / Spasticity: Classification, Diagnosis, and Management / Michael R. Levitt, Samuel R. Browd ; Surgery for Temporal Lobe Epilepsy / Jeffrey G. Ojemann, Carlo Giussani, Carlo Marras ; Extratemporal Procedures and Hemispherectomy for Epilepsy / Gwyneth Hughes, William Bingaman ; Basic Principles of Deep Brain Stimulation for Movement Disorders, Neuropsychiatric Disorders, and New Frontiers / Alexander S. Taghva, Chima O. Oluigbo, Ali R. Rezai. -- Online only: E44 Minimal Access Skull Base Approaches / Paolo Cappabianca, Isabella Esposito, Luigi Maria Cavallo, Felice Esposito, Vita Stagno.
  • 1. Introduction to the Operating Room -- 2. Anatomy of Intraoperative Monitoring -- 3. Cellular Neurophysiology -- 4. Electrophysiology and Bioinstrumentation -- 5. Anesthesiology and Intraoperative Electrophysiological Monitoring -- 6. Somatosensory Evoked Potential Monitoring -- 7. Motor Evoked Potentials -- 8. Electromyography (EMG) -- 9. Brainstem Auditory Evoked Potentials -- 10. Electroencephalography -- 11. The H-Reflex and F-Response -- 12. Monitoring Procedures of the Spine -- 13. Intraoperative Monitoring for Surgery of the Spinal Cord and Cauda Equina -- 14. Monitoring Posterior Fossa Craniotomies -- 15. Intraoperative Monitoring for Carotid Endarterectomy -- 16. Monitoring for ENT Procedures -- 17. Peripheral Nerve Monitoring -- 18. Intraoperative Cortical Mapping: Basic Concepts, Indications, and Anesthesia Considerations -- 19. Neurological Assessment and Correlation in Spinal Cord Nerve Root Pathology -- 20. Electrophysiological Assessment of Spinal Cord Pathology in Pain Medicine -- 21. Spinal Cord Stimulation: Principles and Applications -- 22. New Vistas: Small-Pain-Fibers Method of Testing for Spinal Cord Assessment in Pain States.
  • Introduction and theoretical foundations / Sara A. Lawless, Julie K. Ries, and Antolin M. Llorente -- American population estimates, trends in American immigration, and neuropsychology : influences on assessment and inferential processes with Hispanic populations / Antolin M. Llorente -- Hispanic populations : special issues in neuropsychology / Antolin M. Llorente -- Intellectual abilities : theoretical and applied assessment considerations / Christian von Thomsen, Lori Gallup, and Antolin M. Llorente -- Language : development, bilingualism, and abnormal states / Christine French and Antolin M. Llorente -- The neuropsychological assessment of the Hispanic client / Antolin M. Llorente and Deborah Weber -- Hispanics and cultural bias : test development and applications / Peter Smith, Eric Lane, and Antolin M. Llorente -- Rehabilitation / Julie K. Ries, Brian Potter, and Antolin M. Llorente.
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  • The versatility of oocyte and embryo donation has proven to be extremely valuable to both patients and doctors engaged in reproductive medicine. Originally thought to be applicable only to a rather small subset of infertile women, today busy practices commonly recommend the procedure and it is estimated that nearly all of the 400 or more IVF programs in the United States provide these services. Oocyte and embryo donation has established itself as a mainstay procedure within assisted reproductive care, and the breadth, depth and complexity of practice is deserving of focused attention. Much has changed within the field of oocyte and embryo donation since the publication of the first edition of Principles of Oocyte and Embryo Donation in 1998, thus the need for a completely updated and more expansive text. The second edition of this book provides an overview of the major issues affecting men and women engaged in the practice of oocyte and embryo donation. A primary emphasis has been placed on defining the standards of practice that have evolved over the past 30 years, clearly stating the outcomes expected from adhering to these established protocols. Details of both the basic science and the clinical medicine are presented together and attention is also focused on the non-reproductive aspects inherent to this unique method of assisted reproduction that involves opinions from lawyers, ethicists, mental health care professionals and theologians. Oocyte and embryo donation requires a working knowledge of the medicine, the law and the ethics that underlies its foundation. This book is intended to serve as a complete and comprehensive reference for all health care professionals that provide services related to egg donation, reproductive endocrinologists, obstetrician- gynecologists, and fellows and residents entering the fertility field.
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    This edition provides a balanced presentation of theory and observation. It introduces the principles of genetics and statistics that are relevant to population studies, and examines the forces affecting genetic variation from the molecular to the organismic level.
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    Concepts and definitions of public health practice / F. Douglas Scutchfield and C. William Keck -- History and development of public health / Elizabeth Fee -- Emergence of a new public health / C. William Keck and F. Douglas Scutchfield -- Social determinants of health : their influence on personal choice, environmental exposures, and health care / Steven H. Woolf and Robert L. Phillips, Jr. -- Public health policy and the policy-making process / Thomas C. Ricketts -- The legal basis for public health practice / Edward P. Richard III and Kahterine C. Rathbun -- Public health ethics / James C. Thomas -- The federal contribution to public health / William L. Roper -- The state public health agencies / A. Richard Melton and Laverne Alves Snow -- The local health department / Carolyn J. Leep, Grace Gorenflo, and Patrick M. Libbey -- Epidemiology and public health data / Donna F. Stroup and Stephen B. Thacker -- Community health planning and programming / Laura H. Downey and F. Douglas Scutchfield -- Prevention effectiveness / Kakoli Roy, Zhuo Chen, and Anne Haddix -- Behavioral community health needs assessment / John Elder, Paula M. Usita, and Noé Crespo -- The management of public health organizations / Julia F. Costich and J. Michael Moser -- Performance measurement and management in public health / Paul K. Halverson -- Public health workforce / Patricia M. Sweeney, Kristine M. Gebbie, and Hugh Tilson -- Leadership in public health practice / Cynthia D. Lamberth and Louis Rowitz -- Chronic disease control / Janet Collins, Linnea Evans and David V. McQueen -- Reducing tobacco use / Michael P. Eriksen and Lawrence W. Green -- Drug and alcohol issues in public health / C.G. Leukefeld ... [et al.] -- Infectious disease control / Alan R. Hinman -- Public health preparedness / Linda Young Landesman, Isaac B. Weisfuse, and Susan Waltman -- Environmental health in public health / Alan M. Jacobs and DuWayne Porter -- Primary care and public health / Michael R. King, Kevin A. Pearce, and Samuel C. Matheny -- Maternal and child health / Carol Hogue -- Injury control / María Seguí-Gómez and Susan P. Baker -- Oral diseases : the neglected epidemic / Myron Allukian Jr. -- The public health laboratory / Ronald L. Cada and Ralph Timperi -- Global health / Alfredo E. Vergara and Sten H. Vermund -- The future of public health / C. William Keck and F. Douglas Scutchfield.
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  • Principles of Pulmonary Medicine helps you master the foundations of pulmonary medicine without being overwhelmed! This concise, easy-to-read medical reference book correlates basic science principles with the radiologic, pathologic, and clinical aspects of respiratory disease to provide an integrated, accessible approach to the study of pulmonary medicine. Focus on the clinical aspects and treatment of specific pulmonary and respiratory diseases, and understand the anatomy, physiology, and pathophysiology relevant to major pulmonary disorders.Apply the material to real-life practice with case-based pulmonology questions covering topics including pulmonary function tests, physiologic data, and results of arterial blood gas testing.
  • Anatomy of the lungs -- Respiratory physiology -- Histological features of lungs -- Cellular and molecular aspects of lung function, its control and regulation -- Imaging evaluation of the thorax -- Endothelial protection during heart surgery and lung transplantation -- Vascular endothelial growth factor and pulmonary injury -- Aprotinin decreases lung reperfusion injury and dysfunction -- Effects of prostaglandin E1 and nitroglycerin on lung preservation -- Endothelin and ischemia-reperfusion injury -- L-arginine and ischemia-reperfusion injury -- The role of nitric oxide in pulmonary ischemia-reperfusion injury -- Activity of glutathione-related enzymes in ischemia and reperfusion injury -- Heart histopathology in ischemia-reperfusion injury -- Beating heart surgery and pulmonary ischemia and reperfusion injury -- Mechanisms of pulmonary edema -- Idiopathic pulmonary hypertension: new challenges -- Chronic thromboembolic pulmonary hypertension and pulmonary endarterectomy -- Eisenmenger syndrome -- Disseminated intravascular coagulation in cardiac surgery -- Pulmonary arterial hypertension -- The extracorporeal circulation circuit versus bioengineering biomaterials -- Ischemic preconditioning and lung preservation -- Impact of cardiopulmonary bypass on pulmonary hemodynamic variables -- Impact of cardiopulmonary bypass on gas exchange features -- Pulmonary energy metabolism and multiple inflammatory repercussions -- Benefits of ultrafiltration for pulmonary function -- Principles of pulmonary protections during heart surgery: benefits of hemofiltration for pulmonary function -- Determining hemodynamic parameters -- Extracorporeal circuit pathways for lung perfusion -- Hemodynamic performance -- Quality of gas exchange -- Inflammatory cell markers -- Cytokines and cellular adhesion molecules -- Macroscopical and microscopical findings -- Continuous or intermittent lung perfusion with arterial or venous blood -- Lung perfusion and mechanical ventilation -- Pulmonary hemodynamic profile and natriuretic peptides -- Low-frequency mechanical ventilation during cardiopulmonary bypass -- Inhaled carbon monoxide as an experimental therapeutic strategy of lung protection during cardiopulmonary bypass -- Lung perfusion and coronary artery bypass grafting -- Lung perfusion in clinical mitral valve surgery -- Lung perfusion in clinical aortic surgery -- Lung perfusion in clinical heart-lung surgery: congenital heart disease surgery -- Retrograde pulmonary perfusion for pulmonary thromboembolism -- Lung perfusion in clinical heart-lung transplantation -- Principles of pulmonary protection during heart surgery -- Lung perfusion: reflections and perspectives.
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  • Fulltext ClinicalKey
    Chapter 1. Molecular Organization of Cells / Jon D. Ahlstrom -- Chapter 2. Cell-ECM Interactions in Repair and Regeneration / M. Petreaca, M. Martins-Green -- Chapter 3. Mechanisms of Blastema Formation in Regenerating Amphibian Limbs / David L. Stocum, Nandini Rao -- Chapter 4. The Molecular Circuitry Underlying Pluripotency in Embryonic Stem Cells and iPS Cells / Harvir Singh, Ali H. Brivanlou -- Chapter 5. How Cells Change their Phenotype / Caroline Beth Sangan, David Tosh -- Chapter 6. Scarless Wound Healing / Allison Nauta, Barrett Larson, Michael T. Longaker, H. Peter Lorenz -- Chapter 7. Somatic Cloning and Epigenetic Reprogramming in Mammals / Heiner Niemann, Wilfried A. Kues, Andrea Lucas-Hahn, Joseph W. Carnwath -- Chapter 8. Engineered Proteins for Controlling Gene Expression / Charles A. Gersbach -- Chapter 9. Genetic Approaches in Human Embryonic Stem Cells and their Derivatives: Prospects for Regenerative Medicine / Junfeng Ji, Bonan Zhong, Mickie Bhatia -- Chapter 10. Embryonic Stem Cells: Derivation and Properties / Junying Yu, James A. Thomson -- Chapter 11. Alternative Sources of Human Embryonic Stem Cells / Svetlana Gavrilov, Virginia E. Papaioannou, Donald W. Landry -- Chapter 12. Stem Cells from Amniotic Fluid / Mara Cananzi, Anthony Atala, Paolo de Coppi -- Chapter 13. Induced Pluripotent Stem Cells / Keisuke Okita, Shinya Yamanaka -- Chapter 14. MSCs in Regenerative Medicine / Arnold I. Caplan -- Chapter 15. Multipotent Adult Progenitor Cells / Philip Roelandt, Catherine M. Verfaillie -- Chapter 16. Hematopoietic Stem Cell Properties, Markers, and Therapeutics / Kuanyin K. Lin, Grant A. Challen, Margaret A. Goodell -- Chapter 17. Mesenchymal Stem Cells / Zulma Gazit, Gadi Pelled, Dima Sheyn, Nadav Kimelman, Dan Gazit -- Chapter 18. Cell Therapy of Liver Disease: From Hepatocytes to Stem Cells / Stephen C. Strom, Ewa C.S. Ellis -- Chapter 19. Cardiac Stem Cells: Biology and Therapeutic Applications / Sarah Selem, Konstantinos E. Hatzistergos, Joshua M. Hare -- Chapter 20. Skeletal Muscle Stem Cells / Benjamin D. Cosgrove, Helen M. Blau -- Chapter 21. Stem Cells Derived from Fat / Adam J. Katz, Alexander F. Mericli -- Chapter 22. Peripheral Blood Stem Cells / Zhan Wang, Gunter Schuch, J. Koudy Williams, Shay Soker -- Chapter 23. Islet Cell Therapy and Pancreatic Stem Cells / Juan Domínguez-Bendala, Antonello Pileggi, Camillo Ricordi -- Chapter 24. Regenerative Medicine for Diseases of the Retina / Deepak A. Lamba, Thomas A. Reh -- Chapter 25. Somatic Cells: Growth and Expansion Potential of T Lymphocytes / Rita B. Effros -- Chapter 26. Mechanical Determinants of Tissue Development / Jonathan A. Kluge, Gary G. Leisk, David L. Kaplan -- Chapter 27. Morphogenesis of Bone, Morphogenetic Proteins, and Regenerative Medicine / A.H. Reddi -- Chapter 28. Physical Stress as a Factor in Tissue Growth and Remodeling / Joel D. Boerckel, Christopher V. Gemmiti, Yash M. Kolambkar, Blaise D. Porter, Robert E. Guldberg -- Chapter 29. Intelligent Surfaces for Cell-Sheet Engineering / Takanori Iwata, Masayuki Yamato, Teruo Okano -- Chapter 30. Applications of Nanotechnology for Regenerative Medicine / Benjamin S. Harrison, Sirinrath Sirivisoot -- Chapter 31. Design Principles in Biomaterials and Scaffolds / Hyukjin Lee, Hyun Jung Chung, Tae Gwan Park -- Chapter 32. Natural Origin Materials for Bone Tissue Engineering - Properties, Processing, and Performance / V.M. Correlo, J.M. Oliveira, J.F. Mano, N.M. Neves, R.L. Reis -- Chapter 33. Synthetic Polymers / M.C. Hacker, A.G. Mikos -- Chapter 34. Biological Scaffolds for Regenerative Medicine / Alexander Huber, Stephen F. Badylak -- Chapter 35. Hydrogels in Regenerative Medicine / Justin M. Saul, David F. Williams -- Chapter 36. Surface Modification of Biomaterials / Andrés J. García -- Chapter 37. Histogenesis in Three-dimensional Scaffolds / Melissa K. McHale, Nicole M. Bergmann, Jennifer L. West -- Chapter 38. Biocompatibility and Bioresponse to Biomaterials / James M. Anderson -- Chapter 39. Designing Tunable Artificial Matrices for Stem Cell Culture / Elizabeth F. Irwin, Jacob F. Pollock, David V. Schaffer, Kevin E. Healy -- Chapter 40. Biomineralization and Bone Regeneration / Jiang Hu, Xiaohua Liu, Peter X. Ma -- Chapter 41. Cell Therapy for Blood Substitutes / Shi-Jiang Lu, Qiang Feng, Feng Li, Erin A. Kimbrel, Robert Lanza -- Chapter 42. Articular Cartilage / Lily Jeng, Francois Ng kee Kwong, Myron Spector -- Chapter 43. Myoblast Transplantation in Skeletal Muscles / Daniel Skuk, Jacques P. Tremblay -- Chapter 44. Clinical Islet Transplantation / Juliet A. Emamaullee, Michael McCall, A.M. James Shapiro -- Chapter 45. Fetal Tissues / Ryan P. Dorin, Chester J. Koh -- Chapter 46. Engineering of Large Diameter Vessels / Masood A. Machingal, Saami K. Yazdani, George J. Christ -- Chapter 47. Engineering of Small-Diameter Vessels / Brett C. Isenberg, Chrysanthi Williams, Robert T. Tranquillo -- Chapter 48. Cardiac Tissue / Milica Radisic, Michael V. Sefton -- Chapter 49. Regenerative Medicine in the Cornea / May Griffith, Per Fagerholm, Neil Lagali, Malcolm A. Latorre, Joanne Hackett, Heather Sheardown -- Chapter 50. Alimentary Tract / Richard M. Day -- Chapter 51. Extracorporeal Renal Replacement / Kimberly A. Johnston, H. David Humes -- Chapter 52. Tissue Engineering of the Reproductive System / Stefano Da Sacco, Laura Perin, Roger E. De Filippo -- Chapter 53. Cartilage Tissue Engineering / Qiongyu Guo, Jennifer H. Elisseeff -- Chapter 54. Functional Tissue Engineering of Ligament and Tendon Injuries / Savio L.-Y. Woo, Alejandro J. Almarza, Sinan Karaoglu, Rui Liang, Matthew B. Fisher -- Chapter 55. Central Nervous System / Brian G. Ballios, M. Douglas Baumann, Michael J. Cooke, Molly S. Shoichet -- Chapter 56. Peripheral Nerve Regeneration / Mahesh C. Dodla, Vivek J. Mukhatyar, Ravi V. Bellamkonda -- Chapter 57. Tissue Engineering of Skin / Fiona Wood -- Chapter 58. Regenerative Medicine of the Respiratory Tract / Martin A. Birchall, Sam Janes, Paolo Macchiarini -- Chapter 59. The Digit: Engineering of Phalanges and Small Joints / Makoto Komura, Jaehyun Kim, Anthony Atala, James J. Yoo, Sang Jin Lee -- Chapter 60. Intracorporeal Kidney Support / Jae Hyun Bae, Tamer Aboushwareb, Anthony Atala, James J. Yoo -- Chapter 61. Ethical Considerations / Ronald M. Green -- Chapter 62. US Stem Cell Research Policy / Josephine Johnston -- Chapter 63. Overview of the FDA Regulatory Process / Kevin J. Whittlesey, Mark H. Lee, Jiyoung M. Dang, Maegen Colehour, Judith Arcidiacono, Ellen Lazarus, David S. Kaplan, Donald Fink, Charles N. Durfor, Ashok Batra, Stephen L. Hilbert, Deborah Lavoie Grayeski, Richard McFarland, Celia Witten.
  • The Body Fluids -- Essential Anatomy of the Kidney -- Glomerular Filtration -- Tubular Transport -- The Proximal Tubule -- The Loop of Henle, Distal Tubule and Collecting Duct -- Renal Blood Flow and Glomerular Filtration Rate -- Regulation of Body Fluid Osmolality -- Regulation of Body Fluid Volume -- Renal Regulation of Body Fluid pH -- Renal Control of Body Fluid Potassium Content -- Renal Regulation of Body Calcium, Magnesium and Phosphate -- Summary of the Principal Reabsorptive and Secretory Processes in the Nephron Segments -- Disease Conditions Which Alter Renal Sodium and Water Reabsorption -- Use of Diuretics.
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  • Tissue engineering in perspective -- Introduction to tissue engineering -- Basis of growth and differentiation -- In vitro control of tissue development -- In vivo synthesis of tissues and organs -- Models for tissue engineering -- Biomaterials in tissue engineering -- Transplantation of engineered cells and tissues -- Fetal tissue engineering -- Gene therapy -- Breast -- Cardiovascular system -- Cornea -- Endocrinology and metabolism -- Gastrointestinal system -- Hematopoietic system -- Kidney and genitourinary system -- Musculoskeletal system -- Nervous system -- Periodontal and dental applications -- Skin -- Womb -- Regulatory issues.
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    Introduction and definitions -- Target identification and validation -- Biomarkers -- Early clinical trial design -- Pharmaceutical toxicology -- Translational science biostatistics -- Learning by experience : examples of translational processes in the cardiovascular field.
  • Technical issues in vascular ultrasound -- Carotid artery disease and extracranial cerebrovascular disease -- Upper extremity arterial disease -- Arteriovenous fistulas -- Lower extremity arterial disease -- Catheterization-related complications -- The abdominal aorta -- Renal artery disease -- Splanchnic/mesenteric/visceral arteries -- Upper extremity venous disease -- Lower extremity venous disease.
  • Principles of virology. 3rd ed. Lane Catalog record
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    v. 1. Molecular biology -- v. 2. Pathogenesis and control. v. 1. Foundations -- The infectious cycle -- Genomes and genetics -- Structure -- Attachment and entry -- Synthesis of RNA from RNA templates -- Reverse transcription and integration -- Transcription strategies : DNA templates -- Genome replication strategies : DNA viruses -- Processing of viral pre-mRNA -- Control of translation -- Intracellular trafficking -- Assembly, exit, and maturation -- v. 2. Infection of a susceptible host -- Infection of populations -- Virus offense meets host defense : early actions -- Immune defenses -- Patterns of infection -- Human immunodeficiency virus pathogenesis -- Transformation and oncogenesis -- Vaccines -- Antiviral drugs -- Evolution and emergence.
  • This book contains a selection of chapters aimed to provide a better understanding prion structure and biology. Together these chapters provide an overview of prion biology and underscore some of the challenges we face if we want to understand how this lively pathogen propagates and evolves in mammals. There is also mounting evidence that studying prion biology has a wider relevance due to similarities in the processes of protein misfolding and aggregation between prion disorders and other neurodegenerative disorders such as Alzheimer's, Parkinson's, and Huntington's diseases.
  • Prion protein protocols 2008, Springer Protocols
    Cell culture models to unravel prion protein function and aberrancies in prion diseases / Katarina Bedecs -- Investigation of PrPc metabolism and function in live cells : methods for studying individual cells and cell populations / Cathryn L. Haigh and David R. Brown -- Immunodetection of PrPsc using western and slot blotting techniques / Hanny Gyllberg and Kajsa Löfgren -- Assaying prions in cell culture : the standard scrapie cell assay (SSCA) and the scrapie cell assay in end point format (SCEPA) / Sukhvir P. Mahal ... [et al.] -- Generation of cell lines propagating infectious prions and the isolation and characterization of cell-derived exosomes / Laura J. Vella and Andrew F. Hill -- Neurotoxicity of prion peptides on cultured cerebellar neurons / Giuseppe D. Ciccotosto, Roberto Cappai, and Anthony R. White -- Understanding the nature of prion diseases using cell-free assays / Victoria A. Lawson -- Methods for conversion of prion protein into amyloid fibrils / Leonid Breydo, Natallia Makarava, and Ilia V. Baskakov -- Amplification of purified prions in vitro / Surachai Supattapone, Nathan R. Deleault, and Judy R. Rees -- Expression and purification of full-length recombinant PrP of high purity / Natallia Makarava and Ilia V. Baskakov -- Analysis of PrP conformation using circular dichroism / Sen Han and Andrew F. Hill -- Effect of copper on the de novo generation of prion protein expressed in Pichia pastoris / Carina Treiber -- Biophysical investigations of the prion protein using electron paramagnetic resonance / Simon C. Drew and Kevin J. Barnham -- Molecular diagnosis of human prion disease / Jonathan D.F. Wadsworth ... [et al.] -- Analysis of endogenous PrPc processing in neuronal and non-neuronal cell lines / Victoria Lewis and Steven J. Collins -- Molecular typing of PrPres in human sporadic CJD brain tissue / Victoria Lewis ... [et al.] -- Transgenic mouse models of prion diseases / Glenn C. Telling -- Quantitiative bioassay of surface-bound prion infectivity / Victoria A. Lawson.
  • Transmissible spongiform encephalopathies (TSE), now broadly known as prion diseases, have been recognized for nearly 300 years in animals and almost 100 years in humans. However, the nature of the transmissible agent had largely remained a mystery until Stanley Prusiner discovered the infectious isoform of the prion protein (PrP), named prion or scrapie PrP (PrPSc), in 1982. The subsequent modern studies with protein chemistry and molecular biology in cell culture, transgenic animals, and cell-free systems, including the revolutionary protein-misfolding cyclic amplification (PMCA), have greatly advanced our understanding of the pathogenesis of prion diseases and facilitated the identification of new prion diseases in animals and humans. In Prions and Prion Diseases, more than 60 leading researchers and clinicians worldwide provide an up-to-date development in many aspects of these unique infectious pathogens and their associated diseases.Volume I highlights the association of the cellular prion protein (PrPC) with copper and zinc, the potential roles of PrPC in Alzheimer's disease and cancers, insoluble PrPC, PMCA, molecular and cellular mechanisms of PrPSc formation and clearance, possible co-factors involved in the conversion of PrPC into PrPSc, infectious and pathogenic forms of PrP, cell biology of prions, prion strains and their interference, as well as yeast prions and their inheritable and structural traits. This unique volume covers history from the high Middle Ages to the TSE era of Daniel Carleton Gajdusek, followed by the prion era of Stanley Prusiner whose extraordinary discovery opened a new chapter in prion research. Volume I will take you through the fascinating chronicle of prions in mammals, yeast, and fungi.
  • Transmissible spongiform encephalopathies (TSE), now broadly known as prion diseases, have been recognized for nearly 300 years in animals and almost 100 years in humans. However, the nature of the transmissible agent had largely remained a mystery until Stanley Prusiner discovered the infectious isoform of the prion protein (PrP), named prion or scrapie PrP (PrPSc), in 1982. The subsequent modern studies with protein chemistry and molecular biology in cell culture, transgenic animals, and cell-free systems, including the revolutionary protein-misfolding cyclic amplification (PMCA), have greatly advanced our understanding of the pathogenesis of prion diseases and facilitated the identification of new prion diseases in animals and humans. In Prions and Prion Diseases, more than 60 leading researchers and clinicians worldwide provide an up-to-date development in many aspects of these unique infectious pathogens and their associated diseases.Volume II features a variety of animal and human prion diseases, including the newly-identified atypical forms of bovine spongiform encephalopathy and scrapie in animals, and variably protease-sensitive prionopathy in humans, prions in the environment, Tau pathology in human prion disease, transmission of the disease by blood transfusion, mammalian and non-mammalian models, conventional and advanced diagnoses, prion-specific antibodies, as well as decontamination of prions and development of therapeutics of prion diseases, such as the application of immunomodulation. This volume provides up-to-date knowledge about the etiology, pathogenesis, classification, histopathological, and clinical aspects of the highly publicized animal and human prion diseases.
  • Prions in humans and animals Lane Catalog record
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    Ch. 1. Caring for the critically ill patient -- Ch. 2. Ethical and legal issues -- Ch. 3. Patient and family education -- Ch. 4. Psychosocial alterations -- Ch. 5. Sleep alterations -- Ch. 6. Nutritional alterations -- Ch. 7. Gerontologic alterations -- Ch. 8. Pain and pain management -- Ch. 9. Sedation, agitation, and delirium management -- Ch. 10. End-of-life care-- Ch. 11 Cardiovascular assessment and diagnostic procedures -- Ch. 12. Cardiovascular disorders -- Ch. 13. Cardiovascular therapeutic management -- Ch. 14. Pulmonary assessment and diagnostic procedures -- Ch. 15. Pulmonary disorders -- Ch. 16. Pulmonary therapeutic management -- Ch. 17. Neurologic assessment and diagnostic procedures -- Ch. 18. Neurologic disorders and therapeutic management -- Ch. 19. Renal assessment and diagnostic procedures -- Ch. 20. Renal disorders and therapeutic management -- Ch. 21. Gastrointestinal assessment and diagnostic procedures -- Ch. 22. Gastrointestinal disorders and therapeutic management -- Ch. 23. Endocrine assessment and diagnostic procedures -- Ch. 24. Endocrine disorders and therapeutic management -- Ch. 25. Trauma -- Ch. 26. Shock and multiple organ dysfunction syndrome -- Ch 27. Hematologic and oncologic issues.
  • Background -- Scope, goal, objectives and target audience -- Global burden of NCDs -- Role of research in the implementation of the Global Strategy Action Plan -- Need for a prioritized research agenda for prevention and control of major NCDs to improve public health -- Achievable outcomes through a prioritized research agenda for prevention and control of major NCDs -- Process for the development of the WHO NCD research agenda. Initial phase of development of the WHO NCD research agenda -- Ranking process -- Finalization of WHO NCD research agenda -- Key domains for research. Major NCDs. Cardiovascular disease (CVD) -- Cancer -- Chronic respiratory diseases -- diabetes -- NCD risk factors. Tobacco control -- Nutrition, physical activity and obesity -- Cross-cutting domains. Primary health care approach for prevention and control of NCDs -- Social determinants and NCDs -- Genetics -- Promoting use of research findings to policies and practice for prevention and control of noncommunicable diseases -- Top 20 priority areas for NCD research -- Key elements required for strengthening the research capacity of low- and middle-income countries for implementation of the WHO NCD research agenda. Contents of the compact disc: -- 1. Working papers -- 2. Reports of Meetings to develop the Prioritized NCD research agenda (2008-2010) -- 3. Lists of participants -- 4. List of other contributors and institutions that participated in the process of development and review of the prioritized NCD research agenda.
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    "In Private Bodies, Public Texts, Karla FC Holloway examines instances where medical issues and information that would usually be seen as intimate, private matters are forced into the public sphere. As she demonstrates, the resulting social dramas often play out on the bodies of women and African Americans..."--P. [2] of cover.
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    The authority of a scientific doctor -- Organizing a private office : between home and hospital -- The diagnosis of hidden disease -- Treatment : how to know what works -- Nervous disease and personal identity -- Medical care for the dying, in principle and in fact -- From Cabot's day to ours.
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  • A leisurely look at statistical inference / Dirk Husmeier -- Introduction to learning Bayesian networks from data / Dir Husmeier -- A casual view of multi-layer perceptrons as probability models / Richard Dybowski -- Introduction to statistical phylogenetics / Dirk Husmeier -- Detecting recombination in DNA sequence alignments / Dirk Husmeier, Frank Wright -- RNA-based phylogenetic methods / Magnus Rattray, Paul G. Higgs -- Statistical methods in microarray gene expression data analysis / Claus-Dieter Mayer, Chris A. Glasbey -- Inferring genetic regulatory networks from microarray experiments with Bayesian networks / Dirk Husmeier -- Modeling genetic regulatory networks using gene expression profiling and state-space models / Claudia Rangel ... [et al.] -- An anthology of probabilistic models for medical informatics / Richard Dybowski, Stephen Roberts -- Bayesian analysis of population pharmacokinetic/pharmacodynamic models / David J. Lunn -- Assessing the effectiveness of Bayesian feature selection / Ian T. Nabney ... [et al.] -- Bayes consistent classification of EEG data by approximate marginalization / Peter Sykacek, Iead Rezek, and Stephen Roberts -- Ensemble hidden Markov models with extended observation densities for biosignal analysis / Iead Rezek, Stephen Roberts -- A probabilistic network for fusion of data and knowledge in clinical microbiology / Steen Andreassen ... [et al.] -- Software for probability models in medical informatics / Richard Dybowski.
  • Probability and statistics with R SU Catalog (SearchWorks)
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  • Probiotics : definition and taxonomy 10 years after the FAO/WHO guidelines / L. Morelli -- Intestinal microbiota composition in children / V. Buccigrossi -- Intestinal microbiota composition in adults / V. Robles-Alonso, F. Guarner -- The intestinal microbiota and aging / P.W. O'Toole, P. Brigidi -- Shaping intestinal bacterial community by TLR and NLR signaling / K.S. Kobayashi -- Importance of early microbial colonization for intestinal immune development / P. Brandtzaeg -- Effects of the intestinal microbiota on behavior and brain biochemistry / E. Barrett ... [et al.] -- Relationship between bacterial colonization of human digestive and respiratory tract / S.V. Lynch -- Probiotics in the prevention and treatment of inflammatory bowel diseases in children / B. Pigneur, F.M. Ruemmele -- Functional gastrointestinal disorders in children / F. Indrio, G. Fiezzo -- Functional gastrointestinal disorders in adults / E.M.M. Quigley -- Metabolic syndrome and obesity in children / R. Luoto ... [et al.] -- Metabolic syndrome and obesity : adults / S.E. Power ... [et al.] -- Neonatal necrotizing enterocolitis / J. Neu -- Role of probiotics in allergies / R.B. Canani ... [et al.] -- Probiotics in respiratory infections / E. Bruzzese, A. Lo Vecchio, E. Ruberto -- Are probiotic effects dose-related? / T.J. Patton, S. Guandalini -- Safety of probiotics / I. Hojsak, R. Shamir -- Age-related functional feeding : a novel tool to improve the quality of life / S. Forssten ... [et al.] -- Use of microbes to fight microbes / C. Hill -- What is the future for therapies derived from the microbiome (pharmabiotics)? / G.T. Rijkers ... [et al.].
  • 1. Probiotics, prebiotics and synbiotics : an introduction / Ravinder Nagpal, Hariom Yadav, Manoj Kumar, Shalini Jain, Yuichiro Yamashiro and Francesco Marotta -- 2. Sources, production and microencapsulation of probiotics / Dima Stefan, Bahrim Gabriela Elena and Iordachescu Gabriela -- 3. Sources and production of prebiotics / Linglin Fu and Yanbo Wang -- 4. Analysis of probiotics and prebiotics / Semih Otles and V. Hazal Ozyurt -- 5. Regulation and guidelines of probiotics and prebiotics / Arturo Anadn̤, Vc̕tor Castellano and Mara̕ Rosa Martn̕ez-Larraąga -- 6. Probiotics and prebiotics in infant nutrition / Dan W. Thomas and Vivien A. Nguyen -- 7. Probiotics and prebiotics in lipid metabolism / Derya Koȧk Yan?k, Ay?e Binnur Erba?c? and Fahrettin G?̲¿? -- 8. Pro- and prebiotics for elderly / Lyra A., Tiihonen K., Lehtinen M.J. and Ouwehand A.C. -- 9. Probiotics and prebiotics in animal nutrition / Mattarelli Paola, Modesto Monica, Sgorbati Barbara and Tacconi Stefano -- 10. Interactions of probiotics and prebiotics with minerals / Corrie M. Whisner and Connie M. Weaver -- 11. Probiotics and prebiotics in obesity and energy metabolism / Ay?e Binnur Erba?c? -- 12. Probiotics and prebiotics and the gut microbiota / Eamonn M.M. Quigley -- 13. Probiotics and prebiotics in immune system protection / Esther Nova, Cristina Abad, Sonia Gm̤ez-Martn̕ez, Tamara Pozo-Rubio and Ascensin̤ Marcos -- 14. Probiotics and prebiotics in pediatric diarrheal disorders / Y. Vandenplas, B. Hauser, E. De Greef, T. Devreker and G. Veereman-Wauters -- 15. Probiotics for gastrointestinal diseases / Hale Akp?nar -- 16. Probiotics and helicobacter pylori / Ruggiero Francavilla, Mari Elena Tripaldi, Massimiliano Praitano, Elena Lionetti and Vito Leonardo Miniello -- 17. Probiotics and prebiotics in infections / Shigeru Kamiya -- 18. Probiotics and prebiotics in cancer prevention / Vijaya K. Gogineni and Lee E. Morrow -- 19. Probiotics and prebiotics in allergy and asthma / Bengt Bjr̲kstň -- 20. Probiotics and prebiotics in Crohn's disease / Susan Mikolaitis, Prachi Chakradeo and Ece A. Mutlu -- 21. Probiotics and prebiotics : new hope for genitourinary health / Sarika Amdekar, Avnish Kumar, Vivek Kumar Shrivastav, Desh Deepak Singh and Vinod Singh -- 22. Genomics of probiotics and prebiotics / Daniel J. O'Sullivan and Prakash M. Halami -- 23. The future of prebiotics and probiotics / Oscar Brunser, Javier A. Bravo and Martin Gotteland.
  • "Written by international experts, this book reviews recent, cutting-edge research on the use of immunoregulatory probiotics (immunobiotics) and their bioactive compounds (immunogenics) to prevent and improve health. Each chapter provides critical insight, reviews current research, discusses future perspective, and stimulates discussion. The book also dicsusses novel applications of immunobiotics such as their use in respiratory infections, regulation of the interaction between inflammation and coagulation as well as their effect on hematopoiesis"--Provided by publisher.
  • Problem based urology 2013, Springer
    Urological problems are so common as to represent a significant burden for many primary care physicians and GPs in their everyday practice worldwide. A major concern is how far to go themselves in the diagnosis and treatment of a urological diseases and when to refer the patient for specialist care. Problem Based Urology provides an easy and user-friendly tool to assist in decision making in the treatment of the more common urological problems and the most appropriate timing for referral to specialist care. Within each chapter, one or more flow charts are included to help the reader to formulate the most likely diagnosis on the basis of findings from medical history, examination and investigations, and to start an appropriate first-line treatment or to refer the patient to the specialist where appropriate. This book will appeal to the primary care physician or general practitioner and is an invaluable reference for professionals dealing with common urological complaints.
  • Elsevier's new Problem Solving in Abdominal Imaging offers you a concise, practical, and instructional approach to your most common imaging questions. It presents basic principles of problem solving to apply to imaging the abdominal and pelvic organs, gastrointestinal tract, and genitourinary tract. Inside, you₂ll find expert guidance on how to accurately read what you see, and how to perform critical techniques including biopsy and percutaneous drainage. User-friendly features, such as tables and boxes, tips, pitfalls, and rules of thumb, place today's best practices at your fingertips. A full-color design, including more than 700 high-quality images, highlights critical elements and compliments the text, to enhance your understanding. Best of all, a bonus CD provides you with an atlas of basic surgical procedures and survival guides for managing musculoskeletal and chest findings encountered on abdominal imaging examinations. Provides problem-solving advice to help you find abnormalities and accurately identify what you see. Presents a section devoted to clinical scenarios - organized by presenting signs or disease processes - covering those you₂re most likely to encounter in daily practice. Includes tips for optimization of the most common advanced imaging techniques used for the abdominal and pelvic regions- with general indications for use and special situations--to help you make the most of each modality. Offers step-by-step guidance that will help you safely approach challenging abdominal interventions, reduce complications, and improve outcomes. Features tables and boxes, tips, pitfalls, and other teaching points for easy reference. Incorporates high-quality images and a full-color design that illuminate important elements.
  • Problem solving in diabetes Lane Catalog record
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  • Strategies for reducing radiation exposure from MDCT in the acute care setting / Aaron D. Sodickson -- Image management in emergency radiology / Martin Lee Gunn -- Craniocerebral trauma / Wayne Scott Kubal -- Non-traumatic brain emergencies / Wayne Scott Kubal -- Face and neck emergencies / Wayne Scott Kubal -- Spinal trauma / Wayne Scott Kubal -- Non-traumatic spine emergencies / Thomas Ptak -- Blunt chest trauma / Lisa A. Miller and Stuart E. Mirvis -- Nonvascular chest emergencies / Jamlik-Omari Johnson, Anuj Tewari and Waqas Shuaib -- Vascular chest emergencies / Sanjeev Bhalla -- Blunt abdominal and retroperitoneal trauma / Kathirkamunathan shanmuganathan -- Imaging of penetrating trauma of the torso and / Kathirkamunathan shanmuganathan -- Non-traumatic abdominal emergencies / Jorge Soto and Kathirkamunathan shanmuganathan -- Upper extremity / Joseph S. Yu -- Lower extremity / Joseph S. Yu -- Pelvis / Joseph S. Yu -- Emergent soft tissue conditions / Joseph S. Yu.
  • The 5th Edition, by James L. Gutmann and Paul Lovdahl, offers updated techniques and an evidence-based approach to the most common procedures performed at chairside. Ideal for both endodontists and general dentists, this thoroughly revised reference combines the precision of quality endodontic care with achievable and pain-free outcomes for the patient. Each chapter has been carefully designed so that you'll quickly grasp the anatomy, the instruments needed, and what procedures should be performed -- all supplemented by boxed clinical case examples and tips. Going beyond problem solving, it also addresses the major issues in diagnostic, anatomic, restorative, periodontic, traumatic, and surgical aspects of tooth retention. Provides a practical, problem-solving approach with new chapters on: radiographic technique and interpretation; impact of pulp disease on the periodontium and vice versa; treatment failure and tooth retention; how to differentiate problems of pulp/periodontium from those that are non-odontogenic in nature; vital pulp therapy; and more.
  • Elsevier's 'Problem Solving in Radiology' series offers an instructional approach to common imaging questions. In this musculoskeletal volume, readers will find guidance on how to accurately read what they see and how to perform common office procedures, including arthrography and biopsy.
  • A survival guide to solving diagnostic challenges that are particularly problematic in neuroimaging. With a concise, practical, and instructional approach, it helps apply basic principles of problem solving to imaging of the head and interventional neck, brain, and spine. Inside, you'll find expert guidance on how to accurately read what you see, and how to perform critical techniques including biopsy, percutaneous drainage, and tumor ablation. User-friendly features, such as tables and boxes, tips, pitfalls, and rules of thumb, place today's best practices at your fingertips, including protocols for optimizing the most state-of-the-art imaging modalities. A full-color design, including more than 700 high-quality images, highlights critical elements to enhance your understanding. Apply expert tricks of the trade and protocols for optimizing the most state-of-the-art imaging modalities and their clinical applications used for the brain and spine-with general indications for use and special situations. Make the most efficient use of modern imaging modalities including multidetector CT, PET, advanced MR imaging/MR spectroscopy (MRS), diffusion-weighted imaging (DWI), diffusion tensor imaging (DTI), and perfusion weighted imaging (PWI). Successfully perform difficult interventional techniques such as biopsies of the spine and interventional angiography-key techniques for more accurately diagnosing cerebral vascular disease, aneurysm, and blood vessel malformations-as well as percutaneous drainage and tumor ablation. Know what to expect. A dedicated section is organized by the clinical scenarios most likely to be encountered in daily practice, such as neurodegenerative disease, vascular disease, and cancer. Avoid common problems that can lead to an incorrect diagnosis. Tables and boxes with tips, pitfalls, and other teaching points show you what to look for, while problem-solving advice helps you accurately identify what you see-especially those images that could suggest several possible diagnoses. See conditions as they appear in practice thanks to an abundance of case examples and specially designed full-color, high-quality images which complement the text and highlight important elements.
  • Sect. I. Imaging technique -- sect. II. Anatomy -- sect. III. Devices -- sect. IV. Special situations -- sect. V. Disease entities by anatomic region.
  • Section 1. Headache -- Section 2. Head pain -- Section 3. Neck and shoulder -- Section 4. Upper limb -- Section 5. Thorax -- Section 6. Abdomen and pelvis -- Section 7. Spine -- Section 8. Hip and lower limb -- Section 9. Pain syndromes and special topics -- Index.
  • Problem-based physiology 2010, ClinicalKey
    Section 1. Nerves and muscles -- section 2. Cardiovascular physiology -- section 3. Renal water and electrolyte balance -- section 4. Hematology -- section 5. Respiration -- section 6. Neurology -- section 7. Gastroenterology -- section 8. Metabolism -- section 9. Endocrinology -- section 10. Reproduction.
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  • Procedia in vaccinology v. 1-, 2009-, ScienceDirect
  • This revised Sixth edition of "Procedures to Investigate Foodborne Illness" is designed to guide public health personnel or teams in any country that investigates reports of alleged foodborne illnesses. It is a companion to another manual published by the IAFP, "Procedures to Investigate Waterborne Illness". These two manuals are based on epidemiologic principles and investigative techniques that have been found effective in determining causal factors of disease incidence. This edition describes procedures to: Plan, prepare, investigate and respond to intentional contaminat.
  • Airway management and endotracheal intubation -- Central venous catheterization -- Arterial line placement and care -- Pulmonary artery catherization -- Temporary cardiac pacing -- Cardioversion and defibrillation -- Pericardiocentesis -- Chest tube insertion and care -- Bronchoscopy -- Thoracentesis -- Arterial puncture for blood gas analysis -- Tracheostomy -- Gastrointestinal endoscopy -- Paracentesis and diagnostic peritoneal lavage -- Gastroesophageal balloon tamponade for acute variceal hemorrhage -- Endoscopic placement of feeding tubes -- Cerebrospinal fluid aspiration -- Percutaneous suprapubic cystostomy -- Aspiration of the knee and synovial fluid analysis -- Anesthesia for bedside procedures -- Interventional radiology: drainage techniques -- Cardiopulmonary resuscitation -- Management of pain in the critically ill patient -- Therapeutic paralysis -- Dialysis therapy in the intensive care setting -- Therapeutic apheresis: technical considerations and indications in critical care -- Routine monitoring of critically ill patients -- Indirect calorimetry -- Minimally invasive cardiology -- Neurologic and intracranial pressure monitoring -- Echocardiography in the intensive care unit -- Monitoring gastrointestinal tract function -- Respiratory monitoring during mechanical ventilation.
  • Overview of the current process of new drug discovery and development / Charles G. Smith and James T. O'Donnell -- Integrated drug product development: from lead candidate selection to life-cycle management / Madhu Pudipeddi, Abu T.M. Serajuddin, and Daniel Mufson -- The impact of combinatorial chemistry on drug discovery / Michael H. Rabinowitz and Nigel Shankley -- High-throughput screening: enabling and influencing the process of drug discovery / Carol Ann Homon and Richard M. Nelson -- Pharmacological and pharmaceutical profiling: new trends / Joanne Bowes ... [et al.] -- Cell-based analysis of drug response using moving optical gradient fields / Jeff M. Hall ... [et al.]. -- Patient-derived primary cells in high-throughput differential antitumor screens: let the patients be the guide / Irwin A. Braude -- The evolving role of the caco-2 cell model to estimate intestinal absorption potential and elucidate transport mechanisms / Jibin Li and Ismael J. Hidalgo -- The promise of metabonomics in drug discovery / Harold J. Kwalwasser and Pauline Gee -- Pharmacogenetics and pharmacogenomics in drug development and regulatory decision-making: report of the first FDA-PWG-PhRMA-druSafe workshop / Lawrence J. Lesko ... [et al.] -- Drugs from molecular targets for CNS and neurodegenerative diseases / William T. Comer and Gönül Veliçelebi -- Safety pharmacology / Jean-Pierre Valentin and Tim G. Hammond -- Nonclinical drug safety assessment / Frederick E. Reno -- Preclinical genotoxicity testing: past, present and future / Richard H.C. San -- The need for animals in biomedical research / Charles G. Smith -- Defining the actual research approach to the new drug substance / Charles G. Smith -- Pharmacokinetics: pharmacodynamics in new drug development / Sarfaraz K. Niazi -- Pharmaceutics and compounding issues in new drug development and marketing / Loyd V. Allen -- Late stage and process development activities / Charles G. Smith -- Contract research organizations: role and function in new drug development / F. Richard Nichol -- The front lines of clinical research: the industry / Lori Nesbitt -- Horizons for cancer chemotherapy (and nonchemotherapy) / Daniel D. Von Hoff -- Human immunodeficiency virus/acquired immune deficiency syndrome: clinical testing challenges / Vincent Idemyor -- Common technical document: the changing face of the new drug application / Justina A. Molzon -- Electronic publishing / Heather L. Wallace -- The important role of pharmacists in a complex risk-management system: managing the risks from medical product use by focusing on patient education, monitoring, and adverse event reporting / Justina A. Molzon -- Liability, litigation, and lessons in new drug development / James T. O'Donnell -- Problems in the nondrug marketplace / Stephen Barrett -- Patents and new product development in the pharmaceutical and biotechnology industries / Henry Grabowski -- The pharmaceutical revolution: drug discovery and development / John C. Somberg -- The discovery of Rituxan / Mitchell E. Reff -- Funding the birth of a drug: lessons from the sell side / Howard E. Greene -- Innovations for the drug development pathway: what is needed now / Janet Woodcock -- Managing R & D uncertainty and maximizing the commercial potential of pharmaceutical compounds using the dynamic modeling framework / Mark Paich ... [et al.].
  • Harvest of a therapeutic protein product from high cell density fermentation broths : principles and case study / Elisabeth Russell, Alice Wang, and Anurag S. Rathore -- Expanded bed adsorption for capture from crude solution / Alan Sonnenfeld and Jorg Thommes -- Product recovery by high-gradient magnetic fishing / Matthias Franzreb ... [et al.] -- Protein refolding and scale up / Cynthia Cowgill, Asuman G. Ozturk, and Richard St. John -- Bulk protein crystallization, principles and methods / Mark R. Etzel -- Modes of preparative chromatography / Abhinav A. Shukla and Yinges Yigzaw -- Screening of chromatographic stationary phases / Abhinav A. Shukla and Xuejun Sean Han -- A priori prediction of chromatographic separations from protein structure data / Asif Ladiwala, Curt M. Breneman, and Steven M. Cramer -- Membrane chromatography : analysis of breakthrough curves and viral clearance / Mark R. Etzel and William T. Riordan -- Ultrafiltration process design and implementation / Herb Lutz and Bala Raghunath -- Virus filtration process design and implementation / Michael W. Phillips ... [et al.] -- Product recovery from transgenic sources / Chenming (Mike) Zhang and Kevin E. Van Cott -- Analytical strategy for biopharmaceutical development / Drew N. Kelner and Mahesh K. Bhalgat -- Evaluation of viral clearance in purification processes / Amitava Kundu and Karl Reindel -- Advances in viral clearance / Kurt Brorson -- Protein A affinity chromatography for capture and purification of monoclonal antibodies and Fc-fusion proteins: practical considerations for process development / Sanchayita Ghose, Thomas McNerney, and Brian Hubbard -- Polishing methods for monoclonal IgG purification / Pete Gagnon -- Making changes to a biopharmaceutical manufacturing process during development and commercial manufacturing : the REMICADE story / Peter W. Wojciechowski ... [et al.] -- Linear scale-up of ultrafiltration of high viscosity process streams / Christopher Daniels ... [et al.] -- A membrane chromatography application : a rapid, high capacity gene therapy vector purification tool / Ajay R. Lajmi, Robert Kutner, and Jakob Reiser.
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    In the beginning -- Evolution -- A little bit of chemistry -- The structure and function of bacteria -- Biological macromolecules -- Eukaryotes -- Multicellular organisms and development -- Anatomy, physiology, and systems biology -- Disease and its treatment -- Molecular biotechnology -- Molecular bioethics.
  • Signs and symptoms -- Selected signs and symptoms -- Potential agents of bioterrorism -- Common signs and symptoms associated with herbs -- Obtaining a health history -- Guide to laboratory test results.
  • Signs & symptoms (A-Z) -- Appendices -- Selected signs & symptoms -- Potential agents of bioterrorism -- Adverse effects associated with herbs -- Obtaining a health history -- Guide to laboratory test results.
  • At the center of this book is the complex and perplexing question of how to design professional preparation programs, organizational management practices, public policy systems and robust professional associations committed to and capable of, maintaining confidence, trust and the other hallmarks of responsible professionalism. To do this, we need to rebuild our understanding of professional responsibility from the ground up. We describe how individuals might be prepared to engage in responsible professional service delivery, examine promising options for the reform of professional service systems and finally, outline a reform strategy for improving practice in education and medicine ? two essential public services. The nexus of the reform problem in professionalism is establishing a more robust and effective working relationship between teachers and their students; between health care professionals and their patients and between educators and health professionals. Professionalism means acceptance of professional responsibility for student and patient outcomes ? not just acceptance of responsibility for technical expertise, but commitment to the social norms of the profession, including trustworthiness and responsibility for client wellbeing. In the past, it may have been sufficient to assume that adequate knowledge can be shaped into standards of professional practice. Today, it is clear that we must take careful account of the ways in which practicing professionals develop, internalize and sustain professionalism during their training, along with the ways in which this commitment to professionalism may be undermined by the regulatory, fiscal, technological, political and emotional incentive systems that impinge on professional workplaces and professional employment systems.
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    Part I. Theology of spritual/pastoral care : -- 1. Creating a personal theology to do spiritual/pastoral care -- 2. Creating a personal theology to do spiritual/pastoral care -- Part II. The process of spiritual/pastoral care : -- 3. The process of spiritual/pastoral care: a general theory for providing spiritual/pastoral care using palliative care as a paradigm -- 4. Assessments -- 5. Creating and implementing a spiritual/pastoral care plan -- 6. Chaplains and charting -- 7. Foundational listening and responding skills -- 8. Prayer and ritual -- 9. Counseling and interventions -- 10. Inspiring hope: confronting fear, guilt and shame in spiritual/pastoral care -- 11. Life review -- 12. End-of-life chaplaincy care -- 13. Ethics and the care of the sick: an overview for professional chaplains and other spiritual/pastoral care providers -- 14. Spirituality groups -- 15. Spiritual care of staff -- 16. Gender issues in pastoral care -- 17. Working with community religious resources -- 18. Transdisciplinary relationships -- Part III. Spiritual/pastoral care with special populations : -- 19. Spiritual/pastoral care in worlds beyond: ministry to international and immigrant patients -- 20. Pediatric chaplancy -- 21. Behavioral health -- 22. Gay, lesbian, bisexual, and transgendered (GLBT) people -- 23. Spritual/pastoral care with people with disabilities and their families -- 24. Chronic illness -- 25. Complicated grief: exploring arresting grief and survival grief in spiritual/pastoral care -- Part IV. The infrastructure of spiritual/pastoral care : -- 26. Strategic planning: a basis for all infrastructure development and growth within spiritual/pastoral care -- 27. Outcome oriented chaplaincy: itentional caring -- 28. Referral plans: developing and implementing tactical plans regarding who chaplains should visit -- 29. Quality improvement: A chaplaincy priority -- 30. Health care chaplaincy as a research-informed profession -- 31. Cultural Competencies -- 32. Sacred space -- 33. Blessings of a mixed population: institutional prayer in multifaith communities
  • Professionalism and Ethics in Medicine: A Study Guide for Physicians and Physicians-in-Training is a unique self-study guide for practitioners and trainees covering the core competency areas of professionalism, ethics, and cultural sensitivity. This novel title presents real-world dilemmas encountered across the specialties of medicine, offering guidance and relevant information to assist physicians, residents, and medical students in their decision-making. The text is divided into two parts: Foundations and Questions with Answers. The first part provides a substantive foundation of knowledge in the principles, scholarship, policy guidelines, and decision-making strategies of the modern health professions. The second part assists practitioners and trainees in preparing for the complex issues that arise each day in the settings where health professionals work and train ? clinics, research centers, educational contexts, and communities. Developed by renowned leaders in a broad range of clinical fields, Professionalism and Ethics in Medicine: A Study Guide for Physicians and Physicians-in-Training is a major, invaluable contribution to the literature and an indispensable reference for clinicians at all levels.
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  • Programmed cell death ScienceDirect
    Fulltext (v. 6) ScienceDirect
    v. 1. Cellular and molecular mechanisms -- v. 2. Role in disease, pathogenesis, and prevention.
  • Cell death : history and future / Zahra Zakeri and Richard A. Lockshin -- Caspase mechanisms / Guy S. Salvesen and Stefan J. Riedl -- The mitochondrial death pathway / Anas Chalah and Roya Khosravi-Far -- Apoptotic pathways in tumor progression and therapy / Armelle Melet ... [et al.] -- Therapeutic targeting of death pathways in cancer : mechanisms for activating cell death in cancer cells / Ting-Ting Tan and Eileen White -- Overcoming resistance to apoptosis in cnacer therapy / Peter Hersey, Xu Dong Zhang, and Nizar Mhaidat -- Trail receptors : targets for cancer therapy / Robin C. Humphreys and Wendy Halpern -- Rational design of therapeutics targeting the BCL-2 family : are some cancer cells primed for death but waiting for a final push? / Victoria Del Gaizo Moore and Anthony Letai -- Autophagy and tumor suppression : recent advancesin understanding the link between autophagic cell death pathways and tumor development / Shani Bialik and Adi Kimchi -- Regulation of programmed cell death by the P53 pathway / Kageaki Kuribayashi and Wafik S. El-Deiry -- Regulation of programmed cell death by NF-[kappa]B and its role in tumorigenesis and therapy / Yongjun Fan ... [et al.] -- Targeting proteasomes as therapy in multiple myeloma / Dharminer Chauhan, Teru Hideshima, and Kenneth C. Anderson -- Histone deacetylase inhibitors : mechanisms and clinical significance in cancer : HDAC inhibitor-induced apoptosis / Sharmila Shankar and Rakesh K. Srivastava -- RNA interference and cancer : endogenous pathways and therapeutic approaches / Derek M. Dykxhoorn, Dipanjan Chowdhury, and Judy Lieberman -- Cancer stem cells and impaired apoptosis / Zainab Jagani and Roya Khosravi-Far.
  • The recent advances in Programming Somatic Cell (PSC) including induced Pluripotent Stem Cells (iPS) and Induced Neuronal phenotypes (iN), has changed the experimental landscape and opened new possibilities. The advances in PSC have provided an important tool for the study of human neuronal function as well as neurodegenerative and neurodevelopmental diseases in live human neurons in a controlled environment. For example, reprogramming cells from patients with neurological diseases allows the study of molecular pathways particular to specific subtypes of neurons such as dopaminergic neurons in Parkinson.s Disease, Motor neurons for Amyolateral Sclerosis or myelin for Multiple Sclerosis. In addition, because PSC technology allows for the study of human neurons during development, disease-specific pathways can be investigated prior to and during disease onset. Detecting disease-specific molecular signatures in live human brain cells, opens possibilities for early intervention therapies and new diagnostic tools. Importantly, it is now feasible to obtain gene expression profiles from neurons that capture the genetic uniqueness of each patient. Importantly, once the neurological neural phenotype is detected in vitro, the so-called "disease-in-a-dish" approach allows for the screening of drugs that can ameliorate the disease-specific phenotype. New therapeutic drugs could either act on generalized pathways in all patients or be patient-specific and used in a personalized medicine approach. However, there are a number of pressing issues that need to be addressed and resolved before PSC technology can be extensively used for clinically relevant modeling of neurological diseases.
  • Programming .NET 3.5 SU Catalog (SearchWorks)
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  • "Preface About this book Two common types of user interfaces in statistical computing are the command line interface (CLI) and the graphical user interface (GUI). The usual CLI consists of a textual console in which the user types a sequence of commands at a prompt, and the output of the commands is printed to the console as text. The R console is an example of a CLI. A GUI is the primary means of interacting with desktop environments, such as Windows and Mac OS X, and statistical software, such as JMP. GUIs are contained within windows, and resources, such as documents, are represented by graphical icons. User controls are packed into hierarchical drop-down menus, buttons, sliders, etc. The user manipulates the windows, icons, and menus with a pointer device, such as a mouse. The R language, like its predecessor S, is designed for interactive use through a command line interface (CLI), and the CLI remains the primary interface to R. However, the graphical user interface (GUI) has emerged as an effective alternative, depending on the specific task and the target audience. With respect to GUIs, we see R users falling into three main target audiences: those who are familiar with programming R, those who are still learning how to program, and those who have no interest in programming. On some platforms, such as Windows and Mac OS X, R has graphical front-ends that provide a CLI through a text console control. Similar examples include the multi-platform RStudioTM IDE, the Java-based JGR and the RKWard GUI for the Linux KDE desktop. Although these interfaces are GUIs, they are still very much in essence CLIs, in that the primary mode of interacting with R is the same. Thus, these GUIs appeal mostly to those who are comfortable with R programming"-- Provided by publisher.
  • Programming Visual Basic 2008. 1st ed. SU Catalog (SearchWorks)
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  • Progress in brain research v. 1-, 1963-, ScienceDirect
  • Progress in drug research v. 62-, 2005-, Springer
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  • This volume is a reference handbook focusing on diseases like Marfan syndrome, Ehlers-Danlos syndrome, Loeys-Dietz syndrome and other heritable soft connective tissue diseases. The book presents detailed information for both basic scientists and for clinicians seeing patients. It is also a stepping stone for new investigations and studies that goes beyond the facts about the composition and biochemistry of the connective tissue and extracellular matrix, as the authors connect individual components to specific aspects of various soft tissue disorders and to the actual or potential treatment of them. Progress in Heritable Soft Connective Tissue Diseases features very prominent physicians and scientists as contributors who bring their most recent discoveries to the benefit of readers. Their expertise will help clinicians with proper diagnosis of sometimes elusive and uncommon heritable diseases of soft connective tissues. This book also offers an update on the pathophysiology of these diseases, including an emphasis on unifying aspects such as connections between embryonic development of the different types of connective tissues and systems, and the role of TGF-beta in development and physiology of soft tissues. This new set of data explains, at least in part, why many of these disorders are interconnected, though the primary pathophysiological events, such as gene mutations, may be different for each disorder.
  • IX Professor Kazuyuki Sasaki, MD: clinician, scientist, leader in cataract research and friend -- 1 Lens and cataract research of the 20th century: a review of results, errors and misunderstandings -- 12 Rick factors for nuclear lens opacification: the Reykjavik eye study -- 21 A review of the epidemiologic evidence linking ultraviolet radiation and cataracts -- 32 Studies on ultraviolet radiation and health effects: ocular exposure to ultraviolet radiation -- 40 Geometrical gradients in the distribution of temperature and absorbed ultraviolet radiation in ocular tissues -- 60 High prevalence of nuclear cataract in the population of tropical and subtropical areas -- 70 Toxicity of ultraviolet radiation exposure to the lens expressed by maximum tolerable dose -- 76 Assessment of ocular exposure to visible light for population studies -- 93 The effects of protective eyewear on glare and crystalline lens transparency -- 104 Evaluation of blue-light hazards form various light sources -- 113 Experimental evidence for interactive effects of chronic UV irradiation and nutritional deficiencies in the lens -- 125 Environmental temperature and cataract progression in experimental rat cataract models -- 135 Morphological differences between lens fibers in albino and pigmented rats -- 143 Heterogeneity of ascorbate free radical reductase in the human lens -- 150 The effect of modification of [alpha]-crystallin by prednisolone -21-hemisuccinate and fructose 6-phosphate on chaperone activity -- 161 Steroid-induced cataract: other than in the who animal system, in the lens culture system, androgens, estrogens and progestins as well as glucocorticoids produce a loss o transparency of the lens -- 169 Water diffusion in the rabbit lens in vivo -- 176 Author index -- 177 Subject index.
  • "This volume is the most recent installment of the Progress in Motor Control series. It contains contributions based on presentations by invited speakers at the Progress in Motor Control IX meeting held in at McGill University, Montreal, in July, 2013. Progress in Motor Control is the official scientific meeting of the International Society of Motor Control (ISMC). The Progress in Motor Control IXI meeting, and consequently this volume, provide a broad perspective on the latest research on motor control in humans and other species"--Publisher's description.
  • Model-based and model-free mechanisms of human motor learning / Adrian M. Haith, John W. Krakauer -- The molecular basis of experience-dependent motor system development / Robert G. Kalb, Weiguo Zhou, Lei Zhang -- Neurocognitive mechanisms of error-based motor learning / Rachael D. Seidler ... [et al.] -- Plasticity in the motor network following primary motor cortex lesion / Numa Dancause -- The mirror system in monkeys and humans and its possible motor-based functions / Leonardo Fogassi, Luciano Simone -- A molecular basis for intrinsic muscle properties : implications for motor control / Kiisa C. Nishikawa ... [et al.] -- Theoretical and methodological issues in serial correlation analysis / Didier Delignières, Vivien Marmelat -- On the control of unstable objects : the dynamics of human stick balancing / Ramesh Balasubramaniam -- Intermittent motor control : the "drift-and-act" hypothesis / John G. Milton.
  • Progress in parasitology 2011, Springer
    50 years German Society of Parasitology (DGP) (1961-2010) / Johannes Eckert -- Parasitology of the German Democratic Republic (1961-1990) : memories of a time witness / Theodor Hiepe -- Parasites and their world records in their fight for survival / Heinz Mehlhorn -- Cryptosporidium parvum : the veterinary perspective / Arwid Daugschies -- Neonatal porcine coccidiosis / Hanna Lucia Worliczek and Anja Joachim -- Post-translational modifications in apicomplexan parasites / Esther Jortzik, Sebastian Kehr, and Katja Becker -- Development of the RTS, S/AS vaccine candidate from concept to phase III / Joe Cohen ... [et al.] -- Small ruminant theileriosis / Jabbar Ahmed ... [et al.] -- Interactions of Trypanosoma cruzi and triatomines / Günter A. Schaub, Christian K. Meiser, and Carsten Balczun -- Sex in schistosomes -- signaling mechanisms in the female gonads / Svenja Beckmann ... [et al.] -- Anisakid nematode (Ascaridoidea) life cycles and distribution : increasing zoonotic potential in the time of climate change? / Sven Klimpel and Harry W. Palm -- Fish parasites as biological indicators in a changing world : can we monitor environmental impact and climate change? / Harry W. Palm -- Infectious diseases under the influence of changing environmental factors / Franz J. Conraths and Thomas C. Mettenleiter -- Arthropod vectors and their growing importance in Europe / Helge Kampen and Doreen Werner -- A look at the world of ticks / Trevor N. Petney ... [et al.] -- What else besides TBE and borreliosis? : tick-transmitted pathogens in Germany and beyond / Silvia Pluta ... [et al.] -- Tick-borne encephalitis : from microfocus to human disease / G. Dobler ... [et al.].
  • pt. 1. Social Psychiatry and Psychiatric Epidemiology -- Definition and Historical Review of Social Psychiatry and Psychiatric Epidemiology -- The Foundation of Psychiatric Epidemiology Research -- Introduction -- pt. 2. Findings on Social Psychiatry and Psychiatric Epidemiology in Japan -- Activities of the Department of Neuropsychiatry Nagasaki University School of Medicine, as a World Health Organization Collaborating Center -- Studies on Schizophrenia -- Studies on Affective Disorders -- Studies on Patient with Affective Disorders in General Practice -- Development from Atomic Bomb Diseases to Survivors' Mental Health Support: Findings on Disaster Psychiatry.
  • Progress in tumor research v. 41-, 2014-, Karger
  • "Even though progress towards the MDG target represents important gains in access for billions of people around the world, it has been uneven. Sharp geographic, sociocultural and economic inequalities in access persist and sometimes have increased. This report presents examples of unequal progress among marginalized and vulnerable groups. Section 1 presents the status of and trends in access to improved drinking water sources and sanitation. Section 2 provides a snapshot of inequalities in access to improved drinking water sources and sanitation. Section 3 presents efforts to strengthen monitoring of access to safe drinking water and sanitation services under a post-2015 development agenda, as well as the challenges associated with these efforts."--Publisher's website.
  • Progressive multiple sclerosis places a huge burden on individuals, carers and society and treatment options are currently limited. However, there have been significant recent advances in understanding progressive disease and this book draws the field together into a single, accessible, clinically focused text. Progressive Multiple Sclerosis sets out the basic science, pathology, epidemiology and treatment possibilities in progressive multiple sclerosis. The biological processes underlying disease progression are elucidated as are specific pathophysiological mechanisms. The basic science of axonal degeneration and the clinical understanding of progressive multiple sclerosis are discussed in the context of emerging and future therapies for disease progression as are trials which might be conducted for progressive multiple sclerosis. An overview of biomarkers for the disease is included and existing symptomatic therapies for progressive multiple sclerosis are covered in detail. Each chapter addresses specific aspects of progressive multiple sclerosis providing an extensive review of the current literature and a discussion of the likely mechanisms of tissue injury relevant to the disease. Progressive Multiple Sclerosis is ideal for both general neurologists and those with a specialist interest in multiple sclerosis. It will also be of interest to neurologists in training and other medical professionals treating this common disease. Dr Alastair Wilkins is Senior Lecturer in Neurology, University of Bristol, and Consultant Neurologist at Frenchay Hospital, Bristol, UK. He researches axonal injury in multiple sclerosis and related disorders.
  • "A growing number of healthcare organizations are implementing project management principles to improve cost and service efficiencies. They are in desperate need of resources that clearly illustrate the project management needs of todays healthcare professional. Project Management for Healthcare fills this need. Using easy-to-follow language, it explains how the time-tested principles of project management can help maximize limited resources and ensure the highest possible quality of care. Exploring the discipline of project management from the perspective of the healthcare environment, the book dissects the project process and provides the tools and techniques required to successfully plan, execute, and control any healthcare-based project. From identifying stakeholders to constructing a project plan, this book covers the complete spectrum of project planning activities. Complete with chapter summaries, exercises, hints, review questions, and case studies, it illustrates applications across a range of healthcare settings. Explains how to utilize the project plan to execute projects within budget, schedule, and quality objectives Covers program management as it relates to healthcare Addresses the interaction between healthcare and information technology Presents best practices from the pharmaceutical and medical equipment industries that can easily be adapted to any helthcare setting Because most healthcare personnel will inevitably have to work with program management and need to interact with pharmaceutical companies and medical device manufacturers, the book provides an inside look at the processes and best practices used to bring products to market in these industries. Explaining how to adapt these processes to drive down costs and improve the quality of care in any healthcare setting, the book includes a case study of a fictitious medical facility that illustrates the proper application of the tools and techniques needed to manage healthcare projects effectively and efficiently"--Provided by publisher.
  • The gut microbiota -- Prebiotics -- Probiotics -- Identification of pathogens by classical clinical tests -- Identification of pathogens by nonculturing molecular techniques -- Bacterial adhesion -- Cholera -- Tuberculosis -- Legionnaires' disease -- Listeria -- Diphtheria -- Botulism and tetanus -- Whooping cough -- Dysentery -- Urinary tract infections -- Burn infections -- Typhoid -- Meningitis -- Rickettsiia diseases -- Syphilis -- Chlamydial diseases -- Bacterial toxins.
  • Organic Acid and Solvent Production: Acetic, Lactic, Gluconic, Succinic, and Polyhydroxyalkanoic Acids / Palmer Rogers, Jiann-Shin Chen, Mary Jo Zidwick -- Organic Acid and Solvent Production: Butanol, Acetone, and Isopropanol; 1,3- and 1,2-Propanediol Production; and 2,3-Butanediol Production / Jiann-Shin Chen, Mary Jo Zidwick, Palmer Rogers -- Organic Acid and Solvent Production: Propionic and Butyric Acids and Ethanol / Mary Jo Zidwick, Jiann-Shin Chen, Palmer Rogers -- Amino Acid Production / Hidehiko Kumagai -- Microbial Exopolysaccharides / Avinash Mishra, Dr. Bhavanath Jha -- Bacterial Enzymes / Prof. Wim J. Quax -- Diversity and Biotechnological Applications of Prokaryotic Enzymes / Alane Beatriz Vermelho, Eliane Ferreira Noronha, Edivaldo Ximenes Ferreira Filho -- Bacteria in Food and Beverage Production / Dr. Michael P. Doyle, Larry R. Steenson, Jianghong Meng -- Bacterial Pharmaceutical Products / Giancarlo Lancini, Dr. Arnold L. Demain -- Biosurfactants / Dr. Eugene Rosenberg, Eliora Z. Ron -- Bioremediation / Ronald L. Crawford, Dr. Eugene Rosenberg -- Biodeterioration / Ji-Dong Gu, Ralph Mitchell -- Microbial Biofilms / Dirk De Beer, Paul Stoodley -- Biofuels / Stefano Freguia, Bernardino Virdis, Dr. Korneel Rabaey -- The Metabolic Pathways of Biodegradation / Lawrence P. Wackett.
  • Section 1: Biology of Bacteria and Archaea. How We Do, Don't, and Should Look at Bacteria and Bacteriology / Carl R. Woese -- What Is a Prokaryote? / W. Ford Doolittle, Olga Zhaxybayeva -- Prokaryotes and Their Habitats / Hans G. Schlegel, Holger W. Jannasch -- Origin of Life: RNA World Versus Autocatalytic Anabolist / Günter Wächtershäuser -- Morphological and Physiological Diversity / Stephen H. Zinder, Martin Dworkin -- Prokaryote Characterization and Identification / Peter Kämpfer, Stefanie P. Glaeser -- Principles of Enrichment, Isolation, Cultivation, and Preservation of Prokaryotes / Jörg Overmann -- Comparative Genomics / Asli Ismihan Ozen, Tammi Vesth, David W. Ussery -- Defining Taxonomic Ranks / Konstantinos T. Konstantinidis, Erko Stackebrandt -- Population Genetics / Santiago Castillo-Ramírez, Edward J. Feil -- Public Service Collections and Biological Resource Centers of Microorganisms / David Smith, Dagmar Fritze, Erko Stackebrandt -- Repositories for Patented and Safeguarded Material / Zea D. V. L. Mayerhoff, Irene von der Weid, Alessandra B. G. Valladão -- Biotechnology and Applied Microbiology / Eugene Rosenberg -- Genomes and Post-genome Technology / Betania Ferraz Quirino, Cristine Chaves Barreto, Georgios J. Pappas Jr. -- Section 2: Symbiotic Associations. Role of Microorganisms in Adaptation, Development, and Evolution of Animals and Plants: The Hologenome Concept / Eugene Rosenberg, Ilana Zilber-Rosenberg -- Cyanobacterial-Plant Symbioses / David G. Adams, Birgitta Bergman, Sandra A. Nierzwicki-Bauer, Paula S. Duggan -- Root and Stem Nodule Bacteria of Legumes / Michael J. Sadowsky, Peter H. Graham, Masayuki Sugawara -- Symbiotic Associations Between Ciliates and Prokaryotes / Michael Schweikert, Masahiro Fujishima, Hans-Dieter Görtz -- Bacteriocyte-Associated Endosymbionts of Insects / Paul Baumann, Nancy A. Moran, Linda C. Baumann -- Vibrio fisheri: Squid Symbiosis / Eric V. Stabb, Karen L. Visick -- Rumen Symbioses / Itzhak Mizrahi -- Symbiotic Associations Between Termites and Prokaryotes / Andreas Brune -- Marine Chemosynthetic Symbioses / Colleen M. Cavanaugh, Zoe P. McKiness, Irene L. G. Newton, Frank J. Stewart.
  • Section 1: Prokaryotic Communities. Structure and Function of Microbial Communities / David A. Stahl, Jason J. Flowers, Meredith Hullar, Seana Davidson -- Quantitative and Theoretical Microbial Population Biology / Martin F. Polz, William P. Hanage -- Alpine and Arctic Soil Microbial Communities / M. Rhodes, J. Knelman, R. C. Lynch, J. L. Darcy, D. R. Nemergut, S. K. Schmidt -- Plant Rhizosphere Microbial Communities / Dror Minz, Maya Ofek, Yitzhak Hadar -- Tropical Soil Microbial Communities / Andrew Macrae, Rosalie R. R. Coelho, Raquel Peixoto, Alexandre S. Rosado -- Freshwater Microbial Communities / Jakob Pernthaler -- Pelagic Oxygen Minimum Zone Microbial Communities / Osvaldo Ulloa, Jody J. Wright, Lucy Belmar, Steven J. Hallam -- Marine Deep Sediment Microbial Communities / Andreas Teske -- Sea-Ice Microbial Communities / John P. Bowman -- Coral Reef Bacterial Communities / David G. Bourne, Nicole S. Webster -- Section 2: Ecophysiology -- Planktonic Versus Sessile Life of Prokaryotes / Kevin C. Marshall -- The Phototrophic Way of Life / Jörg Overmann, Ferran Garcia-Pichel -- The Anaerobic Way of Life / Ruth A. Schmitz, Rolf Daniel, Uwe Deppenmeier, Gerhard Gottschalk -- The Chemolithotrophic Prokaryotes / Donovan P. Kelly, Ann P. Wood -- Bacterial Behavior / Judith P. Armitage, Kathryn A. Scott -- Prokaryotic Life Cycles / Lawrence J. Shimkets -- Life at High Temperatures / Rainer Jaenicke, Reinhard Sterner -- Life at Low Temperatures / Thilo M. Fuchs, Klaus Neuhaus, Siegfried Scherer -- Life at High Salt Concentrations / Aharon Oren -- Alkaliphilic Prokaryotes / Terry Ann Krulwich, Masahiro Ito -- Syntrophism Among Prokaryotes / Bernhard Schink, Alfons J. M. Stams -- Quorum Sensing / Bonnie L. Bassler, Melissa B. Miller -- Cell-Cell Interactions / Dale Kaiser.
  • Physiology and Biochemistry -- Acetogenic Prokaryotes / Harold L. Drake, Kirsten Küsel, Carola Matthies -- Virulence Strategies of Plant Pathogenic Bacteria / Maeli Melotto, Barbara N. Kunkel -- Oxidation of Inorganic Nitrogen Compounds as an Energy Source / Eberhard Bock, Michael Wagner -- H₂-Metabolizing Prokaryotes / Edward Schwartz, Johannes Fritsch, Bärbel Friedrich -- Hydrocarbon-Oxidizing Bacteria / Eugene Rosenberg -- Lignocellulose-Decomposing Bacteria and Their Enzyme Systems / Edward A. Bayer, Yuval Shoham, Raphael Lamed -- Aerobic Methylotrophic Prokaryotes / Ludmila Chistoserdova, Mary E. Lidstrom -- Dissimilatory Fe(III)- and Mn(IV)-Reducing Prokaryotes / Derek Lovley -- Dissimilatory Sulfate- and Sulfur-Reducing Prokaryotes / Ralf Rabus, Theo A. Hansen, Friedrich Widdel -- Denitrifying Prokaryotes / James P. Shapleigh -- Dinitrogen-Fixing Prokaryotes / Ernesto Ormeño-Orrillo, Mariangela Hungria, Esperanza Martinez-Romero -- Magnetotactic Bacteria / Dennis A. Bazylinski, Christopher T. Lefèvre, Dirk Schüler -- Luminous Bacteria / Paul V. Dunlap, Henryk Urbanczyk -- Halophilic and Haloalkaliphilic Sulfur-Oxidizing Bacteria / Dimitry Y. Sorokin, Horia Banciu, Lesley A. Robertson, J. Gijs Kuenen -- Colorless Sulfur Bacteria / Gerard Muyzer, J. Gijs Kuenen, Lesley A. Robertson -- Bacterial Stress Response / Eliora Z. Ron -- Anaerobic Biodegradation of Hydrocarbons Including Methane / Johann Heider, Karola Schühle -- Physiology and Biochemistry of the Methane-Producing Archaea / Reiner Hedderich, William B. Whitman.
  • Part I. Cell Wall Polymers and Structures of Bacteria -- 1. The Murein Sacculus / Silke Litzinger and Christoph Mayer -- 2. Occurrence, Structure, Chemistry, Genetics, Morphogenesis, and Functions of S-Layers / Paul Messner, Christina Schäffer, Eva-Maria Egelseer, and Uwe B. Sleytr -- 3. Bacterial Polysaccharide Capsules / David Corbett, Thomas Hudson, and Ian S. Roberts -- 4. Lipopolysaccharides / Alba Silipo, Cristina De Castro, Rosa Lanzetta, Michelangelo Parrilli, and Antonio Molinaro -- 5. Structure, Biosynthesis, and Function of Teichoic Acids and Related Cell Wall Glycopolymers in the Gram-positive Cell Envelope / Maren Rautenberg, Thomas Kohler, Guoqing Xia, Emir Kulauzovic, and Andreas Peschel -- 6. Outer Membrane Proteins / Oliver Mirus, Alexander Hahn, and Enrico Schleiff -- Part II. Cell Wall Polymers and Structures of Archaea -- 7. Cell Envelopes of Methanogens / Harald Claus and Helmut König -- 8. The Cell Envelopes of Haloarchaea: Staying in Shape in a World of Salt / Jerry Eichler, Mehtap Abu-Qarn, Zvia Konrad, Hilla Magidovich, Noa Plavner, and Sophie Yurist-Doutsch -- 9. Cell Envelopes of Crenarchaeota and Nanoarchaeota / Reinhard Rachel -- Part III. Biological Activities -- 10. Immunochemistry of the Cell Walls of Methanogenic Archaea: A View from the Past into the Future / Everly Conway de Macario and Alberto J.L. Macario -- 11. Cell Wall Structure and Pathogenicity / T.A. Oelschlaeger, U. Dobrindt, and J. Hacker -- Part IV. Cell Wall Growth and Inhibition -- 12. Cell Wall Targeted Antibiotics / Regine Hakenbeck, Reinhold Brückner, and Bernhard Henrich -- 13. Bacterial Autolysins / Marie-Pierre Chapot-Chartier -- Part V. Cell Wall Interactions -- 14. Prokaryotic Cell-Cell Interaction / Reinhard Wirth -- 15. Adhesion of Bacteria to Protists / Renate Radek -- Part VI. Application of Cell Wall Components -- 16. Prokaryotic Cell Wall Components: Structure and Biochemistry / Uwe B. Sleytr, Eva-Maria Egelseer, Nicola Ilk, Paul Messner, Christina Schäffer, Dietmar Pum, and Bernhard Schuster -- 17. Accumulation of Heavy Metals by Micro-organisms: Biomineralization and Nanocluster Formation / Sonja Selenska-Pobell and Mohamed Merroun.
  • Introduction -- Type I Toxin - Antitoxin Systems: Hok/Sok and Fst -- Novel Type I Toxin - Antitoxin Systems -- Type II TA Loci: The Ccdab and Parde Families -- Type II TA Loci: The Relbe Family -- Type II TA Loci: The Unusual Mqsra Locus -- Type II TA Loci: The Mazef Family -- Type II TA Loci: Vapbc and Other TA Loci In Mycobacteria -- Type II TA Loci: Phd Doc Family -- Type II TA Loci: The Fic Family -- Type II TA Loci, Hipab And Persisters -- Type II TA Loci: Zeta/Pezt Family -- Type II Loci: Phylogeny -- Type III TA Loci -- TA Loci Encoded By Plasmids -- TA Loci in Archaea -- TA Loci in Mycobacterium Tuberculosis -- TA Loci in Streptococcus Pneumoniae -- Biotechnological and Medical Exploitations Of TA Genes and Their Components.
  • Melanocyte system for studying stem cell niche -- Establishment and maniupulation of monkey and human embryonic stem cell lines for biomedical research -- Human embryonic stem cell derivation -- In search of the elusive epidermal stem cell -- Corneal cells for regeneration -- Polycomb gene product Bmi-l -- Directed differentiation of neural and sensory tissues from embryonic stem cells in vitro -- Stem cell biology for vascular regeneration.
  • ch. 1. Introduction / David L. Hull and Marc H. V. Van Regenmortel, p. 1-13 -- ch. 2. Emergent Properties of Biological Molecules and Cells / Robert J. P. Williams, p. 15-34 -- ch. 3. From Nineteenth Century Ideas on Reduction in Physiology to Non-Reductive Explanations in Twentieth-Century Biochemistry / Claude Debru, p. 35-46 -- ch. 4. Pitfalls of Reductionism in Immunology / Marc H. V. Van Regenmortel, p. 47-66 -- ch. 5. Reductionism in Medicine: Social Aspects of Health / Elisabeth A. Lloyd, p. 67-82 -- ch. 6. 'Who's Afraid of Reductionism?' 'I Am!' / Stanley Shostak, p. 83-111 -- Round Table Discussion 1/ chair Alex Rosenberg, p. 113-123 -- ch. 7. Reductionism in an Historical Science / Alex Rosenberg, p. 125-160 -- ch. 8. Varieties of Reductionism: Derivation and Gene Selection / David L. Hull, p. 161-177 -- ch. 9. The Gene: Between Holism and Generalism / Michel Morange, p. 179-189 -- ch. 10. Genes versus Molecules: How To, and How Not To, Be a Reductionist / Sahotra Sarkar, p. 191-209 -- ch. 11. Limits of Reproduction: A Reductionistic Research Strategy in Evolutionary Biology / James Griesemer, p. 211-231 -- ch. 12. Evolutionary Psychology: A Case Study in the Poverty of Genetic Determinism / John Dupré, p. 233-251 -- Round Table Discussion 2 / chair Marc Van Regenmortel, p. 253-260 -- ch. 13. The Ethical Imperative of Holism in Medicine / Alfred I. Tauber, p. 261-278 -- ch. 14. Levels of Explanation in Human Behaviour: The Poverty of Evolutionary Psychology / Steven P. R. Rose, p. 279-304 -- ch. 15. Reductionism and Social Policy / Dorothy Nelkin, p. 305-321 -- ch. 16. Reductionism, Complexity and Molecular Medicine: Genetic Chips and the 'Globalization' of the Genome / Kenneth F. Schaffner, p. 323-351 -- Round Table Discussion 3 / chair Kenneth F. Schaffner, p. 353-363.
  • Pt. 1. General principles and concepts. Introduction to health promotion for working women: a methodology / Pania Karnaki ... [et al.] -- The legal context for workplace safety and health promotion: thinking of women / Ioannis Polychronakis ... [et al.] -- Pt. 2. Specific health topics. Workplace health promotion interventions concerning women workers' occupational hazards / Ioannis Polychronakis ... [et al.] -- Mental health disorders and work-life balance / Natalie M. Schmitt, Andreas Fuchs and Wilhelm Kirch -- Musculoskeletal disorders / Verka Koytcheva ... [et al.] -- Work-related violence, bullying, and sexual harassment / Kaisa Kauppinen and Tarita Tuomola -- Promoting health for working women: communicable diseases / Sotirios Tsiodras -- Screening at the workplace and female employees / Elena Riza and Athena Linos -- Pt. 3. Women's reproductive health issues. Workplace health promotion aiming at safe working environments for pregnant women / Alex Burdorf and Goedele Geuskens -- Workplace health promotion aimed at increasing breastfeeding / Goedele Geuskens and Alex Burdorf -- Pt. 4. Lifestyle determinants. Promoting tobacco awareness and smoking cessation for working women / Sherry Merkur -- Women, health, and alcohol-related harm / Kaisa Kauppinen and Tarita Tuomola -- Promoting physical activity and a healthy diet among working women / Gemma Janer and Manolis Kogevinas.
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  • The phenomenon of self-change: overview and key issues -- Self-change from alcohol and drug abuse: often-cited classics -- Natural recovery or recovery without treatment from alcohol and drug problems as seen from survey data -- Remission without formal help: new directions in studies using survey data -- Natural recovery from alcohol and drug problems: a methodological review of the literature from 1999 through 2005 -- Self-change in a broader context: beyond alcohol and drugs -- One way to leave your lover: the role of treatment in changing addictive behaviors -- Promoting self-change: taking the treatment to the community -- Hostile and favorable societal climates for self-change: some lessons for policymakers -- Natural recovery: a cross-cultural perspective -- Self-change toolbox: tools, tips, websites, and other informational resources for assessing and promoting self-change.
  • Virology and pathogenesis / Pfister, H. -- Epidemiology of mucosotropic papillomaviruses / Gissmann, L. -- Condylomata acuminata / Gross, G. -- Recurrent respiratory papillomatosis / Wittekindt, C.; Wagner, S.; Klussmann, J.P. -- Cervical cancer and intraepithelial neoplasia / Schneider, A. ... [et al.] -- Cancer and intraepithelial neoplasia of the vulva and vagina / Petry, K.U. -- Penile cancer and penile intraepithelial neoplasia / Gross, G. -- Anal cancer and intraepithelial neoplasia / Wieland, U. ; Kreuter, A. -- Tonsillar cancer / Klussmann, J.P.; Wagner, S.; Wittekindt, C. -- Cytology / Ikenberg, H. -- Concepts of biomarker development / von Knebel Doeberitz, M.; Vinokurova, S.; Reuschenbach, M. -- Detection of human papillomavirus DNA and RNA / Ikenberg, H. -- Human papillomavirus testing in primary screening for cervical cancer / Petry, K.U. -- Primary prevention by vaccination / Kaufmann, A.M.; Gissmann, L.
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    An orientation to proposal writing -- Definitions -- Types of grant applications -- Components of a proposal -- The process of submitting a proposal -- The difference between grants and contracts -- Organizing the writing -- Writing for an established organization or a new organization -- Writing style and format -- Using technology in proposal development -- The role and use of search engines -- Review of funder's web sites -- Evaluating data and other information -- Electronic submission of the proposal -- Understanding the agency, the community, and the funder -- Understanding the agency -- Understanding the community -- Understanding the funder -- Problem- or needs-based program development -- Understanding the community through data -- Understanding barriers to service -- Program design and theoretical orientations -- Conceptualizing program ideas -- Working with a collaborative -- Sustainability and institutionalization -- Writing the needs or problem statement -- Definitions -- The purpose of the needs/problem statement -- A guide to writing the needs/problem statement -- Writing goals, objectives, and the implementation plan -- Secion one : goals and objectives -- Section two : implementation plan -- Writing the evaluation plan -- The benefits of evaluation -- Developing an evaluation plan -- Writing the evaluation section -- Other evaluation considerations -- Creating the budget -- Types of budgets -- Budgeting for the first-time grant writer -- Other budgeting issues -- Agency capability and finishing touches -- The agency capability statement -- Requesting letters of support -- The proposal abstract -- The title and title page -- The cover letter -- Frequently asked questions (FAQs) -- Appendix A: Estimating time -- Appendix B: Funding resource information -- References and suggested readings -- Index -- About the authors.
  • Mechanistic aspects of COX-2 expression in colorectal neoplasia -- Mode of action of aspirin as a chemopreventive agent -- Coxibs: pharmacology, toxicity and efficacy in cancer clinical trials -- COX-2 active agents in the chemoprevention of colorectal cancer -- New NSAID targets and derivatives for colorectal cancer chemoprevention -- Aspirin in prevention of sporadic colorectal cancer: current clinical evidence and overall balance of risks and benefits -- Nutritional agents with anti-inflammatory properties in chemoprevention of colorectal neoplasia -- Genetics, inheritance and strategies for prevention in populations at high risk of colorectal cancer (CRC).
  • The book entitled "Prospects in Bioscience: Addressing the issues" is a collection of selected research papers presented at the International Conference on Advances in Biological Sciences (ICABS) organized by the Department of Biotechnology and Microbiology and the Inter University Centre for Bioscience, Kannur University, Kerala, India. ICABS witnessed a unique spectrum of Scientific Programmes on the most recent and exciting developments in modern biology. The conference displayed the numerous breakthroughs and significant developments in the important areas of modern biology and their relevance to the welfare of global society. The Book contains 50 well written chapters, each one discussing scientifically organized findings of original research work done in reputed laboratories. Needless to say, they deal with advances in various disciplines of modern biology including Cell and Molecular Biology, Structural Biology, Industrial and Environmental Biotechnology, Food and Agricultural Biotechnology and Medical Biotechnology. As the title rightly indicates, the chapters project the prospects in the respective areas and the issues in them. Specific issues discussed in the book includes development of transgenic plants, bioremediation of toxic industrial effluents, biotransformation for novel antibiotics, biofertilizer development, molecular drug designing and structure elucidation, molecular identification of pathogens, production of anti microbials, biocontrol agents and bioactive molecules, cancer biology, plant breeding and hybrid seed production etc. The book with its contents spreading across the vast arena of modern biology is expected to cater to the need of researchers, technologists and students.
  • Defining the problem : from subclinical disease to clinically insignificant prostate cancer / Wael Sakr -- What every patient should know about prostate cancer before he submits to biopsy of his prostate / Thomas A. Stamey, Rosalie Nolley, and Dorothea Torti -- Prostate-specific antigen and prostate cancer screening / Stacy Loeb, Misop Han, and William J. Catalona -- The role of complexed prostate-specific antigen in prostate cancer screening / Matthew E. Nielsen and Alan W. Partin -- Newly recognized forms of prostate-specific antigen and emerging molecular markers / Eduardo I. Canto and Kevin M. Slawin -- The role of prostate-specific antigen velocity in the diagnosis and management of prostate cancer / H. Ballentine Carter -- Prostate cancer screening : navigating the controversy / Timothy C. Brand and Ian M. Thompson -- Prostate cancer nomograms and how they measure up to neural networks / Pierre I. Karakiewicz and Michael W. Kattan -- Preparation for prostate biopsy / Alan M. Nieder and Mark S. Soloway -- Principles of prostate ultrasound / Martha K. Terris -- Minimizing pain and optimizing patient experience during prostate biopsy / J. Stephen Jones -- Prostate biopsy techniques / Katsuto Shinohara -- Biopsy strategies-how many and where? / Joseph C. Presti, Jr. -- Transperineal prostate biopsy / Paolo Emiliozzi and Vito Pansadoro -- Repeat prostate biopsies and the Vienna nomograms / Bob Djavan and Sibylle Marihart -- Saturation biopsy for detection and characterization of prostate cancer / J. Stephen Jones -- Pathologic implications of prostate biopsy / Ming Zhou and Cristina Magi-Galluzzi -- Complications of transrectal ultrasound-guided prostate biopsy / Sam S. Chang and Michael S. Cookson -- Management and controversies of high-grade prostatic intraepithelial neoplasia and atypical small acinar proliferation on prostate biopsy / Alon Z. Weizer ... [et al.] -- Future directions in prostate cancer diagnosis / Nicholas J. Fitzsimons ... [et al.]
  • Anatomy and Normal Histology of the Prostate Pertinent to Biopsy Practice -- Prostate Needle Biopsy Sampling Techniques: Impact on Pathological Diagnosis -- Diagnosis of Limited Cancer in Prostate Biopsy -- Immunohistochemistry in Prostate Biopsy Evaluation -- Contemporary Approach to Gleason Grading of Prostate Cancer -- Histologic Variants of Prostate Carcinoma -- Benign Mimics of Prostate Carcinoma -- Atypical Cribriform Lesions of the Prostate Gland: Emerging Concepts of Intraductal Carcinoma of the Prostate (IDC-P) -- High-Grade Prostatic Intraepithelial Neoplasia -- Atypical Glands Suspicious for Cancer -- Spindle Cell Lesions of the Prostate Gland -- Treatment Effect in Benign and Malignant Prostate Tissue -- Molecular Biology of Prostate Cancer and Emerging Diagnostic and Prognostic Biomarkers -- Biopsy Specimen Handling, Processing, Quality Assurance Program -- Reporting of Prostate Biopsy.
  • Prostate cancer 2010, ClinicalKey
    Each volume in the Early Detection and Treatment of Cancer Series is packed with practical, authoritative information designed to cover the full range of diagnostic procedures, including pathologic, radiologic, bronchoscopic, and surgical aspects. You'll be able to determine the safest, shortest, least invasive way to reach an accurate diagnosis; stage the disease; and choose the best initial treatment for early stages. Based on current evidence in the literature, authors provide clinical, hands-on tools to help you make informed decisions on precisely what tests and imaging studies are needed to diagnose and stage each type of cancer. Practical, authoritative, and highly-illustrated, this volume in the brand new Early Detection and Treatment of Cancer series covers current protocols and the latest advances in diagnostic imaging and molecular and serologic markers for prostate cancer. Apply expert advice on the best "next-step" plan for different presentations and tips for less invasive protocols. Get clinical, hands-on tools to help you make informed decisions on precisely what tests and imaging studies are needed for accurate diagnosis and staging. Clear figures, tables, and boxes illustrate step-by-step care of the full range of problems encountered.
  • Prostate cancer 2007, Springer
  • Cell biology. Stem cells in the normal and malignant prostate / Norman J. Maitland -- Role of reactive stroma in prostate cancer / Rebeca San Martin, David R. Rowley -- The role of cholesterol in prostate cancer / Keith R. Solomon, Kristine Pelton, Michael R. Freeman -- Genetics. PTEN in prostate cancer / Marcus A. Ruscetti, Hong Wu -- ETS fusion genes in prostate cancer / J. Chad Brenner, Arul M. Chinnaiyan, Scott A. Tomlins -- Cell signaling. Signaling mechanisms of Vav3, a guanine nucleotide exchange factor and androgen receptor coactivator, in physiology and prostate cancer progression / Leah S. Lyons, Kerry L. Burnstein -- Transforming growth factor-beta in prostate cancer / David Danielpour -- The p38 MAPK pathway in prostate cancer / Daniel Djakiew -- NF-kappaB2/p52 in prostate cancer / Nagalakshmi Nadiminty, Ramakumar Tummala, Yezi Zhu -- The functional role of DAB2IP, a homeostatic factor, in prostate cancer / Eun-Jin Yun, Kaijie Wu, Yuh-Shyan Tsai -- Tyrosine kinases in prostate cancer / Yun Qiu, Dhanraj Deshmukh -- Human prostatic acid phosphatase in prostate carcinogenesis / Sakthivel Muniyan, Yu-Wei Chou, Shou-Qiang Ou-Yang -- Hormonal. Truncated androgen receptor splice variants in prostate cancer / Peter E. Lonergan, Donald J. Tindall -- Biology and clinical relevance of estrogen receptors in prostate cancer / Shuk-Mei Ho, Pheruza Tarapore, Ming-Tsung Lee, and Yuet-Kin Leung -- Vitamin D and prostate cancer / Jung-Sun Kim, Justin M. Roberts, Nancy L. Weigel -- HDAC6 regulation of androgen signaling in prostate cancer / Junkui Ai, Zhou Wang -- Beyond the cell cycle : implications of D-type cyclin deregulation in prostate cancer / Michael A. Augello, William F. Ostrander Jr., Karen E. Knudsen -- Cell death. Role of par-4 in prostate cancer / Nidhi Shukla, Nikhil K. Hebbar, Vivek M. Rangnekar -- Autophagy and prostate cancer therapeutics / Hsing-Jien Kung, Chun Changou, Hao G. Nguyen, Joy C. Yang, Christopher P. Evans, Richard J. Bold, and Frank Chuang.
  • Xenograft models of human prostate cancer -- The pathology of human prostatic atrophy and inflammation -- Tissue microarrays in prostate cancer research -- Prostate (cancer) stem cells -- Cancer-host interactions: a paradigm shift brings new understanding and new opportunities -- Androgen receptor function in prostate cancer progression -- Hedgehog signaling in development and cancer -- Cholesterol, cell signaling, and prostate cancer -- Gene therapy for advanced prostate cancer -- Role of transforming growth factor-ss in immunotherapy of prostate cancer -- Biology and therapeutic basis of prostate cancer bone metastasis -- Molecular imaging: noninvasive strategies to visualize gene expression in living subjects -- Quantum dot nanotechnology for prostate cancer research -- Expression profiling of prostate cancer progression -- Somatic alterations in prostate cancer progression -- Linkage studies of prostate cancer families to identify susceptibility genes -- Somatic DNA methylation changes and prostatic carcinogenesis -- Telomeres, telomerase, chromosome stability, and prostate cancer -- Racial differences in prostate cancer mortality -- Radiotherapy for the treatment of locally advanced prostate cancer -- Recombinant antibody candidates for treatment of prostate cancer -- Differentiation agents and epigenomic therapies: an overview and potential use for prostate cancer -- Taxane-based chemotherapy for prostate cancer -- Co-targeting therapeutics for hormone refractory prostate cancer -- Intercellular targets of prostate cancer -- Novel and efficient translational clinical trial designs in advanced prostate cancer.
  • Based on the highly successful first edition of Prostate Biopsy: Indications, Techniques, and Complications, this new volume presents new concepts that have emerged in answer to current questions from its audience. Many new perspectives and technologies are presented, many from the authors' internationally recognized work on the topic. Substantial developments in techniques and complications are explored in detail. The chapter authors comprise a complete spectrum of specialists in their respective subject areas. All authors are internationally accepted as the premier authorities on their chosen topics. Prostate Cancer Diagnosis: PSA, Biopsy, and Beyond presents new data on the controversial issue of PSA screening and thresholds as indication to perform biopsy. Office based transrectal saturation biopsy is covered in detail. Other topics explored include template guided biopsy and image-guided biopsy as well as a completely new paradigm for prevention of complications.Prostate Cancer Diagnosis: PSA, Biopsy, and Beyond will be of great value and utility to all practicing urologists.
  • Prostate cancer is by far the most common cancer in men and the second leading cause of death due to cancer. It comprises a mixed group of tumours displaying varying clinical behaviour: while some have a very aggressive course, others are rather indolent. Prevention of prostate cancer and discrimination between aggressive and indolent forms are important clinical goals, and the acquisition of significant new evidence on means of achieving these aims makes this book particularly timely. A wide range of topics are covered by leading authorities in the field. The biology and natural history of prostate cancer are reviewed, and the role of lifestyle and dietary factors, assessed. Detailed attention is paid to risk prediction biomarkers and to the role of novel high-throughput nucleic acid-based technologies in improving risk prediction and thereby allowing tailored approaches to cancer prevention. Potential means of chemoprevention of prostate cancer are also reviewed in depth, covering the very positive new data on the impact of aspirin as well as evidence regarding 5-reductase inhibitors, DFMO, and lycopene. Guidance is provided on the differentiation of aggressive from indolent disease, and the policy and research implications of recent findings are examined. This book will be of interest to both clinicians and researchers.
  • Histopathology and molecular biology of prostate atrophy: a lesion associated with inflammation, prostate intraepithelial neoplasia, and prostate cancer -- Epigenetic gene silencing in prostate cancer -- Inherited genetic changes in prostate cancer -- Prostate molecular oncogenesis: gene deletions and somatic mutations -- Somatic genetic changes in prostate cancer: androgen receptor alterations -- Androgen receptor in prostate cancer progression -- Epigenetic modification and aceylation of androgen receptor regulate prostate cellular growth -- Estrogen receptor a [alpha] and b [beta] in the regulation of normal and malignant prostate epithelium -- Estrogen action in normal prostate epithelium and in prostate cancer -- Hypoxia-inducible factor 1 in the angiogenesis of prostate cancer -- Signal transduction by the Ras-MAP kinase pathway in prostate cancer progression -- Transcription factors STAT5 and STAT3: survival factors for prostate cancer cells -- Role of P13K-Akt and PTEN in the growth and progression of prostate cancer -- New perspectives in prediction of clinical outcome of prostate cancer; TMPRSS2-ETS gene fusion in prostate cancer -- New directions in radiation therapy of prostate cancer: brachytherapy and intensity-modulated radiation therapy -- The current knowledge of hormonal therapy in the treatment of prostate cancer -- Advances in surgical intervention of porstate cancer: comparison of the benefits and pitfalls of retropubic, perineal, and laparoscopic radical prostatectormy -- Targeted therapy trials for prostate cancer -- New perspectives on chemotherapy in prostate cancer -- Concluding remarks: the future of prostate cancer.
  • Prostate cancer is the commonest male cancer with over 5 million survivors in US alone. Worldwide, the problem is staggering and has attracted significant attention by media, scientists and cancer experts. Significant research, discoveries, innovations and advances in treatment of this cancer have produced voluminous literature which is difficult to synthesize and assimilate by the medical community. Prostate Cancer: A Comprehensive Perspective is a comprehensive and definitive source which neatly resolves this problem. It covers relevant literature by leading experts in basic science, molecular biology, epidemiology, cancer prevention, cellular imaging, staging, treatment, targeted therapeutics and innovative technologies. Prostate Cancer: A Comprehensive Perspective, is a valuable and timely resource for urologists and oncologists.
  • The aim of this book will be to contribute to the education of a new generation of experts in urology, molecular biology, pathology and oncology, offering them sufficient knowledge in basic and translational research to be fluency in the web of interacting networks playing a role in prostate cancer development, progression, metastasis and drug-resistance. The volume will cover the latest innovative researches in prostate cancer, with particular emphasis to the state-of-the-art analysis technologies that are essential for the accurate identification of molecular targets for disease diagnosis, molecular mechanisms of tumorigenesis, markers for susceptibility, molecular-based prognostic prevision, characterization of biomarkers of drug efficacy and drug resistance, validation of new therapeutics and diagnostics. Current advancements on the intersecting data concerning transcriptomes, proteomes, and the molecular techniques referred as "omes, will be reported and discussed.
  • 1. Delineating protease functions during cancer development / Nesrine I. Affara, Pauline Andreu, and Lisa M. Coussens -- 2. Proteolytic systems: constructing degradomes / Gonzalo R. Ordóñez ... [et al.] -- 3. Microarrays for protease detection in tissues and cells / Kamiar Moin ... [et al.] -- 4. Positional scanning synthetic combinatorial libraries for substrate profiling / Eric L. Schneider and Charles S. Craik -- 5. Mixture-based peptide libraries for identifying protease cleavage motifs / Benjamin E. Turk -- 6. High throughput substrate phage display for protease profiling / Boris Ratnikov, Piotr Cieplak, and Jeffrey W. Smith -- 7. Imaging specific cell surface protease activity in living cells using reengineered bacterial cytotoxins / John P. Hobson ... [et al.] -- 8. Cell-based identification of natural substrates and cleavage-sites for extracellular proteases by SILAC proteomics / Magda Gioia, Leonard J. Foster, and Christopher M. Overall -- 9. Optical proteolytic beacons for in vivo detection of matrix metalloproteinase activity -- J. Oliver McIntyre and Lynn M. Matrisian -- 10. Dissecting the urokinase activation pathway using urokinase-activated anthrax toxin / Shihui Liu ... [et al.] -- 11. On-demand cleavable linkers for radioimmunotherapy / Pappanaicken R. Kumaresan, Juntao Luo, and Kit S. Lam.
  • Proteases in biology and disease v. 3-, 2005-, Springer
  • 1. Protease-Activated Receptors in Gastrointestinal Function and Disease / Nigel W. Bunnett and Graeme S. Cottrell -- 2. Matrix Metalloproteinases in Gastric Cancer / Nikhil I. Khushalani and Nithya Ramnath -- 3. Proteases in Helicobacter pylori-Mediated Diseases / Thomas Wex, Michael Zack, and Peter Malfertheiner -- 4. Proteases in Pancreatic Disease / Avinash Sewpaul, Jeremy J. French, and Richard M. Charnley -- 5. PAR in the Pathogenesis of Pain in Pancreatic Disease / Pankaj J. Pasricha -- 6. Importance of the Local Renin-Angiotensin System in Pancreatic Disease / Po Sing Leung -- 7. Hepatitis C Viral Proteases And Inhibitors / Mingjun Huang, Avinash Phadke and Atul Agarwal -- 8. Angiotensin Converting Enzyme in the Pathophysiology of Liver Fibrosis / Yao Hong Wei -- 9. Matrix Metalloproteinases in Chronic Liver Disease and Liver Transplantation / Hein W. Verspaget, Johan P. Kuyvenhoven, Cornelis F.M. Sier, Bart van Hoek -- 10. MMPs and ADAMs in Inflammatory Bowel Disease / Alicja Wiercinska-Drapalo, Jerzy Jaroszewicz, Anna Parfieniuk, Anna Moniuszko -- 11. Chemokines and Matrix Metalloproteinases in Colorectal Cancer / Gayle G. Vaday and Stanley Zucker -- 12. Angiotensin-Converting Enzyme (ACE) in Gut Inflammation / Fernando Magro -- 13. Intestinal Apical Protein Transport in Health and Disease / Stephan von Hörsten, Michael Krahn, Nadine Frerker, Anja Gemeinhardt, Dennis Schwab, Silvia Slesiona, Hassan Naim, and Marwan Alfalah.
  • In view of rapidly growing research in the deregulation of proteases and their impact in human health and diseases, this book will highlight existing and emerging research in this exciting area. In-depth critical state-of-the-art reviews will be written by established investigators on proteases dysfunctions associated with pathogenesis of different diseases that are known to occur due to deregulation of proteolytic systems. Multidisciplinary approaches demonstrating biochemical and signal transduction mechanisms associated with deregulation of proteases leading to manifestation of the diseases.
  • Proteases in the brain 2005, Springer
  • Print Material
  • Introduction and technical survey: Protein aggregation and fibrillogenesis -- Fibril formation by short synthetic peptides -- In vitrooligomerization and fibrillogenesis of amyloid-beta peptides -- Tau fibrillogenesis -- Prion protein aggregation and fibrillogenesisin vitro -- Alpha-synuclein aggregation and modulating factors -- Pathological self-aggregation of [beta](2)-microglobulin: A challenge for protein biophysics -- Islet amyloid polypeptide: Aggregation and fibrillogenesisin vitroand its inhibition -- Mechanisms of transthyretin aggregation and toxicity -- Fibrillogenesis of huntingtin and other glutamine containing proteins -- Aggregation and fibrillogenesis of proteins not associated with disease: a few case studies -- Experimental inhibition of peptide fibrillogenesis by synthetic peptides, carbohydrates and drugs -- Experimental inhibition of fibrillogenesis and neurotoxicity by amyloid-beta (abeta) and other disease-related peptides/proteins by plant extracts and herbal compounds -- Alzheimer's disease -- Modeling the polyglutamine aggregation pathway in Huntington's disease: from basic studies to clinical applications -- Parkinson's disease -- Human prion diseases: From kuru to variant Creutzfeldt-Jakob disease -- Animal prion diseases -- [beta](2)-Microglobulin amyloidosis -- Systemic AA amyloidosis -- Familial amyloidotic polyneuropathy and transthyretin -- The challenge of systemic immunoglobulin light-chain amyloidosis (AL).
  • Long-term consequences of early feeding on later obesity risk / Koletzko, B. -- Energy requirements of infants and children / Butte, N.F. -- Protein requirements of infants and children / Garlick, P.J. -- Growth of breast-fed and formula-fed infants / Ziegler, E.E. -- Body composition during the first year of life / Rigo, J. -- Dietary reference intakes : concepts and approaches underlying protein and energy requirements / Yates, A.A. -- Intestinal amino acid metabolism in neonates / Van Goudoever, J.B. ... [et al.] -- Amino acid requirements of infants and children / Pencharz, P.B., Ball, R.O. -- Effects of high protein intakes / Axelsson, I. -- Physiology in food intake regulation : interaction with dietary components / Anderson, G.H., Aziz, A., Abou Samra, R. -- Complementary food : international comparison on protein and energy requirement/intakes / Agostoni, C., Riva, E., Giovannini, M. -- What is the optimal age for introduction of complementary foods? / Dewey, K.G. -- Recent issues in energy-protein malnutrition in children / Desjeux, J.-F. -- Protein quality and quantity in cow's milk-based formula for healthy term infants : past, present and future / Macé, K. ... [et al.] -- Recombinant human milk proteins / Lönnerdal, B. Long-term consequences of early feeding on later obesity risk / B. Koletzko -- Energy requirements of infants and children / N.F. Butte -- Protein requirements of infants and children / P.J. Garlick -- Growth of breast-fed and formula-fed infants / E.E. Ziegler -- Body composition during the first year of life / J. Rigo -- Dietary reference intakes: concepts and approaches underlying protein and energy requirements / A.A. Yates -- Intestinal amino acid metabolism in neonates / J.B. van Goudoever ... [et al.] -- Amino acid requirements of infants and children / P.B. Pencharz, R.O. Ball -- Effects of high protein intakes / I. Axelsson -- Physiology in food intake regulation: interaction with dietary components / G.H. Anderson, A. Aziz, R.A. Samra -- Complementary food: international comparison on protein and energy requirement/intakes / C. Agostoni, E. Riva, M. Giovannini -- What is the optimal age for introduction of complementary foods? / K.G. Dewey -- Recent issues in energy-protein malnutrition in children / J.-F. Desjeux -- Protein quality and quantity in cow's milk-based formula for healthy term infants: past, present and future / K. Macé ... [et al.] -- Recombinant human milk proteins / B. Lönnerdal.
  • A digest of protein purification -- Gel-filtration chromatography -- Immunoaffinity chromatography -- Avoiding proteolysis during protein chromatography -- Scale-up of protein purification : Downstream processing issues -- Phage display : A powerful technology for the generation of high specificity affinity reagents from alternative immune sources -- Engineering protein stability -- Microfluidics in protein chromatography -- Tagging recombinant proteins to enhance solubility and aid purification -- Storage and lyophilisation of pure proteins -- Differential precipitation and solubilization of proteins -- Ion-exchange chromatography : Basic principles and application to the partial purification of soluble mammalian prolyl oligopeptidase -- Protein quantitation and analysis of purity -- Purification of proteins fused to glutathione S-transferase -- Purification of proteins fused to maltose-binding protein -- Purification of proteins from baculovirus-infected insect cells -- Purification of poly-histidine-tagged proteins -- Immobilized metal affinity chromatography/reversed-phase enrichment of phosphopeptides and analysis by cid/etd tandem mass spectrometry -- Tag removal by site-specific cleavage of recombinant fusion proteins -- Purification of antibodies using affinity chromatography -- Optimized generation of high-affinity, high-specificity single-chain Fv antibodies from multiantigen immunized chickens -- Measuring protein-protein interactions using biacore -- Ultra-performance liquid chromatography-mass spectrometry of proteins -- Hydrophobic interaction chromatography -- Fast protein liquid chromatography -- Shotgun proteomics : A qualitative approach applying isoelectric focusing on immobilized pH gradient and LC-MS/MS -- Shotgun proteomics : A relative quantitative approach using off-gel electrophoresis and LC-MS/MS -- Clinical proteomics : Liquid chromatography-mass spectrometry purification systems -- Strategies for the purification of membrane proteins -- A multi-step chromatographic strategy to purify three fungal endo-[beta]-glucanases.
  • "This book discusses how biological molecules exert their function and regulate biological processes, with a clear focus on how conformational dynamics of proteins are critical in this respect. In the last decade, the advancements in computational biology, nuclear magnetic resonance including paramagnetic relaxation enhancement, and fluorescence-based ensemble/single-molecule techniques have shown that biological molecules (proteins, DNAs and RNAs) fluctuate under equilibrium conditions. The conformational and energetic spaces that these fluctuations explore likely contain active conformations that are critical for their function. More interestingly, these fluctuations can respond actively to external cues, which introduces layers of tight regulation on the biological processes that they dictate. A growing number of studies have suggested that conformational dynamics of proteins govern their role in regulating biological functions, examples of this regulation can be found in signal transduction, molecular recognition, apoptosis, protein / ion / other molecules translocation and gene expression"--Publisher's description.
  • Physiological pathways of PAD activity and citrullinated epitope generation -- from citrullination to specific immunity and disease in rheumatoid arthritis -- The role of citrullinated proteins in the pathophysiology of rheumatoid arthritis -- Protein citrullination: the link between rheumatoid arthritis and periodontitis? -- From genes and environment to anti-culture immunity in rheumatoid arthritis: The role of the lungs -- Neutrophils and their contribution to autoimmunity in rheumatoid arthritis -- Deimination in skin and regulation of PAD expression in keratinocytes -- Importance of citrullination on hair protein molecular assembly during trichocytic differentiation -- Deimination in the peripheral nervous system: A wallflower existence -- Deimination in multiple sclerosis and experimental autoimmune encephalomyelitis -- Protein hypercitrullination in CNS demyelinating disease reversed by PAD inhibition -- Deimination in prion diseases -- Deimination in Alzheimer's disease -- Ongoing studies of deimination in neurodegenerative diseases using the F95 antibody -- The role of protein deimination in epigenetics -- Identifying citrullination sites by mass spectroscopy -- Homocitrulline\U+2014\an analogue and confounder related to citrulline -- Picking the PAD lock: Chemical and biological approaches to identify PAD substrates and inhibitors.
  • Protein design methods and applications 2006, Springer Protocols
    Design of structural elementary motifs. Structure and stability of the [alpha]-helix: lessons for design / Neil Errington, Teuku Iqbalsyah, and Andrew J. Doig. De novo design of monomeric [beta]-hairpin and [beta]-sheet peptides / David Pantoja-Uceda, Clara M. Santiveri, and M. Angeles Jiménez. De novo proteins from binary-patterned combinatorial libraries / Luke H. Bradley, Peter P. Thumfort, and Michael H. Hecht. Non-protein amino acids in the design of secondary structure scaffolds / Radhakrishnan Mahalakshmi and Padmanabhan Balaram. Design and synthesis of [beta]-peptides with biological activity / Marc J. Koyack and Richard P. Cheng -- Design of entire proteins and protein complexes. Design of miniproteins by the transfer of active sites onto small-size scaffolds / Franc̦ois Stricher, Loïc Martin, and Claudio Vita. Consensus design as a tool for engineering repeat proteins / Tommi Kajander, Aitziber L. Cortajarena, and Lynne Regan. Multiple sequence alignment as a guideline for protein engineering strategies / Alan R. Davidson. Sequence search methods and scoring functions for the design of protein structures / Hocine Madaoui, Emmanuelle Becker, and Raphael Guerois. Prediction of protein-protein interaction based on structure / Gregorio Fernandez-Ballester and Luis Serrano. Electrostatic design of protein-protein association rates / Gideon Schreiber, Yossi Shaul, and Kay E. Gottschalk -- Design of amyloidogenic polypeptides and amyloid inhibitors. Peptide model systems for amyloid fiber formation: design strategies and validation methods / Alexandra Esteras-Chopo, María Teresa Pastor, and Manuela López de la Paz. Protein misfolding disorders and rational design of antimisfolding agents / Lisbell D. Estrada, June Yowtak, and Claudio Soto.
  • Protein engineering 2009, Springer
    Understanding enzyme mechanism through protein chimeragenesis / N.M. Goodey and S.J. Benkovic -- Chemical protein engineering : synthetic and semisynthetic peptides and proteins / L. Merkel, L. Moroder, and N. Budisa -- Native chemical ligation: Semisynthesis of post-translationally modified proteins and biological probes / E. Vogel Taylor and B. Imperiali -- Chemical methods for mimicking post-translational modifications / S.I. van Kasteren, P. Garnier and B.G. Davis -- Noncanonical amino acids in protein science and engineering / K.E. Beatty and D.A. Tirrell -- Fidelity mechanisms of the aminoacyl-tRNA synthetases / A.P. Mascarenhas ... [et al.] -- Specialized components of the translational machinery for unnatural amino acid mutagenesis : tRNAs, aminoacyl-tRNA synthetases, and ribosomes / C. Köhrer and U.L. RajBhandary -- In vivo studies of receptors and ion channels with unnatural amino acids / D.A. Dougherty -- Synthesis of modified proteins using misacylated tRNAs / S.M. Hecht -- Cell-free synthesis of proteins with unnatural amino acids. The pure system and expansion of the genetic code / I. Hirao, T. Kanamori and T. Ueda -- Engineering nucleobases and polymerases for an expanded genetic alphabet / A.M. Leconte and F.E. Romesberg -- Understanding membrane proteins. How to design inhibitors of transmembrane protein-protein interactions / J.S. Slusky, H. Yin and W.F. DeGrado.
  • "Experimental protein engineering and computational protein design are broad but complementary strategies for developing proteins with altered or novel structural properties and biological functions. By describing cutting-edge advances in both of these fields, Protein Engineering and Design aims to cultivate a synergistic approach to protein science. The first half of the book discusses experimental approaches to protein engineering and starts by describing several high-throughput screening platforms for protein engineering. Key techniques used for diversity generation are also discussed. The next few chapters present examples of therapeutics, enzymes, biomaterials, and other proteins that have been engineered by rational or combinatorial approaches. The section finishes with a chapter on the use of non-natural amino acids in protein engineering. The second half of the book introduces computational protein design, beginning with a chapter on computational and informatics algorithms used in protein engineering. Core components of computational protein design are then discussed in detail, and examples of heuristic protein design are provided. Subsequent chapters present examples of how computational design has played a critical role in advancing the field of protein engineering. Concluding with a chapter outlining current challenges in the field, this book makes computational protein design and diversity-oriented protein engineering widely accessible to a broad audience in academia and industry alike."--Publisher's description.
  • pt. B ScienceDirect
  • Protein engineering protocols 2006, Springer Protocols
  • Introduction -- Structure of proteins -- Physical interactions that determine the properties of proteins -- Calculation of the kinetic rate constants -- High kinetic resolution of protein folding events -- Kinetic methods for slow reactions -- Resolution of protein structures in solution -- High structural resolution of transient protein conformations -- Experimental problems of the kinetic and structural resolution of reactions that involve proteins -- The folding pathway of protein (barstar) at the resolution of individual residues from microseconds to seconds -- Highly resolved folding pathways and mechanisms of six proteins -- Structural determinants of the rate of protein folding -- Evolutionary computer programming of protein structure and folding.
  • Protein folding protocols 2006, Springer Protocols
  • Protein kinase C in cancer signaling and therapy: introduction and historical perspective -- Regulation of conventional and novel protein kinase C isozymes by phosphorylation and lipids -- Phorbol esters and diacylglycerol: the PKC activators -- Diacylglycerol signaling: the C1 domain, generation of DAG and termination of signals -- Regulation of PKC by protein-protein interaction in cancer -- Introduction: PKC isozymes in the control of cell function -- Regulation and function of protein kinase C signaling -- PKC and control of the cell cycle -- PKC and the control of apoptosis -- Atypical PKC's, NF-kB and inflammation -- Introduction: PKC and cancer -- Protein kinase C, p53, and DNA damage -- PKCs as mediators of the hedgehog and Wnt signaling pathways -- PKC-PKD interplay in cancer -- Transgenic mouse models to investigate functional specificity of protein kinase C isoforms in the development of squamous cell carcinoma, a nonmelanoma human skin cancer -- PKC isozymes and skin cancer -- PKC and breast cancer -- PKC and prostate cancer -- Protein kinase C and lung cancer -- Introduction [PKC isozymes as targets for cancer therapy] -- PKC and resistance to chemotherapeutic agents -- PKCd as a target for chemotherapeutic drugs -- Atypical PKCs as targets for cancer therapy.
  • Catalytic mechanisms and regulation of protein kinases / Zhihong Wang and Philip A. Cole -- A structural atlas of kinases inhibited by clinically approved drugs / Qi Wang, Julie A. Zorn, and John Kuriyan -- Fragment-based approaches to the discovery of kinase inhibitors / Paul N. Mortenson, Valerio Berdini, and Marc O'Reilly -- Targeting protein kinases with selective and semi-promiscuous covalent inhibitors / Rand M. Miller and Jack Taunton -- The resistance tetrad: amino acid hotspots for kinome-wide exploitation of drug-resistant protein kinase alleles / Fiona P. Bailey, Veselin I. Andreev, and Patrick A. Eyers -- FLiK: a direct binding assay for the identification and kinetic characterization of stabilizers of inactive kinase conformations / Jeffrey R. Simar and Daniel Rauh -- Discovery of allosteric BCR-ABL inhibitors from phenotypic screen to clinical candidate / Nathanael S. Gray and Doriano Fabbro -- The logic and design of analog-sensitive kinases and their small molecule inhibitors / Michael S. Lopez, Joseph I. Kliegman, and Kevan M. Shokat.
  • Protein kinase protocols Springer Protocols
  • Synthesis, modification, and turnover of proteins during aging / Suresh I.S. Rattan -- Regulation of mRNA translation as a conserved mechanism of longevity control / Ranjana Mehta ... [et al.] -- Protein synthesis and the antagonistic pleiotropy hypothesis of aging / Pankaj Kapahi -- Proteasome function determines cellular homeostasis and the rate of aging / Niki Chondrogianni and Efstathios S. Gonos -- Autophagy and longevity : lessons from C. elegans / Kailiang Jia and Beth Levine -- Autophagy and aging : lessons from progeria models / Guillermo Mario, Alvaro F. Fernandez and Carlos Lopez-Oton -- Regulation of protein turnover by longevity pathways / Tibor Vellai and Krisztina Takocs-Vellai -- Protein metabolism and lifespan in Caenorhabditis elegans / Geert Depuydt, Jacques R. Vanfleteren, and Bart P. Braeckman -- Mitochondrial protein quality control systems in aging and disease / Karin Luce, Andrea C. Weil, and Heinz D. Osiewacz -- p38MAPK in the senescence of human and murine fibroblasts / Florence Debacq-Chainiaux ... [et al.] -- Protein homeostasis in models of aging and age related conformational disease / Elise A. Kikis, Tali Gidalevitz, and Richard I. Morimoto -- Roles for SUMO modification during senescence / Artemisia M. Andreou and Nektarios Tavernarakis -- Post-translational modification of cellular proteins by ubiquitin and ubiquitin-like molecules : role in cellular senescence and aging / Johannes Grillari, Regina Grillari-Voglauer, and Pidder Jansen-Dorr -- Sensory influence on homeostasis and lifespan : molecules and circuits / Joy Alcedo, Wolfgang Maier, and Queelim Ch'ng -- Regulation of muscle atrophy in aging and disease / Manlio Vinciguerra, Antonio Musaro, and Nadia Rosenthal -- Confronting cellular heterogeneity in studies of protein metabolism and homeostasis in aging research / Louise Boisen and Peter Kristensen.
  • Protein misfolding and celluar stress : an overview / Niels Gregersen and Peter Bross -- Protein aggregation diseases : toxicity of soluble prefibrillar aggregates and their clinical significance / Massimo Stefani -- Consequences of stress in the secretary pathway : the ER stress response and its role in the metabolic syndrome / Martin Schröder and Louise Sutcliffe -- What role does mitochondrial stress play in neurodegenerative diseases? / Alicia Mae Pickrell and Carlos Torres Moraes -- Autophagy in disease / Dalibor Mijaljica, Mark Prescott, and Rodney J. Devenish -- Mitophagy and mitoptosis in disease processes / Dalibor Mijaljica, Mark Prescott, and Rodney J. Devenish -- Cellular stress and protein misfolding during aging / Rajiv Vaid Basaiawmoit and Suresh I.S. Rattan -- Measuring consequences of protein misfolding and cellular stress using OMICS techniques / Peter Bross ... [et al.] -- Production of cells with targeted integration of gene variants of human ABC transporter for stable and regulated expression using the Flp recombinase system / Kanako Wakabayashi-Nakao ... [et al.] -- Stress response profile in human fribroblasts exposed to heat shock or oxidative stress / Christina Bak Pedersen and Niels Gregersen -- Examining ubiquitinated protein aggregates in tissue sections / Natalia A. Kaniuk and John H. Brumell -- Determination of proteasomal activities / Cristovao F. Lima and Suresh I.S. Rattan -- Measurement of autophagy in cells and tissues / Isei Tanida and Satoshi Waguri -- Transcription factor sequestration by polyglutamine proteins / Tomoyuki Yamanaka and Nobuyuki Nukina -- Biological membranes as protein aggregation matrices and targets of amyloid toxicity / Monica Bucciantini and Cristina Cecchi -- Measurement of mitochondrial ROS production / Anatoly A. Starkov -- In vivo detection of oxidized proteins : a practical approach to tissue-derived mitochondria / Francesca Maltecca and Giorgio Casari -- Measurement of oxidized/reduced glutathione ratio / Joshua B. Owen and D. Allan Butterfield -- Determination of altered mitochondria ultrastructure by electron microscopy / Shoichi Sasaki -- Assessing bad sub-cellular localization under conditions associated with prevention or promotion of mitochondrial permeability transition-dependent toxicity / Liana Cerioni and Orazio Cantoni -- A cellular viability assay to monitor drug toxicity / Jakob Hansen and Peter Bross -- Rescue of misfolded proteins and stabilization by small molecules / Raymond C. Stevens, javier Sancho, and Aurora Martinez.
  • Protein folding and misfolding, relevance to disease, and biological function / Massimo Stefani -- Alzheimer's disease / Charlotte E. Teunissen and Tischa J.M. van der Cammen -- Improving cholinergic transmission -- Cholinergic transmission and acetylcholine release enhancers / Pierre Francotte, Pascal de Tullio, and Bernard Pirotte -- AChE and its inhibition / Jure Stojan -- AChE inhibitors and their clinical assessment / Pierre Francotte, Pascal de Tullio, and Bernard Pirotte -- Reduction in plaque formation -- Secretase and APP processing / Christian Czech, Helmut Jacobsen, and Celine Adessi -- Mechanism of plaque formation and A[B] aggregation inhibitors / Christian Czech, Helmut Jacobsen, and Celine Adessi -- Nonsteroidal anti-inflammatory drugs / Bruno P. Imbimbo and Francesca Speroni -- 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors / Dario Cattaneo -- A[B] polymerization reduction / Harry LeVine III and Corrine E. Augelli-Szafran -- Carbonic anhydrase activators as potential anti-Alzheimer's disease agents / Claudiu T. Supuran and Andrea Scozzafava -- Detection and reduction of neurofibrillary lesions / Jeff Kuret -- Protein misfolding in Alzheimer disease : pathogenic or protective? / Rudy J. Castellani ... [et al.] -- Enhancement of brain retinoic acid levels / Ann B. Goodman ... [et al.] -- Parkinson's disease : what is it? what causes it? and how can it be cured? / Tom Foltynie, Andrew W. Michell, and Roger A. Barker -- Restoring dopamine levels / P. Nuno Palma .. [et al.] -- Huntington's disease / Claire-Anne Gutekunst and Fran Norflus -- Amyotrophic lateral sclerosis (motor neuron disease) / Teresa Sanelli ... [et al.] -- Transmissible spongiform encephalopathies / Michael D. Geschwind and Giuseppe Legname -- Overview / H. John Smith, Robert D.E. Sewell, and Claire Simons.
  • Protein translocation across the endoplasmic reticulum membrane / Ramanujan S. Hegde -- Preprotein translocation through the sec translocon in bacteria / Antoine P. Maillard, Kenneth K.Y. Chan, and Franck Duong -- Protein translocation in archaea / Jerry Eichler -- Structure of the SecYEG protein translocation complex / Ian Collinson -- Membrane protein insertion in bacteria from a structural perspective / Mark Paetzel and Ross E. Dalbey -- The twin-arginine transport system / Frank Sargent, Ben C. Berks, and Tracy Palmer -- Retro-translocation of proteins across the endoplasmic reticulum membrane / J. Michael Lord and Lynne M. Roberts -- Chloroplast protein targeting: multiple pathways for a complex organelle / Matthew D. Smith and Danny J. Schnell -- The mitochondrial protein import machinery / Doron Rapaport -- Import of proteins into peroxisomes / Sven Thoms and Ralf Erdmann.
  • Protein nanotechnology: the new frontier in biosciences / Tuan Vo-Dinh -- Kinetics and mechanisms of protein crystallization at the molecular level / Peter G. Vekilov -- Nanostructured systems for biological materials / Esther H. Lan, Bruce Dunn, and Jeffrey I. Zink -- Nanomaterials of drug delivery systems for tissue regeneration / Yasuhiko Tabata -- Nanotechnology with S-layer proteins / Bernhard Schuster ... [et al.] -- Folding of β-structured fibrous proteins and self-assembling peptides / Anna Mitraki and Mark J. van Raaij -- Application of NMR methods to identify detection reagents for use in development of robust nanosensors / Monique Cosman, Viswanathan V. Krishnan, and Rod Balhorn -- Studying 3D subdomains of proteins at the nanometer scale using fluorescence spectroscopy / Pierre M. Viallet and Tuan Vo-Dinh -- Carbon nanotubes and nanowires for biological sensing / Jun Li, Hou Tee Ng, and Hua Chen -- Carbon nanotube systems to communicate with enzymes / J. Justin Gooding and Joe G. Shapter -- Molecularly imprinted polymers for biomolecular recognition / Alexandra Molinelli, Markus Janotta, and Boris Mizaikoff -- Plasmonics-based nanostructures for surface-enhanced Raman scattering bioanalysis / Tuan Vo-Dinh, Fei Yan, and David L. Stokes -- Bacterial virus [phi]29 DNA-packaging motor and its potential applications in gene therapy and nanotechnology / Peixuan Guo -- Construction of ordered protein arrays / Jarrod Clark ... [et al.] -- Bioengineering and characterization of DNA-protein assemblies floating on supported membranes / Wilfrid Boireau, Anthony C. Duncan, and Denis Pompon -- Nanosystems for biosensing: multianalyte immunoassay on a protein chip / Eiichi Tamiya ... [et al.] -- Optical nanosensors for detecting proteins and biomarkers in individual living cells / Tuan Vo-Dinh -- Nanoelectrodes integrated in atomic force microscopy cantilevers for imaging of in situ enzyme activity / Angelika Kueng ... [et al.] -- Protein amyloidose misfolding: mechanisms, detection, and pathological implications / Nigil Satish, Ajit Sadana, and Tuan Vo-Dinh -- Near-field scanning optical microscopy for bioanalysis at nanometer resolution / Musundi B. Wabuyele ... [et al.].
  • Analysis of protein phosphatases / Shirish Shenolikar -- A brief introduction to the protein phosphatase families / Tomas Mustelin -- Small molecule inhibitors of Ser/thr protein phosphatases / Mark Swingle, Li Ni, and Richard E. Honkanen -- Synthesis and use of the protein phosphatase affinity matrices microcystin- and microcystin-biotin-sepharose / Greg Moorhead, Timothy A.J. Haystead, and Carol MacKintosh -- Utilizing protein phosphatase inhibitors to define PP2A as a regulator of ataxia-telangiectasia mutated (ATM) / Aaron A. Goodarzi ... [et al.] -- An automated, fluorescence-based method for continuous assay of PP2A activity / Adam M. Wegner ... [et al.] -- An in vivo assay to quantify stable protein phosphatase 2A (PP2A) heterotrimeric species / Matthew S. Gentry, Richard L. Hallberg, and David C. Pallas -- Mutagenesis and expression of the scaffolding Aa and Ab subunits of PP2A / Ralf Ruediger, Jin Zhou, and Gernot Walter -- Isolation and characterization of PP2A holoenzymes containing FLAG-tagged B subunits / Deanna G. Adams and Brian E. Wadzinski -- Purification of PP2A holoenzymes by sequential immunoprecipitation with anti-peptide antibodies / Gernot Walter, Jin Zhou, and Ralf Ruediger -- Purification of PP2Ac from bovine heart / Hue T. Tran ... [et al.] -- Visualization of intracellular PP1 targeting through transiently and stably expressed fluorescent protein fusions / Laura Trinkle-Mulcahy ... [et al.] -- Yeast two-hybrid screens to identify drosophila PP1-binding proteins / Daimark Bennett and Luke Alphey -- Identification of cellular protein phosphatase-1 regulators / David W. Roadcap, Matthew H. Brush, and Shirish Shenolikar -- Assay for 3-way interaction of protein phosphatase-1 (Glc7) with regulatory subunits plus phosphatase inhibitor-2 / Masumi Eto and David L. Brautigan -- Phosphorylation of the protein phosphatase type 1 inhibitor protein, CPI-17, by protein kinase C / Michael P. Walsh ... [et al.] -- Purification of smooth muscle myosin phosphatase using a thiophosphorylated myosin light chain-affinity resin / Merideth Borman and Justin MacDonald -- Proteins interacting with saccharomyces cerevisiae type 1 protein phosphatase catalytic subunit identified by single-step affinity purification and mass spectrometry / Edmund P. Walsh ... [et al.] -- Expression of protein histidine phosphatase in Escherichia coli, purification, and determination of enzyme activity / Nicole Bäumer .. [et al.] -- The use of RNA interference to analyze protein phosphatase function in mammalian cells / Iain Fraser ... [et al.] -- Recognition of a PP2C interaction motif in several plant protein kinases / Niranjan Chakraborty, Ohta Masaru, and Jian-Kang Zhu -- The use of yeast genetic tools to define biological roles of novel protein phosphatases / Joaquín Ariño ... [et al.] -- Targeting of PP2C in budding yeast / Irene Ota and James Mapes -- Phosphatase targets in TOR signaling / Estela Jacinto -- Functional characterization of the small CTD phosphatases (SCPs) / Michele Yeo and Patrick S. Lin -- Genome-scale discovery and characterization of class-specific protein sequences / David Kerk -- Yeast substrate-trapping system for isolating substrates of protein tyrosine phosphatases / Masahide Fukada and Masaharu Noda.
  • Protein phosphatases 2003, ScienceDirect
    Section I. Determination, detection, and localization -- Section II. Interacting proteins and subunits -- Section III. Inhibition, stimulation, and modulation of activity -- Section IV. Expression systems -- Section V. Knockdown and knockout technologies.
  • Introduction -- Elementary interactions in and around proteins -- Secondary structures of polypeptide chains -- Protein structures -- Cooperative transitions in protein molecules -- Prediction and design of protein structure -- Physical background of protein functions.
  • Quantitation of proteins -- Electrophoresis of proteins and peptides and detection in gels -- Blotting and detection methods -- Chemical modification of proteins and peptide production and purification -- Posttranslational modifications -- Antibody techniques.
  • The health of the proteome depends upon protein quality control to regulate the proper synthesis, folding., translocation, and clearance of proteins. The cell is challenged constantyl by environmental and physiological stress, aging, and the chronic expressions of disease associated misfolded proteins. Substantial evidence supports the hypothesis that the expression of damaged proteins initiates a cascade of molecular events that leads to Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, and other diseases of protein conformation.
  • An introduction to protein sequencing using tandem mass spectrometry -- The primary structure of proteins and a historical overview of protein sequencing -- Fundamental mass spectrometry -- Collisionally induced dissociation of protonated peptide icons and the interpretation of product ion spectra -- Basic polyacrylamide gel electrophoresis -- The preparation of protein digests for mass spectrometric sequencing experiments -- Mass spectrometric analysis of tryptic digests -- Protein identification by database searching -- Sequence analysis of novel proteins -- The characterization of post-translationally modified proteins using tandem mass spectometry.
  • Protein sequencing protocols. 2nd ed. 2002, Springer Protocols
  • Protein structure prediction. 2nd ed. 2008, Springer Protocols
    A historical perspective of template-based protein structure prediction / Jun-tao Guo, Kyle Ellrott, and Ying Xu -- The assessment of methods for protein structure prediction / Anna Tramontaro ... [et al.] -- Aligning sequences to structures / Liam James McGuffin -- Protein structure prediction using threading / Jinbo Xu, Feng Jiao, and Libo Yu -- Algorithms for multiple protein structure alignment and structure-derived multiple sequence alignment / Maxim Shatsky, Ruth Nussinov, and Haim J. Wolfson -- Indexing protein structures using suffix trees / Feng Gao and Mohammed J. Zaki -- Hidden Markov models for prediction of protein features / Christopher Bystroff and Anders Krogh -- The pros and cons of predicting protein contact maps / Lisa Bartoli ... [et al.] -- Roadmap methods for protein folding / Mark Moll, David Schwarz, and Lydia E. Kavraki -- Scoring functions for de novo protein structure prediction revisited / Shing-Chung Ngan ... [et al.] -- Protein-protein docking : overview and performance analysis / Kevin Wiehe ... [et al.] -- Molecular dynamics simulations of protein folding / Angel E. Garcia.
  • Stabilization of protein structure -- Protein stabilization by naturally occurring osmolytes -- The thermodynamic linkage between protein structure, stability, and function -- Measuring the conformational stability of a protein by hydrogen exchange --Modeling the native state ensemble -- Conformational entropy in protein folding: a guide to estimating conformational entropy via modeling and computation -- Turn scanning: experimental and theoretical approaches to the role of turns -- Laser temperature-jump methods for studying folding dynamics -- Kinetics of conformational fluctuations by EX1 hydrogen exchange in native proteins -- Molecular dynamics simulations of protein unfolding/folding.
  • Introduction/overview -- Ross E. Dalbey, Gunnar von Heijne -- Methods in protein targeting, translocation and transport / Ross E. Dalbey, Minyong Chen, Martin Wiedmann -- Targeting sequences / Gunnar von Heijne -- Protein export in bacteria / Arnold J.M. Driessen, Chris van der Does -- Protein sorting at the membrane of the endoplasmic reticulum / Nora G. Haigh, Arthur E. Johnson -- Membrane protein insertion into bacterial membranes and the endoplasmic reticulum / Andreas Kuhn, Martin Spiess -- Disulfide bond formation in prokaryotes and eukaryotes / James Regeimbal, James C.A. Bardwell -- The unfolded protein response / Carmela Sidrauski, Jason H. Brickner, Peter Walter -- Protein quality control in the export pathway: the endoplasmic reticulum and its cytoplasmic proteasome connection / Zlatka Kostova, Dieter H. Wolf -- Translocation of proteins into mitochondria / Thorsten Prinz, Nikolaus Pfanner, Kaye N. Truscott -- The import and sorting of protein in chloroplasts / Jürgen Soll, Colin Robinson, Lisa Heins -- Import of proteins into peroxisomes / Suresh Subramani ... [et al.] -- Nucleocytoplasmic transport / Dirk Görlich, Stefan Jäkel -- Protein transport to the yeast vacuole / Todd R. Graham, Steven F. Nothwehr -- The secretory pathway / Benjamin S. Glick -- Vesicular transport / Joachim Ostermann, Tobias Stauber, Tommy Nilsson -- Conclusion/perspective / Ross E. Dalbey, Gunnar von Heijne.
  • Protein tyrosine kinases as targets for cancer and other indications / Mark Pearson, Carlos Garcia-Echeverria, Doriano Fabbro -- Inhibitors of signaling interfaces: targeting Src homology 2 domains in drug discovery / Carlos Garcia-Echeverria -- PI 3-kinase inhibition: a target for therapeutic intervention / Peter M. Finan, Stephen G. Ward -- Src as a target for pharmaceutical intervention: potential and limitations / Mira Susa ... [et al.] -- Activated FLT3 receptor tyrosine kinase as a therapeutic target in leukemia / Blanca Scheijen, James D. Griffin -- JAK kinases in leukemias/lymphomas and multiple myeloma / Renate Burger, Martin Gramatzki -- Glivec (Gleevec, Imatinib, STI571): a targeted therapy for CML / Elisabeth Buchdunger, Renaud Capedeville -- Platelet-derived growth factor: normal function, role in disease, and applications of PDGF antagonists / Tobias Sjoblom ... [et al.] -- Structural biology of protein tyrosine kinases / Sandra W. Cowan-Jacob ... [et al.] -- Testing of signal transduction inhibitors in animal models of cancer / Terence O'Reilly, Robert Cozens -- Phosphoproteomics in drug discovery and development / Michel F. Moran.
  • Tyrosine phosphorylation is a rapid and reversible protein modification catalyzed by the yin and yang activities of protein tyrosine kinases (PTKs) and protein tyrosine phosphatases (PTPs). A multitude of PTPs have been implicated in human disease, with a growing number of PTPs now known to play major roles in prevalent metabolic diseases including obesity and type 2 diabetes. Recent studies into PTP function in the context of metabolism highlight the importance of understanding the specific substrates and binding partners of these enzymes, the regulation of PTP activity, and the cell/tissue specificity of PTP functions. This volume contains chapters which highlight many aspects of PTP function in the context of metabolism.
  • This book contains a collection of critical reviews on the expression of biologically functional proteins in Leishmania and Trypanosoma, which was written by renowned researchers on this field. Species belonging to these trypanosomatids genera are etiological agents of leishmaniasis, Chagas' disease and sleeping sickness that are extremely debilitating human infection diseases, which remain a major health problem especially in countries from Latin America, Africa and Middle East. Substantiating the problem, the currently accepted drugs for these diseases are quite unsatisfying due to their low efficacy and high toxicity. In order to solve these real problems, several research groups around the world have become involved in the study and identification of novel potential targets in the trypanosomatid cell. Since proteins are key macromolecules involved in crucial metabolic processes of all living cells, studies have focused on the expression of specific proteins produced by Leishmania and Trypanosoma by means of different biochemical, molecular and proteomic approaches in order to explore them as targets for understanding the parasite life cycle and developing new strategies against trypanosomiasis. With these proposals in mind, the book "Proteins and Proteome of Leishmania and Trypanosoma" encompasses (i) an integrated view about the biochemistry of parasites belonging to the Leishmania and Trypanosoma genera; (ii) an updated review on the expression of biologically relevant proteins by human pathogenic trypanosomatids and their possible role in the interaction with host cells/molecules as well as a target for development of both alternative chemotherapies and vaccine; and (iii) several pictures, diagrams and tables that can be used to illustrate both undergraduate and postgraduate teaching as well as scientific lectures, being a useful resource for students and researchers.
  • Energetics of peptide and protein binding to lipid membranes / William C. Wimley -- Membrane association and pore formation by alpha-helical peptides / Burkhard Bechinger -- Role of membrane lipids for the activity of pore forming peptides and proteins / Gustavo Fuertes ... [et al.] -- Cholesterol-dependent cytolysins / Robert J.C. Gilbert -- Laetiporus sulphureus lectin and aerolysin protein family / Jose Miguel Manchero .. [et al.] -- Interfacial interactions of pore-forming colicins / Helen Ridley, Christopher L. Johnson and Jeremy H. Lakey -- Permeabilization of the outer mitochondrial membrane by BCL-2 proteins / Ana J. Garcia-Suez ... [et al.] -- Molecular mechanism of sphingomyelin : specific membrane binding and pore formation by actinoporins / Biserka Bakra and Gregor Anderluh -- Hemolysin E (hlye, clya, shea) and related toxins / Stuart Hunt, Jeffrey Green and Peter J. Artymiuk -- Pore formation by cry toxins / Mario Soberin ... [et al.] -- Role of heparan sulfates and glycosphingolipids in the pore formation of basic polypeptides of cobra cardiotoxin / Wen-guey Wu ... [et al.] -- Amyloid peptide pores and the beta sheet conformation / Bruce L. Kagan and Jyothi Thundimadathil.
  • This book contains 14 original review chapters each yielding new, exciting and intriguing data about the emerging understanding of nucleolar structure and function in normal, stressed and diseased cells. The goal of this work is to provide special insight into the nucleolus of the past, present and future, as well its regulation, translocation, and biomedical function. A multitude of topics are introduced and discussed in detail, including nucleologenesis, nucleolar architecture, nucleolar targeting, retention, anchoring, translocation, and the relationship between the nucleolus and cancer.
  • Proteoglycan protocols Springer Protocols
  • pt. B ScienceDirect
    Pt. A. Mammalian blood coagulation factors and inhibitors -- Pt. B. Complement activation, fibrinolysis, and nonmammalian blood coagulation factors and inhibitors.
  • Proteomic and Metabolomic Approaches to Biomarker Discovery demonstrates how to leverage biomarkers to improve accuracy and reduce errors in research. Disease biomarker discovery is one of the most vibrant and important areas of research today, as the identification of reliable biomarkers has an enormous impact on disease diagnosis, selection of treatment regimens, and therapeutic monitoring. Various techniques are used in the biomarker discovery process, including techniques used in proteomics, the study of the proteins that make up an organism, and metabolomics, the study of chemical fingerprints created from cellular processes. Proteomic and Metabolomic Approaches to Biomarker Discovery is the only publication that covers techniques from both proteomics and metabolomics and includes all steps involved in biomarker discovery, from study design to study execution. The book describes methods, and presents a standard operating procedure for sample selection, preparation, and storage, as well as data analysis and modeling. This new standard effectively eliminates the differing methodologies used in studies and creates a unified approach. Readers will learn the advantages and disadvantages of the various techniques discussed, as well as potential difficulties inherent to all steps in the biomarker discovery process. A vital resource for biochemists, biologists, analytical chemists, bioanalytical chemists, clinical and medical technicians, researchers in pharmaceuticals, and graduate students, Proteomic and Metabolomic Approaches to Biomarker Discovery provides the information needed to reduce clinical error in the execution of research. Describes the use of biomarkers to reduce clinical errors in research. Includes techniques from a range of biomarker discoveries. Covers all steps involved in biomarker discovery, from study design to study execution.
  • This book is designed to help scientists without a strong background in analytical chemistry to understand basic analytical principles so they can apply them to proteomics profiling. It will also help researchers with an analytical chemistry background to break into the proteomics field. The title focuses on practical applications for proteomic research so readers are guided to design better experiments and to more easily interpret the resulting data. Bridges the gap between overly specialized courses and books in mass spectrometry, proteomics and analytical chemistryCovers the analytical consequences of protein and peptide modifications that may have a profound effect on how and what researchers actually measure; other books do not discuss such issuesIncludes real life examples illustrating the importance of problems in quantitation and validation of biomarkers from the perspective of analytical chemistry with additional references to other sources Helps in designing and executing proteomic experiments with sound analytics.
  • Proteomic characterization of the brain and cerebrospinal fluid of schizophrenia patients / Caf-Mendes, C.C.; Gattaz, W.F.; Schmitt, A.; Britto, L.R.G.; Martins-de-Souza, D -- Peripheral biomarker candidates in schizophrenia / Thome, J.; Bratek, A.; Krysta, K -- Schizophrenia : blood-serum-plasma metabolomics / Lista, S.; Giegling, I.; Rujescu, D -- Proteomic and metabolomic evidence for glial alterations in schizophrenia / Beasley, C.L.; Barakauskas, V.E -- Insights from proteomic studies on schizophrenia preclinical models : what can we learn for drug discovery? / Farrelly, L.A.; Fcking, M.; Cotter, D.R -- Metabolomics to study psychotic disorders and their metabolic comorbidities / Oresi, M -- Peripheral biomarkers for depression by plasma and serum proteomics / Domenici, E -- Proteomics of preclinical models of depression / Carboni, L -- Antidepressant response metabonomics / Qin, X.; Gao, X.; Qiao, Y.; Zhou, Y.; Tian, J.; Li, Z -- Proteomics and metabolomics of bipolar disorder / Sussulini, A -- Use of metabolomics and proteomics to reveal pathophysiological pathways in anxiety disorders / Altmaier, E.; Emeny, R.T.
  • Proteomics for the investigation of acute kidney injury / P. Devarajan -- Proteomics of plasma and urine in primary nephrotic syndrome in children / G. Candiano ... [et al.] -- Urinary proteome profiling to search for biomarkers in steroid-resistant nephrotic syndrome / A.Z. Traum, A.D. Schachter -- Searching for novel biomarkers and new therapeutic targets of diabetic nephropathy using proteomics approaches / V. Thongboonkerd -- Diagnostic and prognostic biomarkers in acute renal failure / J.M. Arthur ... [et al.] -- Proteomics and renal transplantation : searching for novel biomarkers and therapeutic targets / S. Schaub, J.A. Wilkins, P. Nickerson -- Metabolomics : a complementary tool in renal transplantation / D.S. Wishart -- Understanding and managing renal cell carcinoma : can proteomic studies contribute to clinical practice? -- R.A. Craven, R.E. Banks -- Capillary electrophoresis coupled to mass spectrometry for biomarker discovery and diagnosis of kidney diseases / P. Zürbig, H. Mischak -- Identification of urinary biomarkers by proteomics in newborns : use in obstructive nephropathy / S. Decramer ... [et al.] -- Proteomics and kidney stone disease / V. Thongboonkerd -- Exploring the uremic toxins using proteomic technologies / E. Schiffer -- Proteomic approaches for the study of cell signaling in the renal collecting duct / E.J. Hoorn -- Overview of kidney and urine proteome databases / Y. Yoshida ... [et al.].
  • Proteomic strategies for analyzing body fluids / Sung-Min Ahn and Richard J. Simpson -- Sample preparation of body fluids for proteomics analysis / Natalia Govorukhina and Rainer Bischoff -- Multiplexed immunoassays for protein profiling in human body fluids / Silke Wittemann ... [et al.] -- Deciphering the hieroglyphics of functional proteomics using small molecule probes / Wayne F. Patton -- Modification-specific proteomic analysis of glycoproteins in human body fluids by mass spectrometry / Jakob Bunkenborg, Per Hagglund, and Ole N. Jensen -- Plasma proteome database / Malabika Sarker, G. Hanumanthu, and Akhilesh Pandey -- 2D PAGE databases for proteins in human body fluids / Christine Hoogland ... [et al.] -- Bioinformatics and experimental design for biomarker discovery / Marc R. Wilkins and Sybille M.N. Hunt -- Integrative omics, pharmacoproteomics and human body fluids / K.K. Jain -- The human plasma and serum proteome / Gilbert S. Omenn ... [et al.] -- Proteomics of human urine / Visith Thongboonkerd ... [et al.] -- Proteomics of human cerebrospinal fluid / Margareta Ramström and Jonas Bergquist -- Proteomics of pleural effusion / Joost Hegmans, Annabrita Hemmes, and Bart Lambrecht -- Proteomics of bronchoalveolar lavage fluid and sputum / Ruddy Wattiez, Olivier Michel, and Paul Falmagne -- Proteomics of sinusitis nasal lavage fluid / Begona Casado, Simona Viglio, and James N. Baraniuk -- Proteomics of human saliva / Francisco M.L. Amado ... [et al.] -- Proteomics of human pancreatic juice / Mads Granborg, Anirban Maitra, and Akhilesh Pandey -- Proteomics of human bile / Troels Z. Kristiansen, Anirban Maitra, and Akhilesh Pandey -- Proteomics of amniotic fluid / David Crettaz ... [et al.] -- Proteomics of human milk / Amedeo Conti, Maria G. Giuffrida, and Maria Cavaletto -- Proteomics of nipple aspirate fluid in non-lactating women / Edward R. Sauter -- Proteomics of seminal fluid / Benjamin Solomon and Mark W. Duncan -- Proteomics of vitreous fluid / Atsushi Minamoto, Ken Yamane, and Tomoko Yokoyama -- Proteomics of human dialysate and ultrafiltrate fluids yielded by renal replacement therapy / Michael Walden ... [et al.].
  • Fulltext Springer Protocols
  • The misfolding and aggregation of specific proteins is an early and obligatory event in many of the age-related neurodegenerative diseases of humans, and appears to occur many years before the onset of clinical symptoms. The initial cause of this pathogenic cascade and the means whereby disease spreads through the nervous system, remain uncertain. A recent surge of research, first instigated by pathologic similarities between prion disease and Alzheimer's disease, has increasingly implicated corruptive protein templating, or seeding, as a prime factor in the neurodegenerative process. The prion-like corruption of proteins also characterizes such clinically and etiologically diverse neurological disorders as Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, and frontotemporal lobar degeneration. Understanding the misfolding, aggregation, trafficking and pathogenicity of affected proteins thus could reveal universal principles and common therapeutic targets for some of the most devastating and intractable human brain disorders.
  • Print Material
    Alcohol / Robert J. Sokol and Beth Nordstrom Bailey -- Developmental toxicology and teratology / James W. Hanson and Jan M. Friedman -- Occupational hazards / George R. Saade -- Smoking / Jorge E. Tolosa and Surasith Chaithongwongwatthana -- Ionizing radiation / Robert L. Brent -- Microwaves and ultrasound / Robert L. Brent -- Exercise - risks and benefits / James Clapp -- Routine antenatal laboratory tests and specific screening tests / Calvin J. Hobel -- Assessment of gestational age / Lawrence D. Platt -- Second trimester biochemical screening for neural tube defects and aneuploidy / John C. Hobbins -- Sonographic and first trimester detection of aneuploidy / Fergal D. Malone -- Indices of maturity / Alessandro Ghidini and Anna Locatelli -- Clinical use of doppler / Henry L. Galan -- Fetal echocardiography / Joshua A. Copel and Charles S. Kleinman -- Fetal biophysical profile / Michael P. Nageotte -- Chorionic villus sampling / Ronald J. Wapner -- Genetic amniocentesis / Katharine D. Wenstrom -- Third trimester amniocentesis / Nancy Chescheir -- Chronic hypertension / Baha M. Sibai -- Immunizations / Stanley A. Gall -- Cytomegalovirus / Hans M. L. Spiegel and John L. Sever -- Herpes simplex / Jeanne S. Sheffield -- Influenza / Jeanne S. Sheffield -- West Nile virus / Ronald Gibbs and Joel K. Schwartz -- Human immune deficiency virus infection / Howard Minkoff -- Parvovirus B19 infection / Maureen P. Malee -- Syphilis / Vanessa Laibl and George D. Wendel, Jr -- Rubella / Hans M. L. Spiegel and John L. Sever -- Group B streptococcus / Mara J. Dinsmoor -- Toxoplasmosis / Shad Deering -- Varicella / Hans M. L. Spiegel and John L. Sever -- Tuberculosis / Kim A. Boggess -- Urinary tract infections / F. Gary Cunningham -- Acute abdominal pain resulting from non-obstetric causes / Sara Sukalich and Fred M. Howard -- Acute pancreatitis / Sarah H. Poggi -- Gallbladder / Monica Longo and Gary D. V. Hankins -- Mastitis / Wendy F. Hansen, Deborah Hubbard, and Jennifer R. Niebyl -- First trimester vaginal bleeding / Marsha Wheeler -- Cervical incompetence / Wendy F. Hansen -- Fetal blood sampling / Alessandro Ghidini and Anna Locatelli -- Fetal reduction / Mark I. Evans -- Intrauterine transfusion / Frederick U. Eruo and Raymond Bahado-Singh -- External cephalic version / Monica Longo and Gary D. V. Hankins -- Induction of labour / Anna M. McKeown and Michael P. Nageotte -- Amnioinfusion : indications and techniques / Catherine Y. Spong -- Sickle cell disease / Chad K. Klauser and John C. Morrison -- Isoimmune thrombocytopenia / Jane Cleary-Goldman and Mary E. D'Alton -- Autoimmune disease / Charles J. Lockwood and Edmund F. Funai -- Cardiac disease / Katharine D. Wenstrom -- Peripartum cardiomyopathy / F. Gary Cunningham -- Thromboembolism / Alan Peaceman -- Renal disease / Linda Fonseca, Larry C. Gilstrap III and Susan Ramin -- Obesity / Frank J. Zlatnik -- Gestational diabetes / Donald R. Coustan -- Diabetes mellitus / Steven G. Gabbe -- Hypothyroidism / Brian Casey -- Hyperthyroidism / George D. Wendel, Jr -- Acute and chronic hepatitis / Marshall W. Carpenter -- Asthma / Michael Schatz -- Epilepsy / Neil K. Kochenour --
  • Establishment of adventitious root cultures of Echinacea purpurea for the production of caffeic acid derivatives / K.Y. Paek, H.N. Murthy and E.J. Hahn -- In vitro propagation of Rauwolfia serpentina using liquid medium, assessment of genetic fidelity of micropropagated plants, and simultaneous quantitation of reserpine, ajmaline, and ajmalicine / M.K. Goel ... [et al.] -- Medicinal properties, in vitro protocols and secondary metabolite analyses of Scots pine / H. Haggman ... [et al.] -- Saussurea medusa cell suspension cultures for flavonoid production / C.Z. Liu and P.K. Saxena -- Large-scale in vitro multiplication of Crataeva nurvala / S.B. Babbar, N. Walia and A. Kaur -- Bilberry in vitro protocols and analyses of phenolic compounds / L. Jaakola ... [et al.] -- In vitro propagation of two tuberous medicinal plants: Holostemma ada-kodien and Ipomoea mauritiana / S.P. Geetha ... [et al.] -- In vitro production of gymnemic acid from Gymnema sylvestre (Retz) R. Br. Ex Roemer and Schultes through callus culture under abiotic stress conditions / A.B. Ali Ahmed, A.S. Rao and M.V. Rao -- Establishment of plant regeneration and cryopreservation system from zygotic embryo-derived embryogenic cell suspension cultures of Ranunculus kazusensis / S.W. Kim and M.J. Oh -- In vitro culture and secondary metabolite isolation in bryophytes / A. Sabovljevic, M. Sabovljevic and N. Jockovic -- Micropropagation and in vitro conservation of vanilla (Vanilla planifolia Andrews) / M. Divakaran and K.N. Babu -- Protocol for in vitro regeneration and marker glycoside assessment in Swertia chirata Buch-Ham / S. Koul ... [et al.] -- Protocols for establishment of an in vitro collection of medicinal plants in the genus Scutellaria / I.B. Cole, F.T. Farooq and S.J. Murch -- Protocols for in vitro culture and phytochemical analysis of Phyllanthus species (Euphorbiaceae) / E. Catapan ... [et al.] -- In vitro clonal propagation of Asparagus racemosus, a high value medicinal plant / S. Saxena and N. Bopana -- Micropropagation of Penthorum chinense through axillary buds / J. Yang and Z.S. Peng -- Spontaneous plant regeneration and production of secondary metabolites from hairy root cultures of Centaurium erythraea Rafn / A. Subotic ... [et al.] -- Transgenic Hypericum perforatum / G. Franklin, M.M. Oliveira and A.C. Dias -- Agrobacterium-mediated transformation of Ruta graveolens L / K. Lievre ... [et al.] -- Gene expression profiling in Taxus baccata L. seedlings and cell cultures / K. Brun akova and J. Kosuth -- Catapol production in Chinese foxglove (Rehmannia glutinosa Libos.) hairy roots transformed with Agrobacterium rhizogenes ATCC15834 / S.J. Hwang -- Identification of medicinal plants and plant sequences: multiplexed MLPA assay / R.A. Barthelson -- Isolation of microsatellites from Catharanthus roseus (L.) G. Don using enriched libraries / S. Bhatia and B. Shokeen -- Production of cinnamyl glycosides in compact callus aggregate cultures of Rhodiola rosea through biotransformation of cinnamyl alcohol / Z. Gyorgy and A. Hohtola -- Spearmint plantlet culture system as a means to study secondary metabolism / B. Tisserat, M. Berhow and S.F. Vaughn -- Bioreactor production of secondary metabolites from cell cultures of periwinkle and sandalwood / J.V. Valluri -- Camptothecin production by in vitro cultures and plant regeneration in Ophiorrhiza species / T. Asano ... [et al.] -- Metabolomic analysis of Ocotea odorifera cell cultures: a model protocol for acquiring metabolite data / M. Maraschin ... [et al.] -- Production of 9-methoxycanthin-6-one from callus cultures of (Eurycoma longifolia Jack) Tongkat Ali / M. Maziah and N. Rosli -- Plant secondary metabolism in altered gravity / L.K. Tuominen, L.H. Levine and M.E. Musgrave -- The role of biotechnology in the production of the anticancer compound podophyllotoxin / H. Lata, C.S. Mizuno and R.M. Moraes.
  • Neurosphere and Neural Colony-Forming Cell Assays / Sharon A. Louis, Brent A. Reynolds -- Directed Neuronal Differentiation of Embryonic and Adult-Derived Neurosphere Cells / Marcos R. Costa, Ravi Jagasia, Benedikt Berninger -- Culture and Differentiation of Human Neural Stem Cells / Soojung Shin, Mohan Vemuri -- Neural Differentiation of Human Embryonic Stem Cells / Mirella Dottori, Alice Pébay, Martin F. Pera -- Isolation and Culture of Primary Human CNS Neural Cells / Manon Blain, Veronique E. Miron, Caroline Lambert, Peter J. Darlington, Qiao-Ling Cui, Philippe Saikali, V. Wee Yong, Jack P. Antel -- Bioengineering Protocols for Neural Precursor Cell Expansion / Behnam A. Baghbaderani, Arindom Sen, Michael S. Kallos, Leo A. Behie -- Intracellular Calcium Assays in Dissociated Primary Cortical Neurons / Navjot Kaur, David V. Thompson, David Judd, David R. Piper, Richard G. Del Mastro -- Dissociated Hippocampal Cultures / Francine Nault, Paul Koninck -- Primary Sensory and Motor Neuron Cultures / Andrea M. Vincent, Eva L. Feldman -- Retinal Cell and Tissue Culture / Francisco L.A.F. Gomes, Michel Cayouette -- Preparation of Normal and Reactive Astrocyte Cultures / Jean Vellis, Cristina A. Ghiani, Ina B. Wanner, Ruth Cole -- Oligodendrocyte Progenitor Cell Culture / Akiko Nishiyama, Ryusuke Suzuki, Hao Zuo, Xiaoqin Zhu -- Isolation of Microglia Subpopulations / Makoto Sawada, Hiromi Suzuki -- Microglia from Progenitor Cells in Mouse Neopallium / Sergey Fedoroff, Arleen Richardson -- Primary Schwann Cell Cultures / Haesun A. Kim, Patrice Maurel -- Primary Dissociated Astrocyte and Neuron Co-culture / Shelley Jacobs, Laurie C. Doering -- Cerebellar Slice Cultures / Josef P. Kapfhammer -- Hippocampal Slice Cultures / Jesse E. Hanson, Adrienne L. Orr, Silvia Fernandez-Illescas, Ricardo A. Valenzuela, Daniel V. Madison -- Molecular Substrates for Growing Neurons in Culture / Saulius Satkauskas, Arnaud Muller, Morgane Roth, Dominique Bagnard -- Guidance and Outgrowth Assays for Embryonic Thalamic Axons / Alexandre Bonnin -- Detection of Cell Death in Neuronal Cultures / Sean P. Cregan -- Live Imaging of Neural Cell Functions / Sabine Bavamian, Eliana Scemes, Paolo Meda -- Tissue Culture Procedures and Tips / Arleen Richardson, Sergey Fedoroff.
  • Genomic DNA isolation from different biological materials / Duckchul Park -- Extraction of plant RNA / Elspeth MacRae -- Overview on hybridization and detection techniques / Elena Hilario -- Checkerboard DNA/DNA hybridization technology : using DIG detection / Lisa S. Gellen, Glenn Wall-Manning, and Chris H. Sissons -- Nonradioactive northern and southern analyses from plant samples / Christoph Peterhaensel, Dagmar Weier, and Thomas Lahaye -- Screening a BAC library with nonradioactive overlapping oligonucleotide (overgo) probes / Elena Hilario, Tiffany F. Bennell, and Erik Rikkerink -- Direct in-gel hybridization of DNA with digoxigenin-labeled probes / Saeed A. Khan and Mohamed S. Nawaz -- In situ hybridization of termite microbes / Shigeharu Moriya ... [et al.] -- RNA electrophoretic mobility shift assay using a fluorescent DNA sequencer / Yukinori Eguchi -- Comparative quantitation of mRNA expression in the central nervous system using fluorescence in situ hybridization / Darren J. Day, Eli M. Mrkusich, and John H. Miller -- Visualization of gene expression by fluorescent multiplex real-time PCR amplification / Maria Rosa Ponce ... [et al.] -- Fluorescence in situ hybridization for the identification of environmental microbes / Annelie Pernthaler and Jakob Pernthaler -- Introduction to kinetic (real-time) PCR / John Mackay -- Validation of siRNA knockdowns by quantitative real-time PCR / Sukru Tuzmen -- Real-time quantitative PCR as an alternative to southern blot or fluorescence in situ hybridization for detection -- Of gene-copy number changes / Jasmien Hoebeeck, Frank Speleman, and Jo Vandesompele -- Design and work-up of a new molecular diagnostic assay based on real-time PCR / Harald Kessler -- Real-time PCR fluorescent chemistries / John Mackay and Olfert Landt -- Microarrays : an overview / Norman H. Lee and Alexander I. Saeed -- Oligonucleotide microarrays for the study of coastal microbial communities / Gaspar Taroncher-Oldenburg and Bess B. Ward.
  • "Preface: This book aims at providing a comprehensive and practical guide to proton and carbon ion therapy for a broad range of personnel in medical physics and radiation therapy, including medical physicists, radiation oncologists, dosimetrists, therapists, medical engineers, and trainees in these disciplines. The scope of this book includes physics and radiobiology basics of proton and ion beams, dosimetry methods and radiation measurements, treatment delivery systems, and practical guidance on patient setup, target localization, and treatment planning for clinical proton and carbon ion therapy, as well as detailed reports on the treatment of pediatric cancers, lymphomas, and various other cancers. The aim is to offer a balanced and critical assessment of the state-of-the-art proton and carbon ion therapy along with the discussion of major challenges and future outlook. This book contains 11 chapters. The first chapter provides an overview, and the final chapter describes future challenges. The remaining content is divided into three sections. The first section provides the basic aspects of proton and carbon ion therapy equipment covering accelerators, gantries, and delivery systems. Chapter 2 describes accelerators for proton and carbon ion therapy, including cyclotron, synchrotron, and other acceleration developments (such as dielectric wall accelerator, laser accelerated particle beams, and new concepts, including the cyclinac and compact cyclotron solutions). Chapter 3 describes proton and carbon ion therapy systems, with a focus on their major components, including energy selection systems, beam transport systems, control systems, gantries, and beam delivery systems"--Provided by publisher.
  • While radiation therapy is a mainstay of cancer treatment, traditional linear accelerators mainly use photons to irradiate cancerous tissue. Photons deposit much more energy in the surrounding normal tissue than protons. Proton beam therapy is a revolutionary alternative that deposits most of its cancer-killing energy within the area of the tumor, thereby potentially improving cure rates and reducing side effects in properly selected patients. This book guides the reader through existing evidence supporting proton beam therapy for an increasing number of patients and conditions, including pediatric, prostate, and lung cancer, mediastinal tumors, skull base tumors, conditions of the eye, and sarcomas.
  • Discovery and Development of Proton Pump Inhibitors / Satoh, H. (Kyoto) -- Pharmacokinetics, Pharmacodynamics, and Pharmacogenetics of Proton Pump Inhibitors / Furuta, T.; Sugimoto, M.; Shirai, N. (Hamamatsu) -- Proton Pump Inhibitors in Gastroesophageal Reflux Disease / Bruley des Varannes, S. (Nantes) -- Proton Pump Inhibitors in Gastroprotection: Prevention and Healing of Nonsteroidal Anti-Inflammatory Drug-, Aspirin-, and Cyclooxygenase-2 Inhibitor-Induced Gastroduodenal Lesions / Kyaw, M.H.; Chan, F.K.L. (Hong Kong) -- Proton Pump Inhibitors: Key Ingredients in Helicobacter pylori Eradication Treatment / Sugiyama, T. (Toyama City) -- Proton Pump Inhibitor Management in Bleeding Peptic Ulcer Disease / Sung, J. (Hong Kong) -- Proton Pump Inhibitors in Functional Dyspepsia / Miwa, H. (Nishinomiya) -- Role of Acid Suppression in Exocrine Pancreatic Insufficiency: A Therapeutic Principle / Waldthaler, A.; Schütte, K.; Malfertheiner, P. (Magdeburg) -- Proton Pump Inhibitors and Gastrointestinal Side Effects / Nakamura, S. (Fukuoka); Seno, H.; Chiba, T. (Kyoto) -- Administration of Proton Pump Inhibitors and Risk of Systemic Side Effects / Kinoshita, Y.; Ishihara, S. (Izumo).
  • Proton therapy physics 2012, CRCnetBASE
    "Compared to x-ray-based radiotherapeutic modalities, proton therapy provides greater 3D localization, higher beam doses, access to deeper tumors, and less damage to surrounding healthy tissue. Though over fifty years old, it is now coming to the forefront of cancer treatment with greater understanding of the biophysics and better treatment and patient outcomes. This text presents an overview of proton therapy that addresses all key topics including, biophysics, accelerators, hardware, beam delivery, treatment planning, dose calculation, quality assurance, and precision. Features (1) Provides an overview of proton therapy; (2) Covers beam delivery using passive scattering and magnetic beam scanning; (3) Details the physics of treatment planning for homogenous fields and intensity-modulated fields; and (4) Discusses precision and uncertainties for both moving and non-moving targets"--Provided by publisher.
  • Proximal Humerus Fractures includes everything the orthopedic surgeon needs to know about the clinical management of these common shoulder injuries. Although non-operative treatment techniques are addressed and can be used in less severe circumstances, this book focuses mainly on the current operative treatment techniques for proximal humerus and tuberosity fractures, malunions and nonunions, including open reduction, percutaneous pinning, locking plate and intramedullary nail fixation, and humeral head hemiarthroplasty and reverse shoulder arthroplasty. A chapter on complications associated with these types of fractures and their management is also included. Dedicated to a common musculoskeletal injury, especially in athletes and the elderly suffering from osteoporosis, Proximal Humerus Fractures will be a valuable resource to all orthopedic surgeons and practitioners of sports medicine.
  • Pruritus 2010, Springer
    Part 1. Neurophysiology -- Neuroanatomy of Itch / Akihiko Ikoma -- Neuroreceptors and Neuromediators / Sonja Ständer and Thomas A. Luger -- The Brain in the Skin: Neuro-Epidermal Synapses / Nicholas Boulais and Laurent Misery -- Central Transmission: From Skin to Brain / Tejesh Surendra Patel and Gil Yosipovitch -- Modulation of Pruritus: Peripheral and Central Sensitisation / Martin Schmelz -- Interaction of Pruritus and Pain / Martin Schmelz -- Neuroimaging / Florian Pfab, Michael Valet, Thomas Tölle, Heidrun Behrendt and Johannes Ring, et al. -- Measurement of Itch / Joanna Wallengren -- Experimental Models of Itch / Ulysse Pereira and Laurent Misery -- Part 2. Clinics -- Pruritus, Pain and Other Abnormal Skin Sensations / Laurent Misery -- The Epidemiology of Pruritus / Florence Dalgard and Elke Weisshaar -- Classification / Sonja Ständer -- Examination of Patients / Elke Weisshaar -- Inflammatory Diseases / Jacek C. Szepietowski and Adam Reich -- Pruritus in Autoimmune Diseases / Yozo Ishiuji and Alan B. Fleischer -- Urticaria / Ulrike Raap, Alexander Kapp and Bettina Wedi -- Pruritic Skin Diseases in Travellers / Eric Caumes -- Pruritus in Cutaneous T-cell Lymphoma / Tobias Görge and Meinhard Schiller -- Anal Pruritus / Sylvia Proske and Wolfgang Hartschuh -- Secondary Reactive Conditions in Pruritic Skin / Joanna Wallengren -- Aquadynia and Aquagenic Pruritus / Laurent Misery -- Sensitive Skin / Laurent Misery and Sonja Ständer -- Neurogenic Pruritus with Cerebral and/or Medullary Abnormalities / Camille Fleuret and Laurent Misery -- Localized Neuropathic Pruritus / Martin Marziniak, Esther Pogatzki-Zahn and Stefan Evers -- Brachioradial Pruritus / Martin Marziniak and Sonja Ständer -- Other Neurological Causes of Itch / Martin Marziniak, Esther Pogatzki-Zahn and Stefan Evers -- Chronic Kidney Disease-Associated Pruritus / Thomas Mettang -- Pruritus in Patients with Hepatobiliary Diseases / Andreas E. Kremer, Ronald P. J. Oude-Elferink and Ulrich Beuers -- Endocrine Diseases / Elke Weisshaar -- Pruritus in the Course of Malignancy / Zbigniew Zylicz and Malgorzata Krajnik -- Drugs / Jacek C. Szepietowski and Adam Reich -- Interaction Between Pruritus and Stress or Other Psychosomatic Factors / Laurent Misery -- Psychosomatic Aspects and Psychiatric Conditions / Gudrun Schneider -- Psychosomatics and Psychiatry, Psychological Approach / Sabine Dutray and Laurent Misery -- Psychogenic Pruritus / Laurent Misery -- Pruritus in Children / Matthieu Gréco and Laurent Misery -- Pruritus Vulvae / Micheline Moyal-Barracco -- Part 3. Treatment -- General Principles and Guidelines / Elke Weisshaar -- Menthol / Laurent Misery and Sonja Ständer -- Capsaicin / Laurent Misery -- Topical Immunomodulators / Laurent Misery -- Cannabinoid-Receptor Agonists / Sonja Ständer -- Other Topical Treatments / Laurent Misery -- Antihistamines / Caroline Gaudy-Marqueste -- Anticonvulsants for the Treatment of Pruritus / Nora V. Bergasa and Deewan Deewan -- Opioid Receptor Antagonists or Agonists / Laurent Misery -- Serotonin Reuptake Inhibitors and Other Antidepressants in the Treatment of Chronic Pruritus / Zbigniew Zylicz and Małgorzata Krajnik -- Systemic Immunosuppressants in the Treatment of Pruritus / Silvia Moretti, Francesca Prignano and Torello Lotti -- Other Systemic Treatments / Sonja Ständer -- Psychological Intervention / Sabine Dutray and Laurent Misery -- Ultraviolet Phototherapy of Pruritus / Joanna Wallengren -- Itch and Acupuncture / Laurent Misery and Laurence Potin-Richard -- Future Perspectives: Outlook / Sonja Ständer and Laurent Misery.
  • Part I. Regulation and Control of Virulence -- 1. Small RNAs of Pseudomonas spp. / Elisabeth Sonnleitner, Nicolas González and Dieter Haas -- 2. 2-Alkyl-4(1H)-Quinolone Signalling in Pseudomonas aeruginosa / Matthew P. Fletcher, Stephan Heeb, Siri Ram Chhabra, Stephen P. Diggle, Paul Williams, and Miguel Cámara -- 3. Cell-Surface Signalling in Pseudomonas / María A. Llamas and Wilbert Bitter -- 4. Second Messenger c-di-GMP Signaling in Pseudomonas aeruginosa / Massimo Merighi and Steve Lory -- Part II. Life Styles -- 5. Emergence of Pseudomonas aeruginosa in Cystic Fibrosis Lung Infections / Joanna B. Goldberg -- 6. Insights into the Life Styles of Pseudomonas stutzeri / Elena García-Valdés, Magdalena Mulet, and Jorge Lalucat -- Part III. Physiology, Metabolism and Markers -- 7. Pyoverdine Siderophores as Taxonomic and Phylogenic Markers / Jean-Marie Meyer -- 8. Metabolism of Acyclic Terpenes by Pseudomonas / Jesús Campos-García -- 9. Heavy Metal Resistance in Pseudomonads / Esther Aguilar-Barajas, Martha I. Ramírez-Díaz, Héctor Riveros-Rosas, and Carlos Cervantes.
  • This new companion to Hochberg et al.'s Rheumatology focuses on the momentous recent advances in our understanding of the genetics and immunology of psoriatic and reactive arthritis, and their implications for diagnosis and management. Leading international authorities explore new concepts in genetic and pathogenic mechanisms and early diagnosis; provide comprehensive, well-illustrated coverage of clinical features; evaluate the very latest therapeutic options, including biologics; and discuss clinical outcome measures.
  • Epidemiology / Margarita Alegría ... [et al.] -- Virology, immunology, transmission, and disease stage / Karl Goodkin -- Medical treatment and occupational exposure / Ellen A.B. Morrison, Jon A. Levenso -- Psychiatric assessment / María Fernanda Gómez, Mary Alice O'Dowd -- Psychological and neuropsychological testing / Joel K. Levy -- Electrophysiology and brain mapping / Harold W. Goforth, Lukasz M. Konopka -- Psychological reactions / Vicenzio Holder-Perkins, Jeffrey S. Akman -- Stress-distress spectrum and adjustment disorders / Dimitri D. Markov, Elisabeth J.S. Kunkel, Howard Field -- Anxiety disorders / Annette M. Matthews, Manuel Trujillo -- Mood disorders / Pedro Ruiz -- Personality disorders / Khenu Singh, Herb Ochitill -- Cognitive disorders / Angela M. McBride, Francisco Fernandez -- Psychotic disorders / Ewald Horwath, Francine Cournos -- Substance use disorders / Stephen J. Ferrando, Steven L. Batki -- Sleep disorders / Carlos A. Santana, Francisco Fernandez -- Psychotropic drug interactions with antiretroviral medications / Philip A. Bialer, Kyle S. Kato, Vassilios Latoussakis -- Pain syndromes / William Breitbart -- Sexually transmitted infections / Angela L. Stotts ... [et al.] -- Psychiatric comorbidities in medically ill patients with HIV/AIDS / Stephen J. Ferrando, Constantine G. Lyketsos -- HIV/AIDS among Hispanic Americans / Pedro Ruiz, Frank Fernandez -- HIV/AIDS among African Americans / William B. Lawson, Janice G. Hutchinson, Dianne L. Reynolds -- HIV/AIDS among Asian and Pacific Islander Americans / Lynette J. Menezes, Todd Wills, Karina D'Souza -- HIV/AIDS among American Indians and Alaska natives / Carol E. Kaufman ... [et al.] -- HIV/AIDS among neonates and infant / Andrea Stolar, Johanna Goldfarb -- HIV/AIDS among children and adolescents / Andres J. Pumariega, Margaret A. Shugart, JoAnne B. Pumariega -- HIV/AIDS among older adults / Maria D. Llorente, Julie E. Malphurs -- HIV/AIDS among women / Isabel T. Lagomasino, Gustavo Rodriguez -- HIV/AIDS among men who have sex with men / Milton L. Wainberg, Kenneth B. Ashley -- HIV/AIDS among women who have sex with women / Alison R. Jones, Cynthia L. Hoyler -- HIV/AIDS among the homeless / Jacqueline Maus Feldman, Stephen M. Goldfinger -- HIV/AIDS among prisoners / Wade C. Myers ... [et al.] -- HIV/AIDS and the patient's family / James L. Griffith, Michael Golder -- Ethical, forensic, and legal considerations / James Satriano -- Religious and spiritual considerations / Daniel W. Hicks, Francis G. Lu -- Psychotherapeutic strategies / Claire Zilber -- Complementary and holistic medicine / Janet Konefal, Jessica Lillisand -- Biopsychosocial aspects / Cheryl Gore-Felton, Cheryl Koopman, David Spiegel -- Suicide and end-of-life care / Mary Ann Cohen -- Prevention and education strategies / Michael D. Knox, Tiffany Chenneville -- Physician assisted suicide and voluntary euthanasia / Marshall Forstein.
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    Bipolar disorder: special issues in pregnancy and the postpartum / Lori L. Altshuler and Carol Kiriakos -- Schizophrenia during pregnancy and the postpartum period / Mary V. Seeman -- Pregnancy and substance abuse / Karen A. Miotto ... [et al.] -- Eating disorders in pregnancy and the postpartum: empirically informed treatment guidelines / Debra L. Franko -- Children of parents with mental illness: outcomes and interventions / Mary F. Brunette and Teresa Jacobsen. General considerations in treating psychiatric disorders during pregnancy and following delivery / Victoria Hendrick -- Prevalence, clinical course, and management of depression during pregnancy / Sanjog Kalra and Adrienne Einarson -- Postpartum depression: a common complication of childbirth / C. Neill Epperson and Jennifer Ballew -- Treatment of anxiety disorders in pregnancy and the postpartum / Jonathan S. Abramowitz, Karin Larsen, and Katherine M. Moore --
  • This book offers a comprehensive survey of the current state of knowledge in the field of neuro-psychopharmacology in childhood and adolescence. In the first part, the essentials of neuro-psychopharmacology are presented in order to provide a deeper understanding of the principles and particularities in the pharmacotherapy of children and adolescents. This part includes information on neurotransmitters and signal transduction pathways, molecular brain structures as targets for psychiatric drugs, characteristics of psychopharmacological therapy in children and adolescents, ontogenetic influences on pharmacokinetics and pharmacodynamics, and pharmacotherapy in the outpatient setting. The part on classes of psychiatric medications, which covers antidepressants, antipsychotics, anxiolytics and sedative-hypnotics, mood stabilizers, and psychostimulants and other drugs used in the treatment of attention-deficit/hyperactivity disorder, provides sufficient background material to better understand how psychoactive drugs work, and why, when, and for whom they should be used. For each drug within a class, information on its mechanisms of action, clinical pharmacology, indications, dosages, and cognate issues are reviewed. In the third part, the disorder-specific and symptom-oriented medication is described and discerningly evaluated from a practical point of view, providing physicians with precise instructions on how to proceed. Psychiatric Drugs in Children and Adolescents includes numerous tables, figures and illustrations and offers a valuable reference work for child and adolescent psychiatrists and psychotherapists, pediatricians, general practitioners, psychologists, and nursing staff, as well as teachers.
  • Psychiatric ethics /. 4th ed. Lane Catalog record
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  • Psychiatric genetics. 1st ed. Lane Catalog record
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    Questions, models, and methods in psychiatric genetics / Lindon Eaves ... [et al.] -- Genetics of schizophrenia: linkage and association studies / Brien Riley and Kenneth S. Kendler -- Genetics of anxiety disorders / John M. Hettema -- Genetics of substance use disorders / Carol A. Prescott, Hermine H. Maes, and Kenneth S. Kendler -- Genetic influence on the development of antisocial behavior / Kristen C. Jacobson.
  • I. General principles of effective interviewing -- II. The psychiatric history -- III. Interviewing for diagnosis, the psychiatric review of symptoms -- IV. Interviewing for treatment -- Appendixes -- References -- Index.
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    Nursing process -- Anxiety and related disorders -- Mood disorders -- Schizophrenia and other psychotic disorders -- Adjustment disorders -- Personality disorders -- Disorders of infancy, childhood, and adolescence -- Cognitive disorders : delirium, dementia, and amnestic disorders -- Substance-related disorders -- Eating disorders -- Sexual and gender identity disorders -- Appendixes: Suicide assessement and intervention guidelines ; Crisis and crisis intervention ; Client rights ; Guidelines for seclusion and restraint based on JCAHO standards ; Grief and loss : caregivers, clients, and families ; Spirituality as a dimension of the person ; Psychiatric and psychosocial therapies ; Psychopharmacology ; Comparison of developmental theories ; Defense mechanisms and strategies ; Standards of care for psychiatric - mental health nursing practice ; DSM-IV-TR classification.
  • Psychiatry at a glance. 3rd ed. Lane Catalog record
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    Child psychiatry I -- Child psychiatry II -- The psychiatry of adolescence -- Learning disability (mental retardation) -- Consultation-liaison psychiatry -- Psychiatry in the community -- Forensic psychiatry -- The 1983 mental health act (MHA) -- Risk assessment and management in psychiatry -- Psychosexual disorders -- Psychiatric aspects of HIV and AIDS -- Psychological treatments -- Physical treatments I -- Physical treatments II -- Cross-cultural psychiatry -- Unusual psychiatric syndromes -- Preparing for clinical examinations in psychiatry. The psychiatric history and mental state examination (MSE) -- Diagnosis and classification in psychiatry -- Schizophrenia : phenomenology and aetiology -- Schizophrenia : management and prognosis -- Depression -- Bipolar affective disorder (including mania) -- Suicide and deliberate self-harm (DSH) -- Stress reactions (including bereavement) -- Anxiety disorders -- Obsessions and compulsions -- Eating disorders -- Disorders of personality -- Substance misuse -- Alcohol abuse and dependence -- Disorders of female reproductive life -- Functional disorders in old age -- Acute confusional states (delirium) -- The dementias -- Neuropsychiatry I -- Neuropsychiatry II --
  • Psychiatry at a glance. 4th ed. Lane Catalog record
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    Interview techniques and history-taking -- Examination of the mental state -- Risk assessments -- Syndromes and diagnosis -- Aetiology -- Investigations -- Treatment -- Prognosis -- Formulation -- Psychiatric aspects of physical disease -- Organic brain syndromes -- Schizophrenia and delusional disorders -- Bipolar disorders -- Internalizing disorders 1 : depression, anxiety and the fear disorders -- Internalizing disorders 2 : somatic presentations of emotional distress -- Externalizing disorders : misuse of alcohol and drugs, and eating disorders -- Personality disorders -- Disorders of early life : learning disability -- Childhood and adolescence -- Sexual and reproductive disorders -- Disorders of older people -- Services for people with mental health problems -- Ethical dilemmas and legal aspects.
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  • Epidemiology of psychiatric symptoms in Parkinson's Disease -- Depression, apathy and anxiety disorders -- Apathy in Parkinson's Disease -- Disorders of visual perception in Parkinson's Disease and other Lewy body disorders -- Psychosis and Parkinson's Disease -- Sleep in Parkinson's Disease and dementia with Lewy bodies -- Sexual problems in Parkinson's Disease -- An update on impulse control disorders in Parkinson's Disease -- Neuropsychological features of early cognitive impairment in Parkinson's Disease -- Parkinson's Disease with dementia -- Somatoform disorders in Parkinson's Disease and dementia with Lewy bodies evidence underlying psychotic traits -- Drug-induced Parkinsonism and abnormal involuntary movements.
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    Psychotherapy and the single synapse -- A new intellectual framework for psychiatry -- Biology and the future of psychoanalysis -- From metapsychology to molecular biology -- Neurobiology and molecular biology -- Neural science -- The molecular biology of memory storage -- Genes, brains and self-understanding.
  • Psychiatry. 2nd ed. Lane Catalog record
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  • Psychiatry. 2nd ed. Lane Catalog record
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    Psychiatric assessment and treatment planning / Janis L. Cutler -- The psychiatric interview / Lyle Rosnick -- Mood disorders / Leo Sher, David A. Kahn, and Maria A. Oquendo -- Schizophrenia and other psychotic disorders / Thomas Smith, Ewald Horwath, and Francine Cournos -- Cognitive disorders and mental disorders due to general medical conditions / Jennifer M. Rucci and Robert E. Feinstein -- Anxiety disorders / Franklin R. Schneier ... [et al.] -- Alcohol and substance use disorders / Benjamin R. Bryan and Frances R. Levin -- Personality disorders / Eve Caligor, Frank Yeomans, and Ze'ev Levin -- Eating disorders / Michael J. Devlin and Joanna E. Steinglass -- Somatoform and factitious disorders / Kelli Jane K. Harding and Steven E. Hyler -- Suicide and violence / Cheryl A. Chessick and Robert E. Feinstein -- Psychological factors affecting medical conditions / Lucy A. Epstein and Eve Caligor -- Child, adolescent, and adult development / Jonathan A. Slater, Katharine A. Stratigos, and Janis L. Cutler -- Child and adolescent psychiatry / Daniel T. Chrzanowski ... [et al.] -- Psychotherapy / David D. Olds and Fredric N. Busch -- Pharmacotherapy and electroconvulsive therapy / Jonathan W. Stewart, L. Mark Russakoff, and Jessica Ann Stewart.
  • Psychiatry. 3rd ed. Lane Catalog record
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    Signs, symptoms, and diagnosis -- Assessment -- Aetiology and the scientific basis of psychiatry -- Personality and its disorders -- Reactions to stressful experiences -- Anxiety and obsessional disorders -- Physical symptoms not explained by organic pathology -- Mood disorders -- Schizophrenia and related disorders -- Delirium, dementia, and other cognitive disorders -- Psychiatry and medicine -- -- Eating and sleep disorders -- Suicide and deliberate self-harm -- Problems due to the use of alcohol and other psychoactive substances -- Problems of sexuality and gender -- Psychiatry of the elderly -- Drugs and other physical treatments -- Psychological treatment -- Mental health care for the community -- Child and adolescent psychiatry -- Learning disability -- Psychiatry and the law.
  • Psychiatry. 5th ed. Lane Catalog record
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    The clinical examination -- Personality disorders -- Psychotic disorders -- Mood disorders -- Anxiety disorders -- Cognitive and mental disorders due to general medical conditions -- Substance-related disorders -- Somatoform and associated disorders -- Sexual and gender issues -- Eating disorders -- Impulse disorders -- Child psychiatry -- Legal issues and forensic psychiatry.
  • Psychiatry. 6th ed. Lane Catalog record
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    "In this sixth edition of NMS Psychiatry, each chapter as well as the drug appendix has been updated to include the latest medications and treatment protocols. New chapters have been added on the emerging fields of emergency and geriatric psychiatry ..."--Provided by publisher.
  • Psychiatry. 7th ed. Lane Catalog record
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  • Psycho-oncology 2014, Springer
    Psycho-oncology is a thriving discipline in cancer care, and numerous research activities have been undertaken in the endeavor to improve treatment outcomes and to gain a better understanding of the psychological consequences of cancer. This book presents and discusses the latest findings from science and practice for a broad range of psychological and social issues related to cancer and its treatments. Not only are general psychosocial impacts of cancer described, but the very common fear of progression is elucidated. The relevance of psychooncology at different stages of disease (during oncological treatment, in rehabilitation, and during palliative care) is explained, and various psychooncological interventions are illustrated. Other important topics are the experience of being a cancer survivor, who may be cured but not be healthy, the psychological burden on relatives, and gender differences in coping with cancer. Quality of life and patient-reported outcomes are also commented on since they are among the key benchmarks for successful coping with the diagnosis of cancer, its treatment, and its late effects.
  • Psycho-oncology. 2nd ed. Lane Catalog record
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  • When the body intrudes: psychotherapy with older and medically ill adults -- Technology, idealization, and unconscious dynamics in the culture of medicine -- Trauma of medical illness -- Narcissistic aspects of aging and illness -- Transference and countertransference in aging and illness -- Self-destructive behaviors, masochistic dynamics, and illness -- Cognitive changes and implications for the therapeutic encounter -- What we know and what we don't: the influence of psychological factors on medical illness -- Hope and grief: the introduction of an emotional language.
  • What is psychodynamic psychotherapy? -- Treatment for a mind in motion -- How does psychodynamic psychotherapy work? -- Evaluation -- Creating a safe place and beginning the evaluation -- Assessment of ego function -- Formulation: the problem, person, goals, resources model -- Indications for psychodynamic psychotherapy -- Beginning the treatment -- Informed consent and setting goals -- Setting the frame and establishing boundaries -- Developing a therapeutic alliance -- Therapeutic neutrality -- Conducting a psychotherapy session: decisions about length and frequency -- Our patients' feelings about us and our feelings about our patients -- Empathic listening -- Looking for meaning -- Medication and therapy -- Listen/reflect/intervene -- Learning to listen -- Learning to reflect -- Learning to intervene -- Conducting a psychodynamic psychotherapy: technique -- Affect -- Free association and resistance -- Transference -- Countertransference -- Unconscious conflict and defense -- Dreams -- Meeting therapeutic goals -- Improving self-perceptions and the ability to regulate self-esteem -- Improving relationships with others -- Improving characteristic ways of adapting -- Improving other ego functions -- Working through and ending -- Working through -- Termination -- Continuing to learn.
  • The disability paradigm / David Pfeiffer -- Understanding how disability is defined and conceptualized in the literature / Barbara J. Lutz and Barbara J. Bowers -- An integrative conceptual framework of disability : new directions for research / Denise G. Tate and Constance Pledger -- Transforming psychological practice and society : policies that reflect the new paradigm / Carol J. Gill, Donald G. Kewman, and Ruth W. Brannon -- Social work practice with people with disabilities in the era of disability rights / Richard L. Beaulaurier and Samuel H. Taylor -- Models of disability : implications for the counseling profession / Julie F. Smart and David W. Smart -- The contribution of the physically and mentally handicapped to development / Jean Vanier -- Personal perspective : coping with a journey toward recovery : from the inside out / Dale Walsh -- Psychological adaptation to chronic illness and disability : a primer for counselors / Hanoch Livneh and Richard F. Antonak -- Objective self-awareness and stigma : implications for persons with visible disabilities / Andrew A. Phemister and Nancy M. Crewe -- Psychosocial issues of women with physical disabilities : the continuing gender debate / Margaret A. Nosek and Rosemary B. Hughes -- Female sexuality and spinal cord injury : counselling implications / Eva Miller and Irmo Marini -- Cross-cultural counseling issues of males who sustain a disability / Irmo Marini -- Psychiatric and psychological issues in survivors of major disasters / Carol S. North -- Quality of life and psychosocial adaptation to chronic illness and acquired disability : a conceptual and theoretical synthesis / Malachy Bishop -- Six principles relating disability and psychological adjustment / Franklin C. Shontz -- Personal perspective : using rational emotive behavior therapy techniques to cope with disability / Albert Ellis -- Family decision making in foregoing life-extending treatments / Virginia P. Tilden ... [et al.] -- My child is not my carer : mothers with physical disablities and the well-being of children / Ora Prilleltenshy -- Parenting a child with a chronic medical condition / Jane Case-Smith -- In the midst of a hurricane : a case study of a couple living with AIDS / Lydia P. Buki, Lori Kogan, Bethanne Keen, and Patti Uman -- Parental illness, family functioning, and adolescent well-being : a family ecology framework to guide research / Sara Pedersen -- Life's challenges : curse or opportunity? Counseling families of persons with disabilities / Mary R. Hulnick and H. Ronald Hulnick -- Personal perspectives : my life with muscular dystrophy : lessons and opportunities / Robert P. Winske -- Dealing with Spina Bifida : mother's perspective / Janet Lingerman -- The construct of hope in the rehabilitation process / Amy B. Collins and Marvin D. Kuehn -- Spirituality in disability and illness / Judy Kaye and Senthil Kumar Raghavan -- Spiritual factors and adjustment in medical rehabilitation : understanding forgiveness as a means of coping / Jon R. Webb -- The psychosocial impact on survivors of extraordinary, stressful, and traumatic events : principles and practices in critical incident response for rehabilitation counselors / Mark A. Strebnicki -- War, death, and bereavement : how we can help / Joan Beder -- Users of assistive technology : the human component / Martin G. Brodwin, Tristen Star, and Elizabeth Cardoso -- Changes in attitudes toward people with handicaps / Beatrice A. Wright -- Personal perspective : recovery and the rehabilitation process : a personal journey / James T. Herbert -- The implications of positive psychology and wellness for rehabilitation counselor education / Irmo Marini and Mitka Chacon -- "Successful aging" : a disability perspective / Meredith Minkler and Pamela Fadem -- The promise of the International classification of functioning, disability, and health (ICF) -- Recovery from psychiatric disabilities / Patricia B. Nemec and Cheryl J. Gagne -- Psychological adaptation to disability : perspectives from chaos and complexity theory / Hanoch Livneh and Randall M. Parker -- Eugenics, euthanasia, and physician-assisted suicide : an overview for rehabilitation professionals / Steve Zanskas and Wendy Coduti -- Reflections and considerations / Arthur E. Dell Orto and Paul Power -- Aging and disability : toward a unified agenda / Irving Kenneth Zola -- Personal statement : life lessons taught me by my disability / Alfred H. DeGraff -- Personal statement : one more burden, a mother's perspective / Bernadette.
  • "One of the hallmarks of generalized anxiety disorder, along with diffuse pathological worry and somatic complaints, is its resistance to therapy. Of available treatment modalities for GAD, cognitive-behavioral therapy garners the best empirical support in terms of successful long-term results. Psychological Approaches to Generalized Anxiety Disorder offers clinicians a wide variety of CBT strategies to help clients develop core anxiety-reduction skills, presented so that readers can hone their own clinical skills. Concise without skimping on information, this book reviews current theory and research, and addresses important diagnostic issues." "Psychological Approaches to Generalized Anxiety Disorder has much information of interest to new and seasoned clinicians, clinical researchers, and academic psychologists. It is also an especially valuable reference for graduate students treating or studying the anxiety spectrum."--BOOK JACKET.
  • Psychoneuroimmunology and cancer : incidence, progression, and quality of life -- Inflammation, chronic disease, and cancer : is psychological distress the common thread? -- Psychological aspects of hereditary cancer risk counseling and genetic testing -- Mastectomy to prevent breast cancer : psychosocial aspects of women's decision-making -- Decision aids in advanced cancer -- Cancer fatalism : attitudes toward screening and care -- Positive psychology perspectives across the cancer continuum : meaning, spirituality, and growth -- Stress, coping, and hope -- Religiousness and spirituality in coping with cancer -- Controversies in psycho-oncology -- Psychosocial interventions for couples coping with cancer : a systematic review -- The impact of cancer and its therapies on body image and sexuality -- Cancer caregivership -- Psychosocial interventions in cancer -- Quality of life -- Exercise for cancer patients : treatment of side effects and quality of life -- Use of the classic hallucinogen Psilocybin for treatment of existential distress associated with cancer -- The placebo and nocebo effects in cancer treatment -- Psychological factors and survivorship : a focus on post-treatment cancer survivors -- Complementary mind-body therapies in cancer -- End-of-life communication in cancer care -- The intersection between cancer and caregiver survivorship -- Resources for cancer patients -- Bringing it all together.
  • Part I: Basic concepts -- American Psychiatric Association -- Characteristics of effective hostage/crisis negotiators -- Cross-trained versus cross-qualified -- Non-law enforcement negotiators -- One on one just isn't right -- Stress and the hostage/crisis negotiator -- Part II: Dealing with the other victim -- Negotiating with normal people -- Negotiating with the adolescent hostage taker -- Negotiating with the inadequate personality -- The antisocial personality disorder (it's all about me!) hostage-taker -- Negotiating with the paranoid schizophrenic hostage-taker -- The bipolar (I'm focused and flying high!) hostage-taker -- The suicidal hostage-holder -- Police-assisted suicide -- Crisis negotiations in the correctional setting -- Negotiating with the extremist -- Part III: Crisis resolution indicators -- Indicators of subject surrender -- Indicators of volatile negotiations -- Part IV: Group dynamics -- Group think -- Creative criteria for constructive deviation from crisis negotiation guidelines -- Part V: Hostage issues -- Phases of a hostage crisis -- The Stockholm syndrome -- What do you say to a hostage?
  • Psychological Co-morbidities of Obesity -- Psychological Issues in Adults with Type 2 Diabetes -- Psychological Co-morbidities of Cardiovascular Disease -- Psychological Co-morbidities of Cancer -- Tobacco Addiction and Psychological Co-morbidities -- Psychological Co-morbidities of HIV/AIDS -- Psychological Co-morbidities in Patients with Pain -- Psychiatric Disorders, Stress, and Their Treatment Among People with Multiple Sclerosis -- Psychological Co-morbidities of Dementia -- Psychological Co-morbidities of Irritable Bowel Syndrome -- Psychological Co-morbidities of COPD.
  • Introduction to psychological experiments on the Internet -- Decision making in the lab and on the Web / Michael H. Birnbaum -- Validity of Web-based psychological research / John H. Krantz and Reeshad Dalal -- A brief history of Web experimenting / Jochen Musch and Ulf-Dietrich Reips -- The Web experiment method : advantages, disadvantages, and solutions / Ulf-Dietrich Reips -- Potential of the Internet for personality research / Tom Buchanan -- Human sexual behavior : a comparison of college and Internet surveys / Robert D. Bailey, Winona E. Foote, and Barbara Throckmorton -- An intercultural examination of facial features communicating surprise / Donatella Pagani and Luigi Lombardi -- What are computing experiences good for? : a case study in online research / John H. Mueller, D. Michele Jacobsen, and Ralf Schwarzer -- PsychExps : an online psychology laboratory / Kenneth O. McGraw, Mark D. Tew, and John E. Williams -- Techniques for creating and using Web questionnaires in research and teaching / Jonathan Baron and Michael Siepman -- The Cognitive Psychology Online Laboratory / Gregory Francis, Ian Neath, and Aimee Surprenant -- The server side of psychology Web experiments / William C. Schmidt.
  • Development of a new assessment strategy in psychosomatic medicine: the diagnostic criteria for psychosomatic research / S. Fabbri ... [et al.] -- Psychosocial approach to endocrine disease / N. Sonino, E. Tomba, G.A. Fava -- Psychological factors affecting functional gastrointestinal disorders / P. Porcelli, O. Todarello -- Psychological factors affecting oncology conditions / L. Grassi ... [et al.] -- Psychological factors affecting cardiologic conditions / C. Rafanelli ... [et al.] -- Toward a biopsychosocial approach to skin diseases / A. Picardi, P. Pasquini -- Psychological factors affecting medical conditions in consultation-liaison psychiatry / A. Bellomo ... [et al.] -- Psychological factors affecting medical conditions in consultation-liaison psychiatry / A. Bellomo ... [et al.] -- Psychological factors affecting eating disorders / S. Fassino ... [et al.].
  • Chapter 1. Understanding PFA -- Chapter 2. How to help responsibly -- Chapter 3. Providing PFA -- Chapter 4. Caring for yourself & your colleagues -- Chapter 5. Practise what you have learned.
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    Part I. Assessment and diagnosis -- 1. Lifetime prevalence of mental disorders in the general population / Christie P. Karpiak and Brian A. Zaboski -- 2. Conducting a mental status examination / Robert W. Baker and Paula T. Trzepacz -- 3. Improving diagnostic and clinical interviewing / Rhonda S. Karg, Arthur N. Wiens, and Ryan W. Blazei -- 4. Increasing the accuracy of clinical judgment (and thereby improving patient care) / David Faust -- 5. Assessing suicidal risk / Kenneth S. Pope and Melba J.T. Vasquez -- 6. Assessment of malingering on psychological measures / Richard Rogers and Nathan D. Gillard -- 7. Identifying and assessing alcohol, drug, and tobacco use disorders / Linda Carter Sobell, Mark B. Sobell, and Sean M. Robinson -- 8. Interviewing children's caregivers / Carolyn S. Schroeder and Eve-Lynn Nelson -- 9. Evaluating the medical components of childhood developmental and behavioral disorders / Nhung T. Tran and James L. Lukefahr -- 10. Using the DSM-5 and ICD-11 in forensic and clinical applications with children across racial and ethnic lines / Ronn Johnson -- 11. Assessing strengths in clinical practice / Tayyab Rashid -- 12. Evaluating dementia / Elise Caccappolo -- 13. Using the International Classification of Diseases system (ICD-10) / Michael C. Roberts and Spencer C. Evans -- 14. Taking a client's sexual history / Judith C. White -- 15. Screening for sexual offender risk / David Medoff and Sarah J. Sternlieb -- 16. Assessing personality disorders / Whitney L. Gore and Thomas A. Widiger. Part II. Psychological testing -- 17. Adult neuropsychological assessment / Aaron P. Nelson and Margaret O'Connor -- 18. Developmental neuropsychological assessment / Jane Holmes Bernstein, Betsy Kammerer, and Celiane Rey-Casserly -- 19. Assessment and intervention for executive dysfunction / Robert M. Roth, Peter K. Isquith, and Gerard A. Gioia -- 20. Assessing and managing concussion / Gerard A. Gioia -- 21. Assessing MMPI-2 profile validity / James N. Butcher -- 22. Interpreting clinical scale scores on the MMPI-2 / John R. Graham -- 23. Interpreting supplementary scales of the MMPI-2 / Roger L. Greene and Lacey M. Sommers -- 24. Understanding and using the MMPI-2-RF / Yossef S. Ben-Porath -- 25. Interpreting the family of Millon clinical inventories / Seth Grossman and Theodore Millon -- 26. Interpreting test scores and their percentile equivalents / Thomas P. Hogan -- 27. Locating information about psychological tests and measures / Thomas P. Hogan -- 28. Applying Rorschach assessment / Irving B. Weiner -- 29. Assessing the quality of a psychological testing report / Gerald P. Koocher and Celiane Rey-Casserly. Part III. Individual adult treatment -- 30. Compendium of psychotherapy treatment manuals / Michael J. Lambert -- 31. Compendium of empirically supported treatments / Dianne L. Chambers and E. David Klonsky -- 32. Compendium of treatment adaptations / John C. Norcross and Bruce E. Wampold -- 33. Compendium of evidence-based therapy relationships / John C. Norcross and Michael J. Lambert -- 34. Applying the stages of change / James O. Prochaska, John C. Norcross, and Carlo C. Diclemente -- 35. Enhancing patient adherence to treatment / M. Robin Dimatteo -- 36. Treating and managing care of the suicidal patient / Bruce Bongar and Glenn R. Sullivan -- 37. Intervening with clients in crisis / Kenneth France -- 38. Treating borderline personality disorder / Kenneth N. Levy -- 39. Treating reluctant and involuntary clients / Stanley L. Brodsky and Caroline Titcomb -- 40. Conducting motivational interviewing / Theresa B. Moyers and Daniel J. Fischer -- 41. Assessing and treating attention-deficit/hyperactivity disorder / Robert J. Resnick -- 42. Assessment and treatment of anger as a clinical problem / Raymond Digiuseppe -- 43. Diagnosis, assessment, and treatment of female sexual dysfunctions / Leonard R. Derogatis and Lori A. Brotto -- 44. Diagnosis, assessment, and treatment of male sexual dysfunctions / Leonard R. Derogatis and Lori A. Brotto -- 45. Working with patients at risk for HIV and other sexually transmitted diseases / Michael P. Carey and Peter A. Vanable -- 46. Treating women in psychotherapy / Laura S. Brown -- 47. Psychotherapy with lesbian, gay, and bisexual clients / Kristin A. Hancock -- 48. Practicing psychotherapy with older adults / Brian D. Carpenter and Bob G. Knight -- 49. Managing sexual feelings for patients in psychotherapy / Kenneth S. Pope -- 50. Improving completion of therapeutic homework / Michael A. Tompkins -- 51. Conducting evaluations of client outcomes and satisfactions / Michael J. Lambert and Kara Cattani -- 52. Repairing ruptures in the therapeutic alliance / Jeremy D. Safran and Catherine Boutwell -- 53. Reducing resistance in psychotherapy / Clifton W. Mitchell -- 54. Implementing stimulus control therapy for insomnia / Richard R. Bootzin -- 55. Terminating psychotherapy / Oren Shefet and Rebecca Coleman Curtis -- 56. Using hypnosis to invite relaxation / Douglas Flemons -- 57. Working with the religiously committed client / P. Scott Richards -- 58. Practicing psychotherapy with adults who have cognitive impairments / Kathleen B. Kortte -- 59. Selecting a treatment format / Larry B. Feldman -- 60. Treating the effects of psychological trauma / Laura S. Brown -- 61. Working with patients who have been sexually abused by previous therapists and clergy / Kenneth S. Pope -- 62. Counseling people living with HIV / Priscilla Dass-Brailsford -- 63. Treating bipolar spectrum disorders / Elizabeth Brondolo -- 64. Tailoring treatments to the patient's race and ethnicity / Guillermo Bernal and Melanie M. Domenech Rodríguez -- 65. Considerations in treating people with disabilities / Rochelle Balter -- 66. Practicing harm reduction / Andrew Tatarsky -- 67. Therapy with victims of hate crimes / Glenda M. Russell and Christopher G. Hawkey -- 68. Assessing and treating nonsuicidal self-injury / E. David Klonsky -- 69. Conducting psychotherapy with clients when English is not the first language / Rafael Javier and Lillian Comas-Díaz -- 70. Understanding sexuality in the context of disability / Linda R. Mona and Kimberly Smith -- 71. Helping patients cope with chronic medical illness / Carol D. Goodheart and Korey K. Hood -- 72 Locating the best research evidence for evidence-based practice / Lauren A. Maggio and Marilyn L. Tinsley -- 73. Preventing relapse / Katie Witkiewitz. Part IV. Couples, family, and group treatment -- 74. Recruiting, selecting, and preparing patients for interpersonal group psychotherapy / Victor J. Yalom -- 75. Conducting parent management training / Melanie M. Nelson and Sheila M. Eyberg -- 76. Conducting couple and family therapy / Jay L. Lebow -- 77. Treating high-conflict couples / Susan Heitler -- 78. Treating partner infidelity / Don-David Lusterman -- 79. Conducting psychoeducational groups / Gary M. Burlingame and Sean Woodland -- 80. Using genograms in assessment and therapy / Sueli S. Petry and Monica McGoldrick -- 81. Treating bullying behaviors among youth / Susan M. Swearer -- 82. Treating enuresis and encopresis / Patrick C. Friman -- 83. Treating veterans and military families / Marjan Ghahramanlou-Holloway and Jennifer L. Bakalar -- 84. Assessing and treating autism spectrum disorders / James A. Mulick and Courtney E. Rice. Part V. Child and adolescent treatment -- 85. Treating the behaviorally disordered child / Sheila M. Eyberg -- 86. Helping children cope with chronic mental illness / Lauren Mednick -- 87. Engaging the reluctant adolescent / Alice K. Rubenstein -- 88. Interviewing children about sexual abuse / Karen J. Saywitz and Joyce S. Dorado -- 89. Treating child sexual abuse / Kathryn Kuehnle and Mary Connell. Part VI. Biology and pharmacotherapy -- 90. Adult psychopharmacology / Christine Blasey, Joseph K. Belanoff, Charles Debattista, and Alan F. Schatzberg -- 91. Understanding side effects and warnings in psychopharmacology / Elain Orabona Foster and Ruth Roa-Navarrete -- 92. Pediatric psychopharmacology / Colleen A. Ryan and Michael L. Trieu -- 93. Common drugs of abuse and their effects / Christopher J. Correia and James G. Murphy -- 94. Herbal treatments for psychological disorders / Paula J. Biedenharn and Brian A. Kiernan -- 95. Medical conditions that may present as psychological disorders / William J. Reed -- 96. Normal medical laboratory values and measurement conversions / Gerald P. Koocher -- 97. Use of height and weight assessment tools / Nancie H. Herbold and Sari Edelstein -- 98. Dietary supplements and psychological functioning / Sari Edelstein and Nancie H. Herbold. Part VII. Self-help resources -- 99. Recommended self-help books, autobiographies, and films / John C. Norcross and Linda F. Campbell -- 100. Recommended homework during psychotherapy with couples and individuals / Arthur E. Jongsma, Jr. -- 101. Recommended self-help Internet resources for patients / John M. Grohol -- 102. Recommended online computer-assisted treatments / Luciano L'Abate. Part VIII. Ethical and legal issues -- 103. Ethical principles of psychologists and code of conduct -- 104. Dealing with licensing boards and ethics complaints / Gerald P. Koocher and Patricia Keith-Spiegel -- 105. Defending against legal (malpractice and licensing) complaints / Robert Henley Woody -- 106. Minimizing your legal liability risk following adverse events of patient threats / Jeffrey N. Younggren -- 107. Dealing with subpoenas / Linday Childress-Beatty and Gerald P. Koocher -- 108. Confronting an unethical colleague / Patricia Keith-Spiegel -- 109. Recognizing, assisting, and reporting the impaired psychologist / Gary R. Schoener -- 110. Understanding special education law / Linda Wilmshurst. Part IX. Forensic practice -- 111. Understanding involuntary psychiatric hospitalization / Stuart A. Anfang and Paul S. Appelbaum -- 112. Applying standards for use of physical restraint and seclusion / Thomas Graf -- 113. Understanding legal terms of special interest in mental health practice / Gerald P. Koocher -- 114. Applying the duty to protect and warn / James L. Werth, Jr. and Jennifer Stroup -- 115. Preparing and giving expert testimony / Stanley L. Brodsky and Tess M.S. Neal -- 116. Evaluating competence to stand trial / Carla A. Lourenco -- 117. Conducting a child custody evaluation / Robin M. Deutsch -- 118. Assessing and responding to aggressive and threatening clients / Leon Vandecreek. Part X. Financial and insurance matters -- 119. Handling money matters and gifts in psychological practice / Jeffrey E. Barnett and Allison J. Shale -- 120. Understanding professional liability insurance / Bruce E. Bennett -- 121. Managing your managed care contracts / Gerald P. Koocher -- 122. Setting fees for psychological services / Kavita J. Shah and John C. Norcross -- 123. Navigating adverse managed care decisions / Katherine C. Nordal and Shirley Ann Higuchi. Part XI. Practice management -- 124. Making good referrals / Steven Walfish and Jeffrey Zimmerman -- 125. Prototype mental health records / Gerald P. Koocher -- 126. Fulfilling informed consent responsibilities / Kenneth S. Pope -- 127. Elements of authorization forms to release or request client's records / Edward Zuckerman -- 128. Understanding fundamentals of the HIPAA privacy rule / Alan C. Nessman -- 129. Common clinical abbreviations and symbols / John C. Norcross and Brian A. Zaboski -- 130. Creating a professional living will for psychologists / Stephen A. Ragusea -- 131. Understanding statistics in the research literature / William F. Chaplin and Niketa Kumar -- 132. Selecting and relying on an attorney / Robert Henley Woody -- 133. Managing real-time telepsychology practice / Eve-Lynn Nelson and Teresa A. Lillis -- 134. Optimizing the use of technology in psychology with best practice principles / Marlene M. Maheu, Joseph McMenamin, and Myron L. Pulier -- 135. Practicing in the era of social media / Jeffrey E. Barnett and Keely Kolmes -- 136. Finding, evaluating, and using smartphone applications / Marlene M. Maheu, Myron L. Pulier, and Sylvain Roy. Part XII. Prevention, consultation, and supervision -- 137. Helping people cope with disasters / Eric M. Vernberg and Erin P. Hambrick -- 138. Establishing a consultation agreement / Len Sperry -- 139. Interacting with the media / Lilli Friedland and Florence Kaslow -- 140. Conducting effective clinical supervision / Nicholas Ladany -- 141. Responsibilities and liabilities in supervision / Carol A. Falender and Edward P. Shafranskie -- 142. Cultivating relationships and coordinating care with other health professionals / John C. Linton -- 143. Consulting on end-of-life decisions / James L. Werth, Jr. and Erica Whiting -- 144. Psychotherapist self-care checklist / John C. Norcross and James D. Guy, Jr. -- 145. Conducting evidence-based prevention / Sha'kema M. Blackmon and Elizabeth M. Vera.
  • Psychological issues are increasingly recognised to be of high importance in diabetes management. Understanding the psychosocial barriers facing individuals and their families and being able to provide the tools to support them to overcome those barriers is an essential part of diabetes care.Psychology and Diabetes Care: A Practical Guide is a concise handbook for the practicing diabetes clinician who is interested in gaining a better understanding of their patients, and in learning effective skills to better support patients. The book explores common psychological problems associated with diabetes, gives insight into how diabetes is experienced in children, adolescents and special groups, and provides practical advice on providing psychological support to individuals with this serious long-term condition.
  • Introduction : The psychology of global mobility / Stuart C. Carr -- Human mobility in a global era / Adrian Furnham -- Mixed-methods approaches to contextually grounded research in settings of armed conflict and natural disaster / Kenneth E. Miller -- Ethical psychological practice with geographically mobile individuals and groups / Graham R. Davidson -- Mobility and personality / Irene Hanson Frieze and Man Yu Li -- Identity and global mobility / Phyllis Tharenou -- Global mobility, local economy : it's work psychology, stupid! / Stuart C. Carr -- The psychology of enforced mobility / Wendy Ager and Alastair Ager -- Global mobility and cross-cultural training / Jan Selmer -- Mobility and acculturation / John W. Berry -- Mobility and inclusion / Douglas C. Maynard, Bernardo M. Ferdman, and Tabitha R. Holmes -- New settlement with wellbeing in oppressive contexts : a liberation psychology approach / Sonia Hernández-Plaza ... [et al.] -- Mobility and careers / Kerr Inkson and Kaye Thorn -- Global mobility and bias in the workplace / Astrid Podsiadlowski and Colleen Ward -- Technology, mobility, and poverty reduction / Lori Foster Thompson and Stephen G. Atkins.
  • 1. Introduction -- 2. Paraphilia and lust murder -- 3. Sexual homicide and serial murder : what do we know? -- 4. An integrative model : what do we need? -- 5. The case of Jeffrey Dahmer -- 6. Dahmer, paraphilia, and lust murder : testing the models -- 7. In search of meaning : on theory construction and model building -- 8. Implications and conclusions.
  • "In recent years, psychology of religion has experienced a remarkable comeback: research is expanding rapidly, benefiting from a genial scientific infrastructure. An important issue in psychology over a century ago, only a few decades later it vanished almost completely. Its unexpected international reemergence since the seventies has been facilitated by the work of visionaries with the energy and stamina to revive an entire branch of psychology. In 'Psychology of Religion: Autobiographical Accounts,' a number of these pioneers account for their development in this area, depicting the diverse contexts of their work, the difficulties they had to deal with, and the increasing contemporary possibilities for their field. Critical about their discipline and sometimes about themselves, they offer a unique assessment of the subject and show the way to further research and development. Thought-provoking topics discussed along the way include: The challenge of approaching religion from a psychological perspective; Psychology of religion as a natural extension of mainstream psychology; Why psychology of religion will continue to gain salience over time. 'Psychology of Religion: Autobiographical Accounts' will appeal to readers in general psychology, religious studies, and philosophy of science. Editor Jacob A. Belzen graduated in social sciences (Utrecht, Netherlands), history (Amsterdam, Netherlands), philosophy (Leuven, Belgium) and sciences of religion (Turku, Finland). He is a full professor at the University of Amsterdam, specializing in cultural psychology of religion, while also actively involved in empirical research on the history of his field. Recipient of various international awards, he counts among Europe's best-known psychologists of religion."--Publisher's website.
  • There have been dramatic increases in the financial, emotional, and psychological investment in pets over the past four decades. The increasing importance of animal companions in people's lives has resulted in growing emphasis on the human-animal bond within academic literature. This book introduces practicing and emerging professionals to vital subject matter concerning this growing specialty area by providing an essential framework and information through which to consider the unique contextual backdrop of the human-animal bond.
  • This book addresses the psychological consequences of wounds and the psychological components of wound care, building on contemporary research evidence and presenting practical clinical guidelines. Particular emphasis is given to the psychological impact of both wounds and wound treatment. Implications for practice are discussed, making this book both educational and practical. Psychology of Wounds and Wound Care in Clinical Practice is aimed at clinicians, including GPs, vascular surgeons and physicians, nurses, especially tissue viability nurses, and podiatrists, and is also of interest to academic teachers and researchers.
  • 1. Introdcution to psychology, religion and spirituality -- 2. Science, religion and psychology -- 3. Religious traditions -- 4. Phenomenological approaches to religion and spirituality -- 5. Psychodynamic and relational approaches -- 6. Contemporary approaches and debates -- 7. Fundamentals of human development, religion, and spirituality -- 8. Religion and development in childhood and adolescence -- 9. Religion, spirituality , and development in adulthood -- 10. Religion, spirituality , and physical health -- 11. Religion, spirituality, and mental health -- 12. Practices and religious communities -- 13. Individual religious and spiritual practices -- 14. Helping relationships: counseling and spiritual growth -- 15. Looking Back -- Glossary -- Bibliography -- Author Index -- Subject Index.
  • The nature of the problem -- Mythos and logos -- Psychology's religious roots. Education and the child ; The American dimension ; Some early British religious psychologists ; A Catholic detour ; Religious origins of the concept of "psychology" ; Conclusions -- Psychology of religion. William James' the varieties of religious experience ; Classic psychology of religion ; The demise of classical psychology of religion ; Conclusion -- A boundary problem. John Macmurray ; Reinhold Niebuhr ; Paul Tillich ; Martin Buber ; The Union Theological Seminary connection ; Conclusion -- The authenticity of religious experience -- Religion and psychotherapy. Boston Emmanuel Movement (1906-1929) ; Britain between 1918 and c. 1980 ; The growth movement -- The problem of prayer -- Religion and personality -- The theism question -- Psychology and non-Christian religions -- Religion and psychological theory. Piaget : salvaging Protestantism by other means? ; Freud : the mysterious nature of psychoanalysis ; Gordon W. Allport (1897-1967) : the psychology of an Episcopalian ; Atheism and anti-religious psychology ; Conclusion -- Conclusions, hypotheses, suggestions and a stab at a personal "position statement". Religious doctrines beyond psychology's brief ; Religion and psychology essentially concerned with the same issues ; Religion is an inferior alternative to psychology ; Reconstructing the relationship ; Two issues for historians of psychology ; An attempt at a final position ; Concluding remarks.
  • Psychoneuroimmunology. 4th ed. Lane Catalog record
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  • Psychopathology and the family 2005, ScienceDirect
    Genetics and the family environment / Thalia C. Eley and Jennifer Y.F. Lau -- The role of parenting in the development of psychopathology : an overview of research using the Parental Bonding Instrument / Gemma L. Gladstone and Gordon B. Parker -- Attachment and psychopathology : a lifespan perspective / Judy Ungerer and Catherine McMahon -- Interparental conflict, violence, and psychopathology / Jennifer L. Hudson -- Oppositional and conduct problems / David J. Hawes and Mark R. Dadds -- Attention-deficit/Hyperactivity Disorder (ADHD) and the family : a developmental psychopathology perspective / Eric J. Mash and Charlotte Johnston -- Family factors and the development of anxiety disorders / Natalie S. Gar, Jennifer L. Hudson and Ronald M. Rapee -- Eating disorders / Tracey Wolfe -- Familial risk factors for substance use disorders / Shelli Avenevoli, Kevin P. Conway, and Kathleen Ries Merikangas -- Parenting and personality disorders / Joel Paris -- Family factors in schizophrenia and bipolar disorder / Jill M. Hooley, Kristen A. Woodberry, and Caitlin Ferriter -- Depression and the family / Judy Garber -- Family involvement in psychotherapy : what's the evidence? / Katharina Manassis -- Clinical perspectives on involving the family in treatment / Frank M. Dattilio -- Family intervention and prevention of behavioural and emotional disorders in childhood and adolescence / Matthew R. Sanders and Alan Ralph.
  • Psychopharmacogenetics 2006, Springer
  • This book examines the role of psychopharmacological treatment in a range of disorders that may be encountered during pregnancy, including major depressive disorders, anxiety disorders, bipolar affective disorder, schizophrenia, eating disorders, and substance abuse. The natural history of each condition pre- and post-partum is analyzed, and the evidence for the efficacy of drug treatments, evaluated. Special attention is paid to the potential dangers of different treatment options for both mother and fetus, covering risks of malformation, pregnancy and obstetric risks, neonatal risks, and possible long-term consequences. The risks of not treating a particular condition are also analyzed. On the basis of the available evidence, management guidelines are provided that additionally take into account non-pharmacological options. Closing chapters consider the value of complementary and alternative medicine and ECT and explore future research directions.
  • This practical manual presents the main drugs and protocols currently used in the psychopharmacological treatment of psychiatric disorders in cancer and palliative care settings and explores the principal issues involved in such treatment. Significant clinical challenges encountered in the psychopharmacological management of various psychiatric conditions are discussed, covering aspects such as side-effects and drug-drug interactions. Attention is also paid to the emerging theme of adjuvant use of psychotropic drugs for the treatment of symptoms or syndromes not primarily related to psychiatric disorders (e.g. pain, hot flashes). In addition, practical suggestions are provided for dealing with special populations, including children, the elderly, and people affected by severe mental illness. The book is designed to be easy to read and to reference: information is clearly displayed in concise tables and boxes, accompanied by further detail within the text and clinical vignettes. The authors include some of the most renowned clinicians working in the field of psycho-oncology.
  • Psychoprosthetics 2008, Springer
  • "Although much of medical practice is research driven, the same cannot be said about the psychosocial interventions for chronic pain and illness. Psychological therapy for pain is dominated by cognitive-behavior therapy, which is demonstrably effective in a significant proportion of chronic pain sufferers. There is a clear need to broaden the base of psychosocial therapies for treating this hugely suffering population. Psychosocial Interventions for Chronic Pain goes a long way to correct the situation by examining the empirical bases of patient problems as well as offering evidence-supported approaches to their management. Ranjan Roy's introductory chapters explain how effectiveness is measured in psychosocial practice, and these concepts are clearly applied in compelling case examples." "Psychosocial Interventions for Chronic Pain brings a useful framework of ideas to all health and mental health professionals working with chronic pain patients, including psychologists, social workers, physicians, and nurses. The book's evidence-based orientation also makes it a valid text for specialized graduate courses on pain management."--Jacket.
  • Principles of psychosomatic assessment / Fava, G.A., Sonino, N., Wise, T.N. -- The psychosomatic interview / Wise, T.N., Dellemonache, P.M.; Bachawati, M.M. -- Evaluating childhood adversity / Thabrew, H., de Sylva, S., Romans, S.E. -- Evaluating life events and chronic stressors in relation to health : stressors and health in clinical work / Theorell, T. -- Assessment of lifestyle in relation to health / Tomba, E. -- Assessment of sexual function in the medically ill : psychosomatic approach to sexual functioning / Balon, R. -- Psychological factors in medical disorders assessed with the diagnostic criteria for psychosomatic research / Porcelli, P., Todarello, O. -- Mood and anxiety in the medically ill / Bech, P. -- Assessment of personality in psychosomatic medicine : current concepts -- Cosci, F. -- Illness behavior / Sirri, L., Grandi, S. -- Assessment of psychological well-being in psychosomatic medicine -- Rafanelli, C., Ruini, C. -- Family assessment in the medical setting / Keitner, G.I. -- Relational ethics and psychosomatic assessment / Barbosa, A.
  • Psychosocial problems appear within a medical context worldwide, and are a major burden to health. Psychosomatic Medicine: An International Primer for the Primary Care Setting takes a uniquely global approach in laying the foundations of biopsychosocial basic care (such as recognizing psychosocial and psychosomatic problems, basic counseling, and collaboration with mental health specialists) and provides relevant information about the most common mental and psychosomatic problems and disorders. The scope of the book is interculturalit addresses global cultures, subcultures living in a single country, and strengthening the care given by physicians working abroad. This clinically useful book outlines best practices for diagnosing the most common biopsychosocialproblems and mastering the most common communication challenges (e.g. doctor-patient conversation, breaking bad news, dealing with difficult patients, family and health systems communication and collaboration). Every chapter integrates basic theoretical background and practical skills and includes trans-culturally sensitive material, important for work with patients from different cultures. Psychosomatic Medicine: An International Primer for the Primary Care Setting serves as an excellent resource for clinicians hoping to gain and develop knowledge and skills in psychosomatic medicine.
  • Psychosurgery, or the surgical treatment of mental disorders, has enjoyed a spectacular revival over the past ten years as new brain stimulation techniques have become available. Neuromodulation offers new possibilities for the treatment of psychiatric disorders such as depression, obsessive-compulsive disorder (OCD), addiction, eating disorders and autism. This work presents the history of this unique specialty and investigates current techniques and ethical challenges. With a wealth of illustrations and detailed anatomical diagrams, it provides essential information for medical practitioners, as well as anyone else interested in the fascinating advances being made in neuroscience today.
  • This book provides readers with essential information on the foundations of psychotherapy research, and on its applications to the study of both psychotherapy process and outcome. The aim is to stimulate a reflection on these issues in a way that will benefit researchers and clinicians, as well as undergraduate and graduate students, at different levels and from different perspectives. Accordingly, the book presents a balanced mix of chapters summarizing the state of the art in the field from different viewpoints and covering innovative topics and perspectives, reflecting some of the most established traditions and, at the same time, emerging approaches in the field in several countries. The contributors, who were invited from among the experts in our national and international professional networks, also represent a healthy mix of leading figures and young researchers. The first part of the book addresses a number of fundamental issues in psychotherapy research at a historical, philosophical, and theoretical level. The second part of the book is concerned with research on psychotherapy processes; in this regard, both quantitative and qualitative approaches are given equal consideration in order to reflect the growing relevance of the latter. The book?s third and last part examines research on psychotherapy outcomes, primarily focusing on quantitative approaches. Offering a balanced mix of perspectives, approaches and topics, the book represents a valuable tool for anyone interested in psychotherapy research.
  • Variations on a Theme: What is 'Real' Psychotherapy? -- Unconscious Scenarios: Psychodynamic Therapy -- In contact with yourself: client-centered therapy -- Learning by Doing: Behavior Therapy -- Thinking Differently: Cognitive Therapy -- Joy and Sorrow Together: Systems Therapy -- Tailored Therapy: What do we Measure and What do we Know? -- Pitfalls and Safety Nets: In Good Hands?.
  • Print Material
    Antipsychotics -- Agents for treating movement disorders -- Antidepressants -- Dementia-treating agents -- Mood stabilizers -- Antianxiety agents -- Hypnotics -- Stimulants and stimulant-like agents.
  • Psychotropic drugs. 4th ed. Lane Catalog record
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  • Thirty years since Estelle v. Gamble: looking forward, not wayward / Robert B. Greifinger -- Impact of incarceration on community public safety and public health / Todd R. Clear -- Litigating for better medical care / Jon Wool -- Accommodating disabilities in jails and prisons / R. Samuel Paz -- Growing older: challenges of prison and reentry for the aging population / Brie Williams, Rita Abraldes -- International public health and corrections: models of care and harm minimization / Michael Levy -- The medicalization of execution: lethal injection in the United States / Mark Heath -- HIV and viral hepatitis in corrections: a public health opportunity / Joseph A. Bick -- Prevention of viral hepatitis / Cindy Weinbaum, Karen A. Hennessey -- HIV prevention: behavioral interventions in correctional settings / Barry Zack -- Prevention and control of tuberculosis in correctional facilities / Farah M. Parvez -- Controlling chlamydia, gonorrhea, and syphilis through targeted screening and treatment in correctional settings / Charlotte K. Kent, Gail A. Bolan -- Health promotion in jails and prisons: an alternative paradigm for correctional health services / Megha Ramaswamy, Nicholas Freudenberg -- Screening for public purpose: promoting an evidence-based approach to screening of inmates to improve the public health / Joshua D. Lee, Marshall W. Fordyce, Josiah D. Rich -- Written health informational needs for reentry / Jeff Mellow -- Reducing inmate suicides through the mortality review process / Lindsay M. Hayes -- Blinders to comprehensive psychiatric diagnosis in the correctional system / Richard L. Grant -- Juvenile corrections and public health collaborations: opportunities for improved health outcomes / Michelle Staples-Horne, Kaiyti Duffy, Michele T. Rorie -- Female prisoners and the case for gender-specific treatment and reentry programs / Andrea F. Balis -- Building the case for oral health care for prisoners: presenting the evidence and calling for justice / Henrie M. Treadwell, Mary E. Northridge, Traci N. Bethea -- Treatment of mental illness in correctional settings / Raymond F. Patterson, Robert B. Greifinger -- Treatment and reentry approaches for offenders with co-occurring disorders / Roger H. Peters, Nicole M. Bekman -- Pharmacological treatment of substance abuse in correctional facilities: prospects and barriers to expanding access to evidence-based therapy / R. Douglas Bruce, Duncan Smith-Rohrberg, Frederick L. Altice -- Health research behind bars: a brief guide to research in jails and prisons / Nicholas Freudenberg -- Reentry experiences of men with health problems / Christy A. Visher, Kamala Mallik-Kane -- Providing transition and outpatient services to the mentally ill released from correctional institutions / Steven K. Huge -- Sexual predators: diversion, civil commitment, community reintegration, challenges, and opportunities / Karen Terry -- Electronic health records systems and continuity of care / Ralph P. Woodward -- Community health and public health collaborations / Thomas Lincoln, John R. Miles, Steve Scheibel -- Improving the care for HIV-infected prisoners: an integrated prison-release health model / Sandra A. Springer, Frederick L. Altice.
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  • Public health entomology 2013, CRCnetBASE
    "Increasing problems of emerging and re-emerging infectious diseases, brought about, at least in part, by vectors fueled by increased worldwide travel and commerce, make this a highly timely book for anyone in the public practice of medical and veterinary entomology, including entomologists, public health officials, and pest control technicians and managers. Employing a reader-friendly style with bulleted texts, scenarios, and case history boxes, it targets the major vectors and pests of medical and public health importance, addresses regulatory and academic medical entomology, and discusses disease vector control with worldwide application"--Provided by publisher.
  • Part I. Context for Public Health Informatics -- 1. Introduction to Public Health Informatics / J.A. Magnuson and Patrick W. O'Carroll -- 2. History and Significance of Information Systems and Public Health / John R. Lumpkin and J.A. Magnuson -- 3. Context and Value of Biomedical and Health Informatics / William R. Hersh -- 4. Governmental and Legislative Context of Informatics / Margo Edmunds -- Part II. The Science of Public Health Informatics -- 5. Public Health Informatics Infrastructure / Brian E. Dixon and Shaun J. Grannis -- 6. Information Architecture / Dina Dickerson and Patricia Yao -- 7. Data Sources and Data Tools / Edward Mensah and Johanna L. Goderre -- 8. Public Health Information Standards / J.A. Magnuson, Riki Merrick, and James T. Case -- 9. Privacy, Confidentiality, and Security of Public Health Information / William A. Yasnoff -- 10. Electronic Health Records / Stephen P. Julien -- 11. Ethics, Information Technology, and Public Health: Duties and Challenges in Computational Epidemiology / Kenneth W. Goodman and Eric M. Meslin -- 12. Project Management and Public Health Informatics / James Aspevig -- 13. Evaluation for Public Health Informatics / Paul C. Fu, Jr., Herman Tolentino, and Laura H. Franzke -- Part III. Key Public Health Information Systems -- 14. Informatics in Disease Prevention and Epidemiology / Richard S. Hopkins and J.A. Magnuson -- 15. Informatics in Toxicology and Environmental Public Health / Edwin M. Kilbourne -- 16. Public Health Laboratories / Riki Merrick, Steven H. Hinrichs, and Michelle Meigs -- 17. The National Vital Statistics System / Charles J. Rothwell, Mary Anne Freedman, and James A. Weed -- 18. Risk Factor Information Systems / Alan Tomines -- 19. Setting national Policies and Standards for Immunization Information Systems / Nedra Y. Garrett -- Part IV. New Challenges and Emerging Solutions -- 20. New Means of Data Collection and Accessibility / I. Charie Faught, James Aspevig, and Rita Spear -- 21. Geographic Information Systems / Carol L. Hanchette -- 22. Public Health Informatics and Health Information Exchange / J.A. Magnuson and Paul C. Fu, Jr. -- 23. Decision Support and Expert Systems in Public Health / William A. Yasnoff and Perry L. Miller -- 24. Delivery of Preventive Medicine in Primary Care / Paul C. Fu, Jr., Alan Tomines, and Larry L. Dickey -- 25. Case-Based Learning in Public Health Informatics / Herman Tolentino, Sridhar R. Papagari Sangareddy, Catherine Pepper, and J.A. Magnuson -- Part V. Case Studies: Information Systems and the Strata of Public Health -- 26. Local and Regional Public Health Informatics / Jeffrey M. Kriseman and Brian J. Labus -- 27. Public Health Informatics in High Population States: New York and Ohio / Geraldine S. Johnson, Guthrie S. Birkhead, Rachel Block, Shannon Kelley, James Coates, Bob Campbell, and Brian Fowler -- 28. State Public Health Informatics: Perspective from a Low Population State / James Aspevig -- 29. National Public Health Informatics, United States / Seth Foldy -- 30. Public Health Informatics in Canada / Lawrence E. Frisch, Elizabeth M. Borycki, Alyse Capron, Abla Mawudeku, and Ronald St. John -- 31. Perspectives on Global Public Health Informatics / Janise Richards, Gerry Douglas, and Hamish S.F. Fraser -- Part VI. Epilogue -- 32. Public Health Informatics: The Path Forward / J.A. Magnuson.
  • Public health of Japan 2006 Lane Catalog record
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  • Public health of Japan 2008 Lane Catalog record
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  • Introduction / Donald J. Lollar and Elena M. Andresen -- Epidemiology and biostatistics / Elena M. Andresen -- Social and behavioral dimensions of health / Paul Devereaux and Charlie Bullock -- Disability in the health services curriculum / Carol Tobias -- Environmental health and disability / Donald J. Lollar -- Disability and health inequity / Dennis G. Heaphy, Monika Mitra, and Erin D. Bouldin -- Disability and maternal and child health / Debbie Allen -- Aging, disability, and public health / John Crews -- Disability and international health / Mary Chamie -- Disability issues in health care ethics and law in the public health curriculum / Jerome E. Bickenbach -- Section 504 the Rehabilitation Act and the Americans with Disabilities Act in public health education / Dennis G. Heaphy.
  • The role of law : agencies, legislators, courts, and the constitution -- The role of epidemiology and medicine : diagnosis, prevention, control, and evaluation -- The role of economics : theories, modeling, and evaluation -- The role of politics : players, processes, and power -- The role of ethics : historical, contemporary, and future perspectives -- HIV criminalization -- Clean water and mosquito control -- HPV vaccination -- SCHIP and children with special health care needs -- Overweight and obesity -- Breast cancer screening -- Medical transportation : local research focus -- Medical transportation : local practice focus -- Taxes, politics, and public health policy : a look back at the 2008 presidential campaign -- Supplemental nutrition assistance program and modifying behavior -- Medical readmissions and the Affordable Care Act -- Tobacco control and cessation programs -- Emergency preparedness and infectious diseases -- The research policy brief : a primer -- Letters to the editor : a primer.
  • Public health emergencies may arise directly or indirectly from a wide variety of events, including emerging diseases, natural disasters, industrial accidents, and terrorist attacks. One area that has not been examined in much detail is public health emergency preparedness for incidents involving the release of chemical or radiological agents. As part of RAND's continuing research into public health emergency preparedness, this report characterizes the public health service's role in preparing for and responding to such incidents, describes practices in use by local public health departments, and identifies functional areas of public health emergency preparedness and response for chemical and radiological incidents that may warrant further practice development.
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    Evidence concerning the consequences of publication and related biases / Alexander J. Sutton -- Software for publication bias / Michael Borenstein -- Bias in meta-analysis induced by incompletely reported studies / Alexander J. Sutton and Therese D. Pigott -- Assessing the evolution of effect sizes over time / Thomas A. Trikalinos and John P.A. Ioannidis -- Do systematic reviews based on individual patient data offer a means of circumventing biases associated with trial publications? / Lesley Stewart, Jayne Tierney and Sarah Burdett -- Differentiating biases from genuine heterogeneity: distinguishing artifactual from substantive effects / John P.A. Ioannidis -- Beyond conventional publication bias: other determinants of data suppression / Scott D. Halpern and Jesse A. Berlin. Publication bias in meta-analysis / Hannah R. Rothstein, Alexander J. Sutton and Michael Borenstein -- Publication bias: recognizing the problem, understanding its origins and scope, and preventing harm / Kay Dickersin -- Preventing publication bias: registries and prospective meta-analysis / Jesse A. Berlin and Davine Ghersi -- Grey literature and systematic reviews / Sally Hopewell, Mike Clarke and Sue Mallen -- The funnel plot / Jonathan A.C. Sterne, Betsy Jane Becker and Matthias Egger -- Regression methods to detect publication and other bias in meta-analysis / Jonathan A.C. Sterne and Matthias Egger -- Failsafe N or file-drawer number / Betsy Jane Becker -- The trim and fill method / Sue Duval -- Selection method approaches / Larry V. Hedges and Jack Vevea --
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    Overview -- Title and abstract -- Introduction -- Methods -- Results -- Tables -- Figures -- Discussion -- References and electronic publishing -- Authorship -- Posters -- Oral presentations -- Choosing a journal and responding to reviews -- Suggestions for writing well.
  • PubMed help NCBI Bookshelf
    PubMed quick start -- Searching PubMed -- Understanding your search results -- Displaying and sorting your search results -- Changing how search results are displayed -- Finding related resources for a citation -- Viewing your search history -- Displaying the search details -- Printing citations -- Saving and e-mailing results and searches -- My NCBI.
  • Pueraria the genus Pueraria 2002, CRCnetBASE
  • The Essentials in Cytopathology book series fulfills the need for an easy-to-use and authoritative synopsis of site specific topics in cytopathology. These guide books fit into the lab coat pocket and are ideal for portability and quick reference. Each volume is heavily illustrated with a full color art program, while the text follows a user-friendly outline format. This new edition of Pulmonary Cytopathology is fully updated and expanded providing more detailed discussion of the role of new techniques such as EUS needle biopsy and specific issues of adequacy assessment. The section on subclassification of poorly-differentiated non-small cell carcinomas has been expanded to include accuracy of diagnosis in small samples, the new classification of adenocarcinoma and NSCC, currently-used ancillary techniques; i.e., immunohistochemistry, molecular/genetic techniques and therapeutic applications. Molecular techniques have been added as needed for targeted therapy. The text and illustrations have been expanded throughout.
  • Pulmonary embolism. 2nd ed. Lane Catalog record
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    This edition covers the most commonly performed pulmonary function tests separated into individual chapters to allow a full overview of each test. It contains updated material including the latest guidelines and recommendations from the American Thoracic Society ... et al. Each chapter includes: Relevant Physiology; Pertinent Background Information; Technical Factors; Relevant Instrumentation; Respiratory Calculations; Patient Cases; Self-assessment Questions.
  • Pulmonary hypertension 2008, Springer
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  • Part I. Preamble and Introduction -- 1. Managing Patients with Hematological Malignancies for 25 Years / Benoit Schlemmer -- 2. Pulmonary Involvement in Patients with Hematological Malignancies / Élie Azoulay -- 3. Respiratory Infections in Patients with Hematological Malignancies / Ayman O. Soubani -- Part II. Epidemiology -- 4. Epidemiology of Respiratory Events in Patients with HM (Not Including ICU) / Georg Maschmeyer -- 5. Epidemiology of Acute Respiratory Failure in Patients with HM (ICU Only) / Carlos Agustí, Carmen Lucena, and Antoni Torres -- 6. Noninfectious Lung Involvement in Patients with Hematological Malignancies (Excluding BMT) / Bernard Maitre -- 7. Noninfectious Pulmonary Involvement in Hematopoietic Stem Cell or Bone Marrow Transplant Recipients / Bekele Afessa -- 8. Are There Any Pulmonary Issues Specifically Related to Cord Blood Transplants? / Jonathan Gutman -- 9. Cardiovascular Complications of Cancer Therapeutics / Aarif Y. Khakoo and Callie S. Kwartler -- 10. Prophylaxis: Peace of Mind? / Benoit Guery and Karine Faure -- Part III. Diagnostic Strategy in HM Patients -- 11. How Type of Malignancy and Treatment Assist in the Etiological Diagnosis / Alexandre Boyer and Didier Gruson -- 12. Contribution of Radiology in Patients with Hematological Malignancies and Pulmonary Involvement / Claus Peter Heussel -- 13. Is There Still a Place for Transbronchial Lung Biopsy or Other Lung Biopsy Techniques? / Christophe Dooms and Vincent Ninane -- 14. The Increasing Role for Core Needle Biopsy of Pulmonary Lesions in Immunocompromised Patients / Cédric de Bazelaire, Raphael Calmon, Marion Chapelier, Amélie Pluvinage, and Eric de Kerviler -- 15. Minimally Invasive Diagnostic Strategy in Immunocompromised Patients with Pulmonary Infiltrates / Laurent Camous, Virginie Lemiale, Achille Kouatchet, David Schnell, Sandra de Miranda, and Élie Azoulay -- 16. Pleural Effusions and Thoracentesis in Patients with Hematological Malignancies / Michael G. Alexandrakis, Paschalis Steiropoulos, and Demosthenes Bouros -- 17. Diagnostic Yield of BAL Fluid Cytology in Hematologic Malignancies / Jean-François Bernaudin and Jocelyne Fleury-Feith -- 18. New Methods for Bacterial Diagnosis in Patients with Hematological Malignancies / Agnès Ferroni and Jean-Ralph Zahar -- 19. FDG-PET Imaging in Haematological Patients with Pulmonary Infiltrates / Tomohiko Yamane -- 20. What Has Been Learned from Postmortem Studies? / Stephen M. Pastores, Alina O. Dulu, and Shilpa A. DeSouza -- Part IV. Lung Infections in Patients with HM --21. Common Viral Pneumonia / David Schnell, Jérôme Legoff, and Élie Azoulay -- 22. Emerging Viral Infections / Oliver Schildgen -- 23. Cytomegalovirus Pneumonia in Patients with Hematologic Malignancies / Karen J. Vigil and Roy F. Chemaly -- 24. Herpes Simplex Virus Pneumonia in Patients with Hematologic Malignancies / Jharna N. Shah and Roy F. Chemaly -- 25. Pneumocystis Pneumonia in Non-AIDS Immunocompromised Patients / Élie Azoulay, Virginie Lemiale, Achille Kouatchet, François Vincent, Antoine Roux, Guillaume Bollée, and Patricia Roux -- 26. Diagnosis of Invasive Pulmonary Aspergillosis in Patients with Hematologic Diseases / Marie-Elisabeth Bougnoux, Fanny Lanternier, Emilie Catherinot, Felipe Suarez, and Olivier Lortholary -- 27. Emerging Fungal Infections / Marcia Garnica and Marcio Nucci -- 28. Candida Pneumonia in Patients with Hematological Neoplasia / Carlos Carvajal, Jordi Rello, and Jeffrey Lipman -- 29. Parasitic Lung Infections / Jean-François Timsit, Jean-Paul Brion, and Hervé Pelloux -- 30. Pulmonary Mycobacterial Infections in Patients with Hematological Malignancies / Khalid A. Al-Anazi and Asma M. Al-Jasser -- Part V. Noninfectious Pulmonary Involvement in Patients with HM -- 31. Pleuropulmonary Changes Induced by Drugs in Patients with Hematologic Diseases / Philippe Camus -- 32. Cardiovascular Complications of Cancer and Radiation Therapy / Callie S. Kwartler and Aarif Y. Khakoo -- 33. Diffuse Alveolar Hemorrhage in Hematopoietic Stem Cell Transplant Recipients and Patients with Hematologic Malignancy / Bekele Afessa -- 34. Venous Thromboembolism in Patients with Hematologic Malignancies / Tarek Sousou and Alok A. Khorana -- 35. Transfusion-Related Acute Lung Injury in Children with Hematological Malignancies / Rachel S. Bercovitz, J. Bradley Ball, Marguerite R. Kelher, and Christopher C. Silliman -- 36. Acute Respiratory Distress Syndrome (ARDS) in Neutropenic Patients / Mokart Djamel, Textoris Julien, Ettori Florence, Bruno Chetaille, and Blache Jean-Louis -- 37. Pulmonary Venoocclusive Disease Following Hematopoietic Stem Cell Transplantation / Matthew C. Bunte and Linda J. Burns -- 38. Radiation Pneumonitis / Miguel Gallego Díaz and Jordi Rello Condomines -- 39. Leukostasis, Infiltration and Pulmonary Lysis Syndrome Are the Three Patterns of Leukemic Pulmonary Infiltrates / François Vincent -- 40. Pulmonary MALT Lymphoma: Clinical, Molecular and Therapeutic Aspects / Marie Wislez, Raphael Borie, Catherine Thieblemont, Marie-France Carette, Martine Antoine, and Jacques Cadranel -- 41. ARDS During Neutropenia Recovery / Élie Azoulay, Eric Ezingeard, Choupi-Salomon Berckowski, and Michael Darmon -- 42. Fibrosing Alveolitis in Hematologic Malignancy Patients Undergoing Hematopoietic Cell Transplantation / Huda Salman, Kenneth R. Cooke, and Hillard M. Lazarus -- Part VI. Treatment and Difficult Decisions in Patients with HM and ARF -- 43. Antibiotic Therapy in Neutropenic Patients / Matthieu Legrand, Adeline Max, and Bertrand Gachot -- 44. Antifungal Therapy in Patients with Hematological Malignancies / Raoul Herbrecht and Yasmine Nivoix -- 45. Antiviral Agents in Patients with Hematological Malignancies and Acute Respiratory Failure / Michael Sandherr -- 46. Mechanical Ventilation in Patients with Hematological Malignancies / Márcio Soares, Jorge I.F. Salluh, and Pieter O. Depuydt -- 47. Optimizing Noninvasive Ventilation in Hematological Patients with Acute Respiratory Failure / Gilles Hilbert -- 48. Noninvasive Ventilation to Ensure the Safety of Fiberoptic Bronchoscopy / Massimo Antonelli, Giuseppe Bello, and Riccardo Maviglia -- 49. NIV Outside the ICU / Stefano Nava and Sebastiano Mercadante -- 50. Palliative Noninvasive Mechanical Ventilation in Patients with Hematological Malignancies / Anne-Pascale Meert, Thierry Berghmans, and Jean-Paul Sculier -- 51. Acute Kidney Injury in Cancer Patients / Michael Darmon, Laurent Camous, Camille Devanlay, Emmanuel Canet, Benoit Schlemmer, and Fabrice Zeni -- 52. Septic Shock / David Grimaldi and Frédéric Pène -- 53. Prognostic Factors for Mortality in the Critically Ill Cancer Patient / Kathleen N.S. Cathcart and Jeffrey S. Groeger -- 54. Managing Critically Ill Cancer Patients: Another Medical Success Story / Élie Azoulay, Marcio Soares, Michael Darmon, Dominique Benoit, Stephen Pastores, and Bekele Afessa -- 55. Palliative Care and Dyspnea Management in Patients with Hematological Malignancies and Acute Respiratory Failure / Amy P. Abernethy, Jane L. Wheeler, and David C. Currow -- 56. End-of-Life Decisions in Cancer Patients / Lieve Van den Block, Agnes van der Heide, and Luc Deliens -- Part VII. Pearls That You Should be Aware Of -- 57. An Unexpected Diagnosis of Pulmonary Tuberculosis / Virginie Lemiale, A. Seguin, and Élie Azoulay -- 58. Respiratory Symptoms Occurring 4 Months After Allogeneic Hematopoietic Stem Cell Transplantation / Anne Bergeron, Séverine Feuillet, Véronique Meignin, Patricia Ribaud, and Abdellatif Tazi -- 59. Pulmonary Complications of Chronic Lymphocytic Leukemia / Melhem Solh and Punit Wadhwa -- 60. Clinical Pearls: Pulmonary Veno-occlusive Disease / Jonathan Gutman -- 61. Cytarabine-Induced Pulmonary Toxicity in Leukemic Patients / Fabio Forghieri, Leonardo Potenza, Monica Morselli, Monica Maccaferri, Giuseppe Torelli, and Mario Luppi -- 62. Histoplasmosis in a Patient with Chronic Myelogenous Leukemia / Vincent Peigne, Benoît Schlemmer, and Olivier Lortholary -- 63. Pulmonary Toxicity of Imatinib and Other BCR-ABL Tyrosine Kinase Inhibitors / François Vincent -- 64. Rituximab-Related Pulmonary Toxicity / Yair Herishanu, Chava Perry, and Aaron Polliack -- 65. Cardiogenic Causes of Respiratory Failure in Patients with Hematological Malignancies / Julien Maizel, Berengere Gruson, Jean-Pierre Marolleau, and Michel Slama -- 66. Pulmonary Alveolar Proteinosis / François Vincent, H. Tandjaoui, and P.Y. Brillet -- 67. Pneumocystis jiroveci Pneumonia in a Patient with Diffuse Large B-Cell Lymphoma / Hung Chang and Lee-Yung Shih -- 68. Pulmonary Infiltration in Anaplastic T-Cell Lymphoma / Christophe Cracco, Julien Mayaux, Sylvain Choquet, Catherine Beigelman, and Frédéric Charlotte -- 69. A Rapidly Reversible Cause of Pulmonary Embolism / Sophie Georgin-Lavialle, Élie Azoulay, Fabrice Zeni, and Michael Darmon -- 70. Hairy Cell Leukemia with Pulmonary Infiltrates / Virginie Lemiale, Véronique Meignin, and Élie Azoulay -- 71. Trichosporon asahii Infection in a Neutropenic Patient / Djamel Mokart, Antoine Sannini, Jean-Paul Brun, Laurent Chow-chine, and Jean-Louis Blache -- Part VIII. Post Face -- 72. Who Is This Book for? Reserved to Highly Specialized Teams? / Laurent Brochard -- 73. Pulmonary Involvement in Patients with Hematological Malignancies: And Now? / Patricia Ribaud and Gérard Socié.
  • The first comprehensive, practical book strictly focused on diagnosing and treating the full spectrum of respiratory complications of non-pulmonary diseases. Pediatric pulmonologists and other expert specialists present their up-to-date and balanced perspectives on new approaches to therapy and recent advances on everything from HIV/AIDS and transplantation to postoperative complications. The contributors are some of the most distinguished and recognizable physicians in their fields giving you the benefit of accumulated insight and experience.
  • "The spectrum of systemic rheumatologic disease (often termed connective tissue disease) is characterized by autoimmune-mediated organ dysfunction, and the lungs are a frequent target. There are numerous pulmonary manifestations associated with connective tissue diseases, and all patients with rheumatologic disease are at risk of developing associated lung disease. Pulmonary Manifestations of Rheumatic Disease covers the comprehensive management of rheumatologic lung disease, which requires a multi-disciplinary approach and is optimized by active engagement by rheumatologists working closely with pulmonologists and other specialists. The book offers a practical reference using a case-based approach for practicing clinicians in the ongoing assessment and understanding of rheumatologic lung disease, and presents the science and pathophysiology underlying rheumatologic lung diseases. The first text of its kind specifically dedicated to describe diverse, commonplace, and challenging aspects of rheumatologic lung diseases, Pulmonary Manifestations of Rheumatic Disease serves as an invaluable tool for the practicing clinician."--Publisher's website.
  • This book explores engineered nanomaterials (ENM) pulmonary effects and familiarizes readers with unique aspects of nanomaterial application and research. Focusing on the diagnostic and therapeutic utilities of nanomaterials in different lung diseases, it discusses the novel applications of nanotechnology for the treatment of airway diseases such as asthma, allergy, chronic obstructive pulmonary diseases, cystic fibrosis, and lung cancer. In an attempt to synchronize the efforts of pulmonary biologists, chemists, and clinicians in developing novel nano-based tools for airway diseases, the book also discusses the strategies to overcome the pathophysiological and technical barriers.
  • Pulmonary pathology 2008, ClinicalKey
    This volume in the Foundations in Diagnostic Pathology Series packs today's most essential pulmonary pathology into a compact, high-yield format! It covers both common and rare neoplastic and non-neoplastic diseases of the lung and pleura and focuses primarily on diagnosis with correlations to clinical and radiographic characteristics. Its pragmatic, well-organized approach, abundant full-color illustrations, and at-a-glance boxes and tables make the information you need easy to access. Practical and affordable, this resource is ideal for study and review as well as everyday clinical practice! Detailed discussions on today₂s technologies help you select the best test for case evaluation. Chapters devoted to the techniques used in the assessment of pulmonary diseases, including immunohistochemistry, immunofluorescnece, and certain clinical laboratory tests offer you a better understanding of techniques and their application for the diagnosis of lung disease. Internationally recognized pathologists convey the most current information, keeping you on the cusp of your field. More than 800 photomicrographs and gross photographs--most in full color--present important pathologic features, enabling you to form a differential diagnosis and compare your findings with actual cases. Uses a consistent, user-friendly format, including at-a-glance boxes and tables for easy reference.
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    Ventilation -- Gas exchange -- Other tests -- Obstructive diseases -- Restrictive diseases -- Vascular diseases -- Environmental and other diseases -- Respiratory failure -- Oxygen therapy -- Mechanical ventilation.
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    Basic evaluation: symptoms/problem based. -- Dyspnea / Dwayne A. Thomas & Warren R. Summer. -- Cough / Juzar Ali. -- Hemoptysis / Juzar Ali. -- Noncardiac chest pain / Kevin Reed & Warren R. Summer. -- Lung sounds / Ross S. Summer & Warren R. Summer. -- Disease/disorder based. -- Obstructive lung disease / David A. Welsh & Dwayne A. Thomas. -- Parenchymal lung disease / Leonardo Seoane & Carol M. Mason. -- Pulmonary vascular disease / Bennet P. deBoisblanc. -- Occupational/inhalational/environmental disease / Judd Shellito. -- Respiratory infections / Carol M. Mason & Warren R. Summer. -- Diseases of the pleura / Roy Culotta & David Taylor. -- Respiratory abnormalities with sleep disorders / Caroline Barton. -- Respiratory failure / Peter DeBlieux. -- Lung under stress / Stephen P. Kantrow. -- Pediatric lung disorders / Bonnie Desselle.
  • Pulmonary physiology. 7th ed. Lane Catalog record
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  • 1. Function & structure of the respiratory system -- 2. Mechanics of breathing -- 3. Alveolar ventilation -- 4. Blood flow to the lung -- 5. Ventilation-perfusion relationships -- 6. Diffusion of gases and interpretation of pulmonary function tests -- 7. Transport of oxygen & carbon dioxide in the blood -- 8. Acid-base balance -- 9. Control of breathing -- 10. Nonrespiratory functions of the lung -- 11. The Respiratory system under stress.
  • Normal pregnancy -- Physiological transition from fetal to neonatal life in pregnancy -- Respiratory physiology in pregnancy -- High altitude, chronic hypoxia, and pregnancy -- Sleep physiology in pregnancy -- General management principles in pregnancy -- Diagnostic imaging in pregnancy -- Prescribing in pregnancy and lactation -- Monitoring fetal well-being in the critical care setting -- Anesthetic considerations in pregnant patients with pulmonary disorders -- Pulmonary disorders in pregnancy -- Obstructive sleep apnea in pregnancy -- Restless legs syndrome and periodic limb movement disorder in pregnancy -- Asthma in pregnancy -- Tuberculosis and pregnancy -- Pneumonia in the pregnant patient -- Chronic pulmonary disease and pregnancy -- Neuromuscular and chest wall diseases in pregnancy -- Pregnancy and the cystic fibrosis patient -- Pulmonary complications of collagen vascular disease in pregnancy -- Venous thromboembolism in pregnancy -- Pulmonary arterial hypertension in pregnancy -- Pulmonary procedures during pregnancy -- Critical illness in pregnancy -- Acute lung injury in pregnancy -- Airway management and mechanical ventilation in pregnancy.
  • Pulmonary Sarcoidosis: A Guide for the Practicing Clinician is a valuable resource for clinicians of varied disciplines concerning the care of the sarcoidosis patient. Sarcoidosis is a multi-system disorder and represents a major challenge to physicians. Although any organ may be involved with sarcoidosis, the lung is the most common organ affected. Chapters are written by distinguished authors who have extensive experience in caring for these patients. Detailed figures and tables are provided to guide the practicing clinician through all aspects of the condition, from clinical manifestations to treatment options. Pulmonary Sarcoidosis: A Guide for the Practicing Clinician is fully comprehensive and evidence-based and will be an essential addition to the bookshelves of all whose practice involves the care and treatment of patients with sarcoidosis.
  • Pulmonary vascular disease Lane Catalog record
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  • Updated clinical classification of pulmonary hypertension -- Pathology of pulmonary arterial hypertension -- Invasive rest and exercise hemodynamics in the modern management of pulmonary vascular disease: an expanding role in the future -- Exercise testing in pulmonary arterial hypertension -- Noninvasive exploration of the pulmonary circulation and the right heart -- Biomarkers in pulmonary arterial hypertension -- Genetics of pulmonary arterial hypertension and the concept of heritable pulmonary arterial hypertension -- Drug- and toxin-induced pulmonary arterial hypertension -- Idiopathic pulmonary arterial hypertension and its prognosis in the modern management era in developed and developing countries -- Pulmonary arterial hypertension complicating connective tissue disorders -- Pulmonary arterial hypertension and HIV and other viral infections -- Portopulmonary hypertension and hepatopulmonary syndrome -- Pulmonary hypertension in congenital heart diseases -- Pulmonary hypertension in sickle cell disease -- Schistosomiasis and pulmonary hypertension -- Pulmonary veno-occlusive disease -- Pulmonary hypertension and left heart disease -- Pulmonary hypertension in chronic obstructive pulmonary disease -- Pulmonary hypertension complicating interstitial and granulomatous lung diseases -- High-altitude pulmonary hypertension -- Acute pulmonary venous thromboembolic disease -- Anticaogulation for venous thromboembolism in the modern management era -- Chronic thromboembolic pulmonary hypertension -- Medical treatment of pulmonary arterial hypertension -- Lung transplantation and role for novel extracorporeal support in pulmonary hypertension -- Artrial septostomy -- Pulmonary vascular disorders in hereditary hemorrhagic telangiectasia -- Future perspectives in pulmonary arterial hypertension.
  • Introduction -- Mean Arterial Pressure -- Pulse Pressure -- Evaluation of the Mechanical Properties of Large Arteries -- Central Arterial Blood Pressure -- Pulse Wave Analysis -- Central Blood Pressure and Cardiovascular Risk -- Noninvasive Measurement of Central Blood Pressure -- Instruments for Pulse Wave Analysis and Measurement of Pulse Wave Velocity -- Pulse Wave Velocity and Pulse Wave Analysis in Experimental Animals.
  • Nucleotide release by airway epithelia / E.R. Lazarowski ... [et al.] -- Mechanisms regulating airway nucleotides / M. Picher -- Computational model for the regulation of extracellular ATP and adenosine in airway epithelia / G.J. Garcia ... [et al.] -- Regulation of airway nucleotides in chronic lung diseases / C.R. Esther, Jr., N.E. Alexis and M. Picher -- Nucleotide-mediated airway clearance / A. Schmid ... [et al.] -- Purinergic signaling in wound healing and airway remodeling / A. van der Vliet and P.F. Bove -- Purinergic regulation of airway inflammation / M. Koeppen ... [et al.] -- Animal models of airway diseases / L.F. Thompson, M. Picher and M.R. Blackburn -- Therapeutic applications / S. Tilley, J. Volmer and M. Picher.
  • Introduction -- Early History of Purinergic Signalling -- Purinergic Cotransmission -- Mechanisms of ATP Release and Inactivation -- Receptors for Purines and Pyrimidines -- Evolution of Purinergic Signalling -- Peripheral Nervous System -- Purinergic Signalling in the Central Nervous System -- Sensory Nerves -- Special Senses -- Ontogeny of Purinergic Neurotransmission.
  • Demonstrates a wealth of new procedures and provides fresh approaches from new leading authorities representing the various aesthetic specialties, including from plastic surgery, oculoplastic surgery, and dermatology, and new illustrations that help to update and enhance operative skills. A a new bonus DVD includes intraoperative videos that demonstrates how to perform a variety of key techniques, step by step.
  • "The Putting Patients First Field Guide: Global Lessons in Designing and Implementing Patient Centered Care is the ultimate real-world guide to how hospitals, long-term care communities and integrated health care systems around the world are operationalizing the fundamental dimensions of a patient-centered culture, including access to information, family involvement, healing environments, employee and physician engagement, patient advocacy and more. Edited by Susan Framption and Patrick Charmel of Planetree, a nonprofit consulting and research organization dedicated to patient centered care, the book represents a concrete pathway to patient-centered excellence, using lessons from organizations around the world. By featuring real life examples of providers from nearly every continent, this book will underscore the adaptability of a patient-centered approach to accommodate cultural nuances while addressing the universal desire for patients and family members across cultures for holistic health care experiences that promote humanity, partnership and transparency."-- Provided by publisher.
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  • The challenges of implementing evidence-based practice guidelines in clinical settings have been widely recognized in the health care field. This implementation guide is designed as a "how-to" resource for managers and clinicians in the Military Health System who seek practical techniques to help them integrate evidence-based practice guidelines into the medical care processes at their medical treatment facilities (MTFs). The guide will be of particular use because its content is based on both published research on clinical guideline implementation and more than two years of experience with guideline implementation during the Army Medical Department/RAND Guideline Implementation project. In this project, three regional demonstrations tested methods for implementing three different guidelines, with the participation of eleven Army MTFs. Lessons learned from the project have been incorporated into the information provided in this guide as well as in field note examples highlighted throughout the document.
  • Orofacial pain : a challenge and chance (not only) for dentistry / Turp, J.C., Hugger, A., Sommer, C. -- Characteristics of muscle nociception / Mense, S. -- Nociceptors of the joint with particular reference to silent nociceptors / Schaible, H.-G. -- Inflammatory mediators in temporomandibular joint pain / Kopp, S., Sommer, C. -- The role of reproductive hormones in orofacial pain / LeResche, L. -- Pathophysiology of orofacial pain / Sessle, B. -- Dental pain : pathophysiology and management / Khan, A.A., Hargreaves, K.M. -- Myofascial temporomandibular disorder pain : pathophysiology and management / Schindler, H.J., Svensson, P. -- Painful arthrogenous temporomandibular disorders : pathophysiology, diagnosis, management and prognosis / Steenks, M.H., Hugger, A., de Wijer, A. -- Neuralgic and idiopathic facial pain : pathophysiology and management / Sommer, C. -- Burning mouth syndrome : pathophysiology and management / Zakrzewska, J., Renton, T. -- Psychosocial impact of orofacial Pain / Dworkin, S.F. -- A rationale for the classification of orofacial pain / Woda, A. -- Orofacial pain: past and future / Greene, C.S. -- The end of an era: orofacial pain enters the genomic age : implications and opportunities for research and the care of patients / Stohler, C.S.
  • Pyrosequencing protocols 2006, Springer Protocols
    The history of pyrosequencing / Pol Nyron -- Pyrosequencing applications / Sharon Marsh -- Web-based primer design software for genome-scale genotyping by pyrosequencing / Steven Ringquist ... [et al.] -- Pyrosequencing : a simple method for accurate genotyping / Cristi R. King and Tiffany Scott-Horton -- Universal primer applications for pyrosequencing / Dong-Chuan Guo and Dianna M. Milewicz -- Allele quantification and DNA pooling methods / Jonathon Wasson -- Multiplex pyrosequencing for DNA variation analysis / Pritesh Patel, Yih-Horng Shiao, and Paolo Fortina -- Analysis of gene-specific DNA methylation patterns by the pyrosequencing technology / Jørg Tost and Ivo Glynne Gut -- Detecting mutations that confer oxazolidinone resistance in gram-positive bacteria / Neil Woodford, Sarah E. North, and Matthew J. Ellington -- Pyrosequencing-based strategies for improved allele typing of HLA loci / Steven Ringquist ... [et al.] -- Pyrosequencing of phage display libraries for the identification of cell-specific targeting ligands / Ahad A. Rahim -- Gene copy number detection in animal studies / Gerli Pielberg and Leif Andersson -- Detection of allelic imbalance in gene expression using pyrosequencing / Hua Wang and Steven C. Elbein -- Pyrosequencing genotype storage techniques / Derek J. Van Booven.
  • Python cookbook. 2nd ed. 2005, ProQuest Safari
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  • Python for bioinformatics 2010, CRCnetBASE
    I. PROGRAMMING. 1. Introduction -- 2. First Steps with Python -- 3. Basic Programming: Data Types -- 4. Programming: Flow Control -- 5. Dealing with Files -- 6. Code Modularizing -- 7. Error Handling -- 8. Introduction to Object Orienting Programming (OOP) -- 9. Regular Expressions --- II. BIOPYTHON. 10. Introduction to Biopython --- III. ADVANCED TOPICS. 11. Web Applications -- 12. XML -- 13. Python and Databases -- 14. Collaborative Development: Version Control --- IV. PYTHON RECIPES WITH COMMENTED SOURCE CODE. 15. Sequence Manipulation in Batch -- 16. Web Application for Filtering Vector Contamination -- 17. Searching for PCR Primers Using Primer3 -- 18. Calculating Melting Temperature from a Set of Primers -- 19. Filtering out Specific Fields from a Genbank File -- 20. Converting XML Blast File into HTML -- 21. Inferring Splicing Sites -- 22. DNA Mutations with Restrictions -- 23. Web Server for Multiple Alignment -- 24. Drawing Marker Positions Using Data Stored in a Database --- Appendixes. A. Python and Biopython Installation -- B. Selected Papers -- C. Included DVD: Virtual Machine Installation and Use -- D. Python Language Reference -- E. Answers to Odd-Numbered Questions -- F. Python Style Guide.
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  • Python pocket reference ProQuest Safari

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Largest, broadest eBook package; covers all sciences, as well as technology (including software), medicine, and humanities. In addition to covering Wiley and Springer, MyiLibrary is also the only provider for Oxford and Cambridge University Press titles. No seat restrictions.Largest, broadest eBook package; covers all sciences, as well as technology (including software), medicine, and humanities. In addition to covering Wiley and Springer, MyiLibrary is also the only provider for Oxford and Cambridge University Press titles. No seat restrictions.Large number of high quality software and database programming titles from O'Reilly. Other software titles are also available from Sams and Prentice Hall. Limited to 7 concurrent users.Vast collection of software and database programming titles from multiple publishers, including Microsoft Press.Largest provider of engineering-related eBooks; includes titles in computer science and biomedical engineering.Over 4,000 full-text e-books covering scientific and technical information from CRC Press and others. Many handbooks and single volume reference sources.A repository of medical knowledge from internal medicine, cardiology, genetics, pharmacy, diagnosis and management, basic sciences, patient care, and more. Continuously expanding, all databases in the repository contain the latest editions of selected medical titles.Includes peer-reviewed life science and biomedical research protocols compiled from Methods in Molecular Biology, Methods in Molecular Medicine, Methods in Biotechnology, Methods in Pharmacology and Toxicology, Neuromethods, the Biomethods Handbook, the Proteomics Handbook, and Springer Laboratory Manuals.Contains full text access to selected biomedical and nursing books.Provides one-click access to important clinical resources; includes evidence-based diagnosis and treatment guidelines, Books, EBM articles, Ovid MEDLINE, Drug facts and comparisons, Drug interaction facts, guidelines from National Guideline Clearinghouse, patient handouts (English and Spanish), and local content.ClinicalKey provides access to textbooks, electronic journals, practice guidelines, drug information, and patient education handouts.A collection of biomedical books that can be searched directly by concept, and linked to terms in PubMed abstracts.Provides online, full-text access to Springer's journal titles as well as journals from other publishers. Subjects include: life sciences, chemical sciences, environmental sciences, geosciences, computer science, mathematics, medicine, physics and astronomy, engineering and economics. Also includes eBooks.Collection of over 8 thousand fulltext titles in engineering, math, and basic and applied biomedical research. Coverage is from 1967 to the present.A library of ebooks on a wide array of topics, digitized and made available online in conjunction with the original publishers.