Books

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  • 2014 ScienceDirect
    Ira J. Kalet, Ph.D.
    This second edition of a pioneering technical work in biomedical informatics provides a very readable treatment of the deep computational ideas at the foundation of the field. Principles of Biomedical Informatics, 2nd Edition is radically reorganized to make it especially useable as a textbook for courses that move beyond the standard introductory material. It includes exercises at the end of each chapter, ideas for student projects, and a number of new topics, such as: .tree structured data, interval trees, and time-oriented medical data and their use . On Line Application Processing (OLAP), an old database idea that is only recently coming of age and finding surprising importance in biomedical informatics a discussion of nursing knowledge and an example of encoding nursing advice in a rule-based system X-ray physics and algorithms for cross-sectional medical image reconstruction, recognizing that this area was one of the most central to the origin of biomedical computing .an introduction to Markov processes, and an outline of the elements of a hospital IT security program, focusing on fundamental ideas rather than specifics of system vulnerabilities or specific technologies. It is simultaneously a unified description of the core research concept areas of biomedical data and knowledge representation, biomedical information access, biomedical decision-making, and information and technology use in biomedical contexts, and a pre-eminent teaching reference for the growing number of healthcare and computing professionals embracing computation in health-related fields. As in the first edition, it includes many worked example programs in Common LISP, the most powerful and accessible modern language for advanced biomedical concept representation and manipulation. The text also includes humor, history, and anecdotal material to balance the mathematically and computationally intensive development in many of the topic areas. The emphasis, as in the first edition, is on ideas and methods that are likely to be of lasting value, not just the popular topics of the day. Ira Kalet is Professor Emeritus of Radiation Oncology, and of Biomedical Informatics and Medical Education, at the University of Washington. Until retiring in 2011 he was also an Adjunct Professor in Computer Science and Engineering, and Biological Structure. From 2005 to 2010 he served as IT Security Director for the University of Washington School of Medicine and its major teaching hospitals. He has been a member of the American Medical Informatics Association since 1990, and an elected Fellow of the American College of Medical Informatics since 2011. His research interests include simulation systems for design of radiation treatment for cancer, software development methodology, and artificial intelligence applications to medicine, particularly expert systems, ontologies and modeling.
  • 2002 ScienceDirect
    edited by John P. Bilezikian, Lawrence G. Raisz, Gideon A. Rodan.
    v. 1.-- Part. I. Basic principles -- v. 2.-- Part. II. Molecular mechanisims of metabolic bone diseases -- Part. III. Pharmacological mechanisms of therapeutics -- Part. IV. Methods in bone research.
  • 2012 Springer
    Jona J. Sela, Itai A. Bab, editors.
    Part 1. Physiology of Bone Healing / Cellular and Molecular Aspects of Bone Repair / Itai A. Bab and Jona J. Sela -- Primary Mineralization / Jona J. Sela -- Healing of Bone Fracture: General Concepts / Jona J. Sela and Itai A. Bab -- Part 2. Systemic Factors in Bone Healing / Anabolic Agents in Bone Repair / Itai A. Bab -- Bone Repair in Diabetes / Gail Amir -- Cannabinoids in Bone Repair / Itai A. Bab -- Part 3. Bridging of Skeletal Defects and Implants / Mesenchymal Stem Cells for Bone Gene Therapy / Gadi Pelled, Olga Mizrahi, Nadav Kimelman-Bleich and Dan Gazit -- Scaffolds in Skeletal Repair / Erella Livne and Samer Srouji -- Bone Reaction to Implants / David Kohavi.
  • 2009 Springer
    edited by Robert K. Oldham, Robert O. Dillman.
    Cancer biotherapy : general principles / Robert K. Oldham -- The pathogenesis of cancer metastasis : relevance to therapy / Sun-Jin Kim ... [et al.] -- Developmental therapeutics and the design of clinical trials / Robert K. Oldham -- Recombinant proteins and gnomics in cancer therapy / Kapil Mehta ... [et al.] -- Current concepts in immunology / Robert K. Oldham -- Therapeutic approaches to cancer-associated immune suppression / Robert K. Oldham -- Cancer vaccines / Kenneth A. Foon and Malek M. Safa -- Cytokines / Walter M. Lewko and Robert K. Oldham -- Interferons : therapy for cancer / David Goldstein ... [et al.] -- Monoclonal antibody therapy / Robert O. Dillman -- Immunotoxins / Arthur E. Frankel, Jung-Hee Woo, and David M. Neville -- Drug immunoconjugates / Malek Safa, Kenneth A. Foon, and Robert K. Oldham -- Targeted radionuclide therpy of cancer / John M. Pagel ... [et al.] -- Stem cell/bone marrow transplantation as biotherapy / Robert K. Oldham -- Cellular immunotherapy (CI), where have we been and where are we going? / John R.Yanelli -- Growth and differentiation factors as cancer therapeutics / Kapil Mehta, Robert K. Oldham, and Bulent Ozpolat -- Granulocyte colony-stimulating factor : biology and clinical potential / MaryAnn Foote and George Morstyn -- Granulocyte-macrophage colony-stimulating factor / MaryAnn Foote and George Morstyn -- Cancer gene therapy / Donald J. Buchsbaum ... [et al.] -- Regulatory process for approval of biologicals for cancer therapy / Antonio J. Grillo-López -- Cancer biotherapy : 2009 disease-related activity / Robert K. Oldham and Robert O. Dillman -- Biological therapy of melanoma / Robert K. Oldham -- Biological therapy of genitourinary cancer / Robert K. Oldham -- Biological therapy of colon cancer / Robert O. Dillman -- Biological therapy of breast cancer / Robert O. Dillman -- Biological therapy of lung cancer / Robert O. Dillman -- Biological therapy of B and T cell lymphoproliferative disorders / Robert O. Dillman -- Biological therapy of multiple myeloma / Robert K. Oldham -- Biological therapy of squamous cell cancers of the head and neck / Robert O. Dillman -- Biological therapy of glioblastoma / Robert O. Dillman -- Speculations for 2009 and beyond / Robert K. Oldham.
  • 2008 Springer
    Fred Bunz.
  • 2008 Springer
    edited by Charles E. Butler, Neil A. Fine.
    Plastic surgery: a component in the comprehensive care of cancer patients -- The principles of cancer reconstruction -- Breast reconstruction: timing and coordination with adjuvant therapy -- Breast reconstruction: autogenous tissue -- Breast reconstruction: implant and nipple reconstruction -- Skin cancer and reconstruction -- Lip, cheek, and scalp reconstruction -- Reconstruction of mandible, maxilla, and skull base -- Pharynx, cervical esophagus, and oral cavity reconstruction -- Concepts in nasal reconstruction -- Extremity reconstruction -- Abdominal wall tumors and their reconstruction -- Reconstruction of the intra-abdominal pelvis and the perineum -- Management of chemotherapeutic agent extravasation and radiation therapy adverse effects.
  • 2015 ClinicalKey
    Stuart J. Hutchison, MD, FRCP(C), FACC, FAHA, FSCCT, Clinical Professor of Medicine, Departments of Cardiac Sciences, Medicine, and Radiology, University of Calgary, Director of Echocardiography, Foothills Medicine Centre and Libin Cardiovascular Institute, Calgary, Alberta, Canada, Naeem Merchant, MD, FRCP(C), Clinical Professor of Medicine, Departments of Cardiac Services, Medicine, and Radiology, University of Calgary, Calgary, Alberta, Canada.
  • 2012 ClinicalKey
    Stuart J. Hutchison.
    First things first -- The frontal CXR -- The lateral CXR -- Heart size assessment -- Pulmonary vasculature and pulmonary embolism -- Heart failure -- The thoracic aorta -- Localizing prosthetic valves -- Mechanical prosthetic valves -- Bio-prosthetic valves -- Annuloplasty rings -- Prosthetic valve dysfunction -- Aortic stents and percutaneous aortic valves -- Radiographic findings by diagnosis : cardiomyopathies -- Radiographic findings by diagnosis : valve cardiovascular disease -- Radiographic findings by diagnosis : pericardial diseases -- Radiographic findings by diagnosis : CAD- complications of infarction -- Radiographic findings by diagnosis : congenital- situs and shunts -- Radiographic findings by diagnosis : congenital abnormalities- pulmonary stenosis -- Radiographic findings by diagnosis : complex congenital abnormalities -- Radiographic findings by diagnosis : other congenital abnormalities -- Central venous and pulmonary artery catheters -- Pacemakers and ICDs -- Percutaneous and surgically inserted ventricular assist devices -- Tubes & drains -- The ICU and post-op patient -- Cardiac & vascular calcification -- Cardiac and vascular trauma -- Clinical uses of the chest radiograph.
  • 2006 ScienceDirect
    edited by Michael R. King.
    Traction forces exerted by adherent cells / by Cynthia A. Reinhart-King and Daniel A. Hammer -- Control of endothelial cell adhesion by mechanotransmission from cytoskeleton to substrate / by Rosalind E. Mott and Brian P. Helmke -- Use of hydrodynamic shear stress to analyze cell adhesion / by David Boettiger -- Cellular tensegrity models and cell-substrate interactions / by Dimitrije Stamenović, Ning Wang, and Donald E. Ingber -- Bond formation during cell compression / by Elena Lomakina and Richard E. Waugh -- Dynamics of the neutrophil surface during emigration from blood / Thomas R. Gaborski and James L. McGrath -- Glycocalyx regulation of cell adhesion / Philippe Robert, Laurent Limozin, Anne-Marie Benoliel, Anne Pierres, and Pierre Bongrand -- Atomistic modeling of protein adsorption to ceramic biomaterials in water: a first step toward realistic simulation of the biomaterials surface in vivo / by Alan H. Goldstein -- Model cell membrane surfaces for measuring receptor-ligand interactions / by Craig D. Blanchette, Timothy V. Ratto, and Marjorie L. Longo -- A flow chamber for capillary networks: leukocyte adhesion in capillary sized, ligand-coated micropipettes / by David F.J. Tees, Prithu Sundd, and Douglas J. Goetz -- Adhesion of flowing neutrophils to model vessel surfaces: constraint and regulation by the local hemodynamic environment / Gerard B. Nash and G. Ed Rainger -- Hydrodynamic interactions between cells on reactive surfaces / Dooyoung Lee and Michael R. King -- Dynamics of platelet aggregation and adhesion to reactive surfaces under flow / Nipa A. Mody and Michael R. King.
  • 2007
    Harold P. Adams, Jr.
    Status: Not Checked OutLane Catalog Record
  • 2005 WHO
    Also available: Print – 2005
  • 2010 Springer
    edited by Daniel C. Chung and Daniel A. Haber.
    Basic Principles of Cancer Genetics / Leif W. Ellisen and Daniel A. Haber -- Principles of Cancer Genetic Counseling and Genetic Testing / Kristen M. Shannon and Devanshi Patel -- Genetics of Hereditary Breast Cancer / Paula D. Ryan -- Surgical Management of Hereditary Breast and Ovarian Cancer / Michelle C. Specht, Marcela G. del Carmen and Barbara L. Smith -- Hereditary Colon Cancer: Colonic Polyposis Syndromes / Andrew T. Chan and Daniel C. Chung -- Hereditary Colon Cancer: Lynch Syndrome / Eunice L. Kwak and Daniel C. Chung -- Hereditary Pancreatic Cancer / Janivette Alsina and Sarah P. Thayer -- Hereditary Diffuse Gastric Cancer / Prakash K. Pandalai and Sam S. Yoon -- Familial Renal Cell Cancers and Pheochromocytomas / Gayun Chan-Smutko and Othon Iliopoulos -- Familial Atypical Mole Melanoma (FAMM) Syndrome / Elizabeth D. Chao, Michele J. Gabree and Hensin Tsao -- Multiple Endocrine Neoplasia / Yariv J. Houvras and Gilbert H. Daniels -- Pediatric Malignancies: Retinoblastoma and Wilms' Tumor / David A. Sweetser and Eric F. Grabowski -- Neurofibromatosis and Schwannomatosis / Miriam J. Smith and Scott R. Plotkin -- The HapMap Project and Low-Penetrance Cancer Susceptibility Alleles / Edwin Choy and David Altshuler -- Somatic Genetic Alterations and Implications for Targeted Therapies in Cancer (GIST, CML, Lung Cancer) / Alice T. Shaw, Eyal C. Attar, Edwin Choy and Jeffrey Engelman.
  • 2013 Springer
    Steven L. Gersen and Martha B. Keagle, editors.
    Part I. Basic Concepts and Background. History of Clinical Cytogenetics / Steven L. Gersen -- DNA, Chromosomes, and Cell Division / Martha B. Keagle -- Human Chromosome Nomenclature: An Overview and Definition of Terms / Marilyn L. Slovak, Aaron Theisen, Lisa G. Shaffer -- Part II. Examining and Analyzing Chromosomes. Basic Cytogenetics Laboratory Procedures / Martha B. Keagle, Steven L. Gersen -- The Essentials of Light Microscopy / Nathan S. Claxton, Stephen T. Ross -- Quality Control and Quality Assurance / Martha B. Keagle -- Instrumentation in the Cytogenetics Laboratory / Steven L. Gersen -- Part III. Clinical Cytogenetics. Autosomal Aneuploidy / Jin-Chen C. Wang -- Structural Chromosome Rearrangements / Kathleen Kaiser-Rogers, Kathleen W. Rao -- Sex Chromosomes, Sex Chromosome Disorders, and Disorders of Sex Development / Cynthia M. Powell -- The Cytogenetics of Infertility / Linda Marie Randolph -- Prenatal Cytogenetics / Linda Marie Randolph -- The Cytogenetics of Spontaneous Abortion / Solveig M. V. Pflueger, -- Chromosome Instability / Xiao-Xiang Zhang, -- Part IV. Cancer Cytogenetics. The Cytogenetics of Hematologic Neoplasms / Aurelia Meloni-Ehrig -- The Cytogenetics of Solid Tumors / Linda D. Cooley, Kathleen S. Wilson -- Part V. Adjunct Technologies -- Fluorescence In Situ Hybridization (FISH) / Daynna J. Wolff -- Microarray-Based Cytogenetics / Lisa G. Shaffer -- Part VI. Beyond Chromosomes. Fragile X--A Family of Disorders: Changing Phenotype and Molecular Genetics / Elaine B. Spector -- Genomic Imprinting and Uniparental Disomy / Jin-Chen C. Wang -- Genetic Counseling / Sarah Hutchings Clark.
  • 2008
    edited by Tadataka Yamada ; associate editors, David H. Alpers ... [et al.].
    Status: Not Checked OutLane Catalog Record
  • 2008 Springer
    edited by Michael Barratt, Sam Pool.
  • 2014 ScienceDirect
    edited by Jose Cibelli [and six others].
    Principles of Cloning, Second Edition is the fully revised edition of the authoritative book on the science of cloning. The book presents the basic biological mechanisms of how cloning works and progresses to discuss current and potential applications in basic biology, agriculture, biotechnology, and medicine. Beginning with the history and theory behind cloning, the book goes on to examine methods of micromanipulation, nuclear transfer, genetic modification, and pregnancy and neonatal care of cloned animals. The cloning of various species-including mice, sheep, cattle, and non-mammals-is considered as well.
  • 2015 AccessSurgery
    2015 AccessMedicine
    editors, Jesse B. Hall, Gregory A. Schmidt, John P. Kress.
    An overview of the approach to and organization of critical care -- General mangement of the patient -- Cardiovascular disorders -- Pulmonary disorders -- Infectious disorders -- Neurologic disorders -- Hematalogic and oncologic disorders -- Renal and metabolic disorders -- Gastrointestinal disorders -- The surgical patient -- Special problems in critical care.
  • v.I-II=, 2016 Springer
    Alpesh Gandhi, Narendra Malhotra, Jaideep Malhotra, Nidhi Gupta, Neharika Malhotra Bora, editors.
  • 2013 Springer
    Reza Shaker...[et al.], editors.
    Principles of Deglutition is the first in class comprehensive multidisciplinary textbook to encompass the entire field of normal and disordered deglutition. It is designed as the definitive text for all those who desire to further their knowledge of the dynamic and expanding field of deglutology. The text is created to serve as a treasured reference for clinicians, educators and trainees from such diverse backgrounds as gastroenterology, speech language pathology, otolaryngology, rehabilitation medicine, radiology and others.Principles of Deglutition brings together the state-of-knowledge from 12 disciplines involved in dysphagia through contributions of over one hundred thought leaders and master clinicians for the benefit of patients and providers alike. It concisely organizes the wealth of knowledge that exists in each of the contributing disciplines into one comprehensive information platform. Principles of Deglutition provides a one-stop destination for members of all specialties to obtain state-of-the-art and critically reviewed information regarding deglutition physiology, pathophysiology, diagnosis and management. It delivers a comprehensive and in depth review of deglutition related cerebral cortical, brainstem, peripheral nerves, and neuromuscular mechanisms, advanced diagnostic modalities and standard of care and cutting edge medical, rehabilitative and surgical treatments. It is an essential reference for all deglutologists.
  • 2010 Springer
    Leonid Poretsky, editor.
    Part 1. The Main Events in the History of Diabetes Mellitus / Jacek Zajac, Anil Shrestha, Parini Patel and Leonid Poretsky -- Part 2. Physiology of glucose metabolism -- Normal Glucose Homeostasis / Muhammad Z. Shrayyef and John E. Gerich -- Endocrine Pancreas / Barry J. Brass, Zinoviy Abelev, Emilia Pauline Liao and Leonid Poretsky -- The Role of Incretins in Insulin Secretion / Brock E. Schroeder and Orville Kolterman -- Cellular Mechanisms of Insulin Action / Theodore P. Ciaraldi -- The Role of Brain in Glucose Metabolism / Silvana Obici and Paulo José Forcina Martins -- Part 3. Diagnosis and epidemiology of diabetes -- Diagnostic Criteria and Classification of Diabetes / James P. Leu and Joel Zonszein -- Epidemiology / Shadi Chamany and Bahman P. Tabaei -- Diabetes in Culturally Diverse Populations: From Biology to Culture / A. Enrique Caballero -- Part 4. Genes and diabetes -- Genetics of Type 2 Diabetes: From Candidate Genes to Genome-Wide Association Analysis / Kevin Brown and Alan R. Shuldiner -- Rodent Models of Diabetes / Ronald J. Christopher, Koji Takeuchi and Bumsup Lee -- Part 5. Diabetes Syndromes -- Type 1 Diabetes Mellitus: Epidemiology, Genetics, Pathogenesis, and Clinical Manifestations / Omar Ali -- Type 2 Diabetes Mellitus: Epidemiology, Genetics, Pathogenesis, and Clinical Manifestations / Vivian Fonseca and Jennifer John-Kalarickal -- Maturity-Onset Diabetes of the Young: Molecular Genetics, Clinical Manifestations, and Therapy / Markus Stoffel -- Diabetes in Pregnancy / Adina E. Schneider, Elliot J. Rayfield, Agustin Busta and Yuriy Gurevich -- Secondary Causes of Diabetes Mellitus / Yana B. Garger, Prajesh M. Joshi, Ashutosh S. Pareek, Carla M. Romero and Amit K. Seth, et al. -- Syndromes of Extreme Insulin Resistance / George Grunberger and Bianca Alfonso -- Part 6. Complications of diabetes -- Acute Hyperglycemic Syndromes: Diabetic Ketoacidosis and the Hyperosmolar State / Yun Feng and Adrienne M. Fleckman -- Hypoglycemia in Diabetes Mellitus / Mazen Alsahli and John E. Gerich -- Intake of Advanced Glycation Endproducts: Role in the Development of Diabetic Complications / Helen Vlassara and Gary E. Striker -- Diabetic Retinopathy / Ketan Laud and Uri Shabto -- Diabetic Nephropathy / James F. Winchester, Donald A. Feinfeld, Nikolas B. Harbord and Alan Dubrow -- Diabetic Neuropathy / Russell L. Chin and Michael Rubin -- Peripheral Vascular Disease in Diabetes / Jennifer K. Svahn, Jeffrey S. Kirk, Omar H. Llaguna and Nancy Habib -- The Diabetic Foot / Dennis Shavelson, John S. Steinberg and Bradley W. Bakotic -- Male Sexual Dysfunction in Diabetes Mellitus / Barry M. Mason, Albert C. Leung, Michael E. DiSanto and Arnold Melman -- Gastrointestinal Manifestations of Diabetes / Donald P. Kotler and Stanley Hsu -- Dyslipidemia: Pathogenesis and Management / Om P. Ganda -- Dermatological Complications of Diabetes Mellitus; Allergy to Insulin and Oral Agents / George I. Varghese, Ellen S. Marmur and Mathew C. Varghese -- Part 7. Related disorders -- Obesity - Genetics, Pathogenesis, Therapy / William C. Hsu, Kalliopi M. Arampatzi and Christos S. Mantzoros -- Hypertension / Samy I. McFarlane, Ho Won Lee, Sara Choudhry and Nathaniel Winer -- Coronary Artery Disease and Cardiomyopathy / Richard B. Devereux -- Polycystic Ovary Syndrome / Susan B. Zweig, Marsha C. Tolentino, Marina Strizhevsky and Leonid Poretsky -- Insulin Resistance and the Metabolic Syndrome / Mary Ann Banerji and Rochelle L. Chaiken -- Diabetes and Liver Disease / Douglas F. Meyer and Henry C. Bodenheimer -- The Increased Risk of Cancer in Obesity and Type 2 Diabetes: Potential Mechanisms / Emily Jane Gallagher, Ruslan Novosyadlyy, Shoshana Yakar and Derek LeRoith -- Diabetes and Sleep Disorders / Abhijith Hegde and Steve H. Salzman -- HIV Infection and Diabetes / Madhu N. Rao, Kathleen Mulligan and Morris Schambelan -- Part 8. Therapy of diabetes mellitus-general principles -- Glycemic Goals / David J. Brillon -- Behavioral and Educational Approaches to Diabetes Self-Management / Maria A. Mendoza, Monique Welbeck and Grishma Parikh -- Dietary Therapy of Diabetes Mellitus / Gladys Witt Strain, Rosalia Doyle and Faith Ebel -- Exercise in the Therapy of Diabetes Mellitus / Sefton Vergano, Rajiv Bhambri and Stephen H. Schneider -- Therapy of Type 1 Diabetes Mellitus / Pejman Cohan and Anne L. Peters -- Treating Type 2 Diabetes Mellitus / Susan Herzlinger and Martin J. Abrahamson -- Prevention of Microvascular Complications of Diabetes - General Overview / Vincent Yen -- Psychiatric Care of the Patient with Diabetes / Jennifer L. Kraker and Stephen J. Ferrando -- Management of Diabetes and Hyperglycemia in the Hospital Setting / Samantha DeMauro-Jablonski and Silvio E. Inzucchi -- The Future of Diabetes Therapy / Graham T. McMahon -- Part 9. Diabetes prevention -- Prevention of Type 1 Diabetes Mellitus / Paolo Pozzilli and Chiara Guglielmi -- Prevention of Type 2 Diabetes Mellitus / Edward S. Horton -- Part 10. Resources for Patients with Diabetes / Marina Krymskaya.
  • 2008
    edited by Michael V. Johnston, Robert A. Gross.
    Status: Not Checked OutLane Catalog Record
  • 2012 ClinicalKey
    Stuart J. Hutchison.
    The Aortic Valve -- Aortic Stenosis -- Aortic Insufficiency -- The Mitral Valve -- Mitral Stenosis -- Mitral Insufficiency -- Tricuspid and Pulmonic Valve Disease -- Prosthetic Valves -- Infective Endocarditis -- Echocardiographic Assessment of the Left Ventricle -- Coronary Artery Disease : Ischemia, Infarction, and Complications -- Coronary Artery Disease : Stress Echocardiography -- Cardiomyopathies -- Diastolic Dysfunction and Echocardiographic Hemodynamics -- Contrast Echocardiography -- Proximal Isovelocity Surface Area and Flow Convergence Methods -- Echocardiography and Its Role in Cardiac Resynchronization Therapy -- Stress, Strain, Speckle, and Tissue Doppler Imaging : Practical Applications -- Stress, Strain, Speckle, and Tissue Doppler Imaging : Practical Applications -- Role of Transesophageal Echocardiography in Mitral Valve Repair -- Intracardiac Echocardiography -- Pericardial Diseases -- Right Heart Diseases -- Cardiac Masses -- Cardiac Trauma -- Echocardiographic Guidance of Procedures.
  • 2012 Springer
    Stephen Goundrey-Smith.
    Philosophical and Social Framework of Electronic Medicines Management -- History and Context of Electronic Prescribing in the US and UK -- Organization Benefits of Electronic Prescribing -- EP Systems as a Risk Management Tool -- Data Support for Electronic Medicines Management -- Electronic Medicines Management: Support for Professional Practice -- Electronic Medicines Management and Non-medical Prescribing -- Electronic Prescribing and Future Priorities.
  • 2008 Springer
    Stephen Goundrey-Smith.
  • 2013 Springer
    Jeffrey M. Marks, Brian J. Dunkin, editors.
    Written entirely by surgical endoscopists, Principles of Flexible Endoscopy for Surgeons presents a comprehensive overview of past, present, and future flexible gastrointestinal endoscopic techniques, with a focus on educating surgeons who may or may not already have the skills to perform flexible endoscopy. In addition to the endoscopic management of surgical issues, the volume describes the role of surgery in the management of endoscopic complications. Basic as well as advanced flexible endoscopic techniques are presented in both a didactic and visual mode, with representative endoscopic images and video clips. Recent endoscopic advancements which are not routinely a core component of surgical training programs are also covered in detail. Extensively illustrated with endoscopic images and accompanied by a DVD, Principles of Flexible Endoscopy for Surgeons is a valuable resource for surgeons on all facets of flexible endoscopy.
  • 2006
    Joseph R. Lakowicz.
    Status: Not Checked OutLane Catalog Record
    Introduction to fluorescence -- Instrumentation for fluorescence spectroscopy -- Fluorophores -- Time-domain lifetime measurements -- Frequency-domain lifetime measurements -- Solvent and environmental effects -- Dynamics of solvent and spectral relaxation -- Quenching of fluorescence -- Mechanisms and dynamics of fluorescence quenching -- Fluorescence anisotropy -- Time-dependent anisotropy decays -- Advanced anisotropy concepts -- Energy transfer -- Time-resolved energy transfer and conformational distributions of biopolymers -- Energy transfer to multiple acceptors in one, two, or three dimensions -- Protein fluorescence -- Time-resolved protein fluorescence -- Multiphoton excitation and microscopy -- Fluorescence sensing -- Novel fluorophores -- DNA technology -- Fluorescence-lifetime imaging microscopy -- Single-molecule detection -- Fluorescence correlation spectroscopy -- Radiative decay engineering : metal-enhanced fluorescence -- Radiative decay engineering : surface plasmon-coupled emission -- Appendix I. Corrected emission spectra -- Appendix II. Fluorescent lifetime standards -- Appendix III. Additional reading -- Answers to problems.
  • 2010 ScienceDirect
    2010 ClinicalKey
    edited by Marianne J. Legato ; section editors, William Byne ... [et al.].
    Chapter 1. The Effects of Gender in Neonatal Medicine / Tove S. Rosen, David Bateman -- Chapter 2. Sexual Development, Growth, and Puberty in Children / Gaya S. Aranoff, Jennifer J. Bell -- Chapter 3. Gender Differences in Pediatric Pulmonary Disease / Beverley J. Sheares -- Chapter 4. Gender-Specific Aspects of Pediatric Hematology and Oncology / James H. Garvin Jr. -- Chapter 5. Gender Differences in Neurological Conditions of Children / David M. Kaufman -- Chapter 6. Gender and Sports: Past, Present, and Future / Jordan D. Metzl -- Chapter 7. Gender Differences in the Functional Organization of the Brain / Ruben C. Gur, Tamara Bockow, Raquel E. Gur -- Chapter 8. Sexual Differentiation of Brain Structure and Function / Margaret M. McCarthy -- Chapter 9. The Sexed and Gendered Brain / William Byne -- Chapter 10. Age and Gender-Specific Patterns of Neurologic Illness / Joan Amatniek, Karin Sorra, Lauren Frey, W. Allen Hauser -- Chapter 11. Gender Differences in Stroke / Rebecca F. Gottesman, Argye E. Hillis -- Chapter 12. Gender Differences in Disorders that Present to Psychiatry / Mary V. Seeman -- Chapter 13. Hormone Replacement Therapy and Cognitive Function / Mary Sano, Diane Jacobs, Katya Gaynor -- Chapter 14. Gender and the Heart: Sex-Specific Differences in the Normal Myocardial Anatomy and Physiology / Marianne J. Legato, Jaswinder K. Leghe -- Chapter 15. Gender-Specific Aspects of Selected Coronary Heart Disease Risk Factors: A Summary of the Epidemiologic Evidence / Shari S. Bassuk, JoAnn E. Manson -- Chapter 16. Dyslipidemia Management in Women and Men: Exploring Potential Gender Differences / Kavita Sharma, Christian D. Nagy, Roger S. Blumenthal -- Chapter 17. Gender Differences in the Role of Stress and Emotion in Cardiovascular Function and Disease / David E. Anderson, Margaret A. Chesney -- Chapter 18. The Role of Sex and Gender in Cardiothoracic Surgery / Sandhya K. Balaram, Justin D. Blasberg -- Chapter 19. Gender Differences in Asthma / Robert H. Lim, Lester Kobzik -- Chapter 20. Gender Issues in Venous Thromboembolism / Susan Murin, Kathryn Bilello, Lisa Moores, Aaron Holley -- Chapter 21. Sleep in Women: Gender Differences in Health and Disease / Shirin Shafazand -- Chapter 22. Are Women More Susceptible to Chronic Obstructive Pulmonary Disease? / Kenneth R. Chapman -- Chapter 23. The Gender-Specific Aspects of Lung Cancer / Rebecca L. Toonkel, Charles A. Powell -- Chapter 24. Gender-Specific Considerations in Pulmonary Hypertension / Deborah Shure -- Chapter 25. Sex and Gender Differences in Pulmonary Manifestations of Autoimmune Disease / Muddassir Aliniazee, Marilyn K. Glassberg -- Chapter 26. Benign Metastasizing Leiomyoma and Lymphangioleiomyomatosis: Lung Diseases of Women / Muddassir Aliniazee, Marilyn K. Glassberg -- Chapter 27. Gender Differences in Susceptibility, Outcomes, and Pathophysiology of Sepsis / Kristy A. Bauman, MeiLan K. Han -- Chapter 28. Inflammatory Bowel Disease in Women / Melissa Munsell, Marc Sonenshine, Mary L. Harris -- Chapter 29. Disorders of Defecation in Women / Susan L. Gearhart -- Chapter 30. Idiopathic Gastroparesis: Gender Aspects / Henry P. Parkman -- Chapter 31. Liver Disease in Women / Karen Krok, Ayman Koteish -- Chapter 32. Gender Differences in Irritable Bowel Syndrome / Octavia Pickett-Blakely, Linda A. Lee, Gerald Mullin -- Chapter 33. Contraception / Karen Feisullin, Carolyn Westhoff -- Chapter 34. Infertility: The Male / Howard H. Kim, Peter N. Schlegel, Marc Goldstein -- Chapter 35. Infertility and In Vitro Fertilization / Elizabeth Barbieri, Sonya Kashyap, Pak H. Chung -- Chapter 36. Female Sexual Health / Barbara D. Bartlik, Julie A. Kolzet, Nazia Ahmad, Tahmina Parveen, Sarah Alvi -- Chapter 37. Male Sexual Dysfunction / Serkan Deveci, John P. Mulhall -- Chapter 38. Pelvic Pain: Urogenital Female Disorders / Andrew T. Goldstein, Lara J. Burrows -- Chapter 39. Lower Urogenital Tract Dysfunction in Men and Women / Doreen E. Chung, Alexis E. Te, Renuka Tyagi -- Chapter 40. Aging and the Lower Urogenital System / Catherine E. DuBeau -- Chapter 41. Menopause / Gloria Bachmann, Nora J. Doty -- Chapter 42. The Differences between Male and Female Breast Cancer / Coral Omene, Amy Tiersten -- Chapter 43. Difference in Germ Cell Tumors of the Reproductive Tract in Men and Women / Nicole LaNatra, Amy Tiersten -- Chapter 44. Gender Differences in Hereditary Cancer Syndromes: Risks, Management, and Testing for Inherited Predisposition to Cancer / Wendy K. Chung -- Chapter 45. Gender Differences in Emerging Infectious Diseases / Sharon Lewin -- Chapter 46. Sexually Transmitted Infections in Men and Women / Anne M. Rompalo, Khalil G. Ghanem -- Chapter 47. Infections in Pregnancy / Emilia Mia Sordillo, Bruce Polsky -- Chapter 48. Adult Immunization in Women and Men / Sally L. Hodder, Debra Chew, Shobha Swaminathan -- Chapter 49. Gender Differences in Autoimmune Diseases: Immune Mechanisms and Clinical Applications / Nabih I. Abdou, Virginia Rider -- Chapter 50. Hormones and Cytokines: Gender-Specific Effects / Maurizio Cutolo -- Chapter 51. Prolactin and Autoimmunity / Sara E. Walker -- Chapter 52. Sex Hormones and Immune Function / Robert G. Lahita -- Chapter 53. Pregnancy and Autoimmune Rheumatic Disease / Carl A. Laskin, Christine A. Clark, Karen A. Spitzer -- Chapter 54. Oral Contraceptives and Autoimmune Diseases / Taraneh Mehrani, Michelle Petri -- Chapter 55. Gender-Specific Issues in Organ Transplantation / Hilary Sanfey Chapter 56. Endogenous Sex Hormones and Risk of Type 2 Diabetes Mellitus in Men and Women / Sherita Hill Golden -- Chapter 57. Thyroid Disorders and Pregnancy / Matthew Kim -- Chapter 58. Sexual Function and Dysfunction in Men and Women / Karen Elizabeth Boyle, Arthur L. Burnett -- Chapter 59. Osteoporosis in Men and Women / Kendall F. Moseley, Suzanne M. Jan de Beur -- Chapter 60. Testosterone Replacement Therapy in Men and Women / Diala El-Maouche, Adrian Dobs.
  • 2007
    edited by Richard E. Ashcroft ... [et al.].
    Status: Not Checked OutLane Catalog Record
  • 2016 Springer
    Tim Benson, Grahame Grieve.
    PART 1 Principles of Health Interoperability -- Chapter 1 The Health Information Revolution -- Chapter 2 Why Interoperability is Hard -- Chapter 3 Models -- Chapter 4 UML, XML and JSON -- Chapter 5 Information Governance -- Chapter 6 Standards Development Organizations -- PART 2 Terminologies and SNOMED CT -- Chapter 7 Clinical Terminology -- Chapter 8 Coding and Classification Schemes -- Chapter 9 SNOMED CT -- Chapter 10 SNOMED CT Concept Model -- Chapter 11 Implementing SNOMED CT -- PART 3 HL7 and Interchange Formats -- Chapter 12 HL7 Version 2 -- Chapter 13 The HL7 V3 RIM -- Chapter 14 Constrained Information Models -- Chapter 15 CDA -- Clinical Document Architecture -- Chapter 16 HL7 Dynamic Model -- Chapter 17 Sharing Documents and IHE XDS -- PART 4 FHIR -- Chapter 18 Principles of FHIR -- Chapter 19 The FHIR RESTful API -- Chapter 20 FHIR Resources -- Chapter 21 Conformance and Terminology -- Chapter 22 Implementing FHIR.
  • 2012 Springer
    Tim Benson.
    Part 1. Principles of Health Interoperability -- The Health Information Revolution -- Why Interoperability is Hard -- Models -- UML and XML -- Privacy -- Standards Development Organizations -- Part 2. HL7 and Interchange Formats -- HL7 Version 2 -- The HL7 V3 RIM -- Constrained Information Models -- Clinical Document Architecture -- HL7 Dynamic Model -- IHE XDS -- Part 3. SNOMED and Terminology -- Clinical Terminology -- Coding and Classification Schemes -- SNOMED CT -- SNOMED CT Concept Model -- Using SNOMED and HL7 Together.
  • 2010 Springer
    Tim Benson.
    The health information revolution -- Why interoperability is hard -- Models -- UML and XML -- Standards development organizations -- HL7 version 2 -- The HL7 V3 RIM -- Constrained information models -- Clinical document architecture -- HL7 dynamic model and IHE XDS -- Clinical terminology -- SNOMED CT -- Using SNOMED and HL7 together.
  • 2005 Springer
    edited by Frans P. Nijkamp and Michael J. Parnham.
  • 2011 Springer
    edited by Frans P. Nijkamp and Michael J. Parnham.
  • 2012 ClinicalKey
    Gerhard Meisenberg, William H. Simmons.
    Drs. Gerhard Meisenberg and William H. Simmons covers the latest developments in the field, including genome research, the molecular basis of genetic diseases, techniques of DNA sequencing and molecular diagnosis, and more. An updated and expanded collection of figures and access to the fully searchable text, USMLE test questions, clinical case studies and more makes this the resource for understanding all aspects of biochemistry needed in medicine. Tap into the most up-to-date coverage of new developments in genome research, the molecular basis of genetic diseases, techniques of DNA sequencing and molecular diagnosis, RNA interference as a mechanism both for regulation of gene expression and for anti-viral defense, and more. Gain a clear visual understanding through new and updated figures that provide current and relevant guidance. Make the link between basic science and clinical medicine with new Clinical Example boxes in nearly every chapter. Focus on the most essential biochemistry principles and how they apply to clinical medicine.
  • v. 2-15, 1995-2004. ScienceDirect
  • 2007
    edited by Harold Kalant, Denis M. Grant, Jane Mitchell.
    Status: Not Checked OutLane Catalog Record
  • 2002 CRCnetBASE
    Alvan R. Feinstein.
    Also available: Print – 2002
  • 2013 Cambridge
    edited by David Mabey, Geoffrey Gill, Sir Eldryd Parry, Martin W. Weber, Christopher J.M. Whitty.
    "Principles of Medicine in Africa combines classical clinical medicine with a rich understanding of the major environmental and cultural influences on health and disease, providing comprehensive guidance for anyone intending to practise medicine in Africa. Disease is presented in the context of family and culture, and the effects of inequality and problems of limited resources are addressed."--Excerpt from publisher notes.
  • 2012 Springer
    W. Konrad Karcz, Oliver Thomusch, (eds.).
    For physicians and surgeons entrusted with the care of patients with morbid obesity and related diseases; also for nurses and other professionals on the team. âPrinciples of Metabolic Surgeryâ delivers a succinct account of current knowledge and an excellent overview of modern treatment strategies for morbid obesity. Attractively designed, this user-friendly textbook provides the latest on therapy, monitoring, and management, including: -Completely up-to-date coverage of modern metabolic surgery -Current understanding of the pathophysiology of morbid obesity -Current clinical therapy strategies for conservative and surgical approaches -Recent references In concise, readable chapters, this well-illustrated textbook outlines major concerns and considerations surrounding metabolic surgery. With respect to new insights from basic and clinical research, clear guidelines and practical clinical advice are given to improve the outcome of treatment for morbid obesity.
  • 2013 Springer
    Kyriakos Anastasiadis, Polychronis Antonitsis, Helena Argiriadou.
    Minimal extracorporeal circulation (MECC) systems have been designed in order to reduce dramatically the side-effects of conventional extracorporeal circulation while serving as a safe perfusion technique for open heart surgery with cardiopulmonary bypass. However, the low penetration of this technology in contemporary practice means that few surgical centres have accumulated sufficient experience to share it with the scientific community. Furthermore, much of the knowledge on the use of MECC systems in cardiac surgery is widely dispersed in the literature. This book aims to provide an up-to-date and comprehensive overview of MECC, offering practical advice on how to use MECC systems for those new to the field as well as tips, pitfalls, results, and latest developments. It also offers a systematic review of all published studies on a variety of MECC systems. The book will enable physicians to gain a better understanding of these new systems as well as to understand the rationale for their use in cardiac surgery. MECC requires a multidisciplinary approach, and this book will serve as an essential reference for all health care professionals working in the cardiac surgical operating room, in particular cardiothoracic surgeons, anaesthesiologists, and perfusionists.
  • 2005 Springer
    edited by Marschall S. Runge, Cam Patterson ; foreword by James T. Willerson.
    Cardiovascular genetics / Christopher Semsarian and Christine Seidman -- Molecular biology applications in cardiovascular medicine / Eugene Yang ... [et al.] -- Genomics and its application to cardiovascular disease / Robert Roberts -- Gene therapy and cardiovascular diseases / Yi Chu, Neal L. Weintraub, and Donald D. Heistad -- Stem cells and progenitor cells in cardiovascular disease / Jalees Rehman and Keith L. March -- Development of the vertebrate heart / Mabelle Ashe and David Bader -- Inherited myocardial diseases / Elizabeth M. McNally -- Receptor-signaling pathways in heart failure / Shayela Suvarna ... [et al.] -- Recent insights into the molecular pathophysiology of viral myocarditis / Tony Tran, Roger D. Rossen, and Douglas L. Mann -- Genetic underpinnings of cardiogenesis and congenital heart disease / Vidu Garg and Deepak Srivastava -- Coronary artery development / Mark W. Majesky -- Atherosclerosis / George A. Stouffer -- Antiplatelet drugs / Karlheinz Peter -- Myocardial infarction / D. Douglas Miller and Steven C. Herrmann -- Transplant arteriopathy: pathology, pathogenesis, and prospects for treatment / Joannis Vamvakopoulos ... [et al.] -- Thrombolysis: scientific basis for current theory / Guy L. Reed III -- Coronary restenosis / Julius Aitsebaomo ... [et al.] -- Induction and patterning of purkinje fiber network / Takashi Mikawa ... [et al.] -- Mechanisms of sudden cardiac death / Wayne E. Cascio -- Gene therapy for cardiac arrhythmias / J. Kevin Donahue and Eduardo Marbçn -- Genetics and arrhythmias / Kui Hong and Ramon Brugada -- Therapeutic angiogenesis for ischemic vascular disease / Jai Pal Singh and J. Anthony Ware -- Nitric oxide in cardiovascular biology and pathophysiology / Marshall A. Corson -- Vasculitis / Ronald J. Falk and J. Charles Jennette -- Primary pulmonary hypertension / Evangelos D. Michelakis and Stephen L. Archer -- The molecular basis of cerebrovascular malformations / Douglas A. Marchuk -- Thrombotic vascular disease / Stephan Moll and Gilbert C. White II -- Risk factors / Ngoc-Anh Le and W. Virgil Brown -- Vascular aging: from molecular to clinical cardiology / Samer S. Najjar and Edward G. Lakatta -- Oxidative stress / Nageswara R. Madamanchi and Marschall S. Runge -- Diabetes mellitus: an important cardiovascular risk factor / David R. Clemmons -- Vascular inflammation as a cardiovascular risk factor / Allan R. Brasier and Adrian Recinos III, and Mohsen S. Eledrisi.
  • 2013 Ovid
    editors, Dongfeng Tan, Henry T. Lynch.
    Section I. Introduction of cancer biology and cancer genetics -- Section II. Molecular techniques -- Section III. Molecular tests and cancer management -- Section IV. Molecular diagnostics of common malignancies -- Section V. Molecular basis of cancer therapeutics -- Section VI. Personalized medicine and targeted therapy of cancer -- Section VII. Future of molecular diagnostics and personalized cancer medicine.
  • 2006 Springer
    edited by Marschall S. Runge, Cam Patterson ; foreword by Victor A. McKusick.
    Also available: Print – 2006
  • 2005 Karger
    volume editors, Andrew Freese ... [et al.].
    The molecular basis of intervertebral disc degeneration / Leo, B.M.; Walker, M.H.; Anderson, D.G. -- Genetics of degenerative disc disease / Kurpad, S.N.; Lifshutz, J. -- Gene therapy for degenerative disc disease / Kim, J.; Gilbertson, L.G.; Kang, J.D. -- Bone morphogenetic proteins: spinal fusion applications / Bomback, D.A.; Grauer, J.N. -- Cellular and gene therapy approaches to spinal cord injury / Steinmetz, M.P.; Liu, J.K.; Boulis, N.M. -- Neural stem cell transplantation for spinal cord repair / Iwanami, A. ... [et al.] -- Contemporary applications of functional and stereotactic techniques for molecular neurosurgery / Couldwell, W. -- Xeno-neurotransplantation / Schumacher, J.M. -- Molecular mechanisms of epilepsy and gene therapy / Telfeian, A.; Celix, J.; Dichter, M. -- Adeno-associated viral (AAV) vectors for clinical gene therapy in the brain / Samulski, R.J. -- Molecular mechanisms of epilepsy and gene therapy / Telfeian, A.; Celix, J.; Dichter, M. -- Emerging treatment of neurometabolic disorders / Brady, R.O.; Brady, R.O. Jr. -- Gene therapy for Parkinson's disease / Hadaczek, P.; Daadi, M.; Bankiewicz, K. -- Simplifying complex neurodegenerative diseases by gene chip analysis / Scherzer, C.R.; Gullans S.R.; Jensen, R.V. -- Molecular pathology of dementia: emerging treatment strategies / Gouras, G.K. -- Expanding the role of deep brain stimulation from movement disorders to other neurological disorders / Leone, M. ... [et al.] -- Molecular mediators of pain / Chaudhary P.; Burchiel, K. -- Gene transfer in the treatment of pain / Fink, D.; Mata, M.; Glorioso, J.C. -- Gene discovery underlying stroke / Barone, F.C.; Read, S.J. -- Molecular mediators of hemorrhagic stroke / Macdonald, R.L. -- Advances towards cerebrovascular gene therapy / Watanabe, Y.; Heistad, D.D. -- Ex vivo gene therapy and cell therapy for stroke / Kondziolka, D.; Sheehan, J.; Niranjan, A. -- Neurosurgical applications for polymeric drug delivery systems / Wang, P.P.; Brem, H. -- Immunotherapy strategies for treatment of malignant gliomas / Harshyne, L.; Flomenberg, P.; Andrews, D.W. -- 'Glioma-genesis': signaling pathways for the development of molecular onco-therapy / Kapoor, G.S.; O'Rourke, D.M. -- Oncolytic viral therapy for glioma / Lamfers, M.L.M.; Visted, T.; Chiocca, E.A. -- Molecular neurosurgery in the pituitary gland: gene transfer as adjunctive treatment strategy -- Castro, M.G. ... [et al.] -- Stem cells for targeting CNS malignancy / Yip, S.; Sidman, R.L.; Snyder, E.Y.
  • 2008 Springer
    edited by Miguel H. Bronchud, MaryAnn Foote, Giuseppe Giaccone, Olufunmilayo Olopade, Paul Workman ; foreword by Karen Antman.
    Selecting the right targets for cancer therapy / Miguel H. Bronchud -- Clinical importance of prognostic factors: moving from scientifically interesting to clinically useful / N. Lynn Henry and Daniel F. Hayes -- Genetic markers in sporadic tumors / Elena Tamborini ... [et al.] -- Genetic markers in breast tumors with hereditary predisposition / Tatyana A. Grushko and Olufunmilayo I. Olopade -- Circulating tumor markers / Alan Horwich and Gill Ross -- Antibody-based proteomics analysis of tumor cell signaling pathways / Steven Pelech and Hong Zhang -- Gene expression arrays for pathway analysis in cancer research / Xiang Sean Yu ... [et al.] -- Signaling pathways in cancer / Daniel Kalderon -- Estrogen receptor pathways and breast cancer / Jing Peng and V. Craig Jordan -- Cyclin-dependent kinases and their regulators as potential targets for anticancer therapeutics / Marcos Malumbres -- Angiogenesis switch pathways / Jaume Piulats and Francesc Mitjans -- Apoptosis pathways and new anticancer agents / Frank A.E. Kruyt, Jose A. Rodriguez, and Giuseppe Giaccone -- Genomic instability, DNA repair pathways and cancer / Gabriel Capellá, Josep Balart, and Miquel Angel Peinado -- Epigenomics and cancer / Isabel Lopéz de Silanes and Manel Esteller -- Harnessing the power of immunity to battle cancer: Much ado about nothing or All's well that ends well? / Angelo A. Cardoso -- Aurora Kinases: a new target for anticancer drug development / Teresa Macarulla, Francisco Javier Ramos, and Josep Tabernero -- Emerging molecular therapies: drugs interfering with signal transduction pathways / Alison H.M. Reid, Richard Baird, and Paul Workman -- Suicide gene therapy / Silke Schepelmann, Ion Niculescu-Duvaz, and Caroline J. Springer -- Genotypes that predict toxicity and genotypes that predict efficacy of anticancer drugs / Rosario García-Campelo ... [et al.] -- A personal account of the chemoprevention of breast cancer: possible or not possible? / V. Craig Jordan.
  • 2011 Springer
    Shan R. Baker.
  • 2013 CRCnetBASE
    edited by Rodrigo Quian Quiroga, Stefano Panzeri.
    Understanding how populations of neurons encode information is the challenge faced by researchers in the field of neural coding. Focusing on the many mysteries and marvels of the mind has prompted a prominent team of experts in the field to put their heads together and "fire up" a book on the subject. Simply titled Principles of Neural Coding, this book covers the complexities of this discipline. It centers on some of the major developments in this area and presents a complete assessment of how neurons in the brain encode information. The book's collaborators contribute various chapters that describe results in different systems (visual, auditory, somatosensory perception, etc.) and different species (monkeys, rats, humans, etc.). The introductory chapters concentrate on the recording and analysis of the firing of single and multiple neurons as well as the analysis and recording of other integrative measures of network activity and network states, such as local field potentials or current source densities. The book then moves forward with a description of the principles of neural coding for different functions and in different species and concludes with theoretical and modeling works describing how information processing functions are implemented. The text not only contains the most important experimental findings, but gives an overview of the main methodological aspects for studying neural coding. In addition, the book describes alternative approaches based on simulations with neural networks and in silico modeling in this highly interdisciplinary topic. It can serve as an important reference to students and professionals.
  • 2013
    edited by Eric R. Kandel, James H. Schwartz, Thomas M. Jessell, Steven A. Siegelbaum, A.J. Hudspeth; art editor, Sarah Mack.
    Status: Not Checked OutLane Catalog Record
    "The fifth edition has been completely updated to reflect the tremendous amount of new research and development in neuroscience in the last decade. Lead author Eric Kandel was awarded the Nobel Prize in Physiology or Medicine in 2000"--Provided by publisher.
  • 2016
    Liqun Luo.
    Status: Not Checked OutLane Catalog Record
    1. An invitation to neurobiology. Nature and nurture in brain function and behavior ; How the nervous system organized ; General methodology ; Summary -- 2. Signaling within neurons. Cell biological and electrical properties of neurons ; How do electrical signals propagate from the neuronal cell body to its axon terminals? ; Summary -- 3. Signaling across synapses. How is neurotransmitter release controlled at the presynaptic terminal? ; How do neurotransmitters act on postsynaptic neurons? ; Summary -- 4. Vision. How do rods and cones detect light signals? ; How are signals from rods and cones analyzed in the retina? ; How is information processed in the visual cortex? ; Summary -- 5. Wiring of the visual system. How do retinal ganglion cell axons find their targets? ; How do experience and neuronal activity contribute to wiring? ; How do molecular determinants and neuronal activity work together? ; Visual system development in drosophila : linking cell fate to wiring specificity ; Summary -- 6. Olfaction, taste, audition, and somatosensation. How do we sense odors? ; How do worms and flies sense odors? ; Taste : to eat, or not to eat? ; Audition : how do we hear and localize sounds? ; Somatosensation : how do we sense body movement, touch, temperature, and pain? ; Summary -- 7. Wiring of the nervous system. How does wiring specificity arise in the developing nervous system? ; Assembly of olfactory circuits : how do neural maps form? ; How do ~20,000 genes specify 10¹⁴ connections? ; Summary -- 8. Motor and regulatory systems. How is movement controlled? ; How does the brain regulate the functions of internal organs? ; How is eating regulated? ; How are circadian rhythms and sleep regulated? ; Summary -- 9. Sexual behavior. How do genes specify sexual behavior in the fly? ; How are mammalian sexual behaviors regulated? ; Summary -- 10. Memory, learning, and synaptic plasticity. Prelude: What is memory, and how is it acquired by learning? ; How is synaptic plasticity achieved? ; What is the relationship between learning and synaptic plasticity? ; Where does learning occur, and where is memory stored in the brain? ; Summary -- 11. Brain disorders. Alzheimer's disease and other neurodegenerative diseases ; Psychiatric disorders ; Neurodevelopmental disorders ; Summary -- 12. Evolution of the nervous system. General concepts and approaches in evolutionary analysis ; Evolution of neuronal communication ; Evolution of sensory systems ; Evolution of nervous system structure and development ; Summary -- 13. Ways of exploring. Animal models in neurobiology research ; Genetic and molecular techniques ; Anatomical techniques ; Recording and manipulating neuronal activity ; Behavioral analyses ; Summary and perspectives -- Glossary.
  • 2012 ScienceDirect
    2012 ClinicalKey
    [edited by] Richard G. Ellenbogen, Saleem I. Abdulrauf, Laligam N. Sekhar.
    Part 1.General Overview . Landmarks in the History of Neurosurgery / James Tait Goodrich ; Clinical Evaluation of the Nervous System / Gerald A. Grant, Richard G. Ellenbogen ; Principles of Modern Neuroimaging / Kathleen R. Tozer Fink, Michael R. Levitt, James R. Fink ; Principles of Surgical Positioning / Genèvieve Lapointe, Joanna Kemp, Govind Rajan, Grace Elisabeth Walter, Saleem I. Abdulrauf. -- Part 2.Pediatric Neurosurgery. Spinal Dysraphism and Tethered Spinal Cord / Leslie N. Sutton, Joel A. Bauman, Luke J. Macyszyn ; Hydrocephalus in Children and Adults / Alia Hdeib, Alan R. Cohen ; Developmental Anomalies: Arachnoid Cysts, Dermoids, and Epidermoids / David F. Jimenez, Jennifer Gentry Savage, Mical Samuelson ; Diagnosis and Surgical Options for Craniosynostosis / Mitchel Seruya, Suresh N. Magge, Robert F. Keating ; The Chiari Malformations and Syringohydromyelia / R. Shane Tubbs, Todd C. Hankinson, John C. Wellons, III ; Posterior Fossa and Brainstem Tumors in Children / Adrienne Weeks, Aria Fallah, James T. Rutka ; Causes of Nontraumatic Hemorrhagic Stroke in Children: Pediatric Moyamoya Syndrome / Edward R. Smith, R. Michael Scott. -- Part 3.Vascular Neurosurgery. Cerebrovascular Occlusive Disease and Carotid Surgery / Geoffrey Appelboom, Matthew Piazza, E. Sander Connolly, Jr. ; Intracranial Aneurysms / Christopher S. Eddleman, Christopher C. Getch, Bernard R. Bendok, H. Hunt Batjer ; Vascular Malformations (Arteriovenous Malformations and Dural Arteriovenous Fistulas) / Ghaus M. Malik, Sandeep S. Bhangoo ; Cavernous Malformations Management Strategies / Aimee Two, Ali K. Ozturk, Murat Gunel ; Spontaneous Intracerebral Hemorrhage / Alan Hoffer, Justin Singer, Nicholas C. Bambakidis, Warren Selman ; Endovascular Neurosurgery / Sabareesh K. Natarajan, Adnan H. Siddiqui, L. Nelson Hopkins, Elad I. Levy ; Cerebral Revascularization for Giant Aneurysms of the Transitional Segment of the Internal Carotid Artery / Jonathon J. Lebovitz, Jorge L. Eller, Justin M. Sweeney, Deanna Sasaki-Adams, Aneela Darbar, Sheri K. Palejwala, Anja-Maria Radon, Saleem I. Abdulrauf. -- Part 4.Trauma. Intracranial Hypertension / Ryan Morton, Richard G. Ellenbogen ; Closed Head Injury / Clifford M. Houseman, Shawn A. Belverud, Raj K. Narayan ; Penetrating Brain Injury / Michael Cirivello, Randy S. Bell, Rocco A. Armonda ; Traumatic Skull and Facial Fractures / Fred H. Geisler, Eduardo Rodriguez, Paul N. Manson. -- Part 5.Spine. Injuries to the Cervical Spine / M. Yashar S. Kalani, Aristotelis S. Filippidis, Nicholas Theodore ; Thoracolumbar Spine Fractures / Edward M. Marchan, George M. Ghobrial, James S. Harrop ; Intradural Extramedullary and Intramedullary Spinal Cord Tumors. / Michaël Bruneau, Florence Lefranc, Danielle Balériaux, Jacques Brotchi ;Treatment of Spinal Metastatic Tumors / Ilya Laufer, Marcella A. Madera, Daniel Sciubba, Ziya L. Gokaslan ; Spinal Cord Injury / David W. Cadotte, Michael G. Fehlings ; Syringomyelia / Spyros Sgouros ; Craniovertebral Junction: A Reappraisal / Atul Goel ; Degenerative Spine Disease / James K.C. Liu, Edward C. Benzel ; Pediatric and Adult Scoliosis / David W. Polly, Jr., A. Noelle Larson (Part I) Frank Schwab, Benjamin Blondel, Virginie Lafage (Part II) ; Acute Nerve Injuries / Lynda J-S Yang ; Entrapment Neuropathies / Mikhail Gelfenbeyn, Henry Marsh. -- Part 6.Tumors. Low-Grade and High-Grade Gliomas / Nader Sanai, Mitchel S. Berger ; Metastatic Brain Tumors / Juanita M. Celix, Daniel L. Silbergeld ; Meningiomas / Federico Landriel, Peter Black ; Tumors of the Pineal Region / Christian Matula ; Cerebellopontine Angle Tumors / Madjid Samii, Venelin M. Gerganov ; Craniopharyngiomas and Suprasellar Tumors / Juraj ten¿o ; Pituitary Tumors: Diagnosis and Management / Carrie R. Muh, Nelson M. Oyesiku ; Endoscopic Approaches to Ventricular Tumors and Colloid Cysts / Scott D. Wait, Charles Teo ; Microsurgical Approaches to the Ventricular System / Timothy H. Lucas, II, Richard G. Ellenbogen ; Skull Base Approaches / Salvatore Di Maio, Laligam N. Sekhar ; Endoscopic Approaches to Skull Base Lesions, Ventricular Tumors, and Cysts / Nancy McLaughlin, Daniel M. Prevedello, Daniel Kelly, Ricardo L. Carrau, Amin B Kassam, Scott D. Wait, Charles Teo, Aneela Darbar, Sheri K. Palejwala. -- Part 7.Radiosurgery. Application of Current Radiation Delivery Systems and Radiobiology / Jay Loeffler, Helen Shih, Melin Khandekar ; Radiosurgery of Central Nervous System Tumors / Douglas Kondziolka, Ajay Niranjan, L. Dade Lunsford, John C. Flickinger ; Stereotactic Radiosurgery of Vascular Malformation / Chun Po Yen, Chris Cifarelli, David Schlesinger, Jason P. Sheehan. -- Part 8.Functional/Pain. Trigeminal Neuralgia / Gerald A. Grant, John D. Loeser ; Surgical Therapy for Pain / Giovanni Broggi, Francesco Acerbi, Morgan Broggi, Giuseppe Messina / Spasticity: Classification, Diagnosis, and Management / Michael R. Levitt, Samuel R. Browd ; Surgery for Temporal Lobe Epilepsy / Jeffrey G. Ojemann, Carlo Giussani, Carlo Marras ; Extratemporal Procedures and Hemispherectomy for Epilepsy / Gwyneth Hughes, William Bingaman ; Basic Principles of Deep Brain Stimulation for Movement Disorders, Neuropsychiatric Disorders, and New Frontiers / Alexander S. Taghva, Chima O. Oluigbo, Ali R. Rezai. -- Online only: E44 Minimal Access Skull Base Approaches / Paolo Cappabianca, Isabella Esposito, Luigi Maria Cavallo, Felice Esposito, Vita Stagno.
  • 2014 Springer
    Alan David Kaye, Scott Francis Davis, editors.
    1. Introduction to the Operating Room -- 2. Anatomy of Intraoperative Monitoring -- 3. Cellular Neurophysiology -- 4. Electrophysiology and Bioinstrumentation -- 5. Anesthesiology and Intraoperative Electrophysiological Monitoring -- 6. Somatosensory Evoked Potential Monitoring -- 7. Motor Evoked Potentials -- 8. Electromyography (EMG) -- 9. Brainstem Auditory Evoked Potentials -- 10. Electroencephalography -- 11. The H-Reflex and F-Response -- 12. Monitoring Procedures of the Spine -- 13. Intraoperative Monitoring for Surgery of the Spinal Cord and Cauda Equina -- 14. Monitoring Posterior Fossa Craniotomies -- 15. Intraoperative Monitoring for Carotid Endarterectomy -- 16. Monitoring for ENT Procedures -- 17. Peripheral Nerve Monitoring -- 18. Intraoperative Cortical Mapping: Basic Concepts, Indications, and Anesthesia Considerations -- 19. Neurological Assessment and Correlation in Spinal Cord Nerve Root Pathology -- 20. Electrophysiological Assessment of Spinal Cord Pathology in Pain Medicine -- 21. Spinal Cord Stimulation: Principles and Applications -- 22. New Vistas: Small-Pain-Fibers Method of Testing for Spinal Cord Assessment in Pain States.
  • 2008 Springer
    edited by Antolin M. Llorente.
    Introduction and theoretical foundations / Sara A. Lawless, Julie K. Ries, and Antolin M. Llorente -- American population estimates, trends in American immigration, and neuropsychology : influences on assessment and inferential processes with Hispanic populations / Antolin M. Llorente -- Hispanic populations : special issues in neuropsychology / Antolin M. Llorente -- Intellectual abilities : theoretical and applied assessment considerations / Christian von Thomsen, Lori Gallup, and Antolin M. Llorente -- Language : development, bilingualism, and abnormal states / Christine French and Antolin M. Llorente -- The neuropsychological assessment of the Hispanic client / Antolin M. Llorente and Deborah Weber -- Hispanics and cultural bias : test development and applications / Peter Smith, Eric Lane, and Antolin M. Llorente -- Rehabilitation / Julie K. Ries, Brian Potter, and Antolin M. Llorente.
  • 2013 Springer
    Mark V. Sauer, editor.
    The versatility of oocyte and embryo donation has proven to be extremely valuable to both patients and doctors engaged in reproductive medicine. Originally thought to be applicable only to a rather small subset of infertile women, today busy practices commonly recommend the procedure and it is estimated that nearly all of the 400 or more IVF programs in the United States provide these services. Oocyte and embryo donation has established itself as a mainstay procedure within assisted reproductive care, and the breadth, depth and complexity of practice is deserving of focused attention. Much has changed within the field of oocyte and embryo donation since the publication of the first edition of Principles of Oocyte and Embryo Donation in 1998, thus the need for a completely updated and more expansive text. The second edition of this book provides an overview of the major issues affecting men and women engaged in the practice of oocyte and embryo donation. A primary emphasis has been placed on defining the standards of practice that have evolved over the past 30 years, clearly stating the outcomes expected from adhering to these established protocols. Details of both the basic science and the clinical medicine are presented together and attention is also focused on the non-reproductive aspects inherent to this unique method of assisted reproduction that involves opinions from lawyers, ethicists, mental health care professionals and theologians. Oocyte and embryo donation requires a working knowledge of the medicine, the law and the ethics that underlies its foundation. This book is intended to serve as a complete and comprehensive reference for all health care professionals that provide services related to egg donation, reproductive endocrinologists, obstetrician- gynecologists, and fellows and residents entering the fertility field.
  • 2012 Springer
    Peter Pietschmann (ed.).
  • F. Scott Kieff.
    Status: Not Checked OutLane Catalog Record
  • 2012
    editors, Mamatha M Lala, Rashid H Merchant ; forewords, Hoosen Coovadia, Ishwar S Gilada, Janak K Maniar.
    Status: Not Checked OutLane Catalog Record
  • Google Books
    translated from the 5th German ed. (1902) by Edwrd Bradford Titchener.
    Also available: Print – v. 1, 1904.
  • 2007
    Daniel L. Hartl, Andrew G. Clark.
    Status: Not Checked OutLane Catalog Record
    This edition provides a balanced presentation of theory and observation. It introduces the principles of genetics and statistics that are relevant to population studies, and examines the forces affecting genetic variation from the molecular to the organismic level.
  • 2012 Thieme eNeurosurgery
    [edited by] Anil Nanda.
    General considerations -- Surgery of the posterior cranial fossa: historical aspects -- Microsurgical anatomy of the posterior cranial fossa -- Neuroimaging of the posterior fossa -- Neurosurgical pathology of the posterior fossa -- Neurologic entities of the posterior fossa -- Disease-based management -- Congenital Chiari malformations -- Trauma to the temporal bone -- Posterior fossa infections -- Temporal bone surgery -- Hemangiomas and dural fistulas -- Surgical techniques -- Basic concepts in posterior fossa surgery -- Surgical management of petroclival tumors -- Jugular bulb tumors -- Retromastoid approach: techniques and results -- Acoustic neuromas: translabyrinthine approaches -- Middle fossa craniotomy -- Microvascular decompressions for hemifacial spasm and trigeminal neuralagia -- Management of posterior cranial fossa pathology: gamma knife radiosurgery -- Aneurysms of the basilar trunk: far lateral and petrosal approaches -- Approaches and management of basilar tip aneurysms -- Endovascular treatment of posterior circulation aneurysms -- Posterior interhemispheric approach to pineal region and brainstem -- Posterior fossa arteriovenous malformations and cavernous angiomas -- Shunt surgery for posterior fossa lesions -- Surgical management of pediatric posterior fossa tumors.
  • 2007 Springer
    Jan Drenth ; with major contribution from Jeroen Mesters.
  • 2012 Cambridge
    edited by John I. Nurnberger Jr., Wade H. Berrettini.
    Contribution of genetic epidemiology to our understanding of psychiatric disorders / Kathleen Ries Merikangas, Anibal Cravchik -- A basic overview of contemporary human genetic analysis strategies / Ondrej Libiger, Nicholas J. Schork -- DNA methods / David W. Craig -- In silico analysis strategies and resources for psychiatric genetics research / Ali Torkamani, Trygve Bakken, Nicholas J. Schork -- Gene expression studies in psychiatric disorders / Alexander B. Niculescu, III -- Pharmacogenetics in psychiatry / Falk W. Lohoff -- Functional validation of candidate genetic susceptibility factors for major mental illnesses / Akira Sawa [and others] -- Epigenetic mechanisms in drug addiction and depression / William Renthal, Eric J. Nestler -- Panic disorder / Ardesheer Talati, Myrna M. Weissman -- The genetics of phobic disorders and generalized anxiety disorder / Raymond R. Crowe -- Genetic contributions to obsessive-compulsive disorder (OCD) and OCD-related disorders / Dennis L. Murphy [and others] -- Post-traumatic stress disorder / Michael J. Lyons, Tyler Zink, Karestan C. Koenen -- Antisocial behavior : gene-environment interplay / Laura A. Baker [and others] -- Learning disabilities / Shelley D. Smith -- Attention-deficit hyperactivity disorder / Josephine Elia [and others] -- Autism and autism spectrum disorders / Daniel H. Geschwind, Maricela Alarcon -- The genetics of bipolar disorder / John R. Kelsoe -- The genetics of major depression / James B. Potash -- The genetics of schizophrenia / Hugh M.D. Gurling, Andrew McQuillin -- The genetics of anorexia and bulimia nervosa / Andrew W. Bergen, Jennifer Wessel, Walter H. Kaye -- Genetics and common human obesity / R. Arlen Price -- Alcoholism / Howard J. Edenberg -- Nicotine dependence / Sarah M. Hartz, Laura J. Bierut -- Human molecular genetics of opioid addiction / Mary Jeanne Kreek [and others] -- Genetics of stimulant dependence / Joseph F. Cubells, Yi-Lang Tang -- Genetics of personality disorders / C. Robert Cloninger -- Ethical issues in behavioral genetics / Stephen H. Dinwiddie, Jinger Hoop, Elliot Gershon -- Genetics of Tourette syndrome and related disorders / Maria G. Motlagh, Thomas V. Fernandez, James F. Leckman -- Endophenotypes in psychiatric genetics / Andrew C. Chen, Madhavi Rangaswamy, Bernice Porjesz -- Developmental disorders / Craig A. Erickson, Khendra I. Peay, Christopher J. McDougle -- Alzheimer's disease / Carlos Cruchaga, John S.K. Kauwe, Alison M. Goate.
  • 2009
    edited by F. Douglas Scutchfield, C. William Keck.
    Status: Not Checked OutLane Catalog Record
    Concepts and definitions of public health practice / F. Douglas Scutchfield and C. William Keck -- History and development of public health / Elizabeth Fee -- Emergence of a new public health / C. William Keck and F. Douglas Scutchfield -- Social determinants of health : their influence on personal choice, environmental exposures, and health care / Steven H. Woolf and Robert L. Phillips, Jr. -- Public health policy and the policy-making process / Thomas C. Ricketts -- The legal basis for public health practice / Edward P. Richard III and Kahterine C. Rathbun -- Public health ethics / James C. Thomas -- The federal contribution to public health / William L. Roper -- The state public health agencies / A. Richard Melton and Laverne Alves Snow -- The local health department / Carolyn J. Leep, Grace Gorenflo, and Patrick M. Libbey -- Epidemiology and public health data / Donna F. Stroup and Stephen B. Thacker -- Community health planning and programming / Laura H. Downey and F. Douglas Scutchfield -- Prevention effectiveness / Kakoli Roy, Zhuo Chen, and Anne Haddix -- Behavioral community health needs assessment / John Elder, Paula M. Usita, and Noé Crespo -- The management of public health organizations / Julia F. Costich and J. Michael Moser -- Performance measurement and management in public health / Paul K. Halverson -- Public health workforce / Patricia M. Sweeney, Kristine M. Gebbie, and Hugh Tilson -- Leadership in public health practice / Cynthia D. Lamberth and Louis Rowitz -- Chronic disease control / Janet Collins, Linnea Evans and David V. McQueen -- Reducing tobacco use / Michael P. Eriksen and Lawrence W. Green -- Drug and alcohol issues in public health / C.G. Leukefeld ... [et al.] -- Infectious disease control / Alan R. Hinman -- Public health preparedness / Linda Young Landesman, Isaac B. Weisfuse, and Susan Waltman -- Environmental health in public health / Alan M. Jacobs and DuWayne Porter -- Primary care and public health / Michael R. King, Kevin A. Pearce, and Samuel C. Matheny -- Maternal and child health / Carol Hogue -- Injury control / María Seguí-Gómez and Susan P. Baker -- Oral diseases : the neglected epidemic / Myron Allukian Jr. -- The public health laboratory / Ronald L. Cada and Ralph Timperi -- Global health / Alfredo E. Vergara and Sten H. Vermund -- The future of public health / C. William Keck and F. Douglas Scutchfield.
  • 2014 ClinicalKey
    Steven E. Weinberger, Barbara A. Cockrill, Jess Mandel.
    Principles of Pulmonary Medicine helps you master the foundations of pulmonary medicine without being overwhelmed! This concise, easy-to-read medical reference book correlates basic science principles with the radiologic, pathologic, and clinical aspects of respiratory disease to provide an integrated, accessible approach to the study of pulmonary medicine. Focus on the clinical aspects and treatment of specific pulmonary and respiratory diseases, and understand the anatomy, physiology, and pathophysiology relevant to major pulmonary disorders.Apply the material to real-life practice with case-based pulmonology questions covering topics including pulmonary function tests, physiologic data, and results of arterial blood gas testing.
  • 2008
    Steven E. Weinberger, Barbara A. Cockrill, Jess Mandel.
  • 2010 Springer
    Edmo Atique Gabriel, Tomas A. Salerno (Editors).
    Anatomy of the lungs -- Respiratory physiology -- Histological features of lungs -- Cellular and molecular aspects of lung function, its control and regulation -- Imaging evaluation of the thorax -- Endothelial protection during heart surgery and lung transplantation -- Vascular endothelial growth factor and pulmonary injury -- Aprotinin decreases lung reperfusion injury and dysfunction -- Effects of prostaglandin E1 and nitroglycerin on lung preservation -- Endothelin and ischemia-reperfusion injury -- L-arginine and ischemia-reperfusion injury -- The role of nitric oxide in pulmonary ischemia-reperfusion injury -- Activity of glutathione-related enzymes in ischemia and reperfusion injury -- Heart histopathology in ischemia-reperfusion injury -- Beating heart surgery and pulmonary ischemia and reperfusion injury -- Mechanisms of pulmonary edema -- Idiopathic pulmonary hypertension: new challenges -- Chronic thromboembolic pulmonary hypertension and pulmonary endarterectomy -- Eisenmenger syndrome -- Disseminated intravascular coagulation in cardiac surgery -- Pulmonary arterial hypertension -- The extracorporeal circulation circuit versus bioengineering biomaterials -- Ischemic preconditioning and lung preservation -- Impact of cardiopulmonary bypass on pulmonary hemodynamic variables -- Impact of cardiopulmonary bypass on gas exchange features -- Pulmonary energy metabolism and multiple inflammatory repercussions -- Benefits of ultrafiltration for pulmonary function -- Principles of pulmonary protections during heart surgery: benefits of hemofiltration for pulmonary function -- Determining hemodynamic parameters -- Extracorporeal circuit pathways for lung perfusion -- Hemodynamic performance -- Quality of gas exchange -- Inflammatory cell markers -- Cytokines and cellular adhesion molecules -- Macroscopical and microscopical findings -- Continuous or intermittent lung perfusion with arterial or venous blood -- Lung perfusion and mechanical ventilation -- Pulmonary hemodynamic profile and natriuretic peptides -- Low-frequency mechanical ventilation during cardiopulmonary bypass -- Inhaled carbon monoxide as an experimental therapeutic strategy of lung protection during cardiopulmonary bypass -- Lung perfusion and coronary artery bypass grafting -- Lung perfusion in clinical mitral valve surgery -- Lung perfusion in clinical aortic surgery -- Lung perfusion in clinical heart-lung surgery: congenital heart disease surgery -- Retrograde pulmonary perfusion for pulmonary thromboembolism -- Lung perfusion in clinical heart-lung transplantation -- Principles of pulmonary protection during heart surgery -- Lung perfusion: reflections and perspectives.
  • 2006
    Richard R. Carlton, Arlene M. Adler ; contributors, Eugene D. Frank ... [et al.].
    Status: Not Checked OutLane Catalog Record
  • 2011 ScienceDirect
    2011 ClinicalKey
    [edited by] Anthony Atala ... [et al.].
    Chapter 1. Molecular Organization of Cells / Jon D. Ahlstrom -- Chapter 2. Cell-ECM Interactions in Repair and Regeneration / M. Petreaca, M. Martins-Green -- Chapter 3. Mechanisms of Blastema Formation in Regenerating Amphibian Limbs / David L. Stocum, Nandini Rao -- Chapter 4. The Molecular Circuitry Underlying Pluripotency in Embryonic Stem Cells and iPS Cells / Harvir Singh, Ali H. Brivanlou -- Chapter 5. How Cells Change their Phenotype / Caroline Beth Sangan, David Tosh -- Chapter 6. Scarless Wound Healing / Allison Nauta, Barrett Larson, Michael T. Longaker, H. Peter Lorenz -- Chapter 7. Somatic Cloning and Epigenetic Reprogramming in Mammals / Heiner Niemann, Wilfried A. Kues, Andrea Lucas-Hahn, Joseph W. Carnwath -- Chapter 8. Engineered Proteins for Controlling Gene Expression / Charles A. Gersbach -- Chapter 9. Genetic Approaches in Human Embryonic Stem Cells and their Derivatives: Prospects for Regenerative Medicine / Junfeng Ji, Bonan Zhong, Mickie Bhatia -- Chapter 10. Embryonic Stem Cells: Derivation and Properties / Junying Yu, James A. Thomson -- Chapter 11. Alternative Sources of Human Embryonic Stem Cells / Svetlana Gavrilov, Virginia E. Papaioannou, Donald W. Landry -- Chapter 12. Stem Cells from Amniotic Fluid / Mara Cananzi, Anthony Atala, Paolo de Coppi -- Chapter 13. Induced Pluripotent Stem Cells / Keisuke Okita, Shinya Yamanaka -- Chapter 14. MSCs in Regenerative Medicine / Arnold I. Caplan -- Chapter 15. Multipotent Adult Progenitor Cells / Philip Roelandt, Catherine M. Verfaillie -- Chapter 16. Hematopoietic Stem Cell Properties, Markers, and Therapeutics / Kuanyin K. Lin, Grant A. Challen, Margaret A. Goodell -- Chapter 17. Mesenchymal Stem Cells / Zulma Gazit, Gadi Pelled, Dima Sheyn, Nadav Kimelman, Dan Gazit -- Chapter 18. Cell Therapy of Liver Disease: From Hepatocytes to Stem Cells / Stephen C. Strom, Ewa C.S. Ellis -- Chapter 19. Cardiac Stem Cells: Biology and Therapeutic Applications / Sarah Selem, Konstantinos E. Hatzistergos, Joshua M. Hare -- Chapter 20. Skeletal Muscle Stem Cells / Benjamin D. Cosgrove, Helen M. Blau -- Chapter 21. Stem Cells Derived from Fat / Adam J. Katz, Alexander F. Mericli -- Chapter 22. Peripheral Blood Stem Cells / Zhan Wang, Gunter Schuch, J. Koudy Williams, Shay Soker -- Chapter 23. Islet Cell Therapy and Pancreatic Stem Cells / Juan Domínguez-Bendala, Antonello Pileggi, Camillo Ricordi -- Chapter 24. Regenerative Medicine for Diseases of the Retina / Deepak A. Lamba, Thomas A. Reh -- Chapter 25. Somatic Cells: Growth and Expansion Potential of T Lymphocytes / Rita B. Effros -- Chapter 26. Mechanical Determinants of Tissue Development / Jonathan A. Kluge, Gary G. Leisk, David L. Kaplan -- Chapter 27. Morphogenesis of Bone, Morphogenetic Proteins, and Regenerative Medicine / A.H. Reddi -- Chapter 28. Physical Stress as a Factor in Tissue Growth and Remodeling / Joel D. Boerckel, Christopher V. Gemmiti, Yash M. Kolambkar, Blaise D. Porter, Robert E. Guldberg -- Chapter 29. Intelligent Surfaces for Cell-Sheet Engineering / Takanori Iwata, Masayuki Yamato, Teruo Okano -- Chapter 30. Applications of Nanotechnology for Regenerative Medicine / Benjamin S. Harrison, Sirinrath Sirivisoot -- Chapter 31. Design Principles in Biomaterials and Scaffolds / Hyukjin Lee, Hyun Jung Chung, Tae Gwan Park -- Chapter 32. Natural Origin Materials for Bone Tissue Engineering - Properties, Processing, and Performance / V.M. Correlo, J.M. Oliveira, J.F. Mano, N.M. Neves, R.L. Reis -- Chapter 33. Synthetic Polymers / M.C. Hacker, A.G. Mikos -- Chapter 34. Biological Scaffolds for Regenerative Medicine / Alexander Huber, Stephen F. Badylak -- Chapter 35. Hydrogels in Regenerative Medicine / Justin M. Saul, David F. Williams -- Chapter 36. Surface Modification of Biomaterials / Andrés J. García -- Chapter 37. Histogenesis in Three-dimensional Scaffolds / Melissa K. McHale, Nicole M. Bergmann, Jennifer L. West -- Chapter 38. Biocompatibility and Bioresponse to Biomaterials / James M. Anderson -- Chapter 39. Designing Tunable Artificial Matrices for Stem Cell Culture / Elizabeth F. Irwin, Jacob F. Pollock, David V. Schaffer, Kevin E. Healy -- Chapter 40. Biomineralization and Bone Regeneration / Jiang Hu, Xiaohua Liu, Peter X. Ma -- Chapter 41. Cell Therapy for Blood Substitutes / Shi-Jiang Lu, Qiang Feng, Feng Li, Erin A. Kimbrel, Robert Lanza -- Chapter 42. Articular Cartilage / Lily Jeng, Francois Ng kee Kwong, Myron Spector -- Chapter 43. Myoblast Transplantation in Skeletal Muscles / Daniel Skuk, Jacques P. Tremblay -- Chapter 44. Clinical Islet Transplantation / Juliet A. Emamaullee, Michael McCall, A.M. James Shapiro -- Chapter 45. Fetal Tissues / Ryan P. Dorin, Chester J. Koh -- Chapter 46. Engineering of Large Diameter Vessels / Masood A. Machingal, Saami K. Yazdani, George J. Christ -- Chapter 47. Engineering of Small-Diameter Vessels / Brett C. Isenberg, Chrysanthi Williams, Robert T. Tranquillo -- Chapter 48. Cardiac Tissue / Milica Radisic, Michael V. Sefton -- Chapter 49. Regenerative Medicine in the Cornea / May Griffith, Per Fagerholm, Neil Lagali, Malcolm A. Latorre, Joanne Hackett, Heather Sheardown -- Chapter 50. Alimentary Tract / Richard M. Day -- Chapter 51. Extracorporeal Renal Replacement / Kimberly A. Johnston, H. David Humes -- Chapter 52. Tissue Engineering of the Reproductive System / Stefano Da Sacco, Laura Perin, Roger E. De Filippo -- Chapter 53. Cartilage Tissue Engineering / Qiongyu Guo, Jennifer H. Elisseeff -- Chapter 54. Functional Tissue Engineering of Ligament and Tendon Injuries / Savio L.-Y. Woo, Alejandro J. Almarza, Sinan Karaoglu, Rui Liang, Matthew B. Fisher -- Chapter 55. Central Nervous System / Brian G. Ballios, M. Douglas Baumann, Michael J. Cooke, Molly S. Shoichet -- Chapter 56. Peripheral Nerve Regeneration / Mahesh C. Dodla, Vivek J. Mukhatyar, Ravi V. Bellamkonda -- Chapter 57. Tissue Engineering of Skin / Fiona Wood -- Chapter 58. Regenerative Medicine of the Respiratory Tract / Martin A. Birchall, Sam Janes, Paolo Macchiarini -- Chapter 59. The Digit: Engineering of Phalanges and Small Joints / Makoto Komura, Jaehyun Kim, Anthony Atala, James J. Yoo, Sang Jin Lee -- Chapter 60. Intracorporeal Kidney Support / Jae Hyun Bae, Tamer Aboushwareb, Anthony Atala, James J. Yoo -- Chapter 61. Ethical Considerations / Ronald M. Green -- Chapter 62. US Stem Cell Research Policy / Josephine Johnston -- Chapter 63. Overview of the FDA Regulatory Process / Kevin J. Whittlesey, Mark H. Lee, Jiyoung M. Dang, Maegen Colehour, Judith Arcidiacono, Ellen Lazarus, David S. Kaplan, Donald Fink, Charles N. Durfor, Ashok Batra, Stephen L. Hilbert, Deborah Lavoie Grayeski, Richard McFarland, Celia Witten.
  • 2012 Springer
    Christopher J. Lote.
    The Body Fluids -- Essential Anatomy of the Kidney -- Glomerular Filtration -- Tubular Transport -- The Proximal Tubule -- The Loop of Henle, Distal Tubule and Collecting Duct -- Renal Blood Flow and Glomerular Filtration Rate -- Regulation of Body Fluid Osmolality -- Regulation of Body Fluid Volume -- Renal Regulation of Body Fluid pH -- Renal Control of Body Fluid Potassium Content -- Renal Regulation of Body Calcium, Magnesium and Phosphate -- Summary of the Principal Reabsorptive and Secretory Processes in the Nephron Segments -- Disease Conditions Which Alter Renal Sodium and Water Reabsorption -- Use of Diuretics.
  • 2012 Springer
    Phyllis G. Supino, Jeffrey S. Borer, editors ; foreword by Stephen E. Epstein.
  • 2015 Springer
    Michael K. Pugsley, Michael J. Curtis, editors.
    Preface -- Part 1. An Overview of Safety Pharmacology and its Role in Drug Discovery -- Part 2. The Safety Pharmacology Core Battery -- Part 3. Supplemental Safety Pharmacology -- Part 4. Safety Pharmacology of Biological and Anticancer Pharmaceuticals -- Part 5. Clinical Safety Pharmacology.
  • 2010
    Haas, Marilyn; Moore-Higgs, Giselle J.
    Status: Not Checked OutLane Catalog Record
  • 2010 AccessMedicine
    2010 AccessSurgery
    editor-in-chief, F. Charles Brunicardi ; associate editors, Dana K. Andersen ... [et al.].
    Accreditation council for graduate medical education core competencies -- Systemic response injury and metabolic support -- Fluid and electrolyte management of the surgical patient -- Hemostasis, surgical bleeding, and transfusion -- Shock -- Surgical infections -- Trauma -- Burns -- Wound healing -- Oncology -- Transplantation -- Patient safety -- Physiologic monitoring of the surgical patient -- Minimally invasive surgery, robotics, and natural orifice transluminal endoscopic surgery -- Molecular and genomic surgery -- The skin and subcutaneous tissue -- The breast -- Disorders of the head and neck -- Chest wall, lung, mediastinum, and pleura -- Congenital heart disease -- Acquired heart disease -- Thoracic aneurysms and aortic dissection -- Arterial disease -- Venous and lymphatic disease -- Esophagus and diaphragmatic hernia -- Stomach -- The surgical management of obesity -- Small intestine -- Colon, rectum, and anus -- The appendix -- Liver -- Gallbladder and the extrahepatic biliary system -- Pancreas -- Spleen -- Abdominal wall, omentum, mesentery, and retroperitoneum -- Soft tissue sarcomas -- Inguinal hernias -- Thyroid, parathyroid, and adrenal -- Pediatric surgery -- Urology -- Gynecology -- Neurosurgery -- Orthopedic surgery -- Surgery of the hand and wrist -- Plastic and reconstructive surgery -- Surgical considerations in the elderly -- Anesthesia of the surgical patient -- Ethics, palliative care, and care at the end of life.
  • 2014 ScienceDirect
    edited by Robert Lanza, Robert Langer, Joseph Vacanti.
  • 2000 ScienceDirect
    edited by Robert P. Lanza, Robert Langer, Joseph Vacanti.
    Tissue engineering in perspective -- Introduction to tissue engineering -- Basis of growth and differentiation -- In vitro control of tissue development -- In vivo synthesis of tissues and organs -- Models for tissue engineering -- Biomaterials in tissue engineering -- Transplantation of engineered cells and tissues -- Fetal tissue engineering -- Gene therapy -- Breast -- Cardiovascular system -- Cornea -- Endocrinology and metabolism -- Gastrointestinal system -- Hematopoietic system -- Kidney and genitourinary system -- Musculoskeletal system -- Nervous system -- Periodontal and dental applications -- Skin -- Womb -- Regulatory issues.
    Also available: Print – 2000
  • 2007
    edited by Robert Lanza, Robert Langer, Joseph Vacanti.
    Status: Not Checked OutLane Catalog Record
  • 2015 ScienceDirect
    edited by Martin Wehling, Department of Clinical Pharmacology Mannheim, University of Heidelberg, Mannheim, Germany.
    Principles of Translational Science in Medicine: From Bench to Bedside, Second Edition, provides an update on major achievements in the translation of research into medically relevant results and therapeutics. The book presents a thorough discussion of biomarkers, early human trials, and networking models, and includes institutional and industrial support systems. It also covers algorithms that have influenced all major areas of biomedical research in recent years, resulting in an increasing numbers of new chemical/biological entities (NCEs or NBEs) as shown in FDA statistics. The book is ideal for use as a guide for biomedical scientists to establish a systematic approach to translational medicine.
  • 2010
    edited by Martin Wehling ; foreword by Francesco M. Marincola.
    Status: Not Checked OutLane Catalog Record
    Introduction and definitions -- Target identification and validation -- Biomarkers -- Early clinical trial design -- Pharmaceutical toxicology -- Translational science biostatistics -- Learning by experience : examples of translational processes in the cardiovascular field.
  • 2012 ClinicalKey
    Stuart J. Hutchison.
    Technical issues in vascular ultrasound -- Carotid artery disease and extracranial cerebrovascular disease -- Upper extremity arterial disease -- Arteriovenous fistulas -- Lower extremity arterial disease -- Catheterization-related complications -- The abdominal aorta -- Renal artery disease -- Splanchnic/mesenteric/visceral arteries -- Upper extremity venous disease -- Lower extremity venous disease.
  • v. 1-2, 2009.
    S.J. Flint, V.R. Racaniello, L.W. Enquist, A.M. Skalka.
    Status: Not Checked OutLane Catalog Record
    v. 1. Molecular biology -- v. 2. Pathogenesis and control. v. 1. Foundations -- The infectious cycle -- Genomes and genetics -- Structure -- Attachment and entry -- Synthesis of RNA from RNA templates -- Reverse transcription and integration -- Transcription strategies : DNA templates -- Genome replication strategies : DNA viruses -- Processing of viral pre-mRNA -- Control of translation -- Intracellular trafficking -- Assembly, exit, and maturation -- v. 2. Infection of a susceptible host -- Infection of populations -- Virus offense meets host defense : early actions -- Immune defenses -- Patterns of infection -- Human immunodeficiency virus pathogenesis -- Transformation and oncogenesis -- Vaccines -- Antiviral drugs -- Evolution and emergence.
  • 2006 Springer Protocols
    edited by Franck Pellestor.
  • 2013 CRCnetBASE
    edited by Vincent Béringue, PhD.
    This book contains a selection of chapters aimed to provide a better understanding prion structure and biology. Together these chapters provide an overview of prion biology and underscore some of the challenges we face if we want to understand how this lively pathogen propagates and evolves in mammals. There is also mounting evidence that studying prion biology has a wider relevance due to similarities in the processes of protein misfolding and aggregation between prion disorders and other neurodegenerative disorders such as Alzheimer's, Parkinson's, and Huntington's diseases.
  • 2008 Springer Protocols
    Andrew F. Hill, editor.
    Cell culture models to unravel prion protein function and aberrancies in prion diseases / Katarina Bedecs -- Investigation of PrPc metabolism and function in live cells : methods for studying individual cells and cell populations / Cathryn L. Haigh and David R. Brown -- Immunodetection of PrPsc using western and slot blotting techniques / Hanny Gyllberg and Kajsa Löfgren -- Assaying prions in cell culture : the standard scrapie cell assay (SSCA) and the scrapie cell assay in end point format (SCEPA) / Sukhvir P. Mahal ... [et al.] -- Generation of cell lines propagating infectious prions and the isolation and characterization of cell-derived exosomes / Laura J. Vella and Andrew F. Hill -- Neurotoxicity of prion peptides on cultured cerebellar neurons / Giuseppe D. Ciccotosto, Roberto Cappai, and Anthony R. White -- Understanding the nature of prion diseases using cell-free assays / Victoria A. Lawson -- Methods for conversion of prion protein into amyloid fibrils / Leonid Breydo, Natallia Makarava, and Ilia V. Baskakov -- Amplification of purified prions in vitro / Surachai Supattapone, Nathan R. Deleault, and Judy R. Rees -- Expression and purification of full-length recombinant PrP of high purity / Natallia Makarava and Ilia V. Baskakov -- Analysis of PrP conformation using circular dichroism / Sen Han and Andrew F. Hill -- Effect of copper on the de novo generation of prion protein expressed in Pichia pastoris / Carina Treiber -- Biophysical investigations of the prion protein using electron paramagnetic resonance / Simon C. Drew and Kevin J. Barnham -- Molecular diagnosis of human prion disease / Jonathan D.F. Wadsworth ... [et al.] -- Analysis of endogenous PrPc processing in neuronal and non-neuronal cell lines / Victoria Lewis and Steven J. Collins -- Molecular typing of PrPres in human sporadic CJD brain tissue / Victoria Lewis ... [et al.] -- Transgenic mouse models of prion diseases / Glenn C. Telling -- Quantitiative bioassay of surface-bound prion infectivity / Victoria A. Lawson.
  • 2005 Springer
    T. Kitamoto (ed.).
  • 2006 CRCnetBASE
    Claudio Soto.
    Also available: Print – 2006
  • 2013 Springer
    Wen-Quan Zou, Pierluigi Gambetti, editors.
    Transmissible spongiform encephalopathies (TSE), now broadly known as prion diseases, have been recognized for nearly 300 years in animals and almost 100 years in humans. However, the nature of the transmissible agent had largely remained a mystery until Stanley Prusiner discovered the infectious isoform of the prion protein (PrP), named prion or scrapie PrP (PrPSc), in 1982. The subsequent modern studies with protein chemistry and molecular biology in cell culture, transgenic animals, and cell-free systems, including the revolutionary protein-misfolding cyclic amplification (PMCA), have greatly advanced our understanding of the pathogenesis of prion diseases and facilitated the identification of new prion diseases in animals and humans. In Prions and Prion Diseases, more than 60 leading researchers and clinicians worldwide provide an up-to-date development in many aspects of these unique infectious pathogens and their associated diseases.Volume II features a variety of animal and human prion diseases, including the newly-identified atypical forms of bovine spongiform encephalopathy and scrapie in animals, and variably protease-sensitive prionopathy in humans, prions in the environment, Tau pathology in human prion disease, transmission of the disease by blood transfusion, mammalian and non-mammalian models, conventional and advanced diagnoses, prion-specific antibodies, as well as decontamination of prions and development of therapeutics of prion diseases, such as the application of immunomodulation. This volume provides up-to-date knowledge about the etiology, pathogenesis, classification, histopathological, and clinical aspects of the highly publicized animal and human prion diseases.
  • 2013 Springer
    edited by Wen-Quan Zou and Pierluigi Gambetti.
    Transmissible spongiform encephalopathies (TSE), now broadly known as prion diseases, have been recognized for nearly 300 years in animals and almost 100 years in humans. However, the nature of the transmissible agent had largely remained a mystery until Stanley Prusiner discovered the infectious isoform of the prion protein (PrP), named prion or scrapie PrP (PrPSc), in 1982. The subsequent modern studies with protein chemistry and molecular biology in cell culture, transgenic animals, and cell-free systems, including the revolutionary protein-misfolding cyclic amplification (PMCA), have greatly advanced our understanding of the pathogenesis of prion diseases and facilitated the identification of new prion diseases in animals and humans. In Prions and Prion Diseases, more than 60 leading researchers and clinicians worldwide provide an up-to-date development in many aspects of these unique infectious pathogens and their associated diseases.Volume I highlights the association of the cellular prion protein (PrPC) with copper and zinc, the potential roles of PrPC in Alzheimer's disease and cancers, insoluble PrPC, PMCA, molecular and cellular mechanisms of PrPSc formation and clearance, possible co-factors involved in the conversion of PrPC into PrPSc, infectious and pathogenic forms of PrP, cell biology of prions, prion strains and their interference, as well as yeast prions and their inheritable and structural traits. This unique volume covers history from the high Middle Ages to the TSE era of Daniel Carleton Gajdusek, followed by the prion era of Stanley Prusiner whose extraordinary discovery opened a new chapter in prion research. Volume I will take you through the fascinating chronicle of prions in mammals, yeast, and fungi.
  • 2007
    edited by Beat Hörnlimann ; in collaboration with Detlev Riesner and Hans Kretzschmar.
    Status: Not Checked OutLane Catalog Record
  • 2008
    [edited by] Linda D. Urden, Kathleen M. Stacy, Mary E. Lough.
    Status: Not Checked OutLane Catalog Record
    Ch. 1. Caring for the critically ill patient -- Ch. 2. Ethical and legal issues -- Ch. 3. Patient and family education -- Ch. 4. Psychosocial alterations -- Ch. 5. Sleep alterations -- Ch. 6. Nutritional alterations -- Ch. 7. Gerontologic alterations -- Ch. 8. Pain and pain management -- Ch. 9. Sedation, agitation, and delirium management -- Ch. 10. End-of-life care-- Ch. 11 Cardiovascular assessment and diagnostic procedures -- Ch. 12. Cardiovascular disorders -- Ch. 13. Cardiovascular therapeutic management -- Ch. 14. Pulmonary assessment and diagnostic procedures -- Ch. 15. Pulmonary disorders -- Ch. 16. Pulmonary therapeutic management -- Ch. 17. Neurologic assessment and diagnostic procedures -- Ch. 18. Neurologic disorders and therapeutic management -- Ch. 19. Renal assessment and diagnostic procedures -- Ch. 20. Renal disorders and therapeutic management -- Ch. 21. Gastrointestinal assessment and diagnostic procedures -- Ch. 22. Gastrointestinal disorders and therapeutic management -- Ch. 23. Endocrine assessment and diagnostic procedures -- Ch. 24. Endocrine disorders and therapeutic management -- Ch. 25. Trauma -- Ch. 26. Shock and multiple organ dysfunction syndrome -- Ch 27. Hematologic and oncologic issues.
  • 2006 NLM
    editors, Dean T. Jamison ... [et al.].
  • 2016 Springer
    Eckhard Nagel, Michael Lauerer, editors.
    The gap between a rising demand for health care services on the one side and scarce resources on the other, is leading to a growing pressure on decision-making processes. Hence, prioritization in medicine has become an increasingly important issue for assuring stability of health systems and improving the capability of health care. The present volume addresses normative dimensions of methodological and theoretical approaches, the legal basis behind priority setting as well as international experiences concerning the normative framework and the process of priority setting. It also examines specific criteria for prioritization and discusses economic evaluations. Contributing authors from a broad range of scientific disciplines discuss prioritization within an international dialogue.
  • 2011 WHO
    Background -- Scope, goal, objectives and target audience -- Global burden of NCDs -- Role of research in the implementation of the Global Strategy Action Plan -- Need for a prioritized research agenda for prevention and control of major NCDs to improve public health -- Achievable outcomes through a prioritized research agenda for prevention and control of major NCDs -- Process for the development of the WHO NCD research agenda. Initial phase of development of the WHO NCD research agenda -- Ranking process -- Finalization of WHO NCD research agenda -- Key domains for research. Major NCDs. Cardiovascular disease (CVD) -- Cancer -- Chronic respiratory diseases -- diabetes -- NCD risk factors. Tobacco control -- Nutrition, physical activity and obesity -- Cross-cutting domains. Primary health care approach for prevention and control of NCDs -- Social determinants and NCDs -- Genetics -- Promoting use of research findings to policies and practice for prevention and control of noncommunicable diseases -- Top 20 priority areas for NCD research -- Key elements required for strengthening the research capacity of low- and middle-income countries for implementation of the WHO NCD research agenda. Contents of the compact disc: -- 1. Working papers -- 2. Reports of Meetings to develop the Prioritized NCD research agenda (2008-2010) -- 3. Lists of participants -- 4. List of other contributors and institutions that participated in the process of development and review of the prioritized NCD research agenda.
    Also available: Print – 2011
  • 2011
    Karla F.C. Holloway.
    Status: Not Checked OutLane Catalog Record
    "In Private Bodies, Public Texts, Karla FC Holloway examines instances where medical issues and information that would usually be seen as intimate, private matters are forced into the public sphere. As she demonstrates, the resulting social dramas often play out on the bodies of women and African Americans..."--P. [2] of cover.
  • 2007 Springer
    Ed Hild with Susie Adams.
  • 2008
    Raymond Yee.
    Status: Not Checked OutLane Catalog Record
  • 2015 Cambridge
    Paul Reuwer, Hein Bruinse, Arie Franx.
  • 2005 Springer
    Dirk Husmeier, Richard Dybowski, and Stephen Roberts (eds.).
    A leisurely look at statistical inference / Dirk Husmeier -- Introduction to learning Bayesian networks from data / Dir Husmeier -- A casual view of multi-layer perceptrons as probability models / Richard Dybowski -- Introduction to statistical phylogenetics / Dirk Husmeier -- Detecting recombination in DNA sequence alignments / Dirk Husmeier, Frank Wright -- RNA-based phylogenetic methods / Magnus Rattray, Paul G. Higgs -- Statistical methods in microarray gene expression data analysis / Claus-Dieter Mayer, Chris A. Glasbey -- Inferring genetic regulatory networks from microarray experiments with Bayesian networks / Dirk Husmeier -- Modeling genetic regulatory networks using gene expression profiling and state-space models / Claudia Rangel ... [et al.] -- An anthology of probabilistic models for medical informatics / Richard Dybowski, Stephen Roberts -- Bayesian analysis of population pharmacokinetic/pharmacodynamic models / David J. Lunn -- Assessing the effectiveness of Bayesian feature selection / Ian T. Nabney ... [et al.] -- Bayes consistent classification of EEG data by approximate marginalization / Peter Sykacek, Iead Rezek, and Stephen Roberts -- Ensemble hidden Markov models with extended observation densities for biosignal analysis / Iead Rezek, Stephen Roberts -- A probabilistic network for fusion of data and knowledge in clinical microbiology / Steen Andreassen ... [et al.] -- Software for probability models in medical informatics / Richard Dybowski.
  • María Dolores Ugarte, Ana F. Militino, Alan T. Arnholt.
  • 2008 Springer
    edited by Joyce H.D.M. Westerink ... [et al.].
  • 2009
    Elizabeth Lenz Ponder.
    Status: Not Checked OutLane Catalog Record
  • 2009
    Vincent Bangping Chu.
    The discovery by Cech and coworkers that structured RNA molecules could catalyze specific reactions has revolutionized our understanding of RNA's role and place in the biological machinery of life. The notion of understanding RNA folding from a biophysical perspective means understanding the formation of RNA structure in terms of the basic physical forces at play. This thesis describes the the use of electrostatic and coarse grain simulations and associated experiments to investigate different features of RNA folding. Chapter 1 gives an brief introduction to RNA folding, the primary physical forces that influence its formation, and a review of recent advances in our understanding of structure formation in RNA. Chapters 2 and 3 comprise the next section of the thesis and detail advances in our understanding of electrostatic effects around nucleic acids, a topic of great importance in RNA folding. Specifically, chapter 2 presents the development of a size-modified Poisson-Boltzmann theory to help account for the effects of ionic size while chapter 3 presents a critical assessment of the Poisson-Boltzmann description of electrostatic relaxation in tethered duplex model systems. Chapter 4 highlights a general theoretical framework for understanding the combined effects of electrostatics and junction topology on RNA folding stability and specificity. The last section focuses on the use of coarse grained simulation to understand the role of junction topology in shaping the allowed conformational space of the Transactivation Response (TAR) element from the genome of the Human Immunodeficiency Virus (HIV). Though the last section is not, strictly speaking, a study of RNA folding, understanding RNA conformational motion is of critical importance to the question of structure acquisition in RNAs.
  • 2014 CRCnetBASE
    edited by J. Paulo Sousa e Silva, Ana Cristina Freitas.
    Probiotic bacteria : from science to consumers' benefit / Manuela M. Pintado, Ana M. Gomes, and Ana C. Freitas -- Gastrointestinal tract : microflora and transit aspects / Ana M. Gomes, Manuela M. Pintado, Ana C. Freitas, and J. Paulo Sousa e Silva -- Probiotics and their therapeutic role / Manuela M. Pintado, Ana M. Gomes, and Ana C. Freitas -- Food as vehicles of probiotics / Ana C. Freitas , Dina Rodrigues, Sérgio Sousa, Ana M. Gomes, and Manuela M. Pintado -- Immobilization and microencapsulation of probiotics / Paulo J.C. Costa, Teresa Rocha-Santos, Ana M. Gomes, Manuela M. Pintado, Sérgio Sousa, Maria H. Amaral, J. Paulo Sousa e Silva, and Ana C. Freitas -- Development of probiotic dosage forms / Maria H. Amaral, J. Paulo Sousa e Silva, Paulo J.C. Costa, and Ana M. Gomes -- Guidelines and regulations / J. Paulo Sousa e Silva and Ana M. Gomes.
  • 2011 Springer
    Joshua J. Malago, Jos. F.J.G. Koninkx, R. Marinsek-Logar, editors.
  • 2013 Karger
    volume editors, Alfredo Guarino, Eamonn M.M. Quigley, W. Allan Walker.
    Probiotics : definition and taxonomy 10 years after the FAO/WHO guidelines / L. Morelli -- Intestinal microbiota composition in children / V. Buccigrossi -- Intestinal microbiota composition in adults / V. Robles-Alonso, F. Guarner -- The intestinal microbiota and aging / P.W. O'Toole, P. Brigidi -- Shaping intestinal bacterial community by TLR and NLR signaling / K.S. Kobayashi -- Importance of early microbial colonization for intestinal immune development / P. Brandtzaeg -- Effects of the intestinal microbiota on behavior and brain biochemistry / E. Barrett ... [et al.] -- Relationship between bacterial colonization of human digestive and respiratory tract / S.V. Lynch -- Probiotics in the prevention and treatment of inflammatory bowel diseases in children / B. Pigneur, F.M. Ruemmele -- Functional gastrointestinal disorders in children / F. Indrio, G. Fiezzo -- Functional gastrointestinal disorders in adults / E.M.M. Quigley -- Metabolic syndrome and obesity in children / R. Luoto ... [et al.] -- Metabolic syndrome and obesity : adults / S.E. Power ... [et al.] -- Neonatal necrotizing enterocolitis / J. Neu -- Role of probiotics in allergies / R.B. Canani ... [et al.] -- Probiotics in respiratory infections / E. Bruzzese, A. Lo Vecchio, E. Ruberto -- Are probiotic effects dose-related? / T.J. Patton, S. Guandalini -- Safety of probiotics / I. Hojsak, R. Shamir -- Age-related functional feeding : a novel tool to improve the quality of life / S. Forssten ... [et al.] -- Use of microbes to fight microbes / C. Hill -- What is the future for therapies derived from the microbiome (pharmabiotics)? / G.T. Rijkers ... [et al.].
  • 2011 Springer
    Min-Tze Liong, editor.
  • 2014 CRCnetBASE
    editors, Haruki Kitazawa, Julio Villena, Susana Alvarez.
    "Written by international experts, this book reviews recent, cutting-edge research on the use of immunoregulatory probiotics (immunobiotics) and their bioactive compounds (immunogenics) to prevent and improve health. Each chapter provides critical insight, reviews current research, discusses future perspective, and stimulates discussion. The book also dicsusses novel applications of immunobiotics such as their use in respiratory infections, regulation of the interaction between inflammation and coagulation as well as their effect on hematopoiesis"--Provided by publisher.
  • 2014 CRCnetBASE
    editor, Semih Ötleş.
    1. Probiotics, prebiotics and synbiotics : an introduction / Ravinder Nagpal, Hariom Yadav, Manoj Kumar, Shalini Jain, Yuichiro Yamashiro and Francesco Marotta -- 2. Sources, production and microencapsulation of probiotics / Dima Stefan, Bahrim Gabriela Elena and Iordachescu Gabriela -- 3. Sources and production of prebiotics / Linglin Fu and Yanbo Wang -- 4. Analysis of probiotics and prebiotics / Semih Otles and V. Hazal Ozyurt -- 5. Regulation and guidelines of probiotics and prebiotics / Arturo Anadn̤, Vc̕tor Castellano and Mara̕ Rosa Martn̕ez-Larraąga -- 6. Probiotics and prebiotics in infant nutrition / Dan W. Thomas and Vivien A. Nguyen -- 7. Probiotics and prebiotics in lipid metabolism / Derya Koȧk Yan?k, Ay?e Binnur Erba?c? and Fahrettin G?̲¿? -- 8. Pro- and prebiotics for elderly / Lyra A., Tiihonen K., Lehtinen M.J. and Ouwehand A.C. -- 9. Probiotics and prebiotics in animal nutrition / Mattarelli Paola, Modesto Monica, Sgorbati Barbara and Tacconi Stefano -- 10. Interactions of probiotics and prebiotics with minerals / Corrie M. Whisner and Connie M. Weaver -- 11. Probiotics and prebiotics in obesity and energy metabolism / Ay?e Binnur Erba?c? -- 12. Probiotics and prebiotics and the gut microbiota / Eamonn M.M. Quigley -- 13. Probiotics and prebiotics in immune system protection / Esther Nova, Cristina Abad, Sonia Gm̤ez-Martn̕ez, Tamara Pozo-Rubio and Ascensin̤ Marcos -- 14. Probiotics and prebiotics in pediatric diarrheal disorders / Y. Vandenplas, B. Hauser, E. De Greef, T. Devreker and G. Veereman-Wauters -- 15. Probiotics for gastrointestinal diseases / Hale Akp?nar -- 16. Probiotics and helicobacter pylori / Ruggiero Francavilla, Mari Elena Tripaldi, Massimiliano Praitano, Elena Lionetti and Vito Leonardo Miniello -- 17. Probiotics and prebiotics in infections / Shigeru Kamiya -- 18. Probiotics and prebiotics in cancer prevention / Vijaya K. Gogineni and Lee E. Morrow -- 19. Probiotics and prebiotics in allergy and asthma / Bengt Bjr̲kstň -- 20. Probiotics and prebiotics in Crohn's disease / Susan Mikolaitis, Prachi Chakradeo and Ece A. Mutlu -- 21. Probiotics and prebiotics : new hope for genitourinary health / Sarika Amdekar, Avnish Kumar, Vivek Kumar Shrivastav, Desh Deepak Singh and Vinod Singh -- 22. Genomics of probiotics and prebiotics / Daniel J. O'Sullivan and Prakash M. Halami -- 23. The future of prebiotics and probiotics / Oscar Brunser, Javier A. Bravo and Martin Gotteland.
  • 2009 Springer
    editors, Sonia Michail, Philip M. Sherman.
  • 2013 Springer
    Paolo Gontero, Roger S. Kirby, Culley C. Carson III, editors.
    Urological problems are so common as to represent a significant burden for many primary care physicians and GPs in their everyday practice worldwide. A major concern is how far to go themselves in the diagnosis and treatment of a urological diseases and when to refer the patient for specialist care. Problem Based Urology provides an easy and user-friendly tool to assist in decision making in the treatment of the more common urological problems and the most appropriate timing for referral to specialist care. Within each chapter, one or more flow charts are included to help the reader to formulate the most likely diagnosis on the basis of findings from medical history, examination and investigations, and to start an appropriate first-line treatment or to refer the patient to the specialist where appropriate. This book will appeal to the primary care physician or general practitioner and is an invaluable reference for professionals dealing with common urological complaints.
  • v. 1, 3-4, 1970-.
    Stockholm International Peace Research Institute.
    Status: Not Checked OutLane Catalog Record
    pt. 1. History -- pt. 2. Weapons, military doctrines, national policies -- pt. 3. CBW at the League of Nations and United Nations 1920-69 -- pt. 4. Verification -- pt. 5. International law -- pt. 6. Possible steps to avoid CB warfare.
  • 2009 ClinicalKey
    Neal C. Dalrymple, John R. Leyendecker, Michael Oliphant.
    Elsevier's new Problem Solving in Abdominal Imaging offers you a concise, practical, and instructional approach to your most common imaging questions. It presents basic principles of problem solving to apply to imaging the abdominal and pelvic organs, gastrointestinal tract, and genitourinary tract. Inside, you₂ll find expert guidance on how to accurately read what you see, and how to perform critical techniques including biopsy and percutaneous drainage. User-friendly features, such as tables and boxes, tips, pitfalls, and rules of thumb, place today's best practices at your fingertips. A full-color design, including more than 700 high-quality images, highlights critical elements and compliments the text, to enhance your understanding. Best of all, a bonus CD provides you with an atlas of basic surgical procedures and survival guides for managing musculoskeletal and chest findings encountered on abdominal imaging examinations. Provides problem-solving advice to help you find abnormalities and accurately identify what you see. Presents a section devoted to clinical scenarios - organized by presenting signs or disease processes - covering those you₂re most likely to encounter in daily practice. Includes tips for optimization of the most common advanced imaging techniques used for the abdominal and pelvic regions- with general indications for use and special situations--to help you make the most of each modality. Offers step-by-step guidance that will help you safely approach challenging abdominal interventions, reduce complications, and improve outcomes. Features tables and boxes, tips, pitfalls, and other teaching points for easy reference. Incorporates high-quality images and a full-color design that illuminate important elements.
  • 2006
    Lee Kennedy, Iskandar Idris, Anastasios Gazis.
    Status: Not Checked OutLane Catalog Record
  • 2015 ClinicalKey
    section/associate editors, Stuart Mirvis, Wayne Scott Kubal, Kathirkamanathan Shanmuganathan, Jorge Soto, Joseph S. Yu.
    Strategies for reducing radiation exposure from MDCT in the acute care setting / Aaron D. Sodickson -- Image management in emergency radiology / Martin Lee Gunn -- Craniocerebral trauma / Wayne Scott Kubal -- Non-traumatic brain emergencies / Wayne Scott Kubal -- Face and neck emergencies / Wayne Scott Kubal -- Spinal trauma / Wayne Scott Kubal -- Non-traumatic spine emergencies / Thomas Ptak -- Blunt chest trauma / Lisa A. Miller and Stuart E. Mirvis -- Nonvascular chest emergencies / Jamlik-Omari Johnson, Anuj Tewari and Waqas Shuaib -- Vascular chest emergencies / Sanjeev Bhalla -- Blunt abdominal and retroperitoneal trauma / Kathirkamunathan shanmuganathan -- Imaging of penetrating trauma of the torso and / Kathirkamunathan shanmuganathan -- Non-traumatic abdominal emergencies / Jorge Soto and Kathirkamunathan shanmuganathan -- Upper extremity / Joseph S. Yu -- Lower extremity / Joseph S. Yu -- Pelvis / Joseph S. Yu -- Emergent soft tissue conditions / Joseph S. Yu.
  • 2011 ClinicalKey
    James L. Gutmann, Paul E. Lovdahl.
    The 5th Edition, by James L. Gutmann and Paul Lovdahl, offers updated techniques and an evidence-based approach to the most common procedures performed at chairside. Ideal for both endodontists and general dentists, this thoroughly revised reference combines the precision of quality endodontic care with achievable and pain-free outcomes for the patient. Each chapter has been carefully designed so that you'll quickly grasp the anatomy, the instruments needed, and what procedures should be performed -- all supplemented by boxed clinical case examples and tips. Going beyond problem solving, it also addresses the major issues in diagnostic, anatomic, restorative, periodontic, traumatic, and surgical aspects of tooth retention. Provides a practical, problem-solving approach with new chapters on: radiographic technique and interpretation; impact of pulp disease on the periodontium and vice versa; treatment failure and tooth retention; how to differentiate problems of pulp/periodontium from those that are non-odontogenic in nature; vital pulp therapy; and more.
  • 2008 ClinicalKey
    William B. Morrison, Timothy G. Sanders.
    Elsevier's 'Problem Solving in Radiology' series offers an instructional approach to common imaging questions. In this musculoskeletal volume, readers will find guidance on how to accurately read what they see and how to perform common office procedures, including arthrography and biopsy.
  • 2011 ClinicalKey
    [edited by] Meng Law, Peter M. Som, Thomas P. Naidich.
    A survival guide to solving diagnostic challenges that are particularly problematic in neuroimaging. With a concise, practical, and instructional approach, it helps apply basic principles of problem solving to imaging of the head and interventional neck, brain, and spine. Inside, you'll find expert guidance on how to accurately read what you see, and how to perform critical techniques including biopsy, percutaneous drainage, and tumor ablation. User-friendly features, such as tables and boxes, tips, pitfalls, and rules of thumb, place today's best practices at your fingertips, including protocols for optimizing the most state-of-the-art imaging modalities. A full-color design, including more than 700 high-quality images, highlights critical elements to enhance your understanding. Apply expert tricks of the trade and protocols for optimizing the most state-of-the-art imaging modalities and their clinical applications used for the brain and spine-with general indications for use and special situations. Make the most efficient use of modern imaging modalities including multidetector CT, PET, advanced MR imaging/MR spectroscopy (MRS), diffusion-weighted imaging (DWI), diffusion tensor imaging (DTI), and perfusion weighted imaging (PWI). Successfully perform difficult interventional techniques such as biopsies of the spine and interventional angiography-key techniques for more accurately diagnosing cerebral vascular disease, aneurysm, and blood vessel malformations-as well as percutaneous drainage and tumor ablation. Know what to expect. A dedicated section is organized by the clinical scenarios most likely to be encountered in daily practice, such as neurodegenerative disease, vascular disease, and cancer. Avoid common problems that can lead to an incorrect diagnosis. Tables and boxes with tips, pitfalls, and other teaching points show you what to look for, while problem-solving advice helps you accurately identify what you see-especially those images that could suggest several possible diagnoses. See conditions as they appear in practice thanks to an abundance of case examples and specially designed full-color, high-quality images which complement the text and highlight important elements.
  • 2013 ClinicalKey
    [edited by] Suhny Abbara, Sanjeeva P. Kalva.
    Sect. I. Imaging technique -- sect. II. Anatomy -- sect. III. Devices -- sect. IV. Special situations -- sect. V. Disease entities by anatomic region.
  • 2016 Springer
    Daniel Alicata, Negar Jacobs, Anthony Guerrero, Melissa Piasecki, editors.
    In keeping with the growing emphasis on psychiatry in the medical school curriculum, problem-based learning (PBL) offers students a unique patient-centred, multidisciplinary approach to study and the synthesis of knowledge. The new 2nd edition of Problem-Based Behavioral Science and Psychiatry integrates DSM-5 updates and diagnostic criteria, and is fully consistent with PBL models and methods. Building on the strengths of the popular and widely downloaded 1st edition, the 2nd edition is a clinically robust resource for both the medical and the behavioral science student. Over 40 contributors, many themselves graduates of PBL medical schools, apply problem-based learning methods to specific psychiatric disorders, general clinical issues, and bedrock physician skills such as the intake interview and treatment planning. The book's fictional case vignettes illustrated typical patient scenarios, providing real-world context for content areas, and accompanying case diagrams show the relationships between patient behaviour and underlying neurobiological structures. Each student-friendly section ends with helpful review questions. A sampling of the content areas covered: · Childhood development and brain development. · Major psychiatric illnesses, including personality, mood, anxiety, and psychotic disorders. · Stress, substance abuse, and violence. · Eating, sleep, and sexual disorders. · Coping skills and treatment compliance. · End-of-life care. · PLUS chapters on cultural sensitivity, ethical concerns, and the physician/patient relationship. This book is ideal for first and second year medical students wanting to learn about psychiatry in the exciting context of realistic cases. It also makes an excellent prep/review text for third- and fourth-year medical students preparing for the USMLE Step 1 and 2 exams, as well as being suited to graduate students in psychology or clinical social work. Problem-Based Behavioral Science and Psychiatry encourages lifelong learning and helps build the foundation for a lifelong career.
  • 2008 Springer
    edited by Anthony Guerrero, Melissa Piasecki.
  • 2013 Cambridge
    Eric S. Hsu, Charles Argoff, Katherine E. Galluzzi, Raphael J. Leo, Andrew Dublin.
    Section 1. Headache -- Section 2. Head pain -- Section 3. Neck and shoulder -- Section 4. Upper limb -- Section 5. Thorax -- Section 6. Abdomen and pelvis -- Section 7. Spine -- Section 8. Hip and lower limb -- Section 9. Pain syndromes and special topics -- Index.
  • 2010 ClinicalKey
    Robert G. Carroll.
    Section 1. Nerves and muscles -- section 2. Cardiovascular physiology -- section 3. Renal water and electrolyte balance -- section 4. Hematology -- section 5. Respiration -- section 6. Neurology -- section 7. Gastroenterology -- section 8. Metabolism -- section 9. Endocrinology -- section 10. Reproduction.
  • 2006
    editor, William L. Dewey.
  • 2007 Springer
    edited by Almaz Aldashev, Robert Naeije.
  • v. 1-, 2009- ScienceDirect
  • v. 1-2, 1966-71.
    edited by G. L. Cantoni & David R. Davies.
    Status: Not Checked OutLane Catalog Record
  • Chaya T. Merrill, Anne Elixhauser.
  • 2008 Ovid
    [edited by] Richard S. Irwin ... [et al.].
    Airway management and endotracheal intubation -- Central venous catheterization -- Arterial line placement and care -- Pulmonary artery catherization -- Temporary cardiac pacing -- Cardioversion and defibrillation -- Pericardiocentesis -- Chest tube insertion and care -- Bronchoscopy -- Thoracentesis -- Arterial puncture for blood gas analysis -- Tracheostomy -- Gastrointestinal endoscopy -- Paracentesis and diagnostic peritoneal lavage -- Gastroesophageal balloon tamponade for acute variceal hemorrhage -- Endoscopic placement of feeding tubes -- Cerebrospinal fluid aspiration -- Percutaneous suprapubic cystostomy -- Aspiration of the knee and synovial fluid analysis -- Anesthesia for bedside procedures -- Interventional radiology: drainage techniques -- Cardiopulmonary resuscitation -- Management of pain in the critically ill patient -- Therapeutic paralysis -- Dialysis therapy in the intensive care setting -- Therapeutic apheresis: technical considerations and indications in critical care -- Routine monitoring of critically ill patients -- Indirect calorimetry -- Minimally invasive cardiology -- Neurologic and intracranial pressure monitoring -- Echocardiography in the intensive care unit -- Monitoring gastrointestinal tract function -- Respiratory monitoring during mechanical ventilation.
  • 2011 Springer
    This revised Sixth edition of "Procedures to Investigate Foodborne Illness" is designed to guide public health personnel or teams in any country that investigates reports of alleged foodborne illnesses. It is a companion to another manual published by the IAFP, "Procedures to Investigate Waterborne Illness". These two manuals are based on epidemiologic principles and investigative techniques that have been found effective in determining causal factors of disease incidence. This edition describes procedures to: Plan, prepare, investigate and respond to intentional contaminat.
  • 1968.
    Status: Not Checked OutLane Catalog Record
  • v. 1-2, 1944-48. Google Books
    Fulltext (v. 1947) Google Books
  • 1965-
    edited by Olof Gilland.
    v. 1. Theme 1 : Technical progress in neurological diagnostics -- v. 2. Themes II-IV : The demand for neurological services ; Steroid treatment of neurological disorders ; Free subjects.
  • v. 1-2, 1979.
    editors, D.T. Mason, G.G. Neri Serneri, M.F. Oliver.
    Status: Not Checked OutLane Catalog Record
  • 2008 HighWire
    edited by Francisco Ferná́ndez-Avilés.
  • 1950.
    Status: Not Checked OutLane Catalog Record
  • v. 1-5, 1963.
    Status: Not Checked OutLane Catalog Record
  • v. 1200-, 1990- SPIE
  • v. 3, 1961.
    General editor: Börje Uvnäs.
    Status: Not Checked OutLane Catalog Record
    v. 1. Plenary session. Pharmacological control of release of hormones including antidiabetic drugs.--v. 2. Effects of drugs on synthesis and mobilization of lipids.--v. 3. New aspects of cardiac glycosides.--v. 4. Drugs and membranes.--v. 5. Methods for the study of pharmacological effects at cellular and subcellular levels.--v. 6. Metabolic factors controlling duration of drug action.--v. 7. Modern concepts in the relationship between structure and pharmacological activity.--v. 8. Pharmacological analysis of central nervous action.--v. 9. Bradykinin and vaso-dilating polypeptides. Pharmacology of the lung.--v. 10 Abstracts.
  • v. 1-2, 1954.
    editors: Carlos D. Guerrero, Abner I. Weisman.
    Status: Not Checked OutLane Catalog Record
  • 2005 HighWire
    edited by Gerd Assmann, John Chapman, James Shepherd.
    Also available: Print – 2005
  • 2007 Springer
    Bob van Hilten (editor), Bart Nuttin (editor).
  • 2006 HighWire
    edited by H. Ilkova, T.R. Pedersen, J. Shepherd.
  • 1956
    Status: Not Checked OutLane Catalog Record
  • v. 24-101, 103-164, 166-167, 169-225 ^y 1971-80. SPIE
  • 2008 HighWire
  • v. 1-11, 1966.
    General editor: M. Rocha e Silva.
    Status: Not Checked OutLane Catalog Record
    v. 1. Mode of action of anti-parasitic drugs.--v. 2. Pharmacology of reproduction.--v. 3. Clinical pharmacology.--v. 4. Mechanisms of drug toxicity.--v. 5. The control of growth processes by chemical agents.--v. 6. Drugs in relation to blood coagulation haemostasis and thrombosis.--v. 7. Physico-chemical aspects of drug action.--v. 8. Salt and water balance.--v. 9. Pharmacology of pain.--v. 10. Monoamine oxidas inhibitors: relationship between pharmalogical clinical effects.--v. 11. Immunopharmacology.
  • 2006 CRCnetBASE
    edited by Charles G. Smith, James O'Donnell.
    Overview of the current process of new drug discovery and development / Charles G. Smith and James T. O'Donnell -- Integrated drug product development: from lead candidate selection to life-cycle management / Madhu Pudipeddi, Abu T.M. Serajuddin, and Daniel Mufson -- The impact of combinatorial chemistry on drug discovery / Michael H. Rabinowitz and Nigel Shankley -- High-throughput screening: enabling and influencing the process of drug discovery / Carol Ann Homon and Richard M. Nelson -- Pharmacological and pharmaceutical profiling: new trends / Joanne Bowes ... [et al.] -- Cell-based analysis of drug response using moving optical gradient fields / Jeff M. Hall ... [et al.]. -- Patient-derived primary cells in high-throughput differential antitumor screens: let the patients be the guide / Irwin A. Braude -- The evolving role of the caco-2 cell model to estimate intestinal absorption potential and elucidate transport mechanisms / Jibin Li and Ismael J. Hidalgo -- The promise of metabonomics in drug discovery / Harold J. Kwalwasser and Pauline Gee -- Pharmacogenetics and pharmacogenomics in drug development and regulatory decision-making: report of the first FDA-PWG-PhRMA-druSafe workshop / Lawrence J. Lesko ... [et al.] -- Drugs from molecular targets for CNS and neurodegenerative diseases / William T. Comer and Gönül Veliçelebi -- Safety pharmacology / Jean-Pierre Valentin and Tim G. Hammond -- Nonclinical drug safety assessment / Frederick E. Reno -- Preclinical genotoxicity testing: past, present and future / Richard H.C. San -- The need for animals in biomedical research / Charles G. Smith -- Defining the actual research approach to the new drug substance / Charles G. Smith -- Pharmacokinetics: pharmacodynamics in new drug development / Sarfaraz K. Niazi -- Pharmaceutics and compounding issues in new drug development and marketing / Loyd V. Allen -- Late stage and process development activities / Charles G. Smith -- Contract research organizations: role and function in new drug development / F. Richard Nichol -- The front lines of clinical research: the industry / Lori Nesbitt -- Horizons for cancer chemotherapy (and nonchemotherapy) / Daniel D. Von Hoff -- Human immunodeficiency virus/acquired immune deficiency syndrome: clinical testing challenges / Vincent Idemyor -- Common technical document: the changing face of the new drug application / Justina A. Molzon -- Electronic publishing / Heather L. Wallace -- The important role of pharmacists in a complex risk-management system: managing the risks from medical product use by focusing on patient education, monitoring, and adverse event reporting / Justina A. Molzon -- Liability, litigation, and lessons in new drug development / James T. O'Donnell -- Problems in the nondrug marketplace / Stephen Barrett -- Patents and new product development in the pharmaceutical and biotechnology industries / Henry Grabowski -- The pharmaceutical revolution: drug discovery and development / John C. Somberg -- The discovery of Rituxan / Mitchell E. Reff -- Funding the birth of a drug: lessons from the sell side / Howard E. Greene -- Innovations for the drug development pathway: what is needed now / Janet Woodcock -- Managing R & D uncertainty and maximizing the commercial potential of pharmaceutical compounds using the dynamic modeling framework / Mark Paich ... [et al.].
  • 2007 CRCnetBASE
    edited by Abhinav A. Shukla, Mark R. Etzel, Shishir Gadam.
    Harvest of a therapeutic protein product from high cell density fermentation broths : principles and case study / Elisabeth Russell, Alice Wang, and Anurag S. Rathore -- Expanded bed adsorption for capture from crude solution / Alan Sonnenfeld and Jorg Thommes -- Product recovery by high-gradient magnetic fishing / Matthias Franzreb ... [et al.] -- Protein refolding and scale up / Cynthia Cowgill, Asuman G. Ozturk, and Richard St. John -- Bulk protein crystallization, principles and methods / Mark R. Etzel -- Modes of preparative chromatography / Abhinav A. Shukla and Yinges Yigzaw -- Screening of chromatographic stationary phases / Abhinav A. Shukla and Xuejun Sean Han -- A priori prediction of chromatographic separations from protein structure data / Asif Ladiwala, Curt M. Breneman, and Steven M. Cramer -- Membrane chromatography : analysis of breakthrough curves and viral clearance / Mark R. Etzel and William T. Riordan -- Ultrafiltration process design and implementation / Herb Lutz and Bala Raghunath -- Virus filtration process design and implementation / Michael W. Phillips ... [et al.] -- Product recovery from transgenic sources / Chenming (Mike) Zhang and Kevin E. Van Cott -- Analytical strategy for biopharmaceutical development / Drew N. Kelner and Mahesh K. Bhalgat -- Evaluation of viral clearance in purification processes / Amitava Kundu and Karl Reindel -- Advances in viral clearance / Kurt Brorson -- Protein A affinity chromatography for capture and purification of monoclonal antibodies and Fc-fusion proteins: practical considerations for process development / Sanchayita Ghose, Thomas McNerney, and Brian Hubbard -- Polishing methods for monoclonal IgG purification / Pete Gagnon -- Making changes to a biopharmaceutical manufacturing process during development and commercial manufacturing : the REMICADE story / Peter W. Wojciechowski ... [et al.] -- Linear scale-up of ultrafiltration of high viscosity process streams / Christopher Daniels ... [et al.] -- A membrane chromatography application : a rapid, high capacity gene therapy vector purification tool / Ajay R. Lajmi, Robert Kutner, and Jakob Reiser.
  • Lawrence E. Hunter.
    In the beginning -- Evolution -- A little bit of chemistry -- The structure and function of bacteria -- Biological macromolecules -- Eukaryotes -- Multicellular organisms and development -- Anatomy, physiology, and systems biology -- Disease and its treatment -- Molecular biotechnology -- Molecular bioethics.
  • 2007/2008
    Seonhi Kim.
    Status: Not Checked OutLane Catalog Record
  • 2015 ScienceDirect
    Vivekkumar K. Redasani, Sanjay B. Bari.
    Ch. 1. Introduction -- Ch. 2. Concept of prodrug -- Ch. 3. Types of prodrugs -- Ch. 4. Approaches for prodrugs -- Ch. 5. Applications -- Ch. 6. Role in drug discovery -- Ch. 7. Work reported -- Conclusion.
  • 2007 Springer
    Valentino J. Stella ... [et al.], editors.
  • 2006 CRCnetBASE
    William L. Hochfeld.
  • 2011
    William Chiyao Yang.
    The overall objective of this thesis was to produce and characterize recombinant transducible (able to enter cells) transcription factors (TFs). TFs are complex, difficult-to-make proteins that regulate gene expression and cell fate. Thus, we wanted to deliver transducible TFs exogenously to cells to change gene expression and alter cell fate. Ectopic expression of a set of pluripotency-regulating TFs (Oct4, Sox2, Klf4, cMyc, Lin28, and Nanog) using viral vectors can reprogram adult cells to pluripotency. The resultant cells are pluripotent and can self-renew indefinitely, just like embryonic stem cells. These induced pluripotent stem cells (iPSCs) hold enormous potential for patient-specific cell-based therapies and disease models. However, viruses integrate foreign DNA into the host cell genome, causing insertional mutagenesis and genomic instability which renders the cell unsuitable for clinical use. A non-viral method of iPSC generation is necessary in order to bring iPSCs from the bench to bedside. Direct delivery of the TFs as recombinant proteins offers one avenue for non-viral iPSC generation. Conjugation of an arginine-rich protein transduction domain (PTD) to the TF cargo enables intracellular delivery of the exogenously administered fusion protein. The overall goal of this multi-investigator project was to develop a protein-based method for iPSC generation using purified recombinant TFs fused with a nona-arginine (R9) PTD. The first step is to efficiently produce TF proteins that are active in controlling downstream target gene expression. Thus, my thesis focuses on the upstream portion of the overall project, the production and characterization of the recombinant transducible TFs. TFs are difficult to produce in live cell cultures due to aggregation and product toxicity. Thus, we used E. coli cell-free protein synthesis (CFPS) to produce these transducible TFs. CFPS decouples protein synthesis from maintenance of host cell health to permit production of toxic proteins and slows the translation rate to favor proper protein folding. Using CFPS, we made R9-Oct4, R9-Sox2, R9-Klf4, R9-cMyc, R9-Lin28, and R9-Nanog. Taking advantage of the flexibility offered by CFPS, we addressed protein truncation and solubility problems to produce full-length and soluble TFs. We then showed that R9-Oct4, R9-Sox2, and R9-Nanog exhibit specific binding to their respective consensus DNA sequence probes. We also demonstrated that R9-Nanog enters cells and that R9-Sox2 both enters the cell and upregulates the expression of its downstream gene targets. Though we made full-length and soluble TFs, the soluble yields were still low. The open nature of CFPS allows us to perturb protein production conditions by adding excipients to enhance soluble production. However, it is often not clear if the excipients facilitate the production of fully functional proteins. Therefore, we developed a filter microplate assay for quantitative analysis of DNA binding (one function of the TFs) to potentially be used as a screen for identifying protein production conditions that enable production of soluble and active protein. We validated this assay by showing specific DNA binding, affinity, and capacity for CFPS-produced Sox2 and Nanog. We also attempted to improve soluble transducible TF production in live E. coli cultures using a solubility fusion partner, the first domain of the E. coli initiation factor 2 (IF2D1). IF2D1 improved both total and soluble expression of the IF2D1-TF-R9 fusion proteins, but when the IF2D1 was removed, the TF-R9 cargo became insoluble even though the un-cleaved IF2D1-TF-R9 exhibited the expected DNA binding activity. Unfortunately, un-cleaved IF2D1-Oct4-R9 and IF2D1-Sox2-R9 were not fully bioactive when administered to cells. They only influenced the expression of a subset of their downstream target genes, suggesting that while the IF2D1 solubility partner improved soluble TF expression, it did not yield functional TFs. In parallel, we sought to quantify the intracellular delivery of the transducible TFs. Using radioactively labeled R9-Sox2 and Sox2, we showed that both proteins bind equally well to the outside of target fibroblast cells, but only R9-Sox2 enters the cell. This observation was confirmed using immunohistochemistry to visualize protein delivery as well as quantitative PCR to show that R9-Sox2 influences intracellular gene expression while Sox2 does not. The prevailing hypothesis for PTD-mediated cellular entry is fluid phase endocytosis of the cationic PTD fusion proteins bound on the cell surface. Our results provide evidence to support a competing hypothesis in the literature that binding of the PTD fusion to the cell surface is not sufficient for internalization. Originally, we sought to quantify both the intracellular delivery and localization of 14C leucine-labeled R9-Sox2. However, we reached the detection limit of 14C leucine radiation at the whole cell level. Thus, an alternative quantification method was necessary to measure endosomal entrapment, cytoplasmic delivery, and nuclear localization. We developed a sandwich enzyme-linked immunosorbent assay (ELISA) for this purpose. We hypothesized that picomolar sensitivity was required to detect the low levels of R9-Sox2 delivered to the nucleus. We identified an antibody pair that was able to detect picomolar concentrations of purified R9-Sox2. But, this sandwich ELISA exhibited a high degree of non-specific binding when it was performed in a mock experimental context by spiking known amounts of purified R9-Sox2 into cytoplasmic and nuclear lysates. We troubleshot non-specific binding by exploring various antibodies and assay conditions, but were not able to reduce non-specific binding to the level that enabled picomolar detection. However, we did identify a condition that enabled nanomolar detection of R9-Sox2 in undiluted cytoplasmic and nuclear lysates, a nearly 40-fold improvement over the sensitivity of 14C leucine radiation. In summary, this work described the production and characterization of recombinant transducible TFs to support a protein-based approach for iPSC generation. Using CPFS, we developed a platform for producing recombinant TFs as well as tools and methods for characterizing TF activity and intracellular localization. These studies also displayed the flexibility and potential offered by CFPS for engineering and producing complex fusion proteins.
  • 2011
    John Patrick Welsh.
    The Swartz lab has put much effort into understanding the underlying principles of E. coli-based cell-free protein synthesis (CFPS), and the technology has developed into a scalable, affordable platform for producing a wide range of protein targets. Key breakthroughs have included activating central metabolism, stabilization of critical amino acids, controlling the redox environment to produce proteins containing disulfide bonds, and using scale-up technologies to produce proteins at milligram quantities. My work has sought to expand this CFPS technology for producing valuable and complex eukaryotic protein targets by manipulating and optimizing the folding of these proteins in the heterologous CFPS environment. Furthermore, I have sought to apply these advances to specific applications of interest. By modifying a key molecular chaperone native to the eukaryotic endoplasmic reticulum (ER), the Hsp70-family chaperone, BiP, soluble production was increased in CFPS reactions for specific proteins normally secreted through this organelle, namely those from the immunoglobulin superfamily which includes antibodies, T-cell receptors, and many membrane receptors. First, the functional properties of BiP were compared to that of the E. coli Hsp70, DnaK. A fusion protein was then constructed between BiP and the ribosome-binding portion of the E. coli protein, trigger factor, to localize BiP to translating ribosomes. This replicated the native function of BiP, which provides co-translational folding assistance to nascent polypeptides. After verifying its bioactivity, this fusion protein was utilized in CFPS reactions to indicate that the chaperone functions of BiP are specific to proteins normally secreted through the eukaryotic ER, whereas DnaK demonstrates a more general chaperone mechanism. Since the discovery that somatic cells could be reprogrammed back to a pluripotent state through the viral expression of a specific set of transcription factors, there has been great interest in reprogramming using a safer and more clinically relevant protein-based approach. Production of these transcription factor proteins was greatly increased by fusing them to the C-terminus of the solubility partner, IF2 domain 1 (IF2D1). While the fusions provided marginal benefit in molar yields using a CFPS approach, in vivo E. coli expression produced the transcription factors in soluble form. The fusion proteins could be purified in milligram quantities from liter shake-flask cultures, whereas essentially no soluble protein accumulated without the fusion partner. The transcription factor fusions bound specifically to their consensus DNA sequences and partially activated some of their downstream gene targets. Another application utilizing CFPS technology is an enhanced luciferase mutant from the marine copepod, Gaussia princeps (GLuc). GLuc is both the smallest and brightest known luciferase, and previous work from our lab demonstrated that this protein could be produced at higher volumetric yields and specific activities in CFPS compared to conventional protein expression systems. By mutating key residues in the Gaussia luciferase sequence, the luminescence half-life was shown to increase over ten-fold while maintaining the initial specific activity of the wild-type. This improved mutant provides a valuable imaging agent to use in fusions and bioconjugates with other proteins such as those that recognize cell surface markers on cancer cells. In a final application, influenza vaccines were produced using CFPS by isolating specific fragments of the protein hemagglutinin (HA), a viral surface protein. Specific mutations as well as a C-terminal trimerization domain were critical for producing this protein fragment in both its monomeric and native trimeric forms. By using the CFPS platform to incorporate non-natural amino acids (nnAAs) with alkyne functional groups, the HA proteins were covalently 'clicked' to virus-like particles (VLPs) that had surface exposed nnAAs with azide functionality. The VLPs provide an immunogenic delivery platform that efficiently traffics to lymph nodes and allows for co-attachment of other adjuvants in addition to the primary HA antigen. This vaccine platform was characterized and tested in mouse models and compared to both a standard influenza vaccine as well as free HA protein fragments. In summary, CFPS is a valuable and robust method of protein production for a variety of targets. My thesis has sought to use this platform as a means to better understand folding pathways of complex, eukaryotic proteins and improve production of these proteins. To this end, CFPS has been shown to be a valuable method for elucidating and manipulating chaperone function, producing difficult proteins with enhanced function, and as a platform to produce novel vaccines.
  • 2008 Springer
    Bruce Maxwell.
  • 2011 Ovid
    Signs & symptoms (A-Z) -- Appendices -- Selected signs & symptoms -- Potential agents of bioterrorism -- Adverse effects associated with herbs -- Obtaining a health history -- Guide to laboratory test results.
    Also available: Print – 2011
  • 2007 Ovid
    Signs and symptoms -- Selected signs and symptoms -- Potential agents of bioterrorism -- Common signs and symptoms associated with herbs -- Obtaining a health history -- Guide to laboratory test results.
    Also available: Print – 2007
  • 2016
    Kathleen Koernig Blais, Ed. D., RN, Florida International University, Janice S. Hayes, PhD, RN, University of Northern Colorado.
    Status: Not Checked OutLane Catalog Record
    Beginning the journey -- Socialization to professional nursing roles -- Historical foundations of professional nursing -- Ethical foundations of professional nursing -- Legal foundations of professional nursing -- Knowledge development in nursing -- The nurse as health promoter and care provider -- The nurse as learner and teacher -- The nurse as leader and manager -- The nurse's role in evidence-based health care -- The nurse's role in quality and safety -- The nurse's role as political advocate -- The nurse as colleague and collaborator -- Communicating effectively -- Managing change -- Technology and informatics -- Nursing in an evolving health care delivery system -- Providing care in home and community -- Global health -- Dimensions of holistic health care -- Nursing in a culturally diverse world -- Nursing in a spiritually diverse world -- Nursing in a culture of violence -- Advanced nursing education and practice -- The future of nursing.
  • Google Books
    Also available: Print – 1879-
  • 2015 Springer
    Douglas E. Mitchell, Robert K. Ream, editors.
    At the center of this book is the complex and perplexing question of how to design professional preparation programs, organizational management practices, public policy systems and robust professional associations committed to and capable of, maintaining confidence, trust and the other hallmarks of responsible professionalism. To do this, we need to rebuild our understanding of professional responsibility from the ground up. We describe how individuals might be prepared to engage in responsible professional service delivery, examine promising options for the reform of professional service systems and finally, outline a reform strategy for improving practice in education and medicine ? two essential public services. The nexus of the reform problem in professionalism is establishing a more robust and effective working relationship between teachers and their students; between health care professionals and their patients and between educators and health professionals. Professionalism means acceptance of professional responsibility for student and patient outcomes ? not just acceptance of responsibility for technical expertise, but commitment to the social norms of the profession, including trustworthiness and responsibility for client wellbeing. In the past, it may have been sufficient to assume that adequate knowledge can be shaped into standards of professional practice. Today, it is clear that we must take careful account of the ways in which practicing professionals develop, internalize and sustain professionalism during their training, along with the ways in which this commitment to professionalism may be undermined by the regulatory, fiscal, technological, political and emotional incentive systems that impinge on professional workplaces and professional employment systems.
  • 2012
    edited by Stephen B. Roberts in consultation with D.W. Donovan and others.
    Status: Not Checked OutLane Catalog Record
    Part I. Theology of spiritual/pastoral care : -- 1. Creating a personal theology to do spiritual/pastoral care -- 2. Creating a personal theology to do spiritual/pastoral care -- Part II. The process of spiritual/pastoral care : -- 3. The process of spiritual/pastoral care: a general theory for providing spiritual/pastoral care using palliative care as a paradigm -- 4. Assessments -- 5. Creating and implementing a spiritual/pastoral care plan -- 6. Chaplains and charting -- 7. Foundational listening and responding skills -- 8. Prayer and ritual -- 9. Counseling and interventions -- 10. Inspiring hope: confronting fear, guilt and shame in spiritual/pastoral care -- 11. Life review -- 12. End-of-life chaplaincy care -- 13. Ethics and the care of the sick: an overview for professional chaplains and other spiritual/pastoral care providers -- 14. Spirituality groups -- 15. Spiritual care of staff -- 16. Gender issues in pastoral care -- 17. Working with community religious resources -- 18. Transdisciplinary relationships -- Part III. Spiritual/pastoral care with special populations : -- 19. Spiritual/pastoral care in worlds beyond: ministry to international and immigrant patients -- 20. Pediatric chaplancy -- 21. Behavioral health -- 22. Gay, lesbian, bisexual, and transgendered (GLBT) people -- 23. Spiritual/pastoral care with people with disabilities and their families -- 24. Chronic illness -- 25. Complicated grief: exploring arresting grief and survival grief in spiritual/pastoral care -- Part IV. The infrastructure of spiritual/pastoral care : -- 26. Strategic planning: a basis for all infrastructure development and growth within spiritual/pastoral care -- 27. Outcome oriented chaplaincy: intentional caring -- 28. Referral plans: developing and implementing tactical plans regarding who chaplains should visit -- 29. Quality improvement: A chaplaincy priority -- 30. Health care chaplaincy as a research-informed profession -- 31. Cultural Competencies -- 32. Sacred space -- 33. Blessings of a mixed population: institutional prayer in multifaith communities
  • 2008
    Laura Weiss Roberts, Jinger G. Hoop.
    Status: Not Checked OutLane Catalog Record
  • 2015 Springer
    Laura Weiss Roberts, Daryn Reicherter, editors.
    Professionalism and Ethics in Medicine: A Study Guide for Physicians and Physicians-in-Training is a unique self-study guide for practitioners and trainees covering the core competency areas of professionalism, ethics, and cultural sensitivity. This novel title presents real-world dilemmas encountered across the specialties of medicine, offering guidance and relevant information to assist physicians, residents, and medical students in their decision-making. The text is divided into two parts: Foundations and Questions with Answers. The first part provides a substantive foundation of knowledge in the principles, scholarship, policy guidelines, and decision-making strategies of the modern health professions. The second part assists practitioners and trainees in preparing for the complex issues that arise each day in the settings where health professionals work and train ? clinics, research centers, educational contexts, and communities. Developed by renowned leaders in a broad range of clinical fields, Professionalism and Ethics in Medicine: A Study Guide for Physicians and Physicians-in-Training is a major, invaluable contribution to the literature and an indispensable reference for clinicians at all levels.
  • 2011 Springer
    Charles S. Cox Jr., editor.
  • 2012 Springer Protocols
    edited by Kimberly A. Mace, Kristin M. Braun.
    Isolation of satellite cells from single muscle fibers from young, aged, or dystrophic muscles / Valentina Di Foggia and Lesley Robson -- Terminal differentiation of human epidermal stem cells on micro-patterned substrates / John T. Connelly -- Isolation, culture, and potentiality assessment of lung alveolar stem cells / Feride Oeztuerk-Winder and Juan-Jose Ventura -- Three-dimensional in vitro culture techniques for mesenchymal stem cells / Fatima A. Saleh [and others] -- Isolation of adult stem cells and their differentiation to Schwann cells / Cristina Mantovani, Giorgio Terenghi, and Susan G. Shawcross -- Functional purification of human and mouse mammary stem cells / Daniela Tosoni, Pier Paolo Di Fiore, and Salvatore Pece -- Isolation and expansion of endothelial progenitor cells derived from mouse embryonic stem cells / S. Bahram Bahrami, Mandana Veiseh, and Nancy J. Boudreau -- Transcriptome analysis of Drosophila neural stem cells / Katrina S. Gold and Andrea H. Brand -- Live imaging for studying asymmetric cell division in the C. elegans embryo / Alexia Rabilotta, Rana Amini, and Jean-Claude Labbé -- Tol2-mediated gene transfer and in ovo electroporation of the otic placode : a powerful and versatile approach for investigating embryonic development and regeneration of the chicken inner ear / Stephen Freeman [and others] -- Labeling primitive myeloid progenitor cells in Xenopus / Ricardo Costa [and others] -- Identification of oocyte progenitor cells in the zebrafish ovary / Bruce W. Draper -- FACS analysis of the planarian stem cell compartment as a tool to understand regenerative mechanisms / Belen Tejada Romero, Deborah J. Evans, and A. Aziz Aboobaker -- Clonal and lineage analysis of melanocyte stem cells and their progeny in the zebrafish / Robert C. Tryon and Stephen L. Johnson -- Reconstitution of the central nervous system during salamander tail regeneration from the implanted neurospheres / Levan Mchedlishvili, Vladimir Mazurov, and Elly M. Tanaka -- Following the fate of neural progenitors by homotopic/homochronic grafts in Xenopus embryos / Raphaël Thuret and Nancy Papalopulu -- Analyzing the angiogenic potential of Gr-1CD11b⁺ immature myeloid cells from murine wounds / Elahe Mahdipour and Kimberly A. Mace -- In vivo imaging of hematopoietic stem cells in the bone marrow niche / Oliver Barrett, Roberta Sottocornola, and Cristina Lo Celso -- Characterizing the phenotype of murine epidermal progenitor cells : complementary whole-mount visualization and flow cytometry strategies / Korinna D. Henseleit [and others] -- Murine aggregation chimeras and wholemount imaging in airway stem cell biology / Ian R. Rosewell and Adam Giangreco -- Live imaging of primitive endoderm precursors in the mouse blastocyst / Joanna B. Grabarek and Berenika Plusa -- Utilizing DNA mutations to trace epithelial cell lineages in human tissues / Sebastian Zeki, Trevor A. Graham, and Stuart A.C. McDonald -- NF-Ya protein delivery as a tool for hematopoietic progenitor cell expansion / Alevtina D. Domashenko, Susan Wiener, and Stephen G. Emerson -- Exploring the link between human embryonic stem cell organization and fate using tension-calibrated extracellular matrix functionalized polyacrylamide gels / Johnathon N. Lakins, Andrew R. Chin, and Valerie M. Weaver -- Isolation of circulating angiogenic cells / Erin E. Vaughan and Timothy O'Brien -- Methods for characterization/manipulation of human corneal stem cells and their applications in regenerative medicine / Francesca Corradini [and others] -- ALDH as a marker for enriching tumorigenic human colonic stem cells / Anitha Shenoy, Elizabeth Butterworth, and Emina H. Huang -- Protocols for investigating microRNA functions in human neural progenitor cells / Sandra Almeida [and others].
  • 2008 Springer
    O. Conneely, C. Otto, editors.
  • 2015 Springer
    Angelo Sghirlanzoin, Giuseppe Lauria and Luisa Chiapparini, editors.
    Foreword -- Preface -- Vascular Diseases: Ischemic Stroke -- Vascular Diseases: Cerebral Hemorrhage -- Inflammatory Diseases of the Cerebral Arteries -- Trauma of the Central Nervous System -- Coma -- Sleep Disorders -- Viral Infections of the Nervous System -- Bacterial, Fungal and Parasitic Infections of the Central Nervous System -- Leprosy -- Prion Diseases -- Myelin Disorders: Multiple Sclerosis -- Myelin Disorders: Devic's Syndrome -- Myelin Disorders: Post-Infectious Neurological Syndromes (PINS) -- Leukodystrophies -- Antibody-Mediated Encephalitis -- Dementias -- Intellectual Disability -- Toxic and Deficiency Encephalopathies -- Inborn Errors of Metabolism -- Mitochondrial Disorders -- Disorders of Upper and Lower Motor Neurons -- Headaches -- Disorders of Cerebrospinal Fluid Circulation -- Epilepsy and Myoclonus -- Neoplastic Disorders -- Neurofibromatosis Type 1 and Type2.-Paraneoplastic Neurological Syndromes -- Extrapyramidal Diseases: Parkinson's Disease -- Extrapyramidal Diseases: Atypical Parkinsonisms -- Extrapyramidal Diseases: Huntington's Disease -- Extrapyramidal Diseases: Hyperkinetic Movement Disorders -- Tics and Tourette Syndrome -- Extrapyramidal Diseases: Essential Tremor -- Extrapyramidal Diseases: Dystonia -- Ataxias and Cerebellar Degenerations -- Disorders of Peripheral Nerves -- Disorders of Autonomic Nervous System -- Autoimmune Ion Channel Disorders of the Peripheral Nervous System -- Muscular Dystrophies -- Inflammatory Myophaties -- Pain and Related Syndromes.
  • 2015
    Jared Call, Bruce Kariya.
    The Program Access Index (PAI) estimates CalFresh utilization among low-income individuals. The United States Department of Agriculture (USDA) produces an annual state-by-state PAI. The PAI provided in this report is a county-level analysis modeled on the USDA methodology. The PAI can help illuminate county-level differences in CalFresh utilization by comparing the number of individuals who meet select CalFresh eligibility criteria and the number of individuals who actually receive CalFresh benefits.
  • 1969
    edited by Herbert C. Schulberg, Alan Sheldon [and] Frank Baker.
    Status: Not Checked OutLane Catalog Record
  • ScienceDirect
    Fulltext (v. 6) ScienceDirect
    volume editors, Mark P. Mattson, Steven Estus, Vivek Rangnekar.
    v. 1. Cellular and molecular mechanisms -- v. 2. Role in disease, pathogenesis, and prevention.
    Also available: Print – v. 1-2, 2001.
  • 2008 Springer
    [edited by] Roya Khosravi-Far, Eileen White.
    Cell death : history and future / Zahra Zakeri and Richard A. Lockshin -- Caspase mechanisms / Guy S. Salvesen and Stefan J. Riedl -- The mitochondrial death pathway / Anas Chalah and Roya Khosravi-Far -- Apoptotic pathways in tumor progression and therapy / Armelle Melet ... [et al.] -- Therapeutic targeting of death pathways in cancer : mechanisms for activating cell death in cancer cells / Ting-Ting Tan and Eileen White -- Overcoming resistance to apoptosis in cnacer therapy / Peter Hersey, Xu Dong Zhang, and Nizar Mhaidat -- Trail receptors : targets for cancer therapy / Robin C. Humphreys and Wendy Halpern -- Rational design of therapeutics targeting the BCL-2 family : are some cancer cells primed for death but waiting for a final push? / Victoria Del Gaizo Moore and Anthony Letai -- Autophagy and tumor suppression : recent advancesin understanding the link between autophagic cell death pathways and tumor development / Shani Bialik and Adi Kimchi -- Regulation of programmed cell death by the P53 pathway / Kageaki Kuribayashi and Wafik S. El-Deiry -- Regulation of programmed cell death by NF-[kappa]B and its role in tumorigenesis and therapy / Yongjun Fan ... [et al.] -- Targeting proteasomes as therapy in multiple myeloma / Dharminer Chauhan, Teru Hideshima, and Kenneth C. Anderson -- Histone deacetylase inhibitors : mechanisms and clinical significance in cancer : HDAC inhibitor-induced apoptosis / Sharmila Shankar and Rakesh K. Srivastava -- RNA interference and cancer : endogenous pathways and therapeutic approaches / Derek M. Dykxhoorn, Dipanjan Chowdhury, and Judy Lieberman -- Cancer stem cells and impaired apoptosis / Zainab Jagani and Roya Khosravi-Far.
    Also available: Print – 2008
  • 2008 ScienceDirect
    edited by Roya Khosravi-Far, Zahra Zakeri, Richard A. Lockshin and Mauro Piacentini.
    Also available: Print – 2008
  • 2008 ScienceDirect
    edited by Roya Khosravi-Far, Zahra Zakeri, Richard A. Lockshin and Mauro Piacentini.
    Also available: Print – 2008
  • 2013 Springer
    Fred H. Gage, Yves Christen, editors.
    The recent advances in Programming Somatic Cell (PSC) including induced Pluripotent Stem Cells (iPS) and Induced Neuronal phenotypes (iN), has changed the experimental landscape and opened new possibilities. The advances in PSC have provided an important tool for the study of human neuronal function as well as neurodegenerative and neurodevelopmental diseases in live human neurons in a controlled environment. For example, reprogramming cells from patients with neurological diseases allows the study of molecular pathways particular to specific subtypes of neurons such as dopaminergic neurons in Parkinson.s Disease, Motor neurons for Amyolateral Sclerosis or myelin for Multiple Sclerosis. In addition, because PSC technology allows for the study of human neurons during development, disease-specific pathways can be investigated prior to and during disease onset. Detecting disease-specific molecular signatures in live human brain cells, opens possibilities for early intervention therapies and new diagnostic tools. Importantly, it is now feasible to obtain gene expression profiles from neurons that capture the genetic uniqueness of each patient. Importantly, once the neurological neural phenotype is detected in vitro, the so-called "disease-in-a-dish" approach allows for the screening of drugs that can ameliorate the disease-specific phenotype. New therapeutic drugs could either act on generalized pathways in all patients or be patient-specific and used in a personalized medicine approach. However, there are a number of pressing issues that need to be addressed and resolved before PSC technology can be extensively used for clinically relevant modeling of neurological diseases.
  • 2007 ProQuest Safari
    Toby Segaran.
  • 2012 CRCnetBASE
    Michael F. Lawrence, John Verzani.
    "Preface About this book Two common types of user interfaces in statistical computing are the command line interface (CLI) and the graphical user interface (GUI). The usual CLI consists of a textual console in which the user types a sequence of commands at a prompt, and the output of the commands is printed to the console as text. The R console is an example of a CLI. A GUI is the primary means of interacting with desktop environments, such as Windows and Mac OS X, and statistical software, such as JMP. GUIs are contained within windows, and resources, such as documents, are represented by graphical icons. User controls are packed into hierarchical drop-down menus, buttons, sliders, etc. The user manipulates the windows, icons, and menus with a pointer device, such as a mouse. The R language, like its predecessor S, is designed for interactive use through a command line interface (CLI), and the CLI remains the primary interface to R. However, the graphical user interface (GUI) has emerged as an effective alternative, depending on the specific task and the target audience. With respect to GUIs, we see R users falling into three main target audiences: those who are familiar with programming R, those who are still learning how to program, and those who have no interest in programming. On some platforms, such as Windows and Mac OS X, R has graphical front-ends that provide a CLI through a text console control. Similar examples include the multi-platform RStudioTM IDE, the Java-based JGR and the RKWard GUI for the Linux KDE desktop. Although these interfaces are GUIs, they are still very much in essence CLIs, in that the primary mode of interacting with R is the same. Thus, these GUIs appeal mostly to those who are comfortable with R programming"-- Provided by publisher.
  • Jesse Liberty and Alex Horovitz.
  • Tim Patrick.
  • v. 1-, 1963- ScienceDirect
  • 2016 Springer
    Shuren Zhang, editor.
    Antibody therapies in cancer / Shengdian Wang and Mingming Jia -- Biological response modifier in cancer immunotherapy / Ronghua Liu, Feifei Luo, Xiaoming Liu, Luman Wang, Jiao Yang, Yuting Deng, Enyu Huang, Jiawen Qian, Zhou Lu, Xuechao Jiang, Dan Zhang, and Yiwei Chu -- Therapeutic cancer vaccines / Zhenlong Ye, Zhong Li, Huajun Jin, and Qijun Qian -- Adoptive Cellular Therapy (ACT) for cancer treatment / Fan Yang, Hao Jin, Jian Wang, Qian Sun, Cihui Yan, Feng Wei, and Xiubao Ren -- Oncolytic immunotherapy for treatment of cancer / A. Tsun, X.N. Miao, C.M. Wang, and D.C. Yu.
    Also available: Print – 2016
  • 2005 Springer
    John Beynon, Nicholas D. Carr, editors.
  • v. 1-5, 1965-69.
    Status: Not Checked OutLane Catalog Record
  • v. 62-, 2005- Springer
  • 2014 Springer
    Jaroslava Halper, editor.
    This volume is a reference handbook focusing on diseases like Marfan syndrome, Ehlers-Danlos syndrome, Loeys-Dietz syndrome and other heritable soft connective tissue diseases. The book presents detailed information for both basic scientists and for clinicians seeing patients. It is also a stepping stone for new investigations and studies that goes beyond the facts about the composition and biochemistry of the connective tissue and extracellular matrix, as the authors connect individual components to specific aspects of various soft tissue disorders and to the actual or potential treatment of them. Progress in Heritable Soft Connective Tissue Diseases features very prominent physicians and scientists as contributors who bring their most recent discoveries to the benefit of readers. Their expertise will help clinicians with proper diagnosis of sometimes elusive and uncommon heritable diseases of soft connective tissues. This book also offers an update on the pathophysiology of these diseases, including an emphasis on unifying aspects such as connections between embryonic development of the different types of connective tissues and systems, and the role of TGF-beta in development and physiology of soft tissues. This new set of data explains, at least in part, why many of these disorders are interconnected, though the primary pathophysiological events, such as gene mutations, may be different for each disorder.
    Also available: Print – 2014
  • 1984-
    editors, Claude Griscelli, Jaak Vossen.
    Status: Not Checked OutLane Catalog Record
  • 2002 Karger
    volume editors, O. Hockwin, M. Kojima, N. Takahashi, D.H. Sliney.
    IX Professor Kazuyuki Sasaki, MD: clinician, scientist, leader in cataract research and friend -- 1 Lens and cataract research of the 20th century: a review of results, errors and misunderstandings -- 12 Rick factors for nuclear lens opacification: the Reykjavik eye study -- 21 A review of the epidemiologic evidence linking ultraviolet radiation and cataracts -- 32 Studies on ultraviolet radiation and health effects: ocular exposure to ultraviolet radiation -- 40 Geometrical gradients in the distribution of temperature and absorbed ultraviolet radiation in ocular tissues -- 60 High prevalence of nuclear cataract in the population of tropical and subtropical areas -- 70 Toxicity of ultraviolet radiation exposure to the lens expressed by maximum tolerable dose -- 76 Assessment of ocular exposure to visible light for population studies -- 93 The effects of protective eyewear on glare and crystalline lens transparency -- 104 Evaluation of blue-light hazards form various light sources -- 113 Experimental evidence for interactive effects of chronic UV irradiation and nutritional deficiencies in the lens -- 125 Environmental temperature and cataract progression in experimental rat cataract models -- 135 Morphological differences between lens fibers in albino and pigmented rats -- 143 Heterogeneity of ascorbate free radical reductase in the human lens -- 150 The effect of modification of [alpha]-crystallin by prednisolone -21-hemisuccinate and fructose 6-phosphate on chaperone activity -- 161 Steroid-induced cataract: other than in the who animal system, in the lens culture system, androgens, estrogens and progestins as well as glucocorticoids produce a loss o transparency of the lens -- 169 Water diffusion in the rabbit lens in vivo -- 176 Author index -- 177 Subject index.
    Also available: Print – 2002
  • 2014 Springer
    Mindy F. Levin, editor.
    "This volume is the most recent installment of the Progress in Motor Control series. It contains contributions based on presentations by invited speakers at the Progress in Motor Control IX meeting held in at McGill University, Montreal, in July, 2013. Progress in Motor Control is the official scientific meeting of the International Society of Motor Control (ISMC). The Progress in Motor Control IXI meeting, and consequently this volume, provide a broad perspective on the latest research on motor control in humans and other species"--Publisher's description.
    Also available: Print – 2014
  • 2009 Springer
    Dagmar Sternad, editor.
    Also available: Print – 2009
  • 2013 Springer
    Michael J. Richardson, Michael A. Riley, Kevin Shockley, editors.
    Model-based and model-free mechanisms of human motor learning / Adrian M. Haith, John W. Krakauer -- The molecular basis of experience-dependent motor system development / Robert G. Kalb, Weiguo Zhou, Lei Zhang -- Neurocognitive mechanisms of error-based motor learning / Rachael D. Seidler ... [et al.] -- Plasticity in the motor network following primary motor cortex lesion / Numa Dancause -- The mirror system in monkeys and humans and its possible motor-based functions / Leonardo Fogassi, Luciano Simone -- A molecular basis for intrinsic muscle properties : implications for motor control / Kiisa C. Nishikawa ... [et al.] -- Theoretical and methodological issues in serial correlation analysis / Didier Delignières, Vivien Marmelat -- On the control of unstable objects : the dynamics of human stick balancing / Ramesh Balasubramaniam -- Intermittent motor control : the "drift-and-act" hypothesis / John G. Milton.
    Also available: Print – 2013
  • 2011 Springer
    Heinz Mehlhorn, editor.
    50 years German Society of Parasitology (DGP) (1961-2010) / Johannes Eckert -- Parasitology of the German Democratic Republic (1961-1990) : memories of a time witness / Theodor Hiepe -- Parasites and their world records in their fight for survival / Heinz Mehlhorn -- Cryptosporidium parvum : the veterinary perspective / Arwid Daugschies -- Neonatal porcine coccidiosis / Hanna Lucia Worliczek and Anja Joachim -- Post-translational modifications in apicomplexan parasites / Esther Jortzik, Sebastian Kehr, and Katja Becker -- Development of the RTS, S/AS vaccine candidate from concept to phase III / Joe Cohen ... [et al.] -- Small ruminant theileriosis / Jabbar Ahmed ... [et al.] -- Interactions of Trypanosoma cruzi and triatomines / Günter A. Schaub, Christian K. Meiser, and Carsten Balczun -- Sex in schistosomes -- signaling mechanisms in the female gonads / Svenja Beckmann ... [et al.] -- Anisakid nematode (Ascaridoidea) life cycles and distribution : increasing zoonotic potential in the time of climate change? / Sven Klimpel and Harry W. Palm -- Fish parasites as biological indicators in a changing world : can we monitor environmental impact and climate change? / Harry W. Palm -- Infectious diseases under the influence of changing environmental factors / Franz J. Conraths and Thomas C. Mettenleiter -- Arthropod vectors and their growing importance in Europe / Helge Kampen and Doreen Werner -- A look at the world of ticks / Trevor N. Petney ... [et al.] -- What else besides TBE and borreliosis? : tick-transmitted pathogens in Germany and beyond / Silvia Pluta ... [et al.] -- Tick-borne encephalitis : from microfocus to human disease / G. Dobler ... [et al.].
  • v. 3-27, 1969-94. Karger
    Also available: Print – v. 8, 1975.
  • v. 28-, 1997- Karger
    Also available: Print – v. 35, 2006.
  • 2012 Springer
    Yoshibumi Nakane.
    pt. 1. Social Psychiatry and Psychiatric Epidemiology -- Definition and Historical Review of Social Psychiatry and Psychiatric Epidemiology -- The Foundation of Psychiatric Epidemiology Research -- Introduction -- pt. 2. Findings on Social Psychiatry and Psychiatric Epidemiology in Japan -- Activities of the Department of Neuropsychiatry Nagasaki University School of Medicine, as a World Health Organization Collaborating Center -- Studies on Schizophrenia -- Studies on Affective Disorders -- Studies on Patient with Affective Disorders in General Practice -- Development from Atomic Bomb Diseases to Survivors' Mental Health Support: Findings on Disaster Psychiatry.
  • 1960-
    edited by Arthur Rook.
    Status: Not Checked OutLane Catalog Record
  • v. 1-3, 1954-57.
    Hammond, John.
    Status: Not Checked OutLane Catalog Record
  • v 1-2, 1973-75.
    Zbinden, Gerhard.
    Status: Not Checked OutLane Catalog Record
  • v. 41-, 2014- Karger
  • 2012 WHO
    [World Health Organization and United Nations Children's Fund Joint Monitoring Programme for Water Supply and Sanitation Monitoring Programme].
    The WHO/UNICEF Joint Monitoring Programme for Water Supply and Sanitation (JMP) reports every two years on progress towards the drinking-water and sanitation target under Millennium Development Goal 7. This target calls for halving the proportion of the population without sustainable access to safe drinking water and basic sanitation between 1990 and 2015. Estimates presented in its 2012 update report describe the situation at the end 2010 and supersede those of the JMP update published in March 2010. The report brings welcome news: measured by the proxy-indicator consistently used by the JMP since 2000, the MDG drinking-water target was met in 2010, five years ahead of schedule. However, the job is far from done. An estimated 780 million still lacked safe drinking water in 2010, and the world is unlikely to meet the MDG sanitation target. A reduction in urban-rural disparities and inequities associated with poverty; drinking-water coverage in countries in sub-Saharan Africa and Oceania; putting sanitation 'on track'; and universal coverage beyond 2015 all remain high on the development and public health agenda.--Publisher description.
    Also available: Print – 2012
  • 2014 WHO
    WHO/UNICEF Joint Monitoring Programme for Water Supply and Sanitation.
    "Even though progress towards the MDG target represents important gains in access for billions of people around the world, it has been uneven. Sharp geographic, sociocultural and economic inequalities in access persist and sometimes have increased. This report presents examples of unequal progress among marginalized and vulnerable groups. Section 1 presents the status of and trends in access to improved drinking water sources and sanitation. Section 2 provides a snapshot of inequalities in access to improved drinking water sources and sanitation. Section 3 presents efforts to strengthen monitoring of access to safe drinking water and sanitation services under a post-2015 development agenda, as well as the challenges associated with these efforts."--Publisher's website.
    Also available: Print – 2014
  • 2010 WHO
    Also available: Print – 2010
  • 2015 WHO
    Despite significant progress in water and sanitation, much still remains to be done. This report shows how the world has changed since 1990. It provides an assessment of progress towards the MDG target, and insight into the remaining challenges. Section A provides an overview of progress against the parameters specified in the MDG target for water and sanitation, in both urban and rural areas. It presents data for the world as a whole, and compares progress across regions. The report goes on to examine trends over the MDG period by region and by level of service. It pays particular attention to the numbers of people who have gained the highest level of service in drinking water supply -- piped water on premises -- and those with no service at all, who use surface water for drinking and practise open defecation.
    Also available: Print – 2015
  • 2015
    Ministry of Health Malaysia and the World Health Organization and the University of California, San Francisco.
    This case study examines the strategies and policies of the Malaysian National Malaria Control Programme (NMCP) and outlines the dramatic decline in malaria cases nationally since 1991. It documents the history of malaria in the country and malaria control interventions that have been successfully implemented. The case study also highlights current strategies to reach the country's national target of eliminating malaria by 2020. Lessons for countries that are embarking upon elimination are distilled.
  • 2013 Springer
    Alastair Wilkins, editor.
    Progressive multiple sclerosis places a huge burden on individuals, carers and society and treatment options are currently limited. However, there have been significant recent advances in understanding progressive disease and this book draws the field together into a single, accessible, clinically focused text. Progressive Multiple Sclerosis sets out the basic science, pathology, epidemiology and treatment possibilities in progressive multiple sclerosis. The biological processes underlying disease progression are elucidated as are specific pathophysiological mechanisms. The basic science of axonal degeneration and the clinical understanding of progressive multiple sclerosis are discussed in the context of emerging and future therapies for disease progression as are trials which might be conducted for progressive multiple sclerosis. An overview of biomarkers for the disease is included and existing symptomatic therapies for progressive multiple sclerosis are covered in detail. Each chapter addresses specific aspects of progressive multiple sclerosis providing an extensive review of the current literature and a discussion of the likely mechanisms of tissue injury relevant to the disease. Progressive Multiple Sclerosis is ideal for both general neurologists and those with a specialist interest in multiple sclerosis. It will also be of interest to neurologists in training and other medical professionals treating this common disease. Dr Alastair Wilkins is Senior Lecturer in Neurology, University of Bristol, and Consultant Neurologist at Frenchay Hospital, Bristol, UK. He researches axonal injury in multiple sclerosis and related disorders.
  • 2015 Karger
    volume editors, Holger Christiansen, Nina Merete Christiansen.
    Clinical features of progressive neuroblastoma / Simon, T. -- DNA copy number changes and beyond / Fieuw, A.; Schulte, J.; De Preter, K.; Speleman, F. -- Genomic alterations and abnormal cell cycle in high-risk neuroblastoma / Capasso, M.; Sidarovich, V.; Quattrone, A.; Tonini, G.P. -- MYCN and microRNAs / Althoff, K.; Schulte, J.H. -- MYCN and its posttranslational regulation in neuroblastoma / Otto, T. -- Neuroblastoma and the P53 pathway / Chen, L.; Tweddle, D.A. -- Targeting cell death pathways in neuroblastoma / Fulda, S. -- Neuroblastoma and angiogenesis / Russler, J. -- The role of the anaplastic lymphoma kinase receptor in neuroblastoma / Yeung, C.M.; George, R.E. -- Molecular-targeted therapy in refractory or relapsed neuroblastoma / Corbacioglu, S. -- Immune regulation in neuroblastoma / Fest, S.; Starke, S. -- Approaches to passive and active vaccination against neuroblastoma / Lode, H.N. -- Role of cell therapy in neuroblastoma / Bremm, M.; Brehm, C.; Huenecke, S.; Rettinger, E.; Bader, P. -- Minimal residual disease in neuroblastoma / Weber, A.
  • 2011 CRCnetBASE
    David Shirley.
    "A growing number of healthcare organizations are implementing project management principles to improve cost and service efficiencies. They are in desperate need of resources that clearly illustrate the project management needs of todays healthcare professional. Project Management for Healthcare fills this need. Using easy-to-follow language, it explains how the time-tested principles of project management can help maximize limited resources and ensure the highest possible quality of care. Exploring the discipline of project management from the perspective of the healthcare environment, the book dissects the project process and provides the tools and techniques required to successfully plan, execute, and control any healthcare-based project. From identifying stakeholders to constructing a project plan, this book covers the complete spectrum of project planning activities. Complete with chapter summaries, exercises, hints, review questions, and case studies, it illustrates applications across a range of healthcare settings. Explains how to utilize the project plan to execute projects within budget, schedule, and quality objectives Covers program management as it relates to healthcare Addresses the interaction between healthcare and information technology Presents best practices from the pharmaceutical and medical equipment industries that can easily be adapted to any helthcare setting Because most healthcare personnel will inevitably have to work with program management and need to interact with pharmaceutical companies and medical device manufacturers, the book provides an inside look at the processes and best practices used to bring products to market in these industries. Explaining how to adapt these processes to drive down costs and improve the quality of care in any healthcare setting, the book includes a case study of a fictitious medical facility that illustrates the proper application of the tools and techniques needed to manage healthcare projects effectively and efficiently"--Provided by publisher.
  • 2007 Springer
    Susan M. Houston, Lisa Anne Bove.
  • v. 1, 1952.
    by Claire Myers Vernier, Ph.D. .... ; foreword by Isabelle V. Kendig, Ph.D. ...
    Status: Not Checked OutLane Catalog Record
    1. Projective drawings.
  • 2013 Springer
    Eugene Rosenberg (editor-in-chief) ; Edward F. DeLong, Stephen Lory, Erko Stackebrandt and Fabiano Thompson (eds.).
    The gut microbiota -- Prebiotics -- Probiotics -- Identification of pathogens by classical clinical tests -- Identification of pathogens by nonculturing molecular techniques -- Bacterial adhesion -- Cholera -- Tuberculosis -- Legionnaires' disease -- Listeria -- Diphtheria -- Botulism and tetanus -- Whooping cough -- Dysentery -- Urinary tract infections -- Burn infections -- Typhoid -- Meningitis -- Rickettsiia diseases -- Syphilis -- Chlamydial diseases -- Bacterial toxins.
  • 2013 Springer
    Eugene Rosenberg (editor-in-chief), Edward F. DeLong...[et al.] (eds.).
    Organic Acid and Solvent Production: Acetic, Lactic, Gluconic, Succinic, and Polyhydroxyalkanoic Acids / Palmer Rogers, Jiann-Shin Chen, Mary Jo Zidwick -- Organic Acid and Solvent Production: Butanol, Acetone, and Isopropanol; 1,3- and 1,2-Propanediol Production; and 2,3-Butanediol Production / Jiann-Shin Chen, Mary Jo Zidwick, Palmer Rogers -- Organic Acid and Solvent Production: Propionic and Butyric Acids and Ethanol / Mary Jo Zidwick, Jiann-Shin Chen, Palmer Rogers -- Amino Acid Production / Hidehiko Kumagai -- Microbial Exopolysaccharides / Avinash Mishra, Dr. Bhavanath Jha -- Bacterial Enzymes / Prof. Wim J. Quax -- Diversity and Biotechnological Applications of Prokaryotic Enzymes / Alane Beatriz Vermelho, Eliane Ferreira Noronha, Edivaldo Ximenes Ferreira Filho -- Bacteria in Food and Beverage Production / Dr. Michael P. Doyle, Larry R. Steenson, Jianghong Meng -- Bacterial Pharmaceutical Products / Giancarlo Lancini, Dr. Arnold L. Demain -- Biosurfactants / Dr. Eugene Rosenberg, Eliora Z. Ron -- Bioremediation / Ronald L. Crawford, Dr. Eugene Rosenberg -- Biodeterioration / Ji-Dong Gu, Ralph Mitchell -- Microbial Biofilms / Dirk De Beer, Paul Stoodley -- Biofuels / Stefano Freguia, Bernardino Virdis, Dr. Korneel Rabaey -- The Metabolic Pathways of Biodegradation / Lawrence P. Wackett.
  • 2013 Springer
    Eugene Rosenberg (editor-in-chief) ; Edward F. DeLong, Stephen Lory, Erko Stackebrandt and Fabiano Thompson (eds.).
    Section 1: Biology of Bacteria and Archaea. How We Do, Don't, and Should Look at Bacteria and Bacteriology / Carl R. Woese -- What Is a Prokaryote? / W. Ford Doolittle, Olga Zhaxybayeva -- Prokaryotes and Their Habitats / Hans G. Schlegel, Holger W. Jannasch -- Origin of Life: RNA World Versus Autocatalytic Anabolist / Günter Wächtershäuser -- Morphological and Physiological Diversity / Stephen H. Zinder, Martin Dworkin -- Prokaryote Characterization and Identification / Peter Kämpfer, Stefanie P. Glaeser -- Principles of Enrichment, Isolation, Cultivation, and Preservation of Prokaryotes / Jörg Overmann -- Comparative Genomics / Asli Ismihan Ozen, Tammi Vesth, David W. Ussery -- Defining Taxonomic Ranks / Konstantinos T. Konstantinidis, Erko Stackebrandt -- Population Genetics / Santiago Castillo-Ramírez, Edward J. Feil -- Public Service Collections and Biological Resource Centers of Microorganisms / David Smith, Dagmar Fritze, Erko Stackebrandt -- Repositories for Patented and Safeguarded Material / Zea D. V. L. Mayerhoff, Irene von der Weid, Alessandra B. G. Valladão -- Biotechnology and Applied Microbiology / Eugene Rosenberg -- Genomes and Post-genome Technology / Betania Ferraz Quirino, Cristine Chaves Barreto, Georgios J. Pappas Jr. -- Section 2: Symbiotic Associations. Role of Microorganisms in Adaptation, Development, and Evolution of Animals and Plants: The Hologenome Concept / Eugene Rosenberg, Ilana Zilber-Rosenberg -- Cyanobacterial-Plant Symbioses / David G. Adams, Birgitta Bergman, Sandra A. Nierzwicki-Bauer, Paula S. Duggan -- Root and Stem Nodule Bacteria of Legumes / Michael J. Sadowsky, Peter H. Graham, Masayuki Sugawara -- Symbiotic Associations Between Ciliates and Prokaryotes / Michael Schweikert, Masahiro Fujishima, Hans-Dieter Görtz -- Bacteriocyte-Associated Endosymbionts of Insects / Paul Baumann, Nancy A. Moran, Linda C. Baumann -- Vibrio fisheri: Squid Symbiosis / Eric V. Stabb, Karen L. Visick -- Rumen Symbioses / Itzhak Mizrahi -- Symbiotic Associations Between Termites and Prokaryotes / Andreas Brune -- Marine Chemosynthetic Symbioses / Colleen M. Cavanaugh, Zoe P. McKiness, Irene L. G. Newton, Frank J. Stewart.
  • 2013 Springer
    Eugene Rosenberg, editor-in-chief ; Edward F. DeLong, Stephen Lory, Erko Stackebrandt, Fabiano Thompson.
    Section 1: Prokaryotic Communities. Structure and Function of Microbial Communities / David A. Stahl, Jason J. Flowers, Meredith Hullar, Seana Davidson -- Quantitative and Theoretical Microbial Population Biology / Martin F. Polz, William P. Hanage -- Alpine and Arctic Soil Microbial Communities / M. Rhodes, J. Knelman, R. C. Lynch, J. L. Darcy, D. R. Nemergut, S. K. Schmidt -- Plant Rhizosphere Microbial Communities / Dror Minz, Maya Ofek, Yitzhak Hadar -- Tropical Soil Microbial Communities / Andrew Macrae, Rosalie R. R. Coelho, Raquel Peixoto, Alexandre S. Rosado -- Freshwater Microbial Communities / Jakob Pernthaler -- Pelagic Oxygen Minimum Zone Microbial Communities / Osvaldo Ulloa, Jody J. Wright, Lucy Belmar, Steven J. Hallam -- Marine Deep Sediment Microbial Communities / Andreas Teske -- Sea-Ice Microbial Communities / John P. Bowman -- Coral Reef Bacterial Communities / David G. Bourne, Nicole S. Webster -- Section 2: Ecophysiology -- Planktonic Versus Sessile Life of Prokaryotes / Kevin C. Marshall -- The Phototrophic Way of Life / Jörg Overmann, Ferran Garcia-Pichel -- The Anaerobic Way of Life / Ruth A. Schmitz, Rolf Daniel, Uwe Deppenmeier, Gerhard Gottschalk -- The Chemolithotrophic Prokaryotes / Donovan P. Kelly, Ann P. Wood -- Bacterial Behavior / Judith P. Armitage, Kathryn A. Scott -- Prokaryotic Life Cycles / Lawrence J. Shimkets -- Life at High Temperatures / Rainer Jaenicke, Reinhard Sterner -- Life at Low Temperatures / Thilo M. Fuchs, Klaus Neuhaus, Siegfried Scherer -- Life at High Salt Concentrations / Aharon Oren -- Alkaliphilic Prokaryotes / Terry Ann Krulwich, Masahiro Ito -- Syntrophism Among Prokaryotes / Bernhard Schink, Alfons J. M. Stams -- Quorum Sensing / Bonnie L. Bassler, Melissa B. Miller -- Cell-Cell Interactions / Dale Kaiser.
  • 2013 Springer
    edited by Edward D. DeLong, Eugene Rosenberg, Stephen Lory, Erko Stackebrandt, Fabiano Thompson.
    Physiology and Biochemistry -- Acetogenic Prokaryotes / Harold L. Drake, Kirsten Küsel, Carola Matthies -- Virulence Strategies of Plant Pathogenic Bacteria / Maeli Melotto, Barbara N. Kunkel -- Oxidation of Inorganic Nitrogen Compounds as an Energy Source / Eberhard Bock, Michael Wagner -- H₂-Metabolizing Prokaryotes / Edward Schwartz, Johannes Fritsch, Bärbel Friedrich -- Hydrocarbon-Oxidizing Bacteria / Eugene Rosenberg -- Lignocellulose-Decomposing Bacteria and Their Enzyme Systems / Edward A. Bayer, Yuval Shoham, Raphael Lamed -- Aerobic Methylotrophic Prokaryotes / Ludmila Chistoserdova, Mary E. Lidstrom -- Dissimilatory Fe(III)- and Mn(IV)-Reducing Prokaryotes / Derek Lovley -- Dissimilatory Sulfate- and Sulfur-Reducing Prokaryotes / Ralf Rabus, Theo A. Hansen, Friedrich Widdel -- Denitrifying Prokaryotes / James P. Shapleigh -- Dinitrogen-Fixing Prokaryotes / Ernesto Ormeño-Orrillo, Mariangela Hungria, Esperanza Martinez-Romero -- Magnetotactic Bacteria / Dennis A. Bazylinski, Christopher T. Lefèvre, Dirk Schüler -- Luminous Bacteria / Paul V. Dunlap, Henryk Urbanczyk -- Halophilic and Haloalkaliphilic Sulfur-Oxidizing Bacteria / Dimitry Y. Sorokin, Horia Banciu, Lesley A. Robertson, J. Gijs Kuenen -- Colorless Sulfur Bacteria / Gerard Muyzer, J. Gijs Kuenen, Lesley A. Robertson -- Bacterial Stress Response / Eliora Z. Ron -- Anaerobic Biodegradation of Hydrocarbons Including Methane / Johann Heider, Karola Schühle -- Physiology and Biochemistry of the Methane-Producing Archaea / Reiner Hedderich, William B. Whitman.
  • 2010 Springer
    edited by: A. Graham Pockley, Stuart K. Calderwood and M. Gabriella Santoro.
  • 2010 Springer
    Helmut König, Harald Claus, Ajit Varma, editors.
    Part I. Cell Wall Polymers and Structures of Bacteria -- 1. The Murein Sacculus / Silke Litzinger and Christoph Mayer -- 2. Occurrence, Structure, Chemistry, Genetics, Morphogenesis, and Functions of S-Layers / Paul Messner, Christina Schäffer, Eva-Maria Egelseer, and Uwe B. Sleytr -- 3. Bacterial Polysaccharide Capsules / David Corbett, Thomas Hudson, and Ian S. Roberts -- 4. Lipopolysaccharides / Alba Silipo, Cristina De Castro, Rosa Lanzetta, Michelangelo Parrilli, and Antonio Molinaro -- 5. Structure, Biosynthesis, and Function of Teichoic Acids and Related Cell Wall Glycopolymers in the Gram-positive Cell Envelope / Maren Rautenberg, Thomas Kohler, Guoqing Xia, Emir Kulauzovic, and Andreas Peschel -- 6. Outer Membrane Proteins / Oliver Mirus, Alexander Hahn, and Enrico Schleiff -- Part II. Cell Wall Polymers and Structures of Archaea -- 7. Cell Envelopes of Methanogens / Harald Claus and Helmut König -- 8. The Cell Envelopes of Haloarchaea: Staying in Shape in a World of Salt / Jerry Eichler, Mehtap Abu-Qarn, Zvia Konrad, Hilla Magidovich, Noa Plavner, and Sophie Yurist-Doutsch -- 9. Cell Envelopes of Crenarchaeota and Nanoarchaeota / Reinhard Rachel -- Part III. Biological Activities -- 10. Immunochemistry of the Cell Walls of Methanogenic Archaea: A View from the Past into the Future / Everly Conway de Macario and Alberto J.L. Macario -- 11. Cell Wall Structure and Pathogenicity / T.A. Oelschlaeger, U. Dobrindt, and J. Hacker -- Part IV. Cell Wall Growth and Inhibition -- 12. Cell Wall Targeted Antibiotics / Regine Hakenbeck, Reinhold Brückner, and Bernhard Henrich -- 13. Bacterial Autolysins / Marie-Pierre Chapot-Chartier -- Part V. Cell Wall Interactions -- 14. Prokaryotic Cell-Cell Interaction / Reinhard Wirth -- 15. Adhesion of Bacteria to Protists / Renate Radek -- Part VI. Application of Cell Wall Components -- 16. Prokaryotic Cell Wall Components: Structure and Biochemistry / Uwe B. Sleytr, Eva-Maria Egelseer, Nicola Ilk, Paul Messner, Christina Schäffer, Dietmar Pum, and Bernhard Schuster -- 17. Accumulation of Heavy Metals by Micro-organisms: Biomineralization and Nanocluster Formation / Sonja Selenska-Pobell and Mohamed Merroun.
  • 2015 Springer Protocols
    Nevan J. Krogan, Mohan Babu, editors.
    This book focuses on innovative experimental and computational approaches for charting interaction networks in bacterial species. The first part of the book consists of nine chapters, focusing on biochemical and genetics and genomics approaches including yeast two hybrid, metagenomics, affinity purification in combination with mass spectrometry, chromatin-immunoprecipitation coupled with sequencing, large-scale synthetic genetic screens, and quantitative-based mass spectrometry strategies for mapping the bacterial physical, functional, substrate, and regulatory interaction networks needed for interpreting biological networks, inferring gene function, enzyme discovery, and identifying new drug targets. The second part comprises five chapters, covering the network of participants for protein folding and complex enzyme maturation. It also covers the structural approaches required to understand bacterial intramembrane proteolysis and the structure and function of bacterial proteins involved in surface polysaccharides, outer membrane, and envelope assembly. This volume concludes with a focus on computational and comparative genomics approaches, especially network-based methods for predicting physical or functional interactions, and integrative analytical approaches for generating more reliable information on bacterial gene function. This book provides foundational knowledge in the understanding of prokaryotic systems biology by illuminating how bacterial genes f unction within the framework of global cellular processes. The book will enable the microbiology community to create substantive resources for addressing many pending unanswered questions, and facilitate the development of new technologies that can be applied to other bacterial species lacking experimental data.
    Also available: Print – 2015
  • 2013 Springer
    Kenn Gerdes, editor.
    Introduction -- Type I Toxin - Antitoxin Systems: Hok/Sok and Fst -- Novel Type I Toxin - Antitoxin Systems -- Type II TA Loci: The Ccdab and Parde Families -- Type II TA Loci: The Relbe Family -- Type II TA Loci: The Unusual Mqsra Locus -- Type II TA Loci: The Mazef Family -- Type II TA Loci: Vapbc and Other TA Loci In Mycobacteria -- Type II TA Loci: Phd Doc Family -- Type II TA Loci: The Fic Family -- Type II TA Loci, Hipab And Persisters -- Type II TA Loci: Zeta/Pezt Family -- Type II Loci: Phylogeny -- Type III TA Loci -- TA Loci Encoded By Plasmids -- TA Loci in Archaea -- TA Loci in Mycobacterium Tuberculosis -- TA Loci in Streptococcus Pneumoniae -- Biotechnological and Medical Exploitations Of TA Genes and Their Components.
  • 2013 Springer
    Denis Corbeil, editor.
    Also available: Print – 2013
  • 2005 Springer
    J. Morser, S.I. Nishikawa, editors.
    Melanocyte system for studying stem cell niche -- Establishment and maniupulation of monkey and human embryonic stem cell lines for biomedical research -- Human embryonic stem cell derivation -- In search of the elusive epidermal stem cell -- Corneal cells for regeneration -- Polycomb gene product Bmi-l -- Directed differentiation of neural and sensory tissues from embryonic stem cells in vitro -- Stem cell biology for vascular regeneration.
  • 2013 WIPO
    World Health Organization, WIPO, World Intellectual Property Organization, World Trade Organization.
    Also available: Print – 2013
  • 2008 Springer
    Athena Linos, Wilhelm Kirch, editors ; foreword by Karen Messing.
    Pt. 1. General principles and concepts. Introduction to health promotion for working women: a methodology / Pania Karnaki ... [et al.] -- The legal context for workplace safety and health promotion: thinking of women / Ioannis Polychronakis ... [et al.] -- Pt. 2. Specific health topics. Workplace health promotion interventions concerning women workers' occupational hazards / Ioannis Polychronakis ... [et al.] -- Mental health disorders and work-life balance / Natalie M. Schmitt, Andreas Fuchs and Wilhelm Kirch -- Musculoskeletal disorders / Verka Koytcheva ... [et al.] -- Work-related violence, bullying, and sexual harassment / Kaisa Kauppinen and Tarita Tuomola -- Promoting health for working women: communicable diseases / Sotirios Tsiodras -- Screening at the workplace and female employees / Elena Riza and Athena Linos -- Pt. 3. Women's reproductive health issues. Workplace health promotion aiming at safe working environments for pregnant women / Alex Burdorf and Goedele Geuskens -- Workplace health promotion aimed at increasing breastfeeding / Goedele Geuskens and Alex Burdorf -- Pt. 4. Lifestyle determinants. Promoting tobacco awareness and smoking cessation for working women / Sherry Merkur -- Women, health, and alcohol-related harm / Kaisa Kauppinen and Tarita Tuomola -- Promoting physical activity and a healthy diet among working women / Gemma Janer and Manolis Kogevinas.
  • 2007
    World Health Organization.
    Status: Not Checked OutLane Catalog Record
  • 2007 Springer
    edited by Harald Klingemann, Linda Carter Sobell.
    The phenomenon of self-change: overview and key issues -- Self-change from alcohol and drug abuse: often-cited classics -- Natural recovery or recovery without treatment from alcohol and drug problems as seen from survey data -- Remission without formal help: new directions in studies using survey data -- Natural recovery from alcohol and drug problems: a methodological review of the literature from 1999 through 2005 -- Self-change in a broader context: beyond alcohol and drugs -- One way to leave your lover: the role of treatment in changing addictive behaviors -- Promoting self-change: taking the treatment to the community -- Hostile and favorable societal climates for self-change: some lessons for policymakers -- Natural recovery: a cross-cultural perspective -- Self-change toolbox: tools, tips, websites, and other informational resources for assessing and promoting self-change.
  • 2012 Karger
    volume editor, Herbert Pfister.
    Virology and pathogenesis / Pfister, H. -- Epidemiology of mucosotropic papillomaviruses / Gissmann, L. -- Condylomata acuminata / Gross, G. -- Recurrent respiratory papillomatosis / Wittekindt, C.; Wagner, S.; Klussmann, J.P. -- Cervical cancer and intraepithelial neoplasia / Schneider, A. ... [et al.] -- Cancer and intraepithelial neoplasia of the vulva and vagina / Petry, K.U. -- Penile cancer and penile intraepithelial neoplasia / Gross, G. -- Anal cancer and intraepithelial neoplasia / Wieland, U. ; Kreuter, A. -- Tonsillar cancer / Klussmann, J.P.; Wagner, S.; Wittekindt, C. -- Cytology / Ikenberg, H. -- Concepts of biomarker development / von Knebel Doeberitz, M.; Vinokurova, S.; Reuschenbach, M. -- Detection of human papillomavirus DNA and RNA / Ikenberg, H. -- Human papillomavirus testing in primary screening for cervical cancer / Petry, K.U. -- Primary prevention by vaccination / Kaufmann, A.M.; Gissmann, L.
  • Soraya M. Coley, Cynthia A. Scheinberg.
    An orientation to proposal writing -- Definitions -- Types of grant applications -- Components of a proposal -- The process of submitting a proposal -- The difference between grants and contracts -- Organizing the writing -- Writing for an established organization or a new organization -- Writing style and format -- Using technology in proposal development -- The role and use of search engines -- Review of funder's web sites -- Evaluating data and other information -- Electronic submission of the proposal -- Understanding the agency, the community, and the funder -- Understanding the agency -- Understanding the community -- Understanding the funder -- Problem- or needs-based program development -- Understanding the community through data -- Understanding barriers to service -- Program design and theoretical orientations -- Conceptualizing program ideas -- Working with a collaborative -- Sustainability and institutionalization -- Writing the needs or problem statement -- Definitions -- The purpose of the needs/problem statement -- A guide to writing the needs/problem statement -- Writing goals, objectives, and the implementation plan -- Secion one : goals and objectives -- Section two : implementation plan -- Writing the evaluation plan -- The benefits of evaluation -- Developing an evaluation plan -- Writing the evaluation section -- Other evaluation considerations -- Creating the budget -- Types of budgets -- Budgeting for the first-time grant writer -- Other budgeting issues -- Agency capability and finishing touches -- The agency capability statement -- Requesting letters of support -- The proposal abstract -- The title and title page -- The cover letter -- Frequently asked questions (FAQs) -- Appendix A: Estimating time -- Appendix B: Funding resource information -- References and suggested readings -- Index -- About the authors.
  • 2011 Springer Protocols
    edited by Majambu Mbikay, Nabil G. Seidah.
    On the Discovery of Precursor Processing -- The Prohormone Theory and the Proprotein Convertases: It Is All About Serendipity -- The Proprotein Convertases, 20 Years Later -- Insights from Bacterial Subtilases into the Mechanisms of Intramolecular Chaperone-Mediated Activation of Furin -- The Novel Role of Cathepsin L for Neuropeptide Production Illustrated by Research Strategies in Chemical Biology with Protease Gene Knockout and Expression -- In Vitro Assay for Protease Activity of Proprotein Convertase Subtilisin Kexins (PCSKs): An Overall Review of Existing and New Methodologies -- Inhibitor Screening of Proprotein Convertases Using Positional Scanning Libraries -- Analyses of PCSK9 Post-Translational Modifications Using Time-of-Flight Mass Spectrometry -- The Molecular Biology of Furin-Like Proprotein Convertases in Vascular Remodelling -- Identification of the Myosin Heavy Polypeptide 9 as a Downstream Effector of the Proprotein Convertases in the Human Colon Carcinoma HT-29 Cells -- Regulation of 7B2 mRNA Translation: Dissecting the Role of Its 5'-Untranslated Region -- Analysis of Epigenetic Alterations to Proprotein Convertase Genes in Disease -- Genetic and Functional Characterization of PCSK1 -- Prohormone Processing in Zebrafish -- Use of Zebrafish and Knockdown Technology to Define Proprotein Convertase Activity -- Characterization of Impaired Processing of Neuropeptides in the Brains of Endoproteases Knockout Mice -- Quantitative Peptidomics of Mice Lacking Peptide-Processing Enzymes -- A Proteomic Protocol to Identify Physiological Substrates of Proprotein Convertases -- Neurophenotyping Genetically-Modified Mice for Social Behavior.
  • 2016 Springer
    Mieczyslaw Pokorski, editor.
    Application of array comparative genomic hybridization in newborns with multiple congenital anomalies / Krzysztof Szczałuba [and 10 others] -- Cytogenomic evaluation of children with congenital anomalies: critical implications for diagnostic testing and genetic counseling / Krzysztof Szczałuba [and 7 others] -- Impairment of immune function in children with familial hemophagocytic lymphohistiocytosis / K. Popko [and 9 others] -- Thyroid function in obese children and adolescents and its association with anthropometric and metabolic parameters / Małgorzata Rumińska [and 3 others] -- Relationship between 25(OH)D and IgF-I in children and adolescents with growth hormone deficiency / E. Witkowska-Se̜dek [and 3 others] -- Viral infections in children in the 2014/2015 epidemic season in Poland / E. Hallmann-Szelińska [and 4 others] -- Gastroesophageal reflux disease in children with interstitial lung disease / M.A. Dziekiewicz [and 10 others] -- Treatment outcomes in children with Henoch-Schönlein nephritis / Małgorzata Mizerska-Wasiak [and 4 others] -- Respiratory function and language abilities of profoundly deaf adolescents with and without cochlear implants / A. Żebrowska [and 5 others] -- High-frequency jet ventilation against small-volume conventional mechanical ventilation in the rabbit models of neonatal acute lung injury / D. Mokra [and 6 others].
    Also available: Print – 2016
  • 2013 Springer
    Andrew T. Chan, Elmar Detering, editors.
    Mechanistic aspects of COX-2 expression in colorectal neoplasia -- Mode of action of aspirin as a chemopreventive agent -- Coxibs: pharmacology, toxicity and efficacy in cancer clinical trials -- COX-2 active agents in the chemoprevention of colorectal cancer -- New NSAID targets and derivatives for colorectal cancer chemoprevention -- Aspirin in prevention of sporadic colorectal cancer: current clinical evidence and overall balance of risks and benefits -- Nutritional agents with anti-inflammatory properties in chemoprevention of colorectal neoplasia -- Genetics, inheritance and strategies for prevention in populations at high risk of colorectal cancer (CRC).
  • 2013 Springer
    Abdulhameed Sabu, Anu Augustine, editors.
    The book entitled "Prospects in Bioscience: Addressing the issues" is a collection of selected research papers presented at the International Conference on Advances in Biological Sciences (ICABS) organized by the Department of Biotechnology and Microbiology and the Inter University Centre for Bioscience, Kannur University, Kerala, India. ICABS witnessed a unique spectrum of Scientific Programmes on the most recent and exciting developments in modern biology. The conference displayed the numerous breakthroughs and significant developments in the important areas of modern biology and their relevance to the welfare of global society. The Book contains 50 well written chapters, each one discussing scientifically organized findings of original research work done in reputed laboratories. Needless to say, they deal with advances in various disciplines of modern biology including Cell and Molecular Biology, Structural Biology, Industrial and Environmental Biotechnology, Food and Agricultural Biotechnology and Medical Biotechnology. As the title rightly indicates, the chapters project the prospects in the respective areas and the issues in them. Specific issues discussed in the book includes development of transgenic plants, bioremediation of toxic industrial effluents, biotransformation for novel antibiotics, biofertilizer development, molecular drug designing and structure elucidation, molecular identification of pathogens, production of anti microbials, biocontrol agents and bioactive molecules, cancer biology, plant breeding and hybrid seed production etc. The book with its contents spreading across the vast arena of modern biology is expected to cater to the need of researchers, technologists and students.
  • ScienceDirect
    edited by William E.M. Lands, William L. Smith.
    Also available: Print – 1982
  • v. 1-2, 1980.
    Upjohn.
    Status: Not Checked OutLane Catalog Record
  • 2008 Springer
    edited by J. Stephen Jones.
    Defining the problem : from subclinical disease to clinically insignificant prostate cancer / Wael Sakr -- What every patient should know about prostate cancer before he submits to biopsy of his prostate / Thomas A. Stamey, Rosalie Nolley, and Dorothea Torti -- Prostate-specific antigen and prostate cancer screening / Stacy Loeb, Misop Han, and William J. Catalona -- The role of complexed prostate-specific antigen in prostate cancer screening / Matthew E. Nielsen and Alan W. Partin -- Newly recognized forms of prostate-specific antigen and emerging molecular markers / Eduardo I. Canto and Kevin M. Slawin -- The role of prostate-specific antigen velocity in the diagnosis and management of prostate cancer / H. Ballentine Carter -- Prostate cancer screening : navigating the controversy / Timothy C. Brand and Ian M. Thompson -- Prostate cancer nomograms and how they measure up to neural networks / Pierre I. Karakiewicz and Michael W. Kattan -- Preparation for prostate biopsy / Alan M. Nieder and Mark S. Soloway -- Principles of prostate ultrasound / Martha K. Terris -- Minimizing pain and optimizing patient experience during prostate biopsy / J. Stephen Jones -- Prostate biopsy techniques / Katsuto Shinohara -- Biopsy strategies-how many and where? / Joseph C. Presti, Jr. -- Transperineal prostate biopsy / Paolo Emiliozzi and Vito Pansadoro -- Repeat prostate biopsies and the Vienna nomograms / Bob Djavan and Sibylle Marihart -- Saturation biopsy for detection and characterization of prostate cancer / J. Stephen Jones -- Pathologic implications of prostate biopsy / Ming Zhou and Cristina Magi-Galluzzi -- Complications of transrectal ultrasound-guided prostate biopsy / Sam S. Chang and Michael S. Cookson -- Management and controversies of high-grade prostatic intraepithelial neoplasia and atypical small acinar proliferation on prostate biopsy / Alon Z. Weizer ... [et al.] -- Future directions in prostate cancer diagnosis / Nicholas J. Fitzsimons ... [et al.]
  • 2012 Springer
    Rajal B. Shah, Ming Zhou, authors.
    Anatomy and Normal Histology of the Prostate Pertinent to Biopsy Practice -- Prostate Needle Biopsy Sampling Techniques: Impact on Pathological Diagnosis -- Diagnosis of Limited Cancer in Prostate Biopsy -- Immunohistochemistry in Prostate Biopsy Evaluation -- Contemporary Approach to Gleason Grading of Prostate Cancer -- Histologic Variants of Prostate Carcinoma -- Benign Mimics of Prostate Carcinoma -- Atypical Cribriform Lesions of the Prostate Gland: Emerging Concepts of Intraductal Carcinoma of the Prostate (IDC-P) -- High-Grade Prostatic Intraepithelial Neoplasia -- Atypical Glands Suspicious for Cancer -- Spindle Cell Lesions of the Prostate Gland -- Treatment Effect in Benign and Malignant Prostate Tissue -- Molecular Biology of Prostate Cancer and Emerging Diagnostic and Prognostic Biomarkers -- Biopsy Specimen Handling, Processing, Quality Assurance Program -- Reporting of Prostate Biopsy.
  • 2010 ClinicalKey
    edited by Li-Ming Su.
    Each volume in the Early Detection and Treatment of Cancer Series is packed with practical, authoritative information designed to cover the full range of diagnostic procedures, including pathologic, radiologic, bronchoscopic, and surgical aspects. You'll be able to determine the safest, shortest, least invasive way to reach an accurate diagnosis; stage the disease; and choose the best initial treatment for early stages. Based on current evidence in the literature, authors provide clinical, hands-on tools to help you make informed decisions on precisely what tests and imaging studies are needed to diagnose and stage each type of cancer. Practical, authoritative, and highly-illustrated, this volume in the brand new Early Detection and Treatment of Cancer series covers current protocols and the latest advances in diagnostic imaging and molecular and serologic markers for prostate cancer. Apply expert advice on the best "next-step" plan for different presentations and tips for less invasive protocols. Get clinical, hands-on tools to help you make informed decisions on precisely what tests and imaging studies are needed for accurate diagnosis and staging. Clear figures, tables, and boxes illustrate step-by-step care of the full range of problems encountered.
  • 2007 Springer
    J. Ramon, L.J. Denis (eds.).
    Also available: Print – 2007
  • 2013 Springer
    Donald J. Tindall, editor.
    Cell biology. Stem cells in the normal and malignant prostate / Norman J. Maitland -- Role of reactive stroma in prostate cancer / Rebeca San Martin, David R. Rowley -- The role of cholesterol in prostate cancer / Keith R. Solomon, Kristine Pelton, Michael R. Freeman -- Genetics. PTEN in prostate cancer / Marcus A. Ruscetti, Hong Wu -- ETS fusion genes in prostate cancer / J. Chad Brenner, Arul M. Chinnaiyan, Scott A. Tomlins -- Cell signaling. Signaling mechanisms of Vav3, a guanine nucleotide exchange factor and androgen receptor coactivator, in physiology and prostate cancer progression / Leah S. Lyons, Kerry L. Burnstein -- Transforming growth factor-beta in prostate cancer / David Danielpour -- The p38 MAPK pathway in prostate cancer / Daniel Djakiew -- NF-kappaB2/p52 in prostate cancer / Nagalakshmi Nadiminty, Ramakumar Tummala, Yezi Zhu -- The functional role of DAB2IP, a homeostatic factor, in prostate cancer / Eun-Jin Yun, Kaijie Wu, Yuh-Shyan Tsai -- Tyrosine kinases in prostate cancer / Yun Qiu, Dhanraj Deshmukh -- Human prostatic acid phosphatase in prostate carcinogenesis / Sakthivel Muniyan, Yu-Wei Chou, Shou-Qiang Ou-Yang -- Hormonal. Truncated androgen receptor splice variants in prostate cancer / Peter E. Lonergan, Donald J. Tindall -- Biology and clinical relevance of estrogen receptors in prostate cancer / Shuk-Mei Ho, Pheruza Tarapore, Ming-Tsung Lee, and Yuet-Kin Leung -- Vitamin D and prostate cancer / Jung-Sun Kim, Justin M. Roberts, Nancy L. Weigel -- HDAC6 regulation of androgen signaling in prostate cancer / Junkui Ai, Zhou Wang -- Beyond the cell cycle : implications of D-type cyclin deregulation in prostate cancer / Michael A. Augello, William F. Ostrander Jr., Karen E. Knudsen -- Cell death. Role of par-4 in prostate cancer / Nidhi Shukla, Nikhil K. Hebbar, Vivek M. Rangnekar -- Autophagy and prostate cancer therapeutics / Hsing-Jien Kung, Chun Changou, Hao G. Nguyen, Joy C. Yang, Christopher P. Evans, Richard J. Bold, and Frank Chuang.
  • 2007 Springer
    edited by Leland W.K. Chung, William B. Isaacs, and Jonathan W. Simons ; foreword by Donald S. Coffey.
    Xenograft models of human prostate cancer -- The pathology of human prostatic atrophy and inflammation -- Tissue microarrays in prostate cancer research -- Prostate (cancer) stem cells -- Cancer-host interactions: a paradigm shift brings new understanding and new opportunities -- Androgen receptor function in prostate cancer progression -- Hedgehog signaling in development and cancer -- Cholesterol, cell signaling, and prostate cancer -- Gene therapy for advanced prostate cancer -- Role of transforming growth factor-ss in immunotherapy of prostate cancer -- Biology and therapeutic basis of prostate cancer bone metastasis -- Molecular imaging: noninvasive strategies to visualize gene expression in living subjects -- Quantum dot nanotechnology for prostate cancer research -- Expression profiling of prostate cancer progression -- Somatic alterations in prostate cancer progression -- Linkage studies of prostate cancer families to identify susceptibility genes -- Somatic DNA methylation changes and prostatic carcinogenesis -- Telomeres, telomerase, chromosome stability, and prostate cancer -- Racial differences in prostate cancer mortality -- Radiotherapy for the treatment of locally advanced prostate cancer -- Recombinant antibody candidates for treatment of prostate cancer -- Differentiation agents and epigenomic therapies: an overview and potential use for prostate cancer -- Taxane-based chemotherapy for prostate cancer -- Co-targeting therapeutics for hormone refractory prostate cancer -- Intercellular targets of prostate cancer -- Novel and efficient translational clinical trial designs in advanced prostate cancer.
  • 2002 Ovid
    editors, Philip W. Kantoff, Peter R. Carroll, Anthony V. D'Amico ; section editors, Ronald K. Ross, John T. Isaacs, Howard I. Scher.
    Also available: Print – 2002
  • 2008 Springer
    edited by Richard G. Pestell, Marja T. Nevalainen ; foreword by Michael Milken.
    Histopathology and molecular biology of prostate atrophy: a lesion associated with inflammation, prostate intraepithelial neoplasia, and prostate cancer -- Epigenetic gene silencing in prostate cancer -- Inherited genetic changes in prostate cancer -- Prostate molecular oncogenesis: gene deletions and somatic mutations -- Somatic genetic changes in prostate cancer: androgen receptor alterations -- Androgen receptor in prostate cancer progression -- Epigenetic modification and aceylation of androgen receptor regulate prostate cellular growth -- Estrogen receptor a [alpha] and b [beta] in the regulation of normal and malignant prostate epithelium -- Estrogen action in normal prostate epithelium and in prostate cancer -- Hypoxia-inducible factor 1 in the angiogenesis of prostate cancer -- Signal transduction by the Ras-MAP kinase pathway in prostate cancer progression -- Transcription factors STAT5 and STAT3: survival factors for prostate cancer cells -- Role of P13K-Akt and PTEN in the growth and progression of prostate cancer -- New perspectives in prediction of clinical outcome of prostate cancer; TMPRSS2-ETS gene fusion in prostate cancer -- New directions in radiation therapy of prostate cancer: brachytherapy and intensity-modulated radiation therapy -- The current knowledge of hormonal therapy in the treatment of prostate cancer -- Advances in surgical intervention of porstate cancer: comparison of the benefits and pitfalls of retropubic, perineal, and laparoscopic radical prostatectormy -- Targeted therapy trials for prostate cancer -- New perspectives on chemotherapy in prostate cancer -- Concluding remarks: the future of prostate cancer.
  • 2013 Springer
    Ashutosh Tewari, editor.
    Prostate cancer is the commonest male cancer with over 5 million survivors in US alone. Worldwide, the problem is staggering and has attracted significant attention by media, scientists and cancer experts. Significant research, discoveries, innovations and advances in treatment of this cancer have produced voluminous literature which is difficult to synthesize and assimilate by the medical community. Prostate Cancer: A Comprehensive Perspective is a comprehensive and definitive source which neatly resolves this problem. It covers relevant literature by leading experts in basic science, molecular biology, epidemiology, cancer prevention, cellular imaging, staging, treatment, targeted therapeutics and innovative technologies. Prostate Cancer: A Comprehensive Perspective, is a valuable and timely resource for urologists and oncologists.
  • 2015 Springer
    René Sotelo, Juan Arriaga, Raed A. Azhar, Inderbir S. Gill, editors.
    1. Introduction -- 2. An Appointment with the Urologist -- 3. Prostate-Specific Antigen (PSA) -- 4. Prostate Biopsy -- 5. Prostatitis- Pelvic Pain -- 6. Benign Prostatic Hyperplasia -- 7. Prostate Cancer -- 8. How to Get a Second Opinion.
  • 2013 Springer
    J. Stephen Jones, editor.
    Based on the highly successful first edition of Prostate Biopsy: Indications, Techniques, and Complications, this new volume presents new concepts that have emerged in answer to current questions from its audience. Many new perspectives and technologies are presented, many from the authors' internationally recognized work on the topic. Substantial developments in techniques and complications are explored in detail. The chapter authors comprise a complete spectrum of specialists in their respective subject areas. All authors are internationally accepted as the premier authorities on their chosen topics. Prostate Cancer Diagnosis: PSA, Biopsy, and Beyond presents new data on the controversial issue of PSA screening and thresholds as indication to perform biopsy. Office based transrectal saturation biopsy is covered in detail. Other topics explored include template guided biopsy and image-guided biopsy as well as a completely new paradigm for prevention of complications.Prostate Cancer Diagnosis: PSA, Biopsy, and Beyond will be of great value and utility to all practicing urologists.
  • 2016 Springer
    Nelson N. Stone, E. David Crawford, editors.
    This comprehensive text provides a complete description of the newest technologies to diagnose and manage the most common prostate cancer diagnosed today: low risk disease. The book reviews new data about genetic markers, transperineal mapping biopsy and mpMRI, how to apply each of these technologies in patients with elevated PSA, when a prior prostate biopsy performed by the standard TRUS method is negative, and, in cases where low risk disease is already diagnosed, how to differentiate those men who might harbor more aggressive disease from those who do not. Over 75% of newly diagnosed prostate cancer meets the criteria for low risk disease which has created a dilemma for both patients and clinicians because of the inaccuracy of the standard TRUS biopsy method. Active surveillance programs have been initiated and are reviewed. How the new technologies impact surveillance programs are addressed. Clinical stage designation is updated and a new intra-prostatic staging system is discussed. Prostate biopsy techniques utilizing transrectal ultrasound, transperineal mapping, elastography and mpMRI are compared. Finally, utilization of these new technologies in the application of focal therapy is reviewed. The Prostate Cancer Dilemma will serve as a valuable resource for clinicians, surgeons and researchers with an interest in early prostate cancer. Chapters are written by experts in their fields and include the most up-to-date scientific and clinical information as well as links to procedural video content.
  • 2014 Springer
    Jack Cuzick, Mangesh A. Thorat, editors.
    Prostate cancer is by far the most common cancer in men and the second leading cause of death due to cancer. It comprises a mixed group of tumours displaying varying clinical behaviour: while some have a very aggressive course, others are rather indolent. Prevention of prostate cancer and discrimination between aggressive and indolent forms are important clinical goals, and the acquisition of significant new evidence on means of achieving these aims makes this book particularly timely. A wide range of topics are covered by leading authorities in the field. The biology and natural history of prostate cancer are reviewed, and the role of lifestyle and dietary factors, assessed. Detailed attention is paid to risk prediction biomarkers and to the role of novel high-throughput nucleic acid-based technologies in improving risk prediction and thereby allowing tailored approaches to cancer prevention. Potential means of chemoprevention of prostate cancer are also reviewed in depth, covering the very positive new data on the impact of aspirin as well as evidence regarding 5-reductase inhibitors, DFMO, and lycopene. Guidance is provided on the differentiation of aggressive from indolent disease, and the policy and research implications of recent findings are examined. This book will be of interest to both clinicians and researchers.
  • 2013
    California HealthCare Foundation.
  • 2013 Springer
    Stefania Staibano, editor.
    The aim of this book will be to contribute to the education of a new generation of experts in urology, molecular biology, pathology and oncology, offering them sufficient knowledge in basic and translational research to be fluency in the web of interacting networks playing a role in prostate cancer development, progression, metastasis and drug-resistance. The volume will cover the latest innovative researches in prostate cancer, with particular emphasis to the state-of-the-art analysis technologies that are essential for the accurate identification of molecular targets for disease diagnosis, molecular mechanisms of tumorigenesis, markers for susceptibility, molecular-based prognostic prevision, characterization of biomarkers of drug efficacy and drug resistance, validation of new therapeutics and diagnostics. Current advancements on the intersecting data concerning transcriptomes, proteomes, and the molecular techniques referred as "omes, will be reported and discussed.
  • 2015 Springer
    Christopher R. Porter, Erika M. Wolff, editors.
    Introduction -- History of Prostate Ultrasound -- Applied Anatomy of the Male Pelvis -- Basic Physics of Diagnostic Ultrasound -- Advanced Prostate Imaging: Correlating Prostate Anatomy with MRI and MRI/Ultrasound Fusion -- Prostate Ultrasound Artifacts and How to Fix Them -- Male Infertility And Prostate Ultrasound -- Application of Prostate Ultrasound for Benign Prostate Hyperplasia and Male Urinary Stress Incontinence -- Application of Prostate Ultrasound for Prostate Biopsy -- Prostate Ultrasound Complications and Patient Safety -- Imaging the Prostate with Quantitative Ultrasound: Implications for Guiding Biopsies, Targeting Focal Treatment, and Monitoring Therapy -- Prostate Elastography.
  • 2016 Springer
    Tommaso Cai, Truls E. Bjerklund Johansen, editors.
    Introduction and aim of the book -- Epidemiology and microbiological considerations: what's new?.- The diagnostic approach to patient with prostatitis-like symptoms: what do we have to do? -- Classification of prostatitis: what is the clinical usefulness? -- Imaging studies: what is their role? -- Treatment of bacterial prostatitis: the pharmacologist's point of view -- Treatment of non-bacterial prostatitis: what's new? -- The role of phythoterapy in the management of prostatitis patients -- Management of infective complications following prostate biopsy -- The contribution of prostate infection and inflammation to BPH and cancer -- The role of STD pathogens in bacterial prostatitis patients -- Andrologic sequelae in prostatitis patients -- The role of chronic prostatitis in male infertility: is there a relationship? -- Thoughtless treatment of prostatitis is malpractice, sometimes even a forensic issue -- The prostatitis patient: Questions and Answers.
  • 2016 Springer
    Asif Muneer, Ian Pearce, David Ralph, editors.
    Introduction to Prosthetic Devices -- History of Prosthetic Surgery in Urology -- Infection and biofilms -- Patient selection and assessment -- Patient Consent for Surgery -- Theatre preparation and equipment -- Patient preparation for surgery -- Urinary Catheters, Drains and Stomas -- Ureteric Stents -- Prostatic Stents -- Testicular Prosthesis -- Surgery for female urinary incontinence -- Sacral neuromodulation -- The artificial urinary sphincter -- Male urethral slings -- Injectable agents in urology -- Penile reconstructive surgery using grafts -- Penile prosthesis surgery -- Complications of penile prosthesis surgery -- Future developments in prosthetic surgery.
  • Google Books
    by Howard B. Woolston, Ph.D.
    Also available: Print – v. 1, 1921-.
  • 2010 Springer
    Domenico Ribatti.
  • 2009 Springer Protocols
    edited by Toni M. Antalis, Thomas H. Bugge.
    1. Delineating protease functions during cancer development / Nesrine I. Affara, Pauline Andreu, and Lisa M. Coussens -- 2. Proteolytic systems: constructing degradomes / Gonzalo R. Ordóñez ... [et al.] -- 3. Microarrays for protease detection in tissues and cells / Kamiar Moin ... [et al.] -- 4. Positional scanning synthetic combinatorial libraries for substrate profiling / Eric L. Schneider and Charles S. Craik -- 5. Mixture-based peptide libraries for identifying protease cleavage motifs / Benjamin E. Turk -- 6. High throughput substrate phage display for protease profiling / Boris Ratnikov, Piotr Cieplak, and Jeffrey W. Smith -- 7. Imaging specific cell surface protease activity in living cells using reengineered bacterial cytotoxins / John P. Hobson ... [et al.] -- 8. Cell-based identification of natural substrates and cleavage-sites for extracellular proteases by SILAC proteomics / Magda Gioia, Leonard J. Foster, and Christopher M. Overall -- 9. Optical proteolytic beacons for in vivo detection of matrix metalloproteinase activity -- J. Oliver McIntyre and Lynn M. Matrisian -- 10. Dissecting the urokinase activation pathway using urokinase-activated anthrax toxin / Shihui Liu ... [et al.] -- 11. On-demand cleavable linkers for radioimmunotherapy / Pappanaicken R. Kumaresan, Juntao Luo, and Kit S. Lam.
  • 2011 Springer
    Nathalie Vergnolle, Michel Chignard, editors.
    Also available: Print – 2011
  • v. 3-, 2005- Springer
  • 2006 Springer
    edited by Uwe Lendeckel and Nigel M. Hooper.
    1. Protease-Activated Receptors in Gastrointestinal Function and Disease / Nigel W. Bunnett and Graeme S. Cottrell -- 2. Matrix Metalloproteinases in Gastric Cancer / Nikhil I. Khushalani and Nithya Ramnath -- 3. Proteases in Helicobacter pylori-Mediated Diseases / Thomas Wex, Michael Zack, and Peter Malfertheiner -- 4. Proteases in Pancreatic Disease / Avinash Sewpaul, Jeremy J. French, and Richard M. Charnley -- 5. PAR in the Pathogenesis of Pain in Pancreatic Disease / Pankaj J. Pasricha -- 6. Importance of the Local Renin-Angiotensin System in Pancreatic Disease / Po Sing Leung -- 7. Hepatitis C Viral Proteases And Inhibitors / Mingjun Huang, Avinash Phadke and Atul Agarwal -- 8. Angiotensin Converting Enzyme in the Pathophysiology of Liver Fibrosis / Yao Hong Wei -- 9. Matrix Metalloproteinases in Chronic Liver Disease and Liver Transplantation / Hein W. Verspaget, Johan P. Kuyvenhoven, Cornelis F.M. Sier, Bart van Hoek -- 10. MMPs and ADAMs in Inflammatory Bowel Disease / Alicja Wiercinska-Drapalo, Jerzy Jaroszewicz, Anna Parfieniuk, Anna Moniuszko -- 11. Chemokines and Matrix Metalloproteinases in Colorectal Cancer / Gayle G. Vaday and Stanley Zucker -- 12. Angiotensin-Converting Enzyme (ACE) in Gut Inflammation / Fernando Magro -- 13. Intestinal Apical Protein Transport in Health and Disease / Stephan von Hörsten, Michael Krahn, Nadine Frerker, Anja Gemeinhardt, Dennis Schwab, Silvia Slesiona, Hassan Naim, and Marwan Alfalah.
  • 2013 Springer
    edited by Sajal Chakraborti, Naranjan S. Dhalla.
    In view of rapidly growing research in the deregulation of proteases and their impact in human health and diseases, this book will highlight existing and emerging research in this exciting area. In-depth critical state-of-the-art reviews will be written by established investigators on proteases dysfunctions associated with pathogenesis of different diseases that are known to occur due to deregulation of proteolytic systems. Multidisciplinary approaches demonstrating biochemical and signal transduction mechanisms associated with deregulation of proteases leading to manifestation of the diseases.
  • 2005 Springer
    edited by Uwe Lendeckel and Nigel M. Hooper.
  • 2006 Springer
    edited by Leonidas Stefanis, Jeffrey N. Keller.
  • 2006
    edited by Oliver Schmoll ... [et al.].
    Status: Not Checked OutLane Catalog Record
  • 2002 AAMC
    Task Force on Financial Conflicts of Interest in Clinical Research.
  • 2007 WHO
    World Health Organization.
    Also available: Print – 2007
  • 2010
    Lihan Sun.
    The nearly 9 million incidences of myocardial infarction (MI) and the resultant heart failure in the United States alone call for a continued need for the development of novel therapeutics. However, the molecular basis of these diseases is highly complex and awaits further elucidation. Our lab has a long-standing interest in determining the role of protein kinase C (PKC) in cardiovascular diseases. Elevated expression of alpha, beta, epsilon and deltaPKCs is associated with cardiac dysfunction in failing murine and human hearts. Moreover, genetic and pharmacological modulations of PKC activities exert profound impact on the state of these diseases. However, characterization of the specific role of each PKC isozyme was hampered by the lack of isozyme-selective PKC regulators. To this end, Mochly-Rosen and co-workers have rationally designed and developed isozyme-selective peptide activators and inhibitors of PKC that have enabled us to examine the role of each PKC isozyme in any biological system. Using an epsilonPKC-selective inhibitor, we found that sustained inhibition of epsilonPKC suppressed excessive cardiac fibrosis and preserved cardiac function in a rat model of hypertension-induced heart failure, in vivo. To uncover the mechanistic link between epsilonPKC and cardiac fibrosis, I showed that activation of epsilonPKC increased the activity matrix metalloproteinase-2 (MMP-2), a critical protease that degrades the extracellular matrix to facilitate cardiac fibrosis. Further, using the epsilonPKC inhibitor and cardiac fibroblasts that lack epsilonPKC, I discovered that histone deacetylase 6 (HDAC6), a cytosolic enzyme that deaceylates alpha-tubulin, participates in epsilonPKC modulation of MMP-2 activity during cardiac fibrosis. These results suggest that the epsilonPKC-selective inhibitor can be a potential therapeutic for the treatment of heart failure. Aldehyde dehydrogenase 2 (ALDH2) was identified by our group as a mitochondrial substrate for epsilonPKC that confers cardioprotection from ischemic injury. ALDH2 activation during MI is cardioprotective, because it oxidizes and thus removes toxic aldehydes that accumulate due to lipid peroxidation during ischemia-reperfusion. Since these aldehydes form protein adducts that inactive many cellular enzymes, they contribute to non-reversible damage to the ischemic myocardium. A recent study discovered that ALDH2 is required for nitroglycerin bioactivation, in vivo, but its enzymatic activity is inhibited by prolonged treatment with nitroglycerin. This has prompted us to determine potential risks associated with nitroglycerin tolerance in association with the role that ALDH2 has in cardiac protection. The clinical implications here are of special interest to us, because any risks pertinent to nitroglycerin treatment, if validated, can affect millions of patients with cardiac diseases. Therefore, I set off to determine whether sustained nitroglycerin treatment increases injury to the ischemic myocardium using a rat model of myocardial infarction (MI). I confirmed that sustained nitroglycerin treatment, as might be given to patients with angina pectoris, inhibited ALDH2 activity in the rat myocardium, in vivo. Further, I found that continuous treatment of nitroglycerin resulted in more than 2-fold increase in infarct size and worsened cardiac function after MI, in vivo. I then used Alda-1, a selective ALDH2 activator our group discovered, to assess whether activation of ALDH2 could undo the nitroglycerin-induced cardiac injury. Indeed, concomitant treatment with Alda-1 and nitroglycerin inhibited nitroglycerin-induced increase in infarct size and restored post-MI cardiac function. This finding poses a challenge to the prevalent clinical practice: patients, under sustained nitroglycerin therapy for the management of angina pectoris, are at risk of increased cardiac damage if they develop an MI during the nitroglycerin treatment. My animal studies suggest that if Alda-1 is given together with nitroglycerin, it can reduce cardiac damage caused by nitroglycerin tolerance. Finally, to determine the mechanism underlying the role of nitroglycerin and Alda-1 in MI injury, I demonstrated that Alda-1 prevented nitroglycerin-induced inactivation of ALDH2 and the resultant elevation of protein carbonylation, a hallmark of toxic aldehydic adducts, in the myocardium. The result substantiates a health mechanism for the heart: loss of control over oxidative stress leads to an injured myocardium and a simple correction of that function undoes the bad.
  • 2013 Springer Protocols
    edited by Sandra B. Hake, Christian J. Janzen.
    Validation of protein acetylation by mass spectrometry / Barry M. Zee and Benjamin A. Garcia -- Application of the CIRAD mass spectrometry approach for lysine acetylation site discovery / Caroline A. Evans [and others] -- Application of the MIDAS approach for analysis of lysine acetylation sites / Caroline A. Evans [and others] -- Application of high content biology to yield quantitative spatial proteomic information on protein acetylations / Bernard M. Corfe [and others] -- Towards the N-Terminal acetylome : an N-Terminal acetylated peptide enrichment method using CNBr-activated sepharose resin / Xumin Zhang and Peter Højrup -- Identification and analysis of o-acetylated sialoglycoproteins / Chandan Mandal and Chitra Mandal -- HPLC-based quantification of in vitro N-terminal acetylation / Rune H. Evjenth [and others] -- Separation and purification of multiply acetylated proteins using cation-exchange chromatography / Romeo Papazyan and Sean D. Taverna -- In-gel N-acetylation for the quantification of the degree of protein in vivo N-terminal acetylation / Petra Van Damme [and others] -- Computational prediction of lysine acetylation proteome-wide / Amrita Basu -- Generation and characterization of pan-specific anti-acetyllysine antibody / Wei Xu and Shimin Zhao -- Using functional proteome microarrays to study protein lysine acetylation / Jin-ying Lu [and others] -- Quantitation of nucleosome acetylation and other histone posttranslational modifications using microscale NU-ELISA / Bo Dai, Charles Giardina, and Theodore P. Rasmussen -- Preparing semisynthetic and fully synthetic histones H3 and H4 to modify the nucleosome core / John C. Shimko [and others] -- Production of amino-terminally acetylated recombinant proteins in E. coli / Matthew Johnson, Michael A. Geeves, and Daniel P. Mulvihill -- Identification of lysine acetyltransferase substrates using bioorthogonal chemical proteomics / Markus Grammel and Howard C. Hang -- Nonradioactive in vitro assays for histone deacetylases / Alexander-Thomas Hauser, Julia M. Gajer (nee Wagner), and Manfred Jung -- Fluorescence-based acetylation assay using thiol-sensitive probes / Tielong Gao, Chao Yang, and Yujun George Zheng -- Analysis of protein acetyltransferase structure-function relation by surface-enhanced raman scattering (SERS): a tool to screen and characterize small molecule modulators / Mohammed Arif [and others].
  • 2014 Springer Protocols
    edited by Richard J. Giannone, Andrew B. Dykstra.
    1D4 : a versatile epitope tag for the purification and characterization of expressed membrane and soluble proteins / Laurie L. Molday and Robert S. Molday -- Affinity purification of heme-tagged proteins / Wesley B. Asher and Kara L. Bren -- Purification of a recombinant protein with cellulose-binding module 3 as the affinity tag / Dongmei Wang and Jiong Hong -- Purification of E. coli proteins using a self-cleaving chitin-binding affinity tag / Michael J. Coolbaugh and David W. Wood -- Simplified protein purification using an autoprocessing, inducible enzyme tag / Aimee Shen -- SUMO as a solubility tag and in vivo cleavage of SUMO fusion proteins with UlP1 / Dennis Kuo, Minghua Nie, and Albert J Courey -- Rescuing aggregation-prone proteins in Escherichia coli with a dual His6-MBP tag / Danielle Needle and David S. Waugh -- Expression, purification, and immobilization of recombinant tamavidin 2 fusion proteins Yashimitsu Takakura, Naomi Oka, and Masako Tsunashima -- Use of tandem affinity chromatography for purification of cannabinoid receptor CB2 / Silvia C. Locatelli-Hoops and Alexei A. Yeliseev -- Detection of protein-protein interactions using tandem affinity purification / Ian Goodfellow and Dalan Bailey -- An improved in vivo biotinylation strategy combined with FLAG and antibody based approaches for affinity purification of protein complexes in mouse embryonic stem cells / Francesco Faiolo [and three others] -- Purification of recombinant proteins with a multifunctional GFP tag / Takashi Murayama and Takuya Kobayashi -- Targeted purification of SnAvi-tagged proteins / Ursula Schäffer, Ralf Baumeister, and Ekkehard Schulze -- An efficient fluorescent protein-based multifunctional affinity purification approach in mammalian cells / Hanhui Ma [and three others] -- Bimolecular affinity purification : a variation of TAP with multiple applications / Petro Starokadomskyy and Ezra Burstein.
  • 2012 Springer
    J. Robin Harris, editor.
    Introduction and technical survey: Protein aggregation and fibrillogenesis -- Fibril formation by short synthetic peptides -- In vitrooligomerization and fibrillogenesis of amyloid-beta peptides -- Tau fibrillogenesis -- Prion protein aggregation and fibrillogenesisin vitro -- Alpha-synuclein aggregation and modulating factors -- Pathological self-aggregation of [beta](2)-microglobulin: A challenge for protein biophysics -- Islet amyloid polypeptide: Aggregation and fibrillogenesisin vitroand its inhibition -- Mechanisms of transthyretin aggregation and toxicity -- Fibrillogenesis of huntingtin and other glutamine containing proteins -- Aggregation and fibrillogenesis of proteins not associated with disease: a few case studies -- Experimental inhibition of peptide fibrillogenesis by synthetic peptides, carbohydrates and drugs -- Experimental inhibition of fibrillogenesis and neurotoxicity by amyloid-beta (abeta) and other disease-related peptides/proteins by plant extracts and herbal compounds -- Alzheimer's disease -- Modeling the polyglutamine aggregation pathway in Huntington's disease: from basic studies to clinical applications -- Parkinson's disease -- Human prion diseases: From kuru to variant Creutzfeldt-Jakob disease -- Animal prion diseases -- [beta](2)-Microglobulin amyloidosis -- Systemic AA amyloidosis -- Familial amyloidotic polyneuropathy and transthyretin -- The challenge of systemic immunoglobulin light-chain amyloidosis (AL).
  • 2016 Springer Protocols
    edited by David Eliezer.
    Semisynthesis and enzymatic preparation of post-translationally modified α-Synuclein / Bruno Fauvet and Hilal A. Lashuel -- Isotope-labeled amyloids via synthesis, expression, and chemical ligation for use in FTIR, 2D IR, and NMR studies / Tianqi O. Zhang ... [et al.] -- Intermolecular paramagnetic relaxation enhancement (PRE) studies of transient complexes in intrinsically disordered proteins / Maria K. Janowska and Jean Baum -- Detection of helical intermediates during amyloid formation by intrinsically disordered polypeptides and proteins / Andisheh Abedini, Ping Cao, and Daniel P. Raleigh -- Fluorescence correlation spectroscopy : a tool to study protein oligomerization and aggregation in vitro and in vivo / Bankanidhi Sahoo, Kenneth W. Drombosky, and Ronald Wetzel -- Deep UV resonance raman spectroscopy for characterizing amyloid aggregation / Joseph D. Handen and Igor K. Lednev -- Analyzing tau aggregation with electron microscopy / Carol J. Huseby and Jeff Kuret -- Characterization of amyloid oligomers by electrospray ionization-ion mobility spectrometry-mass spectrometry (ESI-IMS-MS) / Charlotte A. Scarff, Alison E. Ashcroft, and Sheena E. Radford -- Formation and characterization of α-Synuclein oligomers / Wojciech Paslawski, Nikolai Lorenzen, and Daniel E. Otzen -- Fluorescence methods for unraveling oligomeric amyloid intermediates / Niels Zijlstra, Nathalie Schilderink, and Vinod Subramaniam -- Preparation of amyloid fibrils for magic-angle spinning solid-state NMR spectroscopy / Marcus D. Tuttle ... [et al.] -- Spin labeling and characterization of tau fibrils using electron paramagnetic resonance (EPR) / Virginia Meyer and Martin Margittai -- Preparation of crystalline samples of amyloid fibrils and oligomers / Asher Moshe, Meytal Landau, and David Eisenberg -- Quenched hydrogen exchange NMR of amyloid fibrils / Andrei T. Alexandrescu -- Studying the early stages of protein aggregation using replica exchange molecular dynamics simulations / Joan- Emma Shea and Zachary A. Levine -- Computational methods for structural and functional studies of Alzheimer's amyloid ion channels / Hyunbum Jang ... [et al.] -- Analyzing ensembles of amyloid proteins using Bayesian statistics / Thomas Gurry ... [et al.] -- In vitro studies of membrane permeability induced by amyloidogenic polypeptides using large unilamellar vesicles / Ping Cao and Daniel P. Raleigh -- Cell models to study cell-to-cell transmission of α-Synuclein / Eun-Jin Bae, He-Jin Lee, and Seung-Jae Lee -- Preparation of amyloid fibrils seeded from brain and meninges / Kathryn P. Scherpel ... [et al.].
  • 2006 Karger
    editors, Jacques Rigo, Ekhard E. Ziegler.
    Long-term consequences of early feeding on later obesity risk / Koletzko, B. -- Energy requirements of infants and children / Butte, N.F. -- Protein requirements of infants and children / Garlick, P.J. -- Growth of breast-fed and formula-fed infants / Ziegler, E.E. -- Body composition during the first year of life / Rigo, J. -- Dietary reference intakes : concepts and approaches underlying protein and energy requirements / Yates, A.A. -- Intestinal amino acid metabolism in neonates / Van Goudoever, J.B. ... [et al.] -- Amino acid requirements of infants and children / Pencharz, P.B., Ball, R.O. -- Effects of high protein intakes / Axelsson, I. -- Physiology in food intake regulation : interaction with dietary components / Anderson, G.H., Aziz, A., Abou Samra, R. -- Complementary food : international comparison on protein and energy requirement/intakes / Agostoni, C., Riva, E., Giovannini, M. -- What is the optimal age for introduction of complementary foods? / Dewey, K.G. -- Recent issues in energy-protein malnutrition in children / Desjeux, J.-F. -- Protein quality and quantity in cow's milk-based formula for healthy term infants : past, present and future / Macé, K. ... [et al.] -- Recombinant human milk proteins / Lönnerdal, B. Long-term consequences of early feeding on later obesity risk / B. Koletzko -- Energy requirements of infants and children / N.F. Butte -- Protein requirements of infants and children / P.J. Garlick -- Growth of breast-fed and formula-fed infants / E.E. Ziegler -- Body composition during the first year of life / J. Rigo -- Dietary reference intakes: concepts and approaches underlying protein and energy requirements / A.A. Yates -- Intestinal amino acid metabolism in neonates / J.B. van Goudoever ... [et al.] -- Amino acid requirements of infants and children / P.B. Pencharz, R.O. Ball -- Effects of high protein intakes / I. Axelsson -- Physiology in food intake regulation: interaction with dietary components / G.H. Anderson, A. Aziz, R.A. Samra -- Complementary food: international comparison on protein and energy requirement/intakes / C. Agostoni, E. Riva, M. Giovannini -- What is the optimal age for introduction of complementary foods? / K.G. Dewey -- Recent issues in energy-protein malnutrition in children / J.-F. Desjeux -- Protein quality and quantity in cow's milk-based formula for healthy term infants: past, present and future / K. Macé ... [et al.] -- Recombinant human milk proteins / B. Lönnerdal.
  • 2015 Springer Protocols
    edited by Anna S. Kashina.
    Protein arginylation: over 50 years of discovery / Anna S. Kashina -- Recollection of how we came across the protein modification with amino acids by aminoacyl trna-protein transferase / Hideko Kaji and Akira Kaji -- Arginyltransferase: a personal and historical perspective / Ricahrd L. Soffer -- Arginylation in a partially purified fraction of 150k x g supernatants of axoplasm and injured vertebrate nerves / Nicholas A. Ingoglia -- Preparation of ATE1 enzyme from native mammalian tissues / Anna S. Kashina -- Correlated measurement of endogenous ATE1 activity on native acceptor proteins in tissues and cultured cells to detect cellular aging / Hideko Kaji and Akira Kaji -- Assaying the posttranslational arginylation of proteins in cultured cells / Mauricio R. Galiano and Marta E. Hallak -- Assaying ATE1 activity in yeast by [beta]-Gal degradation / Anna S. Kashina -- Bacterial expression and purification of recombinant arginyltransferase (ATE1) and arg-tRNA synthetase (RRS) for arginylation assays / Junling Wang and Anna S. Kashina -- Assaying ATE1 activity in vitro/ Junling Wang and Anna S. Kashina -- High-throughput arginylation assay in microplate format / Sougata Sha, Junling Wang and Anna S. Kashina -- Assay of arginyltransferase activity by a fluorescent HPLC method / Koichi Takao -- Identification of arginylated proteins by mass spectrometry / Anna S. Kashina and Jon R. Yates III -- Analysis of arginylated peptides by subtractive edman degradation / Anna S. Kashina and Jon R. Yates III -- Transferase-mediated labeling of protein N-termini with click chemistry handles / Anne M. Wagner [and four others] -- Applying arginylation for bottom-up proteomics / H. Alexander Ebhardt -- Development of new tools for the studies of protein arginylation / Anna S. Kashina.
  • 2010 ScienceDirect
    M. Michael Gromiha.
  • 2015 Springer Protocols
    edited by Brendan P. Orner.
    Encapsulation of nanoparticles in virus protein shells / Irina B. Tsvetkova and Bogdan G. Dragnea -- Use of protein cages as a template for confined synthesis of inorganic and organic nanoparticles / Masaki Uchida [and three others] -- Ferritin encapsulation and templated synthesis of inorganic nanoparticles / Katherine W. Pulsipher and Ivan J. Dmochowski -- Determining the relaxivity values of protein cage-templated nanoparticles using magnetic resonance imaging / Barindra Sana and Sierin Lim -- Computationally assisted engineering of protein cages / Maziar S. Andrejani and Brendan P. Orner -- Recombinant expression and purification of "virus-like" bacterial encapsulin protein cages / W. Frederik Rurup, Jeroen J.L.M. Cornelissen, and Melisa S.T. Koay -- Production of bacterial microcompartments / Jonathan K. Lassila -- Detection of protein cage assembly with bisarsenic fluorescent probes / Thomas A. Cornell and Brendan P. Orner -- Determining the role of metal binding in protein cage assembly / Anne Grove, Ambuj K. Kushwaha, and Khoa H. Nguyen -- Differential scanning calorimetry to quantify the stability of protein cages / Yu Zhang and Maziar S. Ardejani -- Material properties of viral nanocages explored by atomic force microscopy / Mariska G.M. van Rosmalen, Wouter H. Roos, and Gijs J.L. Wuite -- Computational mechanics of viral capsids / Melissa G. Gibbons, Luigi E. Perotti, and William S. Klug.
  • 2011 Springer Protocols
    edited by Dermot Walls and Sinéad T. Loughran.
    A digest of protein purification -- Gel-filtration chromatography -- Immunoaffinity chromatography -- Avoiding proteolysis during protein chromatography -- Scale-up of protein purification : Downstream processing issues -- Phage display : A powerful technology for the generation of high specificity affinity reagents from alternative immune sources -- Engineering protein stability -- Microfluidics in protein chromatography -- Tagging recombinant proteins to enhance solubility and aid purification -- Storage and lyophilisation of pure proteins -- Differential precipitation and solubilization of proteins -- Ion-exchange chromatography : Basic principles and application to the partial purification of soluble mammalian prolyl oligopeptidase -- Protein quantitation and analysis of purity -- Purification of proteins fused to glutathione S-transferase -- Purification of proteins fused to maltose-binding protein -- Purification of proteins from baculovirus-infected insect cells -- Purification of poly-histidine-tagged proteins -- Immobilized metal affinity chromatography/reversed-phase enrichment of phosphopeptides and analysis by cid/etd tandem mass spectrometry -- Tag removal by site-specific cleavage of recombinant fusion proteins -- Purification of antibodies using affinity chromatography -- Optimized generation of high-affinity, high-specificity single-chain Fv antibodies from multiantigen immunized chickens -- Measuring protein-protein interactions using biacore -- Ultra-performance liquid chromatography-mass spectrometry of proteins -- Hydrophobic interaction chromatography -- Fast protein liquid chromatography -- Shotgun proteomics : A qualitative approach applying isoelectric focusing on immobilized pH gradient and LC-MS/MS -- Shotgun proteomics : A relative quantitative approach using off-gel electrophoresis and LC-MS/MS -- Clinical proteomics : Liquid chromatography-mass spectrometry purification systems -- Strategies for the purification of membrane proteins -- A multi-step chromatographic strategy to purify three fungal endo-[beta]-glucanases.
  • 2014 Springer
    Ke-li Han, Xin Zhang, Ming-jun Yang, editors.
    "This book discusses how biological molecules exert their function and regulate biological processes, with a clear focus on how conformational dynamics of proteins are critical in this respect. In the last decade, the advancements in computational biology, nuclear magnetic resonance including paramagnetic relaxation enhancement, and fluorescence-based ensemble/single-molecule techniques have shown that biological molecules (proteins, DNAs and RNAs) fluctuate under equilibrium conditions. The conformational and energetic spaces that these fluctuations explore likely contain active conformations that are critical for their function. More interestingly, these fluctuations can respond actively to external cues, which introduces layers of tight regulation on the biological processes that they dictate. A growing number of studies have suggested that conformational dynamics of proteins govern their role in regulating biological functions, examples of this regulation can be found in signal transduction, molecular recognition, apoptosis, protein / ion / other molecules translocation and gene expression"--Publisher's description.
    Also available: Print – 2014
  • 2014 Springer
    Anthony P. Nicholas, Sanjoy K. Bhattacharya, editors.
    Physiological pathways of PAD activity and citrullinated epitope generation -- from citrullination to specific immunity and disease in rheumatoid arthritis -- The role of citrullinated proteins in the pathophysiology of rheumatoid arthritis -- Protein citrullination: the link between rheumatoid arthritis and periodontitis? -- From genes and environment to anti-culture immunity in rheumatoid arthritis: The role of the lungs -- Neutrophils and their contribution to autoimmunity in rheumatoid arthritis -- Deimination in skin and regulation of PAD expression in keratinocytes -- Importance of citrullination on hair protein molecular assembly during trichocytic differentiation -- Deimination in the peripheral nervous system: A wallflower existence -- Deimination in multiple sclerosis and experimental autoimmune encephalomyelitis -- Protein hypercitrullination in CNS demyelinating disease reversed by PAD inhibition -- Deimination in prion diseases -- Deimination in Alzheimer's disease -- Ongoing studies of deimination in neurodegenerative diseases using the F95 antibody -- The role of protein deimination in epigenetics -- Identifying citrullination sites by mass spectroscopy -- Homocitrulline\U+2014\an analogue and confounder related to citrulline -- Picking the PAD lock: Chemical and biological approaches to identify PAD substrates and inhibitors.
  • 2014 Springer Protocols
    edited by Valentin Köhler.
    De novo design of stable [alpha]-helices / Alexander Yakimov, Georgy Rychkov, and Michael Petukhov -- Design of monomeric water-soluble [Beta]-hairpin and [Beta]-sheet peptides/ M. Angeles Jiménez -- Combination of theoretical and experimental approaches for the design and study of fibril-forming peptides / Phanourios Tamamis ... [et al.] -- Posttranslational incorporation of noncanonical amino acids in the RNase S system by semisynthetic protein assembly / Maika Genz and Norbert Sträter -- Design, synthesis, and study of fluorinated proteins / Benjamin C. Buer and E. Neil G. Marsh -- High-quality combinatorial protein libraries using the binary patterning approach / Luke H. Bradley -- Methods for library-scale computational protein design / Lucas B. Johnson, Thaddaus R. Huber, and Christopher D. Snow -- Symmetric protein architecture in protein design : top-down symmetric deconstruction / Liam M. Longo and Michael Blaber -- Identification of protein scaffolds for enzyme design using scaffold selection / André C. Stiel, Kaspar Feldmeier, and Birte Höcker -- Computational design of novel enzymes without cofactors / Matthew D. Smith, Alexandre Zanghellini, and Daniela Grabs-Röthlisberger -- De novo design of peptide scaffolds as novel preorganized ligands for metal-ion coordination / Aimee J. Gamble and Anna F. A. Peacock -- Computational design of metalloproteins / Avanish S. Parmar, Douglas Pike, and Vikas Nanda -- Incorporation of modified and artificial cofactors into naturally occurring protein scaffolds / Koji Oohora and Takashi Hayashi -- Computational redesign of metalloenzymes for catalyzing new reactions / Per Jr. Greisen and Sagar D. Khare.
  • 2006 Springer Protocols
    edited by Raphael Guerois, Manuela López de la Paz.
    Design of structural elementary motifs. Structure and stability of the [alpha]-helix: lessons for design / Neil Errington, Teuku Iqbalsyah, and Andrew J. Doig. De novo design of monomeric [beta]-hairpin and [beta]-sheet peptides / David Pantoja-Uceda, Clara M. Santiveri, and M. Angeles Jiménez. De novo proteins from binary-patterned combinatorial libraries / Luke H. Bradley, Peter P. Thumfort, and Michael H. Hecht. Non-protein amino acids in the design of secondary structure scaffolds / Radhakrishnan Mahalakshmi and Padmanabhan Balaram. Design and synthesis of [beta]-peptides with biological activity / Marc J. Koyack and Richard P. Cheng -- Design of entire proteins and protein complexes. Design of miniproteins by the transfer of active sites onto small-size scaffolds / Franc̦ois Stricher, Loïc Martin, and Claudio Vita. Consensus design as a tool for engineering repeat proteins / Tommi Kajander, Aitziber L. Cortajarena, and Lynne Regan. Multiple sequence alignment as a guideline for protein engineering strategies / Alan R. Davidson. Sequence search methods and scoring functions for the design of protein structures / Hocine Madaoui, Emmanuelle Becker, and Raphael Guerois. Prediction of protein-protein interaction based on structure / Gregorio Fernandez-Ballester and Luis Serrano. Electrostatic design of protein-protein association rates / Gideon Schreiber, Yossi Shaul, and Kay E. Gottschalk -- Design of amyloidogenic polypeptides and amyloid inhibitors. Peptide model systems for amyloid fiber formation: design strategies and validation methods / Alexandra Esteras-Chopo, María Teresa Pastor, and Manuela López de la Paz. Protein misfolding disorders and rational design of antimisfolding agents / Lisbell D. Estrada, June Yowtak, and Claudio Soto.
  • 2012 Springer
    edited by Jacqueline M. Matthews.
    Also available: Print – 2012
  • 2014 Springer Protocols
    edited by Nikolaos E. Labrou.
    Protein Purification: An Overview -- Establishment of a Design Space for Biopharmaceutical Purification Processes Using DoE -- High Throughput Process Development: I. Process Chromatography -- High Throughput Process Development: II. Membrane Chromatography -- Media Selection in Ion Exchange Chromatography in a Single Microplate -- High Throughput Screening of Dye-Ligands for Chromatography -- Measurement of Uptake Curves and Adsorption Isotherms by Automated Microscale Chromatography Pipette Tips -- Recovery of Recombinant Proteins from Plants Using Aqueous Two-Phase Partitioning Systems: An Outline -- Aqueous Two-Phase Systems Strategies for the Recovery of Proteins from Plants -- Aqueous Two Phase Assisted Precipitation of Proteins: A Platform for Isolation of Process Related Impurities from Therapeutic Proteins -- Simultaneous Purification and Refolding of Proteins by Affinity Precipitation and Macro-(Affinity Ligand) Facilitated Three Phase Partitioning (MLFTPP) -- Co-Expression and Co-Purification of Antigen-Antibody Complexes in Bacterial Cytoplasm and Periplasm -- Immunoglobulin Purification by Caprylic Acid -- Affinity Tags in Protein Purification and Peptide Enrichment: An Overview -- Expression and Purification of Large Active GST Fusion Enzymes -- Synthetic Ligand Affinity Chromatography. Purification of Human Serum Albumin and Related Fusion Proteins -- Zbasic -- A Purification Tag for Selective Ion-Exchange Recovery -- An Orthogonal Fusion Tag for Efficient Protein Purification -- Phage Display of Engineered Binding Proteins -- Biomimetic Affinity Ligands for Protein Purification -- Synthesis and Application of Dye-Ligand Affinity Adsorbents -- Peptide Affinity Chromatography Based on Combinatorial Strategies for Protein Purification -- Affinity Chromatography of Proteins on Monolithic Columns -- Sample Displacement Batch Chromatography of Proteins -- Analysis of Host-Cell Proteins in Biotherapeutic Proteins by LC/MS Approaches -- Preparation of Monolithic Affinity Media for Nano-Liquid Chromatography Applications -- Proteomic Analysis of Complex Protein Samples by MALDI TOF Mass Spectrometry -- Modern Bioanalysis of Proteins by Electrophoretic Techniques -- Protein Structure Validation and Analysis with X-Ray Crystallography -- Measuring Binding Constants of His-Tagged Proteins using Affinity Chromatography and Ni-NTA Immobilized Enzymes -- Stabilization of Therapeutic Proteins in Aqueous Solutions and Freeze-Dried Solids: An Overview -- Stabilization of Protein by Freeze-Drying in the Presence of Trehalose: A Case Study of Tubulin -- G Protein-Coupled Receptor Expression and Purification.- (Hyper)thermophilic Enzymes: Production and Purification -- Affinity Chromatography for Antibody Purification -- Screening and Purification of Recombinant Lignocellulolytic Enzymes -- Purification of PEGylated Proteins, with the Example of PEGylated lysozyme and PEGylated scFv -- One-Step Purification of Glutamate decarboxylase from E. coli Using Aqueous Two Phase System.
  • 2014 Springer Protocols
    edited by Dennis R. Livesay.
    Monitoring Side-Chain Dynamics of Proteins Using 2H Relaxation -- CPMG Relaxation Dispersion -- Confocal Single-Molecule FRET for Protein Conformational Dynamics -- Protein Structural Dynamics Revealed by Site-directed Spin Labeling and Multifrequency EPR -- Probing Backbone Dynamics With Hydrogen/Deuterium Exchange Mass Spectrometry -- Carbon-Deuterium Bonds as Non-perturbative Infrared Probes of Protein Dynamics, Electrostatics, Heterogeneity, and Folding -- Balancing Bond, Nonbond and G?-like Terms in Coarse Grain Simulations of Conformational Dynamics -- Tutorial on Building Markov State Models with MSMBuilder and Coarse-graining them with BACE -- Analysis of Protein Conformational Transitions Using Elastic Network Model -- Geometric Simulation of Flexible Motion in Proteins -- Principal Component Analysis: A Method for Determining the Essential Dynamics of Proteins -- A Case Study Comparing Quantitative Stability/Flexibility Relationships Across Five Metallo-?-Lactamases Highlighting Differences within NDM-1 -- Towards Comprehensive Analysis of Protein Family Quantitative Stability/Flexibility Relationships using Homology Models -- Using the COREX/BEST Server to Model the Native State Ensemble -- Morphing Methods to Visualize Coarse-grained Protein Dynamics.
  • 2012 Springer Protocols
    edited by Biji T. Kurien and R. Hal Scofield.
    How it all began : a personal history of gel electrophoresis / Oliver Smithies -- Introduction to protein electrophoresis / Pothur R. Srinivas -- Protein quantification methods to determine protein concentration prior to electrophoresis / J.P. Dean Goldring -- Protein solubilization : attend to the choice of lysis buffer / Mandy Peach, Noelle Marsh, and Daniel J. MacPhee -- Native polyacrylamide gels / Claudia Arndt [and others] -- Cationic electrophoresis / Engelbert Buxbaum -- SARCOSYL-PAGE : a new electrophoretic method for the separation and immunological detection of PEGylated proteins / Christian Reichel -- Tricine-SDS-PAGE / Syed R. Haider, Helen J. Reid, and Barry L. Sharp -- Analysis of protein glycation using phenylboronate acrylamide gel electrophoresis / Marta P. Pereira Morais [and others] -- Protein electrophoresis in agarose gels for separating high molecular weight proteins / Marion L. Greaser and Chad M. Warren -- Increase in local protein concentration by field-inversion gel electrophoresis / Henghang Tsai and Hon-chiu Eastwood Leung -- Combined free flow electrophoresis and DIGE approach to compare proteins in complex biological samples / Kim Y.C. Fung [and others] -- Immunofixation electrophoresis for identification of proteins and specific antibodies / Gyorgy Csako -- Microchip electrophoresis, with respect to "Profiling of Abeta Peptides in the Cerebrospinal Fluid of Patients with Alzheimer's Disease" / Mohamad Reza Mohamadi [and others] -- Foodomics approach : CE-MS for comparative metabolomics of colon cancer cells treated with dietary polyphenols / Mustafa Celebier [and others] -- Peptide fractionation by SDS-free polyacrylamide gel electrophoresis for proteomic analysis via DF-PAGE / Yassel Ramos, Vladimir Besada, and Lila Castellanos-Serra -- Tris-acetate polyacrylamide gradient gels for the simultaneous electrophoretic analysis of proteins of very high and low molecular Mass / Monica Cubillos-Rojas [and others] -- SDS-PAGE for ³⁵S immunoprecipitation and immunoprecipitation western blotting / Edward P. Trieu and Ira N. Targoff -- Two-dimensional gel electrophoresis : vertical isoelectric focusing / Yaser Dorri -- Isoelectric focusing in agarose gel for detection of oligoclonal bands in cerebrospinal and other biological fluids / Gyorgy Csako -- Native flatbed isoelectric focusing for determining antibody clonotype distribution / Biji T. Kurien and R. Hal Scofield -- Two-dimensional gel electrophoresis : glass tube-based IEF followed by SDS-PAGE / Hiroyuki Matsumoto [and others] -- One-dimensional and two-dimensional immobilized metal affinity electrophoresis / Bao-Shiang Lee [and others] -- Two-dimensional difference gel electrophoresis / Jonathan S. Minden -- Protein identification on archived 2-D dels / Hiroyuki Matsumoto, Nobuaki Takemori, and Naoka Komori -- Diagonal Electrophoresis for the Detection of Protein Disulfides / Brian McDonagh -- Two-dimensional blue native/SDS gel electrophoresis of multiprotein complexes / Jean Paul Lasserre and Armelle Menard -- Immunoelectrophoresis : a method with many faces / Gyorgy Csako -- Cell surface protein biotinylation for SDS-PAGE analysis / Giuliano Elia -- Multichannel gel electrophoresis and continuous fraction collection apparatus for high-throughput protein separation and characterization / Ming Dong [and others] -- Gel-absorption-based sample preparation method for shotgun analysis of membrane proteome / Xianchun Wang and Songping Liang -- Interactions of hemoglobin in live red blood cells measured by the electrophoresis release test / Yan Su, Lijun Gao, and Wenbin Qin -- Extraction of proteins from gels : a brief review / Biji T. Kurien and R. Hal Scofield -- New algorithm for the simulation of SDS 2D-PAGE datasets / Emilio Marengo and Elisa Robotti -- Isolation of proteins from polyacrylamide gels / Irene Michalk [and others] -- Gel drying methods / Slava Stamova [and others] -- Long-term, buffer-less, wet gel storage in non-sealed polyethylene bags / Biji T. Kurien and R. Hal Scofield -- Brief review of other notable electrophoretic methods / James D. Fesmire -- Protein stains and applications / Ranjini K. Sundaram, Natarajan Balasubramaniyan -- Coomassie-brilliant blue staining of polyacrylamide gels / Claudia Arndt [and others] -- Accelerated coomassie blue staining and destaining of SDS-PAGE gels with application of heat / Biji T. Kurien and R. Hal Scofield -- Silver staining techniques of polyacrylamide gels / Holger Bartsch [and others] -- Revisit of imidazole-zinc reverse stain for protein polyacrylamide gel electrophoresis / Han-Min Chen -- Counterion dye staining of proteins in one- and two-dimensional sodium dodecyl sulfate-polyacrylamide gel electrophoresis and tryptic gel digestion of stained protein for mass spectrometry / Wei-Tao Cong [and others] -- TEMED-enhanced photoluminescent imaging of human serum proteins by quantum dots after PAGE / Na Na and Jin Ouyang -- Microwave-assisted protein staining, destaining, and in-gel/in-solution digestion of proteins / Jennie R. Lill and Victor J. Nesatyy -- Electrophoretic separation and detection of metalloproteins by x-ray fluorescence mapping / Tripti Khare, Yasmin Chishti, and Lydia A. Finney -- Fluorescent staining of gels / Engelbert Buxbaum -- Single-step simultaneous protein staining procedure for polyacrylamide gels and nitrocellulose membranes by alta during western blot analysis / Jayanta K. Pal, Sunil K. Berwal, and Rupali N. Soni -- Detection of glycoproteins in polyacrylamide gels using Pro-Q Emerald 300 dye, a fluorescent periodate schiff-base stain / Padmaja Mehta-D'souza -- Spicy SDS-PAGE gels : curcumin/turmeric as an environment-friendly protein stain / Biji T. Kurien, Yaser Dorri, and R. Hal Scofield -- In-gel staining of proteins in native polyacrylamide gel electrophoresis using meso-tetrakis(4-sulfonatophenyl) porphyrin / K. Divakar, G. Nandhini Devi, and Pennathur Gautam -- Rapid detection of proteins in polyacrylamide electrophoresis gels with direct red 81 and amido black / David Choveaux, Robert G.E. Krause, and J.P. Dean Goldring -- Zymographic assay of oxidases using peroxidase or hemin entrapped in polyacrylamide gel / Mircea Alexandru Mateescu [and others] -- Coomassie brilliant blue removal/disposal from gel destain and used gel stain in an environment-friendly manner / Biji T. Kurien and Yaser Dorri -- Brief review of other notable protein detection methods on acrylamide gels / Biji T. Kurien and R. Hal Scofield -- Ultrasensitive protein detection and imaging : comparison of lumitein, proteoSilver, SYPRO® Ruby, and Coomassie® Brilliant Blue Gel stains / Guang Ren, Carl K. Okerberg, and Suresh T. Mathews -- Common artifacts and mistakes made in electrophoresis / Biji T. Kurien and R. Hal Scofield.
  • 2012
    Debanti Sengupta.
    There is a tremendous need for muscle regeneration therapies to replace tissue that is lost due to disease or injury. This work is focused on developing engineered replacement therapies for lost or damaged skeletal and cardiovascular muscle tissue. In order to create viable, clinically relevant regenerative therapies, I have used recombinant protein technology to synthesize a family of protein-engineered biomaterials that incorporate critical cues for the recapitulation of in vivo muscle tissue conditions. Crucially, these biomaterials allow the independent tuning of multiple biomaterial properties including cell adhesivity, biomaterial stiffness, and topographical cues. Each of these biomaterial properties impacts muscle cell behavior independently as well as in concert. I have exploited the range of biomaterial tunability available to us to identify biomaterial conditions that enable production of striated muscle tissue using primary human skeletal muscle myoblasts (hMBs) that may be electrically paced. I have further demonstrated that mouse model skeletal muscle cell lines do not accurately recapitulate primary human myoblast behavior in response to biomaterial properties, particularly with respect to integrin-matrix interactions. Importantly, the expression of mature muscle markers that indicate muscle cell differentiation could be accelerated simply by changing biomaterial stiffness and introducing biomaterial microtopography. Finally, as demonstration that this protein-engineered biomaterial strategy may have application in the regeneration of myocardial as well as skeletal muscle tissue, cardiomyocytes derived from human embryonic stem cells exhibited good cell viability and improved contractility on these biomaterials. This thesis represents important advancements in the development of regenerative muscle tissue engineered constructs.
  • 2009 Springer
    Caroline Köhrer, Uttam L. RajBhandary (eds.).
    Understanding enzyme mechanism through protein chimeragenesis / N.M. Goodey and S.J. Benkovic -- Chemical protein engineering : synthetic and semisynthetic peptides and proteins / L. Merkel, L. Moroder, and N. Budisa -- Native chemical ligation: Semisynthesis of post-translationally modified proteins and biological probes / E. Vogel Taylor and B. Imperiali -- Chemical methods for mimicking post-translational modifications / S.I. van Kasteren, P. Garnier and B.G. Davis -- Noncanonical amino acids in protein science and engineering / K.E. Beatty and D.A. Tirrell -- Fidelity mechanisms of the aminoacyl-tRNA synthetases / A.P. Mascarenhas ... [et al.] -- Specialized components of the translational machinery for unnatural amino acid mutagenesis : tRNAs, aminoacyl-tRNA synthetases, and ribosomes / C. Köhrer and U.L. RajBhandary -- In vivo studies of receptors and ion channels with unnatural amino acids / D.A. Dougherty -- Synthesis of modified proteins using misacylated tRNAs / S.M. Hecht -- Cell-free synthesis of proteins with unnatural amino acids. The pure system and expansion of the genetic code / I. Hirao, T. Kanamori and T. Ueda -- Engineering nucleobases and polymerases for an expanded genetic alphabet / A.M. Leconte and F.E. Romesberg -- Understanding membrane proteins. How to design inhibitors of transmembrane protein-protein interactions / J.S. Slusky, H. Yin and W.F. DeGrado.
  • 2010 CRCnetBASE
    edited by Sheldon J. Park, Jennifer R. Cochran.
    "Experimental protein engineering and computational protein design are broad but complementary strategies for developing proteins with altered or novel structural properties and biological functions. By describing cutting-edge advances in both of these fields, Protein Engineering and Design aims to cultivate a synergistic approach to protein science. The first half of the book discusses experimental approaches to protein engineering and starts by describing several high-throughput screening platforms for protein engineering. Key techniques used for diversity generation are also discussed. The next few chapters present examples of therapeutics, enzymes, biomaterials, and other proteins that have been engineered by rational or combinatorial approaches. The section finishes with a chapter on the use of non-natural amino acids in protein engineering. The second half of the book introduces computational protein design, beginning with a chapter on computational and informatics algorithms used in protein engineering. Core components of computational protein design are then discussed in detail, and examples of heuristic protein design are provided. Subsequent chapters present examples of how computational design has played a critical role in advancing the field of protein engineering. Concluding with a chapter outlining current challenges in the field, this book makes computational protein design and diversity-oriented protein engineering widely accessible to a broad audience in academia and industry alike."--Publisher's description.
  • pt. A-B, 2012. ScienceDirect
    pt. B ScienceDirect
    edited by K. Dane Wittrup, Gregory L. Verdine.
  • 2006 Springer Protocols
    edited by Katja M. Arndt, Kristian M. Müller.
  • 2012 Springer Protocols
    edited by James L. Hartley.
    Why proteins in mammalian cells? / James L. Hartley -- Large-scale transfection of mammalian cells / Lucia Baldi [and others] -- Selection of high expressing mammalian cells by surface display of reporters / Christine T. DeMaria -- Expression of secreted protein in mammalian cells using baculovirus particles / Barbara Ann Jardin, Cynthia B. Elias, and Satya Prakash -- Transfection of difficult-to-transfect primary mammalian cells / Oliver Gresch and Ludger Altrogge -- Stable protein expression in mammalian cells using baculoviruses / Andreas Lackner [and others] -- Using matrix attachment regions to improve recombinant protein production / Niamh Harraghy [and others] -- Controlling apoptosis to optimize yields of prtoeins from mammalian cells / Matthew P. Zustiak [and others] -- Post-transcriptional regulatory elements for enhancing transient gene expression levels in mammalian cells / Mariati [and others] -- Converting monoclonal antibodies into Fab fragments for transient expression in mammalian cells / Joanne E. Nettleship [and others] -- Generation of high-expressing cells by methotrexate amplification of destabilized dihydrofolate reductase selection marker / Say Kong Ng -- Tools for coproducing multiple proteins in mammalian cells / Zahra Assur, Wayne A. Hendrickson, and Filippo Mancia -- Identification and characterization of protein glycosylation using specific endo- and exoglycosidases / Paula Magnelli, Alicia Bielik, and Ellen Guthrie -- Strategies for efficient transfection of CHO-cells with plasmid DNA / Renate Kunert and Karola Vorauer-Uhl -- Methods for constructing clones for protein expression in mammalian cells / Takefumi Sone and Fumio Imamoto -- Optimizing transient recombinant protein expression in mammalian cells / Ralph F. Hopkins, Vanessa E. Wall, and Dominic Esposito.
  • 2006 Springer
    Bengt Nölting.
    Introduction -- Structure of proteins -- Physical interactions that determine the properties of proteins -- Calculation of the kinetic rate constants -- High kinetic resolution of protein folding events -- Kinetic methods for slow reactions -- Resolution of protein structures in solution -- High structural resolution of transient protein conformations -- Experimental problems of the kinetic and structural resolution of reactions that involve proteins -- The folding pathway of protein (barstar) at the resolution of individual residues from microseconds to seconds -- Highly resolved folding pathways and mechanisms of six proteins -- Structural determinants of the rate of protein folding -- Evolutionary computer programming of protein structure and folding.
  • 2011 Springer Protocols
    edited by Andrew F. Hill, Kevin J. Barnham, Stephen P. Bottomley, Roberto Cappai.
    Strategies for boosting the accumulation of correctly folded recombinant proteins expressed in Escherichia coli / Ario de Marco -- Escherichia coli cell-free system for recombinant protein synthesis on a milligram scale / Luke A. Miles [and others] -- Synthesis of peptide sequences derived from fibril-forming proteins / Denis B. Scanlon and John A. Karas -- Refolding your protein with a little help from REFOLD / Jennifer Phan [and others] -- Circular dichroism and its use in protein-folding studies / David T. Clarke -- Distance measurements by continuous wave EPR spectroscopy to monitor protein folding / James A. Cooke and Louise J. Brown -- Solution-state nuclear magnetic resonance spectroscopy and protein folding / Lisa D. Cabrita [and others] -- Diagnostics for amyloid fibril formation : where to begin / Danny M. Hatters and Michael D.W. Griffin -- Probing protein aggregation with quartz crystal microbalances / Tuomas P.J. Knowles [and others] -- Dried and hydrated x-ray scattering analysis of amyloid fibrils / Sally L. Gras and Adam M. Squires -- Solid-state NMR of amyloid membrane interactions / John D. Gehman and Frances Separovic -- Sedimentation velocity analysis of amyloid fibrils / Chi Le Lan Pham, Yee-Foong Mok, and Geoffrey J. Howlett -- Transmission electron microscopy of amyloid fibrils / Sally L. Gras, Lynne J. Waddington, and Kenneth N. Goldie -- Surface plasmon resonance spectroscopy : a new lead in studying the membrane binding of amyloidogenic transthyretin / Xu Hou, David H. Small, and Marie-Isabel Aguilar -- Elucidating the role of metals in Alzheimer's disease through the use of surface-enhanced laser desorption/ionisation time-of-flight mass spectrometry / Andrew D. Watt, Keyla A. Perez, and Lin Wai Hung.
  • 2006 Springer Protocols
    edited by Yawen Bai and Ruth Nussinov.
  • 2016 Karger
    editors, Jatinder Bhatia, Raanan Shamir, Yvan Vandenplas.
    Proteins, peptides and amino acids : role in infant nutrition / Nutten, S. -- Hydrolyzed proteins in allergy / Salvatore, S.; Vandenplas, Y. -- Infant formula with partially hydrolyzed proteins in functional gastrointestinal disorders / Vandenplas, Y.; Salvatore, S. -- Hydrolyzed proteins in preterm infants / Senterrre, T.; Rigo, J. -- Hydrolyzed formula for every infant? / Fleischer, D.M.; Venter, C.; Vandenplas, Y. -- The benefits of breast feeding / Shamir, R. -- Protein evolution of human milk / Thakkar, S.K.; Giuffrida, F.; Bertschy, E.; De Castro, A.; Destaillats, F.; Lee, L.Y. -- Metabolic programming : effects of early nutrition on growth, metabolism and body composition / Haschke, F.; Grathwohl, D. Haiden, N. -- Human milk : bioactive proteins/peptides and functional properties / Lönnerdal, B.L. -- Human milk for preterm infants and fortification / Bhatia, J. -- Protein needs of preterm infants : why are they so difficult to meet? / Ziegler, E.E. -- Optimizing early protein intake for long-term health of preterm infants / Singhal, A. -- Defining protein requirements of preterm infants by using metabolic studies in fetuses and preterm infants / van den Akker, C.H.P.; van Goudoever, J.B. -- Amino acid intake in preterm infants / Burattini, I.; Bellagamba, M.P.; D'Ascenzo, R.; Biagetti, C.; Carnielli, V.P.
  • 2007 Springer
    edited by Peter Schuck.
  • 2010 Springer
    Marcelo G. Kazanietz, editor.
    Protein kinase C in cancer signaling and therapy: introduction and historical perspective -- Regulation of conventional and novel protein kinase C isozymes by phosphorylation and lipids -- Phorbol esters and diacylglycerol: the PKC activators -- Diacylglycerol signaling: the C1 domain, generation of DAG and termination of signals -- Regulation of PKC by protein-protein interaction in cancer -- Introduction: PKC isozymes in the control of cell function -- Regulation and function of protein kinase C signaling -- PKC and control of the cell cycle -- PKC and the control of apoptosis -- Atypical PKC's, NF-kB and inflammation -- Introduction: PKC and cancer -- Protein kinase C, p53, and DNA damage -- PKCs as mediators of the hedgehog and Wnt signaling pathways -- PKC-PKD interplay in cancer -- Transgenic mouse models to investigate functional specificity of protein kinase C isoforms in the development of squamous cell carcinoma, a nonmelanoma human skin cancer -- PKC isozymes and skin cancer -- PKC and breast cancer -- PKC and prostate cancer -- Protein kinase C and lung cancer -- Introduction [PKC isozymes as targets for cancer therapy] -- PKC and resistance to chemotherapeutic agents -- PKCd as a target for chemotherapeutic drugs -- Atypical PKCs as targets for cancer therapy.
  • 2015 Springer
    Khalil Ahmed, Olaf-Georg Issinger, Ryszard Szyszka, editors
  • 2014 ScienceDirect
    volume editor, Kevan M. Shokat.
    Catalytic mechanisms and regulation of protein kinases / Zhihong Wang and Philip A. Cole -- A structural atlas of kinases inhibited by clinically approved drugs / Qi Wang, Julie A. Zorn, and John Kuriyan -- Fragment-based approaches to the discovery of kinase inhibitors / Paul N. Mortenson, Valerio Berdini, and Marc O'Reilly -- Targeting protein kinases with selective and semi-promiscuous covalent inhibitors / Rand M. Miller and Jack Taunton -- The resistance tetrad: amino acid hotspots for kinome-wide exploitation of drug-resistant protein kinase alleles / Fiona P. Bailey, Veselin I. Andreev, and Patrick A. Eyers -- FLiK: a direct binding assay for the identification and kinetic characterization of stabilizers of inactive kinase conformations / Jeffrey R. Simar and Daniel Rauh -- Discovery of allosteric BCR-ABL inhibitors from phenotypic screen to clinical candidate / Nathanael S. Gray and Doriano Fabbro -- The logic and design of analog-sensitive kinases and their small molecule inhibitors / Michael S. Lopez, Joseph I. Kliegman, and Kevan M. Shokat.
  • 2012 Springer Protocols
    edited by Hideyuki Mukai.
    Visualization of protein kinase activities in living cells / Kazuhiro Aoki, Naoki Komatsu, Akihiro Goto, and Michiyuki Matsuda -- Phos-tag affinity electrophoresis for protein kinase profiling / Eiji Kinoshita, Emiko Kinoshita-Kikuta, and Tohru Koike -- Large-scale protein phosphorylation analysis by mass spectrometry-based phosphoproteomics / Wei-Chi Ku, Naoyuki Sugiyama, and Yasushi Ishihama -- Ca2+/calmodulin-dependent protein kinase II (CaMKII) / Steven J. Coultrap and K. Ulrich Bayer -- CASK : a specialized neuronal kinase / Konark Mukherjee -- Cyclin-dependent kinase 5 (Cdk5) : preparation and measurement of kinase activity / Seiji Minegishi, Taro Saito, and Shin-ichi Hisanaga -- ErbB membrane tyrosine kinase receptors : analyzing migration in a highly complex signaling system / Nicole M. Brossier, Stephanie J. Byer, Lafe T. Peavler, and Steven L. Carroll -- Extracellular signal-regulated kinase (ERK) cascade in neuronal cell signaling / Daniel Orellana, Ilaria Morella, Marzia Indrigo, Alessandro Papale, and Riccardo Brambilla -- Glycogen synthase kinase-3 in neurological diseases / Oksana Kaidanovich-Beilin and James Robert Woodgett -- Cortical neurons culture to study c-Jun N-terminal kinase signaling pathway / Alessandra Sclip, Xanthi Antoniou, and Tiziana Borsello -- MuSK : a kinase critical for the formation and maintenance of the neuromuscular junction / Arnab Barik, Wen-cheng Xiong, and Lin Mei -- Assays for pten-induced novel kinase 1 (PINK1) and leucine-rich repeat kinase 2 (LRRK2), kinases associated with parkinson's disease / Alexandra Beilina and Mark R. Cookson -- Imaging PKA activation inside neurons in brain slice preparations / Marina Brito, Elvire Guiot, and Pierre Vincent -- Imaging oscillations of protein kinase C activity in cells / Maya T. Kunkel and Alexandra C. Newton -- Diacylglycerol kinase (DGK) as a regulator of PKC / Yasuhito Shirai and Naoaki Saito -- Trafficking of Trk receptors / Daniel Bodmer and Rejji Kuruvilla -- Mammalian target of rapamycin / Lukasz J. Swiech, Malgorzata Urbanska, Matylda Macias, Agnieszka Skalecka, and Jacek Jaworski -- Protein kinase G (PKG) : involvement in promoting neural cell survival, proliferation, synaptogenesis, and synaptic plasticity and the use of new ultrasensitive capillary-electrophoresis-based methodologies for measuring PKG expression and molecular actions / Ronald R. Fiscus and Mary G. Johlfs -- Electrophysiological technique for analysis of synaptic function of PKN1 in hippocampus / Hiroki Yasuda and Hideyuki Mukai.
  • 2010 Springer
    edited by Nektarios Tavernarakis.
    Synthesis, modification, and turnover of proteins during aging / Suresh I.S. Rattan -- Regulation of mRNA translation as a conserved mechanism of longevity control / Ranjana Mehta ... [et al.] -- Protein synthesis and the antagonistic pleiotropy hypothesis of aging / Pankaj Kapahi -- Proteasome function determines cellular homeostasis and the rate of aging / Niki Chondrogianni and Efstathios S. Gonos -- Autophagy and longevity : lessons from C. elegans / Kailiang Jia and Beth Levine -- Autophagy and aging : lessons from progeria models / Guillermo Mario, Alvaro F. Fernandez and Carlos Lopez-Oton -- Regulation of protein turnover by longevity pathways / Tibor Vellai and Krisztina Takocs-Vellai -- Protein metabolism and lifespan in Caenorhabditis elegans / Geert Depuydt, Jacques R. Vanfleteren, and Bart P. Braeckman -- Mitochondrial protein quality control systems in aging and disease / Karin Luce, Andrea C. Weil, and Heinz D. Osiewacz -- p38MAPK in the senescence of human and murine fibroblasts / Florence Debacq-Chainiaux ... [et al.] -- Protein homeostasis in models of aging and age related conformational disease / Elise A. Kikis, Tali Gidalevitz, and Richard I. Morimoto -- Roles for SUMO modification during senescence / Artemisia M. Andreou and Nektarios Tavernarakis -- Post-translational modification of cellular proteins by ubiquitin and ubiquitin-like molecules : role in cellular senescence and aging / Johannes Grillari, Regina Grillari-Voglauer, and Pidder Jansen-Dorr -- Sensory influence on homeostasis and lifespan : molecules and circuits / Joy Alcedo, Wolfgang Maier, and Queelim Ch'ng -- Regulation of muscle atrophy in aging and disease / Manlio Vinciguerra, Antonio Musaro, and Nadia Rosenthal -- Confronting cellular heterogeneity in studies of protein metabolism and homeostasis in aging research / Louise Boisen and Peter Kristensen.
    Also available: Print – 2010
  • 2011 Springer Protocols
    edited by Catherine J. Wu.
    [Publisher-supplied data] Protein microarrays have been used for a wide variety of important tasks, such as identifying protein-protein interactions, discovering disease biomarkers, identifying DNA-binding specificity by protein variants, and for characterization of the humoral immune response. In Protein Microarray for Disease Analysis: Methods and Protocols, expert researchers provide concise descriptions of the methodologies currently used to fabricate microarrays for the comprehensive analysis of proteins or responses to proteins that can be used to dissect human disease. These methodologies are the toolbox for revolutionizing drug development and cell-level biochemical understanding of human disease processes. Beginning with a section on protein-detecting analytical microarrays, the volume continues with sections covering antigen microarrays for immunoprofiling, protein function microarrays, the validation of candidate targets, proteomic libraries, as well as signal detection strategies and data analysis techniques. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Practical and cutting-edge, Protein Microarray for Disease Analysis: Methods and Protocols serves as a solid framework to aid scientists in understanding how protein microarray technology is presently developing and how it can be applied to transform our analysis of human disease.
  • 2006
    Steven Man Cheong Chan.
    Status: Not Checked OutLane Catalog Record
  • 2011 Springer Protocols
    edited by Ulrike Korf.
    Reverse phase protein microarrays for clinical applications -- Impact of blocking and detection chemistries on antibody performance for reverse phase protein arrays -- Phosphoprotein stability in clinical tissue and its relevance for reverse phase protein microarray technology -- Utilization of RNAi to validate antibodies for reverse phase protein arrays -- Antibody-mediated signal amplification for reverse phase protein array-based protein quantification -- Reverse-phase protein lysate microarray (RPA) for the experimental validation of quantitative protein network models -- Characterization of kinase inhibitors using reverse phase protein arrays -- Use of formalin-fixed and paraffin-embedded tissues for diagnosis and therapy in routine clinical settings -- Producing reverse phase protein microarrays from formalin-fixed tissues -- Use of reverse phase protein microarrays to study protein expression in leukemia: Technical and methodological lessons learned -- Antibody microarrays as tools for biomarker discovery -- Assessment of antibody specificity using suspension bead arrays -- Quantitative analysis of phosphoproteins using microspot immunoassays -- Robust protein profiling with complex antibody microarrays in a dual-colour mode -- High-throughput studies of protein glycoforms using antibody-lectin sandwich arrays -- Microspot immunoassay-based analysis of plasma protein profiles for biomarker discovery strategies -- Recombinant antibodies for the generation of antibody arrays -- Producing protein microarrays from DNA microarrays -- Cell arrays and high-content screening -- Probing calmodulin protein-protein interactions using high-content protein arrays -- Protein function microarrays for customised systems-oriented proteome analysis -- Optimized autoantibody profiling on protein arrays -- Inkjet printing for the production of protein microarrays -- Impact of substrates for probe immobilization -- Contact printing of protein microarrays.
  • 2006 Springer
    edited by Vladimir N. Uversky, Anthony L. Fink.
  • 2007 Springer
    edited by Vladimir N. Uversky, Anthony L. Fink.
  • 2010 Springer Protocols
    edited by Peter Bross and Niels Gregersen.
    Protein misfolding and celluar stress : an overview / Niels Gregersen and Peter Bross -- Protein aggregation diseases : toxicity of soluble prefibrillar aggregates and their clinical significance / Massimo Stefani -- Consequences of stress in the secretary pathway : the ER stress response and its role in the metabolic syndrome / Martin Schröder and Louise Sutcliffe -- What role does mitochondrial stress play in neurodegenerative diseases? / Alicia Mae Pickrell and Carlos Torres Moraes -- Autophagy in disease / Dalibor Mijaljica, Mark Prescott, and Rodney J. Devenish -- Mitophagy and mitoptosis in disease processes / Dalibor Mijaljica, Mark Prescott, and Rodney J. Devenish -- Cellular stress and protein misfolding during aging / Rajiv Vaid Basaiawmoit and Suresh I.S. Rattan -- Measuring consequences of protein misfolding and cellular stress using OMICS techniques / Peter Bross ... [et al.] -- Production of cells with targeted integration of gene variants of human ABC transporter for stable and regulated expression using the Flp recombinase system / Kanako Wakabayashi-Nakao ... [et al.] -- Stress response profile in human fribroblasts exposed to heat shock or oxidative stress / Christina Bak Pedersen and Niels Gregersen -- Examining ubiquitinated protein aggregates in tissue sections / Natalia A. Kaniuk and John H. Brumell -- Determination of proteasomal activities / Cristovao F. Lima and Suresh I.S. Rattan -- Measurement of autophagy in cells and tissues / Isei Tanida and Satoshi Waguri -- Transcription factor sequestration by polyglutamine proteins / Tomoyuki Yamanaka and Nobuyuki Nukina -- Biological membranes as protein aggregation matrices and targets of amyloid toxicity / Monica Bucciantini and Cristina Cecchi -- Measurement of mitochondrial ROS production / Anatoly A. Starkov -- In vivo detection of oxidized proteins : a practical approach to tissue-derived mitochondria / Francesca Maltecca and Giorgio Casari -- Measurement of oxidized/reduced glutathione ratio / Joshua B. Owen and D. Allan Butterfield -- Determination of altered mitochondria ultrastructure by electron microscopy / Shoichi Sasaki -- Assessing bad sub-cellular localization under conditions associated with prevention or promotion of mitochondrial permeability transition-dependent toxicity / Liana Cerioni and Orazio Cantoni -- A cellular viability assay to monitor drug toxicity / Jakob Hansen and Peter Bross -- Rescue of misfolded proteins and stabilization by small molecules / Raymond C. Stevens, javier Sancho, and Aurora Martinez.
  • 2008 CRCnetBASE
    edited by H. John Smith, Claire Simons, Robert D.E. Sewell.
    Protein folding and misfolding, relevance to disease, and biological function / Massimo Stefani -- Alzheimer's disease / Charlotte E. Teunissen and Tischa J.M. van der Cammen -- Improving cholinergic transmission -- Cholinergic transmission and acetylcholine release enhancers / Pierre Francotte, Pascal de Tullio, and Bernard Pirotte -- AChE and its inhibition / Jure Stojan -- AChE inhibitors and their clinical assessment / Pierre Francotte, Pascal de Tullio, and Bernard Pirotte -- Reduction in plaque formation -- Secretase and APP processing / Christian Czech, Helmut Jacobsen, and Celine Adessi -- Mechanism of plaque formation and A[B] aggregation inhibitors / Christian Czech, Helmut Jacobsen, and Celine Adessi -- Nonsteroidal anti-inflammatory drugs / Bruno P. Imbimbo and Francesca Speroni -- 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors / Dario Cattaneo -- A[B] polymerization reduction / Harry LeVine III and Corrine E. Augelli-Szafran -- Carbonic anhydrase activators as potential anti-Alzheimer's disease agents / Claudiu T. Supuran and Andrea Scozzafava -- Detection and reduction of neurofibrillary lesions / Jeff Kuret -- Protein misfolding in Alzheimer disease : pathogenic or protective? / Rudy J. Castellani ... [et al.] -- Enhancement of brain retinoic acid levels / Ann B. Goodman ... [et al.] -- Parkinson's disease : what is it? what causes it? and how can it be cured? / Tom Foltynie, Andrew W. Michell, and Roger A. Barker -- Restoring dopamine levels / P. Nuno Palma .. [et al.] -- Huntington's disease / Claire-Anne Gutekunst and Fran Norflus -- Amyotrophic lateral sclerosis (motor neuron disease) / Teresa Sanelli ... [et al.] -- Transmissible spongiform encephalopathies / Michael D. Geschwind and Giuseppe Legname -- Overview / H. John Smith, Robert D.E. Sewell, and Claire Simons.
  • 2005 Springer
    [edited by] Jerry Eichler.
    Protein translocation across the endoplasmic reticulum membrane / Ramanujan S. Hegde -- Preprotein translocation through the sec translocon in bacteria / Antoine P. Maillard, Kenneth K.Y. Chan, and Franck Duong -- Protein translocation in archaea / Jerry Eichler -- Structure of the SecYEG protein translocation complex / Ian Collinson -- Membrane protein insertion in bacteria from a structural perspective / Mark Paetzel and Ross E. Dalbey -- The twin-arginine transport system / Frank Sargent, Ben C. Berks, and Tracy Palmer -- Retro-translocation of proteins across the endoplasmic reticulum membrane / J. Michael Lord and Lynne M. Roberts -- Chloroplast protein targeting: multiple pathways for a complex organelle / Matthew D. Smith and Danny J. Schnell -- The mitochondrial protein import machinery / Doron Rapaport -- Import of proteins into peroxisomes / Sven Thoms and Ralf Erdmann.
  • 2013 Springer Protocols
    edited by Juliet A. Gerrard.
    Protein nanotechnology: What is it? -- Bioengineered silk proteins to control cell and tissue functions -- Aqueous-based spinning of fibers from self-assembling structural proteins -- Fibrous protein nanofibers -- Self-assembling nanomaterials: Monitoring the formation of amyloid fibrils, with a focus on small-angle x-ray scattering -- Amyloid fibrils from readily available sources: Milk casein and lens crystallin proteins -- Formation of amphipathic amyloid monolayers from fungal hydrophobin proteins -- Proteins and peptides as biological nanowires: Towards biosensing devices -- Nanotechnology with s-layer proteins -- Stimuli-responsive peptide nanostructures at the fluid-fluid interface -- Designed self-assembling peptides as templates for the synthesis of metal nanoparticles -- Purification of molecular machines and nanomotors using phage-derived monoclonal antibody fragments -- Determination of enzyme thermal parameters for rational enzyme engineering and environmental/evolutionary studies -- Rational-based protein engineering: Tips and tools -- Construction and analysis of randomized protein-encoding libraries using error-prone PCR -- Droplets as reaction compartments for protein nanotechnology -- Label-free, real-time interaction and adsorption analysis 1: Surface plasmon resonance -- Label-free, real-time interaction and adsorption analysis 2: Quartz crystal microbalance -- Atomic force microscopy for protein nanotechnology.
  • 2012 Springer Protocols
    edited by Alexander Shekhtman and David S. Burz.
    A novel bacterial expression method with optimized parameters for very high yield production of triple-labeled proteins -- Isotopic labeling of heterologous proteins in the yeast Pichia pastoris and kluyveromyces lactis -- Isotope labeling in insect cells -- Isotope labeling in mammalian cells -- Cell-free protein production for NMR studies -- Cell-free membrane protein expression for solid-state NMR -- Expression and purification of Src-family kinases for solution NMR studies -- NMR studies of large protein systems -- Protein dynamics by (15)n nuclear magnetic relaxation -- Bacterial production and solution NMR studies of a viral membrane ion channel -- Preparation of the modular multi-domain protein RPA for study by NMR spectroscopy -- NMR studies of protein-RNA interactions -- Preparation and optimization of protein-DNA complexes suitable for detailed NMR studies -- NMR studies of protein-ligand interactions -- In-cell NMR spectroscopy in escherichia coli -- Deuterated peptides and proteins: Structure and dynamics studies by MAS solid-state NMR -- Solid-state NMR spectroscopy of protein complexes -- Synthesis, purification, and characterization of single helix membrane peptides and proteins for NMR spectroscopy -- Assignment of backbone resonances in a eukaryotic protein kinase -- ERK2 as a representative example -- Electrostatics of hydrogen exchange for analyzing protein flexibility -- Fast protein backbone NMR resonance assignment using the batch strategy -- Comprehensive automation for NMR structure determination of proteins -- Aria for solution and solid-state NMR -- Determining protein dynamics from (15)n relaxation data by using dynamics.
  • 2006 Springer Protocols
    edited by Greg Moorhead.
    Analysis of protein phosphatases / Shirish Shenolikar -- A brief introduction to the protein phosphatase families / Tomas Mustelin -- Small molecule inhibitors of Ser/thr protein phosphatases / Mark Swingle, Li Ni, and Richard E. Honkanen -- Synthesis and use of the protein phosphatase affinity matrices microcystin- and microcystin-biotin-sepharose / Greg Moorhead, Timothy A.J. Haystead, and Carol MacKintosh -- Utilizing protein phosphatase inhibitors to define PP2A as a regulator of ataxia-telangiectasia mutated (ATM) / Aaron A. Goodarzi ... [et al.] -- An automated, fluorescence-based method for continuous assay of PP2A activity / Adam M. Wegner ... [et al.] -- An in vivo assay to quantify stable protein phosphatase 2A (PP2A) heterotrimeric species / Matthew S. Gentry, Richard L. Hallberg, and David C. Pallas -- Mutagenesis and expression of the scaffolding Aa and Ab subunits of PP2A / Ralf Ruediger, Jin Zhou, and Gernot Walter -- Isolation and characterization of PP2A holoenzymes containing FLAG-tagged B subunits / Deanna G. Adams and Brian E. Wadzinski -- Purification of PP2A holoenzymes by sequential immunoprecipitation with anti-peptide antibodies / Gernot Walter, Jin Zhou, and Ralf Ruediger -- Purification of PP2Ac from bovine heart / Hue T. Tran ... [et al.] -- Visualization of intracellular PP1 targeting through transiently and stably expressed fluorescent protein fusions / Laura Trinkle-Mulcahy ... [et al.] -- Yeast two-hybrid screens to identify drosophila PP1-binding proteins / Daimark Bennett and Luke Alphey -- Identification of cellular protein phosphatase-1 regulators / David W. Roadcap, Matthew H. Brush, and Shirish Shenolikar -- Assay for 3-way interaction of protein phosphatase-1 (Glc7) with regulatory subunits plus phosphatase inhibitor-2 / Masumi Eto and David L. Brautigan -- Phosphorylation of the protein phosphatase type 1 inhibitor protein, CPI-17, by protein kinase C / Michael P. Walsh ... [et al.] -- Purification of smooth muscle myosin phosphatase using a thiophosphorylated myosin light chain-affinity resin / Merideth Borman and Justin MacDonald -- Proteins interacting with saccharomyces cerevisiae type 1 protein phosphatase catalytic subunit identified by single-step affinity purification and mass spectrometry / Edmund P. Walsh ... [et al.] -- Expression of protein histidine phosphatase in Escherichia coli, purification, and determination of enzyme activity / Nicole Bäumer .. [et al.] -- The use of RNA interference to analyze protein phosphatase function in mammalian cells / Iain Fraser ... [et al.] -- Recognition of a PP2C interaction motif in several plant protein kinases / Niranjan Chakraborty, Ohta Masaru, and Jian-Kang Zhu -- The use of yeast genetic tools to define biological roles of novel protein phosphatases / Joaquín Ariño ... [et al.] -- Targeting of PP2C in budding yeast / Irene Ota and James Mapes -- Phosphatase targets in TOR signaling / Estela Jacinto -- Functional characterization of the small CTD phosphatases (SCPs) / Michele Yeo and Patrick S. Lin -- Genome-scale discovery and characterization of class-specific protein sequences / David Kerk -- Yeast substrate-trapping system for isolating substrates of protein tyrosine phosphatases / Masahide Fukada and Masaharu Noda.
  • 2003 ScienceDirect
    edited by Susanne Klumpp, Josef Krieglstein.
    Section I. Determination, detection, and localization -- Section II. Interacting proteins and subunits -- Section III. Inhibition, stimulation, and modulation of activity -- Section IV. Expression systems -- Section V. Knockdown and knockout technologies.
    Also available: Print – 2003
  • ScienceDirect
    edited by Tony Hunter, Bartholomew M. Sefton.
    Also available: Print – 1991
  • ScienceDirect
    edited by Tony Hunter, Bartholomew M. Sefton.
    Also available: Print – 1991
  • 2009 Springer
    edited by John M. Walker.
    Quantitation of proteins -- Electrophoresis of proteins and peptides and detection in gels -- Blotting and detection methods -- Chemical modification of proteins and peptide production and purification -- Posttranslational modifications -- Antibody techniques.
  • 2011 Wiley
    edited by Jan-Christer Janson.
    Introduction to protein purification / B. Ersson, L. Rydén and J.-C. Janson -- Introduction to chromatography / J.-C. Janson and J.Å. Jönsson -- Gel filtration: Size exclusion chromatography / L. Hagel -- Ion exchange chromatography / E. Karlsson and I. Hirsh -- High-resolution reversed-phase chromatography of proteins / S.W. Pettersson -- Hydrophobic interaction chromatography / K.-O. Eriksson and M. Belew -- Immobilized metal ion affinity chromatography / L. Kågedal -- Covalent chromatography / F. Batista-Viera, L. Rydén and J. Carlsson -- Affinity chromatography / F. Batista-Viera, J.-C. Janson and J. Carlsson -- Affinity ligands from chemical combinatorial libraries / E. Carredano and H. Baumann -- Affinity ligands from biological combinatorial libraries / P.-Å. Nygren -- Membrane separations / J.K. Walter [and others] -- Refolding of inclusion body proteins from E. coli / Z. Su, D. Lu and Z. Liu -- Purification of PEGylated proteins / C.J. Fee and J.M. Van Alstine -- Electrophoresis in gels / R. Westermeier -- Conventional isoelectric focusing in gel slabs and capillaries and immobilized pH gradients / P.G. Righetti, E. Fasoli and S.C. Righetti -- Two-dimensional electrophoresis in proteomics / R. Westermeier and A. Görg -- Protein elution and blotting techniques / R. Westermeier -- Capillary electrophoretic separations / W. Thormann -- High throughput screening techniques in protein purification / K.M. Lacki and E. Brekkan.
    Also available: Print – v. 54, 2011.
  • 2013 Springer
    Richard I. Morimoto, Yves Christen, editors.
    The health of the proteome depends upon protein quality control to regulate the proper synthesis, folding., translocation, and clearance of proteins. The cell is challenged constantyl by environmental and physiological stress, aging, and the chronic expressions of disease associated misfolded proteins. Substantial evidence supports the hypothesis that the expression of damaged proteins initiates a cascade of molecular events that leads to Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, and other diseases of protein conformation.
  • 2002 ScienceDirect
    edited by Helmut Sies, Lester Packer ; editorial advisory board, Bob Buchanan ... [et al.].
    Also available: Print – 2002
  • 2002 ScienceDirect
    edited by Helmut Sies, Lester Packer ; editorial advisory board, Bob Buchanan ... [et al.].
    Also available: Print – 2002
  • 2008 Springer Protocols
    edited by Mohammed J. Zaki and Christopher Bystroff.
    A historical perspective of template-based protein structure prediction / Jun-tao Guo, Kyle Ellrott, and Ying Xu -- The assessment of methods for protein structure prediction / Anna Tramontaro ... [et al.] -- Aligning sequences to structures / Liam James McGuffin -- Protein structure prediction using threading / Jinbo Xu, Feng Jiao, and Libo Yu -- Algorithms for multiple protein structure alignment and structure-derived multiple sequence alignment / Maxim Shatsky, Ruth Nussinov, and Haim J. Wolfson -- Indexing protein structures using suffix trees / Feng Gao and Mohammed J. Zaki -- Hidden Markov models for prediction of protein features / Christopher Bystroff and Anders Krogh -- The pros and cons of predicting protein contact maps / Lisa Bartoli ... [et al.] -- Roadmap methods for protein folding / Mark Moll, David Schwarz, and Lydia E. Kavraki -- Scoring functions for de novo protein structure prediction revisited / Shing-Chung Ngan ... [et al.] -- Protein-protein docking : overview and performance analysis / Kevin Wiehe ... [et al.] -- Molecular dynamics simulations of protein folding / Angel E. Garcia.
  • 2014 Springer Protocols
    edited by Daisuke Kihara.
    Protein structure modeling with MODELLER / Benjamin Webb and Andrej Sali -- RaptorX server : a resource for template-based protein structure modeling / Morten Källberg ... [et al.] -- MULTICOM protein tertiary structure prediction system / Jilong Li ... [et al.] -- Modeling of protein side-chain conformations with RASP / Zhichao Miao, Yang Cao, and Taijiao Jiang -- Direct coupling analysis for protein contact prediction / Faruck Morcos ... [et al.] -- ITScorePro : an efficient scoring program for evaluating the energy scores of protein structures for structure prediction / Sheng-You Huang and Xiaoqin Zou -- Assessing the quality of modelled 3D protein structures using the ModFOLD server / Daniel Barry Roche, Maria Teresa Buenavista, and Liam James McGuffin -- 3D-SURFER 2.0 : web platform for real-time search and characterization of protein surfaces / Yi Xiong ... [et al.] -- SPOT-Seq-RNA : predicting protein-RNA complex structure and RNA-binding function by fold recognition and binding affinity prediction / Yuedong Yang ... [et al.] -- POODLE : Tools Predicting Intrinsically Disordered Regions of Amino Acid Sequence / Kana Shimizu -- Prediction of intrinsic disorder in proteins using MFDp2 / Marcin J. Mizianty, Vladimir Uversky, and Lukasz Kurgan -- Modeling protein-protein complexes using the HADDOCK webserver "modeling protein complexes with HADDOCK" / Gydo C.P. van Zundert and Alexandre M.J.J. Bonvin -- Predicting the structure of protein-protein complexes using the swarmdock web server / Mieczyslaw Torchala and Paul A. Bates -- DOCK/PIERR : web server for structure prediction of Protein-protein complexes / Shruthi Viswanath, D.V.S. Ravikant, and Ron Elber -- Pairwise and multimeric protein-protein docking using the LZerD program Suite / Juan Esquivel-Rodriguez ... [et al.] -- Protocols for efficient simulations of long-time protein dynamics using coarse-grained CABS model / Michal Jamroz, Andrzej Kolinski, and Sebastian Kmiecik.
  • 2012 Springer Protocols
    edited by Alexander E. Kister.
  • 2016 Springer
    Thomas Böldicke, editor.
    Introduction -- Part I Methods of Structure Prediction -- Chapter 1 In Silico Prediction of Target-Inhibitor Interactions -- Part II Antibodies -- Chapter 2 Antibodies and Selection of Monoclonal Antibodies -- Chapter 3 Selection of Recombinant Human Antibodies -- Chapter 4 Selection of Recombinant Human Antibodies against Toxins and Viruses -- Chapter 5 Recent Advances with ER Targeted Intrabodies -- Chapter 6 Therapeutic Blocking Antibodies against Oncogenic Receptors and Growth Factors -- Chapter 7 Synthetic Cystine-Knot Miniproteins-Valuable Scaffolds for Polypeptide Engineering -- Part III Peptides, Small Molecules and Aptamers -- Chapter 8 Peptides and Peptide Analogs to Inhibit Protein -- Chapter 9 Allosteric Modulators of the Class A G Protein coupled Receptors -- Chapter 10 Phosphatases: Their Roles in Cancer and their Chemical Modulators -- Chapter 11 Selection and Application of Aptamers and Intramers -- Part IV Angiogenesis Inhibitors -- Chapter 12 Inhibitors of Angiogenesis.
    Also available: Print – 2016
  • 2006 Springer
    edited by Doriano Fabbro and Frank McCormick.
    Protein tyrosine kinases as targets for cancer and other indications / Mark Pearson, Carlos Garcia-Echeverria, Doriano Fabbro -- Inhibitors of signaling interfaces: targeting Src homology 2 domains in drug discovery / Carlos Garcia-Echeverria -- PI 3-kinase inhibition: a target for therapeutic intervention / Peter M. Finan, Stephen G. Ward -- Src as a target for pharmaceutical intervention: potential and limitations / Mira Susa ... [et al.] -- Activated FLT3 receptor tyrosine kinase as a therapeutic target in leukemia / Blanca Scheijen, James D. Griffin -- JAK kinases in leukemias/lymphomas and multiple myeloma / Renate Burger, Martin Gramatzki -- Glivec (Gleevec, Imatinib, STI571): a targeted therapy for CML / Elisabeth Buchdunger, Renaud Capedeville -- Platelet-derived growth factor: normal function, role in disease, and applications of PDGF antagonists / Tobias Sjoblom ... [et al.] -- Structural biology of protein tyrosine kinases / Sandra W. Cowan-Jacob ... [et al.] -- Testing of signal transduction inhibitors in animal models of cancer / Terence O'Reilly, Robert Cozens -- Phosphoproteomics in drug discovery and development / Michel F. Moran.
    Also available: Print – 2006
  • 2013 Springer
    Kendra K. Bence, editor.
    Tyrosine phosphorylation is a rapid and reversible protein modification catalyzed by the yin and yang activities of protein tyrosine kinases (PTKs) and protein tyrosine phosphatases (PTPs). A multitude of PTPs have been implicated in human disease, with a growing number of PTPs now known to play major roles in prevalent metabolic diseases including obesity and type 2 diabetes. Recent studies into PTP function in the context of metabolism highlight the importance of understanding the specific substrates and binding partners of these enzymes, the regulation of PTP activity, and the cell/tissue specificity of PTP functions. This volume contains chapters which highlight many aspects of PTP function in the context of metabolism.
  • ScienceDirect
    edited by Robert T. Sauer.
    Also available: Print – 1991
  • 2013 Springer Protocols
    edited by Mark A. Williams, Tina Daviter.
    Protein-ligand interactions : fundamentals / Mark A. Williams -- Protein sample characterization / Tina Daviter and Remi Fronzes -- Measurement of protein-ligand complex formation / Peter N. Lowe, Cara K. Vaughan, and Tina Daviter -- Isothermal titration calorimetry for studying protein-ligand interactions / Luminita Damian -- Rapid mixing kinetic techniques / Stephen R. Martin and Maria J. Schilstra -- Protein-ligand interactions using SPR systems / Asa Frostell, Lena Vinterback, and Hans Sjobom -- Fluorescence techniques in analysis of protein-ligand interactions / Gabor Mocz and Justin A. Ross -- Circular and linear dichroism spectroscopy for the study of protein-ligand interactions / Tina Daviter, Nikola Chmel, and Alison Rodger -- Analyzing protein-ligand interactions by dynamic NMR spectroscopy / Anthony Mittermaier and Erick Meneses -- Studying metal ion-protein interactions : electronic absorption, circular dichroism, and electron paramagnetic resonance / Liliana Quintanar and Lina Rivillas-Acevedo -- Monitoring protein-ligand interactions by time-resolved FTIR difference spectroscopy / Carsten Kotting and Klaus Gerwert -- Biophysical methods in drug discovery from small molecule to pharmaceutical / Geoffrey Holdgate [and others] -- Biophysical screening for the discovery of small-molecule ligands / Alessio Ciulli -- Screening protein-small molecule interactions by NMR / Ben Davis -- Model membrane systems / Heiko Keller, Remigiusz Worch, and Petra Schwille -- Quantitative fluorescence co-localization to study protein-receptor complexes / Shanica N. Pompey, Peter Michaely, and Katherine Luby-Phelps -- Studying protein-ligand interactions using X-ray crystallography / Andrew P. Turnbull and Paul Emsley -- Molecular fields in ligand discovery / Paul J. Gane and A.W. Edith Chan -- Structure-based virtual screening for novel ligands / William R. Pitt [and others].
  • 2008 Springer
    Enno Klussmann, John Scott, editors ; contributors, E.M. Aandahl ... [et al.].
  • 2007/2008
    Andres Bayani Tellez.
    Status: Not Checked OutLane Catalog Record
  • 2010 Springer
    edited by Gregor Anderluh, Jeremy Lakey.
    Energetics of peptide and protein binding to lipid membranes / William C. Wimley -- Membrane association and pore formation by alpha-helical peptides / Burkhard Bechinger -- Role of membrane lipids for the activity of pore forming peptides and proteins / Gustavo Fuertes ... [et al.] -- Cholesterol-dependent cytolysins / Robert J.C. Gilbert -- Laetiporus sulphureus lectin and aerolysin protein family / Jose Miguel Manchero .. [et al.] -- Interfacial interactions of pore-forming colicins / Helen Ridley, Christopher L. Johnson and Jeremy H. Lakey -- Permeabilization of the outer mitochondrial membrane by BCL-2 proteins / Ana J. Garcia-Suez ... [et al.] -- Molecular mechanism of sphingomyelin : specific membrane binding and pore formation by actinoporins / Biserka Bakra and Gregor Anderluh -- Hemolysin E (hlye, clya, shea) and related toxins / Stuart Hunt, Jeffrey Green and Peter J. Artymiuk -- Pore formation by cry toxins / Mario Soberin ... [et al.] -- Role of heparan sulfates and glycosphingolipids in the pore formation of basic polypeptides of cobra cardiotoxin / Wen-guey Wu ... [et al.] -- Amyloid peptide pores and the beta sheet conformation / Bruce L. Kagan and Jyothi Thundimadathil.
    Also available: Print – 2010
  • 2014 Springer
    André L.S. Santos, Marta H. Branquinha, Claudia M. d'Avila-Levy, Lucimar F. Kneipp, Cátia L. Sodré, editors.
    This book contains a collection of critical reviews on the expression of biologically functional proteins in Leishmania and Trypanosoma, which was written by renowned researchers on this field. Species belonging to these trypanosomatids genera are etiological agents of leishmaniasis, Chagas' disease and sleeping sickness that are extremely debilitating human infection diseases, which remain a major health problem especially in countries from Latin America, Africa and Middle East. Substantiating the problem, the currently accepted drugs for these diseases are quite unsatisfying due to their low efficacy and high toxicity. In order to solve these real problems, several research groups around the world have become involved in the study and identification of novel potential targets in the trypanosomatid cell. Since proteins are key macromolecules involved in crucial metabolic processes of all living cells, studies have focused on the expression of specific proteins produced by Leishmania and Trypanosoma by means of different biochemical, molecular and proteomic approaches in order to explore them as targets for understanding the parasite life cycle and developing new strategies against trypanosomiasis. With these proposals in mind, the book "Proteins and Proteome of Leishmania and Trypanosoma" encompasses (i) an integrated view about the biochemistry of parasites belonging to the Leishmania and Trypanosoma genera; (ii) an updated review on the expression of biologically relevant proteins by human pathogenic trypanosomatids and their possible role in the interaction with host cells/molecules as well as a target for development of both alternative chemotherapies and vaccine; and (iii) several pictures, diagrams and tables that can be used to illustrate both undergraduate and postgraduate teaching as well as scientific lectures, being a useful resource for students and researchers.
  • 2005 ScienceDirect
    Edward J. Thompson.
  • 2013 Springer
    Danton O'Day, Andrew Catalano, editors.
    This book contains 14 original review chapters each yielding new, exciting and intriguing data about the emerging understanding of nucleolar structure and function in normal, stressed and diseased cells. The goal of this work is to provide special insight into the nucleolus of the past, present and future, as well its regulation, translocation, and biomedical function. A multitude of topics are introduced and discussed in detail, including nucleologenesis, nucleolar architecture, nucleolar targeting, retention, anchoring, translocation, and the relationship between the nucleolus and cancer.
  • 2012 Springer Protocols
    edited by Francoise Redini.
    Proteoglycans : gene cloning -- Proteoglycan : site mapping and site-directed mutagenesis -- Mapping of the wnt/beta-catenin/TCF response elements in the human versican promoter -- Gene silencing in mouse embryonic stem cells -- A novel strategy for a splice-variant selective gene ablation : the example of the versican v0/v2 knockout -- Detection of neurocan in cerebrospinal fluid -- Glycosaminoglycan chain analysis and characterization (glycosylation/epimerization) -- Characterization of glycosaminoglycans by tandem vibrational microspectroscopy and multivariate data analysis -- Glycosaminoglycans : oligosaccharide analysis by liquid chromatography, capillary electrophoresis, and specific labeling -- Brain chondroitin/dermatan sulfate, from cerebral tissue to fine structure : extraction, preparation, and fully automated chip-electrospray mass spectrometric analysis -- Use of neutrons reveals the dynamics of cell surface glycosaminoglycans -- Following protein-glycosaminoglycan polysaccharide interactions with differential scanning fluorimetry -- In vivo scintigraphic imaging of proteoglycans -- Serglycin : the master of the mast cell -- Analysis of aggrecan catabolism by immunoblotting and immunohistochemistry -- Heparan sulfate proteoglycans as multifunctional cell regulators : cell surface receptors -- Models for studies of proteoglycans in kidney pathophysiology -- Lumican promotes corneal epithelial wound healing -- Shedding of cell membrane-bound proteoglycans -- Modulatory effects of proteoglycans on proteinase activities -- Proteoglycans and osteolysis -- Proteoglycans and cartilage repair.
  • ScienceDirect
    edited by Alan J. Barrett.
    Also available: Print – 1995
  • pt. A-B, 1993. ScienceDirect
    pt. B ScienceDirect
    edited by Laszlo Lorand, Kenneth G. Mann.
    Pt. A. Mammalian blood coagulation factors and inhibitors -- Pt. B. Complement activation, fibrinolysis, and nonmammalian blood coagulation factors and inhibitors.
    Also available: Print – pt. A-B, 1993.
  • ScienceDirect
    edited by Gertrude E. Perlmann and Laszlo Lorand.
    Also available: Print – 1970
  • ScienceDirect
    edited by Laszlo Lorand.
    Also available: Print – 1976
  • ScienceDirect
    edited by Laszlo Lorand.
    Also available: Print – 1981
  • ScienceDirect
    edited by Alan J. Barrett.
    Also available: Print – 1994
  • 2007 Springer
    M.R. Wilkins ... [et al.], eds.
    Also available: Print – 2007
  • 2013 ScienceDirect
    edited by Haleem J. Issaq, Timothy D. Veenstra.
    Proteomic and Metabolomic Approaches to Biomarker Discovery demonstrates how to leverage biomarkers to improve accuracy and reduce errors in research. Disease biomarker discovery is one of the most vibrant and important areas of research today, as the identification of reliable biomarkers has an enormous impact on disease diagnosis, selection of treatment regimens, and therapeutic monitoring. Various techniques are used in the biomarker discovery process, including techniques used in proteomics, the study of the proteins that make up an organism, and metabolomics, the study of chemical fingerprints created from cellular processes. Proteomic and Metabolomic Approaches to Biomarker Discovery is the only publication that covers techniques from both proteomics and metabolomics and includes all steps involved in biomarker discovery, from study design to study execution. The book describes methods, and presents a standard operating procedure for sample selection, preparation, and storage, as well as data analysis and modeling. This new standard effectively eliminates the differing methodologies used in studies and creates a unified approach. Readers will learn the advantages and disadvantages of the various techniques discussed, as well as potential difficulties inherent to all steps in the biomarker discovery process. A vital resource for biochemists, biologists, analytical chemists, bioanalytical chemists, clinical and medical technicians, researchers in pharmaceuticals, and graduate students, Proteomic and Metabolomic Approaches to Biomarker Discovery provides the information needed to reduce clinical error in the execution of research. Describes the use of biomarkers to reduce clinical errors in research. Includes techniques from a range of biomarker discoveries. Covers all steps involved in biomarker discovery, from study design to study execution.
  • 2013
    Nicholas Collins Weiler.
    Plasticity of connections within the neocortical microcircuit is thought to be the substrate for perceptual learning and memory. Mouse whisker barrel cortex offers many unique experimental advantages for the study of neocortical plasticity because of an accessible sensory periphery and a repeated, stereotyped columnar architecture. These features make it possible to characterize the microcircuitry of the cortical column, a potential common circuit element across species and cortical areas. I have developed an experimental and computational pipeline for characterizing the distribution of molecularly distinct synapse populations within whisker barrel columns using array tomography, a technique developed in our laboratory. I have performed preliminary explorations of modifications of the synaptic architecture of the mouse barrel cortex microcircuit produced by a brief period of sensory deprivation during early adulthood, and identify specific synapse populations most subject to such modification. I have also worked with collaborators at the Open Connectome Project to host this data and my software publicly online so that others can also mine it to explore the proteomic complexity of synaptic microcircuits.
  • 2015 Springer Protocols
    edited by Anton Posch.
    Mechanical/physical methods of cell distribution and tissue homogenization / Stanley Goldberg -- Sample preservation through heat stabilization of proteins : principles and examples / Mats Borén -- Isolating peripheral lymphocytes by density gradient centrifugation and magnetic cell sorting / Frederic Brosseron, Katrin Marcus, and Caroline May -- Investigating the adipose tissue secretome : a protocol to generate high-quality samples appropriate for comprehensive proteomic profiling / Simon Göddeke, Jorg Kotzka, and Stefan Lehr -- Methods for proteomics-based analysis of the human muscle secretome using an in vitro exercise model / Mika Scheler ... [et al.] -- Urinary pellet sample preparation for shotgun proteomic analysis of microbial infection and host-pathogen interactions / Yanbao Yu and Rembert Pieper -- Protocol for the parallel isolation of intact mitochondria from rat liver, kidney, heart, and brain / Sabine Schulz ... [et al.] -- Isolation of mitochondria from cultured cells and liver tissue biopsies for molecular and biochemical analyses / Sabine Schmitt ... [et al.] -- Dynamic range compression with ProteoMiner : principles and examples / Lei Li -- Qualitative and quantitative proteomic analysis of formalin-fixed paraffin-embedded (FFPE) tissue / Omid Azimzadeh, Michael J. Atkinson, and Soile Tapio -- Full-length protein extraction protocols and gel-based downstream applications in formalin-fixed tissue proteomics / Alessandro Tanca, Sergio Uzzau, and Maria Filippa Addis -- Enrichment of low-abundant protein targets by immunoprecipitation upstream of mass spectrometry / Barbara Kaboord ... [et al.] -- Principles of protein labeling techniques / Christian Obermaier, Anja Griebel, and Reiner Westermeier -- Isolation of extracellular vesicles for proteomic profiling / Dong-Sic Choi and Yong Song Gho -- Protocol for exosome isolation and characterization : evaluation of ultracentrifugation, density-gradient separation, and immunoaffinity capture methods / David W. Greening ... [et al.] -- Chloroplast isolation and affinity chromatography for enrichment of low-abundant proteins in complex proteomes / Roman G. Bayer, Simon Stael, and Markus Teige -- Depletion of RuBisCO protein using the protamine sulfate precipitation method / Ravi Gupta and Sun Tae Kim -- Step-by-step preparation of proteins for mass spectrometric analysis / Thomas Franz and Xinping Li -- Identification of protein N-Termini using TMPP or dimethyl labeling and mass spectrometry / Jingjing Deng ... [et al.] -- Optimization of cell lysis and protein digestion protocols for protein analysis by LC-MS/MS / Dominic Winter, Alireza Dehghani, and Hanno Steen -- Comprehensive protocol to simultaneously study protein phosphorylation, acetylation, and n-linked sialylated glycosylation / Marcella Nunes Melo-Braga ... [et al.] -- Protein profiling and phosphoprotein analysis by isoelectric focusing / Giuseppina Maccarrone and Michaela D. Filiou -- Principles and examples of gel-based approaches for phosphoprotein analysis / Birgit Steinberger and Corina Mayrhofer -- Neutral phosphate-affinity SDS-PAGE system for profiling of protein phosphorylation / Emiko Kinoshita-Kikuta, Eiji Kinoshita, and Tohru Koike -- Enrichment and identification of bacterial glycopeptides by mass spectrometry / Nichollas E. Scott and Stuart J. Cordwell -- In-gel peptide IEF sample preparation for LC/MS analysis / Tom Berkelman, Sricharan Bandhakavi, and Aran Paulus -- Western blotting using in-gel protein labeling as a normalization control : stain-free technology / Jennifer E. Gilda and Aldrin V. Gomes -- 2-D western blotting for evaluation of antibodies developed for detection of host cell protein / Tom Berkelman, Adriana Harbers, and Sricharan Bandhakavi -- Free llow electrophoresis for separation of native membrane protein complexes / Lutz Andreas Eichacker ... [et al.] -- Three-dimensional electrophoresis for quantitative profiling of complex proteomes / Sergio Mauro ... [et al.] -- Bead-based multiplex sandwich immunoassay to assess the abundance and posttranslational modification state of [beta]-catenin / Nicola Groll ... [et al.] -- Identification of SUMO E3 ligase-specific substrates using the huprot human proteome microarray / Eric Cox ... [et al.] -- Amyloid-binding proteins : affinity-based separation, proteomic identification, and optical biosensor validation / Alexei Medvedev ... [et al.] -- Proteomic profiling by nanomaterials-based matrix- assisted laser desorption/ionization mass spectrometry for high-resolution data and novel protein information directly from biological samples / Suresh Kumar Kailasa and Hui-Fen Wu.
  • 2013 ScienceDirect
    [edited by] Pawel Ciborowski, Jerzy Silberring.
    This book is designed to help scientists without a strong background in analytical chemistry to understand basic analytical principles so they can apply them to proteomics profiling. It will also help researchers with an analytical chemistry background to break into the proteomics field. The title focuses on practical applications for proteomic research so readers are guided to design better experiments and to more easily interpret the resulting data. Bridges the gap between overly specialized courses and books in mass spectrometry, proteomics and analytical chemistryCovers the analytical consequences of protein and peptide modifications that may have a profound effect on how and what researchers actually measure; other books do not discuss such issuesIncludes real life examples illustrating the importance of problems in quantitation and validation of biomarkers from the perspective of analytical chemistry with additional references to other sources Helps in designing and executing proteomic experiments with sound analytics.
  • 2011
    Brad Busse.
    Array tomography (AT) is a high-resolution proteomic imaging method that exploits a combination of light and EM techniques to resolve fine details at the synapse level across large fields of view spanning entire circuits. Much of my graduate work has centered on helping to shape AT into an imaging method fit for rigorous use, by developing computational algorithms which take advantage of AT's particular qualities to automate its operation. Among them are: a mapping tool for microscopy software to automate the imaging of AT's unique section layout; Multistackreg, an alignment plugin which is capable of registering multiple imaging sessions on the same piece of tissue; a cross-correlation algorithm for fluorescent channel validation; the synaptogram, a tool for visualizing synapse-scale high-dimensional proteomic molecular complexes; and an active learning paradigm for large-scale synapse quantification.
  • 2014 Karger
    volume editor, Daniel Martins-de-Souza.
    Proteomic characterization of the brain and cerebrospinal fluid of schizophrenia patients / Caf-Mendes, C.C.; Gattaz, W.F.; Schmitt, A.; Britto, L.R.G.; Martins-de-Souza, D -- Peripheral biomarker candidates in schizophrenia / Thome, J.; Bratek, A.; Krysta, K -- Schizophrenia : blood-serum-plasma metabolomics / Lista, S.; Giegling, I.; Rujescu, D -- Proteomic and metabolomic evidence for glial alterations in schizophrenia / Beasley, C.L.; Barakauskas, V.E -- Insights from proteomic studies on schizophrenia preclinical models : what can we learn for drug discovery? / Farrelly, L.A.; Fcking, M.; Cotter, D.R -- Metabolomics to study psychotic disorders and their metabolic comorbidities / Oresi, M -- Peripheral biomarkers for depression by plasma and serum proteomics / Domenici, E -- Proteomics of preclinical models of depression / Carboni, L -- Antidepressant response metabonomics / Qin, X.; Gao, X.; Qiao, Y.; Zhou, Y.; Tian, J.; Li, Z -- Proteomics and metabolomics of bipolar disorder / Sussulini, A -- Use of metabolomics and proteomics to reveal pathophysiological pathways in anxiety disorders / Altmaier, E.; Emeny, R.T.
  • 2005 Springer
    edited by Gabriel Waksman.
  • 2013 Springer Protocols
    edited by Ming Zhou and Timothy Veenstra.
    Affinity depletion of plasma and serum for mass spectrometry-based proteome analysis / Julian A.J. Jaros ... [et al.] -- Tissue sample preparation for biomarker discovery / Yoshiyuki Suehara, Daisuke Kubota, and Tsuyoshi Saito -- Subcellular fractionation for identification of biomarkers : serial detergent extraction by subcellular accessibility and solubility / Sun-II Hwang and David K. Han -- Analysis of secreted proteins / Valeria Severino, Annarita Farina, and Angela Chambery -- Preparation of human cerebrospinal fluid for proteomics biomarker analysis / Timothy J. Waybright -- Proteomic analysis of frozen tissue samples using laser capture microdissection / Sumana Mukherjee ... [et al.] -- Use of formalin-fixed, paraffin-embedded tissue for proteomic biomarker discovery / David B. Krizman and Jon Burrows -- Phosphopeptide enrichment using offline titanium dioxide columns for phosphoproteomics / Li-Rong Yu and Timothy Veenstra -- iTRAQ-labeling for biomarker discovery / Leroi V. DeSouza, Sébastien N. Voisin, and K.W. Michael Siu -- Analysis of glycoproteins for biomarker discovery / Jintang He ... [et al.] -- SILAC in biomarker discovery / Benjamin C. Orsburn -- Trypsin-mediated 18O/16O labeling for biomarker discovery / Xiaoying Ye ... [et al.] -- Two-dimensional SDS-PAGE fractionation of biological samples for biomarker discovery / Thierry Rabilloud and Sarah Triboulet -- Informatics of protein and posttranslational modification detection via shotgun proteomics / Jerry D. Holman, Surendra Dasari, and David L. Tabb -- Quantitation of met tyrosine phosphorylation using MRM-MS / Zhaojing Meng -- Preparation of human serum for prolactin measurement by multiple reaction monitoring mass spectrometry / Timothy J. Waybright ... [et al.] -- Label-free quantitative shotgun proteomics using normalized spectral abundance factors / Karlie A. Neilson ... [et al.] -- Employment of complementary dissociation techniques for body fluid characterization and biomarker discovery / David M. Good and Dorothea Rutishauser -- Phosphopeptide microarrays for comparative proteomic profiling of cellular lysates / Liqian Gao ... [et al.] -- Tissue preparation for MALDI-MS imaging of protein and peptides / Simona Colantonio and Roberta M. Smith -- Plant proteogenomics : from protein extraction to improved gene predictions / Brett Chapman ... [et al.] -- Label-free differential analysis of murine postsynaptic densities / Scott P. Goulding, Michael J. MacCoss, and Christine C. Wu -- Fractionation of peptides by strong cation-exchange liquid chromatography / King C. Chan and Haleem J. Issaq.
  • 2008 Karger
    volume editor, Visith Thongboonkerd.
    Proteomics for the investigation of acute kidney injury / P. Devarajan -- Proteomics of plasma and urine in primary nephrotic syndrome in children / G. Candiano ... [et al.] -- Urinary proteome profiling to search for biomarkers in steroid-resistant nephrotic syndrome / A.Z. Traum, A.D. Schachter -- Searching for novel biomarkers and new therapeutic targets of diabetic nephropathy using proteomics approaches / V. Thongboonkerd -- Diagnostic and prognostic biomarkers in acute renal failure / J.M. Arthur ... [et al.] -- Proteomics and renal transplantation : searching for novel biomarkers and therapeutic targets / S. Schaub, J.A. Wilkins, P. Nickerson -- Metabolomics : a complementary tool in renal transplantation / D.S. Wishart -- Understanding and managing renal cell carcinoma : can proteomic studies contribute to clinical practice? -- R.A. Craven, R.E. Banks -- Capillary electrophoresis coupled to mass spectrometry for biomarker discovery and diagnosis of kidney diseases / P. Zürbig, H. Mischak -- Identification of urinary biomarkers by proteomics in newborns : use in obstructive nephropathy / S. Decramer ... [et al.] -- Proteomics and kidney stone disease / V. Thongboonkerd -- Exploring the uremic toxins using proteomic technologies / E. Schiffer -- Proteomic approaches for the study of cell signaling in the renal collecting duct / E.J. Hoorn -- Overview of kidney and urine proteome databases / Y. Yoshida ... [et al.].
    Also available: Print – 2008
  • 2007 Springer
    edited by Visith Thongboonkerd.
    Proteomic strategies for analyzing body fluids / Sung-Min Ahn and Richard J. Simpson -- Sample preparation of body fluids for proteomics analysis / Natalia Govorukhina and Rainer Bischoff -- Multiplexed immunoassays for protein profiling in human body fluids / Silke Wittemann ... [et al.] -- Deciphering the hieroglyphics of functional proteomics using small molecule probes / Wayne F. Patton -- Modification-specific proteomic analysis of glycoproteins in human body fluids by mass spectrometry / Jakob Bunkenborg, Per Hagglund, and Ole N. Jensen -- Plasma proteome database / Malabika Sarker, G. Hanumanthu, and Akhilesh Pandey -- 2D PAGE databases for proteins in human body fluids / Christine Hoogland ... [et al.] -- Bioinformatics and experimental design for biomarker discovery / Marc R. Wilkins and Sybille M.N. Hunt -- Integrative omics, pharmacoproteomics and human body fluids / K.K. Jain -- The human plasma and serum proteome / Gilbert S. Omenn ... [et al.] -- Proteomics of human urine / Visith Thongboonkerd ... [et al.] -- Proteomics of human cerebrospinal fluid / Margareta Ramström and Jonas Bergquist -- Proteomics of pleural effusion / Joost Hegmans, Annabrita Hemmes, and Bart Lambrecht -- Proteomics of bronchoalveolar lavage fluid and sputum / Ruddy Wattiez, Olivier Michel, and Paul Falmagne -- Proteomics of sinusitis nasal lavage fluid / Begona Casado, Simona Viglio, and James N. Baraniuk -- Proteomics of human saliva / Francisco M.L. Amado ... [et al.] -- Proteomics of human pancreatic juice / Mads Granborg, Anirban Maitra, and Akhilesh Pandey -- Proteomics of human bile / Troels Z. Kristiansen, Anirban Maitra, and Akhilesh Pandey -- Proteomics of amniotic fluid / David Crettaz ... [et al.] -- Proteomics of human milk / Amedeo Conti, Maria G. Giuffrida, and Maria Cavaletto -- Proteomics of nipple aspirate fluid in non-lactating women / Edward R. Sauter -- Proteomics of seminal fluid / Benjamin Solomon and Mark W. Duncan -- Proteomics of vitreous fluid / Atsushi Minamoto, Ken Yamane, and Tomoko Yokoyama -- Proteomics of human dialysate and ultrafiltrate fluids yielded by renal replacement therapy / Michael Walden ... [et al.].
  • 2005 Springer
    G.S. Gupta.
  • 2005 Springer
    2005 Springer Protocols
    edited by John M. Walker.
  • 2013 Springer
    Mathias Jucker, Yves Christen, editors.
    The misfolding and aggregation of specific proteins is an early and obligatory event in many of the age-related neurodegenerative diseases of humans, and appears to occur many years before the onset of clinical symptoms. The initial cause of this pathogenic cascade and the means whereby disease spreads through the nervous system, remain uncertain. A recent surge of research, first instigated by pathologic similarities between prion disease and Alzheimer's disease, has increasingly implicated corruptive protein templating, or seeding, as a prime factor in the neurodegenerative process. The prion-like corruption of proteins also characterizes such clinically and etiologically diverse neurological disorders as Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, and frontotemporal lobar degeneration. Understanding the misfolding, aggregation, trafficking and pathogenicity of affected proteins thus could reveal universal principles and common therapeutic targets for some of the most devastating and intractable human brain disorders.
  • v. 2, 1938.
    Saizar, Pedro.
    Status: Not Checked OutLane Catalog Record
    Contents -- t. 2. Dientes artificiales. Materiales de base. Diagnóstico. Preparación quirúrgica. Prótesis inmediata. Reparaciones. Organismo y prótesis. Historia.
  • 2005 Springer
    edited by S. Mohan Jain and Pramod K. Gupta.
  • 2008 Springer
    Andrea Laghi.
  • 2009 Springer
    Andrea Laghi, Marco Rengo.
  • 2009 Springer
    Alessandro Bozzao.
  • 2009 Springer
    Andrea Laghi, Riccardo Ferrari.
  • 2016 Springer
    Guillem Pons-Lladó, editor.
    1. MR sequences for cardiovascular applications and planning of studies -- 2. Study protocol for Ischemic Heart Disease -- 3. Study protocol for Cardiomyopathies -- 4. Study protocol for Pericardial Diseases -- 5. Study protocol for Cardiac Masses and Tumors -- 6. Study protocol for Great Vessels -- 7. Study protocol for Valvular Heart Disease -- 8. Study protocol for Congenital Heart Disease -- 9. Protocols for the practice of cardiac studies by Computed Tomography -- 10. Post-processing and analysis of Cardiac CT studies.
  • 2009 Springer Protocols
    edited by S. Mohan Jain and Praveen K. Saxena.
    Establishment of adventitious root cultures of Echinacea purpurea for the production of caffeic acid derivatives / K.Y. Paek, H.N. Murthy and E.J. Hahn -- In vitro propagation of Rauwolfia serpentina using liquid medium, assessment of genetic fidelity of micropropagated plants, and simultaneous quantitation of reserpine, ajmaline, and ajmalicine / M.K. Goel ... [et al.] -- Medicinal properties, in vitro protocols and secondary metabolite analyses of Scots pine / H. Haggman ... [et al.] -- Saussurea medusa cell suspension cultures for flavonoid production / C.Z. Liu and P.K. Saxena -- Large-scale in vitro multiplication of Crataeva nurvala / S.B. Babbar, N. Walia and A. Kaur -- Bilberry in vitro protocols and analyses of phenolic compounds / L. Jaakola ... [et al.] -- In vitro propagation of two tuberous medicinal plants: Holostemma ada-kodien and Ipomoea mauritiana / S.P. Geetha ... [et al.] -- In vitro production of gymnemic acid from Gymnema sylvestre (Retz) R. Br. Ex Roemer and Schultes through callus culture under abiotic stress conditions / A.B. Ali Ahmed, A.S. Rao and M.V. Rao -- Establishment of plant regeneration and cryopreservation system from zygotic embryo-derived embryogenic cell suspension cultures of Ranunculus kazusensis / S.W. Kim and M.J. Oh -- In vitro culture and secondary metabolite isolation in bryophytes / A. Sabovljevic, M. Sabovljevic and N. Jockovic -- Micropropagation and in vitro conservation of vanilla (Vanilla planifolia Andrews) / M. Divakaran and K.N. Babu -- Protocol for in vitro regeneration and marker glycoside assessment in Swertia chirata Buch-Ham / S. Koul ... [et al.] -- Protocols for establishment of an in vitro collection of medicinal plants in the genus Scutellaria / I.B. Cole, F.T. Farooq and S.J. Murch -- Protocols for in vitro culture and phytochemical analysis of Phyllanthus species (Euphorbiaceae) / E. Catapan ... [et al.] -- In vitro clonal propagation of Asparagus racemosus, a high value medicinal plant / S. Saxena and N. Bopana -- Micropropagation of Penthorum chinense through axillary buds / J. Yang and Z.S. Peng -- Spontaneous plant regeneration and production of secondary metabolites from hairy root cultures of Centaurium erythraea Rafn / A. Subotic ... [et al.] -- Transgenic Hypericum perforatum / G. Franklin, M.M. Oliveira and A.C. Dias -- Agrobacterium-mediated transformation of Ruta graveolens L / K. Lievre ... [et al.] -- Gene expression profiling in Taxus baccata L. seedlings and cell cultures / K. Brun akova and J. Kosuth -- Catapol production in Chinese foxglove (Rehmannia glutinosa Libos.) hairy roots transformed with Agrobacterium rhizogenes ATCC15834 / S.J. Hwang -- Identification of medicinal plants and plant sequences: multiplexed MLPA assay / R.A. Barthelson -- Isolation of microsatellites from Catharanthus roseus (L.) G. Don using enriched libraries / S. Bhatia and B. Shokeen -- Production of cinnamyl glycosides in compact callus aggregate cultures of Rhodiola rosea through biotransformation of cinnamyl alcohol / Z. Gyorgy and A. Hohtola -- Spearmint plantlet culture system as a means to study secondary metabolism / B. Tisserat, M. Berhow and S.F. Vaughn -- Bioreactor production of secondary metabolites from cell cultures of periwinkle and sandalwood / J.V. Valluri -- Camptothecin production by in vitro cultures and plant regeneration in Ophiorrhiza species / T. Asano ... [et al.] -- Metabolomic analysis of Ocotea odorifera cell cultures: a model protocol for acquiring metabolite data / M. Maraschin ... [et al.] -- Production of 9-methoxycanthin-6-one from callus cultures of (Eurycoma longifolia Jack) Tongkat Ali / M. Maziah and N. Rosli -- Plant secondary metabolism in altered gravity / L.K. Tuominen, L.H. Levine and M.E. Musgrave -- The role of biotechnology in the production of the anticancer compound podophyllotoxin / H. Lata, C.S. Mizuno and R.M. Moraes.
  • 2013 Springer Protocols
    edited Maurizio Lambardi, Elif Aylin Ozudogru, Shri Mohan Jain.
    Micropropagation of pear (Pyrus sp.) / Barbara M. Reed [and others] -- In vitro propagation of jojoba / Berta E. Llorente and Nancy M. Apóstolo -- In vitro propagation of olive (Olea europaea L.) by nodal segmentation of elongated shoots / Maurizio Lambardi, Elif Aylin Ozudogru, and Romano Roncasaglia -- Micropropagation systems of feijoa (Acca sellowiana (O. Berg) burret) / Miguel Pedro Guerra [and others] -- Micropropagation of Vaccinium sp. by in vitro axillary shoot proliferation / Wojciech Litwinczuk -- In vitro propagation of peanut (Arachis hypogaea L.) by shoot tip culture / Elif Aylin Ozudogru, Ergun Kaya, and Maurizio Lambardi -- In vitro propagation of persimmon (Diospyros kaki Thunb.) / Edgardo Giordani, Mar Naval, and Carla Benelli -- Micropropagation of Citrus spp. by organogenesis and somatic embryogenesis / Benedetta Chiancone and Maria Antonietta Germanà -- Micropropagation of Prunus species relevant to cherry fruit production / Philippe Druart -- Micropropagation of peach rootstocks and cultivars / Ildikó Balla and Lucienne Mansvelt -- Micropropagation of Rubus and Ribes spp / Ewa Dziedzic and Joanna Jagła -- Somatic embryogenesis for efficient micropropagation of guava (Psidium guajava L.) / Nasim Akhtar -- Micropropagation of chokeberry by in vitro axillary shoot proliferation / Wojciech Litwińczuk -- Micropropagation of Lavandula spp / Sandra Gonçalves and Anabela Romano -- In vitro propagation of Acacia mangium and A. mangium? A. auriculiformis / Olivier Monteuuis, Antoine Galiana, and Doreen Goh -- In vitro propagation of ash (Fraxinus excelsior L.) by somatic embryogenesis / Maurizio Capuana -- Micropropagation of paradise tree (Melia azedarach) by in vitro culture of axillary buds / Luis A. Mroginski and Hebe Y. Rey -- In Vitro Propagation of Hydrangea spp / Barbara Ruffoni, Ermanno Sacco, and Marco Savona -- In vitro propagation of fraser photinia using Azospirillum-mediated root development / Berta E. Llorente and Ezequiel E. Larraburu -- Micropropagation of Helleborus through axillary budding / Margherita Beruto, Serena Viglione, and Alessandro Bisignano -- Micropropagation of Cordyline terminalis / Tui Ray, Prasenjit Saha, and Satyesh C. Roy -- Micropropagation of african violet (Saintpaulia ionantha Wendl.) / Mukund Shukla [and others] -- Micropropagation of Iris sp / Sladana Jevremovic, Zoran Jeknic, and Angelina Subotic -- Micropropagation of Gerbera (Gerbera jamesonii Bolus) / Ghani Minerva and Surinder Kumar -- Micropropagation of onion (Allium cepa L.) from immature inflorescences / Pablo Marinangeli -- In vitro propagation of cauliflower using curd microexplants / Martin Kieffer and Michael P. Fuller -- Micropropagation of Asparagus by in vitro shoot culture / Nataša Štajner -- Micropropagation and cryopreservation of garlic (Allium sativum L.) / E.R. Joachim Keller and Angelika Senula -- Micropropagation of globe artichoke (Cynara cardunculus L. var. scolymus) / Giovanni Iapichino -- In vitro rejuvenation of woody species / Paul E. Read and Christina M. Bavougian -- Encapsulation of in vitro- derived explants : an innovative tool for nurseries / Alvaro Standardi and Maurizio Micheli -- Thermotherapy, chemotherapy, and meristem culture in banana / Ludivine Lassois [and others] -- Agrobacterium-mediated genetic transformation of pineapple (Ananas comosus L., Merr.) / Minal Mhatre -- Protocol for inducing flower color somaclonal variation in Torenia (Torenia fournieri Lind.) / Duong Tan Nhut [and others] -- Production of pathogen-free horticultural crops by cryotherapy of in vitro-grown shoot tips / Chaohong Feng [and others].
  • 2006 Springer
    R. Bruening, A. Kuettner, T. Flohr, eds.
  • 2010 Springer Protocols
    edited by Laurie C. Doering.
    Neurosphere and Neural Colony-Forming Cell Assays / Sharon A. Louis, Brent A. Reynolds -- Directed Neuronal Differentiation of Embryonic and Adult-Derived Neurosphere Cells / Marcos R. Costa, Ravi Jagasia, Benedikt Berninger -- Culture and Differentiation of Human Neural Stem Cells / Soojung Shin, Mohan Vemuri -- Neural Differentiation of Human Embryonic Stem Cells / Mirella Dottori, Alice Pébay, Martin F. Pera -- Isolation and Culture of Primary Human CNS Neural Cells / Manon Blain, Veronique E. Miron, Caroline Lambert, Peter J. Darlington, Qiao-Ling Cui, Philippe Saikali, V. Wee Yong, Jack P. Antel -- Bioengineering Protocols for Neural Precursor Cell Expansion / Behnam A. Baghbaderani, Arindom Sen, Michael S. Kallos, Leo A. Behie -- Intracellular Calcium Assays in Dissociated Primary Cortical Neurons / Navjot Kaur, David V. Thompson, David Judd, David R. Piper, Richard G. Del Mastro -- Dissociated Hippocampal Cultures / Francine Nault, Paul Koninck -- Primary Sensory and Motor Neuron Cultures / Andrea M. Vincent, Eva L. Feldman -- Retinal Cell and Tissue Culture / Francisco L.A.F. Gomes, Michel Cayouette -- Preparation of Normal and Reactive Astrocyte Cultures / Jean Vellis, Cristina A. Ghiani, Ina B. Wanner, Ruth Cole -- Oligodendrocyte Progenitor Cell Culture / Akiko Nishiyama, Ryusuke Suzuki, Hao Zuo, Xiaoqin Zhu -- Isolation of Microglia Subpopulations / Makoto Sawada, Hiromi Suzuki -- Microglia from Progenitor Cells in Mouse Neopallium / Sergey Fedoroff, Arleen Richardson -- Primary Schwann Cell Cultures / Haesun A. Kim, Patrice Maurel -- Primary Dissociated Astrocyte and Neuron Co-culture / Shelley Jacobs, Laurie C. Doering -- Cerebellar Slice Cultures / Josef P. Kapfhammer -- Hippocampal Slice Cultures / Jesse E. Hanson, Adrienne L. Orr, Silvia Fernandez-Illescas, Ricardo A. Valenzuela, Daniel V. Madison -- Molecular Substrates for Growing Neurons in Culture / Saulius Satkauskas, Arnaud Muller, Morgane Roth, Dominique Bagnard -- Guidance and Outgrowth Assays for Embryonic Thalamic Axons / Alexandre Bonnin -- Detection of Cell Death in Neuronal Cultures / Sean P. Cregan -- Live Imaging of Neural Cell Functions / Sabine Bavamian, Eliana Scemes, Paolo Meda -- Tissue Culture Procedures and Tips / Arleen Richardson, Sergey Fedoroff.
  • 2006 Springer Protocols
    edited by Elena Hilario, John Mackay.
    Genomic DNA isolation from different biological materials / Duckchul Park -- Extraction of plant RNA / Elspeth MacRae -- Overview on hybridization and detection techniques / Elena Hilario -- Checkerboard DNA/DNA hybridization technology : using DIG detection / Lisa S. Gellen, Glenn Wall-Manning, and Chris H. Sissons -- Nonradioactive northern and southern analyses from plant samples / Christoph Peterhaensel, Dagmar Weier, and Thomas Lahaye -- Screening a BAC library with nonradioactive overlapping oligonucleotide (overgo) probes / Elena Hilario, Tiffany F. Bennell, and Erik Rikkerink -- Direct in-gel hybridization of DNA with digoxigenin-labeled probes / Saeed A. Khan and Mohamed S. Nawaz -- In situ hybridization of termite microbes / Shigeharu Moriya ... [et al.] -- RNA electrophoretic mobility shift assay using a fluorescent DNA sequencer / Yukinori Eguchi -- Comparative quantitation of mRNA expression in the central nervous system using fluorescence in situ hybridization / Darren J. Day, Eli M. Mrkusich, and John H. Miller -- Visualization of gene expression by fluorescent multiplex real-time PCR amplification / Maria Rosa Ponce ... [et al.] -- Fluorescence in situ hybridization for the identification of environmental microbes / Annelie Pernthaler and Jakob Pernthaler -- Introduction to kinetic (real-time) PCR / John Mackay -- Validation of siRNA knockdowns by quantitative real-time PCR / Sukru Tuzmen -- Real-time quantitative PCR as an alternative to southern blot or fluorescence in situ hybridization for detection -- Of gene-copy number changes / Jasmien Hoebeeck, Frank Speleman, and Jo Vandesompele -- Design and work-up of a new molecular diagnostic assay based on real-time PCR / Harald Kessler -- Real-time PCR fluorescent chemistries / John Mackay and Olfert Landt -- Microarrays : an overview / Norman H. Lee and Alexander I. Saeed -- Oligonucleotide microarrays for the study of coastal microbial communities / Gaspar Taroncher-Oldenburg and Bess B. Ward.
  • 2015 Springer Protocols
    edited by Mathieu Vinken, Vera Rogiers.
    Isolation and culture of mouse hepatocytes -- Cryopreservation of hepatocytes -- Culture conditions promoting proliferation and cell cycle synchronization -- Immortalized human hepatic cell lines for In vitro testing and research purposes -- Culture and functional characterization of human hepatoma hepG2s -- Establishment and characterization of an in vitro model of Fas-mediated hepatocyte cell death -- Serum-free directed differentiation of human embryonic stem cells to hepatocytes -- Human skin-derived precursor Cells: isolation, expansion, and hepatic differentiation -- Generation of hepatocytes from pluripotent stem cells for drug screening and developmental modeling -- Differentiation-promoting medium additives for hepatocyte -- Cultivation and cryopreservation -- Coculture and long-term maintenance of hepatocytes -- Primary hepatocytes in sandwich culture -- Establishing liver bioreactors for In Vitro Research -- Epigenetic modifications as antidedifferentiation strategy for primary hepatocytes in culture -- Transfection of Primary Hepatocytes with Liver-enriched transcription factors using adenoviral vectors -- Transcriptomics of hepatocytes treated with Toxicants for Investigating Molecular mechanisms underlying hepatotoxicity -- Global microRNA analysis in primary hepatocyte Cultures -- Mass Spectrometry-Based proteomics for telative protein quantification and biomarker Identification in primary human Hepatocytes -- Targeted metabolomics for homocysteine-related metabolites in primary hepatocytes -- Measurement of cytochrome P450 Enzyme Induction and Inhibition in human hepatoma cells -- Analysis of sinusoidal drug uptake transporter activities in Primary Human Hepatocytes -- Measurement of albumin secretion as functionality test in primary hepatocyte cultures -- Measurembent of Blood Coagulation Factor Synthesis in cultures of human hepatocytes -- Functionality testing of primary hepatocytes in Culture by Measuring Urea Synthesis -- Assay of Bile acid conjugation and excretion in human hepatocytes -- General cytotoxicity assessment by Means of the MTT assay -- Measurement of apoptotic and necrotic cell death in primary hepatocyte cultures -- Critical factors in the Assessment of cholestatic liver injury In vitro -- In vitro cell culture models of hepatic steatosis -- Assessment of liver fibrotic Insults In Vitro.
  • 2013 CRCnetBASE
    editors, C-M Charlie Ma, Tony Lomax.
    "Preface: This book aims at providing a comprehensive and practical guide to proton and carbon ion therapy for a broad range of personnel in medical physics and radiation therapy, including medical physicists, radiation oncologists, dosimetrists, therapists, medical engineers, and trainees in these disciplines. The scope of this book includes physics and radiobiology basics of proton and ion beams, dosimetry methods and radiation measurements, treatment delivery systems, and practical guidance on patient setup, target localization, and treatment planning for clinical proton and carbon ion therapy, as well as detailed reports on the treatment of pediatric cancers, lymphomas, and various other cancers. The aim is to offer a balanced and critical assessment of the state-of-the-art proton and carbon ion therapy along with the discussion of major challenges and future outlook. This book contains 11 chapters. The first chapter provides an overview, and the final chapter describes future challenges. The remaining content is divided into three sections. The first section provides the basic aspects of proton and carbon ion therapy equipment covering accelerators, gantries, and delivery systems. Chapter 2 describes accelerators for proton and carbon ion therapy, including cyclotron, synchrotron, and other acceleration developments (such as dielectric wall accelerator, laser accelerated particle beams, and new concepts, including the cyclinac and compact cyclotron solutions). Chapter 3 describes proton and carbon ion therapy systems, with a focus on their major components, including energy selection systems, beam transport systems, control systems, gantries, and beam delivery systems"--Provided by publisher.
  • 2013 Springer
    Santosh Yajnik.
    While radiation therapy is a mainstay of cancer treatment, traditional linear accelerators mainly use photons to irradiate cancerous tissue. Photons deposit much more energy in the surrounding normal tissue than protons. Proton beam therapy is a revolutionary alternative that deposits most of its cancer-killing energy within the area of the tumor, thereby potentially improving cure rates and reducing side effects in properly selected patients. This book guides the reader through existing evidence supporting proton beam therapy for an increasing number of patients and conditions, including pediatric, prostate, and lung cancer, mediastinal tumors, skull base tumors, conditions of the eye, and sarcomas.
  • 2013 Karger
    volume editors, Tsutomu Chiba, Peter Malfertheiner, Hiroshi Satoh.
    Discovery and Development of Proton Pump Inhibitors / Satoh, H. (Kyoto) -- Pharmacokinetics, Pharmacodynamics, and Pharmacogenetics of Proton Pump Inhibitors / Furuta, T.; Sugimoto, M.; Shirai, N. (Hamamatsu) -- Proton Pump Inhibitors in Gastroesophageal Reflux Disease / Bruley des Varannes, S. (Nantes) -- Proton Pump Inhibitors in Gastroprotection: Prevention and Healing of Nonsteroidal Anti-Inflammatory Drug-, Aspirin-, and Cyclooxygenase-2 Inhibitor-Induced Gastroduodenal Lesions / Kyaw, M.H.; Chan, F.K.L. (Hong Kong) -- Proton Pump Inhibitors: Key Ingredients in Helicobacter pylori Eradication Treatment / Sugiyama, T. (Toyama City) -- Proton Pump Inhibitor Management in Bleeding Peptic Ulcer Disease / Sung, J. (Hong Kong) -- Proton Pump Inhibitors in Functional Dyspepsia / Miwa, H. (Nishinomiya) -- Role of Acid Suppression in Exocrine Pancreatic Insufficiency: A Therapeutic Principle / Waldthaler, A.; Schütte, K.; Malfertheiner, P. (Magdeburg) -- Proton Pump Inhibitors and Gastrointestinal Side Effects / Nakamura, S. (Fukuoka); Seno, H.; Chiba, T. (Kyoto) -- Administration of Proton Pump Inhibitors and Risk of Systemic Side Effects / Kinoshita, Y.; Ishihara, S. (Izumo).
  • 2012 CRCnetBASE
    edited by Harald Paganetti.
    "Compared to x-ray-based radiotherapeutic modalities, proton therapy provides greater 3D localization, higher beam doses, access to deeper tumors, and less damage to surrounding healthy tissue. Though over fifty years old, it is now coming to the forefront of cancer treatment with greater understanding of the biophysics and better treatment and patient outcomes. This text presents an overview of proton therapy that addresses all key topics including, biophysics, accelerators, hardware, beam delivery, treatment planning, dose calculation, quality assurance, and precision. Features (1) Provides an overview of proton therapy; (2) Covers beam delivery using passive scattering and magnetic beam scanning; (3) Details the physics of treatment planning for homogenous fields and intensity-modulated fields; and (4) Discusses precision and uncertainties for both moving and non-moving targets"--Provided by publisher.
  • 2015 Springer
    Lynn A. Crosby, Robert J. Neviaser, editors.
    Proximal Humerus Fractures includes everything the orthopedic surgeon needs to know about the clinical management of these common shoulder injuries. Although non-operative treatment techniques are addressed and can be used in less severe circumstances, this book focuses mainly on the current operative treatment techniques for proximal humerus and tuberosity fractures, malunions and nonunions, including open reduction, percutaneous pinning, locking plate and intramedullary nail fixation, and humeral head hemiarthroplasty and reverse shoulder arthroplasty. A chapter on complications associated with these types of fractures and their management is also included. Dedicated to a common musculoskeletal injury, especially in athletes and the elderly suffering from osteoporosis, Proximal Humerus Fractures will be a valuable resource to all orthopedic surgeons and practitioners of sports medicine.
  • 2010 Springer
    Laurent Misery, Sonja Ständer, editors.
    Part 1. Neurophysiology -- Neuroanatomy of Itch / Akihiko Ikoma -- Neuroreceptors and Neuromediators / Sonja Ständer and Thomas A. Luger -- The Brain in the Skin: Neuro-Epidermal Synapses / Nicholas Boulais and Laurent Misery -- Central Transmission: From Skin to Brain / Tejesh Surendra Patel and Gil Yosipovitch -- Modulation of Pruritus: Peripheral and Central Sensitisation / Martin Schmelz -- Interaction of Pruritus and Pain / Martin Schmelz -- Neuroimaging / Florian Pfab, Michael Valet, Thomas Tölle, Heidrun Behrendt and Johannes Ring, et al. -- Measurement of Itch / Joanna Wallengren -- Experimental Models of Itch / Ulysse Pereira and Laurent Misery -- Part 2. Clinics -- Pruritus, Pain and Other Abnormal Skin Sensations / Laurent Misery -- The Epidemiology of Pruritus / Florence Dalgard and Elke Weisshaar -- Classification / Sonja Ständer -- Examination of Patients / Elke Weisshaar -- Inflammatory Diseases / Jacek C. Szepietowski and Adam Reich -- Pruritus in Autoimmune Diseases / Yozo Ishiuji and Alan B. Fleischer -- Urticaria / Ulrike Raap, Alexander Kapp and Bettina Wedi -- Pruritic Skin Diseases in Travellers / Eric Caumes -- Pruritus in Cutaneous T-cell Lymphoma / Tobias Görge and Meinhard Schiller -- Anal Pruritus / Sylvia Proske and Wolfgang Hartschuh -- Secondary Reactive Conditions in Pruritic Skin / Joanna Wallengren -- Aquadynia and Aquagenic Pruritus / Laurent Misery -- Sensitive Skin / Laurent Misery and Sonja Ständer -- Neurogenic Pruritus with Cerebral and/or Medullary Abnormalities / Camille Fleuret and Laurent Misery -- Localized Neuropathic Pruritus / Martin Marziniak, Esther Pogatzki-Zahn and Stefan Evers -- Brachioradial Pruritus / Martin Marziniak and Sonja Ständer -- Other Neurological Causes of Itch / Martin Marziniak, Esther Pogatzki-Zahn and Stefan Evers -- Chronic Kidney Disease-Associated Pruritus / Thomas Mettang -- Pruritus in Patients with Hepatobiliary Diseases / Andreas E. Kremer, Ronald P. J. Oude-Elferink and Ulrich Beuers -- Endocrine Diseases / Elke Weisshaar -- Pruritus in the Course of Malignancy / Zbigniew Zylicz and Malgorzata Krajnik -- Drugs / Jacek C. Szepietowski and Adam Reich -- Interaction Between Pruritus and Stress or Other Psychosomatic Factors / Laurent Misery -- Psychosomatic Aspects and Psychiatric Conditions / Gudrun Schneider -- Psychosomatics and Psychiatry, Psychological Approach / Sabine Dutray and Laurent Misery -- Psychogenic Pruritus / Laurent Misery -- Pruritus in Children / Matthieu Gréco and Laurent Misery -- Pruritus Vulvae / Micheline Moyal-Barracco -- Part 3. Treatment -- General Principles and Guidelines / Elke Weisshaar -- Menthol / Laurent Misery and Sonja Ständer -- Capsaicin / Laurent Misery -- Topical Immunomodulators / Laurent Misery -- Cannabinoid-Receptor Agonists / Sonja Ständer -- Other Topical Treatments / Laurent Misery -- Antihistamines / Caroline Gaudy-Marqueste -- Anticonvulsants for the Treatment of Pruritus / Nora V. Bergasa and Deewan Deewan -- Opioid Receptor Antagonists or Agonists / Laurent Misery -- Serotonin Reuptake Inhibitors and Other Antidepressants in the Treatment of Chronic Pruritus / Zbigniew Zylicz and Małgorzata Krajnik -- Systemic Immunosuppressants in the Treatment of Pruritus / Silvia Moretti, Francesca Prignano and Torello Lotti -- Other Systemic Treatments / Sonja Ständer -- Psychological Intervention / Sabine Dutray and Laurent Misery -- Ultraviolet Phototherapy of Pruritus / Joanna Wallengren -- Itch and Acupuncture / Laurent Misery and Laurence Potin-Richard -- Future Perspectives: Outlook / Sonja Ständer and Laurent Misery.
  • 2014 Springer Protocols
    edited by Laura Poliseno.
    Pseudogene redux with new biological significance / Leonardo Salmena -- Contribution of pseudogenes to sequence diversity / Mauno Vihinen -- Computational methods for pseudogene annotation based on sequence homology / Paul M. Harrison -- Computational methods of identification of pseudogenes based on functionality : entropy and GC content / Evgeniy S. Balakirev ... [et al.] -- Methods of identification of pseudogenes based on functionality : hybridization of 18S rRNA and mRNA during translation / Chuanhua Xing -- Whole-genome identification of neutrally evolving pseudogenes using the evolutionary measure dN/dS / Lise Olivia Andrieux and David Torrents Arenales -- Methods to study the occurrence and the evolution of pseudogenes through a phylogenetic approach / Jacques Dainat and Pierre Pontarotti -- Methods for detecting transcribed pseudogenes : PCR on regions of high sequence similarity followed by cloning and sequencing / Wenyong Ding and Jianwu Dai -- RNA amplification for pseudogene detection using RNA-Seq / Stephen C. M. Tsoi and Michael K. Dyck -- GENCODE pseudogenes / Adam Frankish and Jennifer Harrow -- Methods to detect transcribed pseudogenes : RNA-Seq discovery allows learning through features / Camilo Valdes and Enrico Capobianco -- Proteomics techniques for the detection of translated pseudogenes / Nadia Ucciferri and Silvia Rocchiccioli -- Pseudogenes as competitive endogenous RNAs : target prediction and validation / Florian A. Karreth ... [et al.] -- Pseudogenes : a novel source of trans-acting antisense RNAs / Per Johnsson, Kevin V. Morris, and Dan Grandér -- Pseudogene-derived endogenous siRNAs and their function / Wen-Ling Chan and Jan-Gowth Chang -- Methods to study translated pseudogenes : in vitro translation, fusion with a tag/reporter gene, and complementation assay / Anne Parle-McDermott
  • 2014 Springer Protocols
    edited by Alain Filloux, Juan-Luis Ramos.
    Gene transfer : transduction / Emanuela Frangipani -- Gene transfer : transformation/electroporation / Frédéric Cadoret, Chantal Soscia, and Romé Voulhoux -- Gene transfer : conjugation / Thibault G. Sana, Aurélie Laubier, and Sophie Bleves -- Pseudomonas bacteriophage isolation and production / Joana Azeredo, Sanna Sillankorva, and Diana P. Pires -- Genotyping methods / Burkhard Tümmler -- Drug susceptibility testing by dilution methods / Katy Jeannot and Patrick Plésiat -- Plate-based assay for swimming motility in Pseudomonas aeruginosa / Dae-Gon Ha, Sherry L. Kuchma, and George A. O'Toole -- Plate-based assay for swarming motility in Pseudomonas aeruginosa / Dae-Gon Ha, Sherry L. Kuchma, and George A. O'Toole -- Motility assay : twitching motility / Lynne Turnbull and Cynthia B. Whitchurch -- Qualitative and quantitative assays for flagellum- mediated chemotaxis / José Antonio Reyes Darias [and five others] -- Microscopic analysis : morphotypes and cellular appendages / Olga Zaborina, John Alverdy, Megha Shah, and Yimei Chen -- Determination of lipolytic enzyme activities / Karl-Erich Jaeger and Filip Kovacic -- Elastinolytic and proteolytic enzymes / Efrat Kessler and Mary Safrin -- In vitro assays to monitor the activity of Pseudomonas aeruginosa type III secreted proteins / Stephanie L. Rolsma and Dara W. Frank -- Cell fractionation / Bérengère Ize, Véronique Viarre, and Romé Voulhoux -- Characterization of molecular interactions using isothermal titration calorimetry / Tino Krell [and seven others] -- Proteomic analysis / Pascal Cosette and Thierry Jouenne -- Membrane proteomics of Pseudomonas aeruginosa / Zofia Magnowska, Isabel Hartmann, Lothar Jänsch, and Dieter Jahn -- Construction of Pseudomonas aeruginosa two-hybrid libraries for high-throughput assays / Sophie de Bentzmann and Christophe Bordi -- Biosensors for qualitative and semiquantitative analysis of quorum sensing signal molecules / Matthew Fletcher [and tree others] -- LC-MS/MS quantitative analysis of quorum sensing signal molecules / Catharine A. Ortori [and four others] -- LC/MS/MS-based quantitative assay for the secondary messenger molecule, c-di-GMP / Yasuhiko Irie and Matthew R. Parsek -- Metabolic footprinting : extracellular metabolomic analysis / Volker Behrends, Huw D. Williams, and Jacob G. Bundy -- Pyoverdine and pochelin measurements / Françoise Hoegy, Gaetan L. A. Mislin, and Isabelle J. Schalk -- Measurement of phenazines in bacterial cultures / Suzanne E. Kern and Dianne K. Newman -- Extraction and measurement of NAD(P)+ and NAD(P)H / Suzanne E. Kern, Alexa Price-Whelan, and Dianne K. Newman -- Cyanide measurements in bacterial culture and sputum / Chandrika Goh Nair, Ben Ryall, and Huw D. Williams -- Monitoring iron uptake by siderophores / Françoise Hoegy and Isabelle J. Schalk -- Exopolysaccharide quantification / Irina Sadovskaya -- Liquid chromatography/mass spectrometry for the identification and quantification of rhamnolipids / Ahmad Mohammad Abdel-Mawgoud, François Lépine, and Eric Déziel -- LPS quantitation procedures / Joseph S. Lam, Erin M. Anderson, and Youai Hao -- Monitoring lectin interactions with carbohydrates / Sophie de Bentzmann, Annabelle Varrot, and Anne Imberty -- Mining the Pseudomonas genome / Geoffrey L. Winsor and Fiona S. L. Brinkman -- Identification of bacterial small RNAs by RNA sequencing / María Gómez-Lozano [and three others.] -- Gene amplification and qRT-PCR / Cerith Jones and Alain Filloux -- The Standard European Vector Architecture (SEVA) plasmid toolkit / Gonzalo Durante-Rodríguez, Víctor de Lorenzo, and Esteban Martínez-García -- Chromosomal integration of transcriptional fusions / Rafael Silva-Rocha and Víctor de Lorenzo -- A method to capture large DNA fragments from genomic DNA / Geneviève Ball, Alain Filloux, and Romé Voulhoux -- Transposon mutagenesis / Hemantha D. Kulasekara -- Site-directed mutagenesis and gene deletion using reverse genetics / Daniela Muhl and Alain Filloux -- Signature-tagged mutagenesis / Irena Kukavica-Ibrulj and Roger C. Levesque -- Construction of a Pseudomonas aeruginosa genomic DNA library / Christophe Bordi -- Strategy for genome sequencing analysis and assembly for comparative genomics of Pseudomonas genomes / Julie Jeukens [and three others] -- Promoter fusions with optical outputs in individual cells and in populations / Ilaria Benedetti and Victor de Lorenzo -- Chromatin immunoprecipitation for ChIP-chip and ChIP-seq / Sebastian Schulz and Susanne Häussler -- Transcriptional analysis of Pseudomonas aeruginosa infected Caenorhabditis elegans / Ashleigh MacKenzie [and three others] -- Methods for studying biofilm formation : flow cells and confocal laser scanning microscopy / Tim Tolker-Nielsen and Claus Sternberg -- Biofilm formation in the 96-well microtiter plate / Barbara M. Coffey and Gregory G. Anderson -- Methods for studying biofilm dispersal in Pseudomonas aeruginosa / Nicolas Barraud [and three others] -- Pseudomonas aeruginosa PA14 pathogenesis in Caenorhabditis elegans / Natalia V. Kirienko [and three others] -- Assessing Pseudomonas aeruginosa virulence using a nonmammalian host : Dictyostelium discoideum / Geneviève Filion and Steve J. Charette -- Assessing Pseudomonas virulence with nonmammalian host : Galleria mellonella / Gudrun Koch [and three others] -- Assessing Pseudomonas virulence with the nonmammalian host model : Arabidopsis thaliana / Regina L. Baldini, Melissa Starkey, and Laurence G. Rahme -- Assessing Pseudomonas aeruginosa persister/antibiotic tolerant cells / Ronen Hazan [and three others] -- Assessing Pseudomonas virulence with nonmammalian host : Zebrafish / María A. Llamas and Astrid M. van der Sar -- Assessing Pseudomonas virulence with a nonmammalian host : Drosophila melanogaster / Samantha Haller, Stefanie Limmer, and Dominique Ferrandon -- Assessing Pseudomonas virulence using host cells / Iwona Bucior, Cindy Tran, and Joanne Engel -- Assessing Pseudomonas aeruginosa virulence and the host response using murine models of acute and chronic lung infection / Irena Kukavica-Ibrulj [and four others] -- Assessing Pseudomonas virulence using mammalian models : acute infection model / Antje Munder and Burkhard Tümmler -- Burn mouse models / Henrik Calum, Niels Høiby, and Claus Moser.
  • 2008 Springer
    edited by M'Barek Fatmi ... [et al.].
  • 2010 Springer
    Juan-Luis Ramos, Alain Filloux, editors.
    Part I. Regulation and Control of Virulence -- 1. Small RNAs of Pseudomonas spp. / Elisabeth Sonnleitner, Nicolas González and Dieter Haas -- 2. 2-Alkyl-4(1H)-Quinolone Signalling in Pseudomonas aeruginosa / Matthew P. Fletcher, Stephan Heeb, Siri Ram Chhabra, Stephen P. Diggle, Paul Williams, and Miguel Cámara -- 3. Cell-Surface Signalling in Pseudomonas / María A. Llamas and Wilbert Bitter -- 4. Second Messenger c-di-GMP Signaling in Pseudomonas aeruginosa / Massimo Merighi and Steve Lory -- Part II. Life Styles -- 5. Emergence of Pseudomonas aeruginosa in Cystic Fibrosis Lung Infections / Joanna B. Goldberg -- 6. Insights into the Life Styles of Pseudomonas stutzeri / Elena García-Valdés, Magdalena Mulet, and Jorge Lalucat -- Part III. Physiology, Metabolism and Markers -- 7. Pyoverdine Siderophores as Taxonomic and Phylogenic Markers / Jean-Marie Meyer -- 8. Metabolism of Acyclic Terpenes by Pseudomonas / Jesús Campos-García -- 9. Heavy Metal Resistance in Pseudomonads / Esther Aguilar-Barajas, Martha I. Ramírez-Díaz, Héctor Riveros-Rosas, and Carlos Cervantes.
  • 2005 Springer
    Kenneth B. Gordon, Eric M. Ruderman, editors.
    Also available: Print – 2005
  • 2016 Springer
    Adewale Adebajo, Wolf-Henning Boehncke, Dafna D. Gladman, Philip J. Mease, editors.
    Section 1. Historical Aspects -- 1. Historical Perspectives on Psoriatic Arthritis -- 2. GRAPPA Historical Perspective -- Section 2. Epidemiological Aspects -- 3. Classification Criteria for Psoriasis and Psoriatic Arthritis -- 4. Epidemiology of Psoriasis and Psoriatic Arthritis -- 5. The Natural History of Psoriatic Arthritis -- Section 3. Pathological and Genetic Aspects -- 6. Immunopathogenesis of Psoriasis Skin and Nail -- 7. Immunopathology of the Psoriatic Arthritis Musculoskeletal Lesions -- 8. Innate and Acquired Cellular Immune Responses in Psoriasis and Psoriatic Arthritis -- 9. Cytokine Pathways in Psoriasis and Psoriatic Arthritis -- 10. Genetics of Psoriasis -- 11. Update on the Genetics of Psoriatic Arthritis -- 12. Animal Models of Psoriasis and PSoriatic Arthritis -- 13. Mechanisms of Bone Remodelling in Psoriatic Arthritis -- Section 4. Clinical Aspects -- 14. Psoriasis -- 15. Scalp Psoriasis: Clinical Features and Assessment -- 16. Nail Psoriasis: Clinical Features and Assessment -- 17. Psoriatic Arthritis -- Section 5. Imaging -- 18. Imaging Tools in Skin and Nail Psoriasis -- 19. Radiographic Assessment of Psoriatic Arthritis (PsA) -- 20. Psoriasis and Psoriatic Arthritis: Ultrasound Applications -- 21. Magnetic Resonance Imaging in Psoriatic Arthritis -- 22. Future Trends in Imaging Modalities for Psoriasis and Psoriatic Arthritis -- Section 6. Laboratory Tests -- 23. Relevant Laboratory Tests and Therapeutic Monitoring in Psoriasis -- 24. Laboratory Tests for Psoriatic Arthritis. Section 7. Management Aspects -- 25. Paradigms of Treatment in PsA -- 26. Topical and Systemic Therapies for Moderate-to-severe Psoriasis.-27. Oral Non-Biologic Therapies and Non-Pharmacological Therapies in PsA -- 28. Biologic Therapy for Psoriasis -- 29. Biologic Therapy of Psoriatic Arthritis.
  • 2016 Cambridge
    edited by Colin Hemmings, BSc, MBBS, MSc, MA, MD(Res), MRCPsych, Maudsley Hospital, London, UK, Nick Bouras, MD, PhD, FRCPsych, Institute of Psychiatry, Psychology and Neuroscience, King's College London, and Maudsley International, London, UK.
    Section I. Foundations --Historical and international perspectives of services -- Classification and diagnosis -- The epidemiology of psychiatric disorders in adults with intellectual disabilities -- Assessment instruments and rating scales -- Section 2. Mental disorders -- Dementias --Schizophrenia spectrum disorders -- Mood disorders -- Anxiety disorders -- Stress, traumatic, and bereavement reactions -- Personality disorders -- Mental illness with intellectual disabilities and autism spectrum disorders -- Attention-deficit/hyperactivity disorder (ADHD) -- Section 3. Interventions -- Psychopharmacology -- Psychodynamic psychotherapy -- Cognitive-behavioral therapy -- Behavioral approaches -- Section 4. Special topics -- Psychopathology of children with intellectual disabilities -- Behavioral phenotypes/genetic syndromes -- Offending behavior -- Problem behaviors and the interface with psychiatric disorders -- The interface between medical and psychiatric disorders -- Epilepsy -- Section 5. Services -- Specialized and mainstream mental health services -- Service users' and carers' experiences of mental health services -- Carer and family perspectives -- Section 6. Reflections -- Reflections.
  • 2006 Ovid
    [edited by] Francisco Fernandez, Pedro Ruiz.
    Epidemiology / Margarita Alegría ... [et al.] -- Virology, immunology, transmission, and disease stage / Karl Goodkin -- Medical treatment and occupational exposure / Ellen A.B. Morrison, Jon A. Levenso -- Psychiatric assessment / María Fernanda Gómez, Mary Alice O'Dowd -- Psychological and neuropsychological testing / Joel K. Levy -- Electrophysiology and brain mapping / Harold W. Goforth, Lukasz M. Konopka -- Psychological reactions / Vicenzio Holder-Perkins, Jeffrey S. Akman -- Stress-distress spectrum and adjustment disorders / Dimitri D. Markov, Elisabeth J.S. Kunkel, Howard Field -- Anxiety disorders / Annette M. Matthews, Manuel Trujillo -- Mood disorders / Pedro Ruiz -- Personality disorders / Khenu Singh, Herb Ochitill -- Cognitive disorders / Angela M. McBride, Francisco Fernandez -- Psychotic disorders / Ewald Horwath, Francine Cournos -- Substance use disorders / Stephen J. Ferrando, Steven L. Batki -- Sleep disorders / Carlos A. Santana, Francisco Fernandez -- Psychotropic drug interactions with antiretroviral medications / Philip A. Bialer, Kyle S. Kato, Vassilios Latoussakis -- Pain syndromes / William Breitbart -- Sexually transmitted infections / Angela L. Stotts ... [et al.] -- Psychiatric comorbidities in medically ill patients with HIV/AIDS / Stephen J. Ferrando, Constantine G. Lyketsos -- HIV/AIDS among Hispanic Americans / Pedro Ruiz, Frank Fernandez -- HIV/AIDS among African Americans / William B. Lawson, Janice G. Hutchinson, Dianne L. Reynolds -- HIV/AIDS among Asian and Pacific Islander Americans / Lynette J. Menezes, Todd Wills, Karina D'Souza -- HIV/AIDS among American Indians and Alaska natives / Carol E. Kaufman ... [et al.] -- HIV/AIDS among neonates and infant / Andrea Stolar, Johanna Goldfarb -- HIV/AIDS among children and adolescents / Andres J. Pumariega, Margaret A. Shugart, JoAnne B. Pumariega -- HIV/AIDS among older adults / Maria D. Llorente, Julie E. Malphurs -- HIV/AIDS among women / Isabel T. Lagomasino, Gustavo Rodriguez -- HIV/AIDS among men who have sex with men / Milton L. Wainberg, Kenneth B. Ashley -- HIV/AIDS among women who have sex with women / Alison R. Jones, Cynthia L. Hoyler -- HIV/AIDS among the homeless / Jacqueline Maus Feldman, Stephen M. Goldfinger -- HIV/AIDS among prisoners / Wade C. Myers ... [et al.] -- HIV/AIDS and the patient's family / James L. Griffith, Michael Golder -- Ethical, forensic, and legal considerations / James Satriano -- Religious and spiritual considerations / Daniel W. Hicks, Francis G. Lu -- Psychotherapeutic strategies / Claire Zilber -- Complementary and holistic medicine / Janet Konefal, Jessica Lillisand -- Biopsychosocial aspects / Cheryl Gore-Felton, Cheryl Koopman, David Spiegel -- Suicide and end-of-life care / Mary Ann Cohen -- Prevention and education strategies / Michael D. Knox, Tiffany Chenneville -- Physician assisted suicide and voluntary euthanasia / Marshall Forstein.
  • 2007.
    by Abdel-Kareem Chehadi, Northern Ontario School of Medicine, Laurentian University.
  • 2012 Springer Protocols
    edited by Firas H. Kobeissy.
    New frontiers in animal research of psychiatric illness / Arie Kaffman and John J. Krystal -- Experimental psychiatric illness and drug abuse models : from human to animal, an overview / Scott Edwards and George F. Koob -- Qualitative versus quantitative methods in psychiatric research / Mahdi Razafsha [and others] -- Animal models of self-injurious behaviour : an overview / Darragh P. Devine -- Rodent models of adaptive decision making / Alicia Izquierdo and Annabelle M. Belcher -- Animal models of depression and neuroplasticity : assessing drug action in relation to behavior and neurogenesis / Ying Xu [and others] -- Modeling depression in animal models / David H. Overstreet -- Behavioral model for assessing cognitive decline / Michael Guidi and Thomas C. Foster -- The pemoline model of self-injurious behaviour / Darraugh P. Devine -- Modeling risky decision making in rodents / Nicholas W. Simon and Barry Setlow -- Open space anxiety test in rodents : the elevated platform with steep slopes / Abdelkader Ennaceur -- An animal model to study the molecular basis of tardive dyskinesia / Mahendra Bishnoi and Ravneet K. Boparai -- Models of chronic alcohol exposure and dependence / darin J. Knapp and George R. Breese -- Rat models of prenatal and adolescent cannabis exposure / Jennifer A. DiNieri and Yasmin L. Hurd -- Modeling nicotine addiction in rats / Stephanie Caille [and others] -- Animal models of nicotine withdrawal : intracranial self-stimulation and somatic signs of withdrawal / Rayna M. Bauzo and Adrie W. Bruijnzeel -- Methods in drug abuse models : comparison of different models of methamphetamine paradigms / Firas H. Kobeissy [and others] -- Cocaine self-administration in rats : hold-down procedures / Benjamin A. Zimmer and David C.S. Roberts -- Cocaine self-administration in rats : discrete trials procedures / Carson V. Dobrin and David C.S. Roberts -- Cocaine self-administration in rats : threshold procedures / Erik B. Oleson and David C.S. Roberts -- Assessing locomotor-stimulating effects of cocaine in rodents / Drake Morgan [and others] -- Methods in tobacco abuse : proteomic changes following second-hand smoke exposure / Joy Guingab-Cagmat [and others] -- Animal models of sugar and fat bingeing : relationship to food addiction and increased body weight / Nicole M. Avena, Miriam E. Bocarsly, and Bartley G. Hoebel -- Animal models of overeating / Neil E. Rowland -- The activity-based anorexia mouse model / Stephanie J. Klenotich and Stephanie C. Dulawa -- Dissociating behavioral, autonomic, and neuroendocrine effects of androgen steroids in animal models / Amy S. Kohtz and Cheryl A. Frye -- Interleukin-2 and the septohippocampal system : intrinsic actions and autoimmune processes relevant to neuropsychiatric disorders / John M. Petitto [and others] -- Experimental schizophrenia models in rodents established with inflammatory agents and cytokines / Hiroyuki Nawa and Kiyofumi Yamada -- P11 : a potential biomarker for posttraumatic stress disorder / Lei Zhang, Robert J. Ursano, and He Li -- Investigation of age-specific behavioral and proteomic changes in an animal model of chronic ethanol exposure / Antoinette M. Maldonado-Devincci, Stanley M. Stevens Jr., and Cheryl L. Kirstein -- Quantitative peptidomics to measure neuropeptide levels in animal models relevant to psychiatric disorders / Julia S. Gelman [and others] -- ADHD animal model characterization : transcriptomics and proteomics analyses / Yoshinori Masuo, Junko Shibato, and Randeep Rakwal -- Psychiatric disorder biomarker discovery using quantitative proteomics / Michaela D. Filiou and Christoph W. Turck -- Gene profiling of laser-microdissected brain regions and individual cells in drug abuse and schizophrenia research / Pietro Paolo Sanna, Vez Repunte-Canonigo, and Alessandro Guidotti -- Stable isotope labeling with amino acids in cell culture-based proteomic analysis of ethanol-induced protein expression profiles in microglia / Bin Liu, David S. Barber, and Stanley M. Stevens Jr. -- Systems biology in psychiatric research : from complex data sets over wiring diagrams to computer simulations / Felix Tretter and Peter J. Gebicke-Haerter -- Data mining in psychiatric research / Diego Tovar [and others].
  • 2006
    edited by Victoria Hendrick.
    Status: Not Checked OutLane Catalog Record
    Bipolar disorder: special issues in pregnancy and the postpartum / Lori L. Altshuler and Carol Kiriakos -- Schizophrenia during pregnancy and the postpartum period / Mary V. Seeman -- Pregnancy and substance abuse / Karen A. Miotto ... [et al.] -- Eating disorders in pregnancy and the postpartum: empirically informed treatment guidelines / Debra L. Franko -- Children of parents with mental illness: outcomes and interventions / Mary F. Brunette and Teresa Jacobsen. General considerations in treating psychiatric disorders during pregnancy and following delivery / Victoria Hendrick -- Prevalence, clinical course, and management of depression during pregnancy / Sanjog Kalra and Adrienne Einarson -- Postpartum depression: a common complication of childbirth / C. Neill Epperson and Jennifer Ballew -- Treatment of anxiety disorders in pregnancy and the postpartum / Jonathan S. Abramowitz, Karin Larsen, and Katherine M. Moore --
  • 2014 Springer
    Manfred Gerlach, Andreas Warnke, Laurence Greenhill, editors.
    This book offers a comprehensive survey of the current state of knowledge in the field of neuro-psychopharmacology in childhood and adolescence. In the first part, the essentials of neuro-psychopharmacology are presented in order to provide a deeper understanding of the principles and particularities in the pharmacotherapy of children and adolescents. This part includes information on neurotransmitters and signal transduction pathways, molecular brain structures as targets for psychiatric drugs, characteristics of psychopharmacological therapy in children and adolescents, ontogenetic influences on pharmacokinetics and pharmacodynamics, and pharmacotherapy in the outpatient setting. The part on classes of psychiatric medications, which covers antidepressants, antipsychotics, anxiolytics and sedative-hypnotics, mood stabilizers, and psychostimulants and other drugs used in the treatment of attention-deficit/hyperactivity disorder, provides sufficient background material to better understand how psychoactive drugs work, and why, when, and for whom they should be used. For each drug within a class, information on its mechanisms of action, clinical pharmacology, indications, dosages, and cognate issues are reviewed. In the third part, the disorder-specific and symptom-oriented medication is described and discerningly evaluated from a practical point of view, providing physicians with precise instructions on how to proceed. Psychiatric Drugs in Children and Adolescents includes numerous tables, figures and illustrations and offers a valuable reference work for child and adolescent psychiatrists and psychotherapists, pediatricians, general practitioners, psychologists, and nursing staff, as well as teachers.
  • 2009
    edited by Sidney Bloch, Stephen A. Green.
    Status: Not Checked OutLane Catalog Record
  • 2012 Ovid
    Daniel J. Carlat.
    I. General principles of effective interviewing -- II. The psychiatric history -- III. Interviewing for diagnosis, the psychiatric review of symptoms -- IV. Interviewing for treatment -- Appendixes -- References -- Index.
  • 1971
    [by] Roger A. MacKinnon [and] Robert Michels.
    Status: Not Checked OutLane Catalog Record
  • 2017
    Shawn Christopher Shea.
    Status: Not Checked OutLane Catalog Record
    Part I. Clinical interviewing: the principles behind the art -- 1. The delicate dance: engagement and empathy -- 2. Beyond empathy: cornerstone concepts and techniques for enhancing engagement -- 3. They dynamic structure of the interview: core tasks, strategies, and the continuum of open-endedness -- 4. Facilics: the art of transforming interviews into conversations -- 5. Validity techniques for exploring sensitive material and uncovering the truth -- 6. Understanding the person beneath the diagnosis: the search for uniqueness, wellness, and cultural context -- 7. Assessment perspectives and the human matrix: bridges to effective treatment planning in the initial interview -- 8. Nonverbal behavior: the interview as mime -- Part II. The interview and psychopathology: from differential diagnosis to understanding -- 9. Mood disorders: how to sensitivity arrive at a differential diagnosis -- 10. Interviewing techniques for understanding the person beneath the mood disorder -- 11. Psychotic disorders: how to sensitively arrive at a differential diagnosis -- 13. Personality disorders: before the interview begins- core concepts -- 14. Personality disorders: how to sensitively arrive at a differential diagnosis -- 15. Understanding and effectively engaging people with difficult personality disorders: the psychodynamic lens -- Part III. Mastering complex interviewing tasks demanded in everyday clinical practice -- 16. The mental status: how to perform and document it effectively -- 17. Exploring suicidal ideation: the delicate art of suicide assessment -- 18. Exploring violent and homicidal ideation: from domestic violence to mass murder.
  • 2007 Ovid
    [edited by] Alan B. Ettinger, Andres M. Kanner.
  • 2006
    American Nurses Credentialing Center.
    Status: Not Checked OutLane Catalog Record
  • 2016 Springer
    Joan A. Camprodon, Scott L. Rauch, Benjamin D. Greenberg, Darin D. Dougherty, editors.
    Major Depression -- Obsessive Compulsive Disorder -- Neuroimaging and the Neurocircuitry of OCD and Major Depression -- ECT -- VNS -- Ablative Neurosurgical Procedures for OCD and MDD -- DBS for OCED and MDD -- TMS & MST -- Animal Models -- Ethis & History -- Future of Neurosurgery.
  • 1994-
    Anita W. Finkelman.
    Status: Not Checked OutLane Catalog Record
  • 2007
    Katherine M. Fortinash, Patricia A. Holoday Worret.
    Status: Not Checked OutLane Catalog Record
    Nursing process -- Anxiety and related disorders -- Mood disorders -- Schizophrenia and other psychotic disorders -- Adjustment disorders -- Personality disorders -- Disorders of infancy, childhood, and adolescence -- Cognitive disorders : delirium, dementia, and amnestic disorders -- Substance-related disorders -- Eating disorders -- Sexual and gender identity disorders -- Appendixes: Suicide assessement and intervention guidelines ; Crisis and crisis intervention ; Client rights ; Guidelines for seclusion and restraint based on JCAHO standards ; Grief and loss : caregivers, clients, and families ; Spirituality as a dimension of the person ; Psychiatric and psychosocial therapies ; Psychopharmacology ; Comparison of developmental theories ; Defense mechanisms and strategies ; Standards of care for psychiatric - mental health nursing practice ; DSM-IV-TR classification.
  • 2016 Springer
    Luigi Mazzone, Benedetto Vitiello, editors.
    Introduction: Psychiatric comorbidities in autism: diagnostic and treatment challenges -- Mood Disorders in ASD -- Anxiety Disorders and ASD -- Obsessive-Compulsive Disorder and ASD -- Schizophrenia spectrum, other psychotic disorders and ASD -- Feeding and Eating disorders in ASD -- Disruptive Behavioural Disorders, Attention Deficit Hyperactivity Disorder in ASD -- Tourette's Disorder and tic disorder in ASD -- Substance-related disorders and ASD.
  • v. 1, 1961.
    Krapf, Eduard.
    Status: Not Checked OutLane Catalog Record
  • 2009
    Debra L. Klamen, Philip Pan.
    Status: Not Checked OutLane Catalog Record
  • 2012
    Debra L. Klamen, Philip Pan.
    Status: Not Checked OutLane Catalog Record
  • 2006
    Debra L. Klamen, Philip Pan.
    Status: Not Checked OutLane Catalog Record
  • 2015 Springer
    Pascual Ángel Gargiulo, Humberto Luis Mesones-Arroyo, editors.
    PART 1: EPISTEMOLOGICAL CONSIDERATIONS ABOUT THE STUDY OF NORMAL AND ABNORMAL HUMAN BEHAVIORS -- 1. Knowledge, by Philosophy or Science? Psychotherapy or Neuroscience?.- 2. Phenomenology as an approach method in the Neurosciences -- 3. Trends in Philosophy of Mind and in Philosophy of Neuroscience -- 4. Neurosciences, Neuroeconomics, and Metaphysics.- 5. Towards a Psychotherapy with a Philosophical Basis.- 6. DSM5: A Bioethical Overview.- PART 2: FROM BASIC NEUROSCIENCES TO HUMAN BRAIN.- 7. Brain Renin-Angiotensin System: A Novel Therapeutic Target for Psychostimulant and Alcohol Related Disorders?.- 8. Role of the Neuropeptide Angiotensin II in Stress and Related Disorders.- 9. Neurovascular Cognitive Alterations: Implication of Brain Renin-Angiotensin System (Ras). Therapeutic Opportunities and Risk Factors.- 10. Prevention of Stress-Induced Cognitive Impairment: Today and Tomorrow.- 11. Circadian Synchronization of Cognitive Functions.- 12. The Role of Iron and Other Trace Elements on Mental Development and Cognitive Function.- 13. New Insights in Glutamate-Mediated Mechanisms Underlying Benzodiazepines Dependence and Cocaine Vulnerability -- 14. Soy and Psychotropic Effects: A Brief Overview.- 15. Use of Psychotropic Drugs: Between the Medicalization and Rationality -- PART 3: NEUROSCIENCES, LEARNING, TEACHING AND THE ROLE OF SOCIAL ENVIRONMENT -- 16. Learning Styles: From Basic Investigation to Learning in the Classroom -- 17. Learning Styles and Strategies: The Importance of the Tool Selection.- 18. Attentional Capacity in Children: Intervention Programmes for its Development.- 19. Social Representation and Imagery of Labor -- Evaluation Process of the Psychosocial and Labor Vulnerability (PSLV) and its Relation With Mental Health.- PART 4: EXPLAINING HUMAN PATHOLOGICAL BEHAVIORS: FROM BRAIN DISORDERS TO PSYCHOPATHOLOGY.- 20. The Ying and Yang of Pain: Protective vs. Damaging.- 21. Neuropsychological Disorders after Mild Traumatic Brain Injury or Concussion.- 22. Animal Models of psychopathology and its relation to clinical practice.- 23. Biological Markers in Psychiatry and its Relation with Translational Approaches: Brief Historical Review.- 24. 'Two Hit' Neurodevelopmental Mechanisms In Schizophrenia: Focus On Animal Models And The Role Of BDNF -- 25. Translating the Glutamatergic Hypothesis of Schizophrenia through Homeostatic Regulation of Brain Glycine.- 26. Adenosine in the neurobiology of schizophrenia: potential adenosine receptor-based pharmacotherapy.- 27. Mindfulness and Neuroimaging.- 28. Clinical Magnetic Resonance Neuroimaging in Mild Cognitive Impairment and Alzheimeŕs Disease.
  • 2014
    sponsored by Department of Psychiatry Walter Reed National Military Medical Center, National Intrepid Center of Excellence Sleep Laboratory Department,, Center for the Study of Traumatic Stress, Department of Psychiatry, Uniformed Services University ; editior Mary Lee Dichtel, RN.
    List of speakers -- Welcome and an introduction to psychodynamics and pain intervention -- Introduction to psychodynamics and pain intervention -- Rehabilitation of the combat casualty and its implication for behavioral health specialists -- The use of spinal cord stimulator and pain clinic interventions for pain patients -- Transcranial magnetic stimuation (TMS) use for pain disorders -- Pain treatments and prescription opiod abuse: challenges and solutions -- Phantom limb pain: theories and therapies -- Psychoemotional issues and treatment of pain with acupuncture -- Speaker biographies.
  • 2014
    sponsored by Department of Psychiatry Walter Reed National Military Medical Center, Department of Medicine Walter Reed National Military Medical Center, National Intrepid Center of Excellence Sleep Laboratory Department,, Center for the Study of Traumatic Stress, Department of Psychiatry, Uniformed Services University ; editior Mary Lee Dichtel, RN.
    List of speakers -- The legacy of Kenneth L. Artiss -- Preface -- Introduction: sleep and DSM-V -- Overlap between sleep and psychiatric disoders: bidirectional relationships -- Healthy nights and better days: cognitive-behavioral treatments for insomnia -- Sleep issues in the military population -- Traumatic brain injury and sleep disorders -- Melatonin, light therapy and circadian rhythm disorders -- Speaker biographies.
  • 2008
    Cornelius Katona, Claudia Cooper, Mary Robertson.
    Status: Not Checked OutLane Catalog Record
  • 2006 Springer
    edited by Dilip V. Jeste, Joseph H. Friedman.
  • 2008
    David Goldberg, Linda Gask, Richard Morriss.
    Status: Not Checked OutLane Catalog Record
    Interview techniques and history-taking -- Examination of the mental state -- Risk assessments -- Syndromes and diagnosis -- Aetiology -- Investigations -- Treatment -- Prognosis -- Formulation -- Psychiatric aspects of physical disease -- Organic brain syndromes -- Schizophrenia and delusional disorders -- Bipolar disorders -- Internalizing disorders 1 : depression, anxiety and the fear disorders -- Internalizing disorders 2 : somatic presentations of emotional distress -- Externalizing disorders : misuse of alcohol and drugs, and eating disorders -- Personality disorders -- Disorders of early life : learning disability -- Childhood and adolescence -- Sexual and reproductive disorders -- Disorders of older people -- Services for people with mental health problems -- Ethical dilemmas and legal aspects.
  • 2008
    Jennifer Hoblyn, Judith Neugroschl, Asher B. Simon, Aaron B. Caughey.
    Status: Not Checked OutLane Catalog Record
  • 2010
    edited by Janis L. Cutler, Eric R. Marcus.
    Status: Not Checked OutLane Catalog Record
    Psychiatric assessment and treatment planning / Janis L. Cutler -- The psychiatric interview / Lyle Rosnick -- Mood disorders / Leo Sher, David A. Kahn, and Maria A. Oquendo -- Schizophrenia and other psychotic disorders / Thomas Smith, Ewald Horwath, and Francine Cournos -- Cognitive disorders and mental disorders due to general medical conditions / Jennifer M. Rucci and Robert E. Feinstein -- Anxiety disorders / Franklin R. Schneier ... [et al.] -- Alcohol and substance use disorders / Benjamin R. Bryan and Frances R. Levin -- Personality disorders / Eve Caligor, Frank Yeomans, and Ze'ev Levin -- Eating disorders / Michael J. Devlin and Joanna E. Steinglass -- Somatoform and factitious disorders / Kelli Jane K. Harding and Steven E. Hyler -- Suicide and violence / Cheryl A. Chessick and Robert E. Feinstein -- Psychological factors affecting medical conditions / Lucy A. Epstein and Eve Caligor -- Child, adolescent, and adult development / Jonathan A. Slater, Katharine A. Stratigos, and Janis L. Cutler -- Child and adolescent psychiatry / Daniel T. Chrzanowski ... [et al.] -- Psychotherapy / David D. Olds and Fredric N. Busch -- Pharmacotherapy and electroconvulsive therapy / Jonathan W. Stewart, L. Mark Russakoff, and Jessica Ann Stewart.
  • 2012 Karger
    volume editors, K.P. Ebmeier, J.T. O'Brien, J.-P. Taylor.
    Epidemiology of psychiatric symptoms in Parkinson's Disease -- Depression, apathy and anxiety disorders -- Apathy in Parkinson's Disease -- Disorders of visual perception in Parkinson's Disease and other Lewy body disorders -- Psychosis and Parkinson's Disease -- Sleep in Parkinson's Disease and dementia with Lewy bodies -- Sexual problems in Parkinson's Disease -- An update on impulse control disorders in Parkinson's Disease -- Neuropsychological features of early cognitive impairment in Parkinson's Disease -- Parkinson's Disease with dementia -- Somatoform disorders in Parkinson's Disease and dementia with Lewy bodies evidence underlying psychotic traits -- Drug-induced Parkinsonism and abnormal involuntary movements.
  • 2016
    Debra L. Klamen.
    Status: Not Checked OutLane Catalog Record
    Evaluation, assessment, and diagnosis -- Human behavior : theories of personality and development -- Human behavior : biologic and related sciences -- Disorders seen in childhood and adolescence -- Neurocognitive disorders and consultation-liaison psychiatry -- Schizophrenia and other psychotic disorders -- Psychotherapies -- Mood disorders -- Anxiety, obsessive-compulsive, trauma- or stressor-related, somatic symptom and dissociative disorders -- Personality disorders, human sexuality, and miscellaneous syndromes -- Substance-related disorders -- Psychopharmacology and other somatic therapies -- Law and ethics in psychiatry.
  • v. 1-4 , 1985- (including updates)
    chairman, editorial board, Robert Michels ; editor, Jesse O. Cavenar, Jr. ; editorial board members, H. Keith H. Brodie ... [et al.].
    Status: Not Checked OutLane Catalog Record
  • 2008
    editor, Joshua T. Thornhill IV.
    Status: Not Checked OutLane Catalog Record
    The clinical examination -- Personality disorders -- Psychotic disorders -- Mood disorders -- Anxiety disorders -- Cognitive and mental disorders due to general medical conditions -- Substance-related disorders -- Somatoform and associated disorders -- Sexual and gender issues -- Eating disorders -- Impulse disorders -- Child psychiatry -- Legal issues and forensic psychiatry.
  • 2012
    editor, Joshua T. Thornhill IV.
    Status: Not Checked OutLane Catalog Record
    "In this sixth edition of NMS Psychiatry, each chapter as well as the drug appendix has been updated to include the latest medications and treatment protocols. New chapters have been added on the emerging fields of emergency and geriatric psychiatry ..."--Provided by publisher.
  • 2008
    David A. Tomb.
    Status: Not Checked OutLane Catalog Record
  • 2006 Springer
    Mauro Mancia (ed.).
  • 2006
    by Charles Brenner.
    Status: Not Checked OutLane Catalog Record
  • 2014
    edited by Mali Mann.
    Status: Not Checked OutLane Catalog Record
    Introduction: Psychoanalytic impact of assisted reproductive technology / Mali Mann -- Psychoanalytic understanding of repeated in-vitro fertilization trials, failures, and repetition compulsion / Mali Mann -- Family complexes and oedipal circles: mothers, fathers, babies, donors, and surrogates / Diane Ehrensaft -- Psychoanalytic treatment of anxiety related to motherhood and the use of assisted reproductive technology / Terese Schulman -- Egg donors and sperm donors: parental identity formation / Mali Mann and Andrea Mann -- Infertility, trauma, and assisted reproductive technology: psychoanalytic perspectives / Manisha Near-Akhtar -- Assisted reproduction as explored in The Kids Are All Right / Katherine MacVicar.
  • 2009 Springer
    Tamara McClintock Greenberg.
    When the body intrudes: psychotherapy with older and medically ill adults -- Technology, idealization, and unconscious dynamics in the culture of medicine -- Trauma of medical illness -- Narcissistic aspects of aging and illness -- Transference and countertransference in aging and illness -- Self-destructive behaviors, masochistic dynamics, and illness -- Cognitive changes and implications for the therapeutic encounter -- What we know and what we don't: the influence of psychological factors on medical illness -- Hope and grief: the introduction of an emotional language.
  • 2011 Wiley
    by Deborah L. Cabaniss, Sabrina Cherry, Carolyn J. Douglas, Anna Schwartz.
    What is psychodynamic psychotherapy? -- Treatment for a mind in motion -- How does psychodynamic psychotherapy work? -- Evaluation -- Creating a safe place and beginning the evaluation -- Assessment of ego function -- Formulation: the problem, person, goals, resources model -- Indications for psychodynamic psychotherapy -- Beginning the treatment -- Informed consent and setting goals -- Setting the frame and establishing boundaries -- Developing a therapeutic alliance -- Therapeutic neutrality -- Conducting a psychotherapy session: decisions about length and frequency -- Our patients' feelings about us and our feelings about our patients -- Empathic listening -- Looking for meaning -- Medication and therapy -- Listen/reflect/intervene -- Learning to listen -- Learning to reflect -- Learning to intervene -- Conducting a psychodynamic psychotherapy: technique -- Affect -- Free association and resistance -- Transference -- Countertransference -- Unconscious conflict and defense -- Dreams -- Meeting therapeutic goals -- Improving self-perceptions and the ability to regulate self-esteem -- Improving relationships with others -- Improving characteristic ways of adapting -- Improving other ego functions -- Working through and ending -- Working through -- Termination -- Continuing to learn.
  • 2007 ebrary
    [edited by] Arthur E. Dell Orto and Paul W. Power.
    The disability paradigm / David Pfeiffer -- Understanding how disability is defined and conceptualized in the literature / Barbara J. Lutz and Barbara J. Bowers -- An integrative conceptual framework of disability : new directions for research / Denise G. Tate and Constance Pledger -- Transforming psychological practice and society : policies that reflect the new paradigm / Carol J. Gill, Donald G. Kewman, and Ruth W. Brannon -- Social work practice with people with disabilities in the era of disability rights / Richard L. Beaulaurier and Samuel H. Taylor -- Models of disability : implications for the counseling profession / Julie F. Smart and David W. Smart -- The contribution of the physically and mentally handicapped to development / Jean Vanier -- Personal perspective : coping with a journey toward recovery : from the inside out / Dale Walsh -- Psychological adaptation to chronic illness and disability : a primer for counselors / Hanoch Livneh and Richard F. Antonak -- Objective self-awareness and stigma : implications for persons with visible disabilities / Andrew A. Phemister and Nancy M. Crewe -- Psychosocial issues of women with physical disabilities : the continuing gender debate / Margaret A. Nosek and Rosemary B. Hughes -- Female sexuality and spinal cord injury : counselling implications / Eva Miller and Irmo Marini -- Cross-cultural counseling issues of males who sustain a disability / Irmo Marini -- Psychiatric and psychological issues in survivors of major disasters / Carol S. North -- Quality of life and psychosocial adaptation to chronic illness and acquired disability : a conceptual and theoretical synthesis / Malachy Bishop -- Six principles relating disability and psychological adjustment / Franklin C. Shontz -- Personal perspective : using rational emotive behavior therapy techniques to cope with disability / Albert Ellis -- Family decision making in foregoing life-extending treatments / Virginia P. Tilden ... [et al.] -- My child is not my carer : mothers with physical disablities and the well-being of children / Ora Prilleltenshy -- Parenting a child with a chronic medical condition / Jane Case-Smith -- In the midst of a hurricane : a case study of a couple living with AIDS / Lydia P. Buki, Lori Kogan, Bethanne Keen, and Patti Uman -- Parental illness, family functioning, and adolescent well-being : a family ecology framework to guide research / Sara Pedersen -- Life's challenges : curse or opportunity? Counseling families of persons with disabilities / Mary R. Hulnick and H. Ronald Hulnick -- Personal perspectives : my life with muscular dystrophy : lessons and opportunities / Robert P. Winske -- Dealing with Spina Bifida : mother's perspective / Janet Lingerman -- The construct of hope in the rehabilitation process / Amy B. Collins and Marvin D. Kuehn -- Spirituality in disability and illness / Judy Kaye and Senthil Kumar Raghavan -- Spiritual factors and adjustment in medical rehabilitation : understanding forgiveness as a means of coping / Jon R. Webb -- The psychosocial impact on survivors of extraordinary, stressful, and traumatic events : principles and practices in critical incident response for rehabilitation counselors / Mark A. Strebnicki -- War, death, and bereavement : how we can help / Joan Beder -- Users of assistive technology : the human component / Martin G. Brodwin, Tristen Star, and Elizabeth Cardoso -- Changes in attitudes toward people with handicaps / Beatrice A. Wright -- Personal perspective : recovery and the rehabilitation process : a personal journey / James T. Herbert -- The implications of positive psychology and wellness for rehabilitation counselor education / Irmo Marini and Mitka Chacon -- "Successful aging" : a disability perspective / Meredith Minkler and Pamela Fadem -- The promise of the International classification of functioning, disability, and health (ICF) -- Recovery from psychiatric disabilities / Patricia B. Nemec and Cheryl J. Gagne -- Psychological adaptation to disability : perspectives from chaos and complexity theory / Hanoch Livneh and Randall M. Parker -- Eugenics, euthanasia, and physician-assisted suicide : an overview for rehabilitation professionals / Steve Zanskas and Wendy Coduti -- Reflections and considerations / Arthur E. Dell Orto and Paul Power -- Aging and disability : toward a unified agenda / Irving Kenneth Zola -- Personal statement : life lessons taught me by my disability / Alfred H. DeGraff -- Personal statement : one more burden, a mother's perspective / Bernadette.
    Also available: Print – 2007
  • 2008 Springer
    Holly Hazlett-Stevens.
    "One of the hallmarks of generalized anxiety disorder, along with diffuse pathological worry and somatic complaints, is its resistance to therapy. Of available treatment modalities for GAD, cognitive-behavioral therapy garners the best empirical support in terms of successful long-term results. Psychological Approaches to Generalized Anxiety Disorder offers clinicians a wide variety of CBT strategies to help clients develop core anxiety-reduction skills, presented so that readers can hone their own clinical skills. Concise without skimping on information, this book reviews current theory and research, and addresses important diagnostic issues." "Psychological Approaches to Generalized Anxiety Disorder has much information of interest to new and seasoned clinicians, clinical researchers, and academic psychologists. It is also an especially valuable reference for graduate students treating or studying the anxiety spectrum."--BOOK JACKET.
  • 2013 Springer
    Brian I. Carr, Jennifer Steel, editors.
    Psychoneuroimmunology and cancer : incidence, progression, and quality of life -- Inflammation, chronic disease, and cancer : is psychological distress the common thread? -- Psychological aspects of hereditary cancer risk counseling and genetic testing -- Mastectomy to prevent breast cancer : psychosocial aspects of women's decision-making -- Decision aids in advanced cancer -- Cancer fatalism : attitudes toward screening and care -- Positive psychology perspectives across the cancer continuum : meaning, spirituality, and growth -- Stress, coping, and hope -- Religiousness and spirituality in coping with cancer -- Controversies in psycho-oncology -- Psychosocial interventions for couples coping with cancer : a systematic review -- The impact of cancer and its therapies on body image and sexuality -- Cancer caregivership -- Psychosocial interventions in cancer -- Quality of life -- Exercise for cancer patients : treatment of side effects and quality of life -- Use of the classic hallucinogen Psilocybin for treatment of existential distress associated with cancer -- The placebo and nocebo effects in cancer treatment -- Psychological factors and survivorship : a focus on post-treatment cancer survivors -- Complementary mind-body therapies in cancer -- End-of-life communication in cancer care -- The intersection between cancer and caregiver survivorship -- Resources for cancer patients -- Bringing it all together.
  • 2006 CRCnetBASE
    Thomas Strentz.
    Part I: Basic concepts -- American Psychiatric Association -- Characteristics of effective hostage/crisis negotiators -- Cross-trained versus cross-qualified -- Non-law enforcement negotiators -- One on one just isn't right -- Stress and the hostage/crisis negotiator -- Part II: Dealing with the other victim -- Negotiating with normal people -- Negotiating with the adolescent hostage taker -- Negotiating with the inadequate personality -- The antisocial personality disorder (it's all about me!) hostage-taker -- Negotiating with the paranoid schizophrenic hostage-taker -- The bipolar (I'm focused and flying high!) hostage-taker -- The suicidal hostage-holder -- Police-assisted suicide -- Crisis negotiations in the correctional setting -- Negotiating with the extremist -- Part III: Crisis resolution indicators -- Indicators of subject surrender -- Indicators of volatile negotiations -- Part IV: Group dynamics -- Group think -- Creative criteria for constructive deviation from crisis negotiation guidelines -- Part V: Hostage issues -- Phases of a hostage crisis -- The Stockholm syndrome -- What do you say to a hostage?
  • 2007 Springer
    Jayne Cockburn and Michael E. Pawson (eds.).
  • 2011 Springer
    Sherry Pagoto, editor.
    Psychological Co-morbidities of Obesity -- Psychological Issues in Adults with Type 2 Diabetes -- Psychological Co-morbidities of Cardiovascular Disease -- Psychological Co-morbidities of Cancer -- Tobacco Addiction and Psychological Co-morbidities -- Psychological Co-morbidities of HIV/AIDS -- Psychological Co-morbidities in Patients with Pain -- Psychiatric Disorders, Stress, and Their Treatment Among People with Multiple Sclerosis -- Psychological Co-morbidities of Dementia -- Psychological Co-morbidities of Irritable Bowel Syndrome -- Psychological Co-morbidities of COPD.
  • 2007 Karger
    volume editors, P. Porcelli, N. Sonino.
    Development of a new assessment strategy in psychosomatic medicine: the diagnostic criteria for psychosomatic research / S. Fabbri ... [et al.] -- Psychosocial approach to endocrine disease / N. Sonino, E. Tomba, G.A. Fava -- Psychological factors affecting functional gastrointestinal disorders / P. Porcelli, O. Todarello -- Psychological factors affecting oncology conditions / L. Grassi ... [et al.] -- Psychological factors affecting cardiologic conditions / C. Rafanelli ... [et al.] -- Toward a biopsychosocial approach to skin diseases / A. Picardi, P. Pasquini -- Psychological factors affecting medical conditions in consultation-liaison psychiatry / A. Bellomo ... [et al.] -- Psychological factors affecting medical conditions in consultation-liaison psychiatry / A. Bellomo ... [et al.] -- Psychological factors affecting eating disorders / S. Fassino ... [et al.].
  • 2011 WHO
    [writing and editorial team, Leslie Snider, Mark van Ommeren and Alison Schafer].
    Chapter 1. Understanding PFA -- Chapter 2. How to help responsibly -- Chapter 3. Providing PFA -- Chapter 4. Caring for yourself & your colleagues -- Chapter 5. Practise what you have learned.
    Also available: Print – 2011
  • 2007 Springer
    Tamara McClintock Greenberg.
  • 2010
    Vanessa Maria Vega.
    Media can seem more or less real. News shows pictures of actual events, feature films show pictures that are contrived, and all media offer content that can be taken as reality or fantasy depending on features of the media and beliefs viewers bring to the experience. Chapter 1 reviews features of the media and individual differences that interact to influence perceived realism of media. Chapter 2 describes two experiments that manipulate perceived realism in order to examine effects on emotion, cognitive effort and memory, employing psycho-physiological indices of arousal and cognitive effort. In both experiments, video clips were framed as "Real People" or "Actors, " reversing frames for half the participants while holding content constant. In Experiment 1, participants (N = 32) viewed 40 or 80 video clips and completed a recognition memory test 15 minutes after exposure. Video clips showing highly arousing content increased skin conductance levels when labeled "Real People" versus "Actors, " indicating increased motivation activation in response to stimuli with survival significance. Video clips labeled "Actors" decreased heart rate variability levels, indicating increased cognitive effort during processing. Participants showed increased recognition memory for audiovisual details in high arousal video clips labeled "Real People" versus "Actors." In Experiment 2, participants (N = 62) viewed the 80 video clips from Experiment 1. Video clips labeled "Real People" were rated as more involving, useful for survival, and typical than "Actors." High arousal content was rated as more involving, useful, and atypical than low-arousal content. 24 hours after exposure, participants showed better free recall and recognition memory for audiovisual details in high arousal clips labeled "Real People" versus "Actors." In sum, framing highly arousing video content as "Real people" increased physiological arousal and memory for audiovisual details. Chapter 3 discusses implications of perceived realism research for information consumers. Previous research has shown that people tend to believe what they perceive (Gilbert, 1991), and to respond to media as though it were real life (Reeves & Nass, 1996). Given the prevalent role of media in daily environments, and the lack of institutional oversight to assure the veracity of mediated information, information consumers are responsible for having the skills and motivation to evaluate sources and credibility in order to avoid Reality Monitoring failures in both individual and cultural memory (e.g. Johnson, 2007). Media features that elicit automatic sensory encoding processes are more likely to produce vivid memories (e.g. Lang, 2009), which are likely to be attributed to veridical sources (Johnson, 2006) and used in informing beliefs and actions (Shrum, 2009). Media literacy generally aims to shift information consumers from habits of automatic to critical processing. Cognitive approaches to media literacy interventions may include: a) increasing awareness of media features that elicit automatic sensory encoding (e.g. arousing content, edits, large screens), and b) reminding media users to consider the constructed nature and representational aspects of media portrayals. Focusing on elements of media construction offers a form of reappraisal which may interfere with automatic sensory encoding by increasing cognitive effort and reducing arousal responses to highly arousing content.
  • 2013
    editors, Gerald P. Koocher, John C. Norcross, Beverly A. Greene.
    Status: Not Checked OutLane Catalog Record
    Part I. Assessment and diagnosis -- 1. Lifetime prevalence of mental disorders in the general population / Christie P. Karpiak and Brian A. Zaboski -- 2. Conducting a mental status examination / Robert W. Baker and Paula T. Trzepacz -- 3. Improving diagnostic and clinical interviewing / Rhonda S. Karg, Arthur N. Wiens, and Ryan W. Blazei -- 4. Increasing the accuracy of clinical judgment (and thereby improving patient care) / David Faust -- 5. Assessing suicidal risk / Kenneth S. Pope and Melba J.T. Vasquez -- 6. Assessment of malingering on psychological measures / Richard Rogers and Nathan D. Gillard -- 7. Identifying and assessing alcohol, drug, and tobacco use disorders / Linda Carter Sobell, Mark B. Sobell, and Sean M. Robinson -- 8. Interviewing children's caregivers / Carolyn S. Schroeder and Eve-Lynn Nelson -- 9. Evaluating the medical components of childhood developmental and behavioral disorders / Nhung T. Tran and James L. Lukefahr -- 10. Using the DSM-5 and ICD-11 in forensic and clinical applications with children across racial and ethnic lines / Ronn Johnson -- 11. Assessing strengths in clinical practice / Tayyab Rashid -- 12. Evaluating dementia / Elise Caccappolo -- 13. Using the International Classification of Diseases system (ICD-10) / Michael C. Roberts and Spencer C. Evans -- 14. Taking a client's sexual history / Judith C. White -- 15. Screening for sexual offender risk / David Medoff and Sarah J. Sternlieb -- 16. Assessing personality disorders / Whitney L. Gore and Thomas A. Widiger. Part II. Psychological testing -- 17. Adult neuropsychological assessment / Aaron P. Nelson and Margaret O'Connor -- 18. Developmental neuropsychological assessment / Jane Holmes Bernstein, Betsy Kammerer, and Celiane Rey-Casserly -- 19. Assessment and intervention for executive dysfunction / Robert M. Roth, Peter K. Isquith, and Gerard A. Gioia -- 20. Assessing and managing concussion / Gerard A. Gioia -- 21. Assessing MMPI-2 profile validity / James N. Butcher -- 22. Interpreting clinical scale scores on the MMPI-2 / John R. Graham -- 23. Interpreting supplementary scales of the MMPI-2 / Roger L. Greene and Lacey M. Sommers -- 24. Understanding and using the MMPI-2-RF / Yossef S. Ben-Porath -- 25. Interpreting the family of Millon clinical inventories / Seth Grossman and Theodore Millon -- 26. Interpreting test scores and their percentile equivalents / Thomas P. Hogan -- 27. Locating information about psychological tests and measures / Thomas P. Hogan -- 28. Applying Rorschach assessment / Irving B. Weiner -- 29. Assessing the quality of a psychological testing report / Gerald P. Koocher and Celiane Rey-Casserly. Part III. Individual adult treatment -- 30. Compendium of psychotherapy treatment manuals / Michael J. Lambert -- 31. Compendium of empirically supported treatments / Dianne L. Chambers and E. David Klonsky -- 32. Compendium of treatment adaptations / John C. Norcross and Bruce E. Wampold -- 33. Compendium of evidence-based therapy relationships / John C. Norcross and Michael J. Lambert -- 34. Applying the stages of change / James O. Prochaska, John C. Norcross, and Carlo C. Diclemente -- 35. Enhancing patient adherence to treatment / M. Robin Dimatteo -- 36. Treating and managing care of the suicidal patient / Bruce Bongar and Glenn R. Sullivan -- 37. Intervening with clients in crisis / Kenneth France -- 38. Treating borderline personality disorder / Kenneth N. Levy -- 39. Treating reluctant and involuntary clients / Stanley L. Brodsky and Caroline Titcomb -- 40. Conducting motivational interviewing / Theresa B. Moyers and Daniel J. Fischer -- 41. Assessing and treating attention-deficit/hyperactivity disorder / Robert J. Resnick -- 42. Assessment and treatment of anger as a clinical problem / Raymond Digiuseppe -- 43. Diagnosis, assessment, and treatment of female sexual dysfunctions / Leonard R. Derogatis and Lori A. Brotto -- 44. Diagnosis, assessment, and treatment of male sexual dysfunctions / Leonard R. Derogatis and Lori A. Brotto -- 45. Working with patients at risk for HIV and other sexually transmitted diseases / Michael P. Carey and Peter A. Vanable -- 46. Treating women in psychotherapy / Laura S. Brown -- 47. Psychotherapy with lesbian, gay, and bisexual clients / Kristin A. Hancock -- 48. Practicing psychotherapy with older adults / Brian D. Carpenter and Bob G. Knight -- 49. Managing sexual feelings for patients in psychotherapy / Kenneth S. Pope -- 50. Improving completion of therapeutic homework / Michael A. Tompkins -- 51. Conducting evaluations of client outcomes and satisfactions / Michael J. Lambert and Kara Cattani -- 52. Repairing ruptures in the therapeutic alliance / Jeremy D. Safran and Catherine Boutwell -- 53. Reducing resistance in psychotherapy / Clifton W. Mitchell -- 54. Implementing stimulus control therapy for insomnia / Richard R. Bootzin -- 55. Terminating psychotherapy / Oren Shefet and Rebecca Coleman Curtis -- 56. Using hypnosis to invite relaxation / Douglas Flemons -- 57. Working with the religiously committed client / P. Scott Richards -- 58. Practicing psychotherapy with adults who have cognitive impairments / Kathleen B. Kortte -- 59. Selecting a treatment format / Larry B. Feldman -- 60. Treating the effects of psychological trauma / Laura S. Brown -- 61. Working with patients who have been sexually abused by previous therapists and clergy / Kenneth S. Pope -- 62. Counseling people living with HIV / Priscilla Dass-Brailsford -- 63. Treating bipolar spectrum disorders / Elizabeth Brondolo -- 64. Tailoring treatments to the patient's race and ethnicity / Guillermo Bernal and Melanie M. Domenech Rodríguez -- 65. Considerations in treating people with disabilities / Rochelle Balter -- 66. Practicing harm reduction / Andrew Tatarsky -- 67. Therapy with victims of hate crimes / Glenda M. Russell and Christopher G. Hawkey -- 68. Assessing and treating nonsuicidal self-injury / E. David Klonsky -- 69. Conducting psychotherapy with clients when English is not the first language / Rafael Javier and Lillian Comas-Díaz -- 70. Understanding sexuality in the context of disability / Linda R. Mona and Kimberly Smith -- 71. Helping patients cope with chronic medical illness / Carol D. Goodheart and Korey K. Hood -- 72 Locating the best research evidence for evidence-based practice / Lauren A. Maggio and Marilyn L. Tinsley -- 73. Preventing relapse / Katie Witkiewitz. Part IV. Couples, family, and group treatment -- 74. Recruiting, selecting, and preparing patients for interpersonal group psychotherapy / Victor J. Yalom -- 75. Conducting parent management training / Melanie M. Nelson and Sheila M. Eyberg -- 76. Conducting couple and family therapy / Jay L. Lebow -- 77. Treating high-conflict couples / Susan Heitler -- 78. Treating partner infidelity / Don-David Lusterman -- 79. Conducting psychoeducational groups / Gary M. Burlingame and Sean Woodland -- 80. Using genograms in assessment and therapy / Sueli S. Petry and Monica McGoldrick -- 81. Treating bullying behaviors among youth / Susan M. Swearer -- 82. Treating enuresis and encopresis / Patrick C. Friman -- 83. Treating veterans and military families / Marjan Ghahramanlou-Holloway and Jennifer L. Bakalar -- 84. Assessing and treating autism spectrum disorders / James A. Mulick and Courtney E. Rice. Part V. Child and adolescent treatment -- 85. Treating the behaviorally disordered child / Sheila M. Eyberg -- 86. Helping children cope with chronic mental illness / Lauren Mednick -- 87. Engaging the reluctant adolescent / Alice K. Rubenstein -- 88. Interviewing children about sexual abuse / Karen J. Saywitz and Joyce S. Dorado -- 89. Treating child sexual abuse / Kathryn Kuehnle and Mary Connell. Part VI. Biology and pharmacotherapy -- 90. Adult psychopharmacology / Christine Blasey, Joseph K. Belanoff, Charles Debattista, and Alan F. Schatzberg -- 91. Understanding side effects and warnings in psychopharmacology / Elain Orabona Foster and Ruth Roa-Navarrete -- 92. Pediatric psychopharmacology / Colleen A. Ryan and Michael L. Trieu -- 93. Common drugs of abuse and their effects / Christopher J. Correia and James G. Murphy -- 94. Herbal treatments for psychological disorders / Paula J. Biedenharn and Brian A. Kiernan -- 95. Medical conditions that may present as psychological disorders / William J. Reed -- 96. Normal medical laboratory values and measurement conversions / Gerald P. Koocher -- 97. Use of height and weight assessment tools / Nancie H. Herbold and Sari Edelstein -- 98. Dietary supplements and psychological functioning / Sari Edelstein and Nancie H. Herbold. Part VII. Self-help resources -- 99. Recommended self-help books, autobiographies, and films / John C. Norcross and Linda F. Campbell -- 100. Recommended homework during psychotherapy with couples and individuals / Arthur E. Jongsma, Jr. -- 101. Recommended self-help Internet resources for patients / John M. Grohol -- 102. Recommended online computer-assisted treatments / Luciano L'Abate. Part VIII. Ethical and legal issues -- 103. Ethical principles of psychologists and code of conduct -- 104. Dealing with licensing boards and ethics complaints / Gerald P. Koocher and Patricia Keith-Spiegel -- 105. Defending against legal (malpractice and licensing) complaints / Robert Henley Woody -- 106. Minimizing your legal liability risk following adverse events of patient threats / Jeffrey N. Younggren -- 107. Dealing with subpoenas / Linday Childress-Beatty and Gerald P. Koocher -- 108. Confronting an unethical colleague / Patricia Keith-Spiegel -- 109. Recognizing, assisting, and reporting the impaired psychologist / Gary R. Schoener -- 110. Understanding special education law / Linda Wilmshurst. Part IX. Forensic practice -- 111. Understanding involuntary psychiatric hospitalization / Stuart A. Anfang and Paul S. Appelbaum -- 112. Applying standards for use of physical restraint and seclusion / Thomas Graf -- 113. Understanding legal terms of special interest in mental health practice / Gerald P. Koocher -- 114. Applying the duty to protect and warn / James L. Werth, Jr. and Jennifer Stroup -- 115. Preparing and giving expert testimony / Stanley L. Brodsky and Tess M.S. Neal -- 116. Evaluating competence to stand trial / Carla A. Lourenco -- 117. Conducting a child custody evaluation / Robin M. Deutsch -- 118. Assessing and responding to aggressive and threatening clients / Leon Vandecreek. Part X. Financial and insurance matters -- 119. Handling money matters and gifts in psychological practice / Jeffrey E. Barnett and Allison J. Shale -- 120. Understanding professional liability insurance / Bruce E. Bennett -- 121. Managing your managed care contracts / Gerald P. Koocher -- 122. Setting fees for psychological services / Kavita J. Shah and John C. Norcross -- 123. Navigating adverse managed care decisions / Katherine C. Nordal and Shirley Ann Higuchi. Part XI. Practice management -- 124. Making good referrals / Steven Walfish and Jeffrey Zimmerman -- 125. Prototype mental health records / Gerald P. Koocher -- 126. Fulfilling informed consent responsibilities / Kenneth S. Pope -- 127. Elements of authorization forms to release or request client's records / Edward Zuckerman -- 128. Understanding fundamentals of the HIPAA privacy rule / Alan C. Nessman -- 129. Common clinical abbreviations and symbols / John C. Norcross and Brian A. Zaboski -- 130. Creating a professional living will for psychologists / Stephen A. Ragusea -- 131. Understanding statistics in the research literature / William F. Chaplin and Niketa Kumar -- 132. Selecting and relying on an attorney / Robert Henley Woody -- 133. Managing real-time telepsychology practice / Eve-Lynn Nelson and Teresa A. Lillis -- 134. Optimizing the use of technology in psychology with best practice principles / Marlene M. Maheu, Joseph McMenamin, and Myron L. Pulier -- 135. Practicing in the era of social media / Jeffrey E. Barnett and Keely Kolmes -- 136. Finding, evaluating, and using smartphone applications / Marlene M. Maheu, Myron L. Pulier, and Sylvain Roy. Part XII. Prevention, consultation, and supervision -- 137. Helping people cope with disasters / Eric M. Vernberg and Erin P. Hambrick -- 138. Establishing a consultation agreement / Len Sperry -- 139. Interacting with the media / Lilli Friedland and Florence Kaslow -- 140. Conducting effective clinical supervision / Nicholas Ladany -- 141. Responsibilities and liabilities in supervision / Carol A. Falender and Edward P. Shafranskie -- 142. Cultivating relationships and coordinating care with other health professionals / John C. Linton -- 143. Consulting on end-of-life decisions / James L. Werth, Jr. and Erica Whiting -- 144. Psychotherapist self-care checklist / John C. Norcross and James D. Guy, Jr. -- 145. Conducting evidence-based prevention / Sha'kema M. Blackmon and Elizabeth M. Vera.
  • 2012 Springer
    Katharine D. Barnard, Cathy E. Lloyd, editors.
    Psychological issues are increasingly recognised to be of high importance in diabetes management. Understanding the psychosocial barriers facing individuals and their families and being able to provide the tools to support them to overcome those barriers is an essential part of diabetes care.Psychology and Diabetes Care: A Practical Guide is a concise handbook for the practicing diabetes clinician who is interested in gaining a better understanding of their patients, and in learning effective skills to better support patients. The book explores common psychological problems associated with diabetes, gives insight into how diabetes is experienced in children, adolescents and special groups, and provides practical advice on providing psychological support to individuals with this serious long-term condition.
  • 2015 ClinicalKey
    edited by Benjamin A. Bensadon.
    1. Goal-Oriented care -- 2. Family caregiving -- 3. Attitudes, beliefs, and behavior -- 4. Communication -- 5. Culture of medicine -- 6. Psychology consult: when and why -- 7. Managing safety and mobility needs of older drivers -- 8. Person-centered suicide prevention -- 9. End-of-life care -- 10. Experiential learning and "selling" geriatrics -- 11. Simulation education.
  • 2010 Springer
    Stuart C. Carr, editor.
    Introduction : The psychology of global mobility / Stuart C. Carr -- Human mobility in a global era / Adrian Furnham -- Mixed-methods approaches to contextually grounded research in settings of armed conflict and natural disaster / Kenneth E. Miller -- Ethical psychological practice with geographically mobile individuals and groups / Graham R. Davidson -- Mobility and personality / Irene Hanson Frieze and Man Yu Li -- Identity and global mobility / Phyllis Tharenou -- Global mobility, local economy : it's work psychology, stupid! / Stuart C. Carr -- The psychology of enforced mobility / Wendy Ager and Alastair Ager -- Global mobility and cross-cultural training / Jan Selmer -- Mobility and acculturation / John W. Berry -- Mobility and inclusion / Douglas C. Maynard, Bernardo M. Ferdman, and Tabitha R. Holmes -- New settlement with wellbeing in oppressive contexts : a liberation psychology approach / Sonia Hernández-Plaza ... [et al.] -- Mobility and careers / Kerr Inkson and Kaye Thorn -- Global mobility and bias in the workplace / Astrid Podsiadlowski and Colleen Ward -- Technology, mobility, and poverty reduction / Lori Foster Thompson and Stephen G. Atkins.
  • 2006 ScienceDirect
    Purcell, Catherine E.; Arrigo, Bruce A.
    1. Introduction -- 2. Paraphilia and lust murder -- 3. Sexual homicide and serial murder : what do we know? -- 4. An integrative model : what do we need? -- 5. The case of Jeffrey Dahmer -- 6. Dahmer, paraphilia, and lust murder : testing the models -- 7. In search of meaning : on theory construction and model building -- 8. Implications and conclusions.
  • 2005 ScienceDirect
    George Comstock, Erica Scharrer.
  • 2012 Springer
    Jacob A. Belzen, editor.
    "In recent years, psychology of religion has experienced a remarkable comeback: research is expanding rapidly, benefiting from a genial scientific infrastructure. An important issue in psychology over a century ago, only a few decades later it vanished almost completely. Its unexpected international reemergence since the seventies has been facilitated by the work of visionaries with the energy and stamina to revive an entire branch of psychology. In 'Psychology of Religion: Autobiographical Accounts,' a number of these pioneers account for their development in this area, depicting the diverse contexts of their work, the difficulties they had to deal with, and the increasing contemporary possibilities for their field. Critical about their discipline and sometimes about themselves, they offer a unique assessment of the subject and show the way to further research and development. Thought-provoking topics discussed along the way include: The challenge of approaching religion from a psychological perspective; Psychology of religion as a natural extension of mainstream psychology; Why psychology of religion will continue to gain salience over time. 'Psychology of Religion: Autobiographical Accounts' will appeal to readers in general psychology, religious studies, and philosophy of science. Editor Jacob A. Belzen graduated in social sciences (Utrecht, Netherlands), history (Amsterdam, Netherlands), philosophy (Leuven, Belgium) and sciences of religion (Turku, Finland). He is a full professor at the University of Amsterdam, specializing in cultural psychology of religion, while also actively involved in empirical research on the history of his field. Recipient of various international awards, he counts among Europe's best-known psychologists of religion."--Publisher's website.
  • 2011 Springer
    Christopher Blazina, Güler Boyraz, David Shen-Miller, editors.
    There have been dramatic increases in the financial, emotional, and psychological investment in pets over the past four decades. The increasing importance of animal companions in people's lives has resulted in growing emphasis on the human-animal bond within academic literature. This book introduces practicing and emerging professionals to vital subject matter concerning this growing specialty area by providing an essential framework and information through which to consider the unique contextual backdrop of the human-animal bond.
  • 2015 Springer
    Dominic Upton, Penney Upton.
    This book addresses the psychological consequences of wounds and the psychological components of wound care, building on contemporary research evidence and presenting practical clinical guidelines. Particular emphasis is given to the psychological impact of both wounds and wound treatment. Implications for practice are discussed, making this book both educational and practical. Psychology of Wounds and Wound Care in Clinical Practice is aimed at clinicians, including GPs, vascular surgeons and physicians, nurses, especially tissue viability nurses, and podiatrists, and is also of interest to academic teachers and researchers.
  • 2009 Springer
    James M. Nelson.
    1. Introdcution to psychology, religion and spirituality -- 2. Science, religion and psychology -- 3. Religious traditions -- 4. Phenomenological approaches to religion and spirituality -- 5. Psychodynamic and relational approaches -- 6. Contemporary approaches and debates -- 7. Fundamentals of human development, religion, and spirituality -- 8. Religion and development in childhood and adolescence -- 9. Religion, spirituality , and development in adulthood -- 10. Religion, spirituality , and physical health -- 11. Religion, spirituality, and mental health -- 12. Practices and religious communities -- 13. Individual religious and spiritual practices -- 14. Helping relationships: counseling and spiritual growth -- 15. Looking Back -- Glossary -- Bibliography -- Author Index -- Subject Index.
  • 2011 Springer
    Graham Richards.
    The nature of the problem -- Mythos and logos -- Psychology's religious roots. Education and the child ; The American dimension ; Some early British religious psychologists ; A Catholic detour ; Religious origins of the concept of "psychology" ; Conclusions -- Psychology of religion. William James' the varieties of religious experience ; Classic psychology of religion ; The demise of classical psychology of religion ; Conclusion -- A boundary problem. John Macmurray ; Reinhold Niebuhr ; Paul Tillich ; Martin Buber ; The Union Theological Seminary connection ; Conclusion -- The authenticity of religious experience -- Religion and psychotherapy. Boston Emmanuel Movement (1906-1929) ; Britain between 1918 and c. 1980 ; The growth movement -- The problem of prayer -- Religion and personality -- The theism question -- Psychology and non-Christian religions -- Religion and psychological theory. Piaget : salvaging Protestantism by other means? ; Freud : the mysterious nature of psychoanalysis ; Gordon W. Allport (1897-1967) : the psychology of an Episcopalian ; Atheism and anti-religious psychology ; Conclusion -- Conclusions, hypotheses, suggestions and a stab at a personal "position statement". Religious doctrines beyond psychology's brief ; Religion and psychology essentially concerned with the same issues ; Religion is an inferior alternative to psychology ; Reconstructing the relationship ; Two issues for historians of psychology ; An attempt at a final position ; Concluding remarks.
  • 2012 Springer Protocols
    edited by Qing Yan.
    pt. I. Stress and immunity: biopsychosocial models. The role of psychoneuroimmunology in personalized and systems medicine / Qing Yan -- Psychoneuroimmunology: the experiential dimension / Elling Ulvestad -- Psychosocial job stress and immunity: a systematic review / Akinori Nakata -- Immune cells listen to what stress is saying: neuroendocrine receptors orchestrate immune function / Harlan P. Jone -- Physical activity, stress reduction, and mood: insight into immunological mechanisms / Mark Hamer, Romano Endrighi, and Lydia Poole -- pt. II. Translation of psychoneuroimmunology into personalized medicine: potential biomarkers and clinical implications. Translational implications of inflammatory biomarkers and cytokine networks in psychoneuroimmunology / Qing Yan -- Cytokines as potential biomarkers for Parkinson's disease: a multiplex approach / Darcy Litteljohn and Shawn Hayley -- Exploring the diagnostic potential of immune biomarker coexpression in Gulf War illness / Gordon Broderick, Mary Ann Fletcher, Michael Gallagher, Zachary Barnes, Suzanne D. Vernon, and Nancy G. Klimas -- Neuroimmune mechanisms of depression in heart failure / Jessica A. Jiménez and Paul J. Mills -- A reinterpretation of the Pathogenesis and Cure of Cancer According to the Psychoneuroimmunological Discoveries / Paolo Lissoni -- Aging microglia: relevance to cognition and neural plasticity / Rachel A. Kohman -- Autism spectrum disorders: from immunity to behavior / Milo Careaga and Paul Ashwood -- pt. III. Technologies and models in psychoneuroimmunology studies. Mouse testing methods in psychoneuroimmunology: an overview of how to measure sickness, depressive/anxietal, cognitive, and physical activity behaviors / Jason M. York, Neil A. Blevins, Tracy Baynard, and Gregory G. Freund -- The MRL model: an invaluable tool in studies of autoimmunity-brain interactions / Boris Sakić -- Interleukin-2 and the brain: dissecting central versus peripheral contributions using unique mouse models / John M. Petitto, Danielle Meola, and Zhi Huang -- Psychoneuroimmunology and natural killer cells: the chromium release whole blood assay / Mary Ann Fletcher, Zachary Barnes, Gordon Broderick, and Nancy G. Klimas -- The application of PET imaging in psychoneuroimmunology research / Jonas Hannestad -- The vaccination model in psychoneuroimmunology research: a review / Anna C. Phillips -- Using vaccinations to assess in vivo immune function in psychoneuroimmunology / Victoria E. Burns -- Translational bioinformatics in psychoneuroimmunology: methods and applications / Qing Yan.
  • v. 1-2, 2007.
    edited by Robert Ader.
    Status: Not Checked OutLane Catalog Record
  • 2014 Springer
    Ute Goerling, editor.
    Psycho-oncology is a thriving discipline in cancer care, and numerous research activities have been undertaken in the endeavor to improve treatment outcomes and to gain a better understanding of the psychological consequences of cancer. This book presents and discusses the latest findings from science and practice for a broad range of psychological and social issues related to cancer and its treatments. Not only are general psychosocial impacts of cancer described, but the very common fear of progression is elucidated. The relevance of psychooncology at different stages of disease (during oncological treatment, in rehabilitation, and during palliative care) is explained, and various psychooncological interventions are illustrated. Other important topics are the experience of being a cancer survivor, who may be cured but not be healthy, the psychological burden on relatives, and gender differences in coping with cancer. Quality of life and patient-reported outcomes are also commented on since they are among the key benchmarks for successful coping with the diagnosis of cancer, its treatment, and its late effects.
  • 2010
    edited by Jimmie C. Holland, William Breitbart, Paul B. Jacobsen ... [et al.]
    Status: Not Checked OutLane Catalog Record
  • 2005 ScienceDirect
    edited by Jennifer L. Hudson and Ronald M. Rapee.
    Genetics and the family environment / Thalia C. Eley and Jennifer Y.F. Lau -- The role of parenting in the development of psychopathology : an overview of research using the Parental Bonding Instrument / Gemma L. Gladstone and Gordon B. Parker -- Attachment and psychopathology : a lifespan perspective / Judy Ungerer and Catherine McMahon -- Interparental conflict, violence, and psychopathology / Jennifer L. Hudson -- Oppositional and conduct problems / David J. Hawes and Mark R. Dadds -- Attention-deficit/Hyperactivity Disorder (ADHD) and the family : a developmental psychopathology perspective / Eric J. Mash and Charlotte Johnston -- Family factors and the development of anxiety disorders / Natalie S. Gar, Jennifer L. Hudson and Ronald M. Rapee -- Eating disorders / Tracey Wolfe -- Familial risk factors for substance use disorders / Shelli Avenevoli, Kevin P. Conway, and Kathleen Ries Merikangas -- Parenting and personality disorders / Joel Paris -- Family factors in schizophrenia and bipolar disorder / Jill M. Hooley, Kristen A. Woodberry, and Caitlin Ferriter -- Depression and the family / Judy Garber -- Family involvement in psychotherapy : what's the evidence? / Katharina Manassis -- Clinical perspectives on involving the family in treatment / Frank M. Dattilio -- Family intervention and prevention of behavioural and emotional disorders in childhood and adolescence / Matthew R. Sanders and Alan Ralph.
  • 2015 Springer
    edited by Margarita Sáenz-Herrero.
    Gender has a fundamental influence on the human brain, not only by virtue of biological and hormonal differences between the sexes but also because of the impact of gender-specific cultural, social, anthropological, and environmental factors. Nevertheless, the relation of gender and psychopathology remains a largely neglected field. Gender perspective has been treated as a paradigm in this book on psychopathology because it determines the way in which a psychiatric symptom is defined, perceived, and understood. This conception of gender as being of key importance in the definition of psychiatric symptomatology is exceptional in the literature. The book opens by examining historical and cultural aspects of mental health in women worldwide and the relation of sex, brain, and gender, with coverage of both neurobiological and psychosocial aspects. The significance of gender with regard to specific aspects of psychopathology is then addressed in detail. A wide range of psychological disorders are considered, as well as hormonal influences and issues concerning body image, self identity, sexuality, and life instinct. It is hoped that this book will make a significant contribution in ensuring that gender perspective receives due attention within descriptive psychopathology.
  • 2006 Springer
    edited by Philip Gorwood, Michel Hamon.
  • 2014 Springer
    Megan Galbally, Martien Snellen, Andrew Lewis, editors.
    This book examines the role of psychopharmacological treatment in a range of disorders that may be encountered during pregnancy, including major depressive disorders, anxiety disorders, bipolar affective disorder, schizophrenia, eating disorders, and substance abuse. The natural history of each condition pre- and post-partum is analyzed, and the evidence for the efficacy of drug treatments, evaluated. Special attention is paid to the potential dangers of different treatment options for both mother and fetus, covering risks of malformation, pregnancy and obstetric risks, neonatal risks, and possible long-term consequences. The risks of not treating a particular condition are also analyzed. On the basis of the available evidence, management guidelines are provided that additionally take into account non-pharmacological options. Closing chapters consider the value of complementary and alternative medicine and ECT and explore future research directions.
  • 2014 Springer
    Luigi Grassi, Michelle Riba, editors.
    This practical manual presents the main drugs and protocols currently used in the psychopharmacological treatment of psychiatric disorders in cancer and palliative care settings and explores the principal issues involved in such treatment. Significant clinical challenges encountered in the psychopharmacological management of various psychiatric conditions are discussed, covering aspects such as side-effects and drug-drug interactions. Attention is also paid to the emerging theme of adjuvant use of psychotropic drugs for the treatment of symptoms or syndromes not primarily related to psychiatric disorders (e.g. pain, hot flashes). In addition, practical suggestions are provided for dealing with special populations, including children, the elderly, and people affected by severe mental illness. The book is designed to be easy to read and to reference: information is clearly displayed in concise tables and boxes, accompanied by further detail within the text and clinical vignettes. The authors include some of the most renowned clinicians working in the field of psycho-oncology.
  • 1978 Karger
    volume editor L. Valzelli.
    Also available: Print – 1978-
  • 2008 Springer
    Pamela Gallagher, Deirdre Desmond, Malcolm MacLachlan, editors.
  • 2009 Springer
    Regina Lederman, Karen Weis.
  • 2016 Springer
    Perry M. Nicassio, editor.
    1. The importance of the biopsychosocial model for understanding the adjustment to arthritis -- 2. Mechanisms of arthritis pain -- 3. Understanding and enhancing pain coping in patients with arthritis pain -- 4. Psychological factors in arthritis: cause or consequence? -- 5. Stress in arthritis -- 6. Socioeconomic disparities in arthritis -- 7. The heart of clinical relationships: doctor-patient communication in rheumatology -- 8. Resilience to chronic arthritis pain is not about stopping pain that will not stop: development of a dynamic model of effecttive pain adaptation -- 9. Sleep disturbance in rheumatic disease -- 10. Disability, limitations, and function for people for arthritis -- 11. Revisiting unequal treatment: disparities in access to and quality of care for arthritis -- 12. Evaluation of psychological distress in the rheumatology clinic -- 13. Physical activity and psychosocial aspects of arthritis -- 14. Evidence-based complementary and alternative medical approaches for arthritis -- 15. Enhancing clinical practice with community-based self-management support programs -- 16. The nature, efficacy, and future of behavioral treatments for arthritis -- Index.
  • 2008 Springer
    Ranjan Roy.
    "Although much of medical practice is research driven, the same cannot be said about the psychosocial interventions for chronic pain and illness. Psychological therapy for pain is dominated by cognitive-behavior therapy, which is demonstrably effective in a significant proportion of chronic pain sufferers. There is a clear need to broaden the base of psychosocial therapies for treating this hugely suffering population. Psychosocial Interventions for Chronic Pain goes a long way to correct the situation by examining the empirical bases of patient problems as well as offering evidence-supported approaches to their management. Ranjan Roy's introductory chapters explain how effectiveness is measured in psychosocial practice, and these concepts are clearly applied in compelling case examples." "Psychosocial Interventions for Chronic Pain brings a useful framework of ideas to all health and mental health professionals working with chronic pain patients, including psychologists, social workers, physicians, and nurses. The book's evidence-based orientation also makes it a valid text for specialized graduate courses on pain management."--Jacket.
  • 2012 Karger
    volume editors, G.A. Fava, N. Sonino, T.N. Wise.
    Principles of psychosomatic assessment / Fava, G.A., Sonino, N., Wise, T.N. -- The psychosomatic interview / Wise, T.N., Dellemonache, P.M.; Bachawati, M.M. -- Evaluating childhood adversity / Thabrew, H., de Sylva, S., Romans, S.E. -- Evaluating life events and chronic stressors in relation to health : stressors and health in clinical work / Theorell, T. -- Assessment of lifestyle in relation to health / Tomba, E. -- Assessment of sexual function in the medically ill : psychosomatic approach to sexual functioning / Balon, R. -- Psychological factors in medical disorders assessed with the diagnostic criteria for psychosomatic research / Porcelli, P., Todarello, O. -- Mood and anxiety in the medically ill / Bech, P. -- Assessment of personality in psychosomatic medicine : current concepts -- Cosci, F. -- Illness behavior / Sirri, L., Grandi, S. -- Assessment of psychological well-being in psychosomatic medicine -- Rafanelli, C., Ruini, C. -- Family assessment in the medical setting / Keitner, G.I. -- Relational ethics and psychosomatic assessment / Barbosa, A.
  • 2006 Ovid
    [edited by] Michael Blumenfield, James J. Strain.
  • 2014 Springer
    edited by Kurt Fritzsche, Susan H. McDaniel, Michael Wirsching.
    Psychosocial problems appear within a medical context worldwide, and are a major burden to health. Psychosomatic Medicine: An International Primer for the Primary Care Setting takes a uniquely global approach in laying the foundations of biopsychosocial basic care (such as recognizing psychosocial and psychosomatic problems, basic counseling, and collaboration with mental health specialists) and provides relevant information about the most common mental and psychosomatic problems and disorders. The scope of the book is interculturalit addresses global cultures, subcultures living in a single country, and strengthening the care given by physicians working abroad. This clinically useful book outlines best practices for diagnosing the most common biopsychosocialproblems and mastering the most common communication challenges (e.g. doctor-patient conversation, breaking bad news, dealing with difficult patients, family and health systems communication and collaboration). Every chapter integrates basic theoretical background and practical skills and includes trans-culturally sensitive material, important for work with patients from different cultures. Psychosomatic Medicine: An International Primer for the Primary Care Setting serves as an excellent resource for clinicians hoping to gain and develop knowledge and skills in psychosomatic medicine.
  • 2014 Springer
    Marc Lévêque ; preface by Bart Nuttin ; afterword by Marwan Hariz.
    Psychosurgery, or the surgical treatment of mental disorders, has enjoyed a spectacular revival over the past ten years as new brain stimulation techniques have become available. Neuromodulation offers new possibilities for the treatment of psychiatric disorders such as depression, obsessive-compulsive disorder (OCD), addiction, eating disorders and autism. This work presents the history of this unique specialty and investigates current techniques and ethical challenges. With a wealth of illustrations and detailed anatomical diagrams, it provides essential information for medical practitioners, as well as anyone else interested in the fascinating advances being made in neuroscience today.
  • 2008 Springer
    edited by Heinrich Bartuska ... [et al.].
  • 2013 Springer
    R. van Deth.
    Variations on a Theme: What is 'Real' Psychotherapy? -- Unconscious Scenarios: Psychodynamic Therapy -- In contact with yourself: client-centered therapy -- Learning by Doing: Behavior Therapy -- Thinking Differently: Cognitive Therapy -- Joy and Sorrow Together: Systems Therapy -- Tailored Therapy: What do we Measure and What do we Know? -- Pitfalls and Safety Nets: In Good Hands?.
  • 2016 Springer
    Sita Patel, Daryn Reicherter, editors.
    Immigrant youth life stressors -- Cognitive-behavioral therapy for immigrant youth: the essentials -- Family factors: immigrant families and intergenerational considerations -- School-based interventions -- Trauma and acculturative stress -- Combined psychotherapy with psychopharmacology -- Information systems and technology -- Treating forcibly displaced young people: global challenges in mental healthcare -- Immigrant youth and navigating unique systems that interact with treatment -- Cultural perspectives in the context of Western psychological mind-sets: the need for cultural sensitivity in the mental health of immigrant youth -- Index.
  • 2016 Springer
    Adriana Roncella, Christian Pristipino, editors.
    1. Complex psychoneural processes in ischemic heart disease: evidences for a systems medicine framework -- 2. Psychosocial risk factors and coronary artery disease -- 3. Psychological stress, inflammation, immunity, and coagulation intertwining in ischemic heart disease -- 4. The second brain and possible interactions with the heart -- 5. Sleep and dreams in cardiovascular pathophysiology -- 6. The role of gender in the mind-heart relationship -- 7. Integrated approach for cardiac patients and psychological interventions -- 8. Psycho-educational interventions and cardiac rehabilitation -- 9. Psychiatric pharmacotherapy in coronary artery disease patients -- 10. Evidence-based psychotherapy in ischemic heart disease: umbrella review and updated meta-analysis -- 11. Cognitive and behavioral psychotherapy in coronary artery disease -- 12. Mind-body practices for prevention and treatment of cardiovascular disease -- 13. Short-term psychotherapy in patients with acute myocardial infarction -- 14. Psychometric tests: epistemology, rationale, aims, and applicability in cardiology, open issues -- 15. Projective tests: the six-drawings test in ischemic heart disease -- 16. Verbal communication and effective communication: communication in the psychotherapeutic setting -- 17. Nonverbal communication: the forgotten frame -- 18. Psychotherapy for cardiac patients: selection of clinical cases, part I -- 19. Psychotherapy for cardiac patients: selection of clinical cases, part II -- 20. A model integrating psychotherapy into medical practices at San Filippo Neri Hospital in Rome, Italy -- 21. Model to integrate psychology/psychotherapy with medical activities at the Hospital of Terni, Italy -- 22. An integrative model of psychotherapy in medical practice according to GICR-IACPR.
  • 2015 Springer
    Omar C.G. Gelo, Alfred Pritz, Bernd Rieken, editors.
    This book provides readers with essential information on the foundations of psychotherapy research, and on its applications to the study of both psychotherapy process and outcome. The aim is to stimulate a reflection on these issues in a way that will benefit researchers and clinicians, as well as undergraduate and graduate students, at different levels and from different perspectives. Accordingly, the book presents a balanced mix of chapters summarizing the state of the art in the field from different viewpoints and covering innovative topics and perspectives, reflecting some of the most established traditions and, at the same time, emerging approaches in the field in several countries. The contributors, who were invited from among the experts in our national and international professional networks, also represent a healthy mix of leading figures and young researchers. The first part of the book addresses a number of fundamental issues in psychotherapy research at a historical, philosophical, and theoretical level. The second part of the book is concerned with research on psychotherapy processes; in this regard, both quantitative and qualitative approaches are given equal consideration in order to reflect the growing relevance of the latter. The book's third and last part examines research on psychotherapy outcomes, primarily focusing on quantitative approaches. Offering a balanced mix of perspectives, approaches and topics, the book represents a valuable tool for anyone interested in psychotherapy research.
  • 1980-
    contributors, M. Ackenheil ... [et al.] ; editors, F. Hoffmeister, G. Stille.
    Part 1, Antipsychotics and antidepressants ; Part 2, Anxiolytics, gerontopsychopharmacological agents ; Part 3, Alcohol and psychotomimetics, psychotropic effects of central acting drugs ;
  • 2008
    Jerrold S. Maxmen, Sidney H. Kennedy, Roger S. McIntyre.
    Status: Not Checked OutLane Catalog Record
    Antipsychotics -- Agents for treating movement disorders -- Antidepressants -- Dementia-treating agents -- Mood stabilizers -- Antianxiety agents -- Hypnotics -- Stimulants and stimulant-like agents.
  • 2008 Springer
    Rosa Margesin ... [et. al.], editors.
  • Google Books
    udgivet paa foranledning af Direktoratet for fængselsvæsenet ved George E. Schrøder ...
    Also available: Print – v. 1, 1917.
  • 2006 Springer
    N. Kato, M. Kawata, R.K. Pitman, (eds.).
  • 2016 Springer
    editors, Philip Kumanov, Ashok Agarwal.
  • 2016 Karger
    volume editors, Jean-Pierre Bourguignon, Anne-Simone Parent.
    The emerging role of epigenetics in the regulation of female puberty / Lomniczi, A.; Ojeda, S.R -- Normal variation in pubertal timing : genetic determinants in relation to growth and adiposity / Willemsen, R.H.; Dunger, D.B -- Genetics of hypogonadotropic hypogonadism / Topaloglu, A.K.; Kotan, L.D -- Sexual precocity : genetic bases of central precocious puberty and autonomous gonadal activation / Macedo, D.B.; Silveira, L.F.G.; Bessa, D.S.; Brito, V.N.; Latronico, A.C -- Congenital hypogonadotropic hypogonadism : a trait shared by several complex neurodevelopmental disorders / de Roux, N.; Carel, J.-C.; Léger, J. (Paris) -- Animal modeling of early programming and disruption of pubertal maturation / Castellano, J.M.; Tena-Sempere, M -- Contemporary trends in onset and completion of puberty, gain in height and adiposity / Biro, F.M.; Kiess, W -- Consequences of early life programing by genetic and environmental influences : a synthesis regarding pubertal timing / Roth, C.L.; DiVall, S -- Nutritional disorders and pubertal disorders / Muñoz-Calvo, M.T.; Argente, J -- Current changes in pubertal timing : revised vision in relation with environmental factors including endocrine disruptors / Parent, A.-S.; Franssen, D.; Fudvoye, J.; Pinson, A.; Bourguignon, J.-P -- Sex steroid and gonadotropin treatment in male delayed puberty / Howard, S.; Dunkel, L -- Sex steroid replacement therapy in female hypogonadism from childhood to young adulthood / Norjavaara, E.; Ankarberg-Lindgren, C.; Kriström, B -- Gonadotropin-releasing hormone agonist treatment in sexual precocity / Pienkowski, C.; Tauber, M -- Treatment of peripheral precocious puberty / Schoelwer, M.; Eugster, E.A -- Consultation for disordered puberty : what do adolescent medicine patients teach us? / Michaud, P.-A.; Ambresin, A.-E.
  • 2007 Springer
    edited by Robert B. Greifinger ; deputy editors, Joseph Bick, Joe Goldenson.
    Thirty years since Estelle v. Gamble: looking forward, not wayward / Robert B. Greifinger -- Impact of incarceration on community public safety and public health / Todd R. Clear -- Litigating for better medical care / Jon Wool -- Accommodating disabilities in jails and prisons / R. Samuel Paz -- Growing older: challenges of prison and reentry for the aging population / Brie Williams, Rita Abraldes -- International public health and corrections: models of care and harm minimization / Michael Levy -- The medicalization of execution: lethal injection in the United States / Mark Heath -- HIV and viral hepatitis in corrections: a public health opportunity / Joseph A. Bick -- Prevention of viral hepatitis / Cindy Weinbaum, Karen A. Hennessey -- HIV prevention: behavioral interventions in correctional settings / Barry Zack -- Prevention and control of tuberculosis in correctional facilities / Farah M. Parvez -- Controlling chlamydia, gonorrhea, and syphilis through targeted screening and treatment in correctional settings / Charlotte K. Kent, Gail A. Bolan -- Health promotion in jails and prisons: an alternative paradigm for correctional health services / Megha Ramaswamy, Nicholas Freudenberg -- Screening for public purpose: promoting an evidence-based approach to screening of inmates to improve the public health / Joshua D. Lee, Marshall W. Fordyce, Josiah D. Rich -- Written health informational needs for reentry / Jeff Mellow -- Reducing inmate suicides through the mortality review process / Lindsay M. Hayes -- Blinders to comprehensive psychiatric diagnosis in the correctional system / Richard L. Grant -- Juvenile corrections and public health collaborations: opportunities for improved health outcomes / Michelle Staples-Horne, Kaiyti Duffy, Michele T. Rorie -- Female prisoners and the case for gender-specific treatment and reentry programs / Andrea F. Balis -- Building the case for oral health care for prisoners: presenting the evidence and calling for justice / Henrie M. Treadwell, Mary E. Northridge, Traci N. Bethea -- Treatment of mental illness in correctional settings / Raymond F. Patterson, Robert B. Greifinger -- Treatment and reentry approaches for offenders with co-occurring disorders / Roger H. Peters, Nicole M. Bekman -- Pharmacological treatment of substance abuse in correctional facilities: prospects and barriers to expanding access to evidence-based therapy / R. Douglas Bruce, Duncan Smith-Rohrberg, Frederick L. Altice -- Health research behind bars: a brief guide to research in jails and prisons / Nicholas Freudenberg -- Reentry experiences of men with health problems / Christy A. Visher, Kamala Mallik-Kane -- Providing transition and outpatient services to the mentally ill released from correctional institutions / Steven K. Huge -- Sexual predators: diversion, civil commitment, community reintegration, challenges, and opportunities / Karen Terry -- Electronic health records systems and continuity of care / Ralph P. Woodward -- Community health and public health collaborations / Thomas Lincoln, John R. Miles, Steve Scheibel -- Improving the care for HIV-infected prisoners: an integrated prison-release health model / Sandra A. Springer, Frederick L. Altice.
  • 2009
    World Health Organization.
    Status: Not Checked OutLane Catalog Record
  • 2016 Springer
    Md. Nazrul Islam, editor.
    Introduction -- Challenges to Health Service System in China: Institutional and financial reforms -- Food safety Challenges in China -- Challenge of Population Ageing on Health -- Integrating Chinese Medicine in public health: Contemporary trend and challenges -- State-Religion Partnership: Delivery of Eldercare in Asia -- Substance Abuse and Its Prevention and Treatment in Macao -- Development of Healthcare Social Work in China.
  • 2013 CRCnetBASE
    Jerome Goddard.
    "Increasing problems of emerging and re-emerging infectious diseases, brought about, at least in part, by vectors fueled by increased worldwide travel and commerce, make this a highly timely book for anyone in the public practice of medical and veterinary entomology, including entomologists, public health officials, and pest control technicians and managers. Employing a reader-friendly style with bulleted texts, scenarios, and case history boxes, it targets the major vectors and pests of medical and public health importance, addresses regulatory and academic medical entomology, and discusses disease vector control with worldwide application"--Provided by publisher.
  • 2006 Wellcome Trust
    edited by V. Berridge, D.A. Christie and E.M. Tansey.
  • 2014 Springer
    J.A. Magnuson, Paul C. Fu, Jr., editors.
    Part I. Context for Public Health Informatics -- 1. Introduction to Public Health Informatics / J.A. Magnuson and Patrick W. O'Carroll -- 2. History and Significance of Information Systems and Public Health / John R. Lumpkin and J.A. Magnuson -- 3. Context and Value of Biomedical and Health Informatics / William R. Hersh -- 4. Governmental and Legislative Context of Informatics / Margo Edmunds -- Part II. The Science of Public Health Informatics -- 5. Public Health Informatics Infrastructure / Brian E. Dixon and Shaun J. Grannis -- 6. Information Architecture / Dina Dickerson and Patricia Yao -- 7. Data Sources and Data Tools / Edward Mensah and Johanna L. Goderre -- 8. Public Health Information Standards / J.A. Magnuson, Riki Merrick, and James T. Case -- 9. Privacy, Confidentiality, and Security of Public Health Information / William A. Yasnoff -- 10. Electronic Health Records / Stephen P. Julien -- 11. Ethics, Information Technology, and Public Health: Duties and Challenges in Computational Epidemiology / Kenneth W. Goodman and Eric M. Meslin -- 12. Project Management and Public Health Informatics / James Aspevig -- 13. Evaluation for Public Health Informatics / Paul C. Fu, Jr., Herman Tolentino, and Laura H. Franzke -- Part III. Key Public Health Information Systems -- 14. Informatics in Disease Prevention and Epidemiology / Richard S. Hopkins and J.A. Magnuson -- 15. Informatics in Toxicology and Environmental Public Health / Edwin M. Kilbourne -- 16. Public Health Laboratories / Riki Merrick, Steven H. Hinrichs, and Michelle Meigs -- 17. The National Vital Statistics System / Charles J. Rothwell, Mary Anne Freedman, and James A. Weed -- 18. Risk Factor Information Systems / Alan Tomines -- 19. Setting national Policies and Standards for Immunization Information Systems / Nedra Y. Garrett -- Part IV. New Challenges and Emerging Solutions -- 20. New Means of Data Collection and Accessibility / I. Charie Faught, James Aspevig, and Rita Spear -- 21. Geographic Information Systems / Carol L. Hanchette -- 22. Public Health Informatics and Health Information Exchange / J.A. Magnuson and Paul C. Fu, Jr. -- 23. Decision Support and Expert Systems in Public Health / William A. Yasnoff and Perry L. Miller -- 24. Delivery of Preventive Medicine in Primary Care / Paul C. Fu, Jr., Alan Tomines, and Larry L. Dickey -- 25. Case-Based Learning in Public Health Informatics / Herman Tolentino, Sridhar R. Papagari Sangareddy, Catherine Pepper, and J.A. Magnuson -- Part V. Case Studies: Information Systems and the Strata of Public Health -- 26. Local and Regional Public Health Informatics / Jeffrey M. Kriseman and Brian J. Labus -- 27. Public Health Informatics in High Population States: New York and Ohio / Geraldine S. Johnson, Guthrie S. Birkhead, Rachel Block, Shannon Kelley, James Coates, Bob Campbell, and Brian Fowler -- 28. State Public Health Informatics: Perspective from a Low Population State / James Aspevig -- 29. National Public Health Informatics, United States / Seth Foldy -- 30. Public Health Informatics in Canada / Lawrence E. Frisch, Elizabeth M. Borycki, Alyse Capron, Abla Mawudeku, and Ronald St. John -- 31. Perspectives on Global Public Health Informatics / Janise Richards, Gerry Douglas, and Hamish S.F. Fraser -- Part VI. Epilogue -- 32. Public Health Informatics: The Path Forward / J.A. Magnuson.
  • 2006
    Status: Not Checked OutLane Catalog Record
  • 2011 Springer
    Donald J. Lollar, Elena M. Andresen, editors.
    Introduction / Donald J. Lollar and Elena M. Andresen -- Epidemiology and biostatistics / Elena M. Andresen -- Social and behavioral dimensions of health / Paul Devereaux and Charlie Bullock -- Disability in the health services curriculum / Carol Tobias -- Environmental health and disability / Donald J. Lollar -- Disability and health inequity / Dennis G. Heaphy, Monika Mitra, and Erin D. Bouldin -- Disability and maternal and child health / Debbie Allen -- Aging, disability, and public health / John Crews -- Disability and international health / Mary Chamie -- Disability issues in health care ethics and law in the public health curriculum / Jerome E. Bickenbach -- Section 504 the Rehabilitation Act and the Americans with Disabilities Act in public health education / Dennis G. Heaphy.
  • 2013 ebrary
    Dru Bhattacharya.
    The role of law : agencies, legislators, courts, and the constitution -- The role of epidemiology and medicine : diagnosis, prevention, control, and evaluation -- The role of economics : theories, modeling, and evaluation -- The role of politics : players, processes, and power -- The role of ethics : historical, contemporary, and future perspectives -- HIV criminalization -- Clean water and mosquito control -- HPV vaccination -- SCHIP and children with special health care needs -- Overweight and obesity -- Breast cancer screening -- Medical transportation : local research focus -- Medical transportation : local practice focus -- Taxes, politics, and public health policy : a look back at the 2008 presidential campaign -- Supplemental nutrition assistance program and modifying behavior -- Medical readmissions and the Affordable Care Act -- Tobacco control and cessation programs -- Emergency preparedness and infectious diseases -- The research policy brief : a primer -- Letters to the editor : a primer.
  • 2009
    Tom LaTourrette, Lynn E. Davis, David R. Howell, Preethi R. Sama, David J. Dausey ; prepared for the Department of Health and Human Services.
    Public health emergencies may arise directly or indirectly from a wide variety of events, including emerging diseases, natural disasters, industrial accidents, and terrorist attacks. One area that has not been examined in much detail is public health emergency preparedness for incidents involving the release of chemical or radiological agents. As part of RAND's continuing research into public health emergency preparedness, this report characterizes the public health service's role in preparing for and responding to such incidents, describes practices in use by local public health departments, and identifies functional areas of public health emergency preparedness and response for chemical and radiological incidents that may warrant further practice development.
  • 2005 NAP
    William H. Hooke and Paul G. Rogers, editors ; Roundtable on Environmental Health Sciences, Research, and Medicine, Board on Health Sciences Policy, Institute of Medicine and Disasters Roundtable, National Research Council.
  • v. 1, 1973/76.
    Pauling, Linus.
    Status: Not Checked OutLane Catalog Record
  • 2006
    Warren S. Browner.
    Status: Not Checked OutLane Catalog Record
    Overview -- Title and abstract -- Introduction -- Methods -- Results -- Tables -- Figures -- Discussion -- References and electronic publishing -- Authorship -- Posters -- Oral presentations -- Choosing a journal and responding to reviews -- Suggestions for writing well.
  • NCBI Bookshelf
    [NCBI].
    PubMed quick start -- Searching PubMed -- Understanding your search results -- Displaying and sorting your search results -- Changing how search results are displayed -- Finding related resources for a citation -- Viewing your search history -- Displaying the search details -- Printing citations -- Saving and e-mailing results and searches -- My NCBI.
  • 2011
    Hoda (Hedi) Razavi.
    Congenital heart defects (CHDs) are structural abnormalities of the heart and the great vessels that affect approximately 1 of 100 children born. Pulmonary artery stenosis is an obstruction which leads to ventilation-perfusion mismatching, right ventricular hypertension, right heart failure and possibly death. These lesions may be difficult to manage, as physicians cannot know a priori whether a particular stenosis should be treated and what the optimal timing for intervention would be. The general purpose of this work has been to quantitatively characterize the developmental effects of a pulmonary artery stenosis on the hemodynamics and structure of the pulmonary arterial system in small animal models. To enable the study of pulmonary arterial hemodynamics, we introduce the application of phase-contrast magnetic resonance imaging (PCMRI) to the pulmonary arteries of rats and quantitatively describe the pulmonary hemodynamic changes that take place with normal postnatal development. We validate the in vivo flow measurements of PCMRI against echocardiography (ultrasound) and fluorescent microspheres and establish the MR technique as consistent and reliable. We describe pulmonary arterial growth trends to consist of a fast growth spurt until adolescence, followed by a continuous yet slower growth until adulthood and show that relative flow to each lung does not change throughout development. To enable the study of the three-dimensional structure of the pulmonary vasculature, we developed new arterial casting, high-resolution micro-Computed Tomography imaging and image analysis techniques that when applied to the normal development of the lung indicate a continual growth of small arterioles [less than]100[Mu]m in lumen size until adulthood. These two novel techniques when applied to the case of a unilateral pulmonary artery stenosis reveal an abrupt reduction of blood flow to the obstructed lung, and an abrupt increase for the contralateral lung. Changes in arterial distensibility relative to pulmonary flow indicate the loss of an initial compensatory mechanism that attempts to maintain the normal homeostatic state but fails at later stages of development. We find that the hypoperfused lung suffers from hypoplasia, as well as severe vascular growth abnormalities of arterial disorganization, loss of vessels, and enlargement of bronchial arteries that result in increased pulmonary vascular resistance. The contralateral lung also exhibits impaired vascular growth due to increased pulmonary flow and pressure. Despite being larger, this lung also suffers from a loss in vessels that under conditions of stress leads to substantial elevation of pulmonary arterial pressures. These results suggest that early intervention in patients with pulmonary artery stenosis may be of utmost importance in halting and reversing such disadvantageous vascular remodelings.
  • 2014 Springer
    Yener S. Erozan, Ibrahim Ramzy.
    The Essentials in Cytopathology book series fulfills the need for an easy-to-use and authoritative synopsis of site specific topics in cytopathology. These guide books fit into the lab coat pocket and are ideal for portability and quick reference. Each volume is heavily illustrated with a full color art program, while the text follows a user-friendly outline format. This new edition of Pulmonary Cytopathology is fully updated and expanded providing more detailed discussion of the role of new techniques such as EUS needle biopsy and specific issues of adequacy assessment. The section on subclassification of poorly-differentiated non-small cell carcinomas has been expanded to include accuracy of diagnosis in small samples, the new classification of adenocarcinoma and NSCC, currently-used ancillary techniques; i.e., immunohistochemistry, molecular/genetic techniques and therapeutic applications. Molecular techniques have been added as needed for targeted therapy. The text and illustrations have been expanded throughout.
  • 2009 Springer
    Yener S. Erozan, Ibrahim Ramzy.
  • 2016 Springer
    edited by Mieczyslaw Pokorski.
    Chapter 1. Adiponectin and Mortality in Smokers and Non-Smokers of the Ludwigshafen Risk and Cardiovascular Health (LURIC) Study, G.E. Delgado, R. Siekmeier, W. März, M.E. Kleber -- Chapter 2. Heart Rate Variability and Arrhythmic Burden in Pulmonary Hypertension, C. Witte, J.U. Meyer zur Heide genannt Meyer-Arend, R. Andrié, J.W. Schrickel, C. Hammerstingl, J.O. Schwab, G. Nickenig, D. Skowasch, C. Pizarro -- Chapter 3. Cardiac Vagal Control and Depressive Symptoms in Response to Negative Emotional Stress, I. Tonhajzerova, Z. Visnovcova, A. Mestanikova, A. Jurko, M. Mestanik -- Chapter 4. Effect of Simulated Microgravity and Lunar Gravity on Human Inspiratory Muscle Function: ?Selena-T? 2015 Study, M.O. Segizbaeva, N.P. Aleksandrova, Z.A. Donina, E.V. Baranova, V.P. Katuntsev, G.G. Tarasenkov, V.M. Baranov -- Chapter 5. Airway Evaluation with Multidetector Computed Tomography Post-Processing Methods in Asthmatic Patients, M. Patyk, A. Obojski , Ł. Gojny, B. Panaszek, U. Zaleska-Dorobisz -- Chapter 6. Genotyping of EGFR Mutations from Bronchial Cytological Specimens in Slovakian Lung Cancer Patients, K. Baluchova, M. Zahradnikova, P. Bakes, S. Trubacova, H. Novosadova, E. Halasova, I. Majer, P. Hlavcak -- Chapter 7. Antiinflammatory Effect of N-Acetylcysteine Combined with Exogenous Surfactant in Meconium-Induced Lung Injury, P. Mikolka, J. Kopincova, L. Tomcikova Mikusiakova, P. Kosutova, A. Calkovska, D. Mokra,- Chapter 8. Pertussis: History of the Disease and Current Prevention Failure, E. Kuchar, M. Karlikowska-Skwarnik, S. Han, A. Nitsch-Osuch -- Chapter 9. Awareness of Influenza and Attitude Toward Influenza Vaccination among Medical Students, A. Banaszkiewicz, E. Talarek, J. Śliwka, F. Kazubski, I. Małecka, J. Stryczyńska-Kazubska, W. Dziubak, E. Kuchar -- Chapter 10. Pathogens Causing Upper Respiratory Tract Infections in Outpatients, A. Jama-Kmiecik, M. Frej-Mądrzak, J. Sarowska, I. Choroszy-Król.
    Also available: Print – 2016
  • 2007
    by Paul D. Stein.
    Status: Not Checked OutLane Catalog Record
  • 2015 Springer
    Mieczyslaw Pokorski, editor.
    The book discusses new concepts and findings in the field of pulmonary function. This function is notably associated with spirometry and gas exchange at the lungs. The technique of spirometry, its clinical meaning, and reference values have all been refined over decades of its use. Although spirometry remains ancillary in diagnosis-making, it seems hardly replaceable in monitoring of lung disease progression and treatment efficacy. Pulmonary function goes far beyond spirometry. It encompasses interactions with the cardiovascular system, sleep disordered breathing, etiological factors like occupational bio aerosol exposure or cigarette smoke related issues. Pulmonary function may crumple in any respiratory ailment, the case in point being all too often respiratory tract infections. Chapters contribute to the latest thinking on molecular mechanisms underpinning pulmonary function, on patient care and attempt to keep up-to-date with current clinical and research progress. The book will be of interest to both clinicians and biomedical researchers.
    Also available: Print – 2015
  • 2012
    Jack Wanger.
    Status: Not Checked OutLane Catalog Record
    This edition covers the most commonly performed pulmonary function tests separated into individual chapters to allow a full overview of each test. It contains updated material including the latest guidelines and recommendations from the American Thoracic Society ... et al. Each chapter includes: Relevant Physiology; Pertinent Background Information; Technical Factors; Relevant Instrumentation; Respiratory Calculations; Patient Cases; Self-assessment Questions.
  • 2009 Springer
    Ali Altalag, Jeremy Road and Pearce Wilcox.
  • 2009
    edited by Marc Humbert, Joseph P. Lynch III.
    Status: Not Checked OutLane Catalog Record
  • 2008 Springer
    [edited] by Nicholas S. Hill, Harrison W. Farber.
  • 2016 Springer
    Bradley A. Maron, Roham T. Zamanian, Aaron B. Waxman, editors.
    Historical Perspective on the Classification and Nomenclature of Pulmonary Hypertension -- The Defining Characteristics of Pulmonary Arterial Hypertension -- Pulmonary Hypertension in Patients Without Pulmonary Arterial Hypertension -- Epidemiology of Pulmonary Hypertension: From Quaternary Referral Centre to the Community -- The Effects of Chronic Hypoxia on Inflammation and Pulmonary Vascular Function -- Genetics of Pulmonary Vascular Disease -- Novel Mechanisms of Disease: Network Biology and MicroRNA Signaling in Pulmonary Hypertension -- Pulmonary Hypertension as a Metabolic Disease -- Renin-Angiotensin-Aldosterone and other Neurohumoral Factors in the Pathogenesis of Pulmonary Hypertension -- Animal Models of Pulmonary Hypertension -- The Cardiopulmonary Hemodynamic Evaluation of Pulmonary Hypertension -- Advanced Imaging in Pulmonary Hypertension -- Assessing Disease State in the Pulmonary Vasculature in Clinical Practice and Research -- Biomarkers and other Methods for Assessing Patient Progress -- Pulmonary Circulatory -- Right Ventricular Uncoupling: New Insights into Pulmonary Hypertension Pathophysiology -- Contemporary Pharmacotherapies Involving Nitric Oxide, Prostacyclin, and Endothelin Receptor Signaling Pathways -- Determining the Optimal Approach to Initiating Oral, Inhaled, and Intravenous Therapies in Clinical Practice: Sequential Goal-Directed Therapy is Best -- Counterpoint: Determining the optimal approach to initiating oral, inhaled, and intravenous therapies in clinical practice: Maximal upfront therapy is best -- Surgery, Devices, Transplantation and Other Interventional Options for the Treatment of Advanced Pulmonary Hypertension -- Patient Registries in Pulmonary Arterial Hypertension: the Role of Survival Equations and Risk Calculators -- Support Care for the Pulmonary Hypertension Patient -- Special Considerations for the Pulmonary Hypertension Patient -- The Future of Pulmonary Hypertension.
  • 2015 Springer
    Mieczyslaw Pokorski, editor.
    The respiratory tract is a frequent target of infections caused by a wide range of organisms. The book provides reader-friendly information on aspects of pulmonary infections, including comprehensive accounts of bacterial and viral diseases, therapeutic approaches, molecular and classical culture-related techniques of diagnosis, and explaining the basic cell biological mechanism. The role of oxidative stress, both helpful in fighting invading pathogens and detrimental in yielding to infection is detailed as it is often undervalued and needs focus. The chapters encompass latest developments and applications in bacteriology and virology, preventive and therapeutic tips, and raise attention to implementation of proper antibiotic policies by medical institutions to decrease resistance to antimicrobials. The perennial problem of low influenza vaccination coverage rate is rationalized. The volume will be of interest to both clinicians and biomedical researchers engaged in this exciting field.
    Also available: Print – 2015
  • 2016 Springer
    Mieczyslaw Pokorski, editor.
    Prevalence of pulmonary infectins caused by atypical pathogens in non-HIV immunocompromised patients -- Effects of S-nitroso-N-acetyl-penicillamine (SNAP) on inflammation, lung tissue apoptosis and iNOS activity in a rabbit model of acute lung injury -- Combination therapy with budesonide and salmeterol in experimental allergic inflammation -- Monoclonal antibodies for the management of severe asthma -- Cough and arabinogalactan polysaccharide from the bark of Terminalia Arjuna -- Bronchodilator and anti-inflammatory action of theophylline in a model of ovalbumin-induced allergic inflammation -- Importance of social relationships in patients with chronic respiratory diseases -- The renin-angiotensin-aldosterone system in smokers and non-smokers of the Ludwigshafen risk and cardiovascular health (LURIC) study -- Electrodermal activity in adolescent depression -- Metagenomic analysis of cerebrospinal fluid from patients with multiple sclerosis -- Index.
    Also available: Print – 2016
  • 2011 Springer
    Élie Azoulay (editor).
    Part I. Preamble and Introduction -- 1. Managing Patients with Hematological Malignancies for 25 Years / Benoit Schlemmer -- 2. Pulmonary Involvement in Patients with Hematological Malignancies / Élie Azoulay -- 3. Respiratory Infections in Patients with Hematological Malignancies / Ayman O. Soubani -- Part II. Epidemiology -- 4. Epidemiology of Respiratory Events in Patients with HM (Not Including ICU) / Georg Maschmeyer -- 5. Epidemiology of Acute Respiratory Failure in Patients with HM (ICU Only) / Carlos Agustí, Carmen Lucena, and Antoni Torres -- 6. Noninfectious Lung Involvement in Patients with Hematological Malignancies (Excluding BMT) / Bernard Maitre -- 7. Noninfectious Pulmonary Involvement in Hematopoietic Stem Cell or Bone Marrow Transplant Recipients / Bekele Afessa -- 8. Are There Any Pulmonary Issues Specifically Related to Cord Blood Transplants? / Jonathan Gutman -- 9. Cardiovascular Complications of Cancer Therapeutics / Aarif Y. Khakoo and Callie S. Kwartler -- 10. Prophylaxis: Peace of Mind? / Benoit Guery and Karine Faure -- Part III. Diagnostic Strategy in HM Patients -- 11. How Type of Malignancy and Treatment Assist in the Etiological Diagnosis / Alexandre Boyer and Didier Gruson -- 12. Contribution of Radiology in Patients with Hematological Malignancies and Pulmonary Involvement / Claus Peter Heussel -- 13. Is There Still a Place for Transbronchial Lung Biopsy or Other Lung Biopsy Techniques? / Christophe Dooms and Vincent Ninane -- 14. The Increasing Role for Core Needle Biopsy of Pulmonary Lesions in Immunocompromised Patients / Cédric de Bazelaire, Raphael Calmon, Marion Chapelier, Amélie Pluvinage, and Eric de Kerviler -- 15. Minimally Invasive Diagnostic Strategy in Immunocompromised Patients with Pulmonary Infiltrates / Laurent Camous, Virginie Lemiale, Achille Kouatchet, David Schnell, Sandra de Miranda, and Élie Azoulay -- 16. Pleural Effusions and Thoracentesis in Patients with Hematological Malignancies / Michael G. Alexandrakis, Paschalis Steiropoulos, and Demosthenes Bouros -- 17. Diagnostic Yield of BAL Fluid Cytology in Hematologic Malignancies / Jean-François Bernaudin and Jocelyne Fleury-Feith -- 18. New Methods for Bacterial Diagnosis in Patients with Hematological Malignancies / Agnès Ferroni and Jean-Ralph Zahar -- 19. FDG-PET Imaging in Haematological Patients with Pulmonary Infiltrates / Tomohiko Yamane -- 20. What Has Been Learned from Postmortem Studies? / Stephen M. Pastores, Alina O. Dulu, and Shilpa A. DeSouza -- Part IV. Lung Infections in Patients with HM --21. Common Viral Pneumonia / David Schnell, Jérôme Legoff, and Élie Azoulay -- 22. Emerging Viral Infections / Oliver Schildgen -- 23. Cytomegalovirus Pneumonia in Patients with Hematologic Malignancies / Karen J. Vigil and Roy F. Chemaly -- 24. Herpes Simplex Virus Pneumonia in Patients with Hematologic Malignancies / Jharna N. Shah and Roy F. Chemaly -- 25. Pneumocystis Pneumonia in Non-AIDS Immunocompromised Patients / Élie Azoulay, Virginie Lemiale, Achille Kouatchet, François Vincent, Antoine Roux, Guillaume Bollée, and Patricia Roux -- 26. Diagnosis of Invasive Pulmonary Aspergillosis in Patients with Hematologic Diseases / Marie-Elisabeth Bougnoux, Fanny Lanternier, Emilie Catherinot, Felipe Suarez, and Olivier Lortholary -- 27. Emerging Fungal Infections / Marcia Garnica and Marcio Nucci -- 28. Candida Pneumonia in Patients with Hematological Neoplasia / Carlos Carvajal, Jordi Rello, and Jeffrey Lipman -- 29. Parasitic Lung Infections / Jean-François Timsit, Jean-Paul Brion, and Hervé Pelloux -- 30. Pulmonary Mycobacterial Infections in Patients with Hematological Malignancies / Khalid A. Al-Anazi and Asma M. Al-Jasser -- Part V. Noninfectious Pulmonary Involvement in Patients with HM -- 31. Pleuropulmonary Changes Induced by Drugs in Patients with Hematologic Diseases / Philippe Camus -- 32. Cardiovascular Complications of Cancer and Radiation Therapy / Callie S. Kwartler and Aarif Y. Khakoo -- 33. Diffuse Alveolar Hemorrhage in Hematopoietic Stem Cell Transplant Recipients and Patients with Hematologic Malignancy / Bekele Afessa -- 34. Venous Thromboembolism in Patients with Hematologic Malignancies / Tarek Sousou and Alok A. Khorana -- 35. Transfusion-Related Acute Lung Injury in Children with Hematological Malignancies / Rachel S. Bercovitz, J. Bradley Ball, Marguerite R. Kelher, and Christopher C. Silliman -- 36. Acute Respiratory Distress Syndrome (ARDS) in Neutropenic Patients / Mokart Djamel, Textoris Julien, Ettori Florence, Bruno Chetaille, and Blache Jean-Louis -- 37. Pulmonary Venoocclusive Disease Following Hematopoietic Stem Cell Transplantation / Matthew C. Bunte and Linda J. Burns -- 38. Radiation Pneumonitis / Miguel Gallego Díaz and Jordi Rello Condomines -- 39. Leukostasis, Infiltration and Pulmonary Lysis Syndrome Are the Three Patterns of Leukemic Pulmonary Infiltrates / François Vincent -- 40. Pulmonary MALT Lymphoma: Clinical, Molecular and Therapeutic Aspects / Marie Wislez, Raphael Borie, Catherine Thieblemont, Marie-France Carette, Martine Antoine, and Jacques Cadranel -- 41. ARDS During Neutropenia Recovery / Élie Azoulay, Eric Ezingeard, Choupi-Salomon Berckowski, and Michael Darmon -- 42. Fibrosing Alveolitis in Hematologic Malignancy Patients Undergoing Hematopoietic Cell Transplantation / Huda Salman, Kenneth R. Cooke, and Hillard M. Lazarus -- Part VI. Treatment and Difficult Decisions in Patients with HM and ARF -- 43. Antibiotic Therapy in Neutropenic Patients / Matthieu Legrand, Adeline Max, and Bertrand Gachot -- 44. Antifungal Therapy in Patients with Hematological Malignancies / Raoul Herbrecht and Yasmine Nivoix -- 45. Antiviral Agents in Patients with Hematological Malignancies and Acute Respiratory Failure / Michael Sandherr -- 46. Mechanical Ventilation in Patients with Hematological Malignancies / Márcio Soares, Jorge I.F. Salluh, and Pieter O. Depuydt -- 47. Optimizing Noninvasive Ventilation in Hematological Patients with Acute Respiratory Failure / Gilles Hilbert -- 48. Noninvasive Ventilation to Ensure the Safety of Fiberoptic Bronchoscopy / Massimo Antonelli, Giuseppe Bello, and Riccardo Maviglia -- 49. NIV Outside the ICU / Stefano Nava and Sebastiano Mercadante -- 50. Palliative Noninvasive Mechanical Ventilation in Patients with Hematological Malignancies / Anne-Pascale Meert, Thierry Berghmans, and Jean-Paul Sculier -- 51. Acute Kidney Injury in Cancer Patients / Michael Darmon, Laurent Camous, Camille Devanlay, Emmanuel Canet, Benoit Schlemmer, and Fabrice Zeni -- 52. Septic Shock / David Grimaldi and Frédéric Pène -- 53. Prognostic Factors for Mortality in the Critically Ill Cancer Patient / Kathleen N.S. Cathcart and Jeffrey S. Groeger -- 54. Managing Critically Ill Cancer Patients: Another Medical Success Story / Élie Azoulay, Marcio Soares, Michael Darmon, Dominique Benoit, Stephen Pastores, and Bekele Afessa -- 55. Palliative Care and Dyspnea Management in Patients with Hematological Malignancies and Acute Respiratory Failure / Amy P. Abernethy, Jane L. Wheeler, and David C. Currow -- 56. End-of-Life Decisions in Cancer Patients / Lieve Van den Block, Agnes van der Heide, and Luc Deliens -- Part VII. Pearls That You Should be Aware Of -- 57. An Unexpected Diagnosis of Pulmonary Tuberculosis / Virginie Lemiale, A. Seguin, and Élie Azoulay -- 58. Respiratory Symptoms Occurring 4 Months After Allogeneic Hematopoietic Stem Cell Transplantation / Anne Bergeron, Séverine Feuillet, Véronique Meignin, Patricia Ribaud, and Abdellatif Tazi -- 59. Pulmonary Complications of Chronic Lymphocytic Leukemia / Melhem Solh and Punit Wadhwa -- 60. Clinical Pearls: Pulmonary Veno-occlusive Disease / Jonathan Gutman -- 61. Cytarabine-Induced Pulmonary Toxicity in Leukemic Patients / Fabio Forghieri, Leonardo Potenza, Monica Morselli, Monica Maccaferri, Giuseppe Torelli, and Mario Luppi -- 62. Histoplasmosis in a Patient with Chronic Myelogenous Leukemia / Vincent Peigne, Benoît Schlemmer, and Olivier Lortholary -- 63. Pulmonary Toxicity of Imatinib and Other BCR-ABL Tyrosine Kinase Inhibitors / François Vincent -- 64. Rituximab-Related Pulmonary Toxicity / Yair Herishanu, Chava Perry, and Aaron Polliack -- 65. Cardiogenic Causes of Respiratory Failure in Patients with Hematological Malignancies / Julien Maizel, Berengere Gruson, Jean-Pierre Marolleau, and Michel Slama -- 66. Pulmonary Alveolar Proteinosis / François Vincent, H. Tandjaoui, and P.Y. Brillet -- 67. Pneumocystis jiroveci Pneumonia in a Patient with Diffuse Large B-Cell Lymphoma / Hung Chang and Lee-Yung Shih -- 68. Pulmonary Infiltration in Anaplastic T-Cell Lymphoma / Christophe Cracco, Julien Mayaux, Sylvain Choquet, Catherine Beigelman, and Frédéric Charlotte -- 69. A Rapidly Reversible Cause of Pulmonary Embolism / Sophie Georgin-Lavialle, Élie Azoulay, Fabrice Zeni, and Michael Darmon -- 70. Hairy Cell Leukemia with Pulmonary Infiltrates / Virginie Lemiale, Véronique Meignin, and Élie Azoulay -- 71. Trichosporon asahii Infection in a Neutropenic Patient / Djamel Mokart, Antoine Sannini, Jean-Paul Brun, Laurent Chow-chine, and Jean-Louis Blache -- Part VIII. Post Face -- 72. Who Is This Book for? Reserved to Highly Specialized Teams? / Laurent Brochard -- 73. Pulmonary Involvement in Patients with Hematological Malignancies: And Now? / Patricia Ribaud and Gérard Socié.
  • 2009 ClinicalKey
    [edited by] Nelson L. Turcios, Robert J. Fink.
    The first comprehensive, practical book strictly focused on diagnosing and treating the full spectrum of respiratory complications of non-pulmonary diseases. Pediatric pulmonologists and other expert specialists present their up-to-date and balanced perspectives on new approaches to therapy and recent advances on everything from HIV/AIDS and transplantation to postoperative complications. The contributors are some of the most distinguished and recognizable physicians in their fields giving you the benefit of accumulated insight and experience.
  • 2014 Springer
    Paul F. Dellaripa, Aryeh Fischer, Kevin R. Flaherty, editors.
    "The spectrum of systemic rheumatologic disease (often termed connective tissue disease) is characterized by autoimmune-mediated organ dysfunction, and the lungs are a frequent target. There are numerous pulmonary manifestations associated with connective tissue diseases, and all patients with rheumatologic disease are at risk of developing associated lung disease. Pulmonary Manifestations of Rheumatic Disease covers the comprehensive management of rheumatologic lung disease, which requires a multi-disciplinary approach and is optimized by active engagement by rheumatologists working closely with pulmonologists and other specialists. The book offers a practical reference using a case-based approach for practicing clinicians in the ongoing assessment and understanding of rheumatologic lung disease, and presents the science and pathophysiology underlying rheumatologic lung diseases. The first text of its kind specifically dedicated to describe diverse, commonplace, and challenging aspects of rheumatologic lung diseases, Pulmonary Manifestations of Rheumatic Disease serves as an invaluable tool for the practicing clinician."--Publisher's website.
  • 2012 CRCnetBASE
    edited by Neeraj Vij.
    This book explores engineered nanomaterials (ENM) pulmonary effects and familiarizes readers with unique aspects of nanomaterial application and research. Focusing on the diagnostic and therapeutic utilities of nanomaterials in different lung diseases, it discusses the novel applications of nanotechnology for the treatment of airway diseases such as asthma, allergy, chronic obstructive pulmonary diseases, cystic fibrosis, and lung cancer. In an attempt to synchronize the efforts of pulmonary biologists, chemists, and clinicians in developing novel nano-based tools for airway diseases, the book also discusses the strategies to overcome the pathophysiological and technical barriers.
  • 2008 ClinicalKey
    edited by Dani S. Zander, Carol F. Farver.
    This volume in the Foundations in Diagnostic Pathology Series packs today's most essential pulmonary pathology into a compact, high-yield format! It covers both common and rare neoplastic and non-neoplastic diseases of the lung and pleura and focuses primarily on diagnosis with correlations to clinical and radiographic characteristics. Its pragmatic, well-organized approach, abundant full-color illustrations, and at-a-glance boxes and tables make the information you need easy to access. Practical and affordable, this resource is ideal for study and review as well as everyday clinical practice! Detailed discussions on today₂s technologies help you select the best test for case evaluation. Chapters devoted to the techniques used in the assessment of pulmonary diseases, including immunohistochemistry, immunofluorescnece, and certain clinical laboratory tests offer you a better understanding of techniques and their application for the diagnosis of lung disease. Internationally recognized pathologists convey the most current information, keeping you on the cusp of your field. More than 800 photomicrographs and gross photographs--most in full color--present important pathologic features, enabling you to form a differential diagnosis and compare your findings with actual cases. Uses a consistent, user-friendly format, including at-a-glance boxes and tables for easy reference.
  • 2008
    John B. West.
    Status: Not Checked OutLane Catalog Record
    Ventilation -- Gas exchange -- Other tests -- Obstructive diseases -- Restrictive diseases -- Vascular diseases -- Environmental and other diseases -- Respiratory failure -- Oxygen therapy -- Mechanical ventilation.
  • 2013 AccessMedicine
    Michael G. Levitzky.
    1. Function & structure of the respiratory system -- 2. Mechanics of breathing -- 3. Alveolar ventilation -- 4. Blood flow to the lung -- 5. Ventilation-perfusion relationships -- 6. Diffusion of gases and interpretation of pulmonary function tests -- 7. Transport of oxygen & carbon dioxide in the blood -- 8. Acid-base balance -- 9. Control of breathing -- 10. Nonrespiratory functions of the lung -- 11. The Respiratory system under stress.
  • 2007
    Michael G. Levitzky.
    Status: Not Checked OutLane Catalog Record
  • 2009 Springer
    edited by Ghada Bourjeily, Karen Rosene-Montella.
    Normal pregnancy -- Physiological transition from fetal to neonatal life in pregnancy -- Respiratory physiology in pregnancy -- High altitude, chronic hypoxia, and pregnancy -- Sleep physiology in pregnancy -- General management principles in pregnancy -- Diagnostic imaging in pregnancy -- Prescribing in pregnancy and lactation -- Monitoring fetal well-being in the critical care setting -- Anesthetic considerations in pregnant patients with pulmonary disorders -- Pulmonary disorders in pregnancy -- Obstructive sleep apnea in pregnancy -- Restless legs syndrome and periodic limb movement disorder in pregnancy -- Asthma in pregnancy -- Tuberculosis and pregnancy -- Pneumonia in the pregnant patient -- Chronic pulmonary disease and pregnancy -- Neuromuscular and chest wall diseases in pregnancy -- Pregnancy and the cystic fibrosis patient -- Pulmonary complications of collagen vascular disease in pregnancy -- Venous thromboembolism in pregnancy -- Pulmonary arterial hypertension in pregnancy -- Pulmonary procedures during pregnancy -- Critical illness in pregnancy -- Acute lung injury in pregnancy -- Airway management and mechanical ventilation in pregnancy.
  • 2014 Springer
    Marc A. Judson, editor.
    Pulmonary Sarcoidosis: A Guide for the Practicing Clinician is a valuable resource for clinicians of varied disciplines concerning the care of the sarcoidosis patient. Sarcoidosis is a multi-system disorder and represents a major challenge to physicians. Although any organ may be involved with sarcoidosis, the lung is the most common organ affected. Chapters are written by distinguished authors who have extensive experience in caring for these patients. Detailed figures and tables are provided to guide the practicing clinician through all aspects of the condition, from clinical manifestations to treatment options. Pulmonary Sarcoidosis: A Guide for the Practicing Clinician is fully comprehensive and evidence-based and will be an essential addition to the bookshelves of all whose practice involves the care and treatment of patients with sarcoidosis.
  • 2006
    edited by Jess Mandel, Darren Taichman.
    Status: Not Checked OutLane Catalog Record
  • 2012 Karger
    volume editors, Marc Humbert, Rogerio Souza, Gérald Simonneau.
    Updated clinical classification of pulmonary hypertension -- Pathology of pulmonary arterial hypertension -- Invasive rest and exercise hemodynamics in the modern management of pulmonary vascular disease: an expanding role in the future -- Exercise testing in pulmonary arterial hypertension -- Noninvasive exploration of the pulmonary circulation and the right heart -- Biomarkers in pulmonary arterial hypertension -- Genetics of pulmonary arterial hypertension and the concept of heritable pulmonary arterial hypertension -- Drug- and toxin-induced pulmonary arterial hypertension -- Idiopathic pulmonary arterial hypertension and its prognosis in the modern management era in developed and developing countries -- Pulmonary arterial hypertension complicating connective tissue disorders -- Pulmonary arterial hypertension and HIV and other viral infections -- Portopulmonary hypertension and hepatopulmonary syndrome -- Pulmonary hypertension in congenital heart diseases -- Pulmonary hypertension in sickle cell disease -- Schistosomiasis and pulmonary hypertension -- Pulmonary veno-occlusive disease -- Pulmonary hypertension and left heart disease -- Pulmonary hypertension in chronic obstructive pulmonary disease -- Pulmonary hypertension complicating interstitial and granulomatous lung diseases -- High-altitude pulmonary hypertension -- Acute pulmonary venous thromboembolic disease -- Anticaogulation for venous thromboembolism in the modern management era -- Chronic thromboembolic pulmonary hypertension -- Medical treatment of pulmonary arterial hypertension -- Lung transplantation and role for novel extracorporeal support in pulmonary hypertension -- Artrial septostomy -- Pulmonary vascular disorders in hereditary hemorrhagic telangiectasia -- Future perspectives in pulmonary arterial hypertension.
  • 2012 Springer
    Paolo Salvi ; [translated by Nicoletta Abbondanza].
    Introduction -- Mean Arterial Pressure -- Pulse Pressure -- Evaluation of the Mechanical Properties of Large Arteries -- Central Arterial Blood Pressure -- Pulse Wave Analysis -- Central Blood Pressure and Cardiovascular Risk -- Noninvasive Measurement of Central Blood Pressure -- Instruments for Pulse Wave Analysis and Measurement of Pulse Wave Velocity -- Pulse Wave Velocity and Pulse Wave Analysis in Experimental Animals.
  • 2011
    John Warner Fathman.
    Hematopoietic stem cells (HSC) are at the top of hematopoietic hierarchy and give rise to functional effector cells through a succession of increasingly committed downstream progenitor cells. Based upon data obtained from transplantation and in vitro culture experiments we have constructed a model of hematopoietic development by which small numbers of HSCs generate large numbers of mature effector cells through the successive amplification of transiently proliferating progenitor cells downstream of HSCs. HSCs have been extensively characterized based on their cell surface phenotype and functional activities during transplantation assays. Here we describe a marker, CD11a, which allows for the enhanced purification of murine HSCs. We have shown that upregulation of CD11a on HSCs denotes the loss of self-renewal potential, and that CD11a-Slam+CD34-c-kit+Sca1+Lin- are the true HSC. Natural killer (NK) cells develop in the bone marrow and are known to gradually acquire the ability to eliminate infected and malignant cells, yet the cellular stages of NK lineage commitment and maturation are incompletely understood. Using 12-color flow cytometry, we identified a novel NK-committed progenitor (pre-NKP) that is a developmental intermediate between the upstream common lymphoid progenitor (CLP) and the downstream NKP, previously assumed to represent the first stage of NK lineage commitment. Taken together, our data provide a high-resolution in vivo analysis of the earliest steps of NK cell commitment and maturation.
  • 2009
    Andreas Hasso Ehrensberger.
    The disassembly of promoter nucleosomes is a requirement for the activation of eukaryotic genes. It renders the DNA accessible to the transcriptional machinery and primes it for the synthesis of messenger RNA by RNA Polymerase II. Promoter selection is achieved by the activator, a sequence-specific DNA binding protein that recognizes the promoter and recruits the nucleosome disassembly factor. The goals of this project were: 1. To establish an assay that recapitulates promoter-specific and activator-dependent nucleosome disassembly in vitro as it has been observed in vivo. 2. To identify the nucleosome disassembly factor responsible for this activity by purifying it from fractionated crude yeast extract and testing individual fractions using the aforementioned assay. As a model system, I chose the PHO5 promoter from yeast. Its activator, Pho4, is shuttled into the nucleus in response to phosphate starvation, where it binds to the promoter and triggers the disassembly of three nucleosomes. This process has been postulated to require an ATP-dependent nucleosome disassembly factor that is recruited via the activation domain of Pho4. Previous genetic and biochemical experiments have failed at revealing the identity of such a factor. I discovered that an activator-dependent nucleosome disassembly activity can be detected in vitro, that it depends on the activation domain of Pho4, and that it exhibits strong preference for the PHO5 promoter over its open-reading frame. As expected, the activity requires ATP. I developed a chromatographic fractionation protocol through which the activity was purified to a high degree of homogeneity. Mass spectrometry revealed the chromatin-remodeling complex Chd1 and the transcription elongation factor Sub1 to coelute with the activity. Purified Chd1 exhibited nucleosome disassembly activity and a chd1 deletion strain constitutively activated at PHO5 lacked expression of PHO5. These results pave the way for a further characterization of Chd1 in promoter-specific nucleosome disassembly and for the quest for additional stimulatory factors involved in this fundamental biochemical process.
  • ScienceDirect
    edited by Patricia A. Hoffee, Mary Ellen Jones.
    Also available: Print – 1978
  • 2011 Springer
    Maryse Picher, editor-in-chief ; Richard C. Boucher, editor.
    Nucleotide release by airway epithelia / E.R. Lazarowski ... [et al.] -- Mechanisms regulating airway nucleotides / M. Picher -- Computational model for the regulation of extracellular ATP and adenosine in airway epithelia / G.J. Garcia ... [et al.] -- Regulation of airway nucleotides in chronic lung diseases / C.R. Esther, Jr., N.E. Alexis and M. Picher -- Nucleotide-mediated airway clearance / A. Schmid ... [et al.] -- Purinergic signaling in wound healing and airway remodeling / A. van der Vliet and P.F. Bove -- Purinergic regulation of airway inflammation / M. Koeppen ... [et al.] -- Animal models of airway diseases / L.F. Thompson, M. Picher and M.R. Blackburn -- Therapeutic applications / S. Tilley, J. Volmer and M. Picher.
  • 2012 Springer
    Geoffrey Burnstock, Alexej Verkhratsky.
    Introduction -- Early History of Purinergic Signalling -- Purinergic Cotransmission -- Mechanisms of ATP Release and Inactivation -- Receptors for Purines and Pyrimidines -- Evolution of Purinergic Signalling -- Peripheral Nervous System -- Purinergic Signalling in the Central Nervous System -- Sensory Nerves -- Special Senses -- Ontogeny of Purinergic Neurotransmission.
  • 2009
    Matthew Joseph Bundick.
    Emerging adulthood represents a critical phase for the development of purpose in life, yet little is known about the process through which young people become purposeful, or what the lasting benefits of such purposefulness might be. The present investigation explored four primary hypotheses though three interconnected studies. The first hypothesis, addressed in Study 1 using cross-sectional data, posited that purpose and meaningful engagement would be associated with psychological well-being. The second hypothesis proposed a mediational model, wherein the relationship between meaningful engagement and psychological well-being would be mediated by purpose; this hypothesis was tested first with cross-sectional data in Study 1 and again using longitudinal data in Study 2. Third, a moderation hypothesis was tested on the temporal relationship between purpose and psychological well-being, specifically that the relationship would be stronger for those high in self-transcendent life goals. Finally, Study 3 tested an intervention hypothesis to see whether engaging in deep reflection on and discussion about one's life goals can increase purpose and, consequently, psychological well-being. The results showed partial confirmation of the hypotheses. The cross-sectional analyses showed strong relations among meaningful engagement, purpose, and psychological well-being, and provided support for the proposed mediational model. However, the longitudinal analyses did not show significant relations among the constructs. The moderation hypothesis provided evidence that the path from purpose to well-being was stronger for those high on self-transcendent life goals, suggesting psychological benefits of pursuing purposes beyond oneself (but not self-oriented life goals). Finally, there was a significant positive effect of engaging in deep discussion and reflection on one's life goals, toward both increased purpose and increased psychological well-being. Implications of these findings for higher education in particular are discussed, and directions for future research are presented.
  • 2008 ClinicalKey
    [edited by] Steven Fagien.
    Demonstrates a wealth of new procedures and provides fresh approaches from new leading authorities representing the various aesthetic specialties, including from plastic surgery, oculoplastic surgery, and dermatology, and new illustrations that help to update and enhance operative skills. A a new bonus DVD includes intraoperative videos that demonstrates how to perform a variety of key techniques, step by step.
  • 2013 ebrary
    editors Susan Frampton, Patrick A. Charmel, Sara Guastello.
    "The Putting Patients First Field Guide: Global Lessons in Designing and Implementing Patient Centered Care is the ultimate real-world guide to how hospitals, long-term care communities and integrated health care systems around the world are operationalizing the fundamental dimensions of a patient-centered culture, including access to information, family involvement, healing environments, employee and physician engagement, patient advocacy and more. Edited by Susan Framption and Patrick Charmel of Planetree, a nonprofit consulting and research organization dedicated to patient centered care, the book represents a concrete pathway to patient-centered excellence, using lessons from organizations around the world. By featuring real life examples of providers from nearly every continent, this book will underscore the adaptability of a patient-centered approach to accommodate cultural nuances while addressing the universal desire for patients and family members across cultures for holistic health care experiences that promote humanity, partnership and transparency."-- Provided by publisher.
  • 2007
    World Health Organization.
    Status: Not Checked OutLane Catalog Record
  • 2007 Karger
    volume editors, J.C. Türp, C. Sommer, A. Hugger.
    Orofacial pain : a challenge and chance (not only) for dentistry / Turp, J.C., Hugger, A., Sommer, C. -- Characteristics of muscle nociception / Mense, S. -- Nociceptors of the joint with particular reference to silent nociceptors / Schaible, H.-G. -- Inflammatory mediators in temporomandibular joint pain / Kopp, S., Sommer, C. -- The role of reproductive hormones in orofacial pain / LeResche, L. -- Pathophysiology of orofacial pain / Sessle, B. -- Dental pain : pathophysiology and management / Khan, A.A., Hargreaves, K.M. -- Myofascial temporomandibular disorder pain : pathophysiology and management / Schindler, H.J., Svensson, P. -- Painful arthrogenous temporomandibular disorders : pathophysiology, diagnosis, management and prognosis / Steenks, M.H., Hugger, A., de Wijer, A. -- Neuralgic and idiopathic facial pain : pathophysiology and management / Sommer, C. -- Burning mouth syndrome : pathophysiology and management / Zakrzewska, J., Renton, T. -- Psychosocial impact of orofacial Pain / Dworkin, S.F. -- A rationale for the classification of orofacial pain / Woda, A. -- Orofacial pain: past and future / Greene, C.S. -- The end of an era: orofacial pain enters the genomic age : implications and opportunities for research and the care of patients / Stohler, C.S.
    Also available: Print – 2007
  • 2006 Springer Protocols
    edited by Sharon Marsh.
    The history of pyrosequencing / Pol Nyron -- Pyrosequencing applications / Sharon Marsh -- Web-based primer design software for genome-scale genotyping by pyrosequencing / Steven Ringquist ... [et al.] -- Pyrosequencing : a simple method for accurate genotyping / Cristi R. King and Tiffany Scott-Horton -- Universal primer applications for pyrosequencing / Dong-Chuan Guo and Dianna M. Milewicz -- Allele quantification and DNA pooling methods / Jonathon Wasson -- Multiplex pyrosequencing for DNA variation analysis / Pritesh Patel, Yih-Horng Shiao, and Paolo Fortina -- Analysis of gene-specific DNA methylation patterns by the pyrosequencing technology / Jørg Tost and Ivo Glynne Gut -- Detecting mutations that confer oxazolidinone resistance in gram-positive bacteria / Neil Woodford, Sarah E. North, and Matthew J. Ellington -- Pyrosequencing-based strategies for improved allele typing of HLA loci / Steven Ringquist ... [et al.] -- Pyrosequencing of phage display libraries for the identification of cell-specific targeting ligands / Ahad A. Rahim -- Gene copy number detection in animal studies / Gerli Pielberg and Leif Andersson -- Detection of allelic imbalance in gene expression using pyrosequencing / Hua Wang and Steven C. Elbein -- Pyrosequencing genotype storage techniques / Derek J. Van Booven.
  • 2005 ProQuest Safari
    edited by Alex Martelli, Anna Martelli Ravenscroft, and David Ascher.
  • 2006
    David M. Beazley.
    Status: Not Checked OutLane Catalog Record
  • 2010 CRCnetBASE
    Sebastian Bassi.
    I. PROGRAMMING. 1. Introduction -- 2. First Steps with Python -- 3. Basic Programming: Data Types -- 4. Programming: Flow Control -- 5. Dealing with Files -- 6. Code Modularizing -- 7. Error Handling -- 8. Introduction to Object Orienting Programming (OOP) -- 9. Regular Expressions --- II. BIOPYTHON. 10. Introduction to Biopython --- III. ADVANCED TOPICS. 11. Web Applications -- 12. XML -- 13. Python and Databases -- 14. Collaborative Development: Version Control --- IV. PYTHON RECIPES WITH COMMENTED SOURCE CODE. 15. Sequence Manipulation in Batch -- 16. Web Application for Filtering Vector Contamination -- 17. Searching for PCR Primers Using Primer3 -- 18. Calculating Melting Temperature from a Set of Primers -- 19. Filtering out Specific Fields from a Genbank File -- 20. Converting XML Blast File into HTML -- 21. Inferring Splicing Sites -- 22. DNA Mutations with Restrictions -- 23. Web Server for Multiple Alignment -- 24. Drawing Marker Positions Using Data Stored in a Database --- Appendixes. A. Python and Biopython Installation -- B. Selected Papers -- C. Included DVD: Virtual Machine Installation and Use -- D. Python Language Reference -- E. Answers to Odd-Numbered Questions -- F. Python Style Guide.
  • Noah Gift and Jeremy M. Jones.

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A repository of medical knowledge from internal medicine, cardiology, genetics, pharmacy, diagnosis and management, basic sciences, patient care, and more.

Continuously expanding, all databases in the repository contain the latest editions of selected medical titles.

MicroMedex: Premier pharmaceutical information source containing multiple databases and drug reference tools. Of particular value is DRUGDEX Evaluations, one of the most comprehensive drug sources available.DynaMed Plus is a clinical information resource used by physicians to answer clinical questions quickly and easily at the point of care. Topics are updated daily as new evidence becomes available.Scopus is the largest abstract and citation database of peer-reviewed literature: scientific journals, books and conference proceedings.A drug information resource containing: American Hospital Formulary System (AHFS), drug formulary for Lucile Packard Children's Hospital (LPCH) and Stanford Hospital & Clinics (SHC), Lexi-Drugs (adverse reactions, dosage and administration, mechanism of action, storage, use, and administration information), Lexi-Calc, Lexi-ID, Lexi-I.V. Compatibility (King Guide), Lexi-Interact, and Lexi-PALS.Cumulative Index to Nursing and Allied Health Literature (CINAHL) contains coverage of nursing and allied health literature.A knowledge database that provides access to topic reviews based on over 6000 clinically relevant articles. The evidence-based content, updated regularly, provides the latest practice guidelines in 59 medical specialtiesProvides critical assessments of systematic reviews compiled from a variety of medical journals.Selects from the biomedical literature original studies and systematic reviews that are immediately clinically relevant and then summarizes these articles in an enhanced abstract with expert commentary.

Multidisciplinary coverage of over 10,000 high-impact journals in the sciences, social sciences, and arts and humanities, as well as international proceedings coverage for over 120,000 conferences.

Includes cited reference searching, citation maps, and an analyze tool.

Features systematic reviews that summarize the effects of interventions and makes a determination whether the intervention is efficacious or not.

Cochrane reviews are created through a strict process of compiling and analyzing data from multiple randomized control trials to ensure comprehensiveness and reliability.

Provides systematic coverage of the psychological literature from the 1800s to the present through articles, book chapters and dissertations.BMJ Clinical Evidence. A clinical information tool built around systematic reviews summarizing the current state of knowledge about prevention and treatment of clinical conditions.PIER (Physicians' Information and Education Resource) is a Web-based decision-support tool designed for rapid point-of-care delivery of up-to-date, evidence-based guidance for primary care physicians.Cochrane Central Register of Controlled Trials (CENTRAL) provides access to 300,000 controlled trials that have been identified the Cochrane Collaboration.Provides drug information targeted for patients.A continually updating drug monograph.The National Guideline Clearinghouse (NGC): A comprehensive database of evidence-based clinical practice guidelines and related documents.MedlinePlus: A repository of health information from the National Library of Medicine. Links are from trusted sites. No advertising, no endorsement of commercial companies or productsLPCH CareNotes via MicroMedex: Patient education handouts customized by LPCH clinical staffMicromedex Lab Advisor: Evidence based laboratory test informationA drug database organized by generic name, trade name and drug class.LPCH / Stanford Hospital Formulary.A goldmine of trusted consumer health information from the world's largest medical library.A trusted source of expert advice for and about kids, providing the information necessary to help patients and parents understand their unique needs.Provides patient handouts from the American Academy of Family Physician.Access to the Stanford Health Library for patients.Lane provides access to over 5,000 eBooks many of which provide helpful background material that will prepare you to better tackle primary literature.

Largest, broadest eBook package; covers all sciences, as well as technology (including software), medicine, and humanities.

In addition to covering Wiley and Springer, MyiLibrary is also the only provider for Oxford and Cambridge University Press titles. No seat restrictions.

A collection of biomedical books that can be searched directly by concept, and linked to terms in PubMed abstracts.

A web-based, decision support system for infectious diseases, epidemiology, microbiology and antimicrobial chemotherapy. The database, updated weekly, currently includes 337 diseases, 224 countries, 1,147 microbial taxa and 306 antibacterial (-fungal, -parasitic, -viral) agents and vaccines.

Over 10,000 notes outline the status of specific infections within each country.

Large number of high quality software and database programming titles from O'Reilly. Other software titles are also available from Sams and Prentice Hall. Limited to 7 concurrent users.Vast collection of software and database programming titles from multiple publishers, including Microsoft Press.Largest provider of engineering-related eBooks; includes titles in computer science and biomedical engineering.Over 4,000 full-text e-books covering scientific and technical information from CRC Press and others. Many handbooks and single volume reference sources.Includes peer-reviewed life science and biomedical research protocols compiled from Methods in Molecular Biology, Methods in Molecular Medicine, Methods in Biotechnology, Methods in Pharmacology and Toxicology, Neuromethods, the Biomethods Handbook, the Proteomics Handbook, and Springer Laboratory Manuals.Contains full text access to selected biomedical and nursing books.

Provides online, full-text access to Springer's journal titles as well as journals from other publishers.

Subjects include: life sciences, chemical sciences, environmental sciences, geosciences, computer science, mathematics, medicine, physics and astronomy, engineering and economics. Also includes eBooks.

Collection of over 8 thousand fulltext titles in engineering, math, and basic and applied biomedical research. Coverage is from 1967 to the present.A library of ebooks on a wide array of topics, digitized and made available online in conjunction with the original publishers.

Stanford Medicine

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