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  • 1. Noninvasive Breast Cancer / Robert H. I. Andtbacka ... [et al.] -- 2. Invasive Breast Cancer / Jonathan S. Zager ... [et al.] -- 3. Melanoma / Timothy M. Pawlik and Jeffrey E. Gershenwald -- 4. Nonmelanoma Skin Cancer / Nestor F. Esnaola and Keith M. Heaton -- 5. Soft Tissue and Bone Sarcoma / Keith A. Delman and Janice N. Cormier -- 6. Cancer in the Head and Neck / Kenneth A. Newkirk and F. Christopher Holsinger -- 7. Thoracic Malignancies / Shanda H. Blackmon and Ara A. Vaporciyan -- 8. Esophageal Carcinoma / Alexander A. Parikh, Ara A. Vaporciyan, and Wayne L. Hofstetter -- 9. Gastric Cancer / Waddah B. Al-Refaie and Paul F. Mansfield -- 10. Small-Bowel Malignancies and Carcinoid Tumors / Keith D. Amos and Rosa F. Hwang -- 11. Cancer of the Colon, Rectum, and Anus / George J. Chang and Barry W. Feig -- 12. Hepatobiliary Cancers / Eugene A. Choi, Steven E. Rodgers, Syed A. Ahmad, and Eddie K. Abdalla -- 13. Pancreatic Adenocarcinoma / Rosa F. Hwang ... [et al.] -- 14. Pancreatic Endocrine Tumors and Multiple Endocrine Neoplasia / Jeffrey T. Lenert ... [et al.] -- 15. Adrenal Tumors / Ricardo J. Gonzalez and Jeffrey E. Lee -- 16. Carcinoma of the Thyroid and Parathyroid Glands / Keith D. Amos, Mouhammed A. Habra, and Nancy D. Perrier -- 17. Hematologic Malignancies and Splenic Tumors / Wayne A. I. Frederick ... [et al.] -- 18. Cancer of Unknown Primary Site / Gauri R. Varadhachary -- 19. Genitourinary Cancer / Christopher G. Wood and Colin P.N. Dinney -- 20. Gynecologic Cancers / Brian M. Slomovitz, Pamela T. Soliman, Judith K. Wolf -- 21. Oncologic Emergencies / Jeffrey D. Wayne and Richard J. Bold -- 22. Biologic Cancer Therapy / Daniel Albo, Thomas N. Wang, and George P. Tuszynski -- 23. Pharmacotherapy of Cancer / Judy L. Chase and Chad M. Barnett -- 24. Reconstructive Surgery in the Cancer Patient / Jules A. Feledy, Jr. Matthew M. Hanasono, and Geoffrey L. Robb -- Index.
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    Training and program development / Timothy Jang, Michael J. Lambert -- Equipment / William Scruggs, J. Christian Fox -- Physics and image artifacts / Corky Hecht, William Manson -- Ultrasound in prehospital and austere environments / William Heegaard -- Trauma / O. John Ma, James R. Mateer, Andrew W. Kirkpatrick -- Cardiac / Robert F. Reardon, Scott A. Joing -- Pulmonary / Lisa Mills, Fernando Silva -- Critical care / Robert Reardon, Gavin Budhram, and David Plummer -- Abdominal aortic aneurysm / Robert F. Reardon, Dave Plummer, Thomas Cook -- Hepatobiliary / Daniel Theodoro, Resa Lewiss -- General surgery / Masaaki Ogata -- Renal / Stuart Swadron, Dina Seif -- Testicular / Srikar Adhikari -- First trimester pregnancy / Robert F. Reardon, Scott A. Joing -- Second and third trimester pregnancy / Barry Knapp, Don Byars -- Gynecologic concepts / Michael J. Lambert, J. Christian Fox -- Deep venous thrombosis / Tom Constantino, Harry Goett, Michael Peterson -- Soft tissue / Andreas Dewitz -- Ocular / Matt Lyon, Dietrich Jehle -- Pediatric applications / Jason Fischer, Adam Sivitz, and Alyssa Abo -- Vascular access / John S. Rose, Aaron E. Bair, Aman K. Parikh -- Additional ultrasound-guided procedures / Andreas Dewitz ... [et al.].
  • Succinct guide for Windows users migrating to the Mac.
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  • Machine generated contents note: -- 1. Using R -- R for Machine Learning -- Downloading and Installing R -- IDEs and Text Editors -- Loading and Installing R Packages -- R Basics for Machine Learning -- Further Reading on R -- 2. Data Exploration -- Exploration versus Confirmation -- What Is Data? -- Inferring the Types of Columns in Your Data -- Inferring Meaning -- Numeric Summaries -- Means, Medians, and Modes -- Quantiles -- Standard Deviations and Variances -- Exploratory Data Visualization -- Visualizing the Relationships Between Columns -- 3. Classification: Spam Filtering -- This or That: Binary Classification -- Moving Gently into Conditional Probability -- Writing Our First Bayesian Spam Classifier -- Defining the Classifier and Testing It with Hard Ham -- Testing the Classifier Against All Email Types -- Improving the Results -- 4. Ranking: Priority Inbox -- How Do You Sort Something When You Don't Know the Order? -- Ordering Email Messages by Priority -- Contents note continued: Priority Features of Email -- Writing a Priority Inbox -- Functions for Extracting the Feature Set -- Creating a Weighting Scheme for Ranking -- Weighting from Email Thread Activity -- Training and Testing the Ranker -- 5. Regression: Predicting Page Views -- Introducing Regression -- The Baseline Model -- Regression Using Dummy Variables -- Linear Regression in a Nutshell -- Predicting Web Traffic -- Defining Correlation -- 6. Regularization: Text Regression -- Nonlinear Relationships Between Columns: Beyond Straight Lines -- Introducing Polynomial Regression -- Methods for Preventing Overfitting -- Preventing Overfitting with Regularization -- Text Regression -- Logistic Regression to the Rescue -- 7. Optimization: Breaking Codes -- Introduction to Optimization -- Ridge Regression -- Code Breaking as Optimization -- 8. PCA: Building a Market Index -- Unsupervised Learning -- 9. MDS: Visually Exploring US Senator Similarity -- Contents note continued: Clustering Based on Similarity -- A Brief Introduction to Distance Metrics and Multidirectional Scaling -- How Do US Senators Cluster? -- Analyzing US Senator Roll Call Data (101st--111th Congresses) -- 10. kNN: Recommendation Systems -- The k-Nearest Neighbors Algorithm -- R Package Installation Data -- 11. Analyzing Social Graphs -- Social Network Analysis -- Thinking Graphically -- Hacking Twitter Social Graph Data -- Working with the Google SocialGraph API -- Analyzing Twitter Networks -- Local Community Structure -- Visualizing the Clustered Twitter Network with Gephi -- Building Your Own "Who to Follow" Engine -- 12. Model Comparison -- SVMs: The Support Vector Machine -- Comparing Algorithms.
  • pt. 2, 2013 Springer
    pt. 3, 2013 Springer
  • Introduction -- Molecular machines -- The processes of living -- Molecules in cells: Escherichia coli -- A human cell: The advantages of compartments -- The human body: The advantages of specialization -- Life and death -- Viruses -- You and your molecules.
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    Approach to the patient -- History taking -- The general examination -- The skin, hair and nails -- The endocrine system -- The cardiovascular system -- The respiratory system -- The gastrointestinal system -- The renal system -- The reproductive system -- The nervous system -- The visual system -- The ear, nose and throat -- The musculoskeletal system -- Babies and children -- Assessment for sedation and anaesthesia -- The critically ill patient -- Confirming death.
  • This textbook sets out clearly and concisely how to evaluate symptoms and elicit relevant physical signs. It describes the practical skills which every clinician must acquire and develop in order to evolve diagnostic procedures and management strategies and plans. Highly Commended in the 2006 and 2010 BMA Medical Book Competitions, this Thirteenth Edition contains over 500 clinical photographs and diagrams to illustrate the text, with new topics added to make the book even more comprehensive. Included on the Student Consult site are the specially-recorded videos demonstrating many of the clinical examination routines described in the main text. New to this edition: A new section explicitly spells out how to demonstrate the techniques learned in the book in an OSCE and other formative and summative examinations. The text has been substantially rewritten with more on medically unexplained symptoms in the History Taking chapter and extended coverage of diabetes mellitus in the Endocrine System chapter.
  • Introduction: brief historical overview -- Distribution of MACPF/CDC proteins -- Evolution of the complement system -- Structural features of cholesterol dependent cytolysins and comparison to other MACPF-domain containing proteins -- Perfringolysin O structure and mechanism of pore formation as a paradigm for cholesterol-dependent cytolysins -- Structural biology of the membrane attack complex -- Membrane interactions and cellular effects of MACPF/CDC proteins -- The biology of pneumolysin -- Multifaceted activity of listeriolysin O, the cholesterol -dependent cytolysin of Listeria monocytogenes -- Perforin: a key pore-forming protein for immune control of viruses and cancer -- Perforin and human diseases -- The role of MACPF proteins in the biology of malaria and other apicomplexan parasites -- Chlamydial MACPF protien CT153 -- Fungal MACPF-like proteins and aegerolysins: bi-component pore-forming proteins? -- Fluorescence imaging of MACPF/CDC proteins: new techniques and their application.
  • Part 1. Classification, Opportunities and Challenges -- Classification of Anticancer Drugs Based on Therapeutic Targets -- Signal Transduction Pathways as Therapeutic Targets in Cancer Therapy -- Part 2. Polymer-Based Anticancer Prodrugs -- HPMA-Anticancer Drug Conjugates -- Poly-l-Glutamic Acid Anti-cancer Drug Conjugates -- Polysaccharide-Based Anticancer Prodrugs -- PEG-Anticancer Drugs -- Poly(ethylene glycol)-Protein, Peptide, and Enzyme Conjugates -- Part 3. Lipid-Based -- Anticancer Prodrugs -- Lipid-Based Anticancer Prodrugs -- Part 4. Antibody-Directed Cancer Therapy -- Antibody-Cytotoxic Compound Conjugates for Oncology -- Immunoconjugate Anticancer Therapeutics -- Antibody-Directed Enzyme Prodrug Therapy (ADEPT) for Cancer -- EGFR-Directed Monoclonal Antibodies -- The Biology of the HER Family and Her2/neu Directed-Antibody Therapy -- Anti-Vascular Endothelial Growth Factor Monoclonal Antibodies -- Monoclonal Antibody Therapy for Hematologic Malignancies -- Part 5. Anticancer Oligonucleotide Therapeutics -- Anticancer Oligonucleotides -- Part 6. Miscellaneous -- New Molecular Therapeutic Interventions: The Case of Breast Cancers.
  • Macromolecular crystallography protocols v. 1-2, 2006.
    Springer Protocols
    v. 2, 2006 Springer Protocols
    v. 1. A Generic Method for the Production of Recombinant Proteins in Escherichia coli Using a Dual Hexahistidine-Maltose-Binding Protein Affinity Tag / Joseph E. Tropea ... [et al.] -- Cloning, Production, and Purification of Proteins for a Medium-Scale Structural Genomics Project / Sophie Quevillon-Cheruel ... [et al.] -- Baculoviral Expression of an Integral Membrane Protein for Structural Studies / Dean R. Madden and Markus Safferling -- Protein Engineering / Sonia, Longhi, Francois Ferron, and Marie-Pierre Egloff -- Production of Selenomethionyl Proteins in Prokaryotic and Eukaryotic Expression Systems / Sylvie Doublié -- How to Use Dynamic Light Scattering to Improve the Likelihood of Growing Macromolecular Crystals / Gloria E. O. Borgstahl -- Screening and Optimization Methods for Nonautomated Crystallization Laboratories / Terese Bergfors -- Improving Marginal Crystals / Charles W. Carter, Jr. and Madeleine Riès-Kautt -- Optimization Techniques for Automation and High Throughput / Naomi E. Chayen -- Three-Dimensional Crystallization of Membrane Proteins / James Féthière -- Crystallization of Protein-DNA Complexes / Thomas Hollis -- Preparation and Crystallization of RNA / Barbara L. Golden -- Crystallization of RNA-Protein Complexes / Eiji Obayashi ... [et al.] -- Index. v. 2. Cryocrystallography of Macromolecules: Practice and Optimization / Elspeth Garman and Robin L. Owen -- Determination of Reaction Intermediate Structures in Heme Proteins / Kelvin Chu -- Annealing Macromolecular Crystals / B. Lief Hanson and Gerard J. Bunick -- First Analysis of Macromolecular Crystals: Biochemistry and X-Ray Diffraction / David Jeruzalmi -- X-Ray Data Collection from Macromolecular Crystals / Elspeth Garman and Robert M. Sweet -- Characterizing a Crystal from an Initial Native Dataset / Michael R. Sawaya -- Molecular Replacement / Eric A. Toth -- Phase Determination using Halide Ions / Miroslawa Dauter and Zbigniew Dauter -- The Same But Different: Isomorphous Methods for Phasing and High-Throughput Ligand Screening / Mark A. Rould -- Substructure Determination in Multiwavelength Anomalous Diffraction, Single Anomalous Diffraction, and Single Isomorphous Replacement with Anomalous Scattering Data Using Shake-and-Bake / G. David Smith, Christopher T. Lemke, and P. Lynne Howell -- Substructure Determination in Isomorphous Replacement and Anomalous Diffraction Experiments / Ralf W. Grosse-Kunstleve and Thomas R. Schneider -- Automated Structure Solution with autoSHARP / Clemens Vonrhein, Eric Blanc, Pietro Roversi, and Gérard Bricogne -- Introduction to Macromolecular Refinement / Dale E. Tronrud -- Quality Control and Validation / Gerard J. Kleywegt -- Crystallographic Software: A Sustainable Resource for the Community / Stephen J. Everse and Sylvie Doublié -- Index. v. 1. Preparation and crystallization of macromolecules -- v. 2. Structure determination.
  • Macromolecular crystallography. Part A-D pt. A-D, 1997-2003
    ScienceDirect
    pt. B, 1997 ScienceDirect
    pt. C, 2003 ScienceDirect
    pt. D, 2003 ScienceDirect
  • Developments in macromolecular drug delivery / Mattias Belting and Anders Wittrup -- Synthetic vs. natural/biodegradable polymers for delivery of shRNA-based cancer therapies / John S. Vorhies and John J. Nemunaitis -- siRNA and DNA transfer to cultured cells / Bagavathi Gopalakrishnan and Jon Wolff -- Poly ([beta]-amino esters) : procedures for synthesis and gene delivery / Jordan J. Green ... [et al.] -- Systemic delivery and pre-clinical evaluation of nanoparticles containing antisense oligonucleotides and siRNAs / Chuanbo Zhang ... [et al.] -- Peptide-based delivery of steric-block PNA oligonucleotides / Saïd Abes ... [et al.] -- Characterizing peptide-mediated DNA internalization in human cancer cells / Anders Wittrup and Mattias Belting -- Selection and characterization of antibodies from phage display libraries against internalizing membrane antigens / Johan Fransson and Carl A.K. Borrebaeck -- Artificial membrane models for the study of macromolecular delivery / Lena Mäler and Astrid Gräslund -- Enhanced delivery of macromolecules into cells by electroendocytosis / Alexander Barbul ... [et al.] -- In vitro systems for studying epithelial transport of macromolecules / Nicole Daum ... [et al.] -- Preparation of macromolecule-containing dry powders for pulmonary delivery / Kelly S. Kraft and Marshall Grant -- Macromolecular delivery across the blood-brain barrier / Kullervo Hynynen -- Positron emission tomography (PET) and macromolecular delivery in vivo / Ludwig G. Strauss and Antonia Dimitrakopoulou-Strauss.
  • Generation of retroviral macrophage cDNA expression libraries and functional screening for surface receptors / Georgia Schäfer and Gordon D. Brown -- Generation of murine growth factor-dependent long-term dendritic cell lines to investigate host-parasite interactions / Alessandra Mortellaro ... [et al.] -- Macrophage activation : classical vs. alternative / Andrea Classen, Jorge Lloberas, and Antonio Celada -- Analysis of macrophage phagocytosis : quantitative assays of phagosome formation and maturation using high-throughput florescence microscopy / Benjamin E. Steinberg and Sergio Grinstein -- Detection of activated Rab7 GTPase with an immobilized RILP probe / Jim Sun ... [et al.] -- Probing in vivo origins of mononuclear phagocytes by conditional ablation and reconstitution / Chen Varol, Limor Landsman, and Steffen Jung -- Multivalent protein probes for the identification and characterization of cognate cellular ligands for myeloid cell surface receptors / Hsi-Hsien Lin ... [et al.] -- Exploiting Fc chimaeric proteins for the identification of ligands specific for the mannose receptor / Luisa Martinez-Pomares -- The expression of exogenous genes in macrophages : obstacles and opportunities / Xia Zhang, Justin P. Edwards, and David M. Mosser -- Genetic modification of murine dendritic cells by RNA transfection / Maurizio Ceppi, Enrico Schmidt, and Philippe Pierre -- Recording phagosome maturation through the real-time, spectrofluorometric measurement of hydrolytic activities / Robin M. Yates, Albin Hermetter, and David G. Russell -- Derivation and characterization of murine alternatively activated (M2) macrophages / Victor W.H. Ho and Laura M. Sly -- Isolation and culture of human hematopoietic progenitors for studies of dendritic cell biology / Mattias Svensson -- Generation, culture, and flow-cytometric characterization of primary mouse macrophages / Ulrike Schleicher and Christian Bogdan -- Analyzing classical and alternative macrophage activation in macrophage/neutrophil-specific IL-4 receptor-alpha-deficient mice / Frank Brombacher ... [et al.] -- Analysis of matrix metalloproteinase secretion by macrophages / Paul T. Elkington, Justin A. Green, and Jon S. Friedland -- Identification of pathogen receptors on dendritic cells to understand their function and to identify new drug targets / Lot de Witte ... [et al.] -- Stable lentiviral vector-mediated gene silencing in human monocytic cell lines / Jimmy S. Lee and Neil E. Reiner -- Use of fluorescent probes to detect lipid signaling intermediates in macrophages / Vivan Kwok, Eric Vachon, and Gregory P. Downey -- Large-scale phagosome preparation / Adrien F. Vinet and Albert Descoteaux -- Coordinate regulation of sphingosine kinase and actin dynamics / Shankar S. Iyer and David J. Kusner.
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    Development, structure and function of the liver -- Basic mechanisms in hepatopathology -- Cellular and molecular diagnostic techniques -- Developmental abnormalities and liver disease in childhood -- Genetic and metabolic liver disease -- Alcoholic liver disease -- Non-alcoholic fatty liver disease -- Acute and chronic viral hepatitis -- Other viral and infectious diseases and HIV-related liver disease -- Autoimmune hepatitis -- Diseases of the bile ducts -- Diseases of the gallbladder -- Vascular disorders -- Hepatic injury due to drugs, chemicals and toxins -- Tumours and tumour-like lesions of the liver -- Transplantation pathology -- Liver pathology associated with diseases of other organs and systems.
  • 2011 ClinicalKey
    1. Anatomy, pathophysiology and basic mechanisms of disease / James M. Crawford and Alastair D. Burt -- 2. Cellular and molecular techniques / Pierre Bedossa and Valerie Paradis -- 3. Developmental abnormalities and liver disease in childhood / Bernard C. Portmann and Eve A. Roberts -- 4. Genetic and metabolic liver disease / Richard J. Thompson, Bernard C. Portmann and Eve A. Roberts -- 5. Disorders of iron overload / Alan C. Paterson and Antonello Pietrangelo -- 6. Fatty liver disease : alcoholic and non-alcoholic / Elizabeth M. Brunt, Brent A. Neuschwander-Tetri and Alastair D. Burt -- 7. Acute and chronic viral hepatitis / Neil D. Theise, Henry C. Bodenheimer Jr. and Linda D. Ferrell -- 8. Other viral and infectious diseases and HIV-related liver disease / Sebastian B. Lucas, Sherif R. Zaki and Bernard C. Portmann -- 9. Autoimmune hepatitis / M. Kay Washington and Michael P. Manns -- 10. Diseases of the bile ducts / Yasuni Nakanuma, Yoh Zen and Bernard C. Portmann -- 11. Diseases of the gallbladder / Jorge Albores-Saavedra and Arturo Angeles-Angeles --12. Vascular disorders / Ian R. Wanless and Weei-Yuarn Huang -- 13. Hepatic injury due to drugs, herbal compounds, chemicals and toxins / James H. Lewis and David E. Kleiner -- 14. Tumours and tumour-like lesions of the liver / Zachary D. Goodman, Luigi M. Terracciano and Aileen Wee -- 15. Transplantation pathology / Stefan G. Hübscher and Andrew D. Clouston -- 16. Systemic disease / Alberto Quaglia, Alastair D. Burt, Linda D. Ferrell, Bernard C. Portmann.
  • 1 Organization of the adult fovea -- 2 Immunology and age-related macular degeneration -- 3 Photoreceptor degeneration in aging and age-related maculopathy -- 4 Genes and age-related macular degeneration -- 5 Epidemiology of age-related macular degeneration -- 6 Prevalence and risk factors for age-related macular degeneration in China -- 7 Experimental models of macular degeneration -- 8 Transporters and oxidative stress in AMD -- 9 Photoreceptor stability and degeneration in mammalian retina: lessons from the edge -- 10 Clinical strategies for diagnosis and treatment of AMD: implications from research.
  • For many years diagnosing macular edema at an early stage has been a main difficulty. Recently, multiple and remarkable advances of modern imaging technologies which allow recognition of the main etiologies, have immensely improved its diagnosis and treatment. In this volume different patterns and etiologies of macular edema are described and the importance of preserving the photoreceptors at an early stage in order to retain center visual acuity is discussed. It brings together the most recent data and evidence-based medicine, and, on the other hand, the pathophysiological basis of macular edema and the different approaches for drug delivery to the posterior segment are presented. Recommendations for treatment procedures or different therapies have been carefully analyzed and considered prior to inclusion. 'Macular Edema - A Practical Approach' provides the ophthalmologist with a synthesis of knowledge to diagnose, to determine etiology, and to offer the patient viable treatment options for his benefit.
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    "When it comes to understanding and treating madness, distortions of research are not rare, misinterpretation of data is not isolated, and bogus claims of success are not voiced by isolated researchers seeking aggrandizement. This book's detailed analyses of coercion and community treatment, diagnosis, and psychopharmacology reveals that these characteristics of bad science are endemic, institutional, and protected in psychiatry. This is mad science. Mad Science argues that the fundamental claims of modern American psychiatry are not based on convincing research, but on misconceived, flawed, and distorted science. The authors address multiple paradoxes in American mental health, including the remaking of coercion into scientific psychiatric treatment in the community, the adoption of an unscientific diagnostic system that now controls the distribution of services, and how drug treatments have failed to improve the mental health outcome." -- Publisher's description.
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    No bughouse doctor -- The Perils of pus infection -- The Mecca of exodontia -- Selling the cure -- Fighting focal infection -- The End of the affair? -- An American abroad -- Making a medical career -- Cotton under the microscope -- Averting a scandal -- Showdown -- Playing for time -- The New Lister -- Betrayals -- Death in the trenches. Epilogue: Psychiatry and its discontents.
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    Growing up -- The beginning of an odyssey -- A plethora of theories -- The scrapie race -- Dr. America and the trembling cannibals -- The battle for tenure -- What's in a name? -- Lost in the Pacific fog -- The amyloid story -- Finding the gene -- Jousting with the press -- Deciphering human prion diseases -- What's in a shape? -- Turf battles -- Mad cow and other prion strains -- Stockholm -- The third judgment of Paris -- Epilogue : the quest for therapeutics.
  • Magnesium is an essential mineral which is required for growth and survival of humans. Since magnesium is a mineral and not synthesizable it must be obtained through dietary foods and/or supplements. Magnesium in Human Health and Disease reviews the benefits of magnesium supplementation to reach recommended intakes as well as provides new research that suggests how reaching levels above the recommended intakes can promote health and treat various diseases. Magnesium deficiency can cause low serum potassium and calcium levels, retention of sodium, and low circulating levels of regulatory hormones. These changes in nutrients cause neurological and muscular symptoms such as tremor and muscle spasms. Further magnesium deficiency causes loss of appetite, nausea, vomiting, personality changes and death from heart failure. Causes of magnesium deficiency include alcohol abuse, poorly controlled diabetes, excessive or chronic vomiting and/or diarrhea. Thus the effects of inadequate and deficient intakes or levels of magnesium is critical to health and are reviewed by the expert clinicians in this book. Magnesium in Human Health and Disease provides the most current research to support the potential benefits or lack thereof for normal and high supplementation with magnesium. Animal model research and early human trials are reviewed to document other disease states such as hypertension, cholesterol level, type 2 diabetes and cardiovascular disease that would benefit from increased magnesium.
  • Magnetic cell separation 2008
    ScienceDirect
  • How Magnetic Particle Imaging Works -- How to Build an MPI Scanner -- Prior to Reconstruction - The System Function -- From Data to Images: Reconstruction -- Special System Topologies -- Putting MPI to Use: Applications.
  • This innovative book presents the development and clinical applications of magnetic resonance elastography (MRE), a new MRI-based imaging technology for quantitatively assessing the mechanical properties of tissue. Many disease processes cause profound changes in mechanical characteristics of tissue, but these changes can be completely invisible in examinations with conventional imaging technologies. MRE provides unique tissue information and powerful new diagnostic capabilities. The book begins with an accessible overview of the basic technology underlying MRE. Successive chapters provide coverage of the use of MRE to assess organ systems, including liver, skeletal muscle, brain, lungs, heart, breast, spleen, and kidney. The book is edited by Sudhakar Venkatesh, MD, a leader in the clinical use of this technology, and Richard Ehman, MD, the inventor of MRE. Magnetic Resonance Elastography is a valuable resource for radiologists, residents, fellows, technologists, hepatologists and scientists.
  • Technical advances in musculoskeletal imaging -- Surface coil imaging -- The hip -- The knee -- The ankle and foot -- Entrapment neuropathies of the lower extremity -- Articular cartilage -- The shoulder -- The elbow -- The wrist and hand -- MR imaging of the fingers -- Entrapment neuropathies of the upper extremity -- Marrow imaging -- Bone and soft-tissue tumors.
  • This textbook is alone in focusing on the subject of cardiac magnetic resonance (CMR) imaging in pediatric and adult patients with congenital heart disease. The topic of congenital heart disease imaging is usually relegated to a single chapter in most general CMR texts. The expanding scope of CHD warrants a text dedicated to covering CHD and CMR imaging in detail. Our proposed book aims to be a comprehensive and authoritative text on this subject.
  • Part I. Histology and Normal Bone Marrow -- Histology of Normal Bone and Bone Marrow, and Their Main Disorders / Reiner Bartl -- MR Imaging of the Normal Bone Marrow and Normal Variants / Bruno C. Vande Berg, P. Omoumi, C. Galant, N. Michoux, and F. E. Lecouvet -- Part II. Bone Marrow Neoplasia -- Haematological Bone Marrow Malignancies / Sung Kim, Kathleen Carrigan, and Michael Mulligan -- MRI of Bone Metastases / Gerwin Paul Schmidt and Andrea Baur-Melnyk -- Multiple Myeloma / Andrea Baur-Melnyk and Melvin D'Anastasi -- MRI for Response Assessment in Oncologic Bone Marrow Lesions / F. Lecouvet, P. Omoumi, A. Larbi, B. Tombal, N. Michoux, B. Vande Berg, and J. Malghem -- Differentiation of Benign and Malignant Vertebral Compression Fractures / Andrea Baur-Melnyk and Tobias Geith -- Part III. Benign Processes Affecting the Bone Marrow -- Diseases of the Reticuloendothelial System / Robert Hemke and Mario Maas -- Anemias and Bone Marrow Insufficiency / Iris-Melanie Noebauer-Huhmann and Martin Uffmann -- Osteonecrosis and Bone Infarction / Anastasia Fotiadou and Apostolos Karantanas -- Bone Marrow Edema Syndrome / Alain Blum, Sophie Lecocq, Matthias Louis, and Pedro Teixeira -- Bone Marrow Changes in Acute and Chronic Trauma / Filip M. Vanhoenacker, Michiel Eyselbergs, and Annick Demeyere -- Infective Inflammatory Bone Disease / Klaus Bohndorf and Hassan Douis -- Non-Infective Inflammatory Bone Marrow Disease / Bernhard J. Tins and Victor N. Cassar-Pullicino -- Part IV. Technical Aspects in Bone Marrow Imaging -- Techniques for Diffusion and Perfusion Assessment in Bone-Marrow MRI / Olaf Dietrich -- Magnetic Resonance Imaging of the Bone Marrow Contrast Media for Bone Marrow Imaging / Daniel Golovko, Elizabeth Sutton, and Heike E. Daldrup-Link.
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  • This abundantly illustrated atlas of MR imaging of the knee documents normal anatomy and a wide range of pathologies. In addition to the high-quality images, essential clinical information is presented in bullet point lists and diagnostic tips are included to assist in differential diagnosis. Concise explanations and guidance are also provided on the MR pulse sequences suitable for imaging of the knee, with identification of potential artifacts. This book will be an invaluable asset for busy radiologists, from residents to consultants. It will be ideal for carrying at all times for use in daily reading sessions and is not intended as a reference to be read in the library or in non-clinical settings.
  • Part 1: Role of MRI in imaging the skeletal musculature: Value of Magnetic Resonance Imaging of the Skeletal Musculature from a clinical point of view -- Correlation of skeletal muscle anatomical to MRI and US findings -- Imaging the skeletal muscle {u2013} when to use MRI and when to use ultrasound -- Part 2: Modern MRI techniques for assessment of the skeletal musculature: Whole-body MRI for evaluation of the entire skeletal system -- Diffusion-weighted and diffusion-tensor imaging: Applications in skeletal muscles -- Assessment of skeletal muscle perfusion using MRI (DCE, ASL, BOLD) -- Skeletal muscle MR imaging beyond protons -- MR spectroscopy and spectroscopic imaging for evaluation of skeletal muscle metabolism: Basics and applications in metabolic myopathies -- Part 3: MRI in the diagnostic work-up of the skeletal musculature: MRI of muscle injuries, such as muscle strains -- MRI in neurogenic myopathies and muscle denervation -- MRI in muscle dystrophies and other myogenic myopathies -- MRI in inflammatory myopathies and autoimmune-mediated myositis -- MRI in muscular channelopathies and myotonias -- MRI in muscle tumours and tumours of the muscle sheaths.
  • From molecules to man: The dawn of a vitreous man / M. Modo and J.W. Bulte-Magnetic resonance safety / A. Simmons and K. Hakansson-Measuring the absolute water content of the brain using quantitative MRI / N.J. Shah, V. Ermer and A.M. Oros-Peusquens-Magnetic resonance relaxation and quantitative measurement in the brain / S.C. Deoni-Magnetic resonance brain image processing and arithmetic with FSL / W.R. Crum-Diffusion tensor imaging / D.K. Jones and A. Leemans-Manganese-enhanced magnetic resonance imaging (meMRI) / C.A. Massaad and R.G. Pautler-Sodium MRI / R. Ouwerkerk-MR spectroscopy and spectroscopic imaging of the brain / H. Zhu and P.B. Barker-Amide proton transfer imaging of the human brain / J. Zhou-High-field MRI of brain iron / J.H. Duyn-Magnetic resonance imaging-based mouse brain atlas and its applications / M. Aggarwal, J. Zhang and S. Mori-Cest MRI reporter genes / G. Liu, J.W. Bulte and A.A. Gilad-Longitudinal functional magnetic resonance imaging in animal models / A.C. Silva ... [et al.]-Combining EEG and fMRI / K. Mullinger and R. Bowtell-MR angiography and arterial spin labelling / D. Thomas and J. Wells-MRI phenotyping of genetically altered mice / J.P. Lerch, J.G. Sled and R.M. Henkelman-Gene targeting MRI: Nucleic acid-based imaging and applications / P.K. Liu and C.H. Liu-Molecular MRI approaches to the detection of cns inflammation / N.R. Sibson ... [et al.]-Brain redox imaging / K. Matsumoto ... [et al.]-Systems biology approach to imaging of neural stem cells / L.H. Ma ... [et al.]-MRI of transplanted neural stem cells / S.M. Berman, P. Walczak and J.W. Bulte-MRI of experimental gliomas / F. Thorsen-MRI in experimental stroke / T.Q. Duong-Non-invasive MR imaging of neurodegeneration in a rodent model of parkinson's disease / A.C. Vernon and M. Modo-Detecting amyloid-beta plaques in alzheimer's disease / C. Baltes ... [et al.]-Assessing subtle structural changes in alzheimer's disease patients / J.L. Whitwell and P. Vemuri-Pharmacological application of fMRI / M.A. Mehta and O.G. O'Daly-MRI of neuronal plasticity in rodent models / G. Pelled-MR-guided focused ultrasound for brain ablation and blood-brain barrier disruption / Y. Huang and K. Hynynen.
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    When twelve-year-old Gabe tries to hide his uncle's death from the local authorities, he is not prepared for what happens when this secret is discovered.
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    Section I. Introduction -- Chapter 1. A focused history of surgery -- Chapter 2. Preoperative and postoperative management -- Chapter 3. Endoscopy and endoscopic intervention -- Section II. Abdominal wall -- Chapter 4. Incisions, closures, and management of the abdominal wound -- Chapter 5. Hernias -- Chapter 6. Intestinal stomas -- Chapter 7. Abdominal abscess and enteric fistula -- Section III. Esophagus -- Chapter 8. Benign esophageal disorders -- Chapter 9. Cancer of the esophagus -- Chapter 10. Surgical procedures to resect and replace the esophagus -- Section IV. Stomach and duodenum -- Chapter 11. Benign gastric disorders -- Chapter 12. Ulcer complications (including Zollinger-Ellison Syndrome) -- Chapter 13. Stomach and duodenum: operative procedures -- Chapter1 4. Gastric adenocarcinoma -- Chapter 15. Gastrointestinal stromal tumors -- Chapter 16. Morbid obesity and operations for obesity -- Section V. Small intestine and colon -- Chapter 17. Bowel obstruction -- Chapter 18. Diverticular disease of the colon -- Chapter 19. Crohn's disease -- Chapter 20. Ulcerative colitis -- Chapter 21. Appendix -- Chapter 22. Tumors of the small intestine -- Chapter 23. Tumors of the colon -- Section VI. Rectum and anus -- Chapter 24. Benign disorders of the anorectum (pelvic floor, fissures, hemorrhoids, fistulas) -- Chapter 25. Cancer of the rectum -- Chapter 26. Cancer of the anus -- Chapter 27. Complications following anorectal surgery -- Section VII. Liver -- Chapter 28. Hepatic abscess and cystic disease of the liver -- Chapter 29. Benign and malignant primary liver neoplasms -- Chapter 30. Colorectal metastasis (Re -- section, pumps, RF ablation, and cryoablation) -- Chapter 31. Portal hypertension -- Section VIII. Gallbladder and bile ducts -- Chapter 32. Cholecystectomy (open and laparoscopic) -- Chapter 33. Choledocholithiasis and cholangitis -- Chapter 34. Choledochal cyst and biliary strictures -- Chapter 35. Cancer of the gallbladder and bile ducts -- Section IX. Pancreas -- Chapter 36. Management of acute pancreatitis -- Chapter 37. Complications of acute pancreatitis (including pseudocysts) -- Chapter 38. Chronic pancreatitis -- Chapter 39. Disorders of the duodenal ampullae -- Chapter 40. Cystic neoplasms of the pancreas -- Chapter 41. Cancer of the pancreas and other periampullary cancers -- Chapter 42. Endocrine tumors of the pancreas -- Section X. Spleen -- Chapter 43. The spleen -- Section XI. Minimally invasive surgery -- Chapter 44. Fundamentals -- Chapter 45. Biliary tract -- Chapter 46. Hernia repair -- Chapter 47. Small bowel / colon Re -- Section XI. Minimally Invasive Surgery -- Chapter 48. Hiatal hernia repair and heller myotomy -- Chapter 49. Laparoscopic splenectomy -- Chapter 50. Video-assisted thoracic surgery of the esophagus -- Chapter 51. Laparoscopic andrealectomy -- Chapter 52. Laparoscopic surgery for morbid obesity -- Chapter 53. Laparoscopic staging and bypass.
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  • A study of the Speziale al Giglio apothecary shop in fifteenth-century Florence, Italy.
  • "This second edition provides guidance on all aspects of how to make and use antibodies for research, and commercial and industrial applications. All chapters are revised, updated, or expanded. New material in the book includes western blotting, aptamers, antibodies as therapeutics, quantitative production, and humanization of antibodies. The authors present descriptions of basic methods for making and using antibodies and describe basic laboratory techniques in detail. Each chapter includes introductory material, allowing for a better understanding of each concept. Practical examples are also included"--Provided by publisher.
  • Making Computerized Provider Order Entry Work is neither a scientific reference guide into medical informatics nor a book on theory or a summary of research studies in the field, but rather it is a practical guide to visioning and executing successful automation of physician workflow in the hospital environment. This adaptation of workflow is the work of a team, with leadership, clear vision, dedication, commitment, external drivers, experience, and the tireless work of those before us in this industry, who have paved the way with both successes and failure.Throughout the book, the author shares hard lessons-learned and guides the reader through the early warning signs that will help avoid the pitfalls. As systems progress, and the regulatory environments change, there will be new challenges and opportunities that will confront those setting up automated physician workflows. However, this book highlights and discusses all of the principles involved such as vision, leadership, project management and change management, which will always need to be incorporated to ensure project success. As such this book will be an important reference for anyone involved in the setting up or use of such systems from the physicians and medical professionals themselves through the medical informaticist to health system executives and other decision makers.
  • While spirituality has been generally recognized as an essential dimension of palliative care, uniformity of spiritual care practice has been lacking across healthcare settings due to factors like varying understandings and definitions of spirituality, lack of resources and practical tools, and limited professional education and training in spiritual care. In order to address these shortcomings, more than forty spiritual and palliative care experts gathered for a national conference to discuss guidelines for incorporating spirituality into palliative care. Their consensus findings form the basis of Making Health Care Whole. This important new resource provides much-needed definitions and charts a common language for addressing spiritual care across the disciplines of medicine, nursing, social work, chaplaincy, psychology, and other groups. This book also advocates a team approach to spiritual care, and specifies the roles of each professional on the team. Serving as both a scholarly review of the field as well as a practical resource with specific recommendations to improve spiritual care in clinical practice, Making Health Care Whole will benefit hospices and palliative care programs in hospitals, home care services, and long-term care services.
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    Chapter I. Microcirculation and reconstructive surgery -- Chapter II. Anomaly and cranio-facial surgery -- Chapter III. Wound healing and surgical oncology.
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  • 1 Seeing: blazing processing characteristics -- 2 Category representation and recognition evolvement -- 3 Neuroscientific inspiration -- 4 Neuromorphic tools -- 5 Insight from line drawings studies -- 6 Retina circuits signaling and propagating contours -- 7 The symmetric-axis transform -- 8 Motion detection -- 9 Neuromorphic architectures: pieces and proposals -- 10 Shape recognition with contour propagation fields -- 11 Scene recognition -- 12 Summary -- Terminology -- References -- Index.
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    A pivotal three decades : American psychiatry after World War II -- Emil Kraepelin : birth of modern descriptive psychiatry -- Kraepelin's progeny : the neo-Kraepelinians -- Robert L. Spitzer, psychiatric revolutionary -- The DSM-III Task Force and psychiatric empiricism -- A brief history of modern classification and problems with reliability in diagnosis -- The revolution begins, 1973-1976 -- A snapshot in time : DSM-III in midstream, 1976 -- The eruption of discord following the midstream conference -- Clinicians vs. researchers again and new antagonisms over sexuality -- The psychoanalytic awakening to DSM-III -- The field trials and yet more controversies -- The final weeks.
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    Using the findings of recent neuroscience, a psychologist reveals what sets humans apart from all other species, offering a fascinating exploration of our marvelous and sometimes frightening cognitive abilities and potentials. According to human genome research, there is a remarkable degree of overlap in the DNA of humans and chimpanzees. So what accounts for the rapid development of human culture throughout history and the extraordinary creative and destructive aspects of human behavior that make us so different from our primate cousins? Here the author explores in detail five distinctive parts of human cognition. These are the executive functions of working memory; a social intelligence with "mind-reading" abilities; a capacity for symbolic thought and language; an inner voice that interprets conscious experiences by making causal inferences; and a means for mental time travel to past events and imagined futures. He argues that it is the interaction of these five components that results in our uniquely human mind. This is especially true for three quintessentially human endeavors: morality, spirituality, and literacy, which can be understood only in light of the whole ensemble's interactive effects. He recaps the story of the human mind and speculates on its future. How might the Internet, 24/7 television, and smart phones affect the way the mind functions? Will the risk of mass distraction in our technology-saturated world inhibit further evolution of themind or will the superconnectivity of our expanding social networks enable us to share knowledge and collaborate in unprecedented ways, opening the human potential to breathtaking new heights? -- From back cover.
  • Spiritual heritage of health care -- Spirituality explored -- Spirituality within the context of holism -- Providing spiritual care : using a systematic approach -- Barriers influencing the provision of spiritual care -- Skills required to provide spiritual care -- Developments in spirituality : research and education -- Appendix: spirituality and spiritual care rating scale.
  • The first question -- Physics facts that will improve your images -- Screening mammography 101 and beyond -- The recalled patient : now what? findings on mammography -- Breast anatomy and physiology : knowing what's normal -- Calcifications made easy -- Management of masses : BI-RADS 2, 3, or 4? -- Multiple circumscribed masses -- Architectural distortion -- Mammographic asymmetries -- Expanding the differential diagnosis : going beyond IDC-NOS screening detection -- Finding cancers in dense tissue -- Measuring and managing breast cancer risk diagnostic exams/management -- The painful and the palpable -- Evaluation of nipple discharge -- The male breast -- Imaging the patient with breast cancer postoperative studies -- The postoperative breast -- Evaluating women with implants interventions -- Breast needle biopsy : tips for challenging cases.
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    Contents -- 1. Affections du tube digestif, avec la collaboration de G. Lauret et P. Olivier-Pallud -- 2. Affections du foie, du pancréas, maladies de la nutrition, parois abdominales, péritoine, avec la collaboration de G. Lauret, Jean Olivier et P. Olivier-Pallud -- 3. Affections de la peau, avec la collaboration de F. Hanoun et G. Vail -- 4. Afections des muqueuses génitales -- 5. Coeur, par H. Vignes et J. Dugas -- 6. Maladies des vaisseaux, avec la collaboration de J. Dugas -- [7.] Eclampsie et eclampsime.
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  • pt. 1. Malaria parasites and disease -- Structure and life cycle / H. Fujioka -- Malaria parasites and the Anopheles mosquito /G. Dimopoulos -- Malaria: pathogenicity and disease / M. English -- pt. 2. Malaria antigens -- Sporozoite antigens: biology and immunology of the circumsporozoite protein and thrombospondin-related anonymous protein / P. Sinnis -- Immune responses to liver-stage parasites: implications for vaccine development / M.R. Hollingdale -- Merozoite antigens involved in invasion / K. Berzins -- Asexual blood stages of malaria antigens: cytoadherence / D.I. Baruch -- Rosetting and autoagglutination in Plasmodium falciparum / V. Fernandez -- Sexual and sporogonic stage antigens / R.W. Sauerwein -- pt. 3. Malaria infection: immunity and regulation -- Mouse models of blood-stage malaria infections: immune responses and cytokines involved in protection and pathology / J. Langhorne -- Malaria and the immune system in humans / P. Perlmann -- Genetic regulation of malaria infection in humans / M. Troye-Blomberg -- pt. 4. Malaria vaccines -- Pre-erythrocytic malaria vaccines to prevent Plasmodium flaciparum malaria / W.R. Ballou -- Vaccines against asexual stage malaria parasites / S. Kumar -- Transmission-blocking vaccines / D.C. Kaslow -- Nucleic acid vaccines against malaria / D.L. Doolan -- Antidisease vaccines / L. Schofield -- Adjuvants and malaria vaccine development / L. Xiao -- Malaria vaccine trials / B. Greenwood.
  • Malaria methods and protocols 2002
    Springer Protocols
  • Malaria vaccine development : over 40 years of trials and tribulations / Giampietro Corradin & Howard Engers -- Malaria vaccines : reflections on 40 years of basic research and translation applications / Giampietro Corradin -- Challenges for the stakeholders / Howard Engers -- Plasmodium vivax vaccine surrogate markers of protection : dawning of a new era / Mary R. Galinski, Rabindra M. Tirouvanziam & Alberto Moreno -- Plasmodium vivax vaccine development in Colombia : advances and challenges / Myriam Arevalo-Herrera & Sócrates Herrera-Valencia -- Progress towards development of a vaccine for Plasmodium vivax malaria / Ahmad Rushdi Shakri & Chetan E. Chitnis -- Correlates of protection for Plasmodium falciparum malaria vaccine development : current knowledge and future research / James G. Beeson, Freya J.I. Fowkes, Linda Reiling, Faith H. Osier, Damien R. Drew & Graham V. Brown -- Plasmodium falciparum RTS,S vaccines and future development / Tom Egwang -- Plasmodium falciparum pre-erythrocytic vaccines : previous experience and the challenge of selecting new candidates / Thomas L. Richie & Joanne M. Lumsden -- Plasmodium falciparum whole-parasite malaria vaccines / Else M. Bijker & Robert W. Sauerwein -- Index.
  • Introduction: Malassezia Yeasts from a Historical Perspective / Roderick J. Hay and Gillian Midgley -- Biodiversity, Phylogeny and Ultrastructure / Eveline Guého-Kellermann, Teun Boekhout and Dominik Begerow -- Epidemiology of Malassezia-Related Skin Diseases / Takashi Sugita, Teun Boekhout, Aristea Velegraki, Jacques Guillot and Suzana Hađina, et al. -- Physiology and Biochemistry / Peter Mayser and George Gaitanis -- Malassezia Species and Immunity: Host - Pathogen Interactions / H. Ruth Ashbee and Ross Bond -- Pityriasis Versicolor and Other Malassezia Skin Diseases / Vicente Crespo Erchiga and Roderick J. Hay -- Malassezia Yeasts in Seborrheic and Atopic Eczemas / George Gaitanis, Peter Mayser, Annika Scheynius and Reto Crameri -- Malassezia Fungemia, Antifungal Susceptibility Testing and Epidemiology of Nosocomial Infections / Athanasios Tragiannidis, Andreas Groll, Aristea Velegraki and Teun Boekhout -- Genomics and Pathophysiology: Dandruff as a Paradigm / Jun Xu, Teun Boekhout, Yvonne DeAngelis, Tom Dawson and Charles W. Saunders -- Malassezia Yeasts in Animal Disease / Ross Bond, Jacques Guillot and F. Javier Cabañes -- Malassezia Database / Vincent A. Robert and Aristea Velegraki.
  • "An in depth examination of maldynia, also known as chronic pain, this book explores pain as a bio-cultural phenomenon that necessitates reexamination of medical philosophy, ethics, education, and practice. It provides a historical account of pain and then frames it with contemporary neurobiological perspectives. This book supplies a foundation upon which to illustrate (1) how what we know about pain could and should influence medical education, and the scope, and value (s) of medical practice, and (2) how a knowledge of the history and present considerations of pain might help to construct meaningful, patient-centered medicine"--Provided by publisher.
  • This monograph provides specialists and primary care physicians who are interested in hair with the practical know-how needed to achieve successful management of male alopecia. Guidance is first provided on the examination of hair loss in men, covering such aspects as clinical examination, the role of trichoscopy and the trichogram, laboratory work-up, and scalp biopsy. Diagnosis and treatment are then described in depth for a diverse range of conditions involving alopecia. Expert opinion is combined with the results of evidence-based medicine to provide the best current advice, highlighting the synergistic action of combination regimens and adjuvant treatments and explaining the concept of multitargeted treatment. All aspects of follow-up are covered, including compliance issues and expectation management. The role of hair care and cosmetics is also considered, with identification of potential adverse effects as well as benefits.
  • Part 1. Fundamentals -- Embryology and Functional Anatomy of the Male External Genitalia -- Diagnosis -- Fundamentals in Dermatopathology -- Part 2. Non-Infectious Inflammatory Disorders of the Male Genitalia -- Eczematous Dermatoses -- Papulosquamous Dermatoses -- Ulcerative Dermatoses -- Vesicobullous Dermatoses -- Granulomatous Dermatoses -- Part 3. Infectious Disorders of the Male Genitalia -- Nonsexually Transmitted Infections -- Sexually Transmitted Infections -- Part 4. Benign Specialized Disorders of the Male Genitalia -- Pigmentary Lesions/Pigmentary Skin Changes -- Cystic, Nodular, and Papular Lesions -- Vascular Lesions -- Miscellaneous Benign Disorders -- Part 5. Systemic Diseases and the Male External Genitalia -- Systemic Disorders Affecting the Genital Skin -- Part 6. Premalignant and Malignant Disorders of the Male Genitalia -- Premalignant Lesions of the Penis -- Squamous Cell Carcinoma and Secondary Tumors of the Penis and Scrotum -- Nonsquamous Malignant Neoplasms of the Penis and Scrotum.
  • Scientists investigating germ cells have, over the past 15 years, originated discoveries and innovations that give us valuable insights into the mechanisms that regulate not just stem cell function, but human development in its widest sense. With contributions from some of the leading researchers in the field, Male Germline Stem Cells: Developmental and Regenerative Potential assesses the implications of these discoveries for understanding the fundamental biology of germline stem cells as well as their potential for human stem cell-based therapies. This monograph covers many of the fundamental issues now being explored by today's generation of stem cell researchers, including the field's potential for regenerative medicine.
  • Initial consultation for male infertility -- Interpretation of basic semen analysis and advanced semen testing -- Azoospermia: diagnosis and management -- Ejaculatory dysfunction -- Genetic issues with male infertility -- Endocrinopathies in male infertility -- Female infertility: implications to management of male factor -- Variocele: to fix or not to fix -- Medical management of male infertility -- Surgical reconstructions for obstruction -- Techniques for sperm harvest -- Sperm banking: when, why, and how? -- Assisted reproduction and male factor fertility: which type is right? -- Ethical dilemmas in male infertility.
  • Part 1. Male Infertility Diagnosis and Management -- Causes of Male Infertility / Herbert J. Wiser, Jay Sandlow and Tobias S. Köhler -- Laboratory Evaluation for Male Infertility / Ryan Mori and Edmund Sabanegh Jr. -- Imaging Modalities in the Management of Male Infertility / Marcello Cocuzza and Sijo J. Parekattil -- Endocrinopathies / Sam Haywood, Eric L. Laborde and Robert E. Brannigan -- Molecular Mechanisms of Antioxidants in Male Infertility / Kathleen Hwang and Dolores J. Lamb -- Surgical Treatment for Male Infertility / Sandro C. Esteves and Ricardo Miyaoka -- Microsurgery for Male Infertility: The AIIMS Experience / Rajeev Kumar -- Advanced Techniques of Vasoepididymostomy / Wayland Hsiao and Marc Goldstein -- Grafting Techniques for Vasectomy Reversal / Henry M. Rosevear and Moshe Wald -- Mini-Incision Vasectomy Reversal Using the No-Scalpel Vasectomy Instruments and Principles / Darby J. Cassidy, Keith Jarvi, Ethan D. Grober and Kirk C. Lo -- Robotic Microsurgery for Male Infertility and Chronic Orchialgia / Jamin V. Brahmbhatt and Sijo J. Parekattil -- Robot-Assisted Vasectomy Reversal / Peter Frank De Wil, Vincenzo Ficarra, George A. de Boccard and Alexandre Mottrie -- Robotic-Assisted Varicocelectomy / Tung Shu and Run Wang -- Epidemiological Considerations in Male Infertility / Mark A. Faasse and Craig S. Niederberger -- Male Infertility from the Developing Nation Perspective / Kasonde Bowa and John S. Kachimba -- Ethical Dimensions of Urology: Four Case Studies / Marc S. Cohen and Ray E. Moseley -- Management of Fertility in Male Cancer Patients / Daniel H. Williams IV -- Genetic Aspects of Male Infertility / Orhan Bukulmez -- Novel Approaches in the Management of Klinefelter Syndrome / Fnu Deepinder -- ART and Its Impact on Male Infertility Management / Alice Rhoton-Vlasak and Kenneth C. Drury -- Part 2. Spermatozoa Metabolism -- Fuel/Energy Sources of Spermatozoa / M. M. Misro and T. Ramya -- Oxidative Stress / Fanuel Lampiao, C. J. Opperman, Ashok Agarwal and Stefan S. du Plessis -- Loss of Intracellular Antioxidant Enzyme Activity During Sperm Cryopreservation: Effects on Sperm Function After Thawing / Juan G. Alvarez -- Part 3. Common Male Infertility Disorders -- Varicocele / Sandro C. Esteves -- Infection in Infertility / Ralf Henkel -- Ejaculatory Dysfunction and Vasodynamics / Aleksey P. Ignatov and Paul J. Turek -- Environmental Factors / Claudio Telöken, Samuel Juncal and Túlio M. Graziottin -- Exogenous Medication or Substance-Induced Factors / Kubilay Inci and Levent Mert Gunay -- Sperm DNA Damage and Antioxidant Use: Roles in Male Fertility / Ashok Agarwal and Aspinder Singh -- Common Male Infertility Disorders: Aging / Fabio Pasqualotto, Edson Borges Jr. and Eleonora Pasqualotto -- Apoptosis and Male Infertility / S. Vaithinathan, Shereen Cynthia D'Cruz and P. P. Mathur -- Impact of Spinal Cord Injury / Viacheslav Iremashvili, Nancy L. Brackett and Charles M. Lynne -- Obesity and Male Fertility / Stephanie Cabler, Ashok Agarwal and Stefan S. du Plessis -- Part 4. Nutrition and Antioxidants Role for Male Reproductive Health -- Nutritional Pathways to Protect Male Reproductive Health / Tung-Chin Hsieh and Paul Shin -- Natural Antioxidants / Giancarlo Balercia, Antonio Mancini and Gian Paolo Littarru -- Synthetic Antioxidants / Edmund Y. Ko, John C. Kefer, Ashok Agarwal and Edmund Sabanegh -- Antioxidant Therapy for the Enhancement of Male Reproductive Health: A Critical Review of the Literature / Kelton Tremellen -- In Vitro Studies of Antioxidants for Male Reproductive Health / Armand Zini and Maria San Gabriel -- Part 5. Assisted Reproductive Technologies in Male Fertility -- Micro-testicular Sperm Extraction / Doron Sol Stember and Peter Schlegel -- Sperm Processing and Selection / Sonja Grunewald and Uwe Paasch -- Antioxidants in Sperm Cryopreservation / Tamer Said and Ashok Agarwal -- Antioxidants in ICSI / Nicolas Garrido, Sandra García-Herrero, Laura Romany, José Remohí and Antonio Pellicer, et al. -- Antioxidants in IMSI / Monica Antinori -- Role of Sperm-Hyaluronic Acid Binding in the Evaluation and Treatment of Subfertile Men with ROS-Affected Semen: Assessment of Sperm with Oxidative Damage and HA-Mediated ICSI Sperm Selection / Ciler Celik-Ozenci and Gabor Huszar -- Extended Embryo Culture Supplementation / Alex C. Varghese, Eulalia Pozo-Guisado, Ignacio S. Alvarez and Francisco Javier Martin-Romero -- Part 6. Special Topics -- Best Practice Guidelines for the Use of Antioxidants / Francesco Lanzafame, Sandro La Vignera and Aldo E. Calogero -- Harmful Effects of Antioxidant Therapy / Adam F. Stewart and Edward D. Kim.
  • Male LUTS/BPH Made Easy is an up-to-date comprehensive reference on the management of Lower Urinary Tract Symptoms (LUTS) due to Benign Prostatic Enlargement (BPE), which incorporates all of the key issues in the field of management of male lower urinary tract symptoms and benign prostatic disease. Male LUTS/BPH Made Easy aims to update the reader on the most current treatments and assist in clinical decision making based on the latest evidence.
  • Normal anatomy and physiology / Paul Milhoua, Daniel Lowe, and Arnold Melman -- Epidemiology of erectile dysfunction / Ridwan Shabsigh -- Cardiac issues related to erectile dysfunction / Thorsten Reffelmann and Robert A. Kloner -- How a primary care clinician approaches erectile dysfunction / Richard Sadovsky and Kevin Custis -- Psychological aspects related to erectile dysfunction / Michael A. Perelman -- Hormonal evaluation and treatment / Jeremy P.W. Heaton and Alvaro Morales -- Radical prostatectomy and other pelvic surgeries: effects on erectile function / Muammer Kendirici, Jeffrey Bejma, Wayne J.G. Hellstrom -- Drugs that affect male sexual function / Benjamin K. Yang and Craig F. Donnatucci -- Neurogenic sexual dysfunction in men and women / Kazem M. Azadozoi and Mike B. Siroky -- Female sexual dysfunction / Irwin Goldstein -- Evaluation of the patient with erectile dysfunction / Jeffrey C. LaRochelle and Laurence A. Levine -- Oral therapy for erectile dysfunction / Raymond W. Pak and Gregory A. Broderick -- Intracavernosal injection with vasoactive agents / Alice K. Tsao and Ajay Nehra -- Topical and intra-urethral therapy / John C. Hairston, Edguardo Becher, and Kevin T. McVary -- Vacuum erection devices / Hunter Wessells -- Penile implants / Steven K. Wilson and John J. Mulcahy -- Peyronie's disease: history and medical therapy / J. Slade Hubbard and Culley C. Carson -- Peyronie's disease: surgical therapy / Gerald H. Jordan -- Vascular surgery for erectile dysfunction / William O. Brant ... [et al.] -- Priapism / Lawrence S. Hakim -- Ejaculatory disorders / Chris G. McMahon -- Gene therapy for erectile dysfunction / Thomas R. Magee, Jacob Rajfer, and Nestor F. Gonzalez-Cavidad.
  • Morphological and Functional Characteristics of Serous Cavities / Olga V. Lebedinskaya, Irina Zh Shubina, Natalia Yu Anisimova, Alexey N. Kopylov and Mikhail V. Kiselevsky -- Pathogenesis of Malignant Effusions / Irina O. Chikileva, Natalia Yu Anisimova, Irina Zh Shubina and Mikhail V. Kiselevsky -- Diagnosis and Treatment of Malignant Pleural Effusion / Sergi Call, David Sánchez and Ramón Rami-Porta -- Malignant Ascites: Diagnosis and Treatment / Fausto Petrelli and Sandro Barni -- Malignant Pericardial Disease / Caroline Chiles and Girish Shroff -- Adoptive Immunotherapy of Malignant Effusions / Irina Zh Shubina, Konstantin S. Titov, Irina O. Chikileva, Lev V. Demidov and Mikhail V. Kiselevsky -- Hyperthermia and Intracavitary Chemotherapy in Prevention and Treatment of Malignant Effusions / Gianfranco Baronzio, Giammaria Fiorentini, Marco Ballerini, Valter Cassuti and Giorgio Forzenigo, et al.
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    "Cancer can kill: this fact makes it concrete. Still, it's a devious knave. Nearly every American will experience it up-close and all too personally, wondering why the billions of research dollars thrown at the word haven't exterminated it from the English language. Like a sapper diffusing a bomb, Jain unscrambles the emotional, bureaucratic, medical, and scientific tropes that create the thing we call cancer. Scientists debate even the most basic facts about the disease, while endlessly generated, disputed, population data produce the appearance of knowledge. Jain takes the vacuum at the center of cancer seriously and demonstrates the need to understand cancer as a set of relationships--economic, sentimental, medical, personal, ethical, institutional, statistical. Malignant analyzes the peculiar authority of the socio-sexual psychopathologies of body parts; the uneven effects of expertise and power; the potentially cancerous consequences of medical procedures such as IVF; the huge industrial investments that manifest themselves as bone-cold testing rooms; the legal mess of medical malpractice law; and the teeth-grittingly jovial efforts to smear makeup and wigs over the whole messy problem of bodies spiraling into pain and decay. Malignant examines the painful cognitive dissonances produced by the ways a culture that has relished dazzling success in every conceivable arena have twisted one of its staunchest failures into an economic triumph. The intractable foil to American achievement, cancer hands us -- on a silver platter and ready for Jain's incisively original dissection -- our sacrifice to the American Dream"-- Provided by publisher.
  • Mineralogy of Asbestos -- Epidemiology of Mesothelioma and Historical Background -- Imaging of Mesothelioma -- Biopsy Techniques for the Diagnosis of Mesothelioma -- Pathohistological Diagnosis and Differential Diagnosis -- Mesothelioma and Analysis of Tissue Fiber Content -- Surgical Therapy of Mesothelioma -- Chemotherapy and Radiotherapy for Mesothelioma -- Genetics and Molecular Biology of Mesothelioma -- Early Stages of Mesothelioma, Screening and Biomarkers.
  • This book is a comprehensive analysis of the definitions, concepts, and recent research on malingering, feigning, and other response biases in psychological injury/ forensic disability populations. It presents a new model of malingering and related biases, and develops a "diagnostic" system based on it that is applicable to PTSD, chronic pain, and TBI. Included are suggestions for effective practice and future research based on the literature reviews and the new systems, which are useful also because they can be used readily by psychiatrists as much as psychologists.
  • Principles of medical malpractice -- Errors, incidents and complications in general surgery -- Retained surgical foreign bodies -- Quality management related to wrong-site surgery -- Towards a preventive safety culture within the hospital -- Ethical aspects of an open safety culture : towards a new physician-patient relationship in 21st century medicine.
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    1. Animals in Mamluk society -- 2. The Pre-Mamluk veterinary traditions -- 3. Scholars, equestrians, and veterinarians -- 4. The Veterinary profession -- 5. Theoretical aspects -- 6. Preventive medicine and diagnostics -- 7. Non-invasive practises in veterinary treatment -- 8. Invasive methods of treatment in veterinary medicine.
  • Sexual Differentiation of the Brain: Genetic, Hormonal and Trophic Factors / Hugo F. Carrer and María J. Cambiasso -- Life at the Interface Between a Dynamic Environment and a Fixed Genome: Epigenetic Programming of Stress Responses by Maternal Behavior / Ian C. G. Weaver -- Effects of Early Life Seizures and Anti-epileptic Drug Treatment on Human Brain Development in Human Models / Eric D. Marsh and Amy R. Brooks-Kayal -- Prenatal Development of the Human Blood-Brain Barrier / Luca Cucullo -- Seizure Propensity and Brain Development: A Lesson from Animal Models / Jana Velíšková, Annamaria Vezzani and Astrid Nehlig -- Seizures and Antiepileptic Drugs: Does Exposure Alter Normal Brain Development in Animal Models? / Aristea S. Galanopoulou, Libor Velíšek and Solomon L. Moshé -- Overview of Neural Mechanisms in Developmental Disorders / Ayush Batra, Erin Carlton and Kathleen Franco -- Drug Permeation Across the Fetal Maternal Barrier / Chaitali Ghosh and Nicola Marchi -- In Vivo Imaging of Brain Development: Technologies, Models, Applications, and Impact on Understanding the Etiology of Mental Retardation / Vicko Gluncic -- Congenital, Non-inheritable Chromosomal Abnormalities Responsible for Neurological Disorders / Riccardo Bianchi and Patrizia D'Adamo.
  • Earliest evidence of Deltatheroida (Mammalia: Metatheria) from the early Cretaceous of North America / Brian M. Davis, Richard L. Cifelli and Zofia Kielan-Jaworowska -- Evolution of hind limb proportions in kangaroos (Marsupialia: Macropodoidea) / Benjamin P. Kear ... [et al.] -- Changing views in paleontology : the story of a giant (Megatherium, Xenarthra) / Christine Argot -- Evolutionary morphology of the Tenrecoidea (Mammalia) forelimb skeleton / Justine A. Salton and Eric J. Sargis -- Postcranial morphology of Apheliscus and Haplomylus (Condylarthra, Apheliscidae) : evidence for a Paleocene Holarctic origin of Macroscelidea / Tonya A. Penkrot ... [et al.] -- Postcranial skeleton of the Upper Paleocene (Itaboraian) "Condylarthra" (Mammalia) of the Itaboraí Basin, Brazil / Lilian P. Berqvist -- Postcranial osteology of mammals from Salla, Bolivia (late Oligocene) : form, function, and phylogenetic implications / Bruce J. Shockey and Frederico Anaya -- Evolution of the proximal third phalanx in Oligocene-Miocene equids, and the utility of phalangeal indices in phylogeny reconstruction / Jay A. O'Sullivan -- Adaptive zones and the pinniped ankle : a three-dimensional quantitative analysis of carnivoran tarsal evolution / P. David Polly -- The biogeographic origins of Primates and Euprimates : east, west, north, or south of Eden? / Mary T. Silcox -- Evaluating the mitten-gliding hypothesis for Paromomyidae and Micromomyidae (Mammalia, "Plesiadapiformes") using comparative functional morphology of new Paleogene skeletons / Douglas M. Boyer and Jonathan I. Bloch -- Morphological diversity in the skulls of large adapines (Primates, Adapiformes) and its systematic implications / Marc Godinot and Sébastien Couette -- Primate tibiae from the middle Eocene Shanghuang fissure-fillings of eastern China / Marian Dagosto ... [et al.] -- Rooneyia, postorbital closure, and the beginnings of the age of Anthropoidea / Alfred L. Rosenberger, Russell Hogg and Sai Man Wong -- Epitensoric position of the chorda tympani in Anthropoidea : a new synapomorphic character, with remarks on the fissura Glaseri in Primates / Wolfgang Maier -- Evolutionary morphology of the guenon postcranium and its taxonomic implications / Eric J. Sargis, Carl J. Terranova and Daniel L. Gebo -- Analysis of selected hominoid joint surfaces using laser scanning and geometric morphometrics : a preliminary report / William E.H. Harcourt-Smith ... [et al.] -- Comparative primate bone microstructure: records of life history, function, and phylogeny / Johanna Warshaw.
  • Cellular heterogeneity of the neonatal SVZ and its contributions to forebrain neurogenesis and gliogenesis / Steven W. Levison and James E. Goldman -- Extrinsic and intrinsic factors modulating proliferation and self-renewal of multipotential CNS progenitors and adult neural stem cells of the subventricular zone / Sara Gil-Perotin and Patrizia Casaccia-Bonnefil -- Birth, migration and function of SVZ derived neurons in the adult brain / Minoree Kohwi, Rui Pedro Galvão and Arturo Alvarez-Buylla -- Contributions of the neocortical SVZ to human brain development / Nada Zecevic ... [et al.] -- Responses of the adult SVZ to neuronal death and injury / Jason G. Emsley and Jeff D. Macklis -- Resonses of the SVZ to radiation and chemotherapy / Ami M. Karkar, Radoslaw Rola and John R. Fike -- The subventricular zone responds dynamically to mechanical brain injuries / Maria L.V. Dizon and Francis G. Szele -- Responses of the SVZ to hypoxia and hypoxia/ischemia / Ryan J. Felling ... [et al.] -- Responses of the SVZ to demyelinating diseases / B. Nait-Oumesmar ... [et al.] -- Auxiliary proliferative zones in the developing and adult central nervous system: lessons from studies on the effects of ethanol / Michael W. Miller and Marla B. Bruns.
  • v. 2 Springer
  • Adenoma -- Adenoma, tubular -- Adenomyoepithelioma -- Adenosis -- Angiosarcoma -- Arteriosclerosis -- Artifact, cream -- Atheroma -- Burn trauma -- Carcinoma -- Carcinosarcoma -- Cysts -- DCIS -- Fat necrosis -- Fibroadenoma -- Galactography -- Gel bleeding -- Gout -- Gynecomastia -- Hamartoma -- Hematoma -- Insect bite -- Lipoma -- Local relapse -- Lymphadenitis -- Mastitis, focal -- Mastitis, postoperative -- Mastopathy, fibrocystic -- Mucinous carcinoma -- Paget disease -- Papilloma, intraductal -- Papillomatosis, intraductal -- Prosthesis rupture -- Radial scars.
  • "This book contains a series of chapters on various aspects of management and leadership in a health care organisation, written by some of the most experienced authors from around the world. It provides an understanding of basic management and leadership skills that are essential for clinical as well as non-clinical staff in a health care organisation, in a simple and clear fashion. The topics covered in this book range from preparing for an interview, the art of negotiation and handling difficult behaviour, to clinical leadership, evidence based management, mentorship, and conflict resolution. With its simple and reader friendly approach this unique and concise book will be useful for all staff working in a health care organisation irrespective of their faculty, position, and stage in career in becoming successful consultants, managers, supervisors, and leaders."--From the publisher.
  • Hernia repair is one of the commonest operations in general surgery. Open or laparoscopic repair of a primary inguinal hernia is a relatively straightforward operation, but more complex abdominal wall hernias demand greater surgical skill and knowledge. The editors have assembled the world's top herniologists to describe and illustrate numerous surgical techniques in detail. The field of herniology has developed rapidly over the last few years. Since the previous edition of this book, published in 2003, new surgical techniques have been developed and many new prosthetic and biologic materials have been introduced. Management of Abdominal Hernias 4e presents an authoritative, comprehensive and fully updated account of the surgical techniques and the available prosthetic materials for performing repair of abdominal wall hernias. Both open and laparoscopic methods are included. It is aimed at general and specialist surgeons in the practice of clinical surgery, as well as trainee surgeons.
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  • Epidemiology of acute obstetric emergencies -- Acute changes in fetal heart rate tracing: when it becomes an emergency -- Evaluation and management of antepartum and intrapartum hemorrhage -- Evaluation and management of postpartum hemorrhage -- Amniotic fluid embolism -- Pulmonary embolism in pregnancy -- Peripartum cardiomyopathy and pulmonary edema -- Management of severe sepsis and septic shock -- Management of hypertensive crisis including stroke -- Management of eclampsia -- Subcapsular liver hematoma -- Diabetic ketoacidosis -- Thyroid storm in pregnancy -- Cardiorespiratory arrest and cardiorespiratory resuscitation in pregnancy -- Indications and techniques for transcervical and abdominal cerclage -- Techniques and complications of planned and emergency cesarean section -- Avoiding and managing lower urinary tract injury during vaginal and abdominal deliveries.
  • Diagnostic approach to the patient with suspected pulmonary embolism. Clinical probablility and D-dimer testing / Philip S. Wells -- Imaging of acute pulmonary embolism / James G. Ravenel and U. Joseph Schoepf -- The search for deep vein thrombosis: evaluation of the leg veins / Jan Beyer and Sebastian M. Schellong -- Risk stratification of pulmonary embolism: detection and prognostic impact of right ventricular dysfunction / Stavros V. Knostantinides -- Cardiac biomarkers in the diagnostic workup of pulmonary embolism / Evangelos Giannitsis and Hugo A. Katus -- Importance of a patent foramen ovale / Annette Geibel, Manfred Zehender, and Wolfgang Kasper -- Contemporary diagnostic algorithm for the hemodynamically stable patient with suspected pulmonary embolism / Arnaud Perrier -- Contemporary diagnostic algorithm for the hemodynamically unstable patient with suspected pulmonary embolism / Stavros V. Konstantinides -- Treatment and secondary prophylaxis of venous thromboembolism. Heparin anticoagulation / Graham F. Pineo and Russell D. Hull -- Thrombolysis / Guy Meyer -- Management of the patient with fulminant pulmonary embolism undergoing cardiopulmonary resuscitation / Fabian Spöhr and Bernd W. Böttiger -- Surgical pulmonary embolectomy / Ani C. Anyanwu and Lishan Aklog -- Interventional approaches to the treatment of acute massive pulmonary embolism / Nils Kucher -- Vitamin K antagonists and novel oral anticoagulants / Giancarlo Agnelli and Cecilia Becattini -- Specific aspects. Hereditary and acquired thrombophilia / Hanno Riess -- Venous thromboembolism and cancer / Paolo Prandoni, Anna Falanga, and Andrea Piccioli -- Pulmonary embolism in pregnancy / Simon J. McRae and Shannon M. Bates -- Venous thromboembolism in the era of air travel / Frédéric Lapostolle ... [et al.] -- Chronic thromboembolic pulmonary hypertension / Irene M. Lang and Walter Klepetko.
  • Gastroesophageal cancers : providing an update / Jaffer A. Ajani -- Epidemiology and etiology of gastric cancer / Amitesh Roy, David Cunningham & Ian Chau -- Surgery of esophagogastric cancer : standards and challenges / Markus Moehler, Anne Palmqvist, Hauke Lang, Hans-Joachim Meyer & Ines Gockel -- Chemotherapy / Vincenzo Catalano & Francesco Graziano -- Targeted therapies / David H. Ilson & Elizabeth C. Smyth -- Guidelines for managing gastric cancer / Vikas Ghai & Yixing Jiang.
  • This book provides a single, comprehensive reference source that incorporates the epidemiology, natural history, and the latest genetic and molecular biological findings of bladder cancer. This book discusses the diagnostic and staging evaluation of both non-muscle invasive and invasive bladder cancer and incorporates the new findings on markers for the diagnosis of bladder cancer. Risk stratified treatment of non-muscle invasive bladder cancer including various approaches to intravesical therapy are reviewed. Current guideline-based approaches to management and new data regarding diagnosis and prognostication of muscle invasive bladder cancer is analyzed and summarized. This book covers the application of chemotherapy for muscle invasive and advanced disease. The evidence-based application of multimodality therapy is highlighted. Gaps in current knowledge and important areas for clinical research are highlighted. Authored by experts in their respective fields, Management of Bladder Cancer: A Comprehensive Text with Clinical Scenarios serves as an easy and complete reference source for clinicians, researchers, individuals in training, allied health professionals and medical students in the fields of Urology, Medical Oncology, Radiation Oncology, Basic and Translational Science and Epidemiology.
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    Epidemiology : incidence, causes, severity and outcome / Richard Appleton -- Resuscitation and acute treatment of brain injuries (traumatic and atraumatic) / Jane Ratcliffe -- Head (brain) injury rehabilitation team / Richard Appleton, Liz Furlong, and Tony Baldwin -- Immediate medical and nursing needs / Liz Furlong, Julie Sellars, Tamsyn Doyle and Richard Appleton -- Assessment and management of physical (motor and functional) difficulties / Nicola Henderson, Eileen Kinley, Sue Loughran with contributions from Susie Harrison, Paul Ritson, and Juliet Weston -- Assessment and management of feeding and swallowing difficulties / Helen Gore and Suzanne Wood -- Speech and language difficulties / Helen Gore and Suzanne Wood -- Cognitive problems / Tony Baldwin, Colin Demellweek, Peter Rankin and Fran Carleton -- Emotional, behavioural, psychiatric and social problems / Colin Demellweek, Peter Rankin, and Tony Baldwin -- The impact of brain injury on the family / Colin Demellweek and Richard Appleton -- Community liaison / Jackie Gregg and Tony Baldwin -- Prevention of brain injury / Jackie Gregg and Richard Appleton -- The future / Richard Appleton -- A parent's and her daughter's view / Paula and Lizzie Pearson.
  • 1. Background and Epidemiology -- Basic Science of Breast Cancer in Older Patients / Irmgard Irminger-Finger -- Tumor Biology and Pathology / Virginie Durbecq and Denis Larsimont Clinical Epidemiology and the Impact of Co-Morbidity on Survival / Adri C. Voogd, Marieke J. Louwman and Jan Willem W. Coebergh -- 2. Special Considerations in the Management of Older Women -- Comprehensive Geriatric Assessment / Margot A. Gosney -- A Practical Mini-Guide to Comprehensive Geriatric Assessment / Siri Rostoft Kristjansson -- Impact of the Physiological Effects of Aging on the Pharmacokinetics and Pharmacodynamics of Systemic Breast Cancer Treatment / Paul Hamberg, Maja J. A. de Jonge and Caroline M. Seynaeve -- Impact of Hormone Replacement Therapy on Breast Cancer / Toral Gathani and Valerie Beral -- Experiences of a Multidisciplinary Elderly Breast Cancer Clinic: Using the Right Specialists, in the Same Place, with Time / Anne Stotter, Mohammad Tahir, Robert S. Pretorius and Thompson Robinson -- 3. Therapeutics -- Mammographic Breast Screening in Elderly Women / Lynda Wyld -- Primary Endocrine Therapy for the Treatment of Early Breast Cancer in Older Women / Lynda Wyld and Daniel Hind -- Peroperative Radiotherapy / Roberto Orecchia, Giovanni Battista Ivaldi and Maria Cristina Leonardi -- General and Local Anesthetics / Bernadette Th. Veering -- The Surgical Management of Breast Cancer in Elderly Women / Malcolm W. R. Reed, Lynda Wyld and Riccardo A. Audisio -- Breast Reconstruction / Marcus J. D. Wagstaff, Malcolm W. R. Reed and Christopher M. Caddy -- Adjuvant Endocrine Therapy / Laura Biganzoli -- Adjuvant Chemotherapy / Sumanta Kumar Pal, Nilesh Vora and Arti Hurria -- Adjuvant Radiotherapy / Pierre G. M. Scalliet -- Prevention and Treatment of Skeletal Complications / Matthew C. Winter, Helen L. Neville-Webbe and Robert E. Coleman -- Medical Management of Advanced Disease / Hans P. M. W. Wildiers -- The Use of Chemotherapy in Elderly Cancer Patients: Dose Adjusting, Drug Interactions, and Polypharmacy / Lazzaro Repetto and Claudia Di Bartolomeo -- 4. Psychosocial Considerations -- Delayed Presentation of Breast Cancer in Older Women / Lindsay J. L. Forbes and Amanda J. Ramirez -- Patient Decision Making / Martine Extermann -- Culture, Ethnicity, and Race: Persistent Disparities in Older Women with Breast Cancer / Antonella Surbone and Marjorie Kagawa-Singer -- Supportive, Palliative and End-of-Life Care for Older Breast Cancer Patients / Elaine Cachia, Ruth Broadhurst and Sam H. Ahmedzai.
  • Anatomy and Physiology of the Breast -- Congenital and Developmental Abnormalities of the Breast -- Nipple Discharge -- Mastalgia -- Management of Common Lactation and Breastfeeding Problems -- Evaluation of a Breast Mass -- Breast Cancer Epidemiology -- Breast Cancer Screening -- Breast Imaging -- Premalignant and Malignant Breast Pathology -- Lobular Carcinoma in Situ -- Ductal Carcinoma in Situ -- Surgical Considerations in the Management of Primary Invasive Breast Cancer -- Sentinel Node Concept -- Breast Reconstructive Surgery -- The Role of Radiotherapy in Breast Cancer Management -- Adjuvant Systemic Therapy for Breast Cancer: An Overview -- Endocrine Therapy -- Chemotherapeutic Agents -- HER2-Targeted Therapy -- Inflammatory and Locally Advanced Breast Cancer -- Preoperative (Neoadjuvant) Systemic Therapy -- Metastatic Breast Cancer -- Hormone Replacement Therapy: A Critical Review -- Breast Diseases in Males -- Breast Cancer in the Elderly -- Breast Cancer in Younger Women -- Psychological Support for the Breast Cancer Patient -- Management of the Patient with a Genetic Predisposition for Breast Cancer -- Chemoprevention of Breast Cancer -- Design, Implementation, and Interpretation of Clinical Trials -- Structure of Breast Care Center -- Medicolegal Pitfalls in Breast Cancer Diagnosis and Management.
  • v. 2 Springer
    v. 3 Springer
    v. 4 Springer
  • 2012 ClinicalKey
    Section 1. Screening/prevention -- section 2. Diagnosis/assessment -- section 3. Treatment -- section 4. Supportive care -- section 5. Rehabilitation/survivorship -- section 6. Special issues.
  • "This book summarizes the great progress in the treatment of cardiovascular disease (CVD). Due to improved therapies, preventive strategies and increased public awareness, CVD mortality has been on the decline for both genders. Unfortunately, the decline has been less prominent for women, and CVD remains the leading cause of mortality for women in the United States and is responsible for a third of all deaths of women worldwide. Management of Cardiovascular Disease in Women provides a comprehensive overview of differences in cardiac problems in women including the challenges and limitations of the available literature. Unique aspects to women's heart health such as pregnancy, the impact of emotional stress and other psychosocial issues are discussed by leading experts in the field. They therefore provide important insight to cardiovascular care in women, making this book an essential resource for a wide range of practitioners including cardiologists, primary care providers, internists, and reproductive healthcare professionals."--Publisher's website.
  • This volume provides new data about the molecular biology of CRPC and a review of the definition, staging and prognostic factors that define CRPC. The book features an in-depth review of proven therapeutic options, including bone-targeted therapies, immunotherapy, chemotherapy and hormonal based therapies. Combination therapy as well as novel targeted approaches presently under investigation are also reviewed. The text provides up-to-date guidelines and algorithms for the management of CRPC based on international guidelines presently available as well as evidence-based medicine. As a concise yet comprehensive summary of the current status of the field, Management of Castration Resistant Prostate Cancer serves as a very useful resource for physicians and researchers dealing with this challenging malignancy.
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  • This book presents a comprehensive and instructive management plan for physicians who care for CKD patients. Basic aspects of CKD, clinical assessment, evaluation and management of risk factors, cardiovascular disease in the context of CKD, assessment and management of CKD complications, special circumstances in CKD patients, and the path to renal replacement therapy are all thoroughly covered. Diagnostic and therapeutic approaches are presented according to the latest staging system for CKD, with patient care being discussed separately for each disease stage. The proposed management plan is both 'best available evidence based' and 'practice based'. The book also recognizes the needs of busy clinicians by including helpful boxes summarizing the evidence on diagnostic and therapeutic issues and practice pearls based on guidelines. The authors are recognized experts from across the world, ensuring global coverage of the problem, and most have participated in writing guidelines on CKD.
  • The risk of cancer increases with age and the number of older adults seeking treatment is rising dramatically in line with the aging population. The care of older patients differs from that of younger adults because of variation in the biology of the tumor, age-related variation in host physiology, co-morbidity burden and psychosocial issues, which might impact the efficacy and side effects of cancer therapy. Management of Colorectal Cancers in Older People focuses on treatment strategies of colorectal cancers and provides guidance on the issues specific to older patients, spanning background and epidemiology, special considerations in the care of older people, therapeutics, and psychosocial considerations. This book offers a thorough review of current approaches to treating older colorectal cancer patients, detailing the special issues and considerations involved. The discipline-spanning coverage outlines best practice and proposes topics for future research. The third volume in the Management of Cancer in Older People series, this book will be of interest to all surgical oncologists, medical and radiation oncologists, gerontologists, proctologists and other members of the multidisciplinary team involved in the care of elderly colorectal cancer patients.
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  • Ch. 1 Refractive surgery outcomes and frequency of complications / Wallace Chamon and Norma Allemann -- Ch. 2 Influence of refractive surgery complications on quality of life / Konrad Pesudovs -- Ch. 3 LASIK: intraoperative (flap) complications / Stephen G. Slade -- Ch. 3.2 Incomplete LASIK flap / Helen K. Wu and Waleed A. Allam -- Ch. 3.3 Dislocated flaps: how to solve free flaps with no marks or flap malposition / Julio Baviera -- Ch. 3.4 Management of the distorted flap / David R. Hardten -- Ch. 4.1 Infections after refractive surgery / Jóse de la Cruz, Joelle Hallak, Dimitri Azar, and Sandeep Jain -- Ch. 4.2 Diffuse lamellar keratitis / Marlene J. Brown, David R. Hardten, Elizabeth A. Davis and Richard L. Lindstrom -- Ch. 4.3 Pressure-induced interlamellar stromal keratitis / Sadeer B. Hannush and Michael W. Belin -- Ch. 4.4 Prevention and management of flap striae after LASIK / Roger F. Steinert -- Ch. 4.5 Marginal sterile corneal infiltrates after LASIK / Renato Ambrósio Jr., Daniela Jardim, and Bruno M. Fontes -- Ch. 4.6 Ptosis / Bryan S. Sires -- Ch. 4.7 Melting / José L. Güell, Merce Morral, Oscar Gris, Javier Gaytan, and Felicidad Manero -- Ch. 5.1 Dry eye / Jerome C. Ramos-Estevan and Steven Wilson -- Ch. 5.2 Epithelial ingrowth / Gustavo E Tamayo -- Ch. 5.3 Corneal ectasia / J. Bradley Randleman and R. Doyle Stulting -- Ch. 5.4 Scarring / Eric E. Gabison and Thanh Hoang-Xuan -- Ch. 6 Refractive miscalculation with refractive surprise -- Ch. 6.1 Sphere / Arturo S. Chayet and Luis F. Torres -- Ch. 6.2 Cylinder / Noel Alpins and Gemma Walsh -- Ch. 7.1 Optical implications of corneal photorefractive surgery / Vikentia J. Katsanevaki -- Ch. 7.2 Night vision disturbances after refractive surgery / César Albarrán, David Piñero, and Jorge L. Alió -- Ch. 7.3 Decentration / Jonathan H. Talamo -- Ch. 7.4 Corneal irregularity / Jorge L. Alió -- Ch. 8 Optic neuropathy and retinal complications after refractive surgery / J. Fernando Arevalo, Reinaldo A. Garcia, Rafael A. Garcia-Amaris, and Juan G. Sanchez -- Ch. 9.1 Complications and management with the femtosecond laser / Karl G. Stonecipher, Teresa S. Ignacio, and Kody G. Stonecipher -- 9.2 Management of a perforated femtosecond laser-created flap / Vance Thompson -- Ch. 10 Corneal haze after refractive surgery / David Fahd, José de la Cruz, Sandeep Jain and Dimitri Azar -- Ch. 11 Complications of LASEK / David P.S. O'Brart -- Ch. 12 Complications of refractive keratotomy / Carlo F. Lovisolo, Alessandro Mularoni, Antonio Calossi, Charles Wm. Stewart -- Ch. 13 Anterior chamber angle-supported complications: prevention and treatment / Orkun Muftuoglu and Jorge L. Alió -- Ch. 13. 2 Complications of iris-supported phakic IOLs / Antonio A.P. Marinho -- Ch. 13.3 Complications of posterior chamber phakic intraocular lenses / Carlo F. Lovisolo and Fabio Mazzolani -- Ch. 14. 1 Retinal detachment / José Ma Ruiz-Moreno, Jorge L. Alió, and Mohamed H. Shabayek -- Ch. 14.2 Refractive lens exchange and choroidal neovascularization / Emanuel Rosen -- Ch. 14.3 Refractive surprises after cataract post-corneal refractive surgery / Béatrice Cochener and Jean Louis Arne -- Ch. 15.1 Cataract surgery complications of radial keratotomy / Howard Fine, Richard S. Hoffman, Mark Packer, and Laurie Brown -- Ch. 15.2 Complications of conductive keratoplasty / Marguerite B. McDonald -- Ch. 16 Complications of intrastromal corneal ring segments / Mohamed H. Shabayek and Jorge A. Alió -- Ch. 17 Corneal inlays (synthetic keratophakia) / M. Emilia Mulet, Jorge A. Alió, and Michael Knorz -- Ch. 18.1 Predicting the unhappy patient and patient expectations / Nayyirih G. Tahzib and Rudy M.M.A. Nuijts -- Ch. 18.2 Informed consent / James J. Salz -- Ch. 18.3 Effect of refractive surgery on strabismus and binocular vision / Bharavi Kharod and Natalie A. Afshari -- Ch. 19.1 10-year classified review of the peer review literature on excimer laser refractive complications / Takashi Kojima, Tatsuya Ongucci, Joelle Hallak, and Dimitri Azar -- Ch. 19.2 10-year review of the literature on complications of incisional, thermal and lenticular refractive procedures / Tatsuya Ongucci, Takashi Kojima, and Dimitri Azar -- Epilog Preventing complications in refractive surgery: present and future / George Waring III.
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    Introduction -- Study design and planning -- Data definition, forms, and database design -- Computer systems for data management and data entry -- Patient registration -- Local data management systems -- Central quality control of data -- Data management and good clinical practice -- Software tools for trials management -- Follow-up and close-out phase -- Training, education, and documentation -- Clinical trials collaboration models.
  • This book explores the challenges of treating foot complications associated with diabetes,℗ℓ a major challenge for societies the world over. Authors include experienced podiatrists, nurses and doctors,℗ℓ all of whom℗ℓ work in the field of diabetes foot care. The book is divided into prevention and early management, management of major complications, prevention of recurrence and how to structure a team.℗ℓ In each area, the authors describe their practical experiences and discuss how they have addressed clinical challenges. Management of Diabetic Foot Complications provides useful information for anyone responsible for the care of people with diabetes who may be at risk of developing foot complications.
  • Bulimia nervosa / Steven J. Romano -- Counseling patients with bulimia nervosa / Tricia Cook Myers and James E. Mitchell -- Pharmacologic therapy of bulimia nervosa / James I. Hudson, Harrison G. Pope, Jr., and William P. Carter -- Prevention of eating disorders: a nutritional perspective / Cheryl L. Rock -- Anorexia nervosa / Steven J. Romano -- Treatment of anorexia nervosa / L.K. George Hsu -- Pharmacological therapy for anorexia nervosa / Walter H. Kaye -- The Internet and eating disorders / David J. Goldstein -- Etiologies of obesity / Richard L. Atkinson -- Medical consequences of obesity and benefits of weight loss / Lalita Khaodhiar and George L. Blackburn -- Obese patients with binge-eating disorder / Marsha D. Marcus and Michele D. Levine -- Overview and the future of obesity treatment / Lisa Terre, Walker S.C. Poston II, and John P. Foreyt -- The role of physical activity, exercise, and nutrition in the treatment of obesity / Edward T. Mannix ... [et al.]. Lifestyle modification in the treatment of obesity / Anthony N. Fabricatore and Thomas A. Wadden -- Very low-calorie diets / Stephen D. Phinney -- Pharmacotherapy of obesity / George A. Bray -- Combination therapies for obesity / Richard L. Atkinson and Gabriel Uwaifo -- Genetics and potential treatments for obesity / José R. Fernández and David J. Goldstein -- The role of hunger and satiety in weight management / Michael Penn and David J. Goldstein -- Surgical interventions for the management of obesity / Scott A. Shikora, David Smith, and Julie J. Kim -- Clinical experience in a comprehensive weight-management center / Judy Loper and Richard A. Lutes -- The multidisciplinary team in the management of obesity / Patrick Mahlen O'Neil and Sherry Rieder -- The Internet and obesity treatment / David J. Goldstein -- Barriers to treatment / Arthur Frank -- Prevention of obesity / Barbara C. Hansen.
  • Management of Functional Gastrointestinal Disorders in Children presents biopsychosocial theory with respect to six groups of functional disorders: disorders of elimination, vomiting disorders, abdominal pain, infant colic, chronic non-specific diarrhea of infants and toddlers, and failure to thrive. It illustrates, through numerous clinical examples, concepts of management developed during 45 years of practice. A satisfactory clinical outcome for pediatric gastrointestinal disorders often depends on the clinician's ability to discern not only the biological factors in illness, but also the unique cognitive and emotional needs that patients bring to the task of healing. This book provides guidelines for integrating the biopsychosocial model, an approach that has been under-emphasized in the literature until now. It includes naturalistic descriptions of functional gastrointestinal disorders, clinical goals, and the theoretical bases for management techniques. Offering numerous real-world examples and tips, this book serves as a valuable resource for pediatricians, family practitioners, pediatric mental health practitioners, pediatric nurse practitioners, as well as pediatric gastroenterologists.
  • This book is especially focused on the surgical aspect on Gender Dysphoria. Male to female surgery is widely discussed as well as the female to male conversion. Full information on hormone administration and surgical procedures are provided. Mental health issues are also described, as well as ethics, the law and psychosocial issues. The text is extensively referenced and includes numerous photos, tables and figures to clearly illustrate information. Based on collaboration between international experts in transgender health, this book is an essential guide for health care professionals, educators, students, patients and patients? families concerning the psychological, hormonal, surgical and social support of transgender individuals.
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  • The risk of cancer increases with age and the number of older adults seeking treatment is rising dramatically in line with the aging population. The care of older patients differs from that of younger adults because of variation in the biology of the tumor, age-related variation in host physiology, co-morbidity burden and psychosocial issues, which might impact the efficacy and side effects of cancer therapy.Management of Gynecological Cancers in Older Women focuses on treatment strategies of gynecological cancers and provides guidance on the issues specific to older patients, spanning background and epidemiology, special considerations in the care of older women, therapeutics, and psychosocial considerations. This book offers a thorough review of current approaches to treating older gynecological cancer patients, detailing the special issues and considerations involved. The discipline-spanning coverage outlines best practice and proposes topics for future research.The second volume in the Management of Cancer in Older People series, this book will be of interest to all surgical oncologists, medical oncologists, gerontologists, gynecologists and other members of the multidisciplinary team involved in the care of elderly gynecological cancer patients.
  • Management of heart failure v.1-2, 2008.
    Springer
    v.2, 2008 Springer
    v. 1. Medical / edited by Ragavendra R. Baliga, Bertram Pitt, and Michael M. Givertz -- v. 2. Surgical / edited by Jai Raman.
  • This book focuses on the management of hematological cancer and provides guidance on the management issues specific to older patients, spanning background and epidemiology, special considerations in the management of older people, therapeutics and psychosocial considerations. Management of Hematological Cancers in Older People aims to provide an up-to-date review of the literature in each of the major areas relating to the management of older hematological cancer patients, and makes recommendations for best practice and future research. The authors come from a broad geographic spread including the UK, mainland Europe and North America to ensure a worldwide relevance. Management of Hematological Cancers in Older People will appeal to surgical oncologists, medical oncologists and other members of the multidisciplinary team.
  • Management of hypertension in diabetes / Samy I. McFarlane -- Hypertension in diabetes : prevalence, risks and treatment targets / Antonio Coca & Miguel Camafort -- Nonpharmacological management of hypertension in diabetes / Marie-Ève Leblanc, Caroline Rhéaume, Lyne Cloutier, Jean Lefebvre & Paul Poirier -- Pharmacological management of hypertension in diabetes / Tonje A. Aksnes, Sigrid N. Skårn & Sverre E. Kjeldsen -- Role of angiotensin receptor blockers in diabetes / Philippe Akhrass, John N. Makaryus, Amgad N. Makaryus, Arathy Vamadevan & Samy I. McFarlane -- Treatment recommendations and consensus guidelines / Vivencio Barrios Alonso & Carlos Escobar Cervantes.
  • This book aims to provide an up-to-date review of the literature in each of the major areas relating to the management of older lung cancer patients, and makes recommendations for best practice and future research. The authors come from a broad geographic spread including the UK, mainland Europe and North America to ensure a worldwide relevance.
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  • Management of Musculoskeletal Injuries in the Trauma Patient summarizes the most current concepts and clinical practices for the management of the patient with musculoskeletal traumatic injuries. The text covers optimal time frames for stabilization of orthopedic injuries and strategies to mitigate systemic injury while minimizing damage due to pelvic, spine and long bone trauma. The volume covers the gamut of traumatic axial and extremity injuries, including cervico-lumbar-thoracic spine injuries, spinal cord injuries, long bone fractures with special emphasis on the femoral shaft, pelvic and acetabular injuries, open fractures, mangled extremities, upper extremity injuries, combination and severe soft tissues injuries and periarticular fractures. These are discussed in the context of isolated injury and combined with orthopedic injuries of the brain, abdomen, chest and other musculoskeletal injuries. Written by internationally recognized experts, Management of Musculoskeletal Injuries in the Trauma Patient is a valuable resource for orthopedic surgeons.
  • This book pursues a multidisciplinary approach, presenting chapters with updated information on various aspects of treatment for patients with neuroendocrine tumors. Authors have been selected from expert centers in Europe and the United States. The goal of this book is to comprehensively summarize recent data and provide inspiring ideas to optimize the care of patients with neuroendocrine tumors. Neuroendocrine tumors are fascinating multifaceted diseases that can primarily localize in many organs with various presentations. These tumors are rare but their increasing incidence renders likely that physicians caring for cancers may have either already faced or may be certainly exposed to diagnose and/or treat a patient with neuroendocrine tumors. Over the last years, novel therapeutic options have emerged for neuroendocrine tumors, profoundly challenging practices that had previously been the standards for decades. These include - but are not limited to - somatostatin analogues, targeted therapies such as tyrosine kinase and mTOR inhibitors, antiangiogenic compounds, but also peptide-receptor targeted therapy or radioembolization. This changing field has generated novel treatment algorithms to guide medical decisions. To better understand and handle the multidisciplinary approaches that are required for optimizing the care of neuroendocrine tumor patients, physicians are now looking for references from experts and comprehensive reviews summarizing current knowledge on treatments for patients with neuroendocrine tumors.
  • This book provides the reader with a multidisciplinary approach that is state of the art and reflects input from the European Neuroendocrine Tumor Society and the North American Neuroendocrine Tumor Society. In particular, the text focuses on the pathophysiology of neuroendocrine tumors and includes a comprehensive review of the most recent developments in understanding the complex hormone and receptor signaling that is important for the future development of potent pharmacological treatments. The volume reviews the pathological grading and staging systems providing useful clinical information for the treating clinician as well as a useful reference for pathologists. The clinical management of neuroendocrine tumors is reviewed enabling the treating physician to understand the diagnostic approaches to differentiating the various types of neuroendocrine tumors. In addition, the treatments are reviewed in great detail and include novel radiological, surgical, and chemotherapeutic approaches. The reader will utilize this book as both a comprehensive and quick reference guide through the use of diagnostic and treatment algorithms. Written by international experts in their particular field of study, Management of Pancreatic Neuroendocrine Tumors will be of great value to medical oncologists, endocrinologists, gastroenterologists, pathologists, surgeons, and diagnostic and interventional radiologists.
  • The twin epidemics of obesity and type 2 diabetes mellitus (T2DM) continue to affect an ever increasing number of children, adolescents, and young adults. Management of Pediatric Obesity and Diabetes provides healthcare trainees and professionals with practical, comprehensive, and contemporary approaches to the pediatric patient at risk for obesity, T2DM, and related conditions. A unique guide on the subject, this volume provides clinical paradigms for diagnosis and management of pediatric T2DM and related conditions, while succinctly describing state-of-the-art basic and clinical sciences underlying these problems. The chapters in this volume are independent and concise. Each chapter focuses on a key clinical issue or mechanism of disease. Providing practical, data-driven resources based upon the totality of the evidence, this important text helps the reader understand the basics of pediatric obesity and T2DM and implement strategies to prevent and treat obesity and diabetes in children and adolescents. Management of Pediatric Obesity and Diabetes provides health professionals across many areas of research and practice with up-to-date, well-referenced, and comprehensive evidence on identification, treatment, and prevention of these chronic, serious, metabolic diseases in children. This volume will serve the reader as the most authoritative resource in the field to date.
  • Management of Penile Cancer provides a comprehensive and state-of-the-art overview of the major issues specific to the field of penile cancer. The sections of the book are structured to review the overall scope of issues of penile cancer, including diagnosis and staging, surgical approaches, and the treatment of advanced disease. As multidisciplinary care is an integral part of the treatment of penile cancer, this book is unique in the inclusion of collaborating authors from a variety of integrated disciplines, including urology, radiation oncology, medical oncology, and reconstructive surgery. Written by recognized experts in their field, Management of Penile Cancer is a unique and valuable resource in the field of penile cancer, both for those currently in training and for those already in clinical or research practice.
  • The clinical aspects of pericardial disease encompass acute and recurrent pericarditis, pericardial effusion and pericardial tamponade, constrictive pericarditis, and effusive-constrictive pericarditis. These disorders differ not only in clinical presentation but also in the timeline of development, thus management of pericardial disease can be challenging for many clinicians. To assist medical professionals with this often complex area, this book provides an extensive review of pericardial disease evaluation and management in a unified, stepwise pathway-based approach. Management of Pericardial Disease contains a selection of defining clinical images to guide in identification and management of pericardial disease. Fellows, residents, cardiologists, thoracic medicine physicians, cardiothoracic surgeons, radiologists, and intensive care and emergency medicine physicians alike will find this book to be an essential resource for developing the skills and knowledge applicable to managing pericardial disease in patients.
  • Clinical findings and natural history of Prader-Willi syndrome / Merlin G. Butler, Jeanne M. Hanchett, and Travis Thompson -- Diagnostic criteria for Prader-Willi syndrome / Shawn E. McCandless and Suzanne B. Cassidy -- Molecular genetic findings in Prader-Willi syndrome / Karin Buiting and Bernhard Horsthemke -- Laboratory testing for Prader-Willi syndrome / Kristin G. Monaghan and Daniel L. Van Dyke -- Medical considerations in Prader-Willi syndrome / Urs Eiholzer and Phillip D.K. Lee -- Gastrointestinal system, obesity, and body composition / Ann O. Scheimann, Phillip D.K.Lee, and Kenneth J. Ellis -- Growth hormone and Prader-Willi syndrome / Aaron L. Carrel, Phillip D.K. Lee, and Harriette R. Mogul -- Neurodevelopmental and neuropsychological aspects of Prader-Willi syndrome / Barbara Y. Whitman and Travis Thompson -- Speech and language disorders associated with Prader-Willi syndrome / Barbara A. Lewis -- Motor and developmental interventions / Toni Goelz -- Educational considerations for children with Prader-Willi syndrome / Naomi Chedd, Karen Levine, and Robert H. Wharton -- Tools for psychological and behavioral management / Barbara Y. Whitman and Kevin Jackson -- Educational and social issues for adolescents with Prader-Willi syndrome / Barbara J. Goff -- Transition from adolescence to young adulthood: the special case of Prader-Willi syndrome / Ellie Kazemi and Robert M. Hodapp -- Vocational training for people with Prader-Willi syndrome / Steve Drago -- Residential care for adults with Prader-Willi syndrome / Mary K. Ziccardi -- Inpatient crisis intervention for persons with Prader-Willi syndrome / Linda M. Gourash, James E. Hanchett, and Janice L. Forster -- Social work interventions: advocacy and support for families / Barbara Y. Whitman -- A national approach to crisis intervention and advocacy / David A. Wyatt -- Advocacy issues: school discipline and expulsion / Barbara J. Goff -- Advocacy issues: sexuality / Janalee Heinemenn, David A. Wyatt, and Barbara J. Goff.
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  • Epidemiology of Prostate Cancer in Europe / Ruben G. Cremers and Lambertus A. Kiemeney -- Chemoprevention of Prostate Cancer / Bertrand Tombal -- Individual and Mass Screening / Chris H. Bangma, Pim J. van Leeuwen and Monique J. Roobol -- Anatomo-Pathology / Theodorus H. Van der Kwast -- Biomarkers for Prostate Cancer / Gisele H. J. M. Leyten, Peter F. A. Mulders and Jack A. Schalken -- Diagnosis, Clinical Work Up, TNM Classification, Markers / Jean-Luc Descotes and Anne-Sophie Gauchez -- Active Surveillance for Favorable Risk Prostate Cancer: Background, Patient Selection, Triggers for Intervention, and Outcomes / Laurence Klotz -- Open Radical Prostatectomy / Hein van Poppel and Steven Joniau -- Robot-Assisted Radical Prostatectomy / Stefan Carlsson and Nils Peter Wiklund -- Permanent Prostate Brachytherapy / Jan J. Battermann -- High-Dose-Rate Brachytherapy: Indications, Technique, and Results / Alberto Bossi, Rodolfe Verstraet, Lucie Calmels and Pierre Blanchard -- Intensity Modulated Radiotherapy for Prostate Cancer / Olivier Chapet, Corina Udrescu and Ciprian Enachescu -- Combination of Androgen Deprivation Therapy and Radiation Therapy for Locally Advanced and Localized Prostate Cancer / Michel Bolla and Camille Verry -- Postoperative Irradiation: Immediate or Early Delayed? / Dirk Bottke and Thomas Wiegel -- High-Intensity Focused Ultrasound (HIFU) for Prostate Cancer / Albert Gelet, Sebastien Crouzet, Olivier Rouviere and Jean-Yves Chapelon -- Cryotherapy / Matvey Tsivian and Thomas J. Polascik -- Follow-up After Radical Treatments and Relapse / Nicolas Mottet -- First-Line Hormonal Manipulation of Prostate Cancer / Suresh Venugopal and John Anderson -- Resistance to Chemical Castration: Second-Line Hormonal Treatment / Yohann Loriot, Christophe Massard and Karim Fizazi -- Targeted Therapies and Vaccination / Guru Sonpavde and Cora N. Sternberg -- How to Interpret Results? / Laurence Collette -- Management of Prostate Cancer: EAU Guidelines on Screening, Diagnosis and Treatment / Axel Heidenreich -- Better Patients' Perspective / Louis J. Denis.
  • Epidemiology and risk factors / Ranko Miocinovic -- Twenty years and counting : is PSA still useful in 2010? / Haluk Ozen and Sertac Yazici -- Prostate cancer screening : a review of the evidence with clinical practice implications / Timothy J. Wilt -- Beyond PSA : promising new markers for prostate cancer / Leonard Marks -- Hereditary prostate cancer and genetic risk / Adam C. Reese, Graham Casey, and John S. Witte -- Prostate inflammation and prostate cancer / William G. Nelson ... [et al.] -- Molecular progression of prostate cancer : androgens and estrogens / Stephen A. Boorjian and Donald J. Tindall -- The role of obesity and diet in prostate cancer / Jean-Alfred Thomas II and Stephen J. Freedland -- Prostate cancer risk reduction by chemoprevention / Kenneth G. Nepple, Adam S. Kibel, and Gerald L. Andriole -- Current issues in pathologic evaluation / Sara M. Falzarano, Howard S. Levin, and Cristina Magi-Galluzzi -- Optimum prostate biopsy : techniques and strategies / Osama M. Zaytoun and J. Stephen Jones -- The utility of nomograms in routine clinical practice / Carvell T. Nguyen and Michael W. Kattan -- Active surveillance comes of age / Laurence Klotz -- Focal therapy : prostate hemiablation as the first historical treatment model for focal therapy of early stage prostate cancer / Vladimir Mouraviev and Thomas J. Polascik -- Contemporary external beam radiotherapy / Rahul Tendulkar and Kevin Stephans -- Surgery, brachytherapy, or external beam radiation for low- and intermediate-risk disease? / Jay P. Ciezki and Eric A. Klein -- The role for radical prostatectomy in advanced prostate cancer / R. Jeffrey Karnes and Michael L. Blute -- Radiation therapy in the management of locally advanced prostate cancer / Joseph D. Mancias and Anthony L. Zietman -- Clinical implications of measuring quality-of-life in early stage prostate cancer / Peter Chang, Mehrdad Alemozaffar, and Martin G. Sanda -- Treatment modalities of post-prostatectomy incontinence : a historical perspective as well as current therapy options / Christina Ching and Drogo K. Montague -- Management of biochemical recurrence after localized treatment for prostate cancer / Stephen B. Williams and Toni K. Choueiri -- Management of newly diagnosed metastatic disease / C. Lance Cowey and Thomas E. Hutson -- Pitfalls of androgen deprivation therapy / Alicia K. Morgans and Matthew R. Smith -- Current management of castration-resistant prostate cancer (CRPC) / Jorge A. Garcia and Robert Dreicer -- Beta-emitting radiopharmaceuticals and bone metastasis / Oliver Sartor.
  • Clinical spectrum and severity of psoriasis / Meier, M., Sheth, P.B. -- Impact of comorbidities on the management of psoriasis / Gerdes, S., Mrowietz, U. -- Topical treatment of psoriasis / Kamili, Q.u.A., Menter, A. -- Practice of phototherapy in the treatment of moderate-to-severe psoriasis / Nguyen, T. ... [et al.] -- Retinoids, methotrexate and cyclosporine / Dubertret, L. -- Monitoring patients treated with efalizumab or alefacept / Papp, K.A. -- Management of severe psoriasis with TNF antagonists : adalimumab, etanercept and infliximab / Mössner, R., Reich, K. -- Therapies for childhood psoriasis / Trüeb, R.M. -- Management of difficult to treat locations of psoriasis : scalp, face, flexures, palm/soles and nails / Kragballe, K. -- Future perspectives in the treatment of psoriasis / Wippel-Slupetzky, K., Stingl, G.
  • Section 1 CNS tumors -- Germinal tumours of the central nervous system in adult patients -- Atypical and malignant meningiomas -- Primary central nervous system lymphoma -- Treatment of Medulloblastoma in adults -- Cerebellar glioblastoma multiforme -- Chordoma and chondrosarcoma of the skull base -- Primary spinal epidural lymphoma -- Section 2 Heads and neck tumors -- Esthesioneuroblastoma -- Extranodal NK/T-cell lymphoma, nasal-type -- Uncomon tumours of the nasopharynx -- Rare malignant tumours of the larynx and hypopharynx -- Primary orbital lymphoma -- Primary MALT lymphoma of the salivary glands -- Section 3 Gastro-intestinal tumors -- Mucosal melanoma of the upper aero-digestive tract -- Gastrointestinal stromal tumours -- Small cell carcinomas of the gastrointestinal tract -- Small cell carcinomas of the gastrointestinal tract -- Anorectal Melanoma -- Uncommon Hepatobiliary Tumours -- Unusual pancreatic tumours -- Section 4 Genitourinary -- Rare tumours of the renal pelvis and ureter -- Rare tumours of the urethra -- Uncommon bladder cancers -- Neuroendocrine small cell carcinoma of the prostate: A brief review of pathology, clinical characteristics and treatment guidelines -- Uncommon tumours of the testis -- Primary Testicular lymphoma -- Human chorionic gonadotropin-producing seminoma -- Section 5 Gynecological -- Rare ovarian cancers -- Extraovarian primary peritoneal carcinoma -- Uterine papillary serous carcinoma -- Uterine sarcomas and rare endometrial carcinomas -- Uterine sarcomas and rare endometrial carcinomas -- Rare tumours of the uterine cervix -- Tumours of the vagina and tumours of the vulva -- Section 6 Breast -- Invasive breast cancer and ductal carcinoma in situ in young women -- Tubular carcinoma of the breast -- Adenoid cystic carcinoma of the breast -- Primary squamous cell carcinoma of the breast -- Primary breast lymphoma -- Phyllodes tumours of the breast -- Primary breast sarcomas -- Angiosarcoma of the breast -- Male breast cancer -- Section 7 Lung and intrathoracic malignancies -- Primary uncommon tumours of the lung: lymphomas, sarcomas and melanomas -- Thymoma and thymic carcinoma -- Large cell neuroendocrine carcinoma of the lung -- Neuroendocrine tumours of the lung -- Pleural mesothelioma -- Bronchioloalveolar carcinoma and adenocarcinoma with bronchioloalveolar carcinoma features: a clinico-pathological spectrum -- Primary adenoid cystic carcinoma of the trachea and bronchus -- Tracheal cancers -- Section 8 Malignancies of the skin -- Unusual cutaneous malignancies: cutaneous adnexal tumours -- Kaposi's sarcoma -- Dermatofibrosarcoma protuberans (DFSP) -- Merkel cell carcinoma: A challenge in cancer management -- Langerhans cell histiocytosis (LCH) -- Section 9 Other malignancies -- Primary bone lymphoma (osteolymphoma) -- Erdheim-Chester disease -- Solitary plasmacytoma -- Neuroendocrine tumours.
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  • Management of Soft Tissue Sarcoma addresses the diagnosis and best current management of adult soft tissue sarcomas. Edited by world renonwed experts, this book dileneates and discusses each different sarcoma subtype individually -- source other than Library of Congress.
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  • Management of the Patient at High Risk for Breast Cancer provides a state-of-the art review of patients who are at high risk for breast cancer, how to identify them, the tools available for risk assessment and quantification and indications for genetic counseling and testing. The book summarizes the high risk breast imaging options, including newest techniques and schedules. Pathologic evaluation of high risk lesions are featured as well as the management issues surrounding these lesions. The volume also covers the management of concomitant cancer risk and screening strategies.
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  • The risk of cancer increases with age and the number of older adults seeking treatment is rising dramatically in line with the aging population. The care of older patients differs from that of younger adults because of variation in the biology of the tumor, age-related variation in host physiology, co-morbidity burden and psychosocial issues, which might impact the efficacy and side effects of cancer therapy.Management of Urological Cancers in Older People focuses on treatment strategies of urological cancers and provides guidance on the issues specific to older patients, spanning background and epidemiology, special considerations in the care of older people, therapeutics, and psychosocial considerations. This book offers a thorough review of current approaches to treating older urological cancer patients, detailing the special issues and considerations involved. The discipline-spanning coverage outlines best practice and proposes topics for future research.This first volume in the Management of Cancer in Older People series will be of interest to all surgical oncologists, medical oncologists, gerontologists, urologists and other members of the multidisciplinary team involved in the care of elderly urological cancer patients.
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    Cut costs and increase profits -- Guidelines -- Prescription for success -- Staffing for success -- Design decisions -- Trial design -- Exception handling -- Documentation -- Recruiting and retaining patients and physicians -- Computer-assisted data entry -- Data management -- Are you ready? -- Monitoring the trials -- Managing the trials -- Data analysis -- Check.
  • pt. 1. What are food allergens and allergies? -- pt. 2. Allergens in foods - from raw to processed foods -- pt. 3. Assessing allergic risks and practical management of allergens in food.
  • "Managing Bipolar Disorder in Clinical Practice", Third Edition, is an up-to-date, concise practical handbook developed with the clinician in mind. Including the most recent clinical guidelines, including the British Association for Psychopharmacology (BAP) and Canadian Network for Mood and Anxiety Treatments (CANMAT) guidelines, this handbook is intended to highlight every major aspect of this serious mental health disorder, including assessment, treatment, long-term management, and recent developments.
  • Breathlessness Management in Clinical Practice presents evidence-based practical techniques for helping the breathless patient with advanced disease of any aetiology used in the Cambridge Breathlessness Intervention Service (CBIS). This book will help individuals in the multidisciplinary team both manage breathlessness in their current clinical setting and describe the breathlessness service model which can be adapted for use in any situation. It uses a model of care based on interventions for breathing, thinking and functioning. Breathlessness Management in Clinical Practice is an invaluable resource for those working in the respiratory medicine, oncology and cardiology and other specialties where breathlessness is commonly managed although less recognised like nephrology and neurology. It will be of help to occupational therapists, physiotherapists and specialist nurses as well as physicians. It will also be of interest to anyone who wishes to increase their knowledge of the advances in evidence that now enable clinicians to offer much improved care for those suffering with frightening symptom of breathlessness.
  • Managing Cancer Breakthrough Pain is a comprehensive review of cancer breakthrough pain (cBTP) and rapid-onset opioids (ROO), the only treatment approved for cBTP episodes. The book was originally commissioned due to the current rapid growth of the ROO market and the epidemic of ROO abuse. This book will review the historical background and definitions of cBTP and ROOs, assessment methods to determine types of cBTP, US- and EU-approved ROOs, case studies (which will provide practical applications of ROO treatment options), ROO abuse and screening methods, and the FDA-mandated TIRF REMS Access program (Transmucosal Immediate Release Fentanyl Risk Evaluation and Mitigation Strategies Access program). Busy healthcare professionals who have a basic understanding of cancer pain but want to learn more about cBTP and ROOs will benefit from this concise guide that will help them quickly understand the complexities of cBTP episodes and ROOs.
  • Managing Common Interventional Radiology Complications: A Case Based Approach is an easy-to-use manual that will help trainees and practising radiologists by providing cases which cover most of the complications that a general interventionalist may encounter in normal practice. The cases are presented succinctly but thoroughly, so that the reader is equipped to manage the complication immediately. Managing Common Interventional Radiology Complications: A Case Based Approach aims to teach the range of procedures involved in interventional radiology, and focuses on the complications that can arise in the process.
  • The book includes recommendations for COPD from published guidelines (eg, the GOLD, ATS, and NICE guidelines) and presents them in the context of relevant clinical treatment issues. This is an in-depth guide on the management of COPD, concentrating on the impact of COPD on a patient as well as how healthcare professionals can intervene and educate the patient at an early stage and thereby slow the onset of severe symptoms.
  • Classification, causes, and epidemiology. Different types of depression ; Causes of depression ; Epidemiology and natural history -- Depression in different types of patients. Depression in children ; Depression in elderly people ; Depression in women ; Depression in patients with comorbid medical conditions -- Diagnosis. Signs and symptoms of depression ; Differential diagnosis ; The patient examination and interview ; Laboratory tests for co-occurring illnesses -- Principles of therapy. Goals of treatment ; Treatment options ; Choice of treatment ; Practicalities of treatment ; Factors affecting response to treatment -- Medications. Selective serotonin reuptake inhibitors ; Serotonin and norepinephrine reuptake inhibitors ; Monoamine receptor antagonist drugs ; Norepinephrine reuptake inhibitors ; Dopamine reuptake inhibitors ; Tricyclic antidepressants ; Monoamine oxidase inhibitors ; Other drugs ; Specific adverse effects of antidepressants -- Other treatments. Psychotherapy for depression ; Combination psychotherapy and psychopharmacotherapy for depression ; Physical treatments ; Lifestyle and complementary therapies -- Management of treatment nonresponse. Assessment and principles of management ; Definitions: treatment nonresponse and treatment-resistant depression ; Medication strategies ; Psychological treatment strategies ; Physical treatment strategies -- Continuation and maintenance treatment. Goals of continuation/maintenance treatment ; Phases of treatment ; Medication ; Psychological treatments ; Physical treatments ; Risk factors for relapse and recurrence ; Longer-term treatment in practice.
  • Managing diabetes 2012
    Springer
    Managing Diabetes is a up-to-date, comprehensive showcase of the current pharmaceutical trends in treating diabetes and provides a unbiased, inclusive discussion of current and emerging treatments by well-known experts in the field.
  • "Gout has been a well-known disease for over 2000 years, and is the most common cause of joint inflammation in adult males. It has become apparent that no therapeutic target based on hyperuricemia outcome had been defined. Very few controlled trials were available to test the efficacy and safety of treatments, and no research on diagnosis and management had been done despite data showing that patients with gout were generally improperly treated even in the hands of specialists. In the last 10 years, good-quality evidence on gout impact and management has grown exponentially, renal transporters have been recently identified, and a number of new drugs have been approved or are under current development. This handbook discusses these developments and the future of gout treatment, which now looks promising."--Publisher's website.
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    Healthcare in the United States -- Types and structures of health services organizations and health systems -- Healthcare technology -- Ethical and legal environment -- The practice of management in health services organizations and health systems -- Managerial problem solving and decision making -- The quality imperative -- Strategizing -- Marketing -- Controlling and allocating resources -- Designing -- Leading -- Communication.
  • As the number of people aged 65 years and above rises, physicians are increasingly confronted by elderly patients with impaired renal function, altered drug metabolism and multiple comorbidities. This book examines in detail the nature of renal injury in the elderly and its optimal management. A wide range of key topics are covered, including end-stage renal disease, diabetic nephropathy, acute kidney injury, drug metabolism and renal toxicity, dialysis and its complications and the use of renal transplantation. In addition, the assessment of glomerular filtration rate in the elderly and the role of novel renal biomarkers are carefully examined. Quality of life issues, the significance of other age-related medical problems and end of life care are also discussed. This book will be of value not only to nephrologists but also to general practitioners, medical students, intensivists, cardiologists, pharmacologists and those working in related specialties.
  • Low back pain is described as a very common condition that tends to affect about 70% of the population at some point in time with varying degrees of symptom severity. Although definitions vary, sciatic pain is generally defined as back-related pain radiating to the leg (normally below the knee and into the foot and toes) and is one of the commonest variations of low back pain. Patients with sciatica typically experience a more persistent and severe type of pain, a less favorable outcome, consume more healthcare resources and have more prolonged disability and absence from work than those with low back pain alone. Managing Sciatica and Radiculopathies in Primary Care Practice provides a comprehensive, up-to-date overview of the subject and key information for primary care practitioners about low back pain in patients, including definitions and causes, current management approaches, diagnostic and treatment algorithms, as well as clinical practice guidelines.
  • Diagnosis of Skin Cancer -- Histopathology of Skin Cancer -- Basal Cell Carcinoma -- Squamous Cell Carcinoma In Situ -- Invasive Squamous Cell Carcinoma of the Skin -- Cutaneous Malignant Melanoma -- Merkel Cell Carcinoma -- Cutaneous Lymphomas -- Kaposi Sarcoma -- Other Skin Cancers. Fibrohistiocytic Skin Cancers and Extramammary Paget's Disease -- Skin Cancer Under Special Circumstances -- Skin Cancer Prevention.
  • Healing -- Sports massage -- Taping in sport -- Physical training and injury -- Exercise therapy -- First contact management -- Lower limb motion during walking, running, and jumping -- The hip and thigh -- The knee -- The shin -- The ankle -- The foot -- The lumbar spine -- The thorax and thoracic spine -- The cervical spine -- Facial injury -- The shoulder -- The elbow -- The wrist and hand.
  • Managing the Injured Athlete is an innovative clinically-focused pocketbook which aims to support the clinician out in the field, helping answer clinical queries and solve problems when there may be nothing else to refer to. It focuses on developing the clinician's clinical reasoning skills, recognizing that patterns of clinical presentation are the key to problem-solving and formulating a diagnosis. As well as covering assessment, treatment and rehabilitation, the experienced authors discuss the clinician's role within a team, athlete confidentiality, travelling with athletes, drugs and doping issues, working in different climates and return to play considerations. Throughout the pocketbook patterns of positive findings are given as a key to indicate how frequently clinicians can expect to come across certain subjective and objective markers for a given condition. Starts from the point of subjective and objective examination - assessment not diagnosis Highlighted evidence points to solid literature supporting the intervention described Clinical Tips and Further Reading Case studies demonstrate principles of injury rehabilitation in practice Handy, durable format small enough to use in the field and for quick reference.
  • The basics of managing a laboratory animal facility -- The organizational environment -- The management of human resources -- Managing financial resources -- Management of information resources -- Time management -- Leadership.
  • Headache for history buffs -- When is a headache more than "just a headache?": the secondary headaches -- The primary headache syndromes: when is a headache "just a headache?" -- The pharmacologic treatment of migraine -- Nonpharmacologic treatment of migraine -- Your visit to the doctor -- What to expect -- Append. Grant's migraine -- Migraine myths -- Baseline headache questionnaire -- Headache diary -- Medications previously tried for migraine: treatment.
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    Vol. 1. -- Part I - Basic principles in the diagnosis and management of infectious diseases -- Microbial virulence factors -- Host defense mechanisms -- Epidemiology of infectious diseases -- Clinical microbiology -- Anti-infective therapy -- Part II - Major clinical syndromes -- Fever -- Upper respiratory tract infections -- Pleuropulmonary and bronchial infections -- Urinary tract infection -- Sepsis -- Intra-abdominal infection -- Cardiovascular infections -- Central nervous system infections -- Skin and soft tissue infections -- Gastrointestinal infections and food poisoning -- Bone and joint infections -- Diseases of the reproductive organs and sexually transmitted diseases -- Eye infections -- Hepatitis -- Acquired immunodeficiency syndromes -- Miscellaneous syndromes -- Vol. 2. -- Part III - Infectious diseases and their etiologic agents -- Viral diseases -- Prion diseases -- Chlamydial diseases -- Mycoplasma diseases -- Rickettsioses and ehrlichioses -- Bacterial diseases -- Mycoses -- Protozoal diseases -- Diseases due to toxic algae -- Diseases due to helminths -- Ectoparasitic diseases -- Diseases of unknown etiology -- Part IV - Special problems -- Nosocomial infections -- Infections in special hosts -- Surgical- and trauma-related infections -- Immunization -- Biodefense -- Zoonoses -- Protection of travelers -- The Internet.
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    Conceptualizing manic-depressive illness: the bipolar-unipolar distinction and the development of the manic-depressive spectrum -- Clinical description -- Diagnosis -- Course and outcome -- Epidemiology -- Children and adolescents -- Comorbidity -- Suicide -- Neuropsychology -- Personality, personality disorders, and interpersonal functioning -- Assessment -- Creativity -- Genetics -- Neurobiology -- Neuroanatomy and neuroimaging -- Sleep and circadian rhythms -- Fundamentals of treatment -- Medical treatment of hypomania, mania, and mixed states -- Medical treatment of depression -- Maintenance medical treatment -- Medication adherence -- Psychotherapy -- Treatment of children and adolescents -- Treatment of comorbidity -- Clinical management of suicide risk.
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  • Let a "who's who" of foot and ankle surgeons take your skills to the next level! Drs. Coughlin, Saltzman, and Anderson bring you state-of-the-art, comprehensive coverage of the full range of foot and ankle disorders. Expect the best from this revised "classic" work refreshed for a new generation in one robust multimedia resource. Achieve the best possible outcomes with authoritative answers on every major aspect of the treatment and management of foot and ankle disorders and diseases! With content covering biomechanics, examination, diagnosis, non-operative and operative treatment, and post-operative management, you have all the guidance you need to offer optimal care to your patients.
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  • 2014 ClinicalKey
    From the difficult to diagnose to the difficult to treat, Manson's Tropical Diseases prepares you to effectively handle whatever your patients may have contracted. Featuring an internationally recognized editorial team, global contributors, and expert authors, this revised and updated medical reference book provides you with the latest coverage on parasitic and infectious diseases from around the world. Incorporate the latest therapies into your practice, such as recently approved drugs and new treatment options.Find what you need easily and apply it quickly with highlighted key information, convenient boxes and tables, extensive cross-referencing, and clinical management diagrams.
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    Pt. 1. La Muestra; El Examen microscópico.--pt. 2. El Cultivo del Mycobacterium tuberculosis.--pt. 3. Sensibilidad del Mycobacterium tuberculosis a lsa drogas; La Identificación de micobacterias.--pt. 4. La Organización de los laboratorios de bacteriología de la tuberculosis; medidas de seguridad.
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  • "WHO has developed this manual in order to strengthen the laboratory diagnosis and virological surveillance of influenza infection by providing standard methods for the collection, detection, isolation and characterization of viruses"--Publisher's description.
  • Photographic Documentation in Aesthetic and Plastic Surgery -- Informed Consent in Aesthetic and Plastic Surgery -- Rhinoplasty -- Rhytidectomy -- Eyelid Surgery -- Blepharoplasty -- Otoplasty -- Breast Surgery -- Brachioplasty -- Abdominoplasty -- Thigh and Buttock Lift -- Liposuction -- Hair Transplantation -- Adjuvant Therapies, Including Laser Surgery -- Aesthetic Surgery: Quo Vadis.
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    Introduction to the immune system / Lori Broderick, Taylor A. Doherty, and David Broide -- Immediate hypersensitivity : approach to diagnosis / Sarbjit S. Saini and Nkiruka Erekosima -- Aeroallergens and environmental factors / William Neaville, Robert Ausdenmoore, and Robert K. Bush -- Rhinitis / Candace Bouler Anz and Mark S. Dykewicz -- Sinusitis, nasal polyps, and otitis media / Ricardo A. Tan and Jonathan Corren -- Immunotherapy for inhalant allergens / Harold S. Nelson -- Allergic and immunologic disorders of the eye / Leonard Bielory -- Asthma diagnosis / Stephen C. Lazarus -- Asthma treatment / Joel M. Hartman ... [et al.] -- Immunologic diseases of the lung / Shefalee Amin, Michelle Zeidler, and Eric Kleerup -- Atopic dermatitis and contact dermatitis / Mark Boguniewicz, Marcella Aquino, and Luz Fonacier -- Urticaria and angioedema / Jeffrey R. Stokes and Mark H. Moss -- Anaphylaxis / Phil Lieberman and Debendra Pattanaik -- Insect allergy / David B. K. Golden -- Drug allergy / David A. Khan -- Allergic and non-allergic reactions to food / Stephen R. Boden and A. Wesley Burks -- Eosinophilic gastrointestinal disorders / Terri F. Brown-Whitehorn ... [et al.] -- Primary immunodeficiency diseases / Shradha Agarwal and Charlotte Cunningham-Rundles -- Approach to the patient with recurrent infections / Zuhair K. Ballas -- Diagnostic immunology / Thomas A. Fleisher, Joao Bosco Oliveira, and Jack J. H. Bleesing -- Adverse responses to vaccines / John M. Kelso -- Complementary medicine in allergy and immunology / Timothy Ryan Mainardi and Leonard Bielory -- Building related illness / Jessica Savage and Robert A. Wood.
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  • Introduction to anesthesiology -- Monitoring -- Equipment and procedures -- Intraoperative fluid management and blood component therapy -- Neuraxial and regional anesthesia -- Pharmacology -- Anesthesia and comorbid diseases -- Pediatric anesthesia -- Anesthetic concerns in subspecialty anesthesia -- Postoperative concerns in anesthesia -- Atlas of anesthesia procedures -- Atlas of transesophageal echocardiography -- Atlas of peripheral nerve block procedures.
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  • V. 1: Introduction to the 11th Edition of the Manual of Clinical Microbiology -- Microscopy -- Laboratory Detection of Bacteremia and Fungemia -- Systems for Identification of Bacteria and Fungi -- Automation and Design of the Clinical Microbiology Laboratory -- Molecular Microbiology -- Immunoassays for Diagnosis of Infectious Diseases -- Prevention of Health Care-Associated Infections -- Investigation of Disease Outbreaks -- Molecular Epidemiology -- Procedures for the Storage of Microorganisms -- Prevention of Laboratory-Acquired Infections -- Decontamination, Disinfection, and Sterilization -- Biothreat Agents -- The Human Microbiome -- Microbial Genomics and Pathogen Discovery -- Taxonomy and Classification of Bacteria -- Specimen Collection, Transport, and Processing: Bacteriology -- Reagents, Stains, and Media: Bacteriology -- General Approaches to Identification of Aerobic Gram-Positive Cocci -- Staphylococcus, Micrococcus, and Other Catalase-Positive Cocci -- Streptococcus -- Enterococcus -- Aerococcus, Abiotrophia, and Other Aerobic Catalase-Negative, Gram-Positive Cocci -- General Approaches to the Identification of Aerobic Gram-Positive Rods -- Bacillus and Other Aerobic Endospore-Forming Bacteria -- Listeria and Erysipelothrix -- Coryneform Gram-Positive Rods -- Nocardia, Rhodococcus, Gordonia, Actinomadura, Streptomyces, and Other Aerobic Actinomycetes -- Mycobacterium: General Characteristics, Laboratory Detection, and Staining Procedures -- Mycobacterium: Laboratory Characteristics of Slowly Growing Mycobacteria -- Mycobacterium: Clinical and Laboratory Characteristics of Rapidly Growing Mycobacteria -- Approaches to the Identification of Aerobic Gram-Negative Bacteria -- Neisseria -- Aggregatibacter, Capnocytophaga, Eikenella, Kingella, Pasteurella, and Other Fastidious or Rarely Encountered Gram-Negative Rods -- Haemophilus -- Escherichia, Shigella, and Salmonella -- Klebsiella, Enterobacter, Citrobacter, Cronobacter, Serratia, Plesiomonas, and Other Enterobacteriaceae -- Yersinia -- Aeromonas -- Vibrio and Related Organisms -- Pseudomonas -- Burkholderia, Stenotrophomonas, Ralstonia, Cupriavidus, Pandoraea, Brevundimonas, Comamonas, Delftia, and Acidovorax -- Acinetobacter, Chryseobacterium, Moraxella, and Other Nonfermentative Gram-Negative Rods -- Bordetella and Related Genera -- Francisella -- Brucella -- Bartonella -- Legionella -- Approaches to Identification of Anaerobic Bacteria -- Peptostreptococcus, Finegoldia, Anaerococcus, Peptoniphilus, Veillonella, and Other Anaerobic Cocci -- Propionibacterium, Lactobacillus, Actinomyces, and Other Non-Spore-Forming Anaerobic Gram-Positive Rods -- Clostridium -- Bacteroides, Porphyromonas, Prevotella, Fusobacterium, and Other Anaerobic Gram-Negative Rods -- Algorithms for Identification of Curved and Spiral-Shaped Gram-Negative Rods -- Campylobacter and Arcobacter -- Helicobacter -- Leptospira -- Borrelia -- Treponema and Brachyspira, Human Host-Associated Spirochetes -- General Approaches to Identification of Mycoplasma, Ureaplasma, and Obligate Intracellular Bacteria -- Mycoplasma and Ureaplasma -- Chlamydiaceae -- Rickettsia and Orientia -- Ehrlichia, Anaplasma, and Related Intracellular Bacteria -- Coxiella -- Tropheryma whipplei -- Antibacterial Agents -- Mechanisms of Resistance to Antibacterial Agents -- Susceptibility Test Methods: General Considerations -- Susceptibility Test Methods: Dilution and Disk Diffusion Methods -- Antimicrobial Susceptibility Testing Systems -- Special Phenotypic Methods for Detecting Antibacterial Resistance -- Susceptibility Test Methods: Fastidious Bacteria -- Susceptibility Test Methods: Anaerobic Bacteria -- Susceptibility Test Methods: Mycobacteria, Nocardia, and Other Actinomycetes -- Molecular Detection of Antibacterial Drug Resistance. V. 2: Taxonomy and Classification of Viruses -- Specimen Collection, Transport, and Processing: Virology -- Reagents, Stains, Media, and Cell Cultures: Virology -- Algorithms for Detection and Identification of Viruses -- Human Immunodeficiency Viruses -- Human T-Cell Lymphotropic Viruses -- Influenza Viruses -- Parainfluenza and Mumps Viruses -- Respiratory Syncytial Virus and Human Metapneumovirus -- Measles and Rubella Viruses -- Enteroviruses and Parechoviruses -- Rhinoviruses -- Coronaviruses -- Hepatitis A and E Viruses -- Hepatitis C Virus -- Gastroenteritis Viruses -- Rabies Virus -- Arboviruses -- Hantaviruses -- Arenaviruses and Filoviruses -- Herpes Simplex Viruses and Herpes B Virus -- Varicella-Zoster Virus -- Human Cytomegalovirus -- Epstein-Barr Virus -- Human Herpesviruses -- Adenoviruses -- Human Papillomaviruses -- Human Polyomaviruses -- Parvovirus B19 and Bocaviruses -- Poxviruses -- Hepatitis B and D Viruses -- Transmissible Spongiform Encephalopathies -- Antiviral Agents -- Mechanisms of Resistance to Antiviral Agents -- Susceptibility Test Methods: Viruses -- Taxonomy and Classification of Fungi -- Specimen Collection, Transport, and Processing: Mycology -- Reagents, Stains, and Media: Mycology -- General Approaches for Direct Detection and Identification of Fungi -- Candida, Cryptococcus, and Other Yeasts of Medical Importance -- Pneumocystis -- Aspergillus and Penicillium -- Fusarium and Other Opportunistic Hyaline Fungi -- Agents of Systemic and Subcutaneous Mucormycosis and Entomophthoromycosis -- Histoplasma, Blastomyces, Coccidioides, and Other Dimorphic Fungi Causing Systemic Mycoses -- Trichophyton, Microsporum, Epidermophyton, and Agents of Superficial Mycoses -- Curvularia, Exophiala, Scedosporium, Sporothrix, and Other Melanized Fungi -- Fungi Causing Eumycotic Mycetoma -- Mycotoxins -- Lacazia, Lagenidium, Pythium, and Rhinosporidium -- Microsporidia -- Antifungal Agents -- Mechanisms of Resistance to Antifungal Agents -- Susceptibility Test Methods: Yeasts and Filamentous Fungi -- Taxonomy and Classification of Human Parasitic Protozoa and Helminths -- Specimen Collection, Transport, and Processing: Parasitology -- Reagents, Stains, and Media: Parasitology -- General Approaches for Detection and Identification of Parasites -- Plasmodium and Babesia -- Leishmania and Trypanosoma -- Toxoplasma -- Pathogenic and Opportunistic Free-Living Amebae -- Intestinal and Urogenital Amebae, Flagellates, and Ciliates -- Cystoisospora, Cyclospora, and Sarcocystis -- Cryptosporidium -- Nematodes -- Filarial Nematodes -- Cestodes -- Trematodes -- Less Common Helminths -- Arthropods of Medical Importance -- Antiparasitic Agents -- Mechanisms of Resistance to Antiparasitic Agents -- Susceptibility Test Methods: Parasites.
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    Introduction to the ninth edition of the Manual of clinical microbiology -- Laboratory management -- Laboratory design -- Laboratory consultation, communication, and information systems -- General principles of specimen collection and handling -- Procedures for the storage of microorganisms -- Decontamination, disinfection, and sterilization -- Prevention and control of laboratory-acquired infections -- Laboratory detection of potential agents of bioterrorism -- Infection control epidemiology and clinical microbiology -- Laboratory procedures for the epidemiological analysis of microorganisms -- Investigation of foodborne and waterborne disease outbreaks -- Microscopy -- Principles of stains and media -- Manual and automated systems for detection and identification of microorganisms -- Molecular detection and identification of microogranisms -- Susceptibility testing instrumentation and computerized expert systems for data analysis and interpretation -- Immunoassays for the diagnosis of infectious diseases -- Taxonomy and classification of bacteria -- Specimen collection, transport, and processing: bacteriology -- Reagents, stains, and media : bacterialogy -- Algorithm for identification of aerobic gram-positive cocci -- Algorithm for identification of aerobic gram-positive rods -- Algorithms for identification of aerobic gram-negative bacteria -- Algorithm for identification of anaerobic bacteria -- Aglorithms for indentification of curved and spiral-shaped gram-negative rods -- Algorithms for identification of mycoplasma, ureaplasma, and obligate intracellular bacteria -- Staphylococcus, micrococcus, and other catalase-positive cocci -- Streptococcus -- Enterococcus -- Aerococcus, abiotrophia, and other aerobic catalase-negative, gram-positive coci -- Bacillus and other aerobic endospore-forming bacteria -- Listeria and erysipelothrix -- Coryneform gram-positive rods -- Nocardia, rhodoccus, gordonia, actinomadura, streptomyces,and other aerobic actinomycetes -- Mycobacterium : general characteristcs, laboratory detection, and staining procedures -- Mycobacterium : laboratory characteristcs of slowly growing mycobacteria -- Mycobacterium : clinical and laboratory characteristics of rapidly growing mycobacteria -- Neisseria -- Actinobacillus, capnocytophaga, eikenella, kingella, pasteurella, and other fastidious or rarely encountered gram-negative rods -- Haemophilus -- Enterobacteriaceae: introduction and identification -- Escherichia, shigella, and salmonella -- Yersinia -- Klebsiella, enterobacter, citrobacter, serratia, pleiomonas, and other enterobacteriaceae -- Aeromonas -- Vibrio and related organisms -- Pseudomonas -- Bukholderia, stenotrophomonas, ralstonia, cupriavidus, pandoraea, brevundimonas, comamonas, delftia, and acidovorax -- Acinetobacter, achromobacter, chryseobacterium, moraxella, and other nonfermentive gram-negative rods -- Bordetella -- Francisella and brucella -- Legionella -- Bartonella -- Peptostreptococcus, finegoldia, anaerococcus, peptoniphilus, veillonella, and other anerobic cocci -- Propionibacterium, lactobacillus, actinomyces, and other non-spore-forming anaerobic gram-positive rods -- Clostridium -- Bacterioides, porphyromonas, prevotella, fusobacterium, and other anaerobic gram-negative rods -- Campylobacter and arcobacter -- Helicobacter -- Leptospira -- Borrelia -- Treponema and other human host-associated spirochetes -- Mycoplasma and ureaplasma -- Chlamydia and chlamydophila -- Rickettsia and orientia -- Ehrlichia, anaplasma, and related intracellular bacteria -- Coxiella -- Tropheryma -- Antibacterial agents -- Mechanisms of resistance to antibacterial agents -- Susceptibility test methods: general considerations -- Susceptibility test methods: dilution and disk diffusion methods -- Special phenotypic methods for detecting antibacterial resistance -- Susceptibility test methods: fastidious bacteria -- Susceptibility test methods: anaerobic bacteria -- Suseptibility test methods : mycobacteria, nocardia, and other actinomycetes -- Detection and characterization of antimicrobial reistance genes in pathogenic bacteria -- Taxonomy and classification of viruses -- Specimen collection, transport, and processing : virology -- Reagents, stains, media, and cell lines : virology -- Algorithms for detection and identification of viruses -- Human immunodeficiency viruses -- Human T-cell lymphotropic virus types 1 and 2 -- Influenza viruses -- Parainfluenza and mumps viruses -- Respiratory syncytial virus and human metapneumovirus -- Measles and rubella viruses -- Enteroviruses and parechoviruses -- Rhinoviruses -- Coronaviruses -- Hepatitis A and E viruses -- Heptatitis C and G viruses -- Rotaviruses, caliciviruses, astrofiruses, enteric adenoviruses, and other diarrheic viruses -- Rabies virus -- Hendra and nipah viruses -- Arboviruses -- Hantaviruses -- Arenaviruses and filoviruses -- Herpes simplex viruses and herpes B virus -- Varicella-zoster virus -- Human cytomegalovirus -- Epstein-Barr virus-- Human herpesviruses 6, 7, and 8 -- Adenoviruses - Human papillomaviruses -- Human polyomaviruses -- Human parvoviruses -- Poxviruses -- Hepatitis B and D viruses -- Transmissible spongiform encephalopathies -- Antiviral agents -- Mechanisms of resistance to antiviral agents --- Suseptibility test methods: viruses -- Taxonomy and classification of fungi -- Specimen collection, transport, and processing : mycology -- Reagents, stains, and media : mycology -- Algorithms for detection and identification of fungi -- Candida, cryptococcus, and other yeasts of medical importance -- Pneumocystis -- Aspergillus, fusarium, and other opportunisitc moniliaceous fungi -- Rhizopus, rhizomucor, absidia, and other agents of systemic and subcutaneous zygomycoses -- Histoplasma, blastomyces, coccidioides, and other dimorphic fungi causing systemic mycoses -- Trichophyton, microsporum, epidermophyton, and agents of superficial mycoses -- Bipolaris, exophiala, scedosporium, sporothrix, and other dematiaceous -- Fungi causing eumycotic mycetoma -- Mycotoxins -- Lacazia pythium, and rhinosporidium -- Antifungal agents -- Mechanisms of resistance to antifungal agents -- Susceptibility test methods : yeasts and filamentous fungi -- Taxonomy and classification of human parasites -- Specimen collection, transport, and processing : parasitology -- Reagents, stains, and media : parasitology -- Algorithms for detection and identification of parasites -- Plasmodium and babesia -- Leishmania and trypanosoma -- Toxoplasma -- Pathogenic and opportunistic free-living amebae -- Intestinal and urogenital amebae, flagellates, and ciliates -- Isopora, cyclospora, and sarcocystis -- Cryptosporidium -- Microsporidia -- Nematodes -- Filarial nematodes -- Cestodes -- Trematodes -- Less common helminths -- Arthropods of medical importance -- Antiparasitic agents -- Mechanisms of resistance to antiparasitic agents -- Susceptibility test methods: parasites.
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  • Manual of Coronary Chronic Total Occlusion Interventions: A Step-by-Step Approach is a practical, easy to read reference for coronary chronic total occlusion interventions (CTO). Written by recognized national and international experts in the field, this reference compiles the steps necessary to preform, pitfalls to watch out for, and troubleshooting needed for coronary chronic total occlusion interventions (CTO). A practical, case-oriented and easy to read reference with illustrations and step-by-step guidance for coronary chronic total occlusion interventions (CTO).Includes expert guidance reviewed by leaders in the field with both large clinical experience with high success rates and extensive experience proctoring CTOs in multiple clinical centers.
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  • Coding -- Hair disorders -- Nail disorders -- Pediatric dermatology -- Procedural dermatology -- Med toxicology monitoring. General derm.
  • Manual of Diagnostic and Therapeutic Techniques for Disorders of Deglutition is a comprehensive multidisciplinary text bringing together the research and practice of deglutition. This book is designed as a diagnostic and therapeutic reference for swallowing clinicians from such diverse backgrounds as gastroenterology, speech language pathology, otolaryngology, rehabilitation medicine, radiology and related fields. Manual of Diagnostic and Therapeutic Techniques for Disorders of Deglutition covers information on state-of-the-art diagnostic and therapeutic modalities through contributions from 28 innovators and master clinicians for the benefit of patients and providers alike. It concisely organizes the wealth of knowledge into one comprehensive information platform.This book is an essential reference for all deglutologists, clinicians, and researchers in their areas of expertise.
  • From the Publisher: Prepared by the faculty of the National Emergency Airway Management Course, this manual is an expert, practical guide to emergency airway management in any adult or pediatric patient. It offers step-by-step instructions on techniques, drug administration, and prevention and management of complications and includes a complete section on difficult clinical scenarios. The book is packed with easy-to-follow algorithms and diagrams and helpful mnemonics. Each of the Third Edition's chapters includes improved full-color illustrations and updated evidence-based analyses of procedures. A new section geared to the prehospital setting presents current National Association of Emergency Medical Technicians guidelines, including alternative airway devices.
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  • This textbook explores the latest trends in enhanced recovery from colorectal surgery, covering post-surgical fluid management and more, with examples of enhanced recovery pathways and tips on pain control, feeding, mobilisation and criteria for discharge.
  • The Manual of Geriatric Anesthesia is a practical guide for physicians, residents, and students interested in the care of the elderly patient undergoing surgery. Although primarily written for anesthesiologists, other perioperative physicians and nurses will also find the information highly valuable. Highlights of the text include concise and clear discussions of preoperative assessment, anesthetic administration, the immediate postoperative care, as well as the more classic 'geriatric' topics such as the hip fracture patient, cataract surgery, postoperative delirium, dementia, ethics and end of life care. Clinical geriatric principles are woven into the text so that the reader can develop skills in geriatrics and develop a broader understanding of terminology and principles used in geriatric medicine.
  • This book is designed as an easily readable manual that will be of great practical value for radiology and otolaryngology residents during their clinical rotations. Key facts on head and neck imaging are presented in short chapters written in an easily readable style. Line drawings are used to illustrate key concepts, and tables, checklists, and algorithms will enable the readers to arrive at a quick diagnosis. In addition, emphasis is placed on clinical pearls that will assist them in preparing suitable reports. The Manual of Head and Neck Imaging is sized to allow residents to read it completely within a matter of days, and it will also serve as an ideal quick reference guide as different clinical situations arise.
  • Ablative tumor surgery of the head and neck region often results in severe cosmetic and functional deformities. In these cases, microvascular free-tissue transfer enables three-dimensional reconstruction of head and neck defects. The selection of adequate donor tissue and a profound knowledge of the human anatomy and the various harvesting techniques are paramount in ensuring successful reconstruction. Reflecting current surgical approaches, this book presents the most frequently used flaps in head and neck surgery, including detailed overviews as well as their respective pearls and pitfalls. Moreover, each section contains a synopsis and pre-operative checklist. The overlay-technique merges high-quality-photographs with drawings and precisely illustrates the step-to-step descriptions of the different flap harvesting techniques, making this manual in pocket size an unique and accessible reference for both doctors in training and specialists in the field of otolaryngology, head and neck, plastic, maxillofacial and skull base surgery.
  • Making the transition to healthcare and physician leadership -- The PACT system for strategic leadership communication -- A healthcare leader's guide to people management -- Dealing with politics, problems, and process -- Practical strategy for planning -- Motivation, communication, and negotiation -- Maximizing team action and individual performance -- Encouraging creativity and innovation -- Education and development strategies -- Applying the C-formula: strategies for staff engagement.
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  • Diagnostic testing -- Blood studies : hematology and coagulation -- Urine studies -- Stool studies -- Cerebrospinal fluid studies -- Chemistry studies -- Microbiologic studies -- Immunodiagnostic studies -- Nuclear medicine studies -- X-ray studies -- Cytologic, histologic, and genetic studies -- Endoscopic studies -- Ultrasound studies -- Pulmonary function, arterial blood gases (abgs), and electrolyte studies -- Prenatal diagnosis and tests of fetal well-being -- Special diagnostic, special specimen collection, and postmortem studies.
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    Fetal assessment and prenatal diagnosis -- Diabetes mellitus -- Thyroid disorders -- Preeclampsia and related conditions -- Resuscitation in the delivery room -- Birth trauma -- The high-risk newborn: anticipation, evaluation, management, and outcome -- Assessment of the newborn history and physical examination of the newborn -- Care of the well newborn -- Common genetic problems in the newborn -- Multiple births -- Maternal drug abuse, exposure, and withdrawal -- Care of the extremely low birth weight infant -- Developmentally supportive care -- Temperature control -- Follow-up care of very preterm and very low birth weight infants -- Neonatal transport -- Discharge planning -- Decision making and ethical dilemmas -- Management of neonatal end-of-life care and bereavement follow-up -- Nutrition -- Breastfeeding -- Fluid and electrolyte management -- Hypoglycemia and hyperglycemia -- Abnormalities of serum calcium and magnesium -- Neonatal hyperbilirubinemia -- Necrotizing enterocolitis -- Renal conditions -- Mechanical ventilation -- Blood gas and pulmonary function monitoring -- Apnea -- Transient tachypnea of the newborn -- Respiratory distress syndrome -- Bronchopulmonary dysplasia/chronic lung disease -- Meconium aspiration -- Persistent pulmonary hypertension of the newborn -- Pulmonary hemorrhage -- Pulmonary air leak -- Extracorporeal membrane oxygenation -- Shock -- Cardiac disorders -- Blood products used in the newborns -- Bleeding -- Neonatal thrombosis -- Anemia -- Polycythemia -- Neonatal thrombocytopenia -- Viral infections -- Bacterial and fungal infections -- Congenital toxoplasmosis -- Syphilis -- Tuberculosis -- Lyme disease -- Intracranial hemorrhage -- Perinatal asphyxia and hypoxic-ischemic encephalopathy -- Neonatal seizures -- Neural tube defects -- Orthopaedic problems -- Osteopenia (metabolic bone disease) of prematurity -- Inborn errors of metabolism -- Disorders of sex development -- Surgical emergencies in the newborn -- Skin care -- Retinopathy of prematurity -- Hearing loss in neonatal intensive care unit graduates -- Common neonatal procedures -- Preventing and treating pain and stress among infants in the newborn intensive care unit -- Appendix A: Common neonatal intensive care unit (NICU) medication guidelines -- Appendix B: Effects of maternal drugs on the fetus -- Appendix C: Maternal medications and breastfeeding.
  • Part 1. Lung Development and Maldevelopment -- Development of the Respiratory System -- Developmental Lung Anomalies -- Part 2. Principles of Mechanical Ventilation -- Spontaneous Breathing -- Pulmonary Gas Exchange -- Oxygen Therapy -- Oxygen Toxicity -- Pulmonary Mechanics -- Basic Principles of Mechanical Ventilation -- Classification of Mechanical Ventilation Devices -- Ventilator Parameters -- Respiratory Gas Conditioning and Humidification -- Part 3. Procedures and Techniques -- Clinical Examination -- Neonatal Resuscitation -- Laryngoscopy and Endotracheal Intubation -- Vascular Access -- Tracheostomy -- Part 4. Monitoring the Ventilated Patient -- Continuous Monitoring Techniques -- Pulse Oximetry -- Interpretation of Blood Gases -- Neonatal Pulmonary Graphics -- Radiography -- Transillumination -- Echocardiography -- Bronchoscopy -- Part 5. Non-Invasive Ventilatory Techniques -- Nasal Cannula Therapy -- Continuous Positive Airway Pressure -- Non-invasive Ventilation -- Part 6. Ventilatory Modes and Modalities -- Positive End-Expiratory Pressure -- Intermittent Mandatory Ventilation -- Synchronized Intermittent Mandatory Ventilation -- Assist/Control Ventilation -- Volume-Targeted Ventilation -- Pressure Control Ventilation -- Pressure Support Ventilation -- Proportional Assist Ventilation -- Part 7. High-Frequency Ventilation -- High-Frequency Ventilation: General Concepts -- High-Frequency Jet Ventilation -- High-Frequency Oscillatory Ventilation -- Part 8. Commonly Used Neonatal Ventilators -- VIP Bird Gold Ventilator -- AVEA Ventilator -- Bear Cub 750PSV -- Newport Wave -- Newport e360 -- Dräger Babylog VN500 Infant and Pediatric Ventilator -- SERVO-i Ventilator and Neurally Adjusted Ventilatory Assist (NAVA) -- SLE5000 and SLE4000 Infant Ventilators -- Bunnell Life Pulse High-Frequency Jet Ventilator -- Sensormedics 3100A High-Frequency Oscillatory Ventilator -- Part 9. Adjunctive Therapies -- Hemodynamic Support -- Nutritional Support of the Ventilated Infant -- Surfactant Replacement Therapy -- Pharmacologic Agents -- Automatic Control of Oxygen Delivery -- Sedation and Analgesia -- Inhaled Nitric Oxide Therapy -- Extracorporeal Membrane Oxygenation -- Liquid Ventilation for Neonatal Respiratory Failure -- Part 10. Management of Common Neonatal Respiratory Diseases -- Mechanisms of Respiratory Failure -- Tissue Hypoxia -- Indications for Mechanical Ventilation -- Respiratory Distress Syndrome -- Pneumonia -- Meconium Aspiration Syndrome -- Persistent Pulmonary Hypertension of the Newborn -- Congenital Diaphragmatic Hernia -- Pulmonary Hypoplasia/Agenesis -- Apnea Syndromes -- Weaning and Extubation -- Part 11. Bronchopulmonary Dysplasia -- Etiology and Pathogenesis -- Management -- Long-Term Outcome of Newborns with Bronchopulmonary Dysplasia -- Part 12. Complications Associated With Mechanical Ventilation -- Thoracic Air Leaks -- Patent Ductus Arteriosus -- Neonatal Pulmonary Hemorrhage -- Retinopathy of Prematurity -- Neurologic Complications of Mechanical Ventilation -- Part 13. Other Considerations -- Nursing Care of the Ventilated Infant -- Transport of Ventilated Babies -- Home Ventilation -- Discharge Planning and Follow-Up of the NICU Graduate -- Part 14. Ethical and Legal Considerations -- Initiation of Life Support at the Border of Viability -- Withdrawal of Ventilatory Support -- Medical Liability, Documentation, and Risk Management -- Part 15. Research and the Literature -- Interpreting Medical Literature.
  • The edematous patient : cardiac failure, cirrhosis, and nephrotic syndrome / Robert W. Schrier and David H. Ellison -- The patient with hyponatremia or hypernatremia / Robert W. Schrier and Tomas Berl -- The patient with hypokalemia or hyperkalemia / Catherine L. Kelleher and Stuart L. Linas -- The patient with an acid-base disorder / William D. Kaehny -- The patient with disorders of serum calcium and phosphate / Jeffrey G. Penfield and Robert F. Reilly -- The patient with kidney stones / Amir S.A. Naderi and Robert F. Reilly -- The patient with urinary tract infection / Marilyn E. Levi and L. Barth Reller -- The patient with hematuria, proteinuria, or both, and abnormal findings on urinary microscopy / Sharon G. Adler and Kenneth Fairley -- The patient with glomerulonephritis or vasculitis / Joshua M. Thurman and Alexander Wiseman -- The patient with acute renal failure / Sarah Faubel, Robert E. Cronin, and Charles L. Edelstein -- The patient with chronic kidney disease / Michael Chonchol and David M. Spiegel -- The patient receiving chronic renal replacement with dialysis / David M. Spiegel and Rebecca Moore -- The patient with a kidney transplant / Eric Gibney, Chirag Parikh, and Alkesh Jani -- The patient with kidney disease and hypertension in pregnancy / Phyllis August -- The patient with hypertension / Charles R. Nolan -- Practical guidelines for drug dosing in patients with impaired kidney function / George R. Aronoff and Michael E. Brier.
  • The edematous patient : cardiac failure, cirrhosis, and nephrotic syndrome / Robert W. Schrier and David H. Ellison -- The patient with hyponatremia or hypernatremia / Robert W. Schrier and Tomas Berl -- The patient with hypokalemia or hyperkalemia / Jie Tang and Stuart L. Linas -- The patient with an acid-base disorder / William D. Kaehny -- The patient with disorders of serum calcium and phosphorus / Jeffrey G. Penfield and Robert F. Reilly -- The patient with kidney stones / Robert F. Reilly -- The patient with urinary tract infection / Jessica B. Kendrick, L. Barth Reller, and Marilyn E. Levi -- The patient with hematuria, proteinuria, or both, and abnormal findings on urinary microscopy / Godela Brosnahan -- The patient with glomerular disease or vasculitis / Sarah E. Panzer and Joshua M. Thurman -- The patient with acute kidney injury / Sarah Faubel and Charles L. Edelstein -- The patient with chronic kidney disease / Michel Chonchol and Jessica B. Kendrick -- The patient receiving chronic renal replacement with dialysis / Seth Ferguson and Isaac Teitelbaum -- The patient with a kidney transplant / James Cooper, Lawrence Chan, and Alexander Wiseman -- The patient with kidney disease and hypertension in pregnancy / Phyllis August, Diana I. Jalal, and Judy Blaine -- The patient with hypertension / Seth Ferguson, Charles R. Nolan, and Robert W. Schrier -- Practical guidelines for drug dosing in patients with impaired kidney function / Ali Olyaei and William Bennett.
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    Approach to nutrient deficiency -- Recommendations for healthy young adults -- Recommendations for healthy elderly adults -- Pregnancy and lactation -- Protein and calories: requirements, intake, and assessment -- Vitamins -- Minerals -- Alternative nutritional therapy -- Nutritional support decision making -- Enteral nutritional therapy -- Parenteral nutritional therapy -- Use of diets and dietary components in clinical practice -- Dietary management of diabetes, renal disease, and hyperlipidemia -- Obesity -- Nutritional considerations in chronic wasting diseases (cancer, AIDS).
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  • Prenatal care -- Normal labor -- Obstetric anesthesia -- Puerperium -- Contraception, sterilization, and abortion -- Pregnancy loss and spontaneous abortion -- Ectopic pregnancy -- Preterm labor, premature rupture of membranes, and cervical insufficiency -- Third-trimester bleeding -- Abnormal labor -- Preeclampsia -- Cardiovascular disease and chronic hypertension -- Renal complications -- Respiratory complications -- Hepatobiliary complications -- Gastrointestinal complications -- Endocrine disorders: diabetes -- Endocrine disorders: thyroid, parathyroid, adrenal, and pituitary disease -- Hematologic complications -- Immunologic complications -- Vascular complications -- Thromboembolic disorders -- Infectious complications -- Neurologic complications -- Dermatologic complications -- Substance abuse -- Gynecologic complications -- Surgical problems and trauma -- Genetics, genetic counseling, and genetic risk assessment -- Teratogens and birth defects -- Obstetric ultrasound -- Fetal monitoring and testing -- Fetal growth abnormalities -- Multiple gestations -- Isoimmunization -- Disease of the placenta -- Neonatal resusciatation -- Neonatal complications.
  • Part I. Obstetric care -- Part II. Obstetric complications -- Part III. Maternal complications -- Part IV. Fetal assessment -- Part V. Fetal complications -- Part VI. Neonatal care.
  • Ocular examination techniques and diagnostic tests / Pedram Hamrah and Deborah Pavan-Langston -- Burns and trauma / Deborah Pavan-Langston and Pedram Hamrah -- Eyelids and lacrimal system / Peter A.D. Rubin -- Orbital disorders / Peter A.D. Rubin -- Cornea and external disease / Kathryn Colby and Deborah Pavan-Langston -- Refractive surgery / Dimitri T. Azar -- The crystalline lens and cataract / Dimitri T. Azar and Jose J. de la Cruz Napoli -- Retina and vitreous / Peter Reed Pavan, Andrew Burrows, and Deborah Pavan-Langston -- Uveal tract: iris, ciliary body, and choroid / Deborah Pavan-Langston, Anat Galor, and Victor L. Perez -- Glaucoma / Deborah Pavan-Langston, Stacey C. Brauner, and Cynthia L. Grosskreutz -- Pediatric ophthalmology / Gena Heidary and Melanie Kazlas -- Extraocular muscles, strabismus, and nystagmus / Deborah Pavan-Langston and Nathalie Azar -- Neuro-ophthalmology: visual fields, optic nerve, and pupil / Shirley H. Wray -- Refractive error, clinical optics, and contact lenses / Jill E. Beyer and Deborah Pavan-Langston -- Ocular manifestations of systemic disease / Deborah Pavan-Langston -- Ocular toxicity of systemic drugs / Deborah Pavan-Langston.
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    Classifications of fractures, dislocations, and sports-related injuries -- Musculoskeletal diseases and related terms -- Imaging techniques -- Orthopaedic tests, signs, and maneuvers -- Laboratory evaluations -- Casts, splints, dressings, and traction -- Prosthetics and orthotics -- Anatomy and orthopaedic surgery -- The spine -- The hand and wrist -- The foot and ankle -- Musculoskeletal research.
  • In its 38th year, A Manual of Orthopaedic Terminology has been a companion reference for anyone who needs the most up-to-date terms, acronyms, and codes terms relating to clinical orthopaedics and research. Portable and easily accessible, this authoritative compilation categorizes and cross-references terms to enable those unfamiliar with orthopaedics to locate a term in its proper context. Unlike a traditional A-Z dictionary format, terms are organized by topic-facilitating faster search results with related terms appearing on the same or immediately adjacent page.
  • Temporal bone dissection training is paramount to the surgical education of any otolaryngologist and a special rite of passage for those who wish to focus their practice on otology. The complexity of temporal bone anatomy, which is exposed in a stepwise fashion during dissection, holds a particular fascination for surgeons at all levels, while mastery of the microsurgical anatomy remains the most basic attribute defining surgical competence and skills. In spite of the recent progress in surgical simulation, the cadaver bone remains the gold standard and provides an indispensable platform for otological training. The Manual of Otologic Surgery takes the reader step-by-step through routine temporal bone surgeries while maximizing the use of the cadaver tissue. In an effort to improve visual realism, the book provides high-resolution photographs and anatomically accurate illustrations to allow the reader to better appreciate the three-dimensional relationship of the internal constructs of the temporal bone. Special emphasis is placed on describing the latest techniques for cochlear implantation and active middle ear implants. The book is further enhanced by additional links to edited videos of surgical cases and will therefore serve as a valuable reference guide to otologic surgeons of all experience levels.
  • An ever growing population of patients are affected by cardiac disease. Most of these diseases are chronic in nature and require long term outpatient follow up. Subsequently, outpatient providers are finding themselves responsible for an increasing number of patients with cardiovascular issues. Appropriate diagnosis and management of cardiac disease is essential to providing high quality care in an efficient manner. There is a wide spectrum of providers involved in the care of these patients, many of which are not cardiologists. The Manual of Outpatient Cardiology is written in a practical, didactic format designed to deliver point-of-care information to practitioners of cardiology and assist non-cardiologists with the efficient management of cardiac disease. Highly illustrated with schematics and useful clinical figures, this book is an essential reference to all outpatient cardiology procedures.
  • Part 1. Approach to the Specimen -- Evaluation of the First-Trimester Products of Conception -- Evaluation of the Second-Trimester Products of Conception -- Macroscopic Evaluation of the Second and Third Trimester Placenta -- Microscopic Evaluation of the Second- and Third-Trimester Placenta -- Part 2. Development and Normal Histology -- Early Placental Development -- Chorionic Villi: Histology and Villous Development -- Overview and Microscopic Survey of the Placenta -- Extravillous Trophoblast, Trophoblastic Invasion, and Fibrinoid -- Part 3. Multiple Gestation -- Multiple Gestation: General Aspects -- Multiple Gestation: Twin Variants and Related Conditions -- Part 4. Abnormalities of the Placenta -- Abortion and the Placenta in Chromosomal Anomalies -- Postpartum Hemorrhage, Subinvolution of the Placental Site, and Placenta Accreta -- Placental Shape Aberrations -- Pathology of the Fetal Membranes -- Part 5. Disease Processes and the Placenta -- Infectious Diseases -- Maternal Diseases Complicating Pregnancy -- Placental Malperfusion -- Miscellaneous Placental Lesions -- Placental Abnormalities in Fetal Conditions -- Fetal Thrombotic Vasculopathy -- Part 6. Neoplasms and Gestational Trophoblast Disease -- Neoplasms -- Hydatidiform Moles -- Choriocarcinoma -- Lesions of Extravillous Trophoblast -- Part 7. Legal Considerations and New Directions -- Legal Considerations -- New Directions: What is New in Placental Studies?
  • Psychological aspects -- Anatomy and physiology -- Clinical pharmacology -- Techniques and procedures -- Regional anesthesia techniques -- Medical conditions influencing anesthetic management -- Postoperative care and pain management -- Neurosurgery and invasive neuroradiology -- Opthalmology -- Otorhinolaryngology -- Dental surgery -- Plastic and reconstructive surgery -- General and thoracoabdominal surgery -- Cardiovascular surgery and cardiologic procedures -- Orthopedic surgery -- Urologic investigation and surgery -- Trauma, including acute burns and scalds -- Anesthesia in remote locations.
  • 2011 ClinicalKey
    Chapter 1. Classification and Diagnosis of Anemia in Children -- Chapter 2. Anemia During the Neonatal Period -- Chapter 3. Iron-Deficiency Anemia -- Chapter 4. Megaloblastic Anemia -- Chapter 5. Hematologic Manifestations of Systemic Illness -- Chapter 6. Bone Marrow Failure -- Chapter 7. Red Cell Membrane and Enzyme Defects -- Chapter 8. Hemoglobinopathies -- Chapter 9. Extracorpuscular Hemolytic Anemia -- Chapter 10. Polycythemia -- Chapter 11. Disorders of White Blood Cells -- Chapter 12. Disorders of Platelets -- Chapter 13. Hemostatic Disorders -- Chapter 14. Thrombotic Disorders -- Chapter 15. Lymphadenopathy and Splenomegaly -- Chapter 16. Lymphoproliferative Disorders, Myelodysplastic Syndromes and Myeloproliferative Disorders -- Chapter 17. Leukemias -- Chapter 18. Histiocytosis Syndromes -- Chapter 19. Hodgkin Lymphoma -- Chapter 20. Non-Hodgkin Lymphoma -- Chapter 21. Central Nervous System Malignancies -- Chapter 22. Neuroblastoma -- Chapter 23. Renal Tumors -- Chapter 24. Rhabdomyosarcoma and Other Soft-Tissue Sarcomas -- Chapter 25. Malignant Bone Tumors -- Chapter 26. Retinoblastoma -- Chapter 27. Germ Cell Tumors -- Chapter 28. Hepatic Tumors -- Chapter 29. Hematopoietic Stem Cell Transplantation -- Chapter 30. Management of Oncologic Emergencies -- Chapter 31. Supportive Care of Patients with Cancer -- Chapter 32. Evaluation, Investigations and Management of Late Effects of Childhood Cancer -- Chapter 33. Psychosocial Aspects of Cancer for Children and their Families.
  • This manual is designed to meet the everyday needs of the wide range of medical professionals across the globe who play a role in the treatment of children referred because of renal disease. It is an easy-to-use, portable guide that will assist pediatricians, residents, and trainees in making prompt and appropriate first-level management decisions. It will also prove invaluable for adult nephrologists who are responsible for the care of children in many developing areas of the world, and will serve as a teaching guide for experts when training non-subspecialists. Individual sections are devoted to the evaluation of renal disease; fluid, electrolyte, and acid-base disorders; glomerular diseases; tubular disorders; congenital, inherited, and urological disorders; consequences of renal disease; and miscellaneous topics. The text is in a bulleted format with tables and algorithms wherever possible, making it straightforward and easy to read. An appendix includes further important information such as normal values, drug dosages, dosage adjustment in renal failure, drug nephrotoxicity, and dietary recommendations. The complexities of pediatric nephrology like pathogenesis, intricate physiological aspects, and details of advanced management are deliberately avoided since these issues typically arise during tertiary care at a referral center. If you are searching for a practical, comprehensive guide on pediatric nephrology that will meet the first-line needs of all practitioners, whether in developed or developing countries, this manual will be ideal.
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    Synopsis of adult cardiac surgical disease -- Diagnostic techniques in cardiac surgery -- Preoperative considerations and risk assessment -- Cardiac anesthesia -- Cardiopulmonary bypass -- Myocardial protection -- Admission to the ICU and monitoring techniques -- Early postoperative care -- Mediastinal bleeding -- Respiratory management -- Cardiovascular management -- Fluid management, renal and metabolic problems -- Post-ICU care and other complications.
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  • This manual of spine surgery has become necessary as a consequence of the rapid expansion of instrumented spine surgery using different minimally invasive and non-fusion techniques. To do justice to this development, the manual aims to present the different techniques to spinal surgeons (orthopaedic and neurosurgeons) in a clear and instructive way using detailed illustrations. The description of different open, less invasive or minimally invasive techniques will provide the spinal surgeon with useful guidelines for their use. The success of any spinal operation depends on good definition of the indications, consideration of the contraindications, technical and organisational factors, good operating technique and correct preoperative preparation and positioning of the patient. These points are presented in this book as clearly as possible and are illustrated with detailed high quality artwork.
  • Dr. Lester's Manual of Surgical Pathology, 3rd Edition offers complete, practical guidance on the evaluation of the surgical pathology specimen, from its arrival in the department to preparation of the final report. Inside, you'll find step-by-step instructions on specimen processing, tissue handling, gross dissection technique, histological examination, application of special stains, development of a differential diagnosis, and more. This thoroughly revised New Edition integrates cutting-edge procedures well as the latest staging and classification information. Coverage of the latest standards and procedures for the laboratory and handling of surgical pathology specimens are valuable assets to pathologists, pathology assistants, and anyone working in a pathology laboratory. Plus, with Expert Consult functionality, you'll have easy access to the full text online as well as all of the books illustrations and links to Medline. Features more than 150 tables that examine the interpretation of histochemical stains, immunohistochemical studies, electron microscopy findings, cytogenetic changes, and much more. Presents a user-friendly design, concise paragraphs, numbered lists, and bulleted material throughout the text that makes information easy to find. Offers detailed instructions on the dissection, description, and sampling of specimens. Includes useful guidance on operating room consultations, safety, microscope use, and error prevention. Explains the application of pathology reports to patient management. Discusses how to avoid frequent errors and pitfalls in pathology specimen processing.
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    The morphology and development of the atrial chambers, with particular regard to atrial fibrillation -- Pathophysiology of atrial fibrillation -- Genetics of atrial fibrillation -- Pharmacological management of atrial fibrillation -- Electrophysiological basis of atrial fibrillation -- Pulmonary and thoracic vein sources: the focal theory of atrial fibrillation -- Surgical treatment of atrial fibrillation: a retrospection -- The maze procedure: past, present, and future -- The radial procedure for atrial fibrillation: theoretical basis and clinical application -- The mini-maze operation -- Alternative energy sources for the surgical treatment of atrial fibrillation -- Radiofrequency modified maze surgery for chronic atrial fibrillation and concomitant cardiac surgery: Zwolle experience -- Bipolar radiofrequency ablation of atrial fibrillation -- Surgical ablation therapy using microwave energy: endo- and epicardial approach -- Epicardial ablation in the treatment of atrial fibrillation -- Surgical treatment of atrial fibrillation: the Japanese experience -- Minimally invasive surgical approach to treat atrial fibrillation -- Percutaneous treatment of atrial fibrillation -- Surgical ablation of arrhythmias associated with congenital cardiopathies -- Perioperative complications during surgical treatment of atrial fibrillation: tips and pitfalls.
  • Drills -- Microscope -- Preparation and Planning -- Identify following structures prior to the surgical exercises -- Mastoid -- Antrostomy -- Mastoidectomy -- Identification of the semicircular canals -- Posterior tympanotomy -- Identification of the facial nerve in its mastoidal portion -- Cochleostomy -- Endolymphatic sac surgery -- Epitympanotomy -- Open mastoid cavity -- Facial nerve decompression -- Labyrinthectomy -- Translabyrinthine approach to the internal auditory canal -- Transtemporal approach to the internal auditory canal -- Perforation of the tympanic membrane -- Ossicular chain reconstruction -- PORP -- TORP -- Stapes surgery -- Malleovestibulopexy.
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    v. 1. Basic protection requirements / C.B. Braestrup, K.J. Vikterlöf, 1974 -- v. 2. Unsealed sources / D. Frost, H. Jammet, 1975 -- v. 3. X-ray diagnosis / B.E. Keane, K.B. Tikhonov, 1975 -- v. 4. Radiation protection in dentistry / K. Koren, A.H. Wuehrmann, 1977 -- v. 5. Personnel monitoring services / W. Minder, S.B. Osborn, 1980.
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  • "Vitamin A plays a key role among the vitamins essential for healthy growth and development. Vitamin A deficiency disorders (VADD) are therefore an important part of general malnutrition that in the majority of cases leads to failure to thrive and underweight. Moreover, apart from adverse effects on health and survival in general, VADD can also lead to blindness, called xerophthalmia, and are also frequently accompanied by various infections. Last but not least, it has become evident that even mild degrees of VAD (and all other forms of nutritional deficiencies) have important adverse implications for health and are thus much more widespread than previously assumed. This publication systematically covers detailed and up-to-date information on every relevant aspect of VADD, with particular emphasis on providing an outline of their setting, nature, and significance. In addition to cutting-edge scientific information, the latest available data on the global occurrence of VAD from the World Health Organization is also included."--Publisher website.
  • The MAP kinase signaling cascades : A system of hundreds of components regulates a diverse array of physiological functions -- Determination of ERK activity: Anti-phospho-ERK antibodies and in vitro phosphorylation -- Activation of SAPK/JNKs in vitro -- Activation of p38 and determination of its activity -- Activity assays for extracellular signal-regulated kinase 5 -- Use of inhibitors in the study of MAP kinases -- MAP kinase activation by receptor tyrosine kinases : in control of cell migration -- Activation of ras and rho GTPases and MAP kinases by G-protein-coupled receptors -- Regulation of MAP kinase signaling by calcium -- Identification of novel substrates of MAP kinase cascades using bioengineered kinases that uniquely utilize analogs of ATP to phosphorylate substrates -- ERK-MAP kinase signaling in the cytoplasm -- Lentiviral vectors to study the differential function of ERK1 and ERK2 MAP kinases -- Structural studies of MAP kinase cascade components -- Analysis of MAP kinases by hydrogen exchange mass spectrometry -- A "Molecular evolution" approach for isolation of intrinsically active (MEK-independent) MAP kinases -- Reconstitution of the nuclear transport of the MAP kinase ERK2 -- Localization and trafficking of fluorescently tagged ERK1 and ERK2 -- Studying the regulation of MAP kinase by MAP kinase phosphatases in vitro and in cell systems -- Proteomic analysis of scaffold proteins in the ERK cascade -- Analysis of ERKs' dimerization by electrophoresis -- MAP kinase: SUMO pathway interactions -- Computational modelling of kinase signalling cascades -- Analysis of mitogen-activated protein kinase activity in yeast -- Detection of RTK pathway activation in drosophila using anti-dpERK immunofluorescence staining -- Studying MAP kinase pathways during early development of xenopus laevis -- Deciphering signaling pathways in vivo : The ras/raf/MEK/ERK cascade -- Mutational and functional analysis in human ras/MAP kinase genetic syndromes -- Implication of the ERK pathway on the post-transcriptional regulation of VEGF mRNA stability -- Studies on MAP kinase signaling in the immune system -- Methods to study MAP kinase signalling in the central nervous system -- MAP kinase regulation of the mitotic spindle checkpoint -- Using high-content microscopy to study gonadotrophin-releasing hormone regulation of ERK.
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  • In response to persistent donor organ shortages, organs from marginal donors, such as expanded criteria donors (ECD) and donation after cardiac death (DCD) donors, are now accepted and have been successfully transplanted, reducing the waiting times for transplantation. Especially in Japan, transplantation of DCD kidneys has a relatively long history because of the difficulty or lack of national consensus in accepting brain death, which has made it possible to accumulate considerable clinical experience. Thus, the current organ shortage has stimulated interest in the use of marginal donors for transplantation. This book, prepared by distinguished authorities in their fields, is intended for clinicians and researchers. It highlights the use of marginal donors as a comparatively novel source of transplantation organs and provides a thorough overview of marginal donors from their historical origins to recent clinical applications, including the state-of-the-art science of organ/donor management, procurement, and preservation. Also provided is valuable information on ABO-incompatible donors which extend the availability of donor sources. Each chapter offers an individual analysis of the optimal requirements for the safe management and preservation of organs, including the heart, lung, liver, kidney, pancreas, and pancreatic islets.
  • Cannabis and natural cannabis medicines / Robert C. Clarke and David P. Watson -- Chemistry and analysis of phytocannabinoids and other cannabis constituents / Rudolf Brenneisen -- Chemical fingerprinting of cannabis as a means of source identification / Mahmoud A. ElSohly, Donald F. Stanford, and Timothy P. Murphy -- Marijuana smoke condensate: chemistry and pharmacology / Hala N. ElSohly and Mahmoud A. ElSohly -- Pharmacology of cannabinoids / Lionel P. Raymon and H. Chip Walls -- The endocannabinoid system and the therapeutic potential of cannabinoids / Billy R. Martin -- Immunoassays for the detection of cannabis abuse: technologies, development strategies, and multilevel applications / Jane S-C. Tsai -- Mass spectrometric methods for determination of cannabinoid physiological specimens / Rodger L. Foltz -- Human cannabinoid pharmacokinetics and interpretation of cannabinoid concentrations in biological fluids and tissues / Marilyn A. Huestis and Michael L. Smith -- Medical and health consequences of marijuana / Jag H. Khalsa -- Effects of marijuana on the lung and immune defenses / Donald P. Tashkin and Michael D. Roth -- Marijuana and driving impairment / Barry K. Logan -- Postmortem considerations / Steven B. Karch -- Cannabinoid effects on biopsychological, neuropsychiatric and neurological processes / Richard E. Musty.
  • Marine microbiology 2001
    ScienceDirect
  • Marine fisheries by-products as potential nutraceuticals: an overview / Se-Kwon Kim, Eresha Mendis, and Fereidoon Shahidi -- Omega-3 oils: sources, applications, and health effects / Fereidoon Shahidi -- Omega-3s and their impact on brain health / Genevieve Young and Julie Conquer -- Omega-3 fatty acids in the treatment of neurodegenerative diseases through anti-inflammation and neuroprotection: a review of studies in animal models / Cai Song -- Microencapsulation of marine lipids as a vehicle for functional food delivery / Yulai Jin ... [et al.] -- Chitin and chitosan / Rosalee S. Rasmussen and Michael T. Morrissey -- Production of bioactive chitosan oligosaccharides and their potential use as nutraceuticals / Se-Kwon Kim, Niranjan Rajapakse, and Fereidoon Shahidi -- Glucosamine production and health benefits / Jaroslav A. Kralovec and Colin J. Barrow -- Functional and bioactive peptides from hydrolyzed aquatic food proteins / Hordur G. Kristinsson -- Marine-derived protein hydrolysates, their biological activities and potential as functional food ingredients: ace-inhibitory peptides derived from bonito / Hiroyuki Fujita and Masashi Yoshikawa -- Marine algal constituents / Yvonne V. Yuan -- Beneficial health effects of seaweed carotenoid, fucoxanthin / Kazuo Miyashita and Masashi Hosokawa -- The production and health benefits of astaxanthin / Miguel Olaizola -- Marine algae and polysaccharides with therapeutic applications / J. Helen Fitton, Mohammad R. Irhimeh, and Jane Teas -- Nutraceuticals and functional foods from marine microbes: an introduction to a diverse group of natural products isolated from marine macroalgae, microalgae, bacteria, fungi, and cyanobacteria / Adam M. Burja and Helia Radianingtyas -- Shark cartilage: potential for therapeutic application for cancer--review article / Kenji Sato ... [et al.] -- Calcium from fish bone and other marine resources / Won-Kyo Jung, Fereidoon Shahidi, and Se-Kwon Kim -- Immunoenhancing preparations of marine origin / Jaroslav A. Kralovec and Colin J. Barrow.
  • "A fundamental sourcebook for the care of critically ill patients. This edition continues the original intent to provide a "generic textbook" that presents fundamental concepts and patient care practices that can be used in any adult intensive care unit, regardless of the specialty focus of the unit"--Provided by publisher.
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    Emerging threats to the public's health: the need for social change -- Marketing social change-a challenge for the public health practitioner -- Marketing social change-an opportunity for the public health practitioner -- Emerging threats to the survival of public health -- Marketing public health-a challenge for the public health practitioner -- Marketing public health: an opportunity for the public health practitioner -- Urunana: radio health communication: a case study from Rwanda -- Marketing public health as an institution: a case study -- Applying marketing principles to public health -- The planning process -- Formative research -- Framing and delivering the message: crafting communication strategies --Translating strategy into tactics -- Working with partners, allies, coalitions, and intermediaries -- Promotional materials and activities -- Monitoring and refining implementation: process evaluation tools -- Outcome evaluation issues and designs --Overview of common theories and marketing research methods.
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    "A history of botanical remedies, hypnotic suggestion, water cures, and other alternative medicine in nineteenth-century America"--Dust jacket.
  • "One of the strengths of Marriott's Practical Electrocardiography through its more than 50-year history has been its lucid foundation for understanding the basis for ECG interpretation. Again, in this revision, we have attempted to retain the best of the Marriott tradition--emphasis on the concepts required for everyday ECG interpretation and the simplicities, rather than complexities, of the ECG recordings. During preparation of the 9th and 10th editions, Tobin Lim coauthored many of the 11th edition chapters and served as the primary developer of the digital content associated with that edition. Tobin Lim's input continues into this 12th edition, and David Strauss has led even further into the electronic-based interactive learning experiences. More than 30 of the figures that evolved through previous editions have now been converted through the creative expertise of Mark Flanders into animated movies accessed via QR codes imbedded in the book. David has also collaborated with electrocardiographic educators who are especially skilled in e-based education to add interactive video content to many of the 12th edition chapters. Each of the now 24 chapters is divided (as indicated in the table of contents) into discrete, compact "learning units." Each learning unit begins on a new page to provide blank space for the reader's notes. The purpose of the learning units is to make this book easier to use by allowing the reader to be selective regarding the material to be considered at a particular time. Because the modern student of electrocardiography is primarily oriented to a visual perspective, we have typically begun each page with an illustration"--Provided by publisher.
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    v. 1. Reproductive cycles of vertebrates.
  • Martindale, The Complete drug reference
    Truven, Search Martindale via the main Micromedex search screen.
  • Evaluting efficacy of barrier creams: in vitro and in vivo models -- Light-induced dermal toxicity: effects on cellular and molecular levels -- Failure of standard test batteries for detection of genotoxic activity of some chemicals used in dermatological and cosmetic products -- Exogenous ochronosis: update -- Diagnostic patch test: science and art -- Irritant and allergic contact dermatitis treatment -- Factors affecting children's susceptibility to chemicals -- Utilization of irritation data in local lymph node assay -- Air bag injuries -- Cigarette smoking and skin -- Chemical analysis of tattoo pigments cleaved by laser light -- Dermatotoxicology of specialized epithelia: adapting cutaneous test methods to assess topical effects on vulva -- Anti-irritants: myth or reality? overview -- Evaluating mechanical and chemical irritation using the behind-the-knee tests: review -- Need for more sensitive tools as we reach limits of our ability to detect differences in skin effects from mild products -- Drug patch testing in systemic cutaneous drug allergy -- Hormesis and dermatology -- Diagnosis of drug hypersensitivity in vitro -- Immunologic patterns in allergic and irritant contact dermatitis: similarities -- Water decontamination of chemical skin and eye splashes: critical review -- Chemical substances and contact allergy: 244 substances ranked according to allergenic potency -- Use of modified forearm controlled application test to evaluate skin irritation of lotion formulations -- Hair in toxicology -- Popliteal lymph node assay -- Pigmentation changes resulting from arsenic exposure -- Textiles and human skin, microclimate, cutaneous reactions: overview -- In vivo human transfer of topical bioactive drugs among individuals: estradiol -- Is there evidence that geraniol causes allergic contact dermatitis? -- Operational definition of a causative contact allergen-study with six fragrance allergens -- Sodium lauryl sulfate-induced irritation in human faces: regional- and age-related differences -- Classification of irritant contact dermatitis -- In vitro skin irritation testing on SkinEthic[tm]-reconstituted human epidermis: reproducibility for fifty chemicals tested with two protocols -- Identifying source of textile-dye allergic contact dermatitis: guidelines -- Functional map and age-related differences in human faces: nonimmunologic contact urticaria induced by hexyl nicotinate -- Is contact allergy lifelong in humans? an overview of patch-test follow-ups -- Irritants in combination with synergistic or additive effect on skin response overview of tandem irritation studies -- Allergic contact dermatitis from iodine preparations: a conundrum? -- Human skin buffering capacity: oveview. Pesticide percutaneous absorption and decontamination -- Tape stripping method versus stratum corneum -- Parameters influencing stratum corneum removal by tape stripping -- Quantification of stratum corneum removed by tape stripping -- Isolated perfused porcine skin flap -- Physiologically based pharmacokinetic modeling -- Methods for in vitro skin metabolism studies -- Predicitive toxicology methods for transdermal delivery systems -- Animal, human, and in vitro test methods for predicting skin irritation -- Kawaki method for testing irritation -- Analysis of structural change in intercellular lipids of humam stratum corneum induced by surfactants: electron paramagnetic resonance (EPR) study -- Water and saline compresses in treatment of irritant contact dermatitis: literature review -- Reaction of skin blood vessels to successive insults on normal and irritated human skin -- Specificity of retinoid-induced irritation and its role in clinical efficacy -- Topical corticosteroids in the treatment of irritant dermatitis: do they work? -- Tests for sensitive skin -- Test methods for allergic contact dermatitis in animals -- Test methods for allergic contact dermatitis in humans -- Allergic contact dermatitis: elicitation thresholds of potent allergens in humans -- Allergic contact dermatitis to topical anesthetics: a cross-sensitization phenomenon -- Contact urticaria and anaphylaxis to chlorhexidine: overview -- Immunoadjuvants in prospective testing for contact allergens -- Local lymph node assay -- Iontophresis in humans: regional variations in skin barrier function and cutaneous irritation -- Contact urticaria and contact urticaria syndrome (immediate contact reactions) -- In vitro approaches to assessment of skin irritation and phototoxicity of topically applied materials -- Photoirritation (phototoxicity) testing in humans -- Measuring and quantifying ultraviolet radiation exposures -- Determination of subclinical changes of barrier function -- Assessing validity of alternative methods for toxicity testing: role and activities of ECVAM -- Animal models of contact urticaria -- Diagnostic tests in dermatology: patch and photopatch testing and contact urticaria -- Cosmetic reactions -- Decreasing allergic contact dermatitis frequency through dermatotoxicologic- and epidemiologic-based intervention? -- Cutaneous corticosteroid-induced glaucoma -- Pharmacogenetics and dermatology -- Ethnic differences in skin properties: objective data -- Occlusion and barrier function -- Anatomical factors affecting barrier function -- Percutaneous penetration enhancers: overview -- Percutaneous absorption of complex chemical mixtures -- Percutaneous absorption: short-term exposure, lag time, multiple exposures, model variations, and absorption from clothing -- Percutaneous absorption: 7 roles of lipids -- Chemical partitioning into powdered human stratum corneum: a useful in vitro model for studying interactions of chemicals and human skin -- Sensitive skin -- Transdermal drug delivery system: an overview -- Transdermal drug delivery system: an overview -- Iontophoresis: from historical perspective to its place in modern medicine -- Irritant dermatitis: clinical heterogeneity and contributing factors -- Systemic contact dermatitis -- Allergic contact dermatitis -- Mechanisms in irritant and allergic contact dermatitis -- Occupational allergic contact dermatitis: rational work-up -- Systemic toxicity -- Concepts in molecular dermatotoxicology -- Molecular basis of allergic contact dermatitis -- Photoirritation (phototoxicity, phototoxic dermatitis) -- Permeability of skin to metal compounds, with focus on nickel and copper -- Chemically induced scleroderma -- Chemical agents that cause depigmentation -- Carcinogenesis: current trends in skin cancer research -- Retinoids and mechanisms of their toxicity -- Mechanisms in cutaneous drug hypersensitivity reactions -- Drug-induced ocular phototoxicity -- Water: is it an irritant? -- Sodium lauryl sulfate -- Factors influencing applied amounts of topical preparations -- Barrier creams -- OECD guidelines for testing of chemicals -- Methods for in vitro percutaneous absorption -- Percutaneous absorption of hazardous substances from soil and water --
  • Cancer symptoms and side effects of treatment -- Cancer pain -- Cancer-related fatigue -- Palliative care: end-of-life symptoms -- Supportive care in elderly cancer patients -- Supportive care in pediatric oncology -- Quality-of-life assessment: the challenge of incorporating quality-of-life and patient-reported outcomes into investigative trials and clinical practice -- Cardiac toxicities of cancer therapies: challenges for patients and survivors of cancer -- Malignant pericardial effusion and cardiac tamponade (cardiac and pericardial symptoms) -- The vena cava syndrome -- Pulmonary toxicity of therapy -- Management of respiratory symptoms in people with cancer -- Endocrine and metabolic symptoms of cancer and its treatment -- Sexual problems in patients with cancer -- Sterility, infertility, and teratogenicity -- Menopause symptoms -- Preserving cardiac health in the breast cancer patient treated with anthracyclines -- Thrombosis and bleeding in cancer patients -- Lymphedema care -- Infections and cancer -- Cancer cachexia and anorexia -- Xerostomia and dental problems in the head and neck radiation patient -- Dysphagia, reflux, and hiccups -- Nausea and vomiting -- Mucositis (oral and gastrointestinal) -- Diarrhea, constipation, and obstruction in cancer management -- Ascites -- Hepatotoxicity and hepatic dysfunction -- Urological symptoms and side effects of treatment -- Gynecological symptoms -- Central nervous system symptoms: headache, seizures, encephalopathy, and memory impairment -- Neuromuscular disease and spinal cord compression -- Eye symptoms and toxicities of systemic chemotherapy -- Extravasation -- Dermatologic toxicities -- Chemotherapy-induced alopecia: overview and methodology for characterizing hair changes and regrowth -- Rehabilitation in cancer -- Oral health and survivorship: late effects of cancer and cancer therapy -- Survivorship: psychosocial, physical issues, and insomnia -- Spiritual issues in supportive cancer care.
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    The great pandemic of 1918 -- The Asian flu pandemic of 1957 -- The Hong Kong flu pandemic of 1968.
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    ScienceDirect
  • Imaging mass spectrometry : viewing the future / Sarah A. Schwartz and Richard M. Caprioli -- A mass spectrometry primer for mass spectrometry imaging / Stanislav S. Rubakhin and Jonathan V. Sweedler -- Imaging of metals, metalloids, and non-metals by laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) in biological tissues / J. Sabine Becker and J. Susanne Becker -- Lipid detection, identification, and imaging single cells with SIMS / Michael L. Heien ... [et al.] -- The application and potential of ion mobility mass spectrometry in imaging MS with a focus on lipids / Amina S. Woods and Shelley N. Jackson -- Quantitative imaging of chemical composition in single cells by secondary ion mass spectrometry : cisplatin affects calcium stores in renal epithelial cells / Subhash Chandra -- Imaging MALDI mass spectrometry of sphingolipids using an oscillating capillary nebulizer matrix application system / Yanfeng Chen ... [et al.] -- Mapping pharmaceuticals in rat brain sections using MALDI imaging mass spectrometry / Yunsheng Hsieh, Fangbiao Li, and Walter A. Korfmacher -- Laser ablation electrospray ionization for atmospheric pressure molecular imaging mass spectrometry / Peter Nemes and Akos Vertes -- Matrix-assisted laser desorption/ionization and nanoparticle-based imaging mass spectrometry for small metabolites : a practical protocol / Yuki Sugiura and Mitsutoshi Setou -- Cellular imaging using matrix-enhanced and metal-assisted SIMS / A.F. Maarten Altelaar and Sander R. Piersma -- Tandem mass spectrometric methods for phospholipid analysis from brain tissue / Timothy J. Garrett and Richard A. Yost -- Chemical imaging with desorption electrospray ionization mass spectrometry / Vilmos Kertesz and Gary J. Van Berkel -- Mass spectrometry imaging of small molecules using matrix-enhanced surface-assisted laser desorption/ionization mass spectrometry (ME-SALDI-MS) / Qiang Liu, Yongsheng Xiao, and Lin He -- Preparation of single cells for imaging mass spectrometry / Elena S.F. Berman, Susan L. Fortson, and Kristen S. Kulp -- Applying imaging ToF-SIMS and PCA in differentiation of tissue types / Ligang Wu, James S. Felton, and Kuang Jen J. Wu -- Direct molecular analysis of whole-body animal tissue sections by MALDI imaging mass spectrometry / Michelle L. Reyzer ... [et al.] -- MALDI direct analysis and imaging of frozen versus FFPE tissues : what strategy for which sample? / Maxence Wisztorski ... [et al.] -- On tissue protein identification improvement by N-terminal peptide derivatization / Julien Franck ... [et al.] -- Specific MALDI-MSI : TAG-MASS / Jonathan Stauber ... [et al.] -- Structurally selective imaging mass spectrometry by imaging ion mobility-mass spectrometry / John A. McLean, Larissa S. Fenn, and Jeffrey R. Enders -- Tutorial : multivariate statistical treatment of imaging data for clinical biomarker discovery / Sören-Oliver Deininger, Michael Becker, and Detlev Suckau -- Applications of MALDI-MSI to pharmaceutical research / Brendan Prideaux, Dieter Staab, and Markus Stoeckli -- Tissue preparation for the in situ MALDI MS imaging of proteins, lipids, and small molecules at cellular resolution / Nathalie Y.R. Agar ... [et al.] -- Imaging of similar mass neuropeptides in neuronal tissue by enhanced resolution MALDI MS with an ion trap-Orbitrap hybrid instrument / Peter D.E.M. Verhaert ... [et al.] -- Mass spectrometric imaging of neuropeptides in decapod crustacean neuronal tissues / Ruibing Chen ... [et al.] -- Mass spectrometry imaging using the stretched sample approach / Tyler A. Zimmerman, Stanislav S. Rubakhin, and Jonathan V. Sweedler.
  • Generation and analysis of multidimensional protein identification technology datasets / Selene K. Swanson, Laurence Florens, and Michael P. Washburn -- Quantitative peptide and protein profiling by mass spectrometry / Alexander Schmidt, Birgit Bisle, and Thomas Kislinger -- Label-free relative quantitation of prokaryotic proteomes using the accurate mass and time tag approach / Kim K. Hixson -- Classical proteomics: two-dimensional electrophoresis/MALDI mass spectrometry / Ursula Zimny-Arndt ... [et al.] -- The use of difference in-gel electrophoresis for quantitation of protein expression / Rajat Sapra -- Liquid-chromatography-mass spectrometry of thylakoid membrane proteins / Christian G. Huber ... [et al.] -- High accuracy mass spectrometry in large-scale analysis of protein phosphorylation / Jesper V. Olsen and Boris Macek -- Manual validation of peptide sequence and sites of tyrosine phosphorylation from MS/MS spectra / Amy M. Nichols and Forest M. White -- Assigning glycosylation sites and microheterogeneities in glycoproteins by liquid chromatography/tandem mass spectrometry / Yehia Mechref, Milan Madera, and Milos V. Novotny -- Structure analysis of N -glycoproteins / Stefanie Henning, Jasna Peter-Katalinicʹ, and Gottfried Pohlentz -- Capillary zone electrophoresis-mass spectrometry for the characterization of isoforms of intact glycoproteins / Christian Neusüss, and Matthias Pelzing -- Top-down proteomics on a high-field fourier transform ion cyclotron resonance mass spectrometer / Séverine A. Ouvry-Patat ... [et al.] -- Capillary isoelectric focusing/reversed phase liquid chromatography/mass spectrometry / Cheng S. Lee and Brian M. Balgley -- Integrating accelerated tryptic digestion into proteomics workflows / Gordon W. Slysz and David C. Schriemer -- Hydrogen/deuterium exchange mass spectrometry / Xuguang Yan and Claudia S. Maier -- Mass spectrometry detection and characterization of noncovalent protein complexes / Sheng Yin and Joseph A. Loos -- Chemical cross-linking for protein-protein interaction studies / Xiaoting Tang and James E. Bruce -- Tissue analysis with high-resolution imaging mass spectrometry / A.F. Maarten Altelaar and Ron M.A. Heeren -- Proteomic global profiling for cancer biomarker discovery / Vitor Faca, Hong Wang, and Samir Hanash -- Analysis of protein glycosylation and phosphorylation using liquid phase separation, protein microarray technology, and mass spectrometry / Jia Zhao ... [et al.] -- Transthyretin mass determination for detection of transthyretin familial amyloid / John F. O'Brien and H. Robert Bergen III -- Characterization of microorganisms by MALDI mass spectrometry / Catherine E. Petersen, Nancy B. Valentine, and Karen L. Wahl -- Mass spectrometric characterization of neuropeptides / Stephanie S. DeKeyser, James A. Dowell, and Lingjun Li -- Peptide and protein ion/ion reactions in electrodynamic ion traps: tools and methods / Scott A. McLuckey -- Electron capture dissociation LC/MS/MS for bottom-up proteomics / Roman A. Zubarev -- Two-dimensional ion mobility analyses of proteins and peptides / Alexandre A. Shvartsburg, Keqi Tang, and Richard D. Smith -- Proteomics for validation of automated gene model predictions / Kemin Zhou ... [et al.] -- Support vector machines for improved peptide identification from tandem mass spectrometry database search / Bobbie-Jo M. Webb-Robertson.
  • Molecular weight determination of peptides and proteins by ESI and MALDI / Kerstin Strupat -- Batch introduction techniques / Connie R. Jiménez -- In-solution digestion of proteins for mass spectrometry / Katalin F. Medzihradszky -- Identification of phosphorylation sites using microimmobilized metal affinity chromatography / Garry L. Corthals, Reudi Aebersold, and David R. Goodlett -- Mapping posttranslational modifications of proteins by MS-based selective detection : application to phosphoproteomics / Steven A. Carr, Roland S. Annan, and Michael J. Huddleston -- Characterization of protein N-glycosylation / Katalin F. Medzihradszky -- Methods in enzymology : O-glycosylation of proteins / Jasna Peter-Katalinić -- Analysis of glycosylphosphatidylinositol protein anchors : the prion protein / Michael A. Baldwin -- Comprehensive mass spectrometric analysis of the 20S proteasome complex / Lan Huang and A.L. Burlingame -- The analysis of multiprotein complexes : the yeast and the human spliceosome as case studies / Gitte Neubauer -- The use of mass spectrometry to identify antigens from proteasome processing / Odile Burlet-Schiltz ... [et al.] -- Glycosphingolipid structural analysis and glycosphingolipidomics / Steven B. Levery -- Mapping bacterial glycolipid complexity using capillary electrophoresis and electrospray mass spectrometry / J. Li ... [et al.]
  • Mass Vaccination: When and Why / D. L. Heymann and R. B. Aylward -- Mass Vaccination and Surveillance/Containment in the Eradication of Smallpox / J. M. Lane -- Mass Immunization Programs: Principles and Standards / J. D. Grabenstein and R. L. Nevin -- Immunization Campaigns in the UK / K. Noakes and D. Salisbury -- Diphtheria / C. R. Vitek -- Universal Mass Vaccination against Hepatitis A / F. E. André -- Mass Vaccination against Hepatitis B: the French Example / F. Denis and D. Levy-Bruhl -- Mass Vaccination for Annual and Pandemic Influenza / B. Schwartz and P. Wortley -- Is Global Measles Eradication Feasible? / C. A. de Quadros -- Measles Aerosol Vaccination / J. L. Valdespino-Gómez, M de Lourdes Garcia-Garcia, J. Fernandez-de-Castro, A. M. Henao-Restrepo, J. Bennett, and J. Sepulveda-Amor -- Mass Vaccination Campaigns for Polio Eradication: an Essential Strategy for Success / R. W. Sutter and C. Maher -- Rubella Mass Campaigns / S. Reef -- Mass Vaccination to Control Epidemic and Endemic Typhoid Fever / M. M. Levine -- Mass Vaccination: Solutions in the Skin / G. M. Glenn and R. T. Kenney.
  • Print Material
    1. Orbit -- 2. Ocular Motility and Cranial Nerves -- 3. Lids, Lashes, and Lacrimal Glands -- 4. Conjunctiva and Sclera -- 5. Cornea -- 6. Anterior Chamber -- 7. Iris and Pupils -- 8. Lens -- 9. Vitreous -- 10. Retina and Choroid -- 11. Optic Nerve and Glaucoma -- 12. Visual Acuity, Refractive Procedures, and Sudden Vision Loss.
  • The Massachusetts Eye and Ear Infirmary Illustrated Manual of Ophthalmology is the must-have medical reference book for the ever-changing field of ophthalmology. Thoroughly updated to include the latest advances in the field, the fourth edition of this renowned manual features high-quality color images and an intuitive design for easy comprehension and reference. Ideal for ophthalmic practitioners and allied health professionals alike, this indispensable resource is your comprehensive guide for the speedy diagnosis and treatment of the most common eye disorders. Accurately diagnose problems through the support of full-color photographs and real case studies.Rapidly locate key information with a highly templated format that includes chapters organized anatomically, not by ophthalmic subspecialty, in addition to key boxes and highlighted emergency management boxes.
  • The Massachusetts General Hospital is widely respected as one of the world's premier psychiatric institutions. Now, preeminent authorities from MGH present the newly updated edition of Massachusetts General Hospital Comprehensive Clinical Psychiatry, a unique medical reference book that continues to simplify your access to the current clinical knowledge you need - both in print and online! It provides practical approaches to a wide variety of clinical syndromes and settings, aided by stunning graphics and hundreds of questions and answers geared to each chapter. You'll have convenient access to all the authoritative answers necessary to overcome any clinical challenge.
  • Experts from the Massachusetts General Hospital-widely respected as one of the world's premier psychiatric institutions-provide practical advice on the diagnosis and treatment of psychiatric issues experienced by in-hospital, medically ill adults and children. This compact resource reads like a handbook, but delivers all the details you'd expect from a textbook. Find information quickly thanks to an improved chapter organization, and get just the answers you need with concise yet complete coverage appropriate for psychiatrists and generalists alike.
  • Neurophysiologic basis of pain / Gary Jay Brenner -- Pain mechanisms and their importance in clinical practice and research / Isabelle Decosterd and Clifford J. Woolf -- The placebo effect / Eija Kalso -- The history and clinical examination / Jan Slezak and Asteghik Hacobian -- Diagnostic imaging and pain management / Onassis A. Caneris -- Assessment of pain / Alyssa A. LeBel -- Neurophysiologic testing in pain management / Annabel D. Edwards and Lisa S. Krivickas --Nonsteroidal antiinflammatory drugs / Jane C. Ballantyne and Steven A. Barna -- Opioids / Jeffrey Uppington -- Adjuvant treatments / Karla Hayes -- Psychopharmacology for the pain specialist / Daniel M. Rockers and Karla Hayes -- Diagnostic and therapeutic procedures in pain management / Milan P. Stojanovic -- Neuromodulation techniques for the treatment of pain / Milan P. Stojanovic -- Neurosurgical pain management / Ramin Amirnovin, G. Rees Cosgrove, and Emad N. Eskandar -- Psychological assessment and behavioral treatment of chronic pain / Ronald J. Kulich and Lainie Andrew -- Physical therapy / Theresa H. Michel and Harriët Wittink -- Physiatric treatment of pain / Joseph F. Audette and Allison Bailey -- Acupuncture / Jasmin M. Field, Lucy L. Chen, and May C.M. Pian-Smith -- Chronic pain rehabilitation / Elizabeth Loder and Patricia W. McAlary -- Radiotherapy and radiopharmaceuticals for cancer pain / Thomas F. DeLaney -- Postoperative pain in adults / Jane C. Ballantyne and Elizabeth Ryder -- Postoperative pain in children / Lucy L. Chen and Jane C. Ballantyne -- Pain in burn patients / Salahadin Abdi and Bucknam McPeek -- Pain management in sickle cell disease / Jatinder Gill -- Neuropathic pain syndromes / Dennis Dey and Anne Louise Oaklander -- Complex regional pain syndrome / Eugenia-Daniela Hord -- Low back pain / James P. Rathmell ... [et al.] -- Headache / Fred Michael Cutrer and David F. Black -- Orofacial pain / Alexandre F.M. DeSilva and Martin Andrew Acquadro -- Opioids in chronic nonterminal pain / Jane C. Ballantyne -- Pain in Human Immunodeficiency Virus and Acquired Immunodeficiency Syndrome / S. Jane Marshall, Sarah Cox, and Andrew S.C. Rice -- Pain in adults with cancer / Eugenia-Daniela Hord, Jeffrey A. Norton, and Annabel D. Edwards -- Control of pain in children with chronic and terminal disease / Alyssa A. LeBel -- Palliative medicine / Constance M. Dahlin, Andrew Tyler Putnam, and J. Andrew Billings -- Long-term opioid therapy, drug abuse, and addiction / Barth L. Wilsey and Scott Fishman -- Pain and affective disorders / Daniel M. Rockers and Scott Fishman -- Emergencies in the pain clinic / Asteghik Hacobian and Milan P. Stojanovic -- Appendices.
  • Long considered important for professionals working with minority and under-represented populations, cross-cultural competency has become a requisite for all health care providers. As society in the US increasingly diversifies, there is a crucial need to prepare health care professionals to effectively treat this changing population. The Massachusetts General Hospital Textbook on Diversity and Cultural Sensitivity in Mental Health addresses the importance and relevance of cultural sensitivity in US mental health. Prominent researchers and clinicians examine the cultural and cross-cultural mental health issues of Native American, Latino, Asian, African American, Middle Eastern, Refugee and LGBQT communities. The discussion includes understanding the complexities in making mental health diagnoses and the various meanings it has for the socio-cultural group described, as well as biopsychosocial treatment options and challenges. In understanding the specific populations, the analysis delves into overarching concepts that may apply to specific populations and to those at the intersection of multiple cultures. An invaluable resource for mental health professionals, including clinicians, researchers, educators, leaders and advocates in the United States, The Massachusetts General Hospital Textbook on Diversity and Cultural Sensitivity in Mental Health provides the necessary understanding and insights for research and clinical practice in specific cultural and multicultural groups.
  • Massage. 2. Aufl. 2006
    Springer
  • Adolescent preventive services -- The adolescent patient interview -- Tanner staging -- Normal adolescent development -- Male genitourinary exam -- The pelvic exam and pap smear -- Adolescent dermatology -- Obesity -- Adolescent nutrition, IBD, IBS -- Sports injuries in the adolescent -- Cardiac issues in adolescence -- Menstrual irregularities: amenorrhea -- Menstrual irregularities: abnormal vaginal bleeding -- Basics of hormonal contraception -- Adolescent pregnancy -- Polycystic ovary syndrome -- Sexually transmitted infections in adolescents -- Delayed puberty, short stature, and tall stature -- Adolescent substance abuse -- Adolescent mental health disorders -- Eating disorders -- Adolescent relationship violence in clinical settings: challenges for identification and intervention -- Bullying -- Transition of care -- Erratum to: male genitourinary exam.
  • TheMassGeneral Hospital for Children Handbook of Pediatric Global Health is a concise resource for the ever-increasing number of health professionals involved in global health, many of whom spend a few weeks to months or even years providing medical care in resource-poor countries. This Handbook provides practical, evidence-based, hands-on guidance for managing and preventing childhood illnesses when resources are limited in low- and middle-income countries. It also offers a setting-specific understanding and management approaches to the major causes of childhood mortality, including pneumonia, diarrhea, birth asphyxia, complications of preterm birth, and neonatal sepsis. The Handbook providesan overview of childhood mortality, health systems, and the various stakeholders that play a role in the global health arena, and also contains chapters focusing on adolescents who are increasingly recognized as a unique population in whom interventions can go a long way in bothconsolidatingthe gains made in childhood and preventing adult disease. Finally, key topics in non-communicable diseases are covered, including trauma and injuries, pediatric mental health, child and adolescent rights, and oral health. Not meant solely for pediatricians, the Handbookis designed for generalists, specialists, doctors, nurses, other health care workers, and those in training. An indispensable reference for health professionals overseas, theHandbookwill also be a useful addition and resource for academic centers and universities in industrialized nations that are creating courses for trainees who will do clinical electives abroad during their training. .
  • Presenting a logical, comprehensive approach to the patient with a massive rotator cuff tear, this book begins with the pathoanatomy and diagnostic work-up for this common injury, including imaging. Both non-operative and operative treatment options for massive tears follow, including arthroscopy, the use of biologics and patches, tendon transfers, and hemiarthroplasty and reverse total shoulder arthroplasty. A practical treatment algorithm for clinicians treating patients with massive rotator cuff tears is also included. Each chapter opens with pearls and pitfalls covering the main key points for quick reference. The overarching theme of this book is that patients with similar imaging findings may demonstrate very different clinical presentations, and the final treatment recommendation should be made based on their complaints and expectations. As such, it will be an excellent resource for orthopedic surgeons, sports medicine and shoulder physicians, physiatrists, physical medicine and rehab specialists, and occupational therapists.
  • Mast cell biology : introduction and overview / Alasdair M. Gilfillan, Sarah J. Austin, and Dean D. Metcalfe -- Mast cell progenitor trafficking and maturation / Jenny Hallgren and Michael F. Gurish -- Monomeric IgE and mast cell development, survival, and function / Jun-ichi Kashiwakura, Iris M. Otani, and Toshiaki Kawakami -- Mast cell apoptosis and survival / Maria Ekoff and Gunnar Nilsson -- Regulators of Ca2+ signaling in mast cells: Potential targets for treatment of mast cell-related diseases / Hong-Tao Ma and Michael A. Beaven -- Spatio-temporal signaling in mast cells / Bridget S. Wilson, Janet M. Oliver, and Diane S. Lidke -- The mechanisms of exocytosis in mast cells / Ulrich Blank -- An emerging role for the lipid mediator sphingosine-1-phosphate in mast cell effector function and allergic disease / Ana Olivera and Juan Rivera -- Down-regulation of mast cell responses through itim containing inhibitory receptors / Laila Karra and Francesca Levi-Schaffer -- The mast cell in innate and adaptive immunity / Christopher P. Shelburne and Soman N. Abraham -- Mast cells and immunoregulation/immunomodulation / Mindy Tsai, Michele Grimbaldeston, and Stephen J. Galli -- Mast cell proteases as protective and inflammatory mediators / George H. Caughey -- Mast cells in lung inflammation / Elena P. Moiseeva and Peter Bradding -- Mast cells, angiogenesis, and cancer / Domenico Ribatti and Enrico Crivellato.
  • Mast cells and basophils 2000
    ScienceDirect
  • Mast cells are versatile, tissue-homing secretory cells, which were first described by Paul Ehrlich in 1878. Mast cells have long been implicated in the pathogenesis of allergic reactions and certain protective responses to parasites. Their functional role, however, has been discovered to be increasingly complex and multifarious. Mast cells have been implicated in various cell-mediated immune reactions, being found in tissues from multiple disease sites, and as a component of the host reaction to bacteria, parasite, and even virus infections. They have also been shown to participate to angiogenic and tissue repair processes after injury. The importance of a possible functional link between chronic inflammation and cancer has long been recognized. As most tumours contain inflammatory cell infiltrates, which often include plentiful mast cells, the question as to the possible contribution of mast cells to tumour development has progressively been emerged. In this book, the general biology of these cells, their development, anatomical distribution and phenotype as well as their secretory products will first be discussed. The biology of tumour cells, their structural and molecular characteristics, the specificity of the tumour microenvironment and the development of a vascular network in the tumour context will be analyzed. The involvement of mast cells in tumour biology and tumour fate will then be considered, with particular emphasis on the capacity of these cells to stimulate tumour growth by promoting angiogenesis and lymphangiogenesis. The last chapter suggest that mast cells may serve as a novel therapeutic target for cancer treatment.
  • Mast cells methods and protocols 2005
    Springer Protocols
    Paul Ehrlich's "Mastzellen"--from aniline dyes to DNA chip arrays : a historical review of developments in mast cell research / Harsha Vyas and Guha Krishnaswamy -- The human mast cell : an overview / Guha Krishnaswamy, Omar Ajitawi, and David S. Chi -- Mast cells in allergy and autoimmunity : implications for adaptive immunity / Gregory D. Gregory and Melissa A. Brown -- Analysis of MCT and MCTC mast cells in tissue / Lawrence B. Schwartz -- Mast cell ultrastructure and staining in tissue / Shruti A. Shukla ... [et al.] -- Expression of cell surface antigens on mast cells : mast cell phenotyping / Alexander W. Hauswirth ... [et al.] -- Identification of mast cells in the cellular response to myocardial infarction / Nikolaos G. Frangogiannis and Mark L. Entman -- Growth of human mast cells from bone marrow and peripheral blood-derived CD34+ pluripotent progenitor cells / Arnold S. Kirshenbaum and Dean D. Metcalfe -- Culture of human mast cells from hemopoietic progenitors / Hirohisa Saito -- Isolation, culture, and characterization of intestinal mast cells / Gernot Sellge and Stephan C. Bischoff -- Activation of nuclear factor kappa B / Chuanfu Li, Jim Kelley, and Tuanzhu Ha -- Analysis of mitogen-activated protein kinase activation / Stephen C. Armstrong -- Microarray and gene clustering analysis / Tsung-Hsien Tsai, Denise M. Milhorn, and Shau-Ku Huang -- Techniques to study Fc [epsilon] RI signaling / Yuko Kawakami, Jiro Kitaura, and Toshiaki Kawakami -- Human mast cell proteases : activity assays using thiobenzyl ester substrates / David A. Johnson -- Mast cell histamine and cytokine assays / David S. Chi, S. Matthew Fitzgerald, and Guha Krishnaswamy -- Measurement of mast cell cytokine release by multiplex assay / Kevin F. Breuel and W. Keith De Ponti -- Assays for histamine-releasing factors : from identification and cloning to discovery of binding partners / Jacqueline M. Langdon and Susan M. McDonald -- Assays for nitric oxide expression / William L. Stone, Hongsong Yang, and Min Qui -- Immunohistological detection of growth factors and cytokines in tissue mast cells / Zhenhong Qu -- Endothelial cell activation by mast cell mediators / Kottarappat N. Dileepan and Daniel J. Stechschulte -- Co-culture of mast cells with fibroblasts : a tool to study their crosstalk / Ido Bachelet, Ariel Munitz, and Francesca Levi-Schaffer -- Detection of E class switching and IgE synthesis in human B cells / Jérôme Péne ... [et al.] -- Gene silencing using small interference RNA in mast cells / Deling Yin and Charles A. Stuart -- Mast cell activation by lipoproteins / Jim Kelley ... [et al.] -- Mast cell activation by stress / Ann L. Baldwin -- In vivo models for studying mast cell-dependent responses to bacterial infection / Christopher P. Shelburne, James B. McLachlan, and Soman N. Abraham -- Bacterial activation of mast cells / David S. Chi ... [et al.] -- Activation of mast cells by streptolysin O and lipopolysaccharide / Michael Stassen ... [et al.] -- Mast cell apoptosis / Alexander Gerbaulet, Karin Hartmann, and Yoseph A. Mekori.
  • Periorbital Aesthetic Surgery: The Evolution of a Multidisciplinary Surgical Subspecialty -- Surgical Anatomy of the Forehead, Eyelids, and Midface for the Aesthetic Surgeon -- The Beautiful Eye: Perception of Beauty in the Periocular Area -- Critical Evaluation of the Periorbital Aesthetic Patient -- Oculofacial Anesthesia -- The Open Approach to Forehead Lifting -- Endoscopic Brow and Forehead Rejuvenation -- Direct Brow Lift: An Aesthetic Approach -- Upper Eyelid Blepharoplasty -- Adjunctive Procedures in Upper Eyelid Blepharoplasty: Internal Brow Fat Sculpting and Elevation, Glabellar Myectomy, and Lacrimal Gland Repositioning -- Management of Complications of Upper Eyelid Blepharoplasty -- Levator Ptosis Repair in the Aesthetic Patient With and Without Blepharoplasty -- Posterior Approach Ptosis Repair in the Aesthetic Patient With or Without Blepharoplasty -- Modern Advances in Asian Blepharoplasty -- Transcutaneous Lower Eyelid Blepharoplasty -- Transconjunctival Lower Blepharoplasty: Fat Excision or Repositioning -- Managing the Lateral Canthus in the Aesthetic Patient -- Management of the Post-lower Eyelid Blepharoplasty Retracted Eyelid -- Laser Management of Festoons -- Midface and Lower Eyelid Rejuvenation -- Face Implants in Aesthetic Surgery -- Periorbital Fat Grafting -- Periorbital Laser Resurfacing -- Laser Incisional Eyelid Surgery -- Neuromodulators and Fillers for Periorbital Rejuvenation -- Management of the Prominent Eye -- Postoperative Wound Modulation in Aesthetic Eyelid and Periorbital Surgery -- Short-Flap Superficial Musculo-Aponeurotic System (SMAS) Rhytidectomy.
  • This new resource helps you choose the best approach and get the best results for any facial rejuvenation challenge! Renowned facial plastic, plastic, and oculoplastic surgeons and dermatologists present multiple, competing and complementary, time-tested facial rejuvenation techniques. Each chapter is a step-by-step, illustrative depiction of the author's surgical techniques, with emphasis on minimally invasive surgery, recent trends, and adjunctive procedures. The book focuses on all areas of the face in order to produce a balanced and systematic approach for facial rejuvenation. An accompanying surgical atlas on 2 DVDs shows digitally videotaped procedures. Details procedures step by step using a highly illustrated color format. Includes discussions of the authors' most challenging cases and their technical pearls and pitfalls. Keeps you current with proven innovations such as minimal invasive facelift, new facial implants, and laser resurfacing options. BONUS Video Atlas accomanies the book, bringing you two DVDs of surgical procedures performed by the experts!
  • A concise yet comprehensive, multi-authored, multi-specialty surgical text and video atlas that provides all the guidance you need to get the best outcomes in rhinoplasty. Babak Azizzadeh, MD, FACS and other leading experts guide you through both open and endonasal primary and secondary rhinoplasty techniques with the use of step-by-step procedures, color line drawings, intraoperative photographs, and narrated videos on DVD. Performed the latest open and endonasal techniques for both primary and revision rhinoplasty and give your patients the outstanding results they demand. Choose the most promising approach based on multiple expert viewpoints on the advantages and disadvantages of each approach. Review history, personal philosophy, anatomy, preoperative analysis, technique, and postoperative care, and complication avoidance for each procedure - all the information you need to get the best outcomes. Master the nuances of each new technique through step-by-step instructions and beautiful, detailed line drawings and intraoperative photographs. Watch master surgeons perform techniques in narrated videos on the included DVD's. Tap into the experience and expertise of leading reconstructive and cosmetic plastic surgeons.
  • Print Material
    Internal medicine -- Preventive medicine -- Dermatology -- Surgery -- Pediatrics -- Obstetrics -- Gynecology -- Radiology -- Psychiatry -- Emergency medicine/toxicology -- Ethics.
  • Key issues of vascular pathoanatomy / Frank Kolodgie ... [et al.] -- Key issues of vascular pathophysiology / Axel R. Pries, Ivo Buschmann, Helmut Habazettl -- Magnetic resonance imaging / Dietrich Baumgart, Thomas Egelhof -- X-ray coronary angiography / Peter Lanzer -- Intracoronary ultrasound / Anuja Nair ... [et al.] -- Pressure wire / Wilbert Aarnoudse, Cees-joost Botman, Nico H.J. Pijls -- The decision-making process in percutaneous coronary interventions / Lutz Prechelt, Peter Lanzer -- Devices / Wolfram Schmidt, Klaus-Peter Schmitz -- Intracranial vessels / Hans Henkes ... [et al.] -- Internal carotid artery / Peter Lanzer, Ralf Weser -- Coronary arteries / Peter Lanzer, L.D. Timmie Topoleski -- Thoracic aorta / Tim C. Rehders ... [et al.] -- Abdominal aortic aneurysm / Martin Köcher, Petr Utíkal -- Renal arteries / Peter Lanzer, Ralf Weser -- Abdominal aorta, iliac, and lower extremity arteries / Peter Lanzer, Ralf Weser -- Haemodialysis shunts / Dierk Vorwerk -- Venous diseases / Zubin Irani, John A. Kaufman -- Foreign bodies / Haresh G. Mehta, Stephan Windecker, Bernhard Meier.
  • Mastering Perl 2007
    ProQuest Safari
  • Introduction to regular expressions -- Extended introductory examples -- Overview of regular expression features and flavors -- The mechanics of expression processing -- Practical regex techniques -- Crafting an efficient expression -- Perl -- Java -- .NET -- PHP.
  • Simplifying Rhinoplasty -- A Basic Rhinoplasty Operation -- Radix and Dorsum -- TechniqTueips -- Nasal Base -- Functional Factors -- Grafts -- Primary Rhinoplasty: Decision Making -- Advanced Primary Rhinoplasty -- Secondary Rhinoplasty: Surgical Techniques -- Secondary Rhinoplasty: Decision Making -- Aesthetic Reconstructive Rhinoplasty.
  • This self-help guide is intended for scientists and medical professionals and students who wish to improve their scientific writing skills. Exercises invite the reader to practice the most important aspects of scientific writing. Although the book addresses certain issues more troublesome to scientific communicators of a non-English language origin, the guide will be of equal benefit to those whose first language is English. If you want not only to write but to write well, this book is for you. This second edition takes into account new developments in the area of scientific communication. In particular, the importance of authenticity is addressed, drawing attention to the sensitive issue of plagiarism in scientific texts.
  • Foundations of simulation -- Developing clinical competence and confidence -- Creating effective simulation environments -- Creating effective, evidence-based scenarios -- Debriefing and reflective practice -- Evaluating simulation effectiveness -- Using simulation with specific learner populations -- Using health care simulation for interprofessional -- Using simulation in academic environments to improve -- Using simulation in hospitals and health care systems -- Using simulation for risk management and quality -- Using simulation for research -- Defining roles and building a career in simulation -- Credentialing and certification in simulation -- Developing and building a simulation center -- The future of simulation in health care.
  • This volume in the acclaimed Mastery Series delivers clear, how-to guidance on the most commonly performed procedures in adult and pediatric thoracic surgery. As with other volumes in the series, Mastery of Cardiothoracic Surgery delivers expert commentary from master surgeons following each chapter. Invaluable for cardiothoracic fellows, as well as thoracic and cardiac surgeons. Comprehensive text follows the Mastery style--with comments from the expert editors at the end of each chapter to help hone technique, improve results, and minimize error. Procedure-based chapters address critical details--from indications and preoperative assessment to surgical technique, postsurgical follow-up, and management of complications. Broad coverage addresses thoracic, adult cardiac, and congenital cardiac procedures to prepare readers for any challenge. NEW to the Third Edition ... Full-color design and art enliven the text and facilitate visual learning. New chapters address key disorders and surgical interventions--including Ascending Aortic Aneurysms, Minimally Invasive Maze Procedure, Reoperative Cardiac Surgery, Repair of Esophageal Hernia, Repair of Pectus Deformities, Thoracic Sympathectomy, and Percutaneous Mitral and Aortic Valve Repairs. Companion website provides access to the fully searchable text and images from the book.--Provided by publisher.
  • Print Material
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    v. 1. Nemesius, Proclus, k︠h︡osrovig, Epiphanius and Secundus. 1895. (294 p.)
  • 1. Evidence-based Anticancer Materia Medica for Lung Cancer / Constance L.L. Saw, Lita S.J. Chew, and Xiaofeng G. Cai -- 2. Evidence-based Anticancer Materia Medica for Colorectal Cancer / Minsig Choi, Ramzi Mohammad, M. Wasif Saif, and Richard Kim -- 3. An Overview of the Current Development of Phytoremedies for Breast Cancer / Chun-Hung Lin, Wai-Leng Lee, and Lie-Fen Shyur -- 4. Evidence-based Anticancer Kampo Medicine for Gastric Cancer / Koji Tanaka, Takeshi Omori, and Toshiro Nishida -- 5. Evidence-based Anticancer Materia Medica for Hepatocellular Carcinoma / Lei Wan -- 6. Evidence-based Anticancer Materia Medica for Prostate Cancer / Yi-Ren Chen, Pei-Wen Hsiao, Feng-Ming Lin, Guan-James Wu, and Chin-Hsien Tsai -- 7. Evidence-based Anticancer Materia Medica for Cervical Cancer / Tatjana Stanojković, Aleksandra Konić-Ristić, Teodora Janković, Gordana Zdunić, and Katarina Šavikin -- 8. Evidence-based Anticancer Materia Medica for Esophageal Cancer / Taixiang Wu, Minawaer Abudou, and Shou Chen -- 9. Evidence-based Anticancer Materia Medica for Lymphoma / Eran Ben-Arye, Tamar Tadmor, Aaron Polliack, and Elad Schiff -- 10. Evidence-based Anticancer Materia Medica for Bladder Cancer / Dawei Ye, Pingping Gu, Hongyu Zhao, Michelle Chow, Xiaoqing Guo, and Jianyu Rao -- 11. Evidence-based Anticancer Materia Medica for Pancreatic Cancer / Shwu-Huey Liu and M. Wasif Saif -- 12. Evidence-based Anticancer Materia Medica for Leukemia / Min Li-Weber -- 13. Evidence-based Anticancer Materia Medica for Nasopharyngeal Carcinoma / Guangcun Deng, Jihui Yang, and Yujiong Wang -- 14. Evidence-based Anticancer Materia Medica for Brain Tumors / Prabha Balaram and Faizah Harun -- 15. Evidence-based Materia Medica for Cancer Chemoprevention / Sunil Prabhu, Ying Huang, and Jeffrey Wang -- 16. Pharmacokinetics of Anticancer Materia Medica in Humans / Shu-Feng Zhou.
  • David Riley's interest in the history, methodology, and results of homeopathic drug provings came from his study of homeopathy at the Hahnemann College of Homeopathy in Albany, California. The 69 drug homeopathic drug provings published here, are the result of his investigation of the research methods of homeopathic drug provings that forms part of the basis for prescribing in homeopathy. In Dr. Hahnemann's time the method by which the treatment profiles of homeopathic remedies were determined were called provings, after the original German word Prüfung, which means "test". Scientific research methods have evolved from the early days of homeopathy and Dr. Riley, in an attempt to improve transparency and reduce bias, has incorporated elements of contemporary research methods such as randomization, blinding, and formal good clinical practice guidelines (GCP) into homeopathic drug provings, while adhering to the general guidelines suggested by Dr. Hahnemann and used by homeopathic practitioners and researchers around the world.
  • A history of international cooperation in maternal and child health -- Global burden of disease among women, children, and adolescents -- Promotion of global perinatal health -- Maternal and child health in the organization for economic cooperation and development (OECD) countries -- Health system impacts on maternal and child health -- The environment and maternal child health -- Impact of wars and conflict on maternal and child health -- The impact of globalization on maternal and child health -- Gender equity: perspectives on maternal and child health -- Harmful traditional practices and women's health: female genital mutilation -- Abortion and postabortion care -- Malaria in women and children -- The global burden of childhood diarrhea -- Tuberculosis in childhood and pregnancy -- Impact of HIV on the health of women, children, and families in less developed countries -- Malnutrition and maternal and child health -- The global burden of obstetric fistulas -- Health challenges for women, children, and adolescents with disabilities -- Unintentional injuries in children -- Evidence-based maternal and child health -- A global perspective on teen pregnancy -- Progress and challenges in making pregnancy safer: a global perspective -- Global immunization challenge: progress and opportunities -- Adolescent health -- The global burden of child maltreatment -- Children in difficult circumstances -- Integrated management of childhood illness -- Planning, development, and maintenance of the MCH workforce -- An agenda for child health policy in developing countries.
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    Children's rights, distributive justice, and advocacy in maternal and child health / Lewis Margolis, George Cole, Jonathan Kotch -- Historical foundations of maternal and child health / Lewis Margolis, George Cole, Jonathan Kotch -- Families and health / Joseph Telfair -- Family planning / C.Arden Miller, Linda Piccinino, Amy Tsui -- Mothers and infants / Trude Bennett, Milton Kotelchuck -- The child from 1 to 4: the toddler and preschool years / Anita M. Farel, Jonathan B. Kotch -- The school-age child / Joseph Telfair, Jonathan B. Kotch -- Improving adolescent health / David Knopf -- Disparities in maternal and child health in the United States / Larry Crum ... [et al.] -- Women's health: a life cycle / B. Cecilia Zapata, Anjel Vahratian, Trude Bennett -- Children and youth with special health care needs / Anita M. Farel -- Issues in maternal and child health nutrition / Janice Dodds, Barbara Laraia -- International maternal and child health / Sian Curtis, Shelah Bloom, Elizabeth Sutherland -- Research issues in maternal and child health / Greg R. Alexander ... [et al.] -- Planning maternal and child health programs / Mary D. Peoples-Sheps -- Maternal and child health program monitoring and performance appraisal / Mary D. Peoples-Sheps, Joseph Telfair -- The practice of evaluation research in maternal and child health / Joseph Telfair -- Advocacy and policy development in maternal and child health / Donna J. Petersen, Catherine Hess.
  • Growth and nutrition during the fetal period and the first 24 months after birth are important determinants of development in early childhood. Optimal nutrition and health care of both the mother and infant during these first 1000 days of an infant's life are closely linked to growth, learning potential and neurodevelopment, in turn affecting long-term outcomes. Children with low birth weight do not only include premature babies, but also those with intrauterine growth restrictions who consequently have a very high risk of developing metabolic syndrome in the future. Epidemiology, epigenetic programming, the correct nutrition strategy and monitoring of outcomes are thus looked at carefully in this book. More specifically, two important nutritional issues are dealt with in depth: The first being the prevention of low birth weight, starting with the health of adolescent girls, through the pre-pregnancy and pregnancy stages and ending with lactation. The second point of focus concerns the nutritional follow-up and feeding opportunities in relation to dietary requirements of children with low birth weight.
  • Maternal care
    Wellcome Trust
  • Brave new world : the intrauterine environment as the biological foundation for the lifespan -- In the beginning -- Maternal influences on the developing fetus -- Implications of maternal programming for fetal neurodevelopment -- Maternal thyroid function during pregnancy: effects on the developing fetal brain -- Obstetric factors related to perinatal brain injury -- Activation of the maternal immune system as a risk factor for neuropsychiatric disorders -- Prenatal infections and schizophrenia in later life: focus on toxoplasma gondii -- Maternally acting alleles in autism and other neurodevelopmental disorders: the role of HLA-DR4 within the major histocompatibility complex.
  • Epidemiology of Diabetes and Obesity in Pregnancy / Robert Lindsay -- Fertility and Obesity / Ulrik Schiøler Kesmodel -- Clinical Consequences of Abnormal Glucose Metabolism / Dorte M. Jensen, Per Glud Ovesen and Patrick Catalano -- Clinical Management / Jenny Myers and Michael Maresh -- Physical Activity and Pregnancy / Bente Klarlund Pedersen -- Miscarriage and Malformations / Montserrat Balsells, Apolonia García-Patterson and Rosa Corcoy -- Maternal Obesity and Pregnancy / Michael Conall Dennedy and Fidelma Dunne -- Gestational Weight Gain / Christina Anne Vinter -- Maternal Diabesity and Developmental Programming in the Offspring / Thomas Harder, Joachim W. Dudenhausen and Andreas Plagemann -- Obesity in Pregnancy and Ultrasound / Ute M. Schaefer-Graf -- Maternal Obesity and Macrosomia / Kinneret Tenenbaum-Gavish and Moshe Hod -- Shoulder Dystocia in Maternal Obesity / Polly Weston, Jo Crofts and Tim Draycott -- Stillbirth and Infant Mortality / Ellen Aagaard Nohr -- Anaesthesia in Maternal Obesity / Ulla Bang and H. Soren Helbo-Hansen -- Macrosomia and Neonatology / Bartolomé Bonet -- Childhood Obesity: The Impact of Maternal Obesity on Childhood Obesity / Rebecca M. Reynolds -- Obesity in Pregnancy: Data from the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study / Harold David McIntyre, Lynn P. Lowe, Alan R. Dyer and Boyd E. Metzger -- Breastfeeding and Obesity: Impact on Women and Their Children / Tessa Crume and Dana Dabelea -- Pregnancy Following Bariatric Surgery / Isabelle Guelinckx, Roland Devlieger and Greet Vansant.
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  • v. I. Cellular biophysics, regulatory networks, development, biomedicine, and data analysis -- v. 2. Epidemiology, evolution and ecology, immunology, neural systems and the brain, and innovative mathematical methods and education.
  • Preface -- Thymocyte development -- A review of mathematical models for T cell receptor triggering and antigen discrimination -- Dynamic tuning of T cell receptor specificity by co-receptors and costimulation -- T cell activation and function: role of signal strength -- The cyton model for lymphocyte proliferation and differentiation -- Modeling itravital two-photon data of lymphocyte migration and interaction -- Modeling lymphocyte dynamics in vivo -- Continuous-time birth and death processes: diversity maintenance of naïve T cells in the periphery -- Multivariate competition processes: a model for two competing T cell clonotypes -- Stochastic modeling of T Cell homeostasis for two competing clonotypes via the master equation -- Dendritic cell migration in the intestinal tract -- Reassessing germinal center reaction concepts -- B cell strategies of Ag recognition in a stratified immune system -- Dynamics of Peripheral regulatory and effector T cells competing for antigen presenting cells -- Mathematical models of the role of IL-2 in the interactions between helper and regulstory CD4+ T cells -- A Physicist{u2019}s approach to immunology -- Timescales of the adaptive immune response -- Using mathematical models to explore the role of cytoxic T lymphocytes in HIV infection -- Viral immunity and persistence -- Index.
  • Mathematical neuroscience 2014
    ScienceDirect
    Mathematical Neuroscience is a book for mathematical biologists seeking to discover the complexities of brain dynamics in an integrative way. It is the first research monograph devoted exclusively to the theory and methods of nonlinear analysis of infinite systems based on functional analysis techniques arising in modern mathematics. Neural models that describe the spatio-temporal evolution of coarse-grained variables-such as synaptic or firing rate activity in populations of neurons -and often take the form of integro-differential equations would not normally reflect an integrative approach. This book examines the solvability of infinite systems of reaction diffusion type equations in partially ordered abstract spaces. It considers various methods and techniques of nonlinear analysis, including comparison theorems, monotone iterative techniques, a truncation method, and topological fixed point methods. Infinite systems of such equations play a crucial role in the integrative aspects of neuroscience modeling. The first focused introduction to the use of nonlinear analysis with an infinite dimensional approach to theoretical neuroscience. Combines functional analysis techniques with nonlinear dynamical systems applied to the study of the brain. Introduces powerful mathematical techniques to manage the dynamics and challenges of infinite systems of equations applied to neuroscience modeling.
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    Note datasets in every format including R and SAS.
  • Passive isopotential cell -- Differential equations -- Active isopotential cell -- Quasi-active isopotential cell -- Passive cable -- Fourier series and transforms -- Passive dendritic tree -- Active dendritic tree -- Reduced single neuron models -- Probability and random variables -- Synaptic transmission and quantal release -- Neuronal calcium signaling -- Singular value decomposition and applications -- Quantification of spike train variability -- Stochastic processes -- Membrane noise -- Power and cross spectra -- Natural light signals and phototransduction -- Firing rate codes and early vision -- Models of simple and complex cells -- Stochastic estimation theory -- Reverse-correlation and spike train decoding -- Signal detection theory -- Relating neuronal responses and psychophysics -- Population codes -- Neuronal networks -- Solutions to selected exercises.
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  • Basic operations -- Data handling -- Plotting data -- Start programming -- A better sound -- Create and process images -- Data analysis -- The charm of graphical user interface -- Psychtoolbox : video -- Psychtoolbox : sound, keyboard and mouse.
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  • MATLAB primer. 6th ed. 2002
    CRCnetBASE
  • MATLAB primer. 7th ed. 2005
    CRCnetBASE
  • pt. 1. Introduction to programming using MATLAB -- Introduction to Matlab -- Vectors and matrices -- Introduction to MATLAB programming -- Selection statements -- Loop statements and vectorizing code -- MATLAB programs -- String manipulation -- Data structures : cell arrays and structures -- Advanced file input and output -- Advanced functions -- pt. 2. Advanced topics for problem solving with MATLAB -- Advanced plotting techniques -- Basic statistics, sets, sorting, and indexing -- Sights and sounds -- Advanced mathematics.
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    1. Bd. 1460-1529 -- 2. Bd. 1532/33-1600/01 -- 3. Bd. 1601/02-1665/66 -- 4. Bd. 1666/67-1725/26 -- 5. Bd. 1726/27-1817/18.
  • Matrix Metalloproteinases / Viola Vargová, Marek Pytliak and Viola Mechírová -- Specificity of Binding with Matrix Metalloproteinases / Satya P. Gupta and Vaishali M. Patil -- The Gelatinases and Their Inhibitors: The Structure-Activity Relationships / Snehasikta Swarnakar, Amartya Mishra and Susri Ray Chaudhuri (Guha) -- Advances in Studies on Collagenase Inhibitors / Mange Ram Yadav, Prashant Revan Murumkar and Vishal Prakash Zambre -- Hydroxamic Acids as Matrix Metalloproteinase Inhibitors / Rajeshwar P. Verma -- Quantitative Structure-Activity Relationship Studies on Sulfonamide-Based MMP Inhibitors / Vaishali M. Patil and Satya P. Gupta -- Matrix Metalloproteinase Inhibitors as Investigative Tools in the Pathogenesis and Management of Vascular Disease / Mina M. Benjamin and Raouf A. Khalil.
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    al-Mawrid -- [Physiology of the human body] -- Lamps of experience: a collection of English proverbs with origins and Arabic equivalents -- English words of Arabic origin -- Biographical names.
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    Trauma -- Oncology -- Craniofacial deformity -- Oral surgery.
  • Offers complete coverage of maxillofacial trauma highlighted by an unparalleled collection of outstanding, full-color photographs, and highly detailed line drawings that clarify surgical procedures. Addresses secondary surgery in a dedicated section, covering such topics as facial scar management; secondary osteotomies and bone grafting to correct deformities; bone distraction, used commonly with congenital malformations; secondary rhinoplasty for traumatic nasal deformities, which are associated with a variety of cosmetic and functional issues; secondary orbital surgery; facial nerve injuries; and psychological support for patient with facial trauma. Features an outstanding, full-color art program, with more than 750 color photos that cover all aspects of injury and treatment, and 250 color line drawings that walk you step by step through surgical procedures. Includes contributions from a "who's who" list of international experts in oral and maxillofacial surgery, psychology, ophthalmology, neurosurgery, plastic surgery, and craniofacial surgery. Relates brain injury to the overall management of the face for both function and esthetics. Contains updated guidelines on facial fractures, expanded information on psychological problems following facial trauma, and a new chapter on pediatric trauma.
  • pt. 1. Marine by-products characterisation, recovery and processing: 1. Physical and chemical properties of protein seafood by-products / T. Rustad ; 2. Physical and chemical properties of lipid by-products from seafood waste / J.P. Kerry and S.C. Murphy ; 3. On-board handling of marine by-products to prevent microbial spoilage, enzymatic reactions and lipid oxidation / E. Falch, M. Sandbakk and M. Aursand ; 4. Recovery of by-products from seafood processing streams / J.A. Torres ... [et al.] ; 5. Increasing processed flesh yield by recovery from marine by-products / K.D.A. Taylor and A. Himonides ; 6. Enzymatic methods for marine by-products recovery / F. Guerard ; 7. Chemical processing methods for protein recovery from marine by-products and underutilized fish species / H.G. Kristinsson, A.E. Theodore and B. Ingadottir -- pt. 2. Food uses of marine by-products: 8. By-catch, underutilized species and underutilized fish parts as food ingredients / I. Batista ; 9. Mince from seafood processing by-product and surimi as food ingredients / J.-S. Kim and J.W. Park ; 10. Aquatic food protein hydrolysates / H.G. Kristinsson ; 11. Engineering and functional properties of powders from underutilized marine fish and seafood products / S. Sathivel and P.J. Bechtel ; 12. Marine oils from seafood waste / F. Shahidi ; 13. Collagen an gelatin from marine by-products / J.M. Regenstein and P. Zhou ; 14. Seafood flavor from processing by-products / C.M. Lee ; 15. Fish and bone as a calcium source / S.-K. Kim and W.-K. Jung ; 16. Chitin and chitosan from marine by-products / F. Shahidi ; 17. Marine enzymes from seafood by-products / M.T. Morrissey and T. Okada ; 18. Antioxidants from marine by-products / F. Shahidi and Y. Zhong ; 19. Pigments from by-products of seafood processing / B.K. Simpson -- pt. 3. Non-food uses of marine by-products: 20. By-products from seafood processing for aquaculture and animals feeds / P.J. Bechtel ; 21. Using marine by-products in pharmaceutical, medical and cosmetic products / J. Losso ; 22. Bio-diesel and bio-gas production from seafood processing by-products / R. Zhang and H.M. El-Mashad ; 23. Composting of seafood wastes / A.M. Martin.
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  • The leading prosthodontics resource for more than 40 years, this book provides the information you need to successfully manage the replacement of missing teeth. It covers the basic principles of treatment planning and design, and discusses the newest techniques, procedures, and equipment. Well-known educators Alan B. Carr, DMD, MS, and David T. Brown, DDS, MS use an evidence-based approach that helps you diagnose, design, develop, and sequence a treatment plan. A new chapter in this edition explains how to select and use implants to improve prosthesis performance. From initial contact with the patient to post-treatment care, from basic concepts to advanced material, this full-color text provides a complete foundation in prosthodontic care.
  • A text in pediatric dentistry, McDonald and Avery's provides expert, complete coverage of oral care for infants, children, and teenagers. All the latest diagnostic and treatment recommendations are included! Comprehensive discussions are provided on pediatric examination, development, morphology, eruption of the teeth, and dental caries. This edition helps you improve patient outcomes with up-to-date coverage of restorative materials, cosmetic tooth whitening, care of anxious patients, and sedation techniques for children. Complete, one-source coverage includes the best patient outcomes for all of the major pediatric treatments in prosthodontics, restorative dentistry, trauma management, occlusion, gingivitis and periodontal disease, and facial esthetics. A new Pediatric Oral Surgery chapter discusses the latest developments in office-based pediatric oral surgery, along with head and neck infections and medical conditions in the pediatric patient. An Evolve website includes case studies, an image library, links to ADEA, ADA, and CDC reports on pediatric dentistry, and other web links.
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  • Symptoms and differential diagnosis -- Evaluation tools -- Anatomy and physiology -- Diseases and problems -- Operative techniques -- Nonsurgical management -- Perioperative management.
  • 1. Thyroid nodule -- 2. Goiter -- 3. Hyperthyroidism --4. Papillary thyroid carcinoma -- 5. Follicular thyroid carcinoma and oncocytic (Hürthle cell) carcinoma -- 6. Medullary thyroid carcinoma -- 7. Anaplastic thyroid carcinoma, metastases to the thyroid gland, and thyroid lymphoma -- 8. Primary hyperparathyroidism -- 9. Persistent and recurrent hyperparathyroidism -- 10. Secondary and tertiary hyperparathyroidism -- 11. Parathyroid Carcinoma -- 12. Incidentalomas and metastases to the adrenal gland -- 13. Hyperaldosteronism -- 14. Hypercortisolism -- 15. Pheochromocytoma and paraganglioma -- 16. Adrenocortical carcinoma -- 17. Insulinoma -- 18. Gastrinoma -- 19. Carcinoid tumors -- 20. Other functional and nonfunctional neuroendocrine tumors -- 21. Multiple endocrine neoplasia Ttype 1 -- 22. Multiple endocrine neoplasia type 2 -- 23. von Hippel-Lindau disease.
  • v. 1. The structure and function of skin -- Specialized techniques in dermatopathology -- Disorders of keratinization -- Inherited and autoimmune subepidermal blistering diseases -- Acantholytic disorders -- Spongiotic, psoriasiform and pustular dermatoses -- Lichenoid and interface dermatitis -- Superficial and deep perivascular inflammatory dermatoses -- Granulomatous, necrobiotic and perforating dermatoses -- Inflammatory diseases of the subcutaneous fat -- Diseases of the oral mucosa -- Diseases of the anogenital skin -- Degenerative and metabolic diseases -- Cutaneous adverse reactions to drugs -- Neutrophilic and eosinophilic dermatoses -- Vascular diseases -- Idiopathic connective tissue disorders -- Infectious diseases of the skin -- v.2. Human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS)-associated cutaneous diseases -- Disorders of pigmentation -- Diseases of collagen and elastic tissue -- Diseases of the hair -- Diseases of the nails -- Tumors of the surface epithelium -- Melanocytic nevi -- Melanoma -- Tumors of the conjunctiva -- Sentinel node biopsies -- Cutaneous lymphoproliferative diseases and related disorders -- Cutaneous metastases and Paget's disease the skin -- Tumors of the hair follicle -- Tumors and related lesions of the sebaceous glands -- Tumors of the sweat glands -- Cutaneous cysts -- Connective tissue tumors.
  • Systemic review -- Skeleton -- Muscles -- Arteries -- Veins -- Nerves -- Dermatomes -- Cross-sections of the human body -- Head, neck, and brain -- Skull -- Skull bones -- Neck -- Root of the neck -- Face -- Temporal and infratemporal fossae -- Infratemporal fossa -- Deep infratemporal fossa -- Pharynx -- Larynx -- Cranial cavity -- Eye -- Nose -- Nose and tongue -- Ear -- Brain -- Cranial nerves -- Clinical thumbnails -- Vertebral column and spinal cord -- Vertebral column overview -- Back and shoulder -- Vertebrae -- Sacrum -- Sacrum and coccyx -- Bony pelvis -- Vertebral ossification -- Vertebral column and spinal cord -- Surface anatomy of the back -- Muscles of the back -- Sub-occipital triangle -- Vertebral radiographs -- Clinical thumbnails -- Upper limb -- Upper limb overview -- Upper limb bones -- Shoulder -- Axilla -- Arm -- Elbow -- Forearm -- Hand -- Wrist and hand radiographs -- Clinical thumbnails -- Thorax -- Thorax overview -- Thoracic bones -- Thoracic wall surface markings and breast -- Breast -- Thoracic wall and surface markings -- Thoracic wall -- Thoracic viscera -- Heart -- Mediastinum -- Mediastinal imaging -- Lungs -- Superior mediastinum -- Superior mediastinum and thoracic inlet -- Superior thoracic aperture (thoracic inlet) -- Posterior mediastinum -- Intercostal nerves and thoracic joints -- Aorta and associated vessels -- Diaphragm -- Oesophageal imaging -- Clinical thumbnails -- Abdomen and pelvis -- Abdomen overview -- Anterior abdominal wall -- Male pelvis -- Inguinal region -- Upper abdomen -- Intestinal imaging -- Liver -- Gall bladder imaging -- Spleen -- Spleen and intestines -- Intestines -- Small intestine -- Kidneys and suprarenal glands -- Kidneys and kidney imaging -- Diaphragm and posterior abdominal wall -- Posterior abdominal and pelvic walls -- Pelvic walls -- Male inguinal region, external genitalia -- Male pelvis -- Pelvic vessels and nerves -- Pelvic ligaments -- Female pelvis -- Female perineum -- Male perineum -- Clinical thumbnails -- Lower limb -- Lower limb overview -- Lower limb bones -- Foot bones -- Foot and ankle bones -- Ankle bones -- Development of lower limb bones -- Gluteal region -- Thigh -- Front of thigh -- Hip joint -- Knee -- Knee radiographs -- Leg -- Ankle and foot -- Foot -- Ankle and foot imaging -- Clinical thumbnails -- Lymphatics -- Lymphatic system -- Lymphangiography -- Thymus -- Chest -- Palatine tonsils -- Neck -- Thoracic duct -- Right anilla -- Cisterna chyli and thoracic duct -- Female pelvis -- Gross lymphadenopathy of the pelvis -- Thigh and superficial inguinal lymph nodes -- Clinical thumbnails.
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  • Bari M. Logan and Ralph T. Hutchings, uses phenomenal images of dissections, osteology, and radiographic and surface anatomy to provide you with a perfect grasp of all the lower limb structures you are likely to encounter in practice or in the anatomy lab. You'll have an unmatched view of muscles, nerves, skeletal structures, blood supply, and more, plus new, expanded coverage of regional anesthesia injection sites and lymphatic drainage. Unlike the images found in most other references, all of these illustrations are shown at life size to ensure optimal visual comprehension. It's an ideal resource for clinical reference as well as anatomy lab and exam preparation! Easily correlate anatomy with clinical practice through 200 high-quality illustrations, many life-sized, including dissection photographs, skeletal illustrations, surface anatomy photos, and radiologic images. Reinforce your understanding of each dissection with notes and commentaries, and interpret more complex images with the aid of explanatory artwork. Efficiently review a wealth of practical, high-yield information with appendices on skin, arteries, muscles, and nerves. Administer nerve blocks accurately and effectively with the aid of a new chapter on regional anesthesia.
  • Skull and skull bone articulations -- Sect: Skull -- Bones of the skull -- Skull bone articulations -- Fetal skull -- Cervical vertebrae and neck -- Sect: Cervical vertebrae -- Other bones -- Neck -- Face, orbit and eye -- Sect: Face -- Orbit and eye -- Nose, oral region, ear and larynx -- Sect: Nose and paranasal sinuses -- Mouth, palate and pharynx -- Ear -- Larynx -- Cranial cavity and brain -- Sect: Cranial cavity -- Brain -- Radiographs -- Sect: Radiographs.
  • Catalysis and multi-component reactions -- Multi-component reactions in heterocyclic chemistry -- Multi-component reactions in drug discovery -- Novel reagents for multi-component reactions -- Design of multi-component reactions -- Multi-component reactions in supramolecular chemistry and material science.
  • Part I. Leukemia -- Chapter 1. Acute Lymphoblastic Leukemia -- Chapter 2. Adult Acute Myeloid Leukemia -- Chapter 3. Chronic Lymphocytic Leukemia and Associated Disorders -- Chapter 4. Chronic Myeloid Leukemia -- Chapter 5. Myelodysplastic Syndromes: The MD Anderson Cancer Center Approach -- Chapter 6. Philadelphia Chromosome-Negative Myeloproliferative Neoplasms -- Part II. Lymphoma and Myeloma -- Chapter 7. The Indolent Lymphomas -- Chapter 8. Aggressive and Highly Aggressive B-Cell Lymphomas -- Chapter 9. T-Cell Lymphomas -- Chapter 10. Hodgkin Lymphoma -- Chapter 11. Multiple Myeloma and Other Plasma Cell Dyscrasias -- Part III. Stem Cell Transplantation -- Chapter 12. Allogeneic Transplantation -- Chapter 13. Autologous Stem Cell Transplantation -- Part IV. Lung Cancer -- Chapter 14. Small Cell Carcinoma of the Lungs -- Chapter 15. Non-Small Cell Lung Cancer -- Part V. Head and Neck Cancer -- Chapter 16. Head and Neck Cancer -- Part VI. Gastrointestinal Carcinomas -- Chapter 17. Gastric and Esophageal Cancer -- Chapter 18. Pancreatic Cancer -- Chapter 19. Hepatobiliary Malignancies -- Chapter 20. Small Bowel Cancer and Appendiceal Tumors -- Chapter 21. Colorectal Cancer -- Chapter 22. Anal Cancer -- Chapter 23. Neuroendocrine Tumors -- Part VII. Breast Cancer -- Chapter 24. Early-Stage and Locally Advanced Breast Cancer -- Chapter 25. Metastatic Breast Cancer -- Chapter 26. Inflammatory Breast Cancer -- Chapter 27. Special Situations in Breast Cancer -- Part VIII. Gynecologic Malignancies -- Chapter 28. Ovarian Cancer -- Chapter 29. Tumors of the Uterine Corpus -- Chapter 30. Tumors of the Uterine Cervix -- Chapter 31. Gestational Trophoblastic Tumors -- Part IX. Genitourinary Carcinoma -- Chapter 32. Renal Cell Carcinoma -- Chapter 33. Bladder Cancer -- Chapter 34. Prostate Cancer -- Chapter 35. Penile Cancer -- Chapter 36. Germ Cell Tumors -- Part X. Miscellaneous Tumors -- Chapter 37. Tumors of the Central Nervous System -- Chapter 38. Endocrine Malignancies -- Chapter 39. Malignant Melanoma -- Chapter 40. Soft Tissue and Bone Sarcomas -- Chapter 41. The AIDS-Related Cancers -- Chapter 42. Carcinoma of Unknown Primary -- Part XI. Supportive Care -- Chapter 43. Infection in the Neutropenic Patient -- Chapter 44. Fungal and Viral Infections in Cancer Patients -- Chapter 45. Endocrine and Metabolic Complications of Cancer Therapy -- Chapter 46. Oncologic Emergencies -- Part XII. Palliative Care and Symptom Management -- Chapter 47. Defining Palliative Care in Oncology -- Chapter 48. Pain Management and Symptom Control -- Part XIII. Long-Term Survival -- Chapter 49. Pediatric Long-Term Follow-Up -- Chapter 50. Adult Long-Term Follow-Up -- Chapter 51. Rehabilitation.
  • "The current edition of The Handbook provides an overview of current care of patients with cancer diagnoses commonly evaluated and treated by surgical oncologists, and in doing so continues to align such care with the underlying philosophy of the Department of Surgical Oncology at M.D. Anderson: multidisciplinary, cooperative care is the ideal way to manage patients with cancer. Such care begins with an understanding of the underlying tumor biology and natural history of the disease and includes technical excellence in the delivery of indicated surgical treatment. It also demands integration of essential information from the available literature on currently preferred treatment modalities, and emphasizes appropriate inclusion of adjunctive specialty care, including medical oncology, radiation oncology, interventional radiology, palliative care, pain management, physical therapy, nutritional support, social services and nursing"--Provided by publisher.
  • MDCT anatomy body 2011
    Springer
    Lungs and Interstitial Network -- Airways -- Pulmonary Arteries and Veins -- Aorta and Supra-aortic Trunks -- Bronchial Arteries and Vena Cava -- Pleura and Pericardium -- Mediastinal Compartments, Lymphatic System, and Esophagus -- Heart and Coronary Arteries -- Chest Wall -- Diaphragm and Abdominal and Pelvic Walls -- Peritoneal Cavity -- Splanchnic Arteries -- Iliac Arteries and Abdominal Aorta -- Renal Arteries -- Inferior Vena Caval System -- Venous Portal Circle -- Abdominal Lymphatic System -- Gastroduodenal Tract -- Small Intestine -- Colon -- Liver -- Biliary System -- Spleen -- Extraperitoneal Spaces -- Pancreas -- Adrenal Glands -- Kidneys and Ureters -- Urinary Bladder -- Bony Pelvis -- Muscular Pelvis and Pelvic Floor -- Pelvic Space -- Female Pelvis: Uterus, Ovaries, and Ligaments -- Prostate and Seminal Vescicles.
  • The new series A-Z Notes in Radiological Practice and Reporting provides practical guides for residents and general radiologists, organized alphabetically, primarily according to disease or condition. All booklets are designed so as to comprise only a small number of illustrations and to cover a large spectrum of topicsreferring to different anatomical regions of interest. The first volume on cardiac CT and MR imaging contains all the practical suggestions that can help a radiologist in the execution and reporting of a cardiac examination. The book is structured to offer an easy and fast consultation on cardiac imaging and pathology with the use of tables and figures. Entries typically include a short description of pathological and clinical characteristics, guidance on selection of the most appropriate imaging technique, a schematic review of potential diagnostic clues, and useful tips and tricks.
  • Multidetector-row computed tomography (MDCT) has become a fundamental imaging technique for the study of many anatomical districts in different clinical situations, as it provides a fast, reliable, and accurate simultaneous evaluation of different organs, including parenchyma, hollow viscera, vessels, and bony structures. It has also equipped the radiologist with the ability to explore areas that in the last decade were largely ignored by CT, especially the coronary arteries and the colon, and to limit invasive diagnostic tests (e.g., catheter angiography) to those cases in which interventional procedures are required. The examination quality and the consequent diagnostic accuracy of MDCT are the results of an optimized study technique, which nonetheless needs to be adapted to the particular clinical situation of the patient, while bearing in mind the radiation exposure. Another fundamental parameter in the optimization of MDCT is the protocol for the intravenous injection of iodinated contrast material; in these studies, multiple variables, some modifiable by the operator and others patient-dependent, must be considered based on the aims of maximizing arterial and venous enhancements whilst minimizing the dose of iodine injected, saving money, and increasing patient safety. Through the presentation of cases addressing different anatomical regions and various clinical indications, including emergency and neuro-imaging, this volume seeks to provide the general radiologist and trainee specialist with a guide to the main study protocols to be implemented in order to optimize examination quality and, consequently, facilitate the diagnostic process.
  • The book introduces a radically new way of thinking about information and the important role it plays in living systems. It opens up new avenues for exploring how cells and organisms change and adapt, since the ability to detect and respond to meaningful information is the key that enables them to receive their genetic heritage, regulate their internal milieu, and respond to changes in their environment. It also provides a way of resolving Descartes{u2019} dilemma by explaining the workings of the brain in non-mechanical terms that are not tainted by spiritual or metaphysical beliefs. The types of meaningful information that different species and different cell types are able to detect are finely matched to the ecosystem in which they live, for natural selection has shaped what they need to know to function effectively in those circumstances. Biological detection and response systems range from the chemical configurations that govern genes and cell life to the relatively simple tropisms that guide single-cell organisms, the rudimentary nervous systems of invertebrates, and the complex neuronal structures of mammals and primates. The scope of meaningful information that can be detected and responded to reaches its peak in our own species, as exemplified by our special abilities in language, cognition, emotion, and consciousness, all of which are explored within this new framework.
  • Last Acts is a national coalition to improve care and caring near the end of life. This report describes the state of dying in America, comparing states on several elements of end of life care such as the use of advance care directives, hospice use, hospital end-of-life care services, care in ICUs, and pain among the dying. Case studies are used to supplement the state-by-state comparison.
  • Broad considerations in the relation of means and ends, treating, and healing -- Cognitive semantic structures in informal means/ends reasoning -- Health and disease: fluid concepts evolved non-literally -- John Dewey's perspectives on means and ends: the setting which makes informal deliberation necessary -- John Dewey's view of situations, problems, means, and ends -- Preference, utility and value in means and ends reasoning -- Full spectrum means and ends reasoning.
  • John F. Enders and measles virus vaccine : a reminiscence / S.L. Katz -- Measles virus receptors / Y. Yanagi ... [et al.] -- Measles virus and CD46 / C. Kemper and J.P. Atkinson -- Measles virus glycoprotein complex assembly, receptor attachment, and cell entry / C.K. Navaratnarajah, V.H.J. Leonard and R. Cattaneo -- The measles virus replication cycle / B.K. Rima and W.P. Duprex -- Nucleocapsid structure and function / S. Longhi -- Reverse genetics of measles virus and resulting multivalent recombinant vaccines : applications of recombinant measles viruses / M.A. Billeter, H.Y. Naim and S.A. Udem -- Measles virus interaction with host cells and impact on innate immunity / D. Gerlier and H. Valentin.
  • Making it to the synapse : measles virus spread in and among neurons / V.A. Young and G.F. Rall -- Modeling subacute sclerosing panencephalitis in a transgenic mouse system : uncoding pathogenesis of disease and illuminating components of immune control / M.B.A. Oldstone -- Measles studies in the macaque model / R.L. de Swart -- Ferrets as a model for morbillivirus pathogenesis, complications, and vaccines / P. Pillet, N. Svitek and V. von Messling -- Current animal models : cotton rat animal model / S. Niewiesk -- Current animal models : transgenic animal models for the study of measles pathogenesis / C.I. Sellin and B. Horvat -- Molecular epidemiology of measles virus / P.A. Rota, D.A. Featherstone, and W.J. Bellini -- Human immunology of measles virus infections / D. Naniche -- Measles control and the prospect of eradication / W.J. Moss -- Measles : old vaccines, new vaccines / D.E. Griffin and C.-H. Pan -- Measles virus for cancer therapy / S.J. Russell and K.W. Peng -- Measles virus-induced immunosuppression / S. Schneider-Schaulies and J. Schneider-Schaulies -- Hostile communication of measles virus with host innate immunity and dendritic cells / B. Hahm.
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    v. 1. Measuring nursing performance in practice, education, and research -- v. 2. Client outcomes and quality of care -- v. 3. Self care and coping.
  • 1. Methods for identifying and evaluating quality spine measurements -- 2. How the spine measurements are displayed in this book -- 3. Clinical measurements -- 4. Laboratory measurements -- 5. Radiographic measuements -- Glossary of terms and abbreviations.
  • The Importance of Vascular Investigation and Intervention in Leg Ulcer Management / Colin Davies and Keith Poskitt -- Diabetic Foot Disease and Wound Healing / Agbor Ndip and Edward B. Jude -- Atypical Ulcers / Jennifer Tang and Robert S. Kirsner -- Nutrition and Wound Healing / Giuseppe Benati and Maria S. Bertone -- Measurement of Wound Healing and Tissue Repair / Visweswar Bhattacharya, Nilesh K. Agarwal and Siddhartha Bhattacharya -- Pressure Ulcers in Neurologically Compromised Patients / Anbananden Soopramanien and Shivram Singh -- Complications of Wound Healing / Somprakas Basu and Vijay Shukla -- Epidemiology of Wounds / David J. Margolis -- Histopathology of Wounds / Mariya Miteva and Paolo Romanelli -- Measuring Pressure in the Diabetic Foot / Thanh Dinh, Aristidis Veves and Francesco Tecilazich -- Skin and Vascular Assessments / Marco Romanelli, Valentina Dini and Raj Mani -- Wound Tissue Oximetry: A Cornerstone in Wound Care / Jaideep Banerjee and Chandan K. Sen -- Measurement of Biomarkers for Impaired Healing in Fluids and Tissues / Gregory S. Schultz and Daniel J. Gibson -- Measurements in Burns / Tom McKinnell and Sarah A. Pape -- Managing Scars: Measurements to Improve Scar Management / Luc Téot, Claude Roques, Sami Otman, Antonio Brancati and Rainer Mittermayr -- The Use of Biophysical Technologies in Chronic Wound Management / Uwe Wollina, Birgit Heinig and Luther Kloth -- Research Studies in Wound Healing: The Role of Outcomes/Endpoints for the Evidence in RCTs / Finn Gottrup, Jan Apelqvist and Patricia Price -- Models in Wound Healing / Ming Yuan Miao, Ting Xie, Shuliang Lu and Raj Mani.
  • v. 1. Couples, families, and children -- v. 2. Adults.
  • "Emphasizing applications over theory, this book provides a comprehensive survey of this method and provides readers with standards and directions on how to run sound clinical and other types of studies. The author clearly explains how to reduce measurement error and presents numerous practical examples of the interobserver agreement approach. To help with problem solving, he includes SAS code, both within the book and on the CRC website. An extensive review of the literature offers access to the latest developments in the field. This edition presents new applications, new tables, more detail on SAS, new code, updated references, and two new chapters"--Provided by publisher.
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    The theoretical and technical foundations of health measurement -- Physical disability and handicap -- Social health -- Psychological well-being -- Anxiety -- Depression -- Mental status testing -- Pain measurements -- General health status and quality of life -- Recommendations and conclusion.
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  • MHC class I -- MHC class II -- Cytokine receptor heterogeneity -- Genetic diversity at human cytokine loci in health and disease -- Signaling molecules affecting immune response -- Toll-like receptors in innate immunity -- DNA sequence-specific transcription factors -- Genetic diversity in NK and NKT cells -- Handling sera and obtaining fluid from different compartments -- Acute-phase proteins and inflammation -- Complement in health and disease -- Immunoglobulin titers and immunoglobulin subtypes -- Human antiglobulin responses -- Rheumatoid factors -- Autoantibodies -- Antibody affinity using fluorescence -- SLE-associated tests -- Multiplexed serum assays -- Handling and storage of cells and sera: practical considerations -- Phenotypic and functional measurements on circulating immune cells and their subsets -- Natural killer cells -- Tetramer analysis -- Peripheral blood naive and memory B cells -- Dendritic cells -- Monocytes and macrophages -- Tumor cells -- Regulatory T cells -- Intracellular cytokine assays -- Cytolytic assays -- Mixed leukocyte reactions -- Antigen/mitogen-stimulated lymphocyte proliferation -- Monitoring cell death -- Cytokine enzyme linked immunosorbent spot (ELISPOT) assay -- Testing natural killer cells -- Delayed type hypersensitivity responses -- Rebuck windows: granulocyte function -- The vascular and coagulation systems -- Sentinel node assays -- Imaging inflammation -- Cancer - solid tumors -- Cancer - hematologic disorders -- Autoimmunity - rheumatoid arthritis -- Autoimmunity - type 1 diabetes -- Autoimmunity - systemic lupus erythematosus -- Autoimmunity - multiple sclerosis -- Autoimmunity - inflammatory bowel disease -- Autoimmunity - endocrine -- Autoimmunity - vasculitis -- Transplantation -- Viral responses - HIV-1 -- Viral responses - epstein-barr virus -- Viral responses - hepatitis -- Dermatology -- Arteriosclerosis -- Primary immunodeficiencies -- Asthma and allergy -- Serum proteomic profiling and analysis -- Imaging cytometry -- Cancer biometrics -- Genomics and microarrays -- Image informatics.
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    A framework for measuring professionalism / David Thomas Stern -- What is medical professionalism? / Louise Arnold and David Thomas Stern -- Ethics, law, and professionalism: what physicians need to know / Audiey Kao -- Using standardized clinical encounters to assess physician communication / Debra Klamen and Reed Williams -- The assessment of moral reasoning and professionalism in medical education and practice / DeWitt C. Baldwin Jr. and Donnie J. Self -- Using surveys to assess professionalism in individuals and institutions / DeWitt C. Baldwin Jr. and Steven R. Daugherty -- Measuring specific elements of professionalism: empathy, teamwork, and lifelong learning / Jon Veloski and Mohmmmedreza Hojat -- Faculty observations of student professional behavior / John Norcini -- Using critical incident reports and longitudinal observations to assess professionalism / Maxine Papadakis and Helen Loeser -- Content and context of peer assessment / Louise Arnold and David Thomas Stern -- Using reflection and rhetoric to understand professional behaviors / Shiphra Ginsburg and Lorelei Lingard -- The use of portfolios to assess professionalism / Kelly Fryer-Edwards, Linda E. Pinsky, and Lynne Robins -- Admission to medical school: selecting applicants with the potential for professionalism / Norma E. Wagoner -- Assessing professionalism for accreditation / Dierdre C. Lynch, David C. Leach, and Patricia M. Surdyk -- Measuring professionalism: a commentary / Fred Hafferty.
  • Historical aspects of mechanical circulatory support -- Potential population for long-term use of left ventricular assist devices -- Acute decompensated heart failure -- Pathophysiology of stage D heart failure -- Risk factors for mortality with heart failure -- Candidate selection for long-term left ventricular assist device therapy for advanced heart failure -- Preoperative patient optimization for mechanical circulatory support -- Current types of devices for mechanical circulatory support -- Special clinical settings for mechanical circulatory support -- Perioperative anesthetic management for ventricular assist device implantation -- Surgical methods for mechanical circulatory support -- Intraoperative management issues in mechanical circulatory support -- Adverse events and complications of mechanical circulatory support -- Predischarge and outpatient management -- Psychosocial and quality-of-life issues in mechanical circulatory support -- Myocardial recovery with use of ventricular assist devices -- Regenerative therapy as an adjunct to mechanical support -- Biologic responses to the interface between device and circulation: bleeding and thrombosis with mechanical circulatory support -- Cellular, molecular, genomic and functional changes that occur in the failing heart in response to mechanical circulatory support -- Results of clinical trials to date -- Design challenges for clinical trials in mechanical circulatory support -- Role of government agencies in mechanical circulatory support: FDA -- INTERMACS (Interagency Registry for Mechanically Assisted Circulatory Support) as a tool to track and advance clinical practice -- Reimbursement and funding framework for mechanical circulatory support -- Future of mechanical circulatory support.
  • Mechanical testing is a useful tool in the field of biomechanics. Classic biomechanics employs mechanical testing for a variety of purposes. For instance, testing may be used to determine the mechanical properties of bone under a variety of loading modes and various conditions including age and disease state. In addition, testing may be used to assess fracture fixation procedures to justify clinical approaches. Mechanical testing may also be used to test implants and biomaterials to determine mechanical strength and appropriateness for clinical purposes. While the information from a mechanical test will vary, there are basics that need to be understood to properly conduct mechanical testing. This book will attempt to provide the reader not only with the basic theory of conducting mechanical testing, but will also focus on providing practical insights and examples.
  • The Importance of Acute Respiratory Failure in the ICU -- The Epidemiology of Mechanical Ventilation -- Long-term Outcomes of Mechanical Ventilation -- Understanding and Changing the Practice of Mechanical Ventilation in the Community -- Control of Breathing During Mechanical Ventilation -- Patient-ventilator Interactions -- Physiological Rationale for Ventilation of Patients with Obstructive Diseases -- Role of the Clinician in Adjusting Ventilator Parameters During Assisted Ventilation -- Neurally-adjusted Ventilatory Assist -- Liberating Patients from Mechanical Ventilation: What Have we Learned About Protocolizing Care? -- Novel Approaches to Monitoring Mechanical Ventilatory Support -- Indications for Non-invasive Ventilation -- Non-invasive Ventilation: Causes of Success or Failure -- Non-invasive Ventilation in Immunocompromised Patients -- Biophysical Factors Leading to VILI -- Vascular Contribution to VILI -- VILI: Physiological Evidence -- Systemic Effects of Mechanical Ventilation -- Chest Wall Mechanics in ARDS -- Targets in Mechanical Ventilation for ARDS -- How to Detect VILI at the Bedside? -- Lung Morphology in ARDS: How it Impacts Therapy -- Recruitment Maneuvers in ARDS -- Spontaneous Breathing During Ventilatory Support in Patients with ARDS -- Pressure-support Ventilation in Patients with ALI/ -- Prone Ventilation -- Adjuncts to Mechanical Ventilation for ARDS including Biological Variability -- Summary of Clinical Trials of Mechanical Ventilation in ARDS.
  • "One of the key tools in effectively managing critical illness is the use of mechanical ventilator support. This essential text helps you navigate this rapidly evolving technology and understand the latest research and treatment modalities. A deeper understanding of the effects of mechanical ventilation will enable you to optimize patient outcomes while reducing the risk of trauma to the lungs and other organ systems."--Publisher's website.
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    Classification of mechanical ventilators / Robert L. Chatburn, Richard D. Branson -- Modes of ventilator operation / Richard D. Branson -- The patient-ventilator interface : ventilator circuit, airway care, and suctioning / Richard D. Branson -- Humidification and aerosol therapy / Richard D. Branson -- Ventilator monitors and displays / Neil R. MacIntyre -- Respiratory system mechanics / Neil R. MacIntyre -- Alveolar-capillary gas transport / Neil R. MacIntyre -- Patient-ventilator interactions / Lawrence R. Tom, Catherine S.H. Sassoon -- Cardiopulmonary interactions / David N. Hager, Henry E. Fessler -- Ventilator-induced lung injury / Renee D. Stapleton, Kenneth P. Steinbert -- Nutrition / Richard D. Branson, Jay A. Johannigman -- Sedation, analgesia, and neuromuscular blockade / Bryan A. Fisk, Lisa K. Moores -- Patient positioning / Joseph A. Govert -- Ventilator-associated pneumonia / Mohammed Hijazi, Mariam Al-Ansari -- Management of parenchymal lung injury / Neil R. MacIntyre -- Management of obstructive airway disease / Neil R. MacIntyre -- Unique patient populations / John H. Sherner, Lisa K. Moores -- Discontinuing mechanical ventilation / Neil R. MacIntyre -- Prolonged mechanical ventilation / Christopher E. Cox, Shannon S. Carson -- Mechanical ventilation during transport and cardiopulmonary resuscitation / Richard D. Branson, Jay A. Johannigman -- Noninvasive mechanical ventilation / Nicholas S. Hill -- Modifications on conventional ventilation techniques / John D. Davies -- High-frequency ventilation / Michael A. Gentile, Neil R. MacIntyre -- Extracorporeal techniques for cardiopulmonary support / Michael A. Gentile, Ira M. Cheifetz -- Heliox and inhaled nitric oxide / Dean R. Hess -- Appendix 1. Mechanical ventilation case studies / Neil R. MacIntyre -- Appendix 2. Assessment question answers -- Glossary.
  • The volume dwells on the major issues of mechanical stress influencing the ion channels and intracellular signaling pathways. This book is a unique collection of reviews outlining current knowledge and future developments in this rapidly growing field. In our opinion the book presents not only the latest achievements in the field but also brings the problem closer to the experts in related medical and biological sciences as well as practicing doctors. Knowledge of the mechanisms which underlie these processes is necessary for understanding of the normal functioning of different living organs and tissues and allows to predict changes, which arise due to alterations of their environment, and possibly will allow to develop new methods of artificial intervention. We also hope that presenting the problem will attract more attention to it both from researchers and practitioners and will assist to efficiently introduce it into the practical medicine.
  • This book offers a state-of-the-art description of the complexity of the healthy and pathological respiratory system, with particular reference to the mechanics of the airways, lung and chest wall. Detailed information is provided on new insights into the mechanics of breathing that have been obtained through technological innovations in measurement systems, cutting-edge modeling techniques and novel approaches to functional imaging of the respiratory system. It is explained how these advances permit the assessment of emerging treatment approaches, including new drugs, innovative surgical techniques and modes of mechanical ventilation and new forms of rehabilitation. In order to ensure comprehensive coverage of the subject, the editor has assembled a multidisciplinary team of authors comprising basic scientists in respiratory medicine, chest and intensive care physicians and bioengineers involved in both modeling and instrumentation. The book is intended for intensive care physicians, respirologists, physiologists, rehabilitation specialists, basic scientists in respiration, research and clinical fellows, biomedical engineers involved with respiratory mechanics and respiratory therapists. They will update their knowledge and improve their clinical expertise.
  • Introduction to bone materials -- Basic bone remodeling theory -- Multifield internal bone remodeling -- Multifield surface bone remodeling -- Theoretical models of bone modeling and remodeling -- Effect of parathyroid hormone on bone metabolism -- Cortical bone remodeling under mechanical stimulus -- Bone remodelling under pulsed electromagnetic fields and clinical applications -- Experiments.
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    1. Effect on skeletal muscle vessels.
  • Tremor is intimately linked to the numerous interactions of the central and peripheral nervous system components tuning motor control, from the cerebral cortex up to the peripheral effectors. Activities of central generators, reflex loop delays, inertia, stiffness and damping are all factors influencing features of tremor. This book discusses the pathophysiology of tremor including membrane mechanisms and rodent models, the advances in genetics and the musculoskeletal models pertinent to body oscillations. The main forms of tremor encountered during clinical practice are considered, taking into account neuroimaging aspects. The book covers recent advances in methodologies and techniques of assessment, and provides practical informations for the daily management. In addition to pharmacological treatments, neurosurgical approaches such as deep brain stimulation (DBS) and thalamotomy are discussed. Emerging techniques under development are also introduced. Future challenges are also presented.
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    "This new volume covers the basics of pain neurobiology and reviews evidence on the mechanisms of action of physical therapy treatments as well as their clinical effectiveness in specific pain syndromes. It is a comprehensive textbook for the management of pain for the physical therapy student and the practicing physical therapist"--Provided by publisher.
  • Cell volume regulatory mechanisms an introduction / Friedrich, B., Matskevich, I., Lang, F. -- Cell volume-sensitive chloride channels : phenotypic properties and molecular identity / Okada, Y. -- Cell volume-regulated cation channels / Wehner, F. -- Sensors and signal transduction pathways in vertebrate cell volume regulation / Hoffmann, E.K., Pedersen, S.F. -- Activation of kinases upon volume changes : role in cellular homeostasis / Alexander, R.T., Grinstein, S. -- Tonicity dependent regulation of osmoprotective genes in mammalian cells / Ferraris, J.D., Burg, M.B. -- Ion channels and cell volume in regulation of cell proliferation and apoptotic cell death / Lang, F., Shumilina, E. ... [et al.] -- Cell volume regulatory ion transport in the regulation of cell migration / Jakab, M., Ritter, M. -- Cell volume regulation in the renal papilla / Beck, F.-X., Neuhofer, W. -- Osmosensing and signaling in the regulation of liver function / Schliess, F., Hussinger, D. -- Cell volume and peptide hormone secretion / Strbák, V. -- Volume changes in neurons : hyperexcitability and neuronal death / Pasantes-Morales, H., Tuz, K. -- Pathophysiology of red cell volume / Browning, J.A., Ellory, J.C., Gibson, J.S.
  • The role of hormesis in life extension by dietary restriction / E.J. Masoro -- Metabolic reprogramming in dietary restriction / R.M. Anderson, R. Weindruch -- Secrets of the lac operon: glucose hysteresis as a mechanism in dietary restriction, aging, and disease / C.V. Mobbs ... [et al.] -- Effects of dietary restriction on the expression of insulin-signaling-related genes in long-lived mutant mice / A. Bartke ... [et al.] -- Anti-inflammatory mechanisms of dietary restriction in slowing aging processes / T.E. Morgan, A.M. Wong, C.E. Finch -- Dietary restriction in the nematode caenorhabditis elegans / K. Houthoofd ... [et al.] -- Diet restriction in drosophila melanogaster / M. Tatar -- Dietary restriction in aging nonhuman primates / J.A. Mattison ... [et al.] -- Caloric intake and Alzheimer's disease: experimental approaches and therapeutic implications / G.M. Pasinetti ... [et al.] -- Can short-term dietary restriction and fasting have a long-term anticarcinogenic effect? / S. Klebanov.
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    Molecular and cell biology / Julian R. E. Davis -- Gaucher's disease : a model disorder for therapeutic exploration of the lysosome / Timothy M. Cox -- Obesity / J. Shaker, P.G. McTernan, and Sudesh Kumar -- Autoimmune mechanisms / Anthony P. Weetman -- Mechanisms of disease : allergy and anaphylaxis / Richard S.H. Pumphrey -- Infection : bacterial / Stephen D. Lawn and George E. Griffin -- Infection : parasitic / Malcolm E. Molyneux -- The acute coronary syndrome / Anthony M. Heagerty -- Heart failure / Ludwig Neyses and Mamta H. Buch -- Acute neurodegeneration : cerebral ischaemia and stroke / Craig J. Smith ... [et al.] -- Diabetic neuropathy / Adam Greenstein ... [et al.] -- Renal cell carcinoma / Wasat Mansoor -- Alcoholic liver disease / James Neuberger -- Diet, health and disease / Michael E.J. Lean -- Trauma / Nick Payne and David W. Yates -- The interaction between organic and psychiatric disease / Else Guthrie.
  • This textbook aims to describe the fascinating area of eukaryotic gene regulation for graduate students in all areas of the biomedical sciences. Gene expression is essential in shaping the various phenotypes of cells and tissues and as such, regulation of expression is a fundamental aspect of nearly all processes in physiology, both in healthy and in diseased states. This pivotal role for the regulation of gene expression makes this textbook essential reading from students of all the biomedical sciences in order to be better prepared for their specialized disciplines. A complete understanding of transcription factors and the processes that alter their activity is a major goal of modern life science research. The availability of the whole human genome sequence (and that of other eukaryotic genomes) and the consequent development of next-generation sequencing technologies have significantly changed nearly all areas of the biological sciences. For example, the genome-wide location of histone modifications and transcription factor biding sites, such as provided by the ENCODE consortium, has greatly improved our understanding of gene regulation. Therefore, the focus of this book is the description of the post-genome understanding of gene regulation. The purpose of this book is to provide, in a condensed form, an overview on the present understanding of the mechanisms of gene regulation.
  • Insulin and IGF-I receptor structure and binding mechanism / Pierre de Meyts ... [et al.] -- Subcellular compartmentalization of insulin signaling processes and GLUT4 trafficking events / Robert T. Watson ... [et al.] -- Regulation of insulin action and insulin secretion by snare-mediated vesicle exocytosis / Debbie C. Thurmond -- Control of protein synthesis by insulin / Joseph F. Christian and John C. Lawrence -- Hepatic regulation of fuel metabolism / Catherine Clark and Christopher B. Newgard -- Insulin action gene regulation / Calum D. Sutherland, Richard M. O'Brien, and Daryl K. Granner -- Insulin action in the islet B-cell / Rohit N. KulkarnI -- Central regulation of insulin sensitivity / Silvana Obici and Luciano Rossetti -- Transgenic models of impaired insulin signaling / Francesco Oriente and Domenico Accili -- Insulin resistance / C. Hamish Courtney and Jerrold M. Olefsky.
  • This book represents the first step at beginning to put together the complex puzzle of the molecular basis of memory. Sweatt creates a framework of thinking about synaptic plasticity and memory at the molecular level; one which recognizes and begins to incorporate this extreme biochemical complexity into our thinking about memory.
  • Morphogenesis is the set of processes that generate shape and form in the embryo--an important area within developmental biology. An exciting and up-to-the-minute account of the very latest research into the factors that create biological form, Mechanisms of Morphogenesis, second edition is a text reference on the mechanisms of cell and tissue morphogenesis in a diverse array of organisms, including prokaryotes, animals, plants and fungi. By combining hard data with computer modeling, Mechanisms of Morphogenesis, second edition equips readers with a much broader understanding of the scope of modern research than is otherwise available. The book focuses on the ways in which the genetic program is translated to generate cell shape, to direct cell migration, and to produce the shape, form and rates of growth of the various tissues. Each topic is illustrated with experimental data from real systems, with particular reference to gaps in current knowledge and pointers to future. Includes over 200 four-color figures. Offers an integrated view of theoretical developmental biology and computer modelling with laboratory-based discoveries. Covers experimental techniques as a guide to the reader. Organized around principles and mechanisms, using them to integrate discoveries from a range of organisms and systems.
  • 1. Cytokines and Stressors: Implications for Cancer Immunotherapy -- 2. The Role of Oncogene Activation in Tumor Progression -- 3. Carcinogenic Effects of Ionising Radiation -- 4. Chemical Carcinogenesis Role of Chloroform Further Studies -- 5. Use of Organ Explant and Cell Culture in Cancer Research -- 6. Chromosomal Abnormalities in Selected Hematopoietic Malignancies Detected by Conventional and Molecular Cytogenetics: Diagnostic and Prognostic Significance -- 7. Mechanisms of Cancer Growth and Progression in Lymphoma -- 8. Pediatric Cancer Mechanisms of Cancer Growth and Progression -- 9. Carcinogenetic Pathway of Malignant Melanoma -- 10. Ewing Sarcoma: Molecular Characterization and Potential Molecular Therapeutic Targets -- 11. Molecular Mechanisms of Central Nervous System Metastasis -- 12. Carcinogenesis of Human Papillomavirus in Head and Neck Squamous Cell Carcinoma -- 13. Postmenopausal Hormone Replacement Therapy and Breast Cancer Clinicopathologic Associations and Molecular Mechanisms -- 14. Carcinogenesis of Lung Cancer -- 15. Genesis of Barretts Neoplasia: Current Concepts -- 16. Genesis of Pancreatic Ductal Neoplasia -- 17. Recent Advances in the Pathogenesis of Pancreatic Endocrine Neoplasms -- 18. Mechanisms of Carcinogenesis in Colorectal Cancer -- 19. Carcinogenetic Pathway of Superficial Low-Grade Urothelial Carcinoma -- 20. Carcinogenetic Pathway of Urothelial Carcinoma -- 21. Mechanisms of Carcinogenesis in Prostate Cancer -- 22. HPV in Cervical Carcinoma -- Index.
  • 1 Age and racial variation in the prevalence of open-angle glaucoma in the USA -- 2 Epidemiology of and risk factors for primary open-angle glaucoma -- 3 The Reykjavik Eye Study on prevalence of glaucoma in Iceland and identified risk factors -- 4 Defined glaucoma in Chinese population -- 5 The Wroclaw Epidemiological Study screening possibilities of glaucoma detection -- 6 Pretrabecular mechanisms of intraocular pressure elevation -- 7 Glaucomatous changes in the trabecular meshwork -- 8 Trabecular mechanisms of intraocular pressure elevation Pseudoexfoliation syndrome -- 9 Post-trabecular glaucomas with elevated episcleral venous pressure -- 10 Angle-closure glaucoma: anterior (pulling) mechanisms -- 11 Angle-closure glaucomas: posterior (pushing) mechanisms with pupillary block -- 12 Angle-closure glaucomas: posterior (pushing) mechanisms without pupillary block -- 13 Genetics and glaucoma susceptibility -- 14 Myocilin mutations and their role in open-angle glaucoma -- 15 The functional role of myocilin in glaucoma -- 16 Roles of CYP1B1, optineurin, and WDR36 gene mutations in glaucoma -- 17 Genetic association in the open-angle glaucomas -- 18 ApoE polymorphisms and severity of open-angle glaucoma. 19 Changes in aqueous humor dynamics with age and glaucoma -- 20 Mechanosensitive genes in the trabecular meshwork at homeostasis: elevated intraocular pressure and stretch -- 21 Reactive astrocytes in the glaucomatous optic nerve head protective and destructive mechanisms -- 22 Optic neuropathy and ganglion cell degeneration in glaucoma -- 23 Proteomics in defining pathogenic processes involved in glaucomatous neurodegeneration in glaucoma: mechanisms and therapeutic strategies -- 24 Proteomics advances toward understanding mechanisms of glaucoma pathology -- 25 Molecular and cellular responses in the eye to glaucoma: ocular gene expression in experimental glaucoma -- 26 Ocular biomechanics in glaucoma -- 27 Intraocular pressure, perfusion pressure, and optic nerve energy metabolism -- 28 Optic nerve: physiology and mechanisms of glaucomatous atrophy -- 29 Psychophysiology of glaucoma -- 30 The primate model of experimental glaucoma -- 31 Involvement of inflammation in a mouse model of inherited pigmentary glaucoma -- 32 Use of purified retinal ganglion cells for an in vitro model to study glaucoma -- 33 pharmacological therapies for managing glaucoma -- 34 Redox-based therapies for neuroprotection -- 35 Neuroprotective signaling pathways in glaucoma -- 36 Role of selective laser trabeculoplasty in the management of glaucoma -- 37 Mechanisms and mechanics of incisional surgery for glaucoma -- 38 Aqueous shunts -- 39 New approaches to the surgical management of the glaucomas.
  • Mechanosensitivity of cells from various tissues -- Mechanotransduction in the Nematode Caenorhabditis elegans -- Mechanically mediated crosstalk in heart -- Swelling-and stretch-activated chloride channels in the heart: regulation and function -- Role of stretch-activated channels in the heart: action potential and Ca2+ transients -- Isolated cardiomyocytes: mechanosensitivity of action potential, membrane current and ion concentration -- Mechano-electric feedback in the heart: evidence from intracellular microelectrode recordings on multicellular preparations and single cells from healthy and diseased tissue -- The Role of mechanosensitive fibroblasts in the heart -- Mechanical modulation of intracellular ion concentrations: mechanisms and electrical consequences -- Stretch-induced slow force response in mammalian ventricular myocardium -- The Na+/H+ exchanger as the main protagonist following myocardial stretch: the Anrep effect and myocardial hypertrophy -- Mechano-electric feedback and atrial arrhythmias -- The Role of mechano-electrical feedback in the cholinergic atrial fibrillation initiation --; Mechanosensitive cation channels of leech neurons -- Mechanosensitivity of primary afferent nociceptors in the pain pathway -- Stimulus-secretion coupling in the osmoreceptive prolactin cell of the tilapia -- Stretch-inactivated channels in skeletal muscle -- Stretch-activated cation channels and the myogenic response of small arteries -- Mechanobiology of bone tissue and bone cells -- Functional roles of mechanosensitive ion channels, ss1 integrins and kinase cascades in chondrocyte mechanotransduction -- Enigmatic roles of the epithelial sodium channel (ENaC) in articular chondrocytes and osteoblasts: mechanotransduction, sodium transport or extracellular sodium sensing?
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    Takes the reader step-by-step through the entire med school process--from thinking about, applying to, and choosing a medical school and program, through the four-year curriculum, internships, residencies, and fellowships, to choosing a speciality and finding the perfect job.
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    General principles -- Behavioral science -- Biochemistry -- Molecular biology, genetics, and cell biology -- Immunology -- Microbiology -- Embryology -- Physiology -- Pathology -- Pharmacology/therapeutics. Organ systems -- The nervous system -- The cardiovascular system -- The respiratory system -- The renal and urinary system -- The gastrointestinal system -- The endocrine system -- The reproductive system -- The musculoskeletal system, skin, and connective tissue -- The hematologic and lymphoreticular system.
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  • This atlas systematically reviews motor conduction studies of the median nerve, from pilot human studies in peripheral nerve conduction during the 1950s through to the most recent scientific evidence. Descriptions are provided of a wealth of motor nerve conduction techniques that were reproduced in the laboratory, including both the originally proposed methods and variants. The techniques are organized according to practical criteria for ease of reference. Attention is focused especially on those techniques which have shown higher sensitivity and specificity in the diagnosis of compressive mononeuropathies like carpal tunnel syndrome (CTS)and on the most widely accepted guidelines, recommendations, quality measures, and electrodiagnostic classifications. The volume is completed with a detailed, well-illustrated glossary explaining the more commonly used terms in electrodiagnostic medicine (EDX). The atlas is primarily intended for residents and professionals in Neurology, as well as rehabilitation physicians and clinical neurophysiologists. The detailed descriptions of techniques and their practical use will also make the book an invaluable tool for novices and clinical neurophysiology technicians.
  • This atlas systematically reviews sensory conduction studies of the median nerve, from pilot human studies in peripheral nerve conduction during the 1950s through to the most recent scientific evidence. Descriptions are provided of a wealth of sensory nerve conduction techniques that were reproduced in the laboratory, including both the originally proposed methods and variants. The methods are organized according to practical criteria for ease of reference. Attention is focused especially on those techniques which have shown higher sensitivity and specificity in the diagnosis of compressive mononeuropathies like carpal tunnel syndrome (CTS), and on the most widely accepted guidelines, recommendations, quality measures, and electrodiagnostic classifications. A detailed, well-illustrated glossary explains the more commonly used terms in electrodiagnostic medicine (EDX). The book is primarily intended for residents and professionals in Neurology, as well as rehabilitation physicians and clinical neurophysiologists. The detailed descriptions of techniques and their practical use will also make the book an invaluable tool for novices and clinical neurophysiology technicians.
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    Part 1. Morphological basis and neurophysiological control -- Part 2. Endogenous and exogenous agents.
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    Symbols -- Acronyms & abbreviations -- Eponyms.
  • Epidemiology of vector-borne diseases / William K. Reisen -- Cockroaches (Blattaria) / Richard J. Brenner -- Lice (Phthiraptera) / Lance A. Durden -- True bugs (Hemiptera) ; Beetles (Coleoptera) / William L. Krinsky -- Fleas (Siphonaptera) / Lance A. Durden, Robert Traub -- Flies (Diptera) / Robert D. Hall, Reid R. Gerhardt -- Moth flies and sand flies (Psychodidae) / Louis C. Rutledge, Raj K. Gupta -- Biting midges (Ceratopogonidae) / Gary R. Mullen -- Black flies (Simuliidae) / Peter H. Adler, John W. McCreadie -- Mosquitoes (Culicidae) / Woodbridge A. Foster, Edward D. Walker -- Horse flies and deer flies (Tabanidae) / Bradley A. Mullens -- Muscid flies (Muscidae) / Roger D. Moon -- Tsetse flies (Glossinidae) / William L. Krinsky -- Myiasis (Muscoidea, Oestroidea) / E. Paul Catts, Gary R. Mullen -- Louse flies, keds, and related flies (Hippoboscoidea) / John E. Lloyd -- Moths and butterflies (Lepidoptera) / Gary R. Mullen -- Ants, wasps, and bees (Hymenoptera) / Roger D. Akre, Hal C. Reed -- Scorpions (Scorpiones) / Gary R. Mullen, Scott A. Stockwell -- Solpugids (Solifugae) ; Spiders (Araneae) / Gary R. Mullen -- Mites (Acari) / Gary R. Mullen, Barry M. OConnor -- Ticks (Ixodida) / Daniel E. Sonenshine, Robert S. Lane, William L. Nicholson.
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  • "Artificial Intelligence techniques have been successfully applied to the medical domain, and AI systems are being integrated into healthcare. AI systems can make providing healthcare more accurate, less expensive, more available, and more efficient. They are consistent and can be mass produced. This book includes a number of contributed chapters that detail the most recent advances and research efforts by world-wide experts in the field. The chapters follow the organization of the taxonomy; and offer a clear connection between chapters"--Provided by publisher.
  • Brought to you in a thorough yet accessible manner, the new edition of Medical Biochemistry gives access to all of the latest information on basic and clinically focused genetic and molecular biology. Featuring a team of contributors that includes investigators involved in cutting-edge research as well as experienced clinicians, this updated medical textbook offers a unique combination of both research and practice that's ideal for today's problem-based integrated courses. Relate biochemistry to everyday practice with the help of Clinical Boxes integrated into the text, and access in-depth coverage of important topics - including recent research in biochemistry - through Advanced Concept Boxes.Test your knowledge and improve retention with Active Learning Boxes at the conclusion of each chapter, and quickly review the most common lab tests performed with convenient Clinical Test Boxes.Effectively study the most updated information in biochemistry with the help of a dynamic, full-color design.Better understand the relationship between science and clinical practice with material organized by organ rather than system.
  • 2005 Springer Protocols
    Basic techniques in molecular biology / Ralph Rapley -- Probe design, production, and applications / Marilena Aquino de Muro -- Restriction enzymes: tools in clinical research / Gareth J.S. Jenkins -- Southern blotting as a diagnostic method / Bronwen Harvey and Pirkko Soundy -- Western blotting as a diagnostic method / Pirkko Soundy and Bronwen Harvey -- Principles and medical applications of the polymerase chain reaction / Bimal D. M. Theophilus -- Single strand conformation polymorphism (SSCP) analysis / Igor Vorechovsky -- Denaturing gradient gel electrophoresis (DGGE) / Jeroen H. Roelfsema and Dorien J.M. Peters -- Quantitative analysis of DNA sequences by PCR and solid phase sequencing / Anu Suomalainen and Ann-Christine Syvänen -- Introduction to capillary electrophoresis of DNA: biomedical applications / Beatriz Sanchez-Vega -- Mapping techniques / Simon G. Gregory -- Dideoxyfingerprinting for mutation detection / Ioannis Bossis, Antonios Voutetakis, and Constantine A. Stratakis -- Conformation sensitive gel electrophoresis / Marian Hill -- Amplification refractory mutation system and molecular diagnostics / Richard Kitching and Arun Seth -- Ligase chain reaction / Carla Osiowy -- Chemical cleavage of mismatch: theory and clinical applications / Neil V. Whittock and Louise Izatt -- The protein truncation test / Johan T. den Dunnen -- Linkage, allele sharing, and association / Mara Giordano -- Single nucleotide polymorphisms: technology and applications / Cyril Mamotte, Frank Christiansen, and Lyle J. Palmer -- cDNA microarrays / Philip G. Febbo -- Nucleic acid sequence-based amplification / Katherine Loens, D. Ursi, H. Goosens, and M. Ieven -- The oligonucleotide ligation assay / Faye A. Eggerding -- Quantitative taqman real-time PCR: diagnostic and scientific applications / Jörg Dötsch, Ellen Schoof, and Wolfgang Rascher -- Use of denaturing high-performance liquid chromatography in molecular medicine / Elizabeth L. Rugg and Gareth J. Magee -- Quantitative PCR / David Sugden -- Liquid chromatography-mass spectrometry of nucleic acids / Herbert Oberacher and Walther Parson -- Comparative genomic hybridization in clinical and medical research / Peng-Hui Wang, Yann-Jang Chen, and Chi-Hung Lin -- Bioinformatics tools for gene and protein sequence analysis / Bernd H.A. Rehm and Frank Reinecke -- In situ hybridization / Amanda D. Watters -- Enzyme-linked immunosorbent assay / William J. Jordan -- Protein therapeutics: mouse, humanized, and human antibodies / Benny K.C. Lo -- Karyotyping / Avery A. Sandberg, John F. Stone, and Zhong Chen -- Microsatellite analysis / Rachel E. Ibbotson and Anton E. Parker -- Analysis of chromosomal translocations / Andreas Hochhaus -- Differential display: theory and applications / Irina Gromova, Pavel Gromov, and Julio E. Celis -- Techniques for gene expression profiling / Mark P. Richards -- Capillary electrophoresis in clinical analysis / Margaret A. Jenkins and Sujiva Ratnaike -- Flow cytometry in the biomedical arena / James L. Weaver and Maryalice Stetler-Stevenson -- Immunocytochemistry / Patricia A. Fetsch -- Ribotyping in clinical microbiology / Patricia Severino and Sylvain Brisse -- Diagnostic applications of protein microarrays / Samir Hanash -- The human genome project / Rahul Chodhari and Eddie Chung -- Prenatal diagnosis of inborn errors of metabolism / Guy T.N. Besley -- Gene therapy: methods and application / Stella B. Somiari.
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    Chronologically documents two hundred and fifty medical milestones from 10,000 B.C. to modern times, including the history of separating conjoined twins, the discovery of viruses, and the Human Genome Project.
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    Complete list of all medical colleges, existing and extinct, in the United States, Canada and Philippine Islands, followed by a brief history of each; a list of medical colleges approved by the Council on Medical Education and Hospitals of the American Medical Association, revised to June 1, 1929-; a list of approved graduate medical schools and courses in the United States and a list of foreign medical colleges.
  • "This title provides a thorough understanding of the key decision making infrastructure of clinical practice and retains its emphasis on practice and principles of individualized medical decision making"--Provided by publisher.
  • Infrared imaging applied to dentistry -- Use of infrared imaging in veterinary medicine -- Standard procedures for infrared imaging in medicine -- Infrared detectors and detector arrays -- Infrared camera characterization -- Infrared camera and optics for medical applications -- sect. IV. Medical informatics. Hospital information systems: their function and state -- Computer-based patient records -- Overview of standards related to the emerging health care information infrastructure -- Introduction to informatics and nursing -- Non-AI decision making -- Medical informatics and biomedical emergencies: new training and simulation technologies for first responders -- sect. V. Biomedical sensors. Physical measurements -- Biopotential electrodes -- Electrochemical sensors -- Optical sensors -- Bioanalytic sensors -- Biological sensors for diagnostics -- sect. VI. Medical instruments and devices. Biopotential amplifiers -- Bioelectric impedance measurements -- Implantable cardiac pacemakers -- Medical instruments and devices used in the home -- Virtual instrumentation: applications in biomedical engineering -- sect. VII. Clinical engineering. Clinical engineering: evolution of a discipline -- Management and assessment of medical technology -- Risk factors, safety, and management of medical equipment -- Clinical engineering program indicators -- Quality of improvement and team building -- A standards primer for clinical engineers -- Regulatory and assessment agencies -- Applications of virtual instruments in health care -- sect. VIII. Ethical issues associated with the use of medical technology. Beneficence, nonmaleficence, and medical technology -- Ethical issues related to clinical research. Noninvasive arterial blood pressure and mechanics -- Cardiac output measurement -- External defibrillators -- Implantable defibrillators -- Implantable stimulators for neuromuscular control -- Respiration -- Mechanical ventilation -- Essentials of anesthesia delivery -- Electrosurgical devices -- Biomedical lasers -- Instrumentation for cell mechanics -- Blood glucose monitoring -- Atomic force microscopy: probing biomolecular interactions -- Parenteral infusion devices -- Clinical laboratory: separation and spectral methods -- Clinical laboratory: nonspectral methods and automation -- Noninvasive optical monitoring -- Sect. I. Biomedical signal analysis. Biomedical signals: origin and dynamic characteristics, frequency-domain analysis -- Digital biomedical signal acquisition and processing -- Compression of digital biomedical signals -- Time-frequency signal representations for biomedical signals -- Wavelet (time-scale) analysis in biomedical signal processing -- Higher-order spectral analysis -- Neural networks in biomedical signal processing -- complexity, scaling, and fractals in biomedical signals -- Future directions: biomedical signal processing and networked multimedia communications -- sect. II. Imaging. X-ray -- Computed tomography -- Magnetic resonance imaging -- Nuclear medicine -- Ultrasound -- Magnetic resonance microscopy -- Positron-emission tomography (PET) -- Electrical impedance tomography -- Medical applications of virtual reality technology -- Sect. III. Infrared imaging. Advances in medical infrared imaging -- The historical development of thermometry and thermal imaging in medicine -- Physiology of thermal signals -- Quantitative active dynamic thermal IR-imaging and thermal tomography in medical diagnostics -- Thermal texture maps (TTM): concept, theory, and applications -- IR imagers as fever monitoring devices: physics, physiology, and clinical accuracy -- Infrared imaging of the breast - an overview -- Functional infrared imaging of the breast: historical perspectives, current applications, and future considerations -- Detecting breast cancer from thermal infrared images by asymmetry analysis -- Advanced thermal image processing -- Biometrics: face recognition in thermal infrared -- Infrared imaging for tissue characterization and function -- Thermal imaging in diseases of the skeletal and neuromuscular systems -- Functional infrared imaging in clinical applications -- Thermal imaging in surgery --
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  • Presenting an overview of the basic principles of disaster management, this book describes the role of emergency medicine in disaster planning and mass casualty events. From disaster capacity to hazard risk score and vulnerability analysis, it addresses various aspects of disaster planning.
  • "The purpose of medical education is to benefit patients by improving the work of doctors. Patient centeredness is a centuries old concept in medicine, but there is still a long way to go before medical education can truly be said to be patient centered. Ensuring the centrality of the patient is a particular challenge during medical education, when students are still forming an identity as trainee doctors, and conservative attitudes towards medicine and education are common amongst medical teachers, making it hard to bring about improvements. How can teachers, policy makers, researchers and doctors bring about lasting change that will restore the patient to the heart of medical education? The authors, experienced medical educators, explore the role of the patient in medical education in terms of identity, power and location. Using innovative political, philosophical, cultural and literary critical frameworks that have previously never been applied so consistently to the field, the authors provide a fundamental reconceptualisation of medical teaching and learning, with an emphasis upon learning at the bedside and in the clinic. They offer a wealth of practical and conceptual insights into the three-way relationship between patients, students and teachers, setting out a radical and exciting approach to a medical education for the future." --Publisher description.
  • Basic radiation physics, chemistry, and biology -- Sources of radiation exposure -- Effects on genetic material -- Cancer induction and dose-response models -- Carcinogenesis of specific sites -- Deterministic effects of radiation -- Effects of radiation in combination with other agents -- Radiation exposure in utero -- Uranium, plutonium, and radium -- Attribution of radiation effects and probability of causation in a specific individual -- Perception of radiation and psychological risks -- Hormesis.
  • This document reviews the medical eligibility criteria for use of contraception, offering guidance on the safety of use of different methods for women and men with specific characteristics or known medical conditions. The recommendations are based on systematic reviews of available clinical and epidemiological research. It is a companion guideline to 'Selected Practice Recommendations for Contraceptive Use'. Together, these documents are intended to be used by policy-makers, programme managers, and the scientific community, to support national programmes in the preparation of service delivery guidelines.
  • Measuring and improving safety -- The evolution of the health care system -- Process change in health care institutions: top-down or bottom-up? -- The challenge of predicting in-hospital iatrogenic deaths -- Overview of hospital medicine -- Medical trainees and patient safety -- Matching levels of care with levels of illness -- General principles of medical emergency teams -- Potential sociological and political barriers to medical emergency team implementation -- Overview of various medical emergency team models -- Early goal-directed therapy -- Nurse-led medical emergency teams: a recipe for success in community hospitals -- ICU without walls: a New York City model -- Hospital size and location and the feasibility of the medical emergency team -- Medical emergency teams in teaching hospitals -- The nurse's perspective -- The hospital administrator's perspective -- Personnel resources for crisis response -- Equipment, medications, and supplies for a medical emergency team response -- Resident training and the medical emergency team -- Teaching organized crisis team functioning using human simulators -- Information systems considerations: integration of medical emergency team clinical indicators -- Evaluating complex system interventions in patient safety -- Integrating MET into a patient safety program -- Are medical emergency teams worth the cost?
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    Epidemic, encounter, and colonial promotion in Virginia -- Healing, medical authority, and moral degeneration in New England -- African testimony, dangerous communications, and colonial medical knowledge in the 1721 Boston -- Inoculation controversy -- Obeah, slave revolt, and plantation medicine in the British West Indies -- Drunkenness, syphilis, and history in Samson Occom's medical writing.
  • Medical English 2006
    Springer
  • Medical epidemiology 2005 (4th ed.)
    AccessMedicine
  • In addition to being essential for safe and effective patient care, medical equipment also has significant impact on the income and, thus, vitality of healthcare organizations. For this reason, its maintenance and management requires careful supervision by healthcare administrators, many of whom may not have the technical background to understand all of the relevant factors. This book presents the basic elements of medical equipment maintenance and management required of healthcare leaders responsible for managing or overseeing this function. It will enable these individuals to understand their professional responsibilities, as well as what they should expect from their supervised staff and how to measure and benchmark staff performance against equivalent performance levels at similar organizations. The book opens with a foundational summary of the laws, regulations, codes, and standards that are applicable to the maintenance and management of medical equipment in healthcare organizations. Next, the core functions of the team responsible for maintenance and management are described in sufficient detail for managers and overseers. Then the methods and measures for determining the effectiveness and efficiency of equipment maintenance and management are presented to allow performance management and benchmarking comparisons. The challenges and opportunities of managing healthcare organizations of different sizes, acuity levels, and geographical locations are discussed. Extensive bibliographic sources and material for further study are provided to assist students and healthcare leaders interested in acquiring more detailed knowledge.
  • Medical equipment and its life cycle -- Medical device risk, regulation and governance : an overview -- Approaches to equipment management : structures and systems -- Purchase and replacement : allocating priorities and managing resources -- Evaluating devices and technologies for replacement and equipping -- Equipment training for clinical and technical users -- Assessing maintenance and support needs -- Maintenance contract management -- Adverse incidents, investigations, control and monitoring -- Supporting research and development -- Disposal -- Sources of information for equipment management professionals -- Improving performance: quality, indicators, benchmarking and audit.
  • "This book arrives at a time of heightened concerns about patient safety in medical care and the overall responsibility assumed by health professionals. It begins by exploring experiences of error and harm in general, and it covers medical errors that can be attributed to system failures and errors in an individual's reasoning, subsequent decision-making, and execution of tasks in medical care. It focuses on how to detect, correct, and avoid errors and their sometimes disastrous consequences. The book concludes with an analysis of the contributions and expectations of physicians in tort litigation and legal decision-making"--Provided by publisher.
  • Introduction -- General concepts -- Medical services -- Medical devices -- Analysis -- Human factors -- Management errors -- Communications -- Drug delivery.
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    Error -- Rationalization -- Narcissism -- SCRAM : a case study -- Forgiveness -- Remedies -- The empathic disclosure of medical error -- Beyond errors, beyond narcissism.
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    An ethical foundation -- A theological foundation -- Ethical issues in heart failure -- Ethical issues in lung failure -- Ethical issues in kidney failure -- Ethical issues involving failure of eating and drinking -- Ethical issues in brain failure -- Ethical issues in mind failure -- Ethical issues involving cultural and religious beliefs -- Ethical issues in the neonatal period -- Ethical issues in children -- Ethical issues in the use of reproductive technology -- Ethical issues in pregnancy -- Ethical issues in organ transplantation -- The priesthood of believers.
  • Medical ethics manual. 2nd ed. 2009
    WMA, Scroll to bottom of page for download options.
    1. Principal Features of Medical Ethics -- 2. Physicians and Patients -- 3. Physicians and Society -- 4. Physicians and Colleagues -- 5. Medical Research -- 6. Conclusion.
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    Gene structure and function -- Chromosomes and cell division -- Common chromosome disorders -- Single-gene (Mendelian) inheritance -- Identifying genes for Mendelian diseases -- Polygenic inheritance and complex diseases -- Genes and population -- Genes and haemoglobin -- Genes and development -- Genes and cancer -- Genes and biochemistry -- Genes, drugs, and treatment -- Clinical skills and scenarios -- Applied clinical genetics -- Appendix 1: Medical school core curriculum in genetics -- Appendix 2: Teaching medical genetics to undergraduate medical students -- Glossary.
  • Genetic basis of conditions commonly seen in ORL practice / Friedmann D.R., Lalwani A.K -- Basic medical genetics for the otolaryngologist / Alford, R.L., Darilek, S.A -- Ordering genetic tests and interpreting the results / Deignan, J.L., Grody, W.W. -- Referring patients for a medical genetics consultation and genetic counseling / Sutton, V.R. -- Towards an etiologic diagnosis: assessing the patient with hearing loss / Lin, J., Oghalai, J.S. -- Nonsyndromic hereditary hearing loss / Alford, R.L. -- Hereditary hearing loss with thyroid abnormalities / Choi, B.Y. ... [et al.] -- Pigmentary anomalies and hearing loss / Toriello, H.V. -- Usher syndrome: hearing loss with vision loss / Friedman, T.B. ... [et al.] -- Genetic disorders with both hearing loss and cardiovascular abnormalities / Belmont, J.W. ... [et al.] -- Hearing loss disorders associated with renal disease / Kimberling, W.J., Borso, N., Smith, R.J. -- Multiple endocrine neoplasia: types 1 and 2 / Marsh, D.J., Gimm, O. -- Neurofibromatosis type 2 / Evans, D.G.R., Lloyd, S.K.W., Ramsden, R.T. -- Hereditary paragangliomas / Raygada, M., Pasini, B., Stratakis, C.A. -- Genetic causes of nonsyndromic cleft lip with or without cleft palate / Yuan, Q., Blanton, S.H., Hecht, J.T -- Chronic rhinosinusitis / Wang, X., Cutting, G.R. -- Otosclerosis / Ealy, M., Smith, R.J.H -- Genetics of vestibulopathies / Jen, J.C. -- Genetics of otitis media / Post, J.C. -- Gene therapy for head and neck cancer / Abuzeid, W.M., Li, D., O'Malley Jr., B.W.
  • Lynn B. Jorde, PhD; John C. Carey, MD; and Michael J. Bamshad, MD integrate recent developments with clinical practice and emphasize the central principles of genetics and their clinical applications. Now in full color, this edition provides you with the stunning visual clarity so important in this field. Get the very latest on hot topics like gene identification, cancer genetics, gene testing and gene therapy, common diseases, ethical and social issues, personalized medicine, and much more.
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    v. 1. Conception control.
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    "Diseases affecting the skin have tended to provoke a response of particular horror in society. With obvious and sometimes repellant outward signs of malady, they were often perceived to be highly contagious, as well as synonymous with immorality. Such connotations may have stemmed from the tell-tale buboes of syphilis, but the social stigma of disfigurement is something that still exists today. This collection of essays uses case studies to chart the medical history of skin from the eighteenth to the twentieth century." -- [Publisher-supplied data]
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  • pt. 2, 2004 Springer
  • Medical Imaging in Clinical Trials is a key text in understanding the methodology and the metrics that are required in the field of medical imaging. As the pharmaceutical, biotech and medical device industries continue to identify ways to improve and speed up product development, medical imaging plays a more significant role. Medical Imaging in Clinical Trials aims to educate and provide a hands-on text for those involved in clinical trials and either new to medical imaging and having to assimilate it into clinical trials or requiring to understand the key differences between clinical trial imaging and routine clinical imaging. It is targeted to those professionals involved in clinical trials at the clinical research site, pharmaceutical and medical device industries, and regulators. This is not the "how to image" book written for the radiologist or Radiological Technologist, but covers the critical aspects of clinical trial methodology that are important for these individuals to understand. This book addresses the ethics and radiation dosages of the different modalities, the end points commonly used for the different trial phases, the acquisition and analysis techniques, as well as the logistics management of medical imaging and the role of the central imaging lab or imaging core lab (ICL) which is now the standard requirement for clinical trials. Furthermore this text delves into the details of the major therapeutic areas where medical imaging plays a primary or secondary efficacy or safety end point.
  • "This book offers a selective review of key imaging modalities focusing on modalities with established clinical utilization. It provides a detailed overview of x-ray imaging and computed tomography, fundamental concepts in signal acquisition and processes, followed by an overview of functional MRI (fMRI) and chemical shift imaging. It also covers topics in Magnetic Resonance Microscopy, the physics of instrumentation and signal collection, and their application in clinical practice. The selection of topics provides readers with an appreciation of the depth and breadth of the field and the challenges ahead of the technical and clinical community of researchers and practitioners"--Provided by publisher.
  • "The book has two intentions. First, it assembles the latest research in the field of medical imaging technology in one place. Detailed descriptions of current state-of-the-art medical imaging systems (comprised of x-ray CT, MRI, ultrasound, and nuclear medicine) and data processing techniques are discussed. Information is provided that will give interested engineers and scientists a solid foundation from which to build with additional resources. Secondly, it exposes the reader to myriad applications that medical imaging technology has enabled"-- Provided by publisher.
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    Basic immunology. Introduction / Gabriel Virella. Cells and tissues involved in the immune response / Gabriel Virella. Major histocompatibility complex / Janardan P. Pandey. Immune response: antigens, lymphocytes, and accessory cells / Donna L. Farber, John W. Sleasman, and Gabriel Virella. Immunoglobulin structure / Gabriel Virella. Biosynthesis, metabolism, and biological properties of immunoglobulins / Gabriel Virella. Genetics of immunoglobulins / Janaradan P. Pandey. Antigen-antibody reactions / Gabriel Virella. Complement system / Robert J. Boackle. Lymphocyte ontogeny and membrane markers / Virginia M. Litwin. Cell-mediated immunity / Donna L. Farber and Gabriel Virella. Humoral immune response and its induction by active immunization / Gabriel Virella. Phagocytosis / Gabriel Virella. Infection and immunity / Gabriel Virella and Stephen Tomlinson -- Diagnostic immunology. Diagnostic immunology / Virginia M. Litwin and Gabriel Virella -- Clinical immunology. Tolerance and autoimmunity / George C. Tsokos and Gabriel Virella. Organ-specific autoimmune diseases / Gabriel Virella and George C. Tsokos. Systemic lupus erythematosus / George C. Tsokos. Rheumatoid arthritis / George C. Tsokos and Gabriel Virella. Hypersensitivity reactions / Gabriel Virella. Immunoglobulin e-mediated (immediate) hypersensitivity / Albert F. Finn, Jr. and Gabriel Virella. Immunohematology / Gabriel Virella and Armand Glassman. Immune complex diseases / Gabriel Virella and George C. Tsokos. Immune system modulators / Philip D. Hall and Gabriel Virella. Transplantation immunology / Justin D. Ellett, Gabriel Virella, and Kenneth D. Chavin. Tumor immunology / Deanne M.R. Lathers and Sebastiano Gattoni-Celli. Lymphocyte and plasma cell malignancies / Gabriel Virella -- Immunodeficiency diseases. Diagnosis of immunodeficiency diseases / John W. Sleasman and Gabriel Virella. Primary immunodeficiency diseases / John W. Sleasman and Gabriel Virella. AIDS and other acquired immunodeficiency diseases / John W. Sleasman and Gabriel Virella.
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  • Knowledge management, data mining, and text mining in medical informatics -- Mapping medical informatics research -- Bioinformatics challenges and opportunities -- Managing information security and privacy in health care data mining: state of the art -- Ethical and social challenges of electronic health information -- Medical concept representation -- Characterizing biomedical concept relationships: concept relationships as a pathway for knowledge creation and discovery -- Biomedical ontologies -- Information retrieval and digital libraries -- Modeling text retrieval in biomedicine -- Public access to anatomic images -- 3D medical informatics: information science in multiple dimensions -- Infectious disease informatics and outbreak detection -- Semantic interpretation for the biomedical research literature -- Semantic text parsing for patient records -- Identification of biological relationships from text documents -- Creating, modeling and visualizing metabolic networks: FCModeler and PathBinder for network modeling and creation -- Gene pathway text mining and visualization -- The genomic data mine -- Exploratory genomic data analysis -- Joint learning using multiple types of data and knowledge.
  • Over the years, medical informatics has matured into a true scientific discipline. Fundamental and applied aspects are now taught in various fields of health, including medicine, dentistry, pharmacy, nursing and public health. Medical informatics is also often included in the curricula of many other disciplines, including the life sciences, engineering and economics. Medical informatics is a complex and rapidly changing discipline. Relatively few books have been published on the subject, and they rapidly become obsolete. This book is the fruit of a collaborative effort between authors teaching medical informatics in France and others who are conducting research in this field. In addition, an international perspective was pursued, as reflected in the inclusion of various developments and actions in both the USA and Europe. This book is divided into 18 chapters, all of which include learning objectives, recommendations for further reading, exercises and bibliographic references.
  • Advances in medical infrared imaging / Nicholas A. Diakides ... [et al.] -- The historical development of thermometry and thermal imaging in medicine / Francis E. Ring and Bryan F. Jones -- Infrared detectors and detector arrays / Paul R. Norton ... [et al.] -- Infrared camera characterization / Joseph G. Pellegrino ... [et al.] -- Infrared camera and optics for medical applications / Michael W. Grenn ... [et al.] -- Physiology of thermal signals / David D. Pascoe, James B. Mercer, and Lois de Weerd -- Quantitative active dynamic thermal IR-imaging and thermal tomography in medical diagnostics / Antoni Nowakowski -- Dynamic thermal assessment / Michael Anbar -- Infrared imaging of the breast : a review / William C. Amalu ... [et al.] -- Functional infrared imaging of the breast: historical perspectives, current application, and future considerations / John R. Keyserlingk ... [et al.] -- Detecting breast cancer from thermal infrared images by asymmetry analysis / Hairong Qi, Phani Teja Kuruganti, and Wesley E. Snyder -- Advanced thermal image processing / Boguslaw Wiecek ... [et al.] -- Physiology- based face recognition in the thermal infrared spectrum / Pradeep Buddharaju and Ioannis Pavlidis -- Infrared imaging for functional monitoring of disease processes / Moinuddin Hassan ... [et al.] -- Biomedical applications of functional infrared imaging / Arcangelo Merla and Gian Luca Romani -- Fever mass screening tool for infectious diseases outbreak: integrated artificial intelligence with bio-statistical approach in thermogram analysis / E.Y.K. Ng and E.C. Klee -- Thermal imaging in diseases of the skeletal and neuromuscular systems / Francis E. Ring and Kurt Ammer -- Functional infrared imaging in the evaluation of complex regional pain syndrome, type I: current pathophysiological concepts, methodology, case studies, clinical implications / Timothy D. Conwell, James Giordano, and Steven J. Gulevich -- Thermal imaging in surgery / Paul Campbell and Roderick Thomas -- Infrared imaging applied to dentistry / Barton M. Gratt -- Use of infrared imaging in veterinariay medicine / Ram C. Purohit, Tracy A. Turner, and David D. Pascoe -- Standard procedures for infrared imaging in medicine / Kurt Ammer and Francis E. Ring -- Storage and retrieval of medical thermograms / Gerald Schaefer -- Ethical obligations in infrared imaging research and practice / James Giordano.
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    Basic concepts of medical instrumentation / Walter H. Olson -- Basic sensors and principles / Robert A. Peura and John G. Webster -- Amplifiers and signal processing / John G. Webster -- The origin of biopotentials / John W. Clark, Jr. -- Biopotential electrodes / Michael R. Neuman -- Biopotential amplifiers / Michael R. Neuman -- Blood pressure and sound / Robert A. Peura -- Measurement of flow and volume of blood / John G. Webster -- Measurements of the respiratory system / Frank P. Primiano, Jr. -- Chemical biosensors / Robert A. Peura -- Clinical laboratory instrumentation / Lawrence A. Wheeler -- Medical imaging systems / Melvin P. Siedband -- Therapeutic and prosthetic devices / Michael R. Neuman -- Electrical safety / Walter H. Olson.
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    The patient's story -- Interviewing as a clinical skill -- Respect, genuineness, and empathy -- Chief complaint and present illness -- Other active problems, past medical history, and family history -- The patient profile -- The sexual history -- Review of systems, physical examination, and closure -- The clinical narrative -- Communication in the office setting -- Pediatric and adolescent interviewing -- Interviewing the geriatric patient -- Cultural competence in the interview -- Difficult patient-clinician interactions -- Telling bad news -- Talking with patients about complementary and alternative medicine -- Ethics and the law -- Malpractice and the clinical interview -- Education and negotiation -- The medical interview at work.
  • The Medical Interview by Drs. Steven A. Cole and Julian Bird equips you to communicate effectively with your patients so you can provide optimal care! This best-selling, widely adopted resource presents a practical, systematic approach to honing your basic interviewing skills and managing common challenging communicating situations. Its Three-Function Approach - "Build the Relationship," "Assess and Understand," and Collaborative Management" offers straightforward tasks, behaviors, and skills that can be easily mastered, making this an ideal learning tool for beginners and a valuable reference for experienced healthcare professionals. Effectively meet a full range of communication challenges including language and cultural barriers, sexual issues, elderly patients, breaking bad news, and non-adherence.
  • 1. Introduction -- 2. Defining the rights to physician-assisted suicide -- 3. Glucksburg v. Compassion -- 4. A legal right to physician-assisted suicide -- 5. A moral right to physician assisted suicide -- 6. The concept of fetal rights -- 7. Maternal duties and fetal rights -- 8. The scope of the right to procreational autonomy -- 9. Possessors of the right to procreational autonomy -- 10. Medical futility and moral rights.
  • Using a case-based approach, Medical Leadership and Management uses internationally recognized competency frameworks to support knowledge acquisition and skills relevant to medical management and leadership. The text and supporting cases studies describe key medical management and leadership competencies, illustrating the theoretical and practical aspects of these competencies in the healthcare setting. With 23 years in clinical, teaching and health administration, Dr Geraldine MacCarrick has extensive knowledge of the education and training issues facing the medical profession. Despite lack of formal training, doctors worldwide are increasingly assuming greater leadership and management roles in healthcare. Effective medical leadership is recognized as essential for improving the performance of health services, enhancing the wellbeing of patients and the quality of outcomes. Medical Leadership and Management is of interest to all medical educators interested in supporting their students to acquire leadership and management skills in preparation for graduation and beyond.
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    The Birth of medical regulation in America -- The Roots of the Federation of State Medical Boards -- Beginnings, growth and challenges, 1912-1929 -- Stasis and resurgence, 1930-1959 -- Walter Bierring and the Federation's early leadership -- The Push for public accountability, 1961-1979 -- The Modern Federation emerges, 1980-2001 -- A New millennium, a second century.
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    Arrivals -- Student days : the shared experience of survival -- Joseph Lister and the teaching of surgery -- First steps : the first five years after qualification -- Jex-Blake's women : education and careers -- Varieties of practice -- Listerism in practice -- Lister's men abroad : settlers -- Lister's men abroad : imperialists, missionaries and enclaves -- Last days.
  • Insuring the practice of medicine / Mark Gorney and Richard E. Anderson -- What every doctor should know about litigation : a primer on how to win medical malpractice lawsuits / Fred J. Hiestand -- Risk reduction from a plaintiff attorney's perspective / David Wm. Horan -- The physician as a witness / Joel A. Mattison -- The judicial process : discovery and deposition / Jonathan I. Epstein -- Communication and patient safety / Mark Gorney -- E-medicine in the physician's office / Edward Fotsch -- Risk management for the family physician / Malcolm H. Weiss -- Emergency medicine / Michael Jay Bresler -- Anesthesiology / Ann S. Lofsky -- Malpractice and medical practice : obstetrics and gynecology / Jack M. Schneider -- Breast cancer litigation / Richard E. Anderson and David B. Troxel -- Pap smear litigation / David B. Troxel -- Medical liability in plastic and reconstructive surgery / Mark Gorney -- The case for legal reform / Richard E. Anderson -- Health policy review : medical malpractice / David M. Studdert, Michelle M. Mello, and Troyen A. Brennan -- New directions in medical liability reform / William M. Sage.
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    Medical malpractice and tort reform in the USA -- Avoiding problems with Qui Tam, HIPPA, and other disciplinary actions -- Maritime medical malpractice -- Defensive moves and strategies to avoid medical malpractice suits in primary medical care and specialist practice -- Proactive strategies to reduce malpractice risks in primary care and surgical practice -- Proactive strategies to reduce malpractice risks in psychiatry -- What you must know about managed care snares and punitive damages -- How to avert or deal with a potential medical malpractice suit : strategies for averting medical malpractice -- What to do and not to do in a pending or ongoing medical malpractice suit -- Alterante dispute resolution as an alternative to medical malpractice litigation : alternate dispute resolution, mediationm and other options for the defendant physician -- Caveats on testifying physicians : attorney relationships -- How physicians can be investigated prior to trial : investigating the medical expert witness -- Overview of a medical malpractice trial -- Introducing the physician to legal testimony : preparing the defendant physician for testimony -- A trial judge's advice to testifying physicians on enhancing credibility in court -- Medical malpractice terms and definitions for the testifying physician -- Medical malpractice terms and tips for the testifying physician -- How to prepare for and handle your deposition : deposition preparation for the physician -- How to manage attorney abuse -- Ten examples on the Daubert impact on physician testimony -- The use of evidence- based medicine to fend off a Daubert and cross examination challenge of your medical opinion[s] -- Resource of legal theories, themes, and analogies for the medical expert witness -- Example of translating for the jury; medicalese into understandable English -- Lessons from my expert testimony mistakes -- Critiques and golden nuggets for physician defendants and medical expert witnesses -- Medical expert witness rewards.
  • Reduce your risk of costly litigation! Written in easy-to-understand language by a team of medical doctors who are also attorneys at law, this handbook addresses the issues surrounding the growing incidence of medical malpractice. It examines the scenarios that can result in a malpractice suit, the best actions to take during the course of litigation, and the most effective ways to minimize your legal liabilities. Access the expert guidance of top professionals across medical and legal fields in an easy-to-read format. Review the legal aspects of nearly every medical topic that impacts health care professionals. Quickly see how to minimize your legal liabilities with the aid of "Golden Rule" boxes. Understand the different types of malpractice suits and the physician's position and defense in each. See how concepts apply to specific scenarios through abundant case studies. Explore specific legal considerations for each medical specialty.
  • 1. Introduction -- 2. Pathogenesis of glaucoma -- 3. Diagnosing glaucoma -- 4. Medical management of glaucoma.
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  • The role and responsibility of the medical consultant / Geno J. Merli, Howard H. Weitz -- Preoperative assessment for the healthy patient / Barry S. Ziring -- Antimicrobial prophylaxis : prevention of postoperative infections / Robert E. Measley, Jr. -- Selected medical challenges of anesthesia / Robert F. Atkins -- Prophylaxis for deep vein thrombosis and pulmonary embolism in the surgical patient / Geno J. Merli -- Perioperative evaluation of patients with hematologic disorders / Frederick M. Fellin -- Noncardiac surgery in the patient with cardiovascular disease : preoperative evaluation and perioperative care / Howard H. Weitz -- Perioperative assessment and management of patients with pulmonary diseases / Gregory C. Kane, Bartolome R. Celli -- Gastrointestinal complications in the postoperative period / John A. Evans, David G. Forcione, Lawrence S. Friedman -- Management of the surgical patient with liver disease / Jacqueline G. O'Leary, Lawrence S. Friedman -- Bariatric surgery : preoperative evaluation and postoperative care / James Fink -- Perioperative management of endocrine disorders / Kevin Furlong, Intekhab Ahmed, Serge Jabbour -- Perioperative management of the ophthalmologic patient / Marvin E. Gozum -- Nonobstetric surgery in the pregnant patient / Barbara Knight, Janine V. Kyrillos -- The patient with substance abuse going to surgery / Elizabeth Teperov -- Perioperative assessment and management of the surgical patient with neurologic problems / Rodney D. Bell, Geno J. Merli -- Perioperative care of the elderly patient / Michael F. Lubin -- Surgery in the patient with kidney disease / Brenda Hoffman, Tracy McGowan -- Perioperative management of the patient with arthritis or systemic autoimmune disease / Brian F. Mandell -- Perioperative care of the patient with psychiatric illness / Jenny Y. Wang, Daniel K. Holleran, Barry S. Ziring -- Managing medication in the perioperative period / Walter K. Kraft, Gretchen Diemer.
  • This book is a comprehensive pulmonary and thoracic reference that takes a practical approach to the diagnosis, workup and care of the thoracic surgery patient. It is geared towards pulmonary and critical care physicians and their trainees as well as all other specialties with whom thoracic surgeons consult and interact. It outlines the principles for understanding the underlying disease entities as well as the clinical implications and complications of surgery, and interprets key surgical concepts such as correlative and functional anatomy for non-surgeons. Contributions from todays authorities, at-a-glance detailed key information, as well as summary bullets ; and a multidisciplinary perspective, combine to offer essential guidance for confident patient management.
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    v. 1-3 include biographical sketches of 47 medical doctors who have contributed to the progress of the science and art of medicine and who fit the definition of maverick as an independent individual who refuses to conform to his group. The date range is from 460 B.C.E. to the 21th century.
  • Medical microbiology 2005
    Thieme Book
  • Microbiology and medicine -- Morphology and nature of micro-organisms -- Classification, identification and typing of micro-organisms -- Bacterial growth, physiology and death -- Antimicrobial agents -- Bacterial genetics -- Virus-cell interactions -- Immunological principles: Antigens and antigen recognition -- Innate and acquired immunity -- Immunity in viral infections -- Parasitic infections: Pathogenesis and immunity -- Immunity in bacterial infections -- Bacterial pathogenicity -- The natural history of infection -- Staphylococcus: Skin infections; osteomyelitis; bloodstream infection; food poisoning; foreign body infections; MRSA -- Streptococcus and enterococcus: Pharyngitis; scarlet fever; skin and soft tissue infections; streptococcal toxic shock syndrome; pneumonia; meningitis; urinary tract infections; rheumatic fever; post-streptococcal glomerulonephritis -- Coryneform bacteria, listeria and erysipelothrix: Diphtheria; listeriosis; erysipeloid -- Mycobacterium: Tuberculosis; leprosy -- Environmental mycobacteria: Opportunist disease -- Actinomyces, nocardia and tropheryma: Actinomycosis; nocardiasis; Whipple's disease -- Bacillus: Anthrax; food poisoning -- Clostridium: Gas gangrene; tetanus; food poisoning; pseudomembranous colitis -- Neisseria and moraxella: Meningitis; septicaemia; gonorrhoea; respiratory infections -- Salmonella: Food poisoning; enteric fever -- Shigella: Bacillary dysentery -- Escherichia: Urinary tract infection; travellers' diarrhoea; haemorrhagic colitis; haemolytic uraemic syndrome -- Klebsiella, enterobacter, proteus and other enterobacteria: Pneumonia; urinary tract infection; opportunist infection -- Pseudomonads and non-fermenters: Opportunist infection; cystic fibrosis; melioidosis -- Campylobacter and helicobacter: Enteritis; polyneuropathy; gastritis; peptic ulcer disease; gastric cancer -- Vibrio, mobiluncus, gardnerella and spirillum: Cholera; vaginosis; rat bite fever -- Haemophilus: Respiratory infections; meningitis; chancroid -- Bordetella: Whooping cough -- Legionella: Legionnaires' disease; Pontiac fever -- Brucella, bartonella and streptobacillus: Brucellosis; Oroya fever; trench fever; cat scratch disease; bacillary angiomatosis; rat bite fever -- Yersinia, pasteurella and francisella: Plague; pseudotuberculosis; mesenteric adenitis; pasteurellosis; tularaemia -- Non-sporing anaerobes: Wound infection; periodontal disease; abscess; normal flora -- Treponema and borrelia: Syphilis; yaws; relapsing fever; Lyme disease -- Leptospira: Leptospirosis; Weil's disease -- Chlamydia: Genital and ocular infections; infertility; atypical pneumonia -- Rickettsia, orientia, ehrlichia, anaplasma and coxiella: Typhus; spotted fevers; scrub typhus; ehrlichioses; Q fever -- Mycoplasmas: Respiratory and genital tract infections -- Adenoviruses: Respiratory disease; conjunctivitis; gut infections -- Herpesviruses: Herpes simplex; varicella and zoster; infectious mononucleosis; B cell lymphomas; cytomegalovirus disease; exanthem subitum; Kaposi's sarcoma; herpes B -- Poxviruses: Smallpox; molluscum contagiosum; parapoxvirus infections -- Papillomaviruses and polyomaviruses: Warts: warts and cancers; polyomavirus associated nephropathy; progressive multifocal leuco-encephalopathy -- Hepadnaviruses: Hepatitis B virus infection; hepatitis delta virus infection -- Parvoviruses: B19 infection; erythema infectiosum -- Picornaviruses: Meningitis; paralysis; rashes; intercostal myositis; myocarditis; infectious hepatitis; common cold -- Orthomyxoviruses: Influenza -- Paramyxoviruses: Respiratory infections; mumps; measles; Hendra/Nipah disease -- Arboviruses: alphaviruses, flaviviruses and bunyaviruses: Encephalitis; yellow fever; dengue; haemorrhagic fever; miscellaneous tropical fevers; undifferentiated fever -- Hepaciviruses and hepeviruses: Hepatitis C and E viruses; non-A, non-B hepatitis -- Arenaviruses and filoviruses: Viral haemorrhagic fevers -- Reoviruses: Gastroenteritis -- Retroviruses: Acquired immune deficiency syndrome; HTLV-1 -- Caliciviruses and astroviruses: Diarrhoeal disease -- Coronaviruses -- Rhabdoviruses -- Togaviruses: Rubella -- Prion diseases (transmissible spongiform encephalopathies): Creutzfeldt-Jakob disease; Gerstmann-Sträussler-Scheinker syndrome; fatal familial insomnia; iatrogenic Creutzfeldt-Jakob disease; kuru; variant Creutzfeldt-Jakob disease; bovine spongiform encephalopathy; scrapie-- Fungi: Superficial, subcutaneous and systemic mycoses -- Protozoa: Malaria; toxoplasmosis; cryptosporidiosis; amoebiasis; trypanosomiasis; leishmaniasis; giardiasis; trichomoniasis -- Helminths: Intestinal worm infections; filariasis; schistosomiasis; hydatid disease -- Arthropods: Arthropod-borne diseases; ectoparasitic infections; allergy -- Infective syndromes -- Diagnostic procedures -- Strategy of antimicrobial chemotherapy -- Epidemiology and control of community infections -- Hospital infection -- Immunization.
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  • Quickly learn the microbiology fundamentals you need to know with this 7th Edition, by Dr. Patrick R. Murray, Dr. Ken S. Rosenthal, and Dr. Michael A. Pfaller. Newly reorganized to correspond with integrated curricula and changing study habits, this practical and manageable text is clearly written and easy to use, presenting clinically relevant information about microbes and their diseases in a succinct and engaging manner. Learn the most up-to-date and relevant information in medical microbiology. Study efficiently thanks to a reorganized format that places review chapters at the beginning of each section and review questions at the end of each chapter. Focus on clinical relevance with new interactive case presentations to introduce each of the microbial pathogens that illustrate the epidemiology, diagnosis, and treatment of infectious diseases. Visualize the clinical presentations of infections with new and updated clinical photographs, images, and illustrations.
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    Overview of nutrition assessment in clinical care / Lisa Hark, Darwin Deen, and Alix Pruzansky -- Vitamins, minerals, and dietary supplements / Jeremy Brauer, Elizabeth Horvitz, and John Swaney -- Nutrition in pregnancy and lactation / Lisa Hark, Catherine Sullivan, and Darwin Deen -- Infants, children, and adolescents / Elizabeth B. Rappaport, Jennifer Thorpe, and Andrew M. Tershakovec -- Older adults / Jane V. White and Ronald H. Lands -- Cardiovascular disease / Jo Ann S. Carson and Scott M. Grundy -- Gastrointestinal disease / Gary R. Lichtenstein, Emily Gelsomin, and Julie Vanderpool -- Endocrine disease : diabetes mellitus / Marion J. Franz -- Pulmonary disease / Jessica Dine, Jennifer Williams, and Horace M. DeLisser -- Renal disease / Jean Stover and Gail Morrison -- Cancer prevention and treatment / Tamara Bockow and Satya Jonnalagadda -- Enteral nutrition support / Judith Fish and Douglas Seidner -- Parenteral nutrition support / Laura Matarese, Robert DeChicco, and Ezra Steiger.
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    Clinical anatomy and physiology of the auditory and vestibular systems / Mohamed Hamid and Kianoush Sheykholeslami -- Genetics of hearing loss / Arti Pandya and Walter E. Nance -- Ion homeostasis and inner ear disease / Dennis R. Trune -- Regenerative medicine for inner ear disease / John V. Brigande -- Clinical approach to patients with auditory and vestibular disorders / Mohamed Hamid and Aristides Sismanis -- Peripheral auditory and vestibular disorders / Mohamed Hamid and Aristides Sismanis -- Central vestibular disorders / Marc Friedman, Franck G. Skobieranda, and Mohamed Hamid -- Vestibular and balance rehabilitation / Mohamed Hamid and Hesham M. Samy -- Autoimmune otologic disorders / Aristides Sismanis and Mohamed Hamid -- Eustachian tube function and dysfunction / Dennis S. Poe -- Tinnitus: evaluation and management / Aristides Sismanis and Jack A. Vernon -- Diagnosis and medical management of disorders of the facial nerve / Harvey M. Tucker -- Cochlear implants / Aristides Sismanis and M. Suzanne Hasenstab -- Surgery for vertigo / Aristides Sismanis.
  • Principles of pharmacology and mechanisms of drug action -- Principles of pharmacology and mechanisms of drug action -- Drug discovery, safety and efficacy -- Neurotransmission and the peripheral autonomic nervous system -- Ischaemic heart disease -- Systemic and pulmonary hypertension -- Heart failure -- Cardiac arrhythmias -- Cerebrovascular disease and dementia -- Peripheral vascular disease -- Haemostasis -- Asthma and chronic obstructive pulmonary disease -- Respiratory disorders : cough, respiratory stimulants, cystic fibrosis and neonatal respiratory distress syndrome -- Diuretics -- Disorders of micturition -- Erectile dysfunction -- General anaesthetics -- Local anaesthetics -- Opioid analgesics and the management of pain -- Anxiolytics, sedatives and hypnotics -- The major psychotic disorders : schizophrenia and mania -- Depression, attention deficit hyperactivity disorder and narcolepsy -- Epilepsy -- Extrapyramidal movement disorders and spasticity -- Other neurological disorders : multiple sclerosis, motor neuron disease and Guillain - Barre syndrome -- Migraine and other headaches -- The neuromuscular junction and neuromuscular blockade -- Myasthenia gravis -- Non-steroidal anti-inflammatory drugs -- Rheumatoid arthritis, other inflammatory arthritides and osteoarthritis -- Hyperuricaemia and gout -- Nausea and vomiting -- Dyspepsia and peptic ulcer disease -- Inflammatory bowel disease -- Constipation, diarrhoea and irritable bowel syndrome -- Liver disease -- Obesity -- The immune response and immunosuppressant drugs -- Antihistamines and allergic disease -- Diabetes mellitus -- The thyroid and control of metabolic rate -- Calcium metabolism and metabolic bone disease -- Pituitary and hypothalamic hormones -- Corticosteroids (glucocorticoids and mineralocorticoids) -- Female reproduction -- Androgens, anti-androgens and anabolic steroids -- Anaemia and haematopoietic colony-stimulating factors -- Lipid disorders -- Skin disorders -- The eye -- Chemotherapy of infections -- Chemotherapy of malignancy -- Drug toxicity and overdose -- Substance abuse and dependence -- Prescribing, adherence and information about medicines -- Drug therapy in special situations.
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    Traditional medicines -- Modern medicine -- Disease -- Diagnosis -- Drug -- Trial -- Treatment -- Prevention -- Iatroethics -- Science or technology, craft or service?
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    Section I: Introduction -- Foundations of physiology / Emile L. Boulpaep and Walter F. Boron -- Section II: Physiology of cells and molecules / Functional organization of the cell / Michael J. Caplan -- Signal transduction / Lloyd Cantley -- Regulation of gene expression / Peter Igarashi -- Transport of solutes and water / Peter S. Aronson, Walter F. Boron, and Emile L. Boulpaep -- Electrophysiology of the cell membrane / Edward G. Moczydlowski -- Electrical excitability and action potentials / Edward G. Moczydlowski -- Synaptic transmission and the neuromuscular junction / Edward G. Moczydlowski -- Cellular physiology of skeletal, cardiac, and smooth muscle / Edward G. Moczydlowski and Michael Apkon -- Section III: The nervous system -- Organization of the nervous system / Bruce R. Ransom -- The neuronal microenvironment / Bruce R. Ransom -- Physiology of neurons / Barry W. Connors -- Synaptic transmission in the nervous system / Barry W. Connors -- The autonomic nervous system / George B. Richerson -- Sensory transduction / Barry W. Connors -- Circuits of the central nervous system / Barry W. Connors -- Section IV: The cardiovascular system -- Organization of the cardiovascular system / Emile L. Boulpaep -- Blood / Emile L. Boulpaep -- Arteries and veins / Emile L. Boulpaep -- The microcirculation / Emile L. Boulpaep -- Cardiac electrophysiology and the electrocardiogram / W. Jonathan Lederer -- The heart as a pump / Emile L. Boulpaep -- Regulation of arterial pressure and cardiac output / Emile L. Boulpaep -- Special circulations / Steven S. Segal -- Integrated control of the cardiovascular system / Emile L. Boulpaep -- Section V: The respiratory system -- Organization of the respiratory system / Walter F. Boron -- Mechanics of ventilation / Walter F. Boron -- Acid-base physiology / Walter F. Boron -- Transport of oxygen and carbon dioxide in the blood / Walter F. Boron -- Gas exchange in the lungs / Walter F. Boron -- Ventilation and perfusion of the lungs / Walter F. Boron -- Control of ventilation / George B. Richerson and Walter F. Boron -- Section VI: The urinary system -- Organization of the urinary system / Gerhard Giebisch and Erich Windhager -- Glomerular filtration and renal blood flow / Gerhard Giebisch and Erich Windhager -- Transport of sodium and chloride / Gerhard Giebisch and Erich Windhager -- Transport of urea, glucose, phosphate, calcium, magnesium, and organic solutes / Gerhard Giebisch and Erich Windhager -- Transport of potassium / Gerhard Giebisch and Erich Windhager -- Urine concentration and dilution / Gerhard Giebisch and Erich Windhager -- Transport of acids and bases / Gerhard Giebisch and Erich Windhager -- Integration of salt and water balance / Gerhard Giebisch and Erich Windhager -- Section VII: The gastrointestinal system -- Organization of the gastrointestinal system / Henry J. Binder -- Gastric function / Henry J. Binder -- Pancreatic and salivary glands / Christopher R. Marino and Fred S. Gorelick -- Intestinal fluid and electrolyte movement / Henry J. Binder -- Nutrient digestion and absorption / Henry J. Binder and Adrian Reuben -- Hepatobiliary function / Frederick J. Suchy -- Section VIII: The endocrine system -- Organization of endocrine control / Eugene J. Barrett -- Endocrine regulation of growth and body mass / Eugene J. Barrett -- The thyroid gland / Eugene J. Barrett -- The adrenal gland / Eugene J. Barrett -- The endocrine pancreas / Eugene J. Barrett -- The parathyroid glands and vitamin D / Eugene J. Barrett and Paula Barrett -- Section IX: The reproductive system -- Sexual differentiation / Ervin E. Jones -- The male reproductive system / Ervin E. Jones -- The female reproductive system / Ervin E. Jones -- Fertilization, pregnancy, and lactation / Ervin E. Jones -- Fetal and neonatal physiology / Ervin E. Jones -- Section X: Physiology of everyday life -- Metabolism / Gerald I. Shulman and Kitt Falk Petersen -- Regulation of body temperature / John Stitt -- Exercise physiology and sports science / Steven S. Segal -- Environmental physiology / Arthur DuBois -- The physiology of aging / Edward J. Masoro.
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  • Medical Physiology, in its updated 2nd edition, firmly relates molecular and cellular biology to the study of human physiology and disease. Drs. Walter Boron and Emile Boulpaep and a team of leading physiologists present practical, accurate coverage emphasizing the clinical implications of the material. Each chapter explains the principles and organization of each body system, while more than 1400 high-quality, full-color line drawings and prominently featured clinical examples clarify every concept. This exceptionally detailed and comprehensive guide to physiology is ideal for a rich, straightforward, state-of-the-art understanding of this essential subject.
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    Expecting the unexpected : health information technology and medical professionalism / David Blumenthal -- Quality regulation in the information age : challenges for medical professionalism / Kristen Madison and Mark Hall -- The "information Rx" / Nancy Tomes -- When new is old : professional medical liability in the information age / Sara Rosenbaum and Michael W. Painter -- Patient data : professionalism, property, and policy / Marc Rodwin -- The impact of information technology on organ donation : private values in a public world / Sheila Rothman, Natassia Rozario, and David Rothman -- Changing the rules : the impact of information technology on contemporary maternity practice / Eugene Declercq -- A profession of IT's own : the rise of health information professionals in American health care / Mark C. Suchman and Matthew D. Dimick.
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  • Medical Radiation Dosimetry: Theory of Charged Particle Collision Energy Loss provides a uniquely required advanced, comprehensive and definitive theoretical description of the physics of charged particle collision energy loss and the role that it plays in the clinical radiation dosimetry resulting from exposure to ionising radiation. Medical Radiation Dosimetry: Theory of Charged Particle Collision Energy Loss is both an advanced mathematical and physics treatise and an essential reference volume for the medical physics graduate student and the medical radiation physicist working in the field of clinical and research radiation dosimetry. It will assist both audiences in both the understanding of the genesis of the numerical data provided in multiple technical reports and publications, and of the limitations of these data.
  • This book, written by members of the core faculty responsible for European courses on Medical Response to Major Incidents (MRMI), is a practical guide for all medical staff on how to respond to a wide range of disaster scenarios. The entire spectrum of knowledge is covered, from command and coordination through to the management of individual casualties. Central importance is attached to the key component of decision making by explaining what needs to be done for patients in particular situations and the required order and timing of treatment measures. Simplified methods receive due attention, as it is often necessary for medical staff to administer primary treatment outside of their own specialty. This book will prove an invaluable aid to all who may be involved in the response to major accidents and disasters, including medical and nursing students, ambulance crew, and military personnel as well as medical specialists.
  • Chemical nerve agents / Daniel C. Keyes -- Vesicating agents including mustard and Lewisite / Stacey L. Hail and Daniel C. Keyes -- Cyanide / Rebeca Gracia -- Phosgene and toxic gases / Melissa L. Givens -- Incapacitating agents: BZ, calmative agents, and riot control agents / John Gomez and Yedidia Bentur -- Anthrax / Anthony J. Carbone -- Plague / Anthony J. Carbone -- Smallpox / Lisa Rotz, Inger Damon, and Joanne Cono -- Viral hemorrhagic fevers / Erik J. Won and Anthony J. Carbone -- Lesser known biological agents and potential threats / Teriggi J. Ciccone and Seric S. Cusick -- Botulinum: the most toxic substance known / Robert Abar Timmons and Anthony J. Carbone -- Toxins / Sophia Dyer and Stephen Traub -- Types of radiation: basic theory explained for the nonphysicist / Greene Shepherd -- Detection of nuclear radiation / Keith Edsall and Daniel C. Keyes -- Personal protection and decontamination for radiation emergencies / Keith Edsall and Daniel C. Keyes -- Treatment of radiation exposure and contamination / Keith Edsall and Daniel C. Keyes -- Radiation dispersal devices, dirty bombs, and nonconventional radiation exposure / Madison Patrick, Keith Edsall, and Daniel C. Keyes -- Detonation of a nuclear device / Cham E. Dallas -- Nuclear power plant disasters / Wilfredo Rivera -- Types of explosions and explosive injuries defined / Adam Miller and Richard Linsky -- Structure collapse, extrication, crush syndrome, and rhabdomyolysis / Adam H. Miller -- Introduction to all-hazards preparedness and planning for terrorism / Adam H. Miller ... [et al.] -- Scene preparedness / Marc Eckstein and Ray Fowler -- Hospital preparedness / Kathy J. Rinnert and Daniel C. Keyes -- Community public health preparedness / Scott F. Wetterhall, and Darren F. Collins -- Mass gathering preparedness / Carl Menckhoff, and Michael Shaw -- Federal, state, regional, and local resource access and utilization / David W. Gruber -- Personal protective equipment / Joshua G. Schier and Robert S. Hoffman -- All-hazards approach to decontamination / Richard N. Bradley -- Detection, prediction, and surveillance / Warren L. Whitlock and Gay Dews Thompson -- Health care facilities and interagency communication during terrorism / Raymond L. Fowler ... [et al.] -- Media and communications preparedness for terrorist events / Raymond L. Fowler, Paul E. Pepe, Paul E. Moore -- Exercises and educational courses in terrorism preparedness / Myra M. Socher and Edwin K. Leap -- Technology applications in preparedness training / Timothy D. Peterson -- Strategic response to explosive and traumatic terrorism / Brian A. Krakover -- The forensic evaluation of gunshot wounds associated with a terrorist event / William S. Smock -- Homeland security / F. Marion Cain III and Gary L. Holt -- The role of military medicine in civilian disaster response / Brian A. Krakover -- Law enforcement related agencies / William Fabbri and Nelson Tang -- Psychological impact of terrorism / Gregory Luke Larkin, Jay Woody, and Cynthia Claassen -- Being a child in the midst of terrorism / Richard Aghababian ... [et al.] -- Agricultural terrorism and its implication on the health care system / Timothy Rupp and Shane Zatkalik -- Mass fatality incidents / Lynn Roppolo and Kathy Rinnert -- Cyberterrorism / Brian Krakover.
  • Medical retina 2005-
    Springer
    2007 Springer
    2010 Springer
    The Medical retina volumes of the series Essentials in ophthalmology provide concise updates on relevant and challenging topics in medical retina including the major advances in medical retina that have been made because of advances in ophthalmic imaging technology.
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  • An integrated approach to teaching basic sciences and clinical medicine has meant that medical students have been driven to a range of basic science textbooks to find relevant information. Medical Sciences is designed to do the integration for you. In just one book, the diverse branches of medical science are synthesised into the appropriate systems of the human body, making this an invaluable aid to approaching the basics of medicine within in a clinical context. Highly illustrated with clear, full-colour line drawings and colour photos. Information boxes throughout, giving more specific detail of research findings, drug mechanisms, etc. Clinical boxes throughout, demonstrating the clinical relevance of the science. Interactive features of the StudentConsult e-book (PIN access in your print copy) 5 slideshows 34 test yourself 4 slideshow test yourself 3 hotspots 2 guided tours 6 slidelines 435 MCQs (end-of-chapter quizzes and Assessment chapter in e-book)
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  • Medical secrets. 5th ed. 2012
    ScienceDirect
    2012 ClinicalKey
    Medical ethics / William L. Allen -- General medicine and ambulatory care / Mary P. Harward -- Medical consultation / Eric I. Rosenberg -- Cardiology / Gabriel Habib, Sr -- Vascular medicine / Timothy R. S. Harward -- Pulmonary medicine / Adriano R. Tonelli and Eloise Harman -- Gastroenterology / Rhonda A. Cole and Dang M. Nguyen -- Nephrology / Sharma S. Prabhakar -- Acid-base and electrolytes / Sharma S. Prabhakar -- Rheumatology / Roger Kornu ... [et al.] -- Allergy and immunology / Roger D. Rossen and Holly H. Birdsall -- Infectious diseases / Harrinarine Madhosingh and Frederick S. Southwick -- Aids and HIV infection / Joseph Caperna, Amy M. Sitapati, and Alfredo Tiu -- Hematology / Damian Silbermins and Ara D. Metjian -- Oncology / Teresa G. Hayes -- Endocrinology / Susan E. Spratt and Whitney W. Woodmansee -- Neurology / David B. Sommer -- Geriatrics / John Meuleman and Henrique Elias Kallas -- Palliative medicine / Leslye C. Penneypacker.
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    Types of data -- Data entry -- Error checking and outliers -- Displaying data graphically -- Describing data : the 'average' -- Describing data : the 'spread' -- Theoretical distributions : the normal distribution -- Theoretical distributions : other distributions -- Transformations -- Sampling and sampling distributions -- Confidence intervals -- Study design I -- Study design II -- Clinical trials -- Cohort studies -- Case-control studies -- Hypothesis testing -- Errors in hypothesis testing -- Numerical data : a single group -- Numerical data : two related groups -- Numerical data : two unrelated groups -- Numerical data : more than two groups -- Categorical data : a single proportion -- Categorical data : two proportions -- Categorical data : more than two categories -- Correlation -- The theory of linear regression -- Performing a linear regression analysis -- Multiple linear regression -- Binary outcomes and logistic regression -- Rates and Poisson regression -- Generalized linear models -- Explanatory variables in statistical models -- Issues in statistical modelling -- Checking assumptions -- Sample size calculations -- Presenting results -- Diagnostic tools -- Assessing agreement -- Evidence-based medicine -- Methods for clustered data -- Regression methods for clustered data -- Systematic reviews and meta-analysis -- Survival analysis -- Bayesian methods.
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    Concepts of medical terminology -- Suffixes -- Prefixes -- Cells, tissues, and organs -- Body structure -- Disease -- Diagnosis and treatment. Surgery -- Drugs -- Circulation : the cardiovascular and lymphatic systems -- Blood and immunity -- The respiratory system -- The digestive system -- The urinary system -- The male reproductive system -- The female reproductive system. Pregnancy and birth -- The endocrine system -- The nervous system and behavioral disorders -- The senses -- The skeleton -- The muscular system -- The skin.
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    Introduction to medical terminology -- The human body in health and disease -- The skeletal system -- The muscular system -- The cardiovascular system -- The lymphatic and immune systems -- The respiratory system -- The digestive system -- The urinary system -- The nervous system -- Special senses: the eyes and ears -- Skin : the integumentary system -- The endocrine system -- The reproductive systems -- Diagnostic procedures and pharmacology -- Comprehensive medical terminology review -- Appendixes.
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    Building a medical vocabulary: getting started -- Basic term components -- Fields of medical practice -- The medical record -- Integumentary system -- Musculoskeletal system -- Cardiovascular system -- Blood and lymph systems -- Respiratory system -- Nervous system -- Endocrine system -- Eye -- Ear -- Gastrointestinal system -- Urinary system -- Male reproductive system -- Female reproductive system.
  • "This is a complete and self-contained course in modern medical terminology. It is suitable for all students of the health occupations who will have a need to communicate with physicians, dentists, and other medical professionals. Little prior knowledge of anatomy, physiology, and pharmacology is required."
  • Bladder Cancer / Mark A. Rochester and John D. Kelly -- Renal Cell Cancer / Bryan Y. Wong and Wolfram E. Samlowski -- Prostate Cancer / Ajay Pahuja, Ali Thwaini, Thiaga Nambirajan and Patrick F. Keane -- Testicular Cancer / Daniel Rottke and Peter Albers -- Penile Cancer / Giorgio Pizzocaro -- LUTS/Benign Prostatic Hyperplasia / Katie Moore and Jay Khastgir -- Overactive Bladder and Incontinence / Vinay Kalsi, Abdul Chowdhury and Kim Mammen -- Urinary Tract Infections / Magnus J. Grabe -- Bladder Pain Syndrome/Interstitial Cystitis / Paul Irwin -- Chronic Prostatitis/Chronic Pelvic Pain Syndrome / José M. Reyes and Michael A. Pontari -- Urinary Tract Stones / William G. Robertson -- Erectile Dysfunction / Chi-Ying Li and David Ralph -- Male Hypogonadism / Aikaterini Theodoraki and Pierre-Marc Gilles Bouloux -- Renal Transplantation / Behdad Afzali, Kerem B. Atalar, Refik Gökmen and David J. A. Goldsmith -- Analgesia for Urological Procedures / Aza A. Mohammed, Rose McRobert and Brian Little -- Alternative or Complementary Treatments in Urology / Charlotte L. Foley, Sergiy Tadtayev and Tamsin J. Greenwell.
  • Medical Therapy of Ulcerative Colitis will serve as an invaluable resource for individual physicians use who treat patients with ulcerative colitis. The text presents a comprehensive overview of medical therapy for management of specific clinical scenarios and also a focus on the individual medications used to treat patients with ulcerative colitis. The book will be evidence based and focus on simplifying the current treatment to make it easy to understand. The chapters are written by experts in their fields and provide the most up to date information. This book will target gastroenterologists who focus on IBD, general gastroenterologists, fellows, and surgeons such as colorectal surgeons or GI surgeons who may treat patients with ulcerative colitis.
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    "Kirsten Ostherr's ambitious study explores 120 years of medical image-making to explain how visual representations shape medical education and practice. Marshaling powerful, vivid examples she demonstrates how medical images created by the healthcare industry, documentary filmmakers, experimental artists, and the mass media acquire cultural meaning and influence doctors' and patients' understandings of health and disease. Her analysis proceeds chronologically, turning from the earliest experiments with medical filmmaking by the American College of Surgeons, to the place of health films in the "golden age" of instructional film in the 1960s. Ostherr considers the shift to television as the dominant medium of health education, highlighting the evolving status of realism, the techniques employed to bridge the entertainment-education divide, the role of expert consultants and sponsors, and the tradeoffs made by professionals to reach a broad audience. The rise of physician advice segments on newsmagazines forms a transition between medical dramas like Marcus Welby, MD and more recent reality shows like Boston Med and Doctor 90210. Concluding with a section on advertising and social media in the health care setting, the book ends with ten key lessons for the future of medical media." -- [Publisher-supplied data]
  • Medical wisdom in the twenty-first century -- Caring for the patient -- Clinical dialogue and communication -- The art of clinical diagnosis -- Disease management and prevention -- Caring for dying patients and their families -- Masking a living as a clinician -- Staying up to date -- Mentoring tomorrow's physicians -- About your family and community -- Caring for you, the physician -- Ethics, credibility, and trust -- Planning for tomorrow -- Wise physicians, twenty-first century challenges, and doctoring.
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  • Getting Started in Medical Writing -- Basic Writing Skills -- From Page One to the End -- Technical Issues in Medical Writing -- What's Special About Medical Writing? -- How to Write a Review Article -- Case Reports, Editorials, Letters to the Editor, Book Reviews, and Other Publication Models -- Writing Book Chapters and Books -- How to Write a Research Protocol -- How to Write a Grant Proposal -- How to Write a Report of a Clinical Study -- Getting Your Writing Published.
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    Appendixes: Cardiopulmonary resuscitation (CPR) and basic life support -- Nursing diagnoses -- Laboratory values -- Answer key to review questions. Nervous system -- Acute intracranial problems -- Stroke -- Chronic neurologic problems -- Alzheimer's disease and dementia -- Peripheral nerve and spinal cord problems -- Musculoskeletal system -- Musculoskeletal trauma and orthopedic surgery -- Musculoskeletal problems -- Arthritis and connective tissue diseases -- Critical care -- Shock, systemic inflammatory response syndrome, and multiple organ dysfunction syndrome -- Respiratory failure and acute respiratory distress syndrome -- Emergency and disaster nursing. Nursing practice today -- Health disparities -- Culturally competent care -- Health history and physical examination -- Patient and family teaching -- Older adults -- Community-based nursing and home care -- Complementary and alternative therapies -- Stress and stress management -- Pain -- End-of-life and palliative care -- Addictive behaviors -- Inflammation and wound healing -- Genetics, altered immune responses, and transplantation -- Infection and human immunodeficiency virus infection -- Cancer -- Fluid, electrolyte, and acid-base imbalances -- Preoperative care -- Intraoperative care -- Postoperative care -- Visual and auditory systems -- Visual and auditory problems -- Integumentary system -- Integumentary problems -- Burns -- Respiratory system -- Upper respiratory problems -- Lower respiratory problems -- Obstructive pulmonary diseases -- Hematologic system -- Hematologic problems -- Cardiovascular system -- Hypertension -- Coronary artery disease and acute coronary syndrome -- Heart failure -- Dysrhythmias -- Inflammatory and structural heart disorders -- Vascular disorders -- Gastrointestinal system -- Nutritional problems -- Obesity -- Upper gastrointestinal problems -- Lower gastrointestinal problems -- Liver, pancreas, and biliary tract problems -- Urinary system -- Renal and uorologic problems -- Acute renal failure and chronic kidney disease -- Endocrine system -- Diabetes Mellitus -- Endocrine problems -- Reproductive system -- Breast disorders -- Sexually transmitted diseases -- Female reproductive problems -- Male reproductive problems --
  • Medicare chartbook. 3rd ed. 2005
    Kais Fam Found
    "Features more than 80 charts and tables with detailed information about the program and the seniors and younger people with disabilities who rely on Medicare for health insurance coverage."
  • Medicare spends a considerable amount of money on beneficiaries in their last year of life. This is often thought to be an issue of cost versus the intensity of care that end-of-life patients should receive. This way of framing the debate, however, overstates the importance of end-of-life spending, which is quantitatively modest compared to an ever-increasing Medicare budget. More salient is whether patients are receiving end-of-life care that matches their values and beliefs. Unfortunately, the evidence suggests that Medicare's tendency toward providing end-of-life care in a hospital inpatient setting is at odds with the preferences of patients.
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    Racial preoccupations and early cardiology -- Making normal populations and making difference in the Framingham and Jackson heart studies -- The durability of African American hypertension as a disease category -- The slavery hypothesis beyond genetic determinism -- Thiazide diuretics at a nexus of associations : racialized, proven, old, cheap -- BiDil: medicating the intersection of race and heart failure.
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    1. El vuelo de alta cota. Bibliografia (p. [187]-190).
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  • 1. Monoterpenes and related compounds from the medicinal plants of Africa / Michel Kenne Tchimene [and three others] -- 2. Sesquiterpenes from the medicinal plants of Africa / Maurice D. Awouafack [and three others] -- 3. Diterpenoids from the medicinal plants of Africa / Louis Pergaud Sandjo and Victor Kuete -- 4. Triterpenes and steroids from the medicinal plants of Africa / Louis Pergaud Sandjo and Victor Kuete -- 5. Essential oils from the medicinal plants of Africa / Oladipupo A. Lawal and Isiaka A. Ogunwande -- 6. Simple phenols, phenolic acids, and related esters from the medicinal plants of Africa / Guy B. Kougan [and three others] -- 7. Phenylpropanoids and related compounds from the medicinal plants of Africa / Victor Kuete -- 8. Coumarins and related compounds from the medicinal plants of Africa / Herve Martial Poumale Poumale [and four others] -- 9. Flavonoids and related compounds from the medicinal plants of Africa / Bathelemy Ngameni [and nine others] -- 10. Quinones and benzophenones from the medicinal plants of Africa / Kenneth O. Eyong, Victor Kuete and Thomas Efferth -- 11. Xanthones and anthranoids from the medicinal plants of Africa / Ofentse Mazimba [and three others] -- 12. Lignans and stilbenes from African medicinal plants / Apollinaire Tsopmo, Francis M. Awah and Victor Kuete -- 13. Tannins and related compounds from medicinal plants of Africa / Abdelaaty A. Shahat and Mohamed S. Marzouk -- 14. Alkaloids from the medicinal plants of Africa / Jean Duplex Wansi [and three others] -- 15. Ceramides, cerebrosides, and related long chains containing derivatives from the medicinal plants of Africa / Louis Pergaud Sandjo and Victor Kuete -- 16. Antibacterial, antifungal, and antiviral activities of African medicinal plants / Ashwell R. Ndhlala [and five others] -- 17. Antimalarial and other antiprotozoal products from African medicinal plants / Denis Zofou, Victor Kuete and Vincent P.K. Titanji -- 18. Antiproliferative potential of African medicinal plants / Victor Kuete, Katrin Viertel and Thomas Efferth -- 19. Anti-inflammatory and analgesic activities of African medicinal plants / Christian Agyare [and three others] -- 20. Antidiabetes activity of African medicinal plants / Roland N. Ndip, Nicoline F. Tanih and Victor Kuete -- 21. Antioxidant activity of African medicinal plants / Mikhail Olugbemiro Nafiu, Musa Oyewole Salawu and Mutiu Idowu Kazeem -- 22. African medicinal plants acting on the reproductive, cardiovascular, and central nervous systems / Emmanuel Mouafo Tekwu, Veronique Penlap Beng and Victor Kuete -- 23. Legislation on medicinal plants in Africa / Mainen Julius Moshi and Paulo Peter Mhame -- 24. Medicinal plants market and industry in Africa / Jean P. Dzoyem, Emmanuel Tshikalange and Victor Kuete.
  • A unified and single-source reference book providing significant data on a wide spectrum of medicinal herbs practiced worldwide and their chemical ingredients. 350 plants are dealt with in detail dovetailing their distinguishing botanical characters, chemical components and biomarkers of all the useful parts, authentic medicinal properties and the pharmacological actions they elicit. Constituent compounds have been grouped according to their natural product classification. This book is intended to oncompass an in-depth coverage of the chemistry of "Plant Products" such as alkaloids, terponoids, phenolics, etc. Emerging trends like aromatherapy and antioxidant therapy are discussed and a user's guide is appended at the end.--excerpted from book jacket.
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  • Medicinal plants classified in the family Annonaceae -- Medicinal plants classified in the family Myristicaceae -- Medicinal plants classified in the family Lauraceae -- Medicinal plants classified in the family Piperaceae -- Medicinal plants classified in the family Aristolochiaceae -- Medicinal plants classified in the family Nympheaceae -- Medicinal plants classified in the family Menispermaceae -- Medicinal plants classified in the family Polygonaceae -- Medicinal plants classified in the family Myrsinaceae -- Medicinal plants classified in the family Ebenaceae -- Medicinal plants classified in the family Bombacaceae -- Medicinal plants classified in the family Elaeocarpaceae -- Medicinal plants classified in the family Capparaceae -- Medicinal plants classified in the family Flacourtiaceae -- Medicinal plants classified in the family Passifloraceae -- Medicinal plants classified in the family Cucurbitaceae -- Medicinal plants classified in the family Connaraceae -- Medicinal plants classified in the family Anisophylleaceae -- Medicinal plants classified in the family Rosaceae -- Medicinal plants classified in the family Thymeleaceae -- Medicinal plants classified in the family Melastomataceae -- Medicinal plants classified in the family Rhizophoraceae -- Medicinal plants classified in the family Olacaceae -- Medicinal plants classified in the family Icacinaceae -- Medicinal plants classified in the family Euphorbiaceae -- Medicinal plants classified in the family Sapindaceae -- Medicinal plants classified in the family Anacardiaceae -- Medicinal plants classified in the family Simaroubaceae -- Medicinal plants classified in the family Meliaceae -- Medicinal plants classified in the family Rutaceae -- Medicinal plants classified in the family Loganiaceae -- Medicinal plants classified in the family Gentianaceae -- Medicinal plants classified in the family Apocynaceae -- Medicinal plants classified in the family Asclepiadaceae -- Medicinal plants classified in the family Solanaceae -- Medicinal plants classified in the family Verbenaceae.
  • Ch. 1. Superorder Austrobaileyanae (Croizat) Doweld ex M.W. Chase & Reveal, 2009 -- ch. 2. Superorder Magnolianae Takht., 1967 -- ch. 3. Superorder Lilianae Takht, 1967 -- ch. 4. Superorder Ranunculanae Takht. ex Reveal, 1992 -- ch. 5. Superorder Rosanae Takht., 1967 -- ch. 6. Superorder Saxifraganae Reveal, 1994 -- ch. 7. Superorder Santalanae Thorne ex Reveal, 1992 -- ch. 8. Superorder Caryophyllanae Takht., 1967 -- ch. 9. Superorder Asteranae Takht., 1967.
  • New strategies for traditional medicine -- Developing better herbal medicines in the post-genomic era -- Revitalization of the knowledge of herbs: a way forward to discovery of new drugs -- Ethnobotanical uses of the native flora from Brazilian north-eastern region -- Diversity and uses of the genus croton (euphorbiaceae) in Northeastern Brazil -- Ethnomedical knowledge among the "Quilombolas" from the Amazon region of Brazil with a special focus on plants used as nervous system tonics -- Advances in the knowledge of medicinal plants in Eastern Andalusia, Spain -- Tropical propolis: recent advances in chemical components and Botanical origin -- Anti-malarial plants used in folk medicine in Bangladesh -- Usnea sulcata motyka: an ethnomycological review of its use in traditional medicine -- Sirukurinjan: An ancient remedy for a modern incurable disease, diabetes -- Herbal drugs used for domestic animals -- Endophytes from medicinal plants as novel sources of bioactive compounds -- Advances in medicinal plants with antitumoral activity -- Medicinal plants: how are they used to treat neurological diseases? -- Inflammatory diseases: mechanisms and natural remedies -- Recent advances to evaluate anti-diabetic medicinal plants -- Botanical origin and Biological activity of propolis -- Bioactivity of plant essential oils -- Antibacterial and antiviral effects of aromatic plant-derived essential oils: a scientific and medicinal approach -- Strategies of solvent system selection for the isolation of natural products by countercurrent chromatography.
  • 1. Diseases of the cardiovascular system -- 2. Diseases of the respiratory system -- 3. Diseases of the ear, nose, and throat -- 4. Diseases of the gastrointestinal system -- 5. Diseases of the liver, biliary system and pancreas -- 6. Diseases of the endocrine system -- 7. Diabetes and other metabolic diseases -- 8. Diseases of the bones and joints -- 9. Diseases of the nervous system and voluntary muscle -- 10. Diseases of the eye -- 11. Diseases of the kidney and urinary system -- 12. Diseases of the haematological system -- 13. Diseases of the breast -- 14. Diseases of the skin -- 15. Infectious diseases.
  • Healthcare and Business -- Leadership and Governance -- Revenue Cycle -- Financial Definitions and Variances -- Income Statement -- Balance Sheet -- Statement of Cash Flows -- Financial Ratios -- Budgeting and Variance Analysis -- Strategic Planning and Business Planning -- Healthcare Insurance -- Managed Care -- Payment Methods -- Corporation and Hospital Structures -- Physician Employment and Compensation -- Medical Business Law and Regulations -- New Government Initiatives.
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    The religious and the medical -- The rise of modern medicine -- Cancer and medicine in historical perspective -- Development of palliative care services -- Development of pain control -- Medicine and euthanasia -- Observations and conclusions.
  • Environments, adaptation, and evolutionary medicine : should we be eating a stone age diet? / Sarah Elton -- Human protein requirements and infection stress among young children at the origins of agriculture / Stanley J. Ulijaszek -- Evolutionary perspectives on type 2 diabetes in Asia / Tessa M. Pollard, Alejandra Nunez-de la Mora, and Nigel Unwin -- Seasonality, climatic unpredictability, food deprivation, and polycystic ovary syndrome / Laurence Shaw and Sarah Elton -- Evolution and endocrinology : the regulation of pregnancy outcomes / Virginia J. Vitzthum -- Evolutionary paediatrics : a case study in applying Darwinian medicine / Helen Ball -- The role of helminthes in human evolution : implications for global health in the 21st century / A. Magdalena Hurtado ... [et al.] -- Nonbizarre delusions as strategic deception / Edward H. Hagen -- Practical aspects of evolutionary medicine / Gillian R. Bentley and Robert Aunger -- Comparative and evolutionary biology in medical and dental education / M.Christopher Dean -- Is there a place for evolutionary medicine in UK medical education? / Sarah Elton and Paul O'Higgins -- Would Darwin recognise himself here? / Jonathan Marks.
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    Empire's historical health component -- Illness-generating conditions of capitalism and empire -- The international market for health products and services -- Paths of resistance to empire in public health and health services -- Neoliberalism and health (with Rebeca Jasso-Aguilar) -- International trade agreements, medicine, and public health -- Macroeconomics and health -- The exportation of managed care -- Corporations, international financial institutions, and health services -- The "common sense" of health reform -- Stakeholders' constructions of global trade, public health, and health services -- Militarism, empire, and health -- Health and praxis : social medicine in Latin America -- Resistance and building an alternative future (with Rebeca Jasso-Aguilar).
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    Current questions over whether Hellenistic Egypt should be understood in terms of colonialism and imperialism, multicultural separatism, or integration and syncretism have never been closely studied in the context of healing. Yet illness affects and is affected by nutrition, disease and reproduction within larger questions of demography, agriculture and environment. It is crucial to every socio-economic group, all ages, and both sexes; perceptions and responses to illness are ubiquitous in all kinds of evidence, both Greek and Egyptian and from archaeology to literature. Examing all forms of healing within the specific socioeconomic and environmental constraints of the Ptolemies' Egypt, this book explores how linguistic, cultural and ethnic affiliations and interactions were expressed in the medical domain.
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    Introduction: Colonial embodiments -- Healing the body, healing the umma: Sufi saints and God's law in a corporeal city of virtue -- Medicine and the mission civilisatrice: a civilizing science and the French sociology of Islam in Algeria and Morocco, 1830-1912 -- The Many deaths of Dr. Émile Mauchamp: contested sovereignties and body politics at the court of the sultans, 1877-1912 -- Frédéric Le Play in Morocco? the paradoxes of French hygiene and colonial association in the Moroccan city, 1912-1937 -- Harem medicine and the sleeping child: law, traditional pharmacology, and the gender of medical authority -- A Midwife to modernity: the biopolitics of colonial welfare and birthing a scientific Moroccan nation, 1936-1956 -- Epilogue. Epistemologies embodied: Islam, France, and the postcolonial.
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    Yale confers first medical degree in colonial America, p. 3-5 -- The State of American medicine in 1810, p. 6-9 -- 1701-1810: The "Prehistory" of Yale in Medicine, p. 10-21 -- 1810-1860: "Articles of Union" : the Medical Institution of Yale College, p. 22-47 -- "A Pledge to the world": medical schools and the making of American physician in the mid-nineteenth century / John Harley Warner, p. 48-51 -- 1860-1910: Yale's Medical Institution on the brink: steps toward the revolution in medicine, p. 52-77-- 1910-1960: The Metamorphosis: Yale School of Medicine, transformed, p. 78-125 -- Yale School of Medicine in the twentieth century: expanding the science, and the art, of medicine / Thomas P. Duffy, p. 126-9 -- 1960-2010: From the birth of Medicare to the promise of personalized medicine, p. 131-89 -- Looking back from the future / Harlan M. Krumholz, p. 189 -- Training tomorrow's physicians at Yale / Richard Belitsky, p. 190 -- The Future of clinical research at Yale School of Medicine / Mary E. Tinetti, p. 191 -- Genes, genomes, and the future of medicine / Richard P. Lifton, p. 192 -- Digital thinking and the power of one / James E. Rothman, p. 193.
  • Since 1986, Medicine for the Outdoors has been hailed as the definitive take-along manual on the subject. Packed with step-by-step instructions and how-to explanations, this updated edition tells you the best way to respond to just about any medical problem. Logically organized, simple-to-understand enhanced illustrations and an increased focus on new topics mean this medical reference book may literally save your life. Whether you're venturing into mountains, deserts, forests, or out to sea, it belongs in your pack!
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  • This book outlines risk assessments for 28 diseases and medical conditions including the following aspects: genetics, biochemistry, serology, past medical history, family history, co-morbidities, age, gender, ethnicity, nutrition and lifestyle. Recommendations are made for how to avoid, eliminate or mitigate risks. Preventing measures concerning chemical compound intake, lifestyle and nutrition are proposed. The unique content and approach of the book to chronic disease management make it a state-of-the-art reference work, addressing a missing component of medical care and reflecting the cutting edge of preventive medicine.
  • Based on the principle of 'medicine of the person', an attitude that embeds personal relationships and ethics in medical practice, this text considers the ideas of Paul Tournier, an influential figure whose thinking has had a substantial impact on the spiritual and psychosocial aspects of routine patient care.
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    Infectious disease -- Hospital based medicine -- Rheumatology -- Pulmonary disease -- Cardiology -- Endocrinology and metabolic disease -- Gastroenterology -- Nephrology -- Hematology and oncology -- Neurology -- Dermatology -- General medicine and prevention -- Allergy and immunology -- Geriatrics -- Women's health.
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    Allergy and immunology -- Cardiology -- Endocrinology -- Gastroenterology -- Hematology -- Infectious diseases -- Nephrology -- Oncology -- Pulmonology -- Rheumatology -- Neurology -- Pharmacology.
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    Allergy and immunology -- Cardiology -- Endocrinology -- Gastroenterology -- Hematology -- Infectious diseases -- Nephrology -- Oncology -- Pulmonology -- Rheumatology -- Neurology -- Pharmacology.
  • Physician-scientists are unusual creatures. While we are drawn to the clinical challenges of our patients, we are also drawn to the opportunities that our patients' medical problems bring to science. This book contains the unique experiences and encounters that drew 21 accomplished physician-scientists to this profession. These personal stories are those of people and circumstances that have had profound effects on our career decisions, our creative opportunities, and our lives. These stories also serve to highlight the lessons learned along the way and the distinct attributes of these women and men of medicine and science. Our combined hope is that our collective biographies will enhance the public understanding of our profession, will move people from medicine to science and from science to medicine, and will inspire those who are contemplating this extraordinary profession.
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    Medicine's Michelangelo is a remarkable and first major biography of Frank H. Netter, MD, written by his daughter, Francine Mary Netter. She captures the character of the man and tells his life story using not only her remembrances but also Frank Netter's own autobiographical notes, personal correspondence and private files, publications of his work and public archives, and more than 100 interviews with family members, artists, distinguished practitioners and scientists. More than account of his momentous career, this book provides a personal introduction to the man behind the art.--Publisher description
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    Emotion theory and medical history / Fay Bound Alberti -- Emotions in the early modern medical tradition / Fay Bound Alberti -- Patients and passions / Thomas Dixon -- Languages and landscapes of emotion / -Hilary Marland -- "Cold calculations in the faces of horrors?" / Bertrand Taithe -- Sympathy under the knife / Paul White -- Fear and loathing in the laboratory and clinic / Otniel Dror -- From Clever Hans to Michael Balint / Rhodri Hayward -- Diagnosing with feeling / Susan Lanzoni.
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    1. Sport as medicine: ideas of health, sport and exercise -- 2. This sporting life: injuries and medical provision -- 3. Sports medicine: pioneers and specialization -- 4. Science and the making of the athletic body -- 5. Testing times: drugs, anti-doping and ethics -- 6. Repairing the athletic body: treatments, practices and ethics -- 7. Medicine, sport and the female body -- 8. Boxing: a medical history.
  • "Complete, yet concise, Medicine: A Competency-Based Companion provides the core information you need to think like an experienced clinician during your medical rotation. This handy, pocket-sized medical reference book hones in on the must-know differential diagnoses of the common medical presentations and guides you through the most up-to-date and effective approaches to treatment, equipping you to excel."--Publisher's website.
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    Shortness of breath -- Chest pain -- Abdominal pain -- Hormonal and electrolyte imbalance -- Preventive medicine -- Head symptoms -- Blood issues -- Swelling, musculoskeletal, and skin issues.
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    Chest pain -- Shock -- Coronary heart disease -- Myocardial infarction -- Heart failure -- Bradyarrhythmias -- Tachyarrhythmias -- Hypertension -- Valvular heart disease -- Vascular disease -- Syncope -- Dyspnea -- Cough -- Chronic obstructive pulmonary disease -- Asthma -- Pulmonary embolism -- Interstitial lung disease -- Pleural effusions -- Lung cancer -- Acid-base disturbances -- Fluid and electrolytes -- Acute renal failure -- Chronic kidney disease -- Glomerular disease -- Nephrolithiasis -- Hematuria -- Fever and rash -- Pneumonia -- Sexually transmitted diseases -- Urinary tract infections -- Tuberculosis -- Gastroenteritis -- Infective endocarditis -- Meningitis -- HIV part I: primary care of the HIV-infected patient -- HIV part II: prophylaxis and treatment of opportunistic infections in HIV -- Abdominal pain -- Diarrhea -- Peptic ulcer disease and gastritis -- Inflammatory bowel disease -- Hepatitis -- Cirrhosis -- Cholestatic liver disease -- Pancreatitis -- Colorectal cancer -- Weight loss -- Hyperthyroidism -- Hypothyroidism -- Diabetes mellitus -- Hypercalcemia -- Diseases of the adrenal gland -- Pituitary disease -- Nutritional disorders -- Dyslipidemia -- Acute monoarticular arthritis -- Low back pain -- Rheumatoid arthritis -- Seronegative spondyloarthropathies -- Connective tissue diseases -- Vasculitis -- Amyloidosis -- Anemia -- Hemolytic anemia -- Adenopathy -- Bleeding disorders -- Breast cancer -- Prostate cancer -- Leukemia/lymphoma -- Complications of cancer therapy -- Paraneoplastic disorders.
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  • Medicines for women 2015
    Springer
    In this definitive new text, the major medicines, devices and vaccines used by women worldwide are brought together for the first time in a single volume. Written and edited by international experts with an evidence-based approach, Medicines for Women offers a comprehensive summary of all key areas. In the first part, issues relating to female drug exposure and prescribing to subgroups of women ℓ́ℓ for example during pregnancy and lactation, and to adolescent women ℓ́ℓ are presented in the context of contemporary clinical practice. In the second part, specific groups of medicines are reviewed, including oral contraceptives (with an additional chapter on venous thromboembolism), emergency contraception, contraceptive devices, treatment of chronic pelvic pain, hormone replacement therapy, bisphosphonates, herbal medicines for women, and human papilloma virus vaccines. Every chapter reviews and summarizes the efficacy and safety of each group of products and concludes with a useful set of clinical ℓ́ℓtake-homeℓ́ℓ messages. In the third part of the book, broader perspectives are presented ℓ́ℓ from a primary-care overview of prescribing for women, through to regulatory, political and religious aspects, including issues in developing countries. The two final chapters focus on communicating the benefits and risks of medicines for women. This book is aimed at prescribers, other healthcare professionals and students of womenℓ́ℓs health throughout the world. It is an extremely valuable resource for all in clinical practice, for students of medicine, nursing, pharmacy and related sciences, and also for those in medicines regulation, pharmacovigilance and the pharmaceutical industry.
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    1. A-Ćul. Yud 83- (Yu 66-2212) -- 2. D-Giu YuD 83- (Yu...).
  • The orthopaedic surgeon's viewpoint -- The legal viewpoint -- The orthopaedic surgeon in court -- The shoulder -- The humerus -- The elbow -- The forearm -- The wrist -- Hand injuries -- The hip -- The femur -- The knee -- The tibia and fibula -- The ankle -- The foot -- The pelvis and acetabulum -- The cervical spine: Whiplash injury -- The cervical spine: Fractures -- Assessment of patients with low back problems in the medicolegal setting -- Thoracic and lumbar spine fractures -- Traumatic spinal cord injuries -- Head injury -- Soft tissue injuries, including burns -- Peripheral nerve injuries -- The psychological effects of trauma -- Complex regional pain syndrome -- Arm pain and work -- Radiology in medicolegal practice -- Hand-arm vibration syndrome -- Medicolegal aspects of cauda equina syndrome.
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    "This unique examination of medieval medicine as detailed in physician's manuals of the period reveals a more sophisticated approach to the medical arts than expected for the time. Far from the primitive and barbaric practices the Middle Ages may conjure up in our minds, doctors during that time combined knowledge, tradition, innovation, and intuition to create a humane, holistic approach to understanding and treating every known disease. In fact, a singularly authoritative medical source of the period, Lily of Medicine, continued to provide crucial study for students and practitioners of medicine almost four centuries after its completion in 1305. This unprecedented book investigates the extensive capabilities of physicians who relied on practice, observation, and imagination before the supremacy of mechanistic views and technological aids. Medieval Medicine: The Art of Healing, from Head to Toe is a comprehensive look at diseases as they were described, classified, explained, assessed, and treated by doctors of the age. The author methodically compares a dozen encyclopedic manuals in which both the fundamental understanding of healthy functions and the specific response to diseases were summarized, viewing the information through a medieval perspective rather than based upon modern criteria." -- Publisher's description.
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    A compilation of medicines and herbals taken from medieval texts, 1170 and 1325.
  • Part 1. The Basics of a Mediterranean Diet -- Introduction -- History, Composition, Adherence Scores -- Part 2. Effects on Diseases -- Mechanisms of Action and Effects on Diseases -- Cardiovascular Diseases -- Alzheimer's Disease -- Cancer -- Arthritis, Allergies, and Immunologic Disorders -- Diabetes and Metabolic Syndrome -- Part 3. Weight Loss and Obesity -- Weight, Obesity -- Part 4. Macronutrients -- Macronutrients in an Adherence Score: Carbohydrates, Proteins, Fats, and Alcohol -- Fats and Oils -- Carbohydrates -- Proteins -- Alcohol -- Part 5. Adopting a Mediterranean Diet -- Goal Is Success in Adoption -- Meal Plans -- Shopping List, Keep On Hand -- Resources -- Recipes.
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  • The adam Health Illustrated Encyclopedia includes over 4,000 articles about diseases, tests, symptoms, injuries, and surgeries. It also contains an extensive library of medical photographs and illustrations.
  • Global micronutrient deficiencies in childhood and impact on growth and survival : challenges and opportunities / Imdad, A.; Bhutta, Z.A. -- Micronutrients in the treatment of stunting and moderate malnutrition / Penny, M.E. -- Zinc requirements : assessment and population needs / Hambidge, K.M.; Miller, L.V.; Krebs, N.F. -- Role of zinc in child health and survival / Black, R.E.; Fischer Walker, C. -- Global burden and significance of multiple micronutrient deficiencies in pregnancy / Darnton-Hill, I. -- Intervention strategies to address multiple micronutrient deficiencies in pregnancy and early childhood / Imdad, A.; Bhutta, Z.A. -- Vitamin A supplementation, infectious disease and child mortality : a summary of the evidence / Thorne-Lyman, A.; Fawzi, W.W. -- Issues and controversies with vitamin A in childhood / Murgu¡a Peniche, M.T. -- Influence of inflammatory disorders and infection on iron absorption and efficacy of iron-fortified foods / Hurrell, R.F. -- Safety of iron fortification and supplementation in malaria-endemic areas / Brittenham, G.M. -- Are weaning infants at risk of iodine deficiency even in countries with established iodized salt Programs? / Zimmermann, M.B. -- Current challenges in meeting global iodine requirements / Eastman, C.J.; Jooste, P. -- Folate and vitamin B12 : function and importance in cognitive development / Troen, A.M. -- Pros and cons of increasing folic acid and vitamin B12 intake by fortification / Allen, L.H. -- Concluding remarks.
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  • Meeting the Needs of Older Adults with Serious Illness: Challenges and Opportunities in the Age of Health Care Reform provides an introduction to the principles of palliative care, describes current models of delivering palliative care across care settings, and examines opportunities in the setting of healthcare policy reform for palliative care to improve outcomes for patients, families and healthcare institutions. The United States is currently facing a crisis in health care marked by unsustainable spending and quality that is poor relative to international benchmarks. Yet this is also a critical time of opportunity. Because of its focus on quality of care, the Affordable Care Act is poised to expand access to palliative care services for the sickest, most vulnerable, and therefore most costly, 5% of patients- a small group who nonetheless drive about 50% of all healthcare spending. Palliative care is specialized medical care for people with serious illnesses. It focuses on providing patients with relief from the symptoms, pain, and stress of a serious illness, whatever the diagnosis or stage of illness. The goal is to improve quality of life for both the patient and the family. Research has demonstrated palliative care?s positive impact on health care value. Patients (and family caregivers) receiving palliative care experience improved quality of life, better symptom management, lower rates of depression and anxiety, and improved survival. Because patient and family needs are met, crises are prevented, thereby directly reducing need for emergency department and hospital use and their associated costs. An epiphenomenon of better quality of care, the lower costs associated with palliative care have been observed in multiple studies. Meeting the Needs of Older Adults with Serious Illness: Challenges and Opportunities in the Age of Health Care Reform, a roadmap for effective policy and program design, brings together expert clinicians, researchers and policy leaders, who tackle key areas where real-world policy options to improve access to quality palliative care could have a substantial role in improving value.
  • Meiosis 2009.
    Karger
    The meiotic recombination hotspots of Schizosaccharomyces pombe / Pryce, D.W.; McFarlane, R.J. -- Meiotic recombination and crossovers in plants / De Muyt, A. ... [et al.] -- Meiosis in cereal crops : the grasses are back / Martinez-Perez, E. -- Homologue pairing, recombination and segregation in Caenorhabditis elegans / Zetka, M. -- Homolog pairing and segregation in Drosophila meiosis / McKee, B.D. -- The mammalian synaptonemal complex : a scaffold and beyond / Yang, F.; Wang, P.J. -- The dance floor of meiosis : evolutionary conservation of nuclear envelope attachment and dynamics of meiotic telomeres / Alsheimer, M. -- Cohesin complexes and sister chromatid cohesion in mammalian meiosis / Suja, J.A.; Barbero, J.L. -- Variation in patterns of human meiotic recombination / Khil, P.P.; Camerini-Otero, R.D. -- Maternal origin of the human aneuploidies are homolog synapsis and recombination to blame? Notes (learned) from the underbelly / Garcia-Cruz, R.; Roig, I.; Garcia Caldés, M. -- Inverted meiosis : the true bugs as a model to study / Viera, A.; Page, J.; Rufas, J.S. The meiotic recombination hotspots of Schizosaccharomyces pombe / D.W. Pryce, R.J. McFarlane -- Meiotic recombination and crossovers in plants / A. De Muyt ... [et al.] -- Meiosis in cereal crops : the grasses are back / E. Martinez-Perez -- Homologue pairing, recombination, and segregation in Caenorhabditis elegans / M. Zetka -- Homolog pairing and segregation in Drosophila meiosis / B.D. McKee -- The mammalian synaptonemal complex : a scaffold and beyond / F. Yang, P.J. Wang -- The dance floor of meiosis : evolutionary conservation of nuclear envelope attachment and dynamics of meiotic telomeres / M. Alsheimer -- Cohesin complexes and sister chromatid cohesion in mammalian meiosis / J.A. Suja, J.L. Barbero -- Variation in patterns of human meiotic recombination / P.P. Khil, R.D. Camerini-Otero -- Maternal origin of the human aneuploidies are homolog : synapsis and recombination to blame? notes (learned) from the underbelly / R. Garcia-Cruz, I. Roig, M. Garcia Caldes -- Inverted meiosis : the true bugs as a model to study / A. Viera, J. Page, J.S. Rufas.
  • Structure-activity relationships (SAR) of melanocortin and agouti-related (AGRP) peptides / Anamika Singh, Erica M. Haslach and Carrie Haskell-Luevano -- Melanocortin signalling mechanisms / Paula C. Eves and John W. Haycock -- Distribution and function of melanocortin receptors within the brain / Kathleen G. Mountjoy -- Drugs, exercise, and the melanocortin-4 receptor: different means, same ends: treating obesity / Jay W. Schaub, Erin B. Bruce, and Carrie Haskell-Luevano -- Melanocortins in brain inflammation: the role of melanocortin receptor subtypes / Ruta Muceniece and Maija Dambrova -- Melanocortins and the cholinergic anti-inflammatory pathway / Daniela Giuliani ... [et al.] -- Melanocortin control of cell trafficking in vascular inflammation / Hetal B. Patel ... [et al.] -- Terminal signal: anti-inflammatory effects of α-melanocyte-stimulating hormone related peptides beyond the pharmacophore / Thomas Brzoska ... [et al.] -- Protective effects of melanocortins in systemic host reactions / Stefano Gatti ... [et al.] -- Development of α-melanocortin analogs for melanoma prevention and targeting / Zalfa A. Abdel-Malek -- MSH radiopeptides for targeting melanoma metastases / Alex N. Eberle ... [et al.] -- Applications of the role of α-MSH in ocular immune privilege / Andrew W. Taylor and Darren Lee.
  • Melanocytic Lesions: A Case Based Approachprovides a concise yet comprehensive guidelineon how to diagnose common as well as problematic and challenging melanocytic lesions.In the first 11 chapters, each entityis illustrated by an actual case; followed by discussion of how the diagnosis is reached, of the histologic differential diagnoses, and of diagnostic pitfalls; and ends with bulleted teaching points.Pertinent and up to date referencesare included at the end of each chapter. The latter chapterscover current microstaging and classification of melanoma, ancillary techniques including immunohistochemistry as well as available molecular assays and molecular targeted therapy. Melanocytic Lesions: A Case Based Approach serves as a useful resource for pathologists, dermatologists and researchers dealing with melanocytic lesions.
  • Print Material
  • The book provides comprehensive insights into molecular changes in malignant melanoma. The general mechanisms of melanoma growth and development are described, as well as new research findings. Our current knowledge on the molecules involved in cell transformation and tumor progression will soon lead to sophisticated, targeted therapies. Recent studies with targeted b-RAF inhibitors have given us grounds to hope that these therapies will be successful. Melanoma Development- Molecular Biology, Genetics and Clinical Application aims to contribute to this knowledge. Summarizing the newest data and presenting upcoming research areas in the field, the book will be of great interest to basic researchers and physicians working in the important fields of melanoma, cancer research, therapy and dermatology.
  • The book aims to cover basic physiologic functions of melatonin, and its therapeutic applications in humans for a variety of clinically relevant disorders. This bookcontains chapters on the recent aspects of melatonin physiology, its receptors and their role in mitochondrial function, its immunomodulatory role and importance in seasonal dependent diseases, role in human reproduction, role in sleep, circadian rhythm and sleep disorders, role in neurologic disorders such as Parkinsons disease, Alzheimers disease. Additionally, melatonins therapeutic use in neurobehavioral disorders in children, migraine and tension headache is also covered in this book. Melatonins antioxidant role in Duchennes muscular dystrophy and in glaucoma have also been discussed in short chapters. Two major melatonin agonists, ramelteon and agomelatine are discussed extensively on their current clinical application and ongoing research. Two chapters on agomelatonin and its role in mood disorders, particularly depressive disorders, are an important feature of this book. The chapters are written by experts from the global academia recognized for their original research and published work in the field of melatonin science.
  • "This new edition presents information on how melatonin is synthesized and produced in the body as well as how this hormone affects several diseases. The book heavily focuses on prevention as well as treatment of various human disease states including behavior disorders, mental disorders, breast cancer, bone health, and gastrointestinal diseases. It covers the role of melatonin in the prevention of oxidative stress, mutagenesis, sun damage, ocular health, gut motility, and detoxification. It also presents mechanisms of melatonin action in humans including cell modulation, signaling mechanisms, protective effects, and melatonin receptors as well as its role as an antioxidant"--Provided by publisher.
  • This inclusive text describes hot melt extrusion for pharmaceutical applications, focusing on the materials used for the preparation of solid dispersions, fundamentals for preparing such systems and novel applications using extrusion technology. Highlighting viewpoints from the academic, excipient, equipment, product development and regulatory communities, this comprehensive text compiles input from industry thought leaders to illustrate strategies and technologies for applying hot melt extrusion for drug product development while also providing insight into the path forward for the technology in years to come.
  • Print Material
  • Membrane fusion techniques. Part [A]-B pt. A-B, 1993.
    ScienceDirect
    pt. B ScienceDirect
  • From intramolecular asymmetries to raft assemblies: a short guide for the puzzled in lipidomics / Ephraim Yavin and Annette Brand -- Regulatory aspects of membrane microdomain (raft) dynamics in live cells: a biophysical approach / János Matkó and János Szöllosi -- Lipid raft membrane skeletons / Elizabeth J. Luna ... [et al.] -- Role of cholesterol in membrane microdomain signaling / Christopher J. Fielding -- Raft lipid metabolism in relation to alkyl-lysophospholipid-induced apoptosis / Arnold H. van der Luit, Marcel Verheij, and Wim J. van Blitterswijk -- Role of lipid rafts in signal transduction and synaptic plasticity of neural cells / Markus Delling and Melitta Schachner -- Role of rafts in virus fusion and budding / Wu Ou and Jonathan Silver -- Alterations in raft lipid metabolism in aging and neurodegenerative disorders / Mark P. Mattson, Roy G. Cutler, and Norman J. Haughey -- Caveolin and cancer: a complex relationship / Mordechai Liscovitch ... [et al.] -- Dietary modulation of lipid rafts: implications for disease prevention and treatment / Mark P. Mattson.
  • The book is structured in five sections, each containing several chapters written by experts and major contributors to particular topics. The volume starts with a historical perspective and fundamental principles of membrane potential imaging and continues to cover the measurement of membrane potential signals from dendrites and axons of individual neurons, measurements of the activity of many neurons with single cell resolution, monitoring of population signals from the nervous system, and concludes with the overview of new approaches to voltage-imaging. The book is targeted at all scientists interested in this mature but also rapidly expanding imaging approach.
  • Membrane Proteins - Production and Function Characterization a volume of Methods in Enzymology, encompasses chapters from the leading experts in the area of membrane protein biology. The chapters provide a brief overview of the topics covered and also outline step-by-step protocol. Illustrations and case example images are included wherever appropriate to help the readers understand the schematics and general experimental outlines.
  • Online tools for predicting integral membrane proteins / H. Bigelow and B. Rost -- In silico identification of novel G protein coupled receptors / M.N. Davies and D.R. Flower -- Transcriptome-based identification of candidate membrane proteins / E.J. Evans ... [et al.] -- Separation of thylakoid membrane proteins by sucrose gradient ultracentrifugation or blue native-SDS-PAGE two-dimensional electrophoresis / G.M. D'Amici, C.G. Huber and L. Zolla -- Extraction of yeast mitochondrial membrane proteins by solubilization and detergent/polymer aqueous two-phase partitioning / H. Everberg, N. Gustavsson and F. Tjerneld -- 16-BAC/SDS-PAGE analysis of membrane proteins of yeast mitochondria purified by free flow electrophoresis / R.J. Braun ... [et al.] -- Sequential detergent extraction prior to mass spectrometry analysis / F.M. McCarthy, A.M. Cooksey and S.C. Burgess -- Enrichment of brain plasma membranes by affinity two-phase partitioning / J. Schindler and H.G. Nothwang -- Protocol to enrich and analyze plasma membrane proteins / R.J. Wisniewski -- Proteomic analysis of the lymphocyte plasma membrane using cell surface biotinylation and solution-phase isoelectric focusing / M.J. Peirce, A.P. Cope and R. Wait -- Identification of target membrane proteins as detected by phage antibodies / C.A. Geuijen, A.Q. Bakker and J. de Kruif -- Membrane protease degradomics: proteomic identification and quantification of cell surface protease substrates / G.S. Butler ... [et al.] -- Purification of basolateral integral membrane proteins by cationic colloidal silica-based apical membrane subtraction / R.J. Goode and R.J. Simpson -- Moving closer to the lipid raft proteome using quantitative proteomics / L.J. Foster -- Use of sequential chemical extractions to purify nuclear membrane proteins for proteomics identification / N. Korfali ... [et al.] -- Isolation of extracellular membranous vesicles for proteomic analysis / R.A. Mathias ... [et al.] -- Enrichment of human platelet membranes for proteomic analysis / D.W. Greening ... [et al.] -- Detergents and chaotropes for protein solubilization before two-dimensional electrophoresis / T. Rabilloud -- Two-dimensional separation of membrane proteins by 16-BAC-SDS-PAGE / H.G. Nothwang and J. Schindler -- MudPIT analysis: application to human heart tissue / K.G. Kline and C.C. Wu -- Liquid chromatography MALDI MS/MS for membrane proteome analysis / N. Wang, J.B. Young and L. Li -- Cysteinyl-tagging of integral membrane proteins for proteomic analysis using liquid chromatography-tandem mass spectrometry / S.K. Mitra and M.B. Goshe -- Quantitative proteomics analysis of pancreatic zymogen granule membrane proteins / X. Chen and P.C. Andrews.
  • The role of ion channels in hypoxic pulmonary vasoconstriction / E. Kenneth Weir ... [et al.] -- Two-pore domain K channels and their role in chemoreception / Keith J. Buckler -- Intricate interaction between store-operated calcium entry and calcium-activated chloride channels in pulmonary artery smooth muscle cells / Abigail S. Forrest ... [et al.] -- The role of intracellular ion channels in regulating cytoplasmic calciumin pulmonary arterial mmooth [i.e. smooth] muscle : which store and where? / A. Mark Evans -- Ca2 oscillations regulate contraction of intrapulmonary smooth muscle cells / Michael J. Sanderson, Yan Bai, and Jose Perez-Zoghbi -- Introduction to TRP channels : structure, function, and regulation / Michael Y. Song and Jason S.-J. Yuan -- Physiological functions of transient receptor potential channels in pulmonary arterial smooth muscle cells / Xiao-Ru Yang, Mo-Jun Lin, and James S.K. Sham -- The contribution of TRPC1 and STIM1 to capacitative Ca2 entry in pulmonary artery / Lih Chyuan Ng, Judith A. Airey, and Joseph R. Hume -- Store-operated calcium entry channels in pulmonary endothelium : the emerging story of TRPCS and Orai1 / Donna L. Cioffi, Christina Barry, and Troy Stevens -- TRPM2 channel regulates endothelial barrier function / Claudie M. Hecquet, Gias U. Ahmmed, and Asrar B. Malik -- A proposed mitochondrial-metabolic mechanism for initiation and maintenance of pulmonary arterial hypertension in fawn-hooded rats : the Warburg model of pulmonary arterial hypertension / Jalees Rehman and Stephen L. Archer -- The role of classical transient receptor potential channels in the regulation of hypoxic pulmonary vasoconstriction / B. Fuchs ... [et al.] -- Developmental regulation of oxygen sensing and ion channels in the pulmonary vasculature / David N. Cornfield -- Hypoxic regulation of ion channels and transporters in pulmonary vascular smooth muscle / Larissa A. Shimoda -- CLC-3 chloride channels in the pulmonary vasculature / Joseph R. Hume ... [et al.] -- Role of bone morphogenetic protein receptors in the development of pulmonary arterial hypertension / Nicholas W. Morrell -- Cross talk between Smad, MAPK, and actin in the etiology of pulmonary arterial hypertension / James West -- Notch signaling in pulmonary hypertension / Patricia A. Thistlethwaite, Xiaodong Li, and Xiaoxue Zhang -- Rho kinase-mediated vasoconstriction in pulmonary hypertension / Ivan F. McMurtry ... [et al.] -- The serotonin hypothesis of pulmonary hypertension revisited / Margaret R. MacLean and Yvonne Dempsie -- Impaired vascular endothelial growth factor signaling in the pathogenesis of neonatal pulmonary vascular disease / Steven H. Abman -- Mitochondrial regulation of oxygen sensing / Navdeep S. Chandel -- Reactive oxygen species and RhoA signaling in vascular smooth muscle : role in chronic hypoxia-induced pulmonary hypertension / Thomas C. Resta, Brad R.S. Broughton, and Nikki L. Jernigan -- Polyamine regulatory pathways as pharmacologic targets in pulmonary arterial hypertension / Mark N. Gillespie and Jack W. Olson -- 5-HT receptors and Kv channel internalization / Angel Cogolludo and Francisco Perez-Vizcaino -- KCNQ potassium channels : new targets for pulmonary vasodilator drugs? / Alison M. Gurney, Shreena Joshi, and Boris Manoury -- Receptor tyrosine kinase inhibitors in rodent pulmonary hypertension / Liliana Moreno-Vinasco and Joe G.N. Garcia -- PDGF receptor and its antagonists : role in treatment of PAH / Friedrich Grimminger and Ralph Theo Schermuly -- PPAR[gamma] and the pathobiology of pulmonary arterial hypertension / Marlene Rabinovitch -- Targeting TASK-1 channels as a therapeutic approach / Andrea Olschewski -- Pharmacological targets for pulmonary vascular disease : vasodilation versus anti-remodelling / Matthew Thomas.
  • Membrane trafficking 2008
    Springer Protocols
    Pt. I. Yeast Cells -- Ch. 1. Freight management in the cell / Johannes M. Herrmann, Anne Spang -- Ch. 2. High-throughput protein extraction and immunoblotting analysis in saccharomyces cerevisiae / Todd C. Lorenz, Vikram C. Anand, Gregory S. Payne -- Ch. 3. Genome-wide analysis of membrane transport using yeast knockout arrays / Helen E. Burston, Michael Davey, Elizabeth Conibear -- Ch. 4. A cell-free system for reconstitution of transport between prevacuolar compartments and vacuoles in saccharomyces cerevisiae / Thomas A. Vida -- Ch. 5. In vitro analysis of the mitochondrial preprotein import machinery using recombinant precursor polypeptides / Dorothea Becker, Martin Krayl, Wolfgang Voos -- Ch. 6. In vitro import of proteins into isolated mitochondria / Karl Bihlmaier, Melanie Bien, Johannes M. Herrmann -- Ch. 7. Synthesis and sorting of mitochondrial translation products / Heike Bauerschmitt, Soledad Funes, Johannes M. Herrmann -- Ch. 8. In vivo labeling and analysis of mitochondrial translation products in budding and in fission yeasts / Karine Gouget, Fulvia Verde, Antoni Barrientos -- Ch. 9. Exploring protein-protein interactions involving newly synthesized mitochondrial DNA encoded proteins / Darryl Horn, Flavia Fontanesi, Antoni Barrientos -- Ch. 10. Purification of yeast membranes and organelles by sucrose density gradient centrifugation / Jennifer Chang, Victoria Ruiz, Ales Vancura -- Ch. 11. Microscopic analysis of lipid droplet metabolism and dynamics in yeast / Heimo Wolinski, Sepp D. Kohlwein -- Ch. 12. Use of bimolecular fluorescence complementation (BiFC) in yeast saccharomyces cerevisiae / Kari-Pekka Skarp, ... [et al.] -- Pt. II. Mammalian cells -- Ch. 13. Using quantitative fluorescence microscopy to probe organelle assembly and membrane trafficking / Brian Storrie, Tregei Starr, Kimberly Forsten-Williams -- Ch. 14. Measuring secretory membrane traffic / Vytaute Starkuviene, ... [et al.] -- Ch. 15. A correlative light and electron microscopy method based on laser micropatterning and etching / Julien Colombelli, ... [et al.] -- Ch. 16. Approaches to investigate the role of signaling in ER-to-Golgi transport / Laura J. Sharpe, Ximing Du, Andrew J. Brown -- Ch. 17. Recruitment of coat proteins to peptidoliposomes / Gregor Suri, Martin Spiess, Pascal Crottet -- Ch. 18. SNAREs mediated fusion of liposomes / Jérôme Vicogne, Jeffrey E. Pessin -- Ch. 19. Use of polarized PC12 cells to monitor protein localization in the early biosynthetic pathway / Ragna Sannerud, ... [et al.] -- Ch. 20. Tracking the transport of E-cadherin to and from the plasma membrane / Matthew P. Wagoner, Kun Ling, Richard A. Anderson -- Ch. 21. Analysis of nucleocytoplasmic shuttling of NFkB proteins in human leukocytes / Chandra C. Ghosh ... [et al.] -- Ch. 22. Imaging pHluorin-based probes at hippocampal synapses / Stephen J. Royle, ... [et al.] -- Ch. 23. Analysis of receptor tyrosine kinase internalization using flow cytometry / Ning Li, Kristen S. Hill, Lisa A. Elferink -- Ch. 24. Measurement of receptor endocytosis and recycling / Jane M. Knisely, Jiyeon Lee, Guojun Bu -- Ch. 25. Styryl dye-based synaptic vesicle recycling assay in cultured cerebellar granule neurons / Victor Anggono, Michael A. Cousin, Phillip J. Robinson -- Ch. 26. Use of quantitative immunofluorescence microscopy to study intracellular trafficking / Vincent Blot, Timothy E. McGraw -- Ch. 27. Dissecting GLUT4 traffic components in L6 myocytes by fluorescence-based, single cell assays / Costin N. Antonescu, Varinder K Randhawa, Amira Klip -- Ch. 28. Functional genetic analysis of the mammalian mitochondrial DNA encoded peptides / Maria Pilar Bayona-Bafaluy, ... [et al.].
  • Viral entry / S.B. Sieczarski and G.R. Whittaker -- The many mechanisms of viral membrane fusion proteins / L.J. Earp ... [et al.] -- The role of the cytoskeleton during viral infection / K. Döhner and B. Sodeik --Nuclear import in viral infections / U.F. Greber and M. Fornerod -- Viral RNA replication in association with cellular membranes / A. Salonen, T. Ahola, and L. Kääriäinen -- Synthesis and quality control of viral membrane proteins / C. Maggioni and I. Braakman -- Receptor modulation in viral replication : HIV, HSV, HHV-8 and HPV : same goal, different techniques to interface with MHC-I antigen presentation / V. Piguet -- Trafficking of viral membrane proteins / R. Byland and M. March.
  • The Neuroanatomy And Neuropsychology Of Declarative And Nondeclarative Memory -- Dynamics Of Hippocampal-cortical Interactions During Memory Consolidation: Insights From Functional Brain Imaging -- From Molecule To Memory System: Genetic Analyses In Drosophila -- Towards A Molecular And Cellular Understanding Of Remote Memory -- Post-activation State: A Critical Rite Of Passage Of Memories -- Reactivation-dependent Amnesia: Disrupting Memory Reconsolidation As A Novel Approach For The Treatment Of Maladaptive Memory Disorders -- The Organizing Principles Of Real-time Memory Encoding: Neural Clique Assemblies And Universal Neural Codes -- Making And Retaining New Memories: The Role Of The Hippocampus In Associative Learning And Memory -- Entorhinal Grid Cells And The Representation Of Space -- The Prefrontal Cortex: Categories, Concepts, And Cognitive Control -- Molecules That Disrupt Memory Circuits In Alzheimer's Disease: The Attack On Synapses By Aβ Oligomers (addls).
  • Why diagnose and treat? -- Evaluating the patient with memory loss -- Alzheimer's disease -- Mild cognitive impairment -- Dementia with lewy bodies (including Parkinson's disease dementia) -- Vascular dementia and vascular cognitive impairment -- Frontotemporal dementia -- Progressive supranuclear palsy -- Corticobasal degeneration -- Normal pressure hydrocephalus -- Creutzfeldt-Jakob disease -- Other disorders -- Goals of treatment -- Cholinesterase inhibitors -- Memantine (Namenda) -- Vitamins, herbs, supplements, and anti-inflammatories -- Future treatments of memory loss -- Non-pharmacological treatment of memory loss -- Evaluating the behavioral and psychological symptoms of dementia -- Caring for and educating the caregiver -- Non-pharmacological treatment of the behavioral and psychological symptoms of dementia -- Pharmacological treatment of the behavioral and psychological symptoms of dementia -- Life adjustments -- Legal and financial issues -- Special issues -- Cognitive test and questionnaire forms, instructions, and normative data --Screening for memory loss -- Our current understanding of memory.
  • Memory reconsolidation 2013
    ScienceDirect
    As little as ten years ago, it was believed that memory went from short to long term via one consolidation practice that made that memory intractable. Since then, research has shown that long term memories can be activated, modified, and reconsolidated in their new form. This research indicates that memories are more dynamic than once believed. And understanding how this process works, and helping people to redefine established memories can be clinically useful, if those memories lead to problems as is the case in post traumatic stress disorder. This book provides a comprehensive overview of research on memory reconsolidation, what this has to say about the formation, storage, and changeabitility of memory, and the potential applications of this research to treating clinical disorders. Presents both neuroscience and psychological research on memory reconsolidation. Discusses what findings mean for understanding memory formation, storage, and retrieval. Includes treatment applications of these findings.
  • Memory T cells 2010
    Springer
    Memory TH1/TH2 cell generation controlled by Schnurri-2 / Toshinori Nakayama and Motoko Y. Kimura -- Transcriptional regulation during CD8 T-cell immune responses / Ivana Munitic ... [et al.] -- The role of interleukin-2 in memory CD8 cell differentiation / Onur Boyman, Jae-Ho Cho and Jonathan Sprent -- The role of inflammation in the generation and maintenance of memory T cells / Noah S. Butler and John T. Harty -- The role of OX40 (CD134) in T-cell memory generation / Andrew D. Weinberg -- The role of precursor frequency in the differentiation of memory T cells : memory by numbers / Amanda L. Marzo, Ryan T. Sowell and Bernadette Scott -- CD8 T-cell memory differentiation during acute and chronic viral infections / Vandana Kalia, Surojit Sarkar and Rafi Ahmed -- Longevity of T-cell memory following acute viral infection / Joshua M. Walker and Mark K. Slifka -- Principles of memory CD8 T-cells generation in relation to protective immunity / Maurizio Zanetti, Paola Castiglioni and Elizabeth Ingulli -- Memory T cells in rhesus macaques / Monica Vaccari and Genoveffa Franchini -- Memory T-cell subsets in parasitic infections / Sara Colpitts and Phillip Scott -- Antigen specific memory T cells and their putative need for the generation of sustained anti-tumor responses / Kory L. Alderson and William J. Murphy -- Memory T-cell responses and survival in human cancer : remember to stay alive / Matthieu Camus and Jérôme Galon -- Analysis of vaccine-induced T cells in humans with cancer / Stefanie L. Slezak ... [et al.] -- Memory T-cell homeostasis and senescence during aging / Sian M. Henson and Arne N. Akbar.
  • MEMS Handbook. 2nd ed. v. 1-3, 2006.
    CRCnetBASE
    v. 2, 2006 CRCnetBASE
    v. 3, 2006 CRCnetBASE
    [v. 1]. MEMS, introduction and fundamentals -- [v. 2]. MEMS, design and fabrication -- [v. 3]. MEMS, applications.
  • Men's health 2013
    Springer
    Men's Health is a concise, didactic compendium that covers three important aspects of male sexual health:- Testosterone Deficiency Syndrome; Premature Ejaculation and Sexually Transmitted Infections (STIs).The chapters that deal with Testosterone Deficiency Syndrome cover the epidemiology of the condition in the local context, the science behind the condition, its clinical presentation and treatment choices.The section on Premature Ejaculation advises the health practitioner on how to investigate this condition and describes the various treatment options available to the patient.The chapters on Sexually Transmitted Infections cover special aspects of the diagnosis, prevention and treatment of STIs occurring in Men which are not normally highlighted in the usual texts on STI management.Written by experts in the field, Men's Health is a valuable and timely resource for urologists, andrologists, endocrinologists as well as other health professionals practicing in these areas.
  • In the last decade, much of the clinical interest in the field of infertility has focused on advancing reproductive techniques and has often under-appreciated the role that male sexuality plays in reproductive problems. Male sexual function is an integral part of reproduction, and the treatment of sexual dysfunction is an important component for any couple seeking fertility. In some cases, treatment of sexual dysfunction may obviate the need for more invasive cures through advanced reproductive techniques. Thanks to recent clinical and scientific advances in male sexual medicine, the management of men's sexual dysfunction is often more effective and less invasive than how it was historically described. Men's Sexual Health and Fertility is the only resource that focuses on the interplay and interconnections between male sexual dysfunction and male factor infertility, gathering insightful data from a panel of experts in male sexual medicine for clinicians who treat couples with fertility issues due to male sexual dysfunction. Chapters discuss advances in the field of men's sexual medicine, including the latest treatment for erectile dysfunction, the most up-to-date understanding of the physiology and pathophysiology of ejaculation, and the growing body of evidence that low testosterone and male infertility are intimately related. As such, this book provides important information in order to be able to better understand the link between sexual dysfunction and infertility and, most importantly, to better treat male sexual dysfunction in the infertile couple.
  • "Meningiomas, by M. Necmettin Pamir, MD, Peter M. Black, MD, PhD, and Rudolf Fahlbusch, MD, presents current and comprehensive guidance on this most common, yet clinically challenging type of brain tumor. Written and edited by the world's most prominent brain tumor neurosurgeons, it helps you to not only determine the type and location of the tumor, but also the most ideal surgical approach to provide your patients with the best outcomes. An extensive collection of surgical photographs covers unique and original cases, while discussions of pre-surgical techniques and approaches emphasize decision making with the help of all imaging modalities and analysis of symptoms and patient history. Expert Consult functionality enhances your reference power with convenient online access to the complete text and illustrations from the book, along with videos that depict surgical techniques in real time."--Publisher's website.
  • Thoroughly discussing the varied elements of meniscal damage and repair, Meniscal Injuries: Management and Surgical Techniques includes the insights and expertise of over 20 leading surgeons and researchers on topics ranging from meniscal anatomy, physical examination, innovative resection and repair techniques, gene therapy, and tissue regeneration. This treatise offers wisdom aimed at assessing true surgical candidates, exploring the intricacies of meniscal composition and function, an overview of meniscal scaffolds and replacements, and patient examination pearls. Also discussed in depth is cutting edge research concerning meniscal repair enhancement, nanofiber technology as a means of meniscal replacement, and biologic agents directed toward chondral protection. All the science presented will direct the sports medicine practitioner to state-of-the-art treatment aimed at knee preservation. Meniscal repair and regeneration is a rapidly evolving science - early attempts at meniscal restoration or repair resulted in short-term gains which often sacrificed long-term joint integrity. Now, the practitioner is afforded numerous means of retaining or restoring meniscal tissue. Breakthroughs in scaffold and allograft replacement, as featured herein, offer the promise of articular cartilage preservation like never before. In addition, tissue regeneration and gene therapy techniques, featured throughout, offer a glimpse into emerging technologies aimed at preserving or replacing meniscal tissue in previously considered hopeless cases. As such, Meniscal Injuries will be an indispensible resource to orthopedic surgeons and sports medicine practitioners interested in providing the absolute most contemporary and evidence-based care to their patients.
  • Meniscal transplantation has become an attractive option in selected patients with incapacitating knee pain. This book discusses all aspects of meniscal transplantation, covering the use of both allografts and meniscal substitutes, including collagen and polyurethane implants. Acknowledged experts in the field review the basic science, explain indications, and describe surgical techniques and the results achieved to date. All the material is up to date, with information on new implants, new techniques, and new surgical approaches. Future trends in the treatment of meniscal lesions are also discussed.
  • Meniscus 2010
    Springer
    Part 1. Basic Science -- Ontogeny-Phylogeny / B. Lebel, C. Tardieu, B. Locker and C. Hulet -- Anatomy / I. D. McDermott, S. D. Masouros, A. M. J. Bull and A. A. Amis -- Histology-Ultrastructure-Biology / P. Verdonk -- Biomechanics / S. D. Masouros, I. D. McDermott, A. M. J. Bull and A. A. Amis -- Synthesis / R. Verdonk -- Part 2. Meniscal Lesions: Classification -- Traumatic Lesions: Stable Knee, ACL Knee / P. Verdonk and P. Vererfve -- Degenerative Lesions-Meniscal Cyst / T. Boyer, H. Dorfmann and A. Podgorski -- Meniscus and Osteoarthritis / N. Pujol and P. Boisrenoult -- Synthesis / P. Beaufils -- Part 3. Preoperative Clinical Examination and Imaging -- Clinical Examination: Standard X-Rays / N. Pujol and P. Boisrenoult -- MRI, MR-arthrography and CT-arthrography / W. C. J. Huysse and K. L. Verstraete -- Bone Scan / S. F. Dye -- Synthesis / P. Beaufils -- Part 4. Technique -- Meniscectomy: Medial-Lateral / K. F. Almqvist, A. A. M. Dhollander, P. Verdonk, Ph. Neyret and R. Verdonk -- Meniscal Repair: Biomechanics / R. Seil and D. Pape -- Meniscal Repair: Technique / F. Jouve, H. Ovadia, N. Pujol and P. Beaufils -- Meniscal Repair: Enhancement of Healing Process / M. Jacobi and R. Peter Jakob -- Meniscal Cysts / C. Hulet, B. Lebel and B. Locker -- Rehabilitation / E. Witvrouw and Y. Thijs -- Synthesis / R. Verdonk -- Part 5. Postoperative Evaluation -- Functional and Objective Scores. Quality of Life / P. Verdonk and R. Verdonk -- Postoperative Imaging: X-Rays, Arthro CT, Arthro MRI / G. Nourissat, C. Pradel and N. Pujol -- Part 6. Results -- Meniscectomy: Global Results-Complications / J.-M. Fayard, H. Pereira, E. Servien, S. Lustig and P. Neyret -- Meniscal Repair: Intra- and Postoperative Complications / M. Katabi, N. Pujol and P. Boisrenoult -- Meniscal Repair: Results / N. Pujol, L. Panarella and P. Beaufils -- Part 7. Indications: Adults -- Traumatic Meniscal Lesions in a Stable Knee: Masterly Neglect, Meniscectomy, Repair / K. F. Almqvist, P. Vansintjan, P. Verdonk and R. Verdonk -- Traumatic Lesions, ACL Knee: Masterly Neglect, Meniscectomy, Repair / O. Charrois, A. Podgorski and P. Beaufils -- Degenerative Meniscal Lesions in a Stable Knee / K. F. Almqvist, P. Vansintjan, P. Verdonk, Y. Bohu and P. Beaufils, et al. -- Lavage, Debridement, and Osteoarthritis / N. Pujol and P. Boisrenoult -- Synthesis / P. Beaufils -- Part 8. Meniscal Lesions in Children -- Classification: Discoid Meniscus, Traumatic Lesions / M. T. Hirschmann and N. F. Friederich -- Discoid Meniscus: Histology / A. Papadopoulos -- Technique of Meniscoplasty and Meniscal Repair in Children / X. Cassard -- Meniscus Lesions in Children-Indications and Results / O. Lorbach, D. Pape and R. Seil -- Synthesis / R. Seil -- Part 9. Post-meniscectomized Knee -- Postoperative Osteonecrosis of the Condyle: Diagnosis and Management / D. Pape, R. Seil and D. Kohn -- Management of Early and Late Failure of Lateral Meniscus / P. Chambat, B. Sonnery-Cottet and C. Guier -- Synthesis / Philippe Beaufils -- Part 10. Meniscal reconstruction- Allograft -- Basic Science / G. von Lewinski and C. J. Wirth -- Organization: Type of Grafts, Conservation, Regulation / T. Schubert, O. Cornu and C. Delloye -- Meniscal Allograft: French Organization / O. Charrois and A. Podgorski -- Open Technique / P. Verdonk and R. Verdonk -- Arthroscopic Technique Without Plugs / J. Bellemans -- Arthroscopic Technique with Bone Plugs / P. Boisrenoult and N. Pujol -- Results and Indications / P. Verdonk, M. Van Laer, M. ELAttar, K. F. Almqvist and R. Verdonk -- Part 11. Meniscal Reconstruction - Substitutes -- Menaflex (TM) Collagen Meniscus Implant: Basic Science / W. G. Rodkey -- Collagen Meniscus Implant: Technique and Results / J. C. Monllau, X. Pelfort and M. Tey -- Actifit, Polyurethane meniscus implant: basic science / J. de Groot -- Polyurethane Meniscus Implant: Technique / R. Verdonk, P. Verdonk and E. L. Heinrichs -- Synthesis / R. Verdonk -- Part 12. The Future -- The Future / P. Verdonk -- Part 13. Conclusion -- General Conclusion / R. Verdonk and P. Beaufils.
  • Normal aging and the menopausal transition : what to expect / N. Santoro, G. Neal-Perry -- Sexuality during menopause : deconstructing the myths / A.H. Clayton, D.V. Hamilton -- Cultural and ethnic influences on the menopause transition /J. Bitzer, J. Alder -- Nonhormonal factors associated with psychiatric morbidity during the menopausal transition and midlife / J.T. Bromberger -- Depression during the perimenopausal transition : what have we learned from epidemiological studies? / S. Ferguson, C.N. Soares, B.L. Harlow -- Thermoregulation and menopause : understanding the basic pathophysiology of vasomotor symptoms / D.C. Deecher -- Hormone dynamics and menopausal symptoms : the clinical role of vasomotor symptoms and sleep disturbances / R.R. Freedman -- Managing depression and anxiety during the menopausal transition and beyond : the window of vulnerability / B.N. Frey, C.N. Soares -- Psychotic disorders and menopause : the untold story / A. Riecher-Ros̈sler -- Hormone therapies and menopause : where do we stand in the post-WHI era? / M.P. Warren, K.E. Titchen, M. Steiner.
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    The contexts of midlife in women / Nada L. Stotland -- Physiology and symptoms of menopause / David A. Baram -- Effects of reproductive hormones and selective estrogen receptor modulators on the central nervous system during menopause / Claudio N. Soares, Meir Steiner, Jennifer Prouty -- Mood disorders, midlife, and reproductive aging / Jamie A. Luff ... [et al.] -- Psychotic illness in women at perimenopause and menopause / Jayashri Kulkarni -- Medical aspects of perimenopause and menopause / Angela M. Cheung -- Gynecologic aspects of perimenopause and menopause / Diana L. Dell -- Beyond menopause : the psychopathology and psychotherapy of older age women / Marta B. Rondon.
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    v. 1. A Synthesis of interdisciplinary research -- v. 2. Research and implications for women's health.
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  • People with mental health conditions comprise a vulnerable group -- Other vulnerable groups have high rates of mental health conditions -- Improving development outcomes: principles and actions -- All development stakeholders have important roles to play -- Conclusion.
  • This book proposes a didactic approach to the different aspects of pain in mental health. The various chapters cover the myths, neurophysiology, perception, measurement and management of pain in mental health. The most common problems, including mood disorders, schizophrenia, anxiety, somatoform disorders, and pervasive developmental disorders, are covered. Each chapter addresses the problem of pain by putting an emphasis on the characteristics of different populations of patients suffering from mental illness. The book helps specialists working in different areas of mental health to appreciate the importance of pain problems in mental health, and also offers avenues for the measurement and treatment of pain in these patients. Mental health and pain are complex issues. They also share certain mutually influential neurophysiological mechanisms, which makes it even more difficult to identify their specific individual characteristics. This duality between the somatic and psychic components can become a pitfall for the specialist in mental health since it can be difficult to disentangle the evolution of a painful condition from the mental illness.
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  • "The World Health Organization launched Project Atlas in 2000. The objective of this project is to collect, compile and disseminate relevant information on mental health resources in countries. The first set of publications from the project appeared in October 2001; these were updated in 2005. These publications have already established themselves as the most authoritative source of such information globally. Responding to the continued need for accurate information, WHO has fully revised and updated the Atlas" -- Page 5.
  • Mental health in adolescents : bipolar disorder / Anne Duffy -- Diagnosis in children and adolescents / Joseph C. Blader -- Benefits of early intervention in young people with bipolar disorder / Aswin Ratheesh & Patrick D McGorry -- Medical comorbidity in youth with bipolar disorder : prevalence and implications for outcome / Muna M. Ali, Danielle S. Cha & Roger S. McIntyre -- Substance use in youth with bipolar disorder / Timothy E. Wilens & Courtney A. Zulauf -- Transitioning from child to adult care / Roberto B. Sassi -- Acute treatment / Ute Lewitzka -- Maintenance treatment / Ute Lewitzka -- State of the art : psychotherapies for individuals at risk, or experiencing a first episode, of bipolar disorder / Martine Vallarino and Jan Scott -- The implications of manic-like symptoms for subsequent psychopathology / Anne Duffy -- Multiple choice questions : answers.
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    v. 1. Aponte, H. J. et al. Genetics, family, and community studies.
  • This book tackles the issue of mental health legislation in South Asia. The first of its kind, it addresses an issue that is necessary for protecting the rights of people with mental disorders and serves as an essential text for reinforcing mental health policy in South Asia. it is a timely addition to our global understanding of mental health and how different regions address it.Asia is by far the largest continent in the world in terms of area with population exceeding 3.5 billion and has dozens of cultures, religions, languages and ethnic groups. As a result of its highly varied political systems, Asia also spawns a wide variety of health care systems including mental health care systems, often based on historical roots and at times colonial heritages. The people who suffer from mental or neurological disorders in the continent form a vulnerable section of society and often face stigma, discrimination and marginalization in all societies, and this increases the likelihood that their human rights will be violated
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  • Past, Present and Future Policy Landscape for Technology in Public Mental Health Care -- Electronic Health Records Technology: Policy and Realities -- Leading Health IT Optimization: A Next Frontier -- Computer aided Psychotherapy Technologies -- Cognitive Assessment and Enhancement Technologies -- Digital platform and technology innovation in treatment of substance use disorders -- Technology and Adolescent Behavioral Health Care -- An Overview of Practicing High Quality Telepsychiatry -- Virtual Reality Technologies -- Social Media Technologies -- Technology Tools supportive of DSM-V: An Overview -- Summary and Look Forward.
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    The politics of mental welfare : fresh perspectives on the history of institutionalized care for the mentally ill and disabled / Pamela Dale and Joseph Melling -- Workhouse care of the insane, 1845-1890 / Elaine Murphy -- Needs and desires in the care of paper lunatics : admissions to Worcester Asylum, 1852-1872 / Frank Crompton -- 'Buried alive by her friends' : asylum narratives and the English governess, 1845-1914 / Joseph Melling -- Separatism and exclusion : women in psychiatry, 1900-1950 / Louise Westwood -- Family, gender and class in psychiatric patient care during the 1930s : the 1930 Mental Treatment Act and the Devon Mental Hospital / David Pearce -- The 'manufacture' of mental defectives : increased in Scotland, 1857-1939 / Matt Egan -- Tension in the voluntary-statutory alliance : 'lay professionals' and the planning and delivery of mental deficiency services, 1917-1945 / Pamela Dale -- 'A satisfactory job is the best psychotherapist' : employment and mental health, 1939-60 / Vicky Long -- Inside the walls of the hostel, 1940-1974 / John Welshman -- Landmarks in the care of the mentally disordered.
  • Mental measurements yearbook
    Ovid, Limited to 4 simultaneous users
    Test reviews online Ovid, Limited to 4 simultaneous users
  • Mental models, sentential reasoning, and illusory inferences / P.N. Johnson-Laird -- Interaction of knowledge and working memory in reasoning about relations / A. Vandierendonck, V. Dierckx & H. Van der Beken -- Mental models in learning situations / N.M. Seel -- Resolving valid multiple model inferences activates a left hemisphere network / R.L. Waechter & V. Goel -- A neuro-cognitive theory of relational reasoning with mental models and visual images / M. Knauff -- Pictures, perception, and mental models / K. Rehkämper -- Emotion, decision, and mehtal models / M. Pauen -- Language processing : construction of mental models or more? / B. Hemforth & L. Konieczny -- Visual imagery, mental models, and reasoning / V. Gottschling -- Mental models as objectual representations / C. Held -- The perceptual nature of mental models / G. Vosgerau.
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    Introduction to mentoring -- Mentoring internships -- Mentoring and library school assignments -- Should I become a librarian? -- Developing the new librarian in the work place -- Mentoring for promotion -- Volunteers in libraries and librarians as volunteers -- Mentoring librarians electronically -- Other kinds of mentoring in the library field -- Conclusions.
  • What is the evidence for mentorship? -- What are the characteristics and behaviors of effective mentors and mentees? -- How can you initiate mentorship? -- Some effective mentoring strategies and tactics : part 1, mentorship meetings, priority setting, and time-management -- Some effective mentoring strategies and tactics : part 2, protecting mentees from dys-opportunities -- Some effective mentoring strategies and tactics : part 3, mentoring for knowledge generation -- Some effective mentoring strategies and tactics : part 4, mentoring for knowledge dissemination -- Some effective mentoring strategies and tactics : part 5, mentoring for promotion, protection, and job prospects -- How can you assess, diagnose and treat mentorship that is in trouble? -- How can you initiate and maintain a mentorship progam? -- How can you evaluate the impact of a mentorship program? -- How can you scale up and sustain a mentorship program?.
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  • Merck Veterinary manual Latest ed. only
  • Part I: Basic Science and Epidemiology -- Basic Science of the Merkel Cell -- Epidemiology and Genetics (Including High Risk Patients, Polyomavirus, Prognostic Factors) -- Part II: Diagnosis -- Clinical Diagnosis -- Staging -- Histopathologic Diagnosis -- Part III: Therapy -- Local Excision (Primary, Recurrent Disease) -- Lymph Node Procedures of the Head and Neck -- Lymph Node Procedures of the Trunk and Extremities -- Radiation Therapy (Primary and Recurrent Disease) -- Chemotherapy (Primary and Recurrent Disease) -- Treatment Algorithm -- Part IV: Expert Opinions and Future Directions -- Case Study A: Multiply Recurrent Merkel Cell Carcinoma -- Case Study B: Radiation Monotherapy for Extensive Local and In-Transit Merkel Cell Carcinoma -- Case Study C: Complete Spontaneous Regression of Merkel Cell Carcinoma Metastatic to the Liver -- Case Study D: Evaluation of Multiple Merkel Cell Carcinomas in a Single Patient -- Case Study E: Multidisciplinary Management of Merkel Cell Carcinoma -- Track and Attack: Emerging Prognostic and Therapeutic Approaches.
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    Signs and symptoms in neurologic diagnosis: approach to the patient -- Delirium and confusion -- Memory loss, behavioral changes and dementia -- Aphasia, apraxia, and agnosia -- Syncope, seizures and their mimics -- Coma -- Headache -- Diagnosis of pain and paresthesias -- Dizziness, vertigo, and hearing loss -- Impaired vision -- Involuntary movements -- Syndromes caused by weak muscles -- Gait disorders -- CT and MRI -- Electroencephalography and evoked potentials -- Electromyography, nerve conduction studies, and and magnetic stimulation -- Autonomic testing -- Neurovascular imaging -- Endovascular neuroradiology -- Lumbar puncture and cerebrospinal fluid examination -- Muscle and nerve biopsy -- Neuropsychological evaluation -- DNA diagnosis -- Bacterial infections -- Focal infections -- Viral infections and postviral syndromes -- Human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) -- Fungal infections -- Neurosarcoidosis -- Neurosyphilis -- Leptospirosis -- Lyme disease -- Parasitic infections -- Bacterial toxins -- Prion diseases -- Whipple disease -- Pathogenesis, classification, and epidemiology of cerebrovascular disease -- Examination of the patient with cerebrovascular disease -- Transient ischemic attack -- Cerebral infarction -- Intracerebral hemorrhage -- Genetics of stroke -- Other cerebrovascular syndromes -- Differential diagnosis of stroke -- Stroke in children -- Treatment and prevention of stroke -- Subarachnoid hemorrhage -- Cerebral venous and sinus thrombosis -- Vascular disease of the spinal cord -- Vasculitis -- Susac syndrome -- Vascular tumors and malformations -- Hydrocephalus -- Normal pressure hydrocephalus (NPH) -- Brain edema and disorders of intracranial pressure -- Superficial siderosis and intracerebral hypotension -- Hyperosmolar syndromes -- General considerations -- Tumors of the skull and cranial nerves -- Tumors of the meninges -- Gliomas -- Lymphomas -- Pineal region tumors -- Tumors of the pituitary gland -- Congenital and childhood tumors -- Metastatic tumors -- Spinal tumors -- Paraneoplastic syndromes -- Complications of cancer chemotherapy -- Head injury -- Spine injury -- Cranial and peripheral nerve lesions -- Complex regional pain syndrome -- Radiation injury -- Electrical and lightning injury -- Decompression sickness -- Intervertebral dics and radiculopathy -- Cervical spondylotic myelopathy -- Thoracic outlet syndrome -- Hereditary and acquired spastic paraplegia -- Syringomyelia -- Neonatal neurology -- Floppy infant syndrome -- Disorders of motor and mental development -- Autism spectrum disorders -- Laurence-Moon-Biedl syndrome -- Cerebral and spinal malformations -- Chromosomal diseases -- Marcus Gunn -- Möbius syndrome -- Disorders of amino acid metabolism -- Disorders of purine and pyrimidine metabolism -- Lysosomal and other storage diseases -- Disorders of carbohydrate metabolism -- Glucose transporter type 1 deficiency syndrome -- Disorders of DNA maintenance, transcription, and translation -- Hyperammonemia -- Peroxisomal diseases: adrenoleukodystrophy, zellweger syndrome, and refsum disease -- Organic acidurias -- Disorders of metal metabolism -- Acute intermittent porphyria -- Neurologic syndromes with acanthocytes -- Cerebral degenerations of childhood -- Diffuse sclerosis and vanishing white matter disease -- Mitochondrial encephalomyopathies: diseases of mitochondrial DNA -- Leber hereditary optic neuropathy -- Mitochondrial diseases with mutations of nuclear DNA -- Neurofibromatosis -- Tuberous sclerosis complex -- Encephalotrigeminal angiomatosis -- Incontinentia pigmenti -- General considerations -- Alzheimer disease -- Frontotemporal dementia -- Lewy body dementias -- Huntington disease -- Choreas -- Myoclonus -- Gilles de la tourette syndrome -- Dystonia -- Essential tremor -- Parkinson disease -- Parkinson-plus syndromes -- Paroxysmal dyskinesias -- Tradive dyskinesia and other neuroleptic-induced syndromes -- Autosomal recessive ataxias -- Autosomal dominant ataxias -- Amyotrophic lateral sclerosis, progressive muscular atrophy, and primary lateral sclerosis -- Kennedy disease -- Spinal muscular atrophies of childhood -- Monomelic muscular atrophy -- General considerations -- The inherited peripheral neuropathies -- Acquired neuropathies -- Neuropathic pain -- Myasthenia gravis -- Lambert-Eaton syndrome -- Botulism and antibiotic-induced neuromuscular disorders -- Critical illness myopathy and neuropathy -- Identifying disorders of the motor unit -- Progressive muscular dystrophies -- Familial periodic paralysis -- Congenital disorders of muslce -- Myoglobinuria -- Muscle cramps and stiffness -- Dermatomyositis -- Polymyositis, inclusion body myositis, and related myopathies -- Myositis ossificans -- Multiple sclerosis -- Neuromyelitis optica -- Marchiafava-Bignami disease -- Central pontine myelinolysis -- Epilepsy -- Febrile seizures -- Primary and secondary headaches -- Transient global amnesia -- Ménière syndrome -- Sleep disorders -- Neurogenic orthostatic hypotension, autonomic failure, and autonomic neuropathy -- Familial dysautonomia -- Endocrine diseases -- Hematologic and related diseases -- Hepatic disease -- Cerebral complications of cardiac surgery -- Bone disease -- Renal disease -- Respiratory support for neurologic diseases -- Nutritional disorders: malnutrition, malabsorption, and B₁₂ and other vitamin deficiency -- Hypertrophic pachymeningitis -- Neurologic disease during pregnancy -- Hashimoto encephalopathy -- Schizophrenia -- Mood disorders -- Anxiety disorders -- Somatoform disorders -- Alcoholism -- Drug dependence -- Iatrogenic disease -- Occupational and environmental neurotoxicology -- HIV, fetal alcohol and drug effects, and the battered child -- Falls in the elderly -- Neurologic rehabilitation -- End-of-life issues in neurology.
  • Mesenchymal Stem Cells or Multipotent Mesenchymal Stromal Cells (collectively referred to as MSCs) are currently being tested in a number of clinical trials for various diseases including graft-versus-host disease, Crohn's disease, myocardial infarction, stroke, diabetes, cartilage defects, and many others. The increasing number of clinical trials globally indicates the likely therapeutic potential of this specialized adult stem cell. Over the last decade, there has been tremendous progress towards understanding an MSC's phenotype, expansion features in culture, differentiation ability and global gene and protein expression profiles. Despite the enormous progress and data accrual at the molecular and cellular levels, several questions remain as to the utility of MSCs for clinical applications. Mesenchymal Stem Cell Therapy is a comprehensive collection of information comprised of both basic and pre-clinical biological studies as well as current advances in clinical applications within the MSC therapy field. This text is a resource for both the basic life science and cell therapy researchers and includes a spectrum of review chapters from top experts in the field discussing clinical scale culture, regulatory issues, genetic engineering, disease specific applications and others.
  • Part I. Isolation of human multipotential stromal cells from bone marrow and adipose tissue. Isolation and culture of bone marrow-derived human multipotent stromal cells (hMSCs) / Margaret Wolfe ... [et al.]. Mesenchymal stem cells from adult bone marrow / Mark F. Pittenger. A method to isolate and purify human bone marrow stromal stem cells / Stan Gronthos and Andrew C. W. Zannettino. Adipose-derived stem cells / John K. Fraser ... [et al.]. Isolation of human adipose-derived stem cells from biopsies and liposuction specimens / Severine G. Dubois ... [et al.] -- Part II. Manipulation of human multipotential stromal cells. Colony forming unit assays for MSCs / Radhika Pochampally. Differentiation and characterization of human MSCs / Roxanne L. Reger, Alan H. Tucker, and Margaret R. Wolfe. Freezing harvested hMSCs and recovery of hMSCs from frozen vials for subsequent expansion, analysis, and experimentation / Roxanne L. Reger and Margaret R. Wolfe. Gene expression analysis at the single cell level using the human bone marrow stromal cell as a model : sample preparation methods / Beerelli Seshi. Assays of MSCs with microarrays / Joni Yöstalo, Radhika Pochampally, and Darwin J. Prockop. Gene delivery to mesenchymal stem cells / Reza Izadpanah and Bruce A. Bunnell -- Part III. Isolation and characterization of murine multipotential stromal cells from bone marrow. Isolation of mesenchymal stem cells from murine bone marrow by immunodepletion / Donald G. Phinney.
  • 1. Mesenchymal stromal cells in regressive medicine: a perspective / Peiman Hematti and Armand Keating -- 2. MSCs: changing hypotheses, paradigms, and controversies on mechanisms of action in repairing tissues / Darwin J. Prockop and Roxanne L. Reger -- 3. MSCs: the need to rethink / Paolo Bianco and Pamela G. Robey -- 4. Characterization of MSCs: from early studies to the present / Mark F. Pittenger -- 5. MSCs as therapeutics / Arnold I. Caplan -- 6. MSC niche for hematopoiesis / Daniel Lucas, Sandra Pinhol and Paul S. Frenette -- 7. Immunomodulatory properties of MSCs / Maria Ester Bernardo, Lynne M. Ball, Franco Locatelli and Willem E. Fibbe -- 8. MSCs and inmate immune responses: a balancing act / Krisztián Németh and Éva Mezey -- 9. MSCs: paracrine effects / Siddiraju V. Boregowda and Donald G. Phinney -- 10. Cross-talk between MSCs and their environments / Thomas P. Lozito and Rocky S. Tuan -- 11. Human MSCs from bone marrow, umbilical cord blood, and adipose tissue: all the same? / Patrick Wuchter and Anthony D. Ho -- 12. MSCs in solid tumors and hematological malignancies: from basic biology to therapeutic applications / Rodrigo Jaeamo, Erika Spaeth, Venkata Battula, Frank Marini and Michael Andreeff -- 13. MSC studies in large-animal models / Bruce A. Bunnell, Christine Gagliardi, and Maria Isabel Ribeiro Dias -- 14. Defining the potential of MSCs with a prenatal large animal model / Grac̦a Almeida-Porada, Christopher D. Orada and Esmail D. Zanjani -- 15. Bench-to-bedside development of MSC therapies: a multidisciplinary approach / Sowmya Viswanathan and Elizabeth J. Read -- 16. cGMP production of MSCs / Derek J. Hei and David H. McKenna, Jr. -- 17. MSCs: the US regulatory perspective / Adrian P. Gee -- 18. MSCs: clinical applications and European regulatory aspects / Jens Reinhardt, Egbert Flory, Isabel Büttel, Christa Schröder, Stefan Fricke, Vladan Vucinic, Michael Cross and Dietger Niederwieser -- 19. Stem cell treatments around the World: boon or bane?/ Alok Srivastava -- 20. Safety issues in MSC therapy / Minoo Battiwalla and A. John Barrett -- 21. In vivo imaging of MSCs / Jeff W.M. Bulte -- 22. National Heart, Lung and Blood Institute support of cellular therapies regenerative medicine / Traci Heath Mondoro and John Thomas -- 23. MSC therapy of inborn errors / Edwin M. Horwitz -- 24. MSCs for enhancement of hematopoietic progenitor cell engraftment and poor graft function / Paolo F. Caimi and Hillard M. Lazarus -- 25. MSCs ro graft-versus-host disease / Jakub Tolar, Katarina Le Blanc and Bruce R. Blazar -- 26. MSCs in pediatric hematopoietic stem cell transplantation / Lynne M. Ball, Maria Ester Bernardo, Franco Locatelli and R. Maarten Egeler -- 27. MSC for ex vivo expansion of umbilical cord blood cells / Ian K. McNiece, Simon N. Robinson, and Elizabeth J. Shpall -- 28. MSCs for autoimmune diseases / Alan Tyndall and Chiara Bocelli -- 29. MSCs for induction of solid organ allograft acceptance / Marc Dahlke, Philipp Renner and Elke Eggenhofer -- 30. MSCc for gastrointestinal disorders / Maria Ester Bernardo, Angela Maria Cometa and Franco Locatelli -- 31. MSCs for cardiac repair / Amish N. Raval and Timothy A. Hacker -- 32. MSCs for treatment of acute lung injury / Vladimir B. Serikov, Anna Krasnodembskaya, Jae Wood Lee, Marlowe W. Eldridge and Michael A. Matthay -- 33. MSCs for diabetes / Luca Inverardi, Giacomo Lanzoni, Juan Dominguez-Bendala and Camillo Ricordi -- 34. MSCs for renal repair / Anna M. Gooch and Christof Westenfelder -- 35. MSCs for the treatment of stroke, spinal cord injury, and traumatic brain injury: from bench work to clinical trials / Bing Yang, Ramy El Khoury, and Sean I. Savitz -- 36. MSCs in reconstructive surgery / Summer E. Hanson and Michael L. Bentz -- 37. MSCs in orthopedic surgery / Summer E. Hanson and Nicholas H. Maassen -- 30. Adipose tissue-derived MSCs: moving to the clinic / Pedro P. Carvalho, Manuela E. Gomes, Rui L. Reis and Jeffrey M. Gimble.
  • This book represents the first comprehensive textbook devoted to the standard of care, current guidelines and innovations in the field of mesenteric vascular disease. The book reviews imaging modalities, diagnostic work up, physiologic tests, traditional open surgical techniques and novel endovascular approaches. Technical aspects of both open surgical and endovascular techniques are provided by experts in the field, with illustrations and photographs of key steps for each type of procedure. Results of epidemiologic studies and national databases are summarized, as well as large institutional experiences. An evidence-based approach is used for recommendations regarding best therapies. Diagnostic approaches including imaging and novel physiologic tests, including gastric tonometry and oxygen light spectroscopy are also covered. Mesenteric Vascular Disease: Current Therapy will serve as a very useful resource for clinicians, surgeons, interventionalists, gastroenterologists and researchers dealing with and interested in mesenteric vascular diseases.
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    "Using key canonical science fiction narratives, Mesmerists, Monsters, and Machines examines the intersection of the literary and scientific cultures of the nineteenth century. In this approach to the study of early science fiction, author Martin Willis maintains that science fiction was just as important in defining the culture of the nineteenth century as other critics maintain it was in shaping the twentieth century." "Mesmerists, Monsters, and Machines interrogates the cultural implications of scientific development as articulated, challenged, and reformulated by science fiction. Each chapter demonstrates that both science and fiction were vital parts of a culture of imaginative and empirical practices that were continually reacting to, arguing with, and influencing one another throughout the nineteenth century. In a narrative that cites classic science fiction texts, Willis establishes a timeline for the reader so that the cultural significance of science fiction is understood and its complexity and relevance to the nineteenth century is demonstrated." "Those interested in nineteenth-century history and literature, cultural studies, the history of science, and science fiction will welcome this addition to the scholarship."--Book jacket.
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  • Pt. 0. Introductory Material -- 1. brief introduction to meta-analysis, genetics, and genomics / Darlene R. Goldstein and Rudy Guerra -- Pt I. Similar Data Types I: Genotype Data -- 2. Combining information across genome-wide linkage scans / Carol J. Etzel and Tracy J. Costello -- 3. Genome search meta-analysis (GSMA): a nonparametric method for meta-analysis of genome-wide linkage studies / Cathryn M. Lewis -- 4. Heterogeneity in meta-analysis of quantitative trait linkage studies / Hans C. van Houwelingen and Jeremie J. P. Lebrec -- 5. empirical Bayesian framework for QTL genome-wide scans / Kui Zhang ... [et al.] -- Pt. II. Similar Data Types II: Gene Expression Data -- 6. Composite hypothesis testing: an approach built on intersection-union tests and Bayesian posterior probabilities / Stephen Erickson, Kyoungmi Kim and David B. Allison -- 7. Frequentist and Bayesian error pooling methods for enhancing statistical power in small sample microarray data analysis / Jae K. Lee, Hyung Jun Cho and Michael O'Connell -- 8. Significance testing for small microarray experiments / Charles Kooperberg ... [et al.] -- 9. Comparison of meta-analysis to combined analysis of a replicated microarray study / Darlene R. Goldstein ... [et al.] -- 10. Alternative probe set definitions for combining microarray data across studies using different versions of Affymetrix oligonucleotide arrays / Jeffrey S. Morris ... [et al.] -- 11. Gene ontology-based meta-analysis of genome-scale experiments / Chad A. Shaw -- Pt. III. Combining Different Data Types -- 12. Combining genomic data in human studies / Debashis Ghosh, Daniel Rhodes and Arul Chinnaiyan -- 13. overview of statistical approaches for expression trait loci mapping / Christina Kendziorski and Meng Chen -- 14. Incorporating GO annotation information in expression trait loci mapping / J. Blair Christian and Rudy Guerra -- 15. misclassification model for inferring transcriptional regulatory networks / Ning Sun and Hongyu Zhao -- 16. Data integration for the study of protein interactions / Fengzhu Sun ... [et al.] -- 17. Gene trees, species trees, and species networks / Luay Nakhleh, Derek Ruths and Hideki Innan.
  • Principles of human energy metabolism -- Intermediary metabolsim of carbohydrate, protein, and fat -- Adipose tissue development, structure and function -- Adipokines in health and disease -- Neural control of feeding and energy homeostasis -- Gastrointestinal hormones and obesity -- Genes and human obesity -- Classical hormones linked to obesity -- Inflammation and adipose dysfunction -- Insulin resistance in the metabolic syndrome -- Pancreatic islet €-cell failure in obesity -- Non-alcoholic fatty liver disease -- Sleep, circadian rhytms and metabolism -- Obesity and cardiac dysfunction -- Atherogenic lipid metabolism in obesity -- Gut microbes, immunity, and metabolism -- Impact of obesity on female reproductive health -- Lessons from HIV lipodystrophy -- Principles of obesity therapy.
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  • Metabolic syndrome and schizophrenia : is inflammation the cause? / Leonard, B.E. -- Insulin resistance in bipolar women : effects of mood-stabilizing drugs / Vemuri, M. ... [et al.] -- Obesity and mental illness / Citrome, L.; Vreeland, B. -- Glucose abnormalities in schizophrenia, bipolar and major depressive disorders / Bushe, C. -- Screening for diabetes and cardiovascular risk factors in people with serious mental illness / Holt, R.I.G.; Peveler, R.C. -- Stress axis dysfunction : a common finding in schizophrenia and the metabolic syndrome? / Afzal, A.; Thakore, J. -- Metabolic syndrome in psychiatric inpatients treated for depression / Goethe, J.W.; Szarek, B.L.; Caley, C.F. -- Hyperprolactinaemia associated with antipsychotic medications / Fitzgerald, P.; Dinan, T.G. -- Impact of hyperprolactinaemia on the general health of patients with schizophrenia / Wildgust, H.J.; Kohen, D.
  • Acid amides -- Amidines, guanidines, and hydrazines -- Amino acids: phosphinic acids -- Anilines and nitrobenzenes -- Aryloxy acids -- Biphenyl ethers -- Carbamates -- Dithio- and thiolcarbamates -- Halogenated aliphatics -- Halogenated aromatics -- Five-membered heterocycles -- Five-membered heterocycles (fused) -- Six-/more membered heterocycles -- Six-/more membered heterocycles (fused) -- Imides -- Natural products -- Organophosphorous compounds -- Oximes -- Phenylureas and related compounds -- Phosphono amino acids and related compounds -- Pyrethroids -- Sulfonylureas -- Triazines and related compounds -- Miscellaneous.
  • v. 2 CRCnetBASE
    [v. 1.] Fundamentals -- [v. 2.] Tools and applications.
  • Origins of metabolic profiling / Arthur B. Robinson and Noah E. Robinson -- Amino acid profiling for the diagnosis of inborn errors of metabolism / Monique Piraud ... [et al.] -- Acylcarnitines : analysis in plasma and whole blood using tandem mass spectrometry / David S. Millington and Robert D. Stevens -- Analysis of organic acids and acylglycines for the diagnosis of related inborn errors or metabolism by GC- and HPLC-MS / Giancarlo la Marca and Cristiano Rizzo -- HPLC analysis for the clinical-biochemical diagnosis of inborn errors of metabolism of purines and pyrimidines / Giuseppe Lazzarino ... [et al.] -- Bile acid analysis in various biological samples using ultra performance liquid chromatography/electrospray ionization-mass spectrometry (UPLC/ESI-MS) / Masahito Hagio, Megumi Matsumoto, and Satoshi Ishizuka -- Analysis of glycolytic intermediates with ion chromatography- and gas chromatography-mass spectrometry / Jan C. van Dam, Cor Ras, and Angela ten Pierick -- Analysis of the citric acid cycle intermediates using gas chromatography-mass spectrometry / Rajan S. Kombu, Henri Brunengraber, and Michelle A. Puchowicz -- Quantification of pentose phosphate pathway (PPP) metabolites by liquid chromatography-mass spectrometry (LC-MS) / Amber Jannasch, Miroslav Sedlak, and Jiri Adamec -- High-performance liquid chromatography-mass spectrometry (HPLC-MS)-based drug metabolite profiling / Ian D. Wilson -- Gas chromatography-mass spectrometry (GC-MS)-based metabolomics / Antonia Garcia and Coral Barbas -- Use of two-dimensional gas chromatography-time-of-flight mass spectrometry (GCxGC-TOF-MS) for metabolomic analysis of polar metabolites / Kimberly Ralston-Hooper ... [et al.] -- LC-MS-based metabolomics / Sunil Bajad and Vladimir Shulaev -- Capillary electrophoresis-electrospray ionization-mass spectrometry (CE-ESI-MS)-based metabolomics / Philip Britz-McKibbin -- Liquid chromatography-mass spectrometry (LC-MS)-based lipidomics for studies of body fluids and tissues / Heli Nygren ... [et al.] -- Electrospray ionization tandem mass spectrometry (ESI-MS/MS)- based shotgun lipidomics / Giorgis Isaac -- Processing and analysis of GC/LC-MS based metabolomics data / Elizabeth Want and Perrine Masson -- Nuclear magnetic resonance (NMR)-based drug metabolite profiling / Eva M. Lenz -- Nuclear magnetic resonance (NMR)-based metabolomics / Hector C. Keun and Toby J. Athersuch -- Slow magic angle sample spinning : a non- or minimally invasive method for high-resolution ¹H nuclear magnetic resonance (NMR) metabolic profiling / Jian Zhi Hu -- Processing and modeling of nuclear magnetic resonance (NMR) metabolic profiles / Timothy M. D. Ebbels, John C. Lindon, and Muireann Coen.
  • The metabolic syndrome is a cluster of common pathologies: abdominal obesity linked to an excess of visceral fat, insulin resistance, dyslipidemia and hypertension. At the molecular level, metabolic syndrome is accompanied not only by dysregulation in the expression of adipokines, cytokines, and chemokines but also by alterations in insulin and leptin signaling, oxidative stress, and chronic low grade inflammation. These changes affect immune responses and mediate chronic inflammation leading to alterations in the hypothalamic 'bodyweight/appetite/satiety set point'. It is becoming increasingly evident that metabolic syndrome is a risk factor for neurological disorders such as stroke, depression, and Alzheimer disease (AD). Family history, age, environmental and lifestyle factors (diet and physical inactivity, and exposure to toxins) are closely associated with predisposition for the development of metabolic syndrome as well as neurological disorders. The incidences of stroke are 2 to 4-fold higher in patients with metabolic syndrome and cardiovascular diseases compared to normal subjects of the same age. Similarly, patients with metabolic syndrome have a 2 to 3-fold increased risk for developing dementia and AD. Metabolic syndrome doubles the risk of depression. The molecular mechanism underlying the mirror relationship between metabolic syndrome and neurological disorders is not fully understood. However, biochemical alterations observed in metabolic syndrome like induction of chronic inflammation and oxidative stress, impairment of endothelial cell function, induction of insulin and leptin resistance, hyperglycemia-related increase in advanced glycation end-products, and micro-vascular injury may represent a pathological bridge between metabolic syndrome and neurological disorders. It is hoped that Metabolic Syndrome: An important risk factor for stroke, Alzheimer disease, and depression will be useful to postgraduate students, faculty, research scientists, pharmacologists, nutritionists, and physicians, who are curious about the molecular mechanisms that link metabolic syndrome with stroke, Alzheimer disease, and depression.
  • "Metabolic Syndrome and Neurological Disorders brings together information on the cluster of common pathologies which cause metabolic syndrome - abdominal obesity linked to an excess of visceral fat, insulin resistance, dyslipidemia and hypertension - to provide a comprehensive and cutting edge exploration of the link between metabolic syndrome and neurological disorders. Metabolic syndrome is recognized to play a role in neurological disorders such as stroke, Alzheimer's disease, and depression. For the first time in book form, Metabolic Syndrome and Neurological Disorders covers the molecular mechanisms thought to underlie this mirror relationship, as well as how lifestyle and other factors such as oxidative stress and inflammation may play a role in the disease. Grounded in a series of epidemiological studies of metabolic-cognitive syndrome, this book will be a valuable reference for researchers, dietitians, nutritionists, and physicians"--Provided by publisher.
  • Definitions and prevalence -- How do we get fat?: an epidemiological and metabolic approach -- Costs, pathology, and health risks of obesity and the metabolic syndrome -- Natural history of obesity: differential diagnosis, clinical types, and age-related changes -- Evaluation, prevention, and introduction to treatment -- Diet -- Behavior modification -- Physical activity and exercise in the obese -- Pharmacological treatment of the overweight patient -- Should we treat the metabolic syndrome or its components? -- Surgical treatment for the overweight patient.
  • Definitions and clinical aspects. Definitions -- Hypothalamic obesity in children -- Causes. Genetics of obesity in childhood and adolescence -- Nutrition -- Sedentary lifestyle -- Socio-economic aspects -- Consequences. Carbohydrate metabolism -- Orthopaedic aspects of obesity in children and adults -- Urogenital complications: renal disease, urolithiasis and lower urinary tract symptoms -- Influences of childhood obesity on pubertal development -- Social aspects and prevention. Urban living conditions: the relation between neighborhood characteristics and obesity in children and adolescents -- Metabolic syndrome and the 'Western diet': science and politics -- An economic perspective on childhood obesity -- Prevention of childhood and adolescent obesity and its barriers -- E-health in overweight and obesity prevention -- Obesity management. Obesity treatment programmes -- Adolescent bariatric surgery: current status in an evolving field -- Beyond weight loss: experiences and insights related to working effectively with families and operating within the health care system to manage pediatric obesity.
  • Part 1. Metabolic Syndrome - Past and Future -- Metabolic Syndrome - Past and Future : An Introduction to the Features of This Book / Barbara Caleen Hansen, Rosemary Peternel and George A. Bray -- I. Epidemiology And Clinical Treatment: Issues In Defining And Treating The Metabolic Syndrome -- Metabolic Syndrome : To Be or Not to Be? / Gerald M. Reaven -- The Role of Obesity in Insulin Resistance : Epidemiological and Metabolic Aspects / James B. Meigs -- Treatment of the Metabolic Syndrome with Weight Loss, Exercise, Hormones, and Surgery / George A. Bray -- Insulin Resistance, Metabolic Syndrome, and Cardiovascular Disease : An Epidemiological Perspective / Earl S. Ford and Simin Liu -- The Sympatho-Adrenal System in the Metabolic Syndrome / Lewis Landsberg -- II. Endothelial Function, Inflammation, and Dyslipidemia -- Insulin Action and Endothelial Function / Kieren J. Mather, Alain Baron and Michael J. Quon -- Macro- and Microvascular Disease in an Insulin-Resistant Pre-Diabetic Animal Model : The JCR:LA-cp Rat / James C. Russell and Spencer D. Proctor -- High-Sensitivity C-Reactive Protein and the Metabolic Syndrome / Yiqing Song, Simin Liu and Joann E. Manson -- Insulin Signaling in Adipocytes and the Role of Inflammation / Christian X. Andersson, Ann Hammarstedt, Per-Anders Jansson and Ulf Smith -- Insulin Resistance and Dyslipidemia / Tina J. Chahil, Gissette Reyes and Henry N. Ginsberg -- III. Insulin - Secretion and Action: Underlying Mechanisms of the Metabolic Syndrome -- Pancreatic Islet Pathophysiology and Pathology in Obesity / Anne Clark, Jenni Moffitt, Lianne Van De Laar, Katherine Pinnick and Farhina Sayyed -- Glucagon-like Peptides and Insulin Sensitivity / Jens Juul Holst and Filip Krag Knop -- The Relationship Between the Insulin Receptor Substrates and Metabolic Disease / Morris F. White -- Insulin Resistance and Inhibitors of the Insulin Receptor Tyrosine Kinase / Jack F. Youngren -- Fat Feeding and Muscle Fat Deposition Eliciting Insulin Resistance : An Update / E. W. Kraegen, G. J. Cooney, Jiming M. Ye and Stuart M. Furler -- Alterations in Atypical Protein Kinase C Activation in Insulin Resistance Syndromes / Robert V. Farese -- The Liver, Glucose Homeostasis, and Insulin Action in Type 2 Diabetes Mellitus / Jerry Radziuk and Susan Pye -- Chronomics of the Metabolic Syndrome / Barbara Caleen Hansen.
  • Metabolic syndrome is a common syndrome affecting about 20% of the adult population in Europe, and the prevalence is likely similar in other industrialised countries worldwide. It is mainly caused by the western lifestyle, which tends to produce abdominal obesity, but a genetic predisposition also plays a part. This syndrome, which is linked to leisure lifestyles and overeating/obesity, can develop into type 2 diabetes, cardiovascular disease and cancer. Therefore, proper treatment and prevention are essential. This book discusses lifestyle intervention and treatment, specifically with pharmacological compounds, in order to formulate a strategy for treating the metabolic syndrome in daily practice.
  • Metabolism and disease 2011
    Cold Spring Harb Lab Press
    "The Symposium aimed to integrate a very broad field of investigative effort, bringing together advances in our understanding of energy intake, consumption, and storage (diet, exercise, and fat), oxygen regulation and hypoxia, circadian rhythms, and life span/aging. The Symposium explored metabolism at molecular (gene expression, posttranslational modifications, protein turnover, cofactors and integrators, hormones, and signals), organellar (mitochondria), cellular, organ system (cardiovascular, bone), and organismal (timing and life span) scales. Diseases impacted by metabolic imbalance or dysregulation that were covered in detail included diabetes, obesity, metabolic syndrome, and cancer. New and emerging technologies were presented for simultaneous monitoring of hundreds of metabolites that allow for sophisticated sampling of the metabolic state of cells. Because the Symposium covered such a broad field, by necessity much excellent work could not be included, and instead, the Proceedings should be viewed as a necessarily eclectic collection of some of the most interesting and stimulating work that came to the organizers' attention during the 18 months before the meeting"--P. XV.
  • Metabolism of amino acids and amines. Part A-B pt. A-B, 1970-71.
    ScienceDirect
    pt. B,1971 ScienceDirect
  • "Arsenite contamination of drinking water is a major cause of chronic illness and mortality in many countries, but until recently little was known of the processes determining its movement and concentration. Bacterial oxidation of arsenite was first described in 1918 and thought to be a means of detoxification. It was not until 2000 that the first autotrophic arsenite-oxidising bacterium was isolated and shown to gain energy from arsenite oxidation. Since then a wide range of such bacteria has been isolated and the literature on the topic has grown rapidly. This book reviews the new understanding of the diversity and abundance of such organisms, their role in arsenic cycling in the environment and their possible relations with arsenic-dependent diseases in humans"-- Provided by publisher.
  • Introduction / Seetharaman Vaidyanathan, George G. Harrigan and Royston Goodacre -- Towards integrative functional genomics using yeast as a reference model / Juan I. Castrillo and Stephen G. Oliver -- Metabolomics for the assessment of functional diversity and quality traits in plants / Robert D. Hall ... [et al.] -- Metabolomics: a new approach towards identifying biomarkers and therapeutic targets in cns disorders / Rima Kaddurah-Daouk ... [et al.] -- Compaative metabolome profiling using two dimensional thin layer chromatography (2DTLC) / Thomas Ferenci and Ram Maharjan -- Capillary electrophoresis and its application in metabolome analysis / Li Jia and Shigeru Terabe -- Metabolic networks / Eivind Almaas, Zoltán N. Oltvai and Albert-László Barabási -- Metabolic networks from a systems perspective / Wolfran Weckwerth, Ralf Steuer -- Parallel metabolite and trascript profiling / Alisdair R. Fernie, Ewa Urbanczyk-Wochniak and Lothar Willmitzer -- Fluxome profiling in microbes / Nicola Zamboni and Uwe Sauer -- Targeted drug design and metabolic pathway flux / László G. Boros and Wai-Nang Paul Lee -- Metabonomics in the pharmaceutical industry / Eva M. Lenz, Rebecca Williams and Ian D. Wilson -- How lipidomic approaches will benefit the pharmaceutical industry / Alvin Berger -- Metabolites and fungal virulence / Edward M. Driggers and Axel A. Brakhage. Metabolite profiling with GC-MS and LC-MS / Ralf Looser, Arno J. Krotzky, Richard N. Trethewey -- The application of electrochemistry to metabolic profiling / David F. Meyer, Paul H. Gamache and Ian N. Acworth -- Differential metabolic profiling for biomarker discovery / Haihong Zhou, Aaron B. Kantor and Christopher H. Becker -- NMR-based metabonomics in toxicology research / Laura K. Schnackenberg, Richard D. Beger, and Yvonne P. Dragan -- Methodological issues and experimental design considerations in metabolic profile-based classifications / Bruce S. Kristal ... [et al.] -- Modelling of fungal metabolism / Helga David and Jens Nielsen -- Detailed kinetic models using metabolomics data sets / Jacky L. Snoep, Johann M. Rohwer --
  • Metabolomics methods and protocols 2006
    Springer Protocols
    Metabolite profiling in blood plasma / Oliver Fiehn and Tobias Kind -- Nonsupervised construction and application of mass spectral and retention time index libraries from time-of-flight GC/MS metabolite profiles / Alexander Erban ... [et al.] -- Metabolomic profiling of natural volatiles: head space trapping-GC/MS / Yury M. Tikunov, Francel W. A. Verstappen, and Robert D. Hall -- Integrative profiling of metabolites and proteins: improving pattern recognition and biomarker selection for systems-level approaches / Katja Morgenthal ... [et al.] -- Integrating profiling data: using linear correlation to reveal coregulation of transcript and metabolites / Ewa Urbanczyk-Wochniak, Lothar Willmitzer, and Alisdair R. Fernie -- Visualization and analysis of molecular data / Matthias Scholz and Joachim Selbig -- A gentle guide to the analysis of metabolomic data / Ralf Steuer ... [et al.] -- CE-MS for metabolomics / Tomoyoshi Soga -- Application of LC/MS analysis in metabolomics: reversed-phase monolithic capillary chromatography and hydrophilic chromatography coupled to electrospray ionization mass spectrometry / Vladimir V. Tolstikov, Oliver Fiehn, and Nobuo Tanaka -- HPLC-separations coupled with coulometric-electrode array detectors: a unique approach to metabolomics / Bruce S. Kristal ... [et al.] -- Determination of metabolic flux ratios from 13C-experiments and GC/MS data: protocol and principles / Annik Nanchen, Tobias Fuhrer, and Uwe Sauer -- Understanding the roadmap of metabolism by pathway analysis / Stefan Schuster, Axel von Kamp, and Mikhail Pachkov -- Revealing the metabolome of animal tissues using 1H NMR spectroscopy / Mark R. Viant -- NMR metabonomics: methods for drug discovery and development / Karl-Heinz Ott and Nelly Aranibar.
  • What Is Metadata? -- Data Types in the Medical Record -- Metadata and the Use of XML -- Representing Structured Clinical Data -- Building the User Interface for Structured Clinical Data Capture -- Medical Decision Support Systems: General Considerations -- Challenges in Electronic Decision Support Implementation -- Infrastructure for Complex Clinical Decision Support: Rule Engines -- Decision Support Infrastructure: Workflows and Service-Oriented Architectures -- Complex Decision Support in Practice -- Extending the Entity-Attribute-Value Model -- Descriptive Metadata: An Introduction to Terminologies -- Descriptive Metadata: Implementing Large-Scale Biomedical Ontologies -- Clinical Study Data Management Systems -- Data Retrieval for Heterogeneous Data Models -- Metadata for Data Warehousing -- Biomedical Metadata Standards.
  • Metagenomics methods and protocols 2010
    Springer Protocols
    Molecular Methods to Study Complex Microbial Communities / José M. Vieites, María-Eugenia Guazzaroni, Ana Beloqui, Peter N. Golyshin, and Manuel Ferrer -- Construction of Small-Insert and Large-Insert Metagenomic Libraries / Carola Simon and Rolf Daniel -- Construction and Screening of Marine Metagenomic Libraries / Nancy Weiland, Carolin Löscher, Rebekka Metzger, and Ruth Schmitz -- Metagenomic Analysis of Isotopically Enriched DNA / Yin Chen, Josh D. Neufeld, Marc G. Dumont, Michael W. Friedrich, and J. Colin Murrell -- Wide Host-Range Cloning for Functional Metagenomics / Margaret Wexler and Andrew W.B. Johnston -- Cloning and Expression Vectors for a Gram-Positive Host, Streptomyces lividans / Kristof Vrancken, Lieve Van Mellaert, and Jozef Anné -- Heterologous Gene Expression in the Hyperthermophilic Archaeon Sulfolobus solfataricus / Angel Angelov and Wolfgang Liebl -- Novel Tools for the Functional Expression of Metagenomic DNA / Sonja Christina Troeschel, Thomas Drepper, Christian Leggewie, Wolfgang R. Streit, and Karl-Erich Jaeger -- Screening of Functional Promoter from Metagenomic DNA for Practical Use in Expression Systems / So-Youn Park and Geun-Joong Kim -- Substrate-Induced Gene Expression Screening: A Method for High-Throughput Screening of Metagenome Libraries / Taku Uchiyama and Kentaro Miyazaki -- Screens for Active and Stereoselective Hydrolytic Enzymes / Dominique Böttcher, Marlen Schmidt, and Uwe T. Bornscheuer. Screening for Cellulase-Encoding Clones in Metagenomic Libraries / Nele Ilmberger and Wolfgang R. Streit -- Screening Metagenomic Libraries for Laccase Activities / Manuel Ferrer, Ana Beloqui, and Peter N. Golyshin -- Screening for N-AHSL-Based-Signaling Interfering Enzymes / Phil M. Oger and Stéphane Uroz -- Identification of Molecular Markers to Follow Up the Bioremediation of Sites Contaminated with Chlorinated Compounds / Massimo Marzorati, Annalisa Balloi, Francesca De Ferra, and Daniele Daffonchio -- Methods for the Isolation of Genes Encoding Novel PHB Cycle Enzymes from Complex Microbial Communities / Ricardo F. Nordeste, Maria A. Trainer, and Trevor C. Charles -- Metagenomic Approaches to Identify and Isolate Bioactive Natural Products from Microbiota of Marine Sponges / Cristian Gurgui and Jörn Piel -- Screening for Novel Antibiotic Resistance Genes / Mindy G. Brown, Elizabeth H. Mitchell, and David L. Balkwill -- Novel Metal Resistance Genes from Microorganisms: A Functional Metagenomic Approach / José E. González-Pastor and Salvador Mirete -- Retrieval of Full-Length Functional Genes Using Subtractive Hybridization Magnetic Bead Capture / Tracy Meiring, Inonge Mulako, Marla I. Tuffin, Quinton Meyer, and Donald A. Cowan -- Detection and Isolation of Selected Genes of Interest from Metagenomic Libraries by a DNA Microarray Approach / Gopal P. Pathak and Wolfgang Gärtner -- Application of DNA Microarray for Screening Metagenome Library Clones / Soo-Je Park, Jong-Chan Chae, and Sung-Keun Rhee -- MetaGenomeThreader: A Software Tool for Predicting Genes in DNA-Sequences of Metagenome Projects / David J. Schmitz-Hübsch and Stefan Kurtz.
  • 1.The human genome, microbiomes, and disease -- 2. Host genotype and the effect on microbial communities -- 3. The human microbiome and host-pathogen interactions -- 4. The human virome -- 5. Selection and sequencing of strains as references for human microbiome studies -- 6. The human vaginal microbiome -- 7. The human lung microbiome -- 8. The human skin microbiome in health and skin diseases -- 9. The human oral microbiome -- 10. Retraction: the human and his microbiome risk factors for infections -- 11. Retraction: infectogenomics: aspect of host responses to microbes in digestive tract -- 12. Autoimmune disease and human metagenome -- 13. Metagenomic applications and the potential for understanding chronic liver disease -- 14. Symbiotic gut microbiota and the modulation of human metabolic phenotypes -- 15. MetaHIT: the European Union project on metagenomics of the human intestinal tract -- 16. Implications of human microbiome research for the developing world -- Index.
  • Acid mine drainage biofilm -- Waseca County farm soil -- Whale fall community -- Methane-oxidizing archaea -- Human fecal virus -- Sargasso Sea marine microbial metagenome -- Human distal gut microbiome -- Enhanced biological phosphorus removal (EBPR) sludge community -- Mouse gut microbiota metagenome.
  • Metal ion in stroke 2012
    Springer
    This book illustrates remarkable roles of metal ions in the neuropathophysiology of stroke, which is a major cause of death and disability worldwide. Metal ions have unique chemical properties that allow them to play diverse roles in the brain. They regulate excitability and function as co-factors in cellular and genetic signaling pathways and therefore, have important roles ranging from essential to toxic. For the first time, the dyshomeostasis and pathophysiological actions of these metals in stroke are discussed systematically in thirty-six chapters in one volume. Highlighted metal ions include:Aluminum (Al)Arsenic (As)Cadmium (Cd)Calcium (Ca)Copper (Cu)Iron (Fe)Magnesium (Mg)Manganese (Mn)Mercury (Hg)Nickel (Ni)Potassium (K)Selenium (Se)Sodium (Na)Zinc (Zn).
  • Metal ions in the brain are a necessity as well as a poison. The presence of metal ions in the active sites of biological catalysts or metalloproteins and in the biological functioning of nucleic acids is very well documented and they are required for brain activity. On the other hand, metals are very effective in generating oxidative stress. This effect does not only play a role in immunology but also is the root of practically all neurodegenerative disorders by inducing disease via the death of neurons. Managing metal ions in the brain could therefore be an important strategy in the search for therapeutic agents used in the treatment of neurodegenerative diseases. This new title gives an overview to key topics in the area of metal ions in the brain. It focuses on the role of metal ions in neurological systems by describing their advantageous functions as well as their poisonous features. It is therefore of interest for scientists in biochemistry and biophysics, physiology, toxicology as well as for physicians focused on this topic.
  • 1. Physical and chemical properties of nano-sized metal particles / C.N.R. Rao, G.U. Kulkarni, and P.J. Thomas -- 2. Metal-containing polymers : cryochemical synthesis, structure, and physicochemical properties / L.I. Trakhtenberg and G.N. Gerasimov -- 3. Controlled pyrolysis of metal-containing precursors as a way for synthesis of metallopolymer nanocomposites / A.D. Pomogailo, A.S. Rozenberg, and G.I. Dzhardimalieva -- 4. Nanostructured polymeric nanoreactors for metal nanoparticle formation / L.M. Bronstein -- 5. Metal-polymer nanocomposite synthesis : novel ex situ and in situ approaches / G. Carotenuto ... [et al.] -- 6. Plamon absorption of embedded nanoparticles / A. Heilmann -- 7. Magnetooptics of granular materials and new optical methods of magnetic nanoparticles and nanostructures imaging / V.I. Belotelov, P. Perlo, and A.K. Zvezdin -- 8. Optical extinction of metal nanoparticles synthesized in polymer by ion implantation / A.L. Stepanov -- 9. Optically anisotropic metal-polymer nanocomposites / W. Caseri.
  • Chapter 1. ₃Li Lithium Metallotherapeutics / Robin S.B. Williams and Adrian J. Harwood, p. 1-17 -- Chapter 2. ₅B Boron Compounds as Therapeutic Drugs / Geeta Rana, Kamesh Vyakaranam, John A. Maguire and Narayan S. Hosmane, p. 19-49 -- Chapter 3. ₁₂Mg The Role of Magnesium As a Metallotherapeutic Drug / Pietro Delva, p. 51-64 -- Chapter 4. ₁₃Al Aluminum Metallotherapeutics / Thanos Salifoglou, p. 65-82 -- Chapter 5. ₁₄Si Biological Activity of Organosilicon Compounds / Edmunds Lukevics and Luba Ignatovich, p. 83-107 -- Chapter 6. ₂₀Ca The Role of Calcium As a Metallotherapeutic Drug / Mario Barbagallo and Ligia J. Dominguez, p. 109-124 -- Chapter 7. ₂₂Ti Anti-Tumor Titanium Drugs / Erich Dubler, p. 125-142 -- Chapter 8. ₂₃V Insulin-Mimetic Vanadium-Containing Compounds / Tamás Kiss and Tamás Jakusch, p. 143-158 -- Chapter 9. ₂₅Mn Manganese Metallotherapeutics / Jeanne H. Freeland-Graves, Tanushree Bose and Abbass Karbassian, p. 159-178 -- Chapter 10. ₂₆Fe The Use of Iron-Based Drugs in Medicine / Xiang Wu and Mei Lin Go, p. 179-200 -- Chapter 11. ₂₇Co Cobalt Complexes As Potential Pharmaceutical Agents / Hui Chao and Liang-Nian Ji, p. 201-218 -- Chapter 12. ₂₉Cu Chemotherapeutic Copper Compounds / Francisco González-Vílchez and Rosario Vilaplana, p. 219-236 -- Chapter 13. ₃₀Zn The Role of Zinc As a Metallotherapeutic Agent / Jane V. Higdon and Emily Ho, p. 237-257 -- Chapter 14. ₃₁Ga Therapeutic Gallium Compounds / Lawrence R. Bernstein, p. 259-277 -- Chapter 15. ₃₂Ge Biological Activity of Organogermanium Compounds / Edmunds Lukevics and Luba Ignatovich, p. 279-295 -- Chapter 16. ₃₃As Metallotherapeutic Arsenic Compounds / Paul C. Ho, p. 297-311 -- Chapter 17. ₃₄Se The Use of Selenium-Based Drugs in Medicine / Michael Carland and Tahli Fenner, p. 313-332 -- Chapter 18. ₄₃Tc Technetium in Medicine / Oyebola O. Sogbein and John F. Valliant, p. 333-358 -- Chapter 19. ₄₄Ru Perspectives of Ruthenium Complexes in Cancer Therapy / Olivier Lentzen, Cécile Moucheron and Andrée Kirsch-De Mesmaeker, p. 359-378 -- Chapter 20. ₄₅Rh Rhodium in Medicine / Florian P. Pruchnik, p. 379-397 -- Chapter 21. ₄₆Pd The Use of Palladium Complexes in Medicine / Achilleas Garoufis, Sotiris K. Hadjikakou and Nick Hadjiliadis, p. 399-419 -- Chapter 22. ₅₀Sn Tin Compounds and Their Therapeutic Potential / Marcel Gielen and Edward R.T. Tiekink, p. 421-439 -- Chapter 23. ₅₁Sb Antimony in Medicine / Siucheong Yan, Lan Jin and Hongzhe Sun, p. 441-461 -- Chapter 24. ₇₅Re Therapeutic Rhenium Radiopharmaceuticals / Jonathan R. Dilworth and Paul S. Donnelly, p. 463-487 -- Chapter 25. ₇₈Pt Platinum-Based Drugs / Viktor Brabec and Jana Kasparkova, p. 489-506 -- Chapter 26. ₇₉Au Gold-Based Metallotherapeutics: Use and Potential / Soo Yei Ho and Edward R.T. Tiekink, p. 507-527 -- Chapter 27. ₈₃Bi Bismuth-Based Pharmaceuticals / Neil Burford and Melanie D. Eelman, p. 529-540 -- Chapter 28. Paramagnetic Metal Complexes As Contrast Agents for Magnetic Resonance Imaging / Silvio Aime, Alessandro Barge, Eliana Gianolio, Simonetta Geninatti Crich, Walter Dastrú and Fulvio Uggeri, p. 541-560.
  • Print Material
    "Georges Vigarello maps the evolution of Western ideas about fat and fat people from the Middle Ages to the present, paying particular attention to the role of science, fashion, fitness crazes, and public health campaigns in shaping these views. Although hefty bodies were once a sign of power, today those who struggle to lose weight are considered poor in character and weak in mind. Vigarello traces the eventual equation of fatness with infirmity and the way we have come to define ourselves and others in terms of body type. Vigarello begins with the medieval artists and intellectuals who treated heavy bodies as symbols of force and prosperity. He then follows the shift during the Renaissance and early modern period to courtly, medical, and religious codes that increasingly favored moderation and discouraged excess. Scientific advances in the eighteenth century also brought greater knowledge of food and the body's processes, recasting fatness as the "relaxed" antithesis of health. The body-as-mechanism metaphor intensified in the early nineteenth century, with the chemistry revolution and heightened attention to food-as-fuel, which turned the body into a kind of furnace or engine. During this period, social attitudes towards fat became conflicted, with the bourgeois male belly operating as a sign of prestige but also as a symbol of greed and exploitation, while the overweight female was admired only if she was working class. Vigarello concludes with the fitness and body-conscious movements of the twentieth century and the proliferation of personal confessions about obesity, which tied fat more closely to notions of personality, politics, taste, and class."--Book Jacket.
  • When analyzing the results of diagnostic imaging studies, the radiologist traditionally makes reference to particular features representative of normality or pathology. Most of these features are associated with images of the world around us. This pictorial issue contains nearly 400 illustrations and descriptions of more than 100 classic radiological signs of chest and abdominal diseases that are not named after authors but based on metaphors derived from contemplation of our environment. By correlating the results of computed tomography with these vivid descriptive images, readers will be able to memorize typical and often pathognomonic patterns of disease more quickly and more easily. This book will be of value for both radiology residents and more experienced radiologists.
  • 1. The metastatic process: an overview -- 2. Physiopathology of colorectal metastasis -- 3. The genetics of colorectal cancer -- 4. Epigenetics of colorectal cancer -- 5. Cancer-initiating cells in colorectal cancer -- 6. Epithelial-mesenchymal transition in colorectal cancer -- 7. Cell adhesion molecules in colon cancer metastasis -- 8. Epithelial cell signalling in colorectal cancer metastasis -- 9. Angiogenesis and lymphangiogenesis in colon cancer metastasis -- 10. Role of the host inflammaory response in colon carcinoma initiation, progression, and liver metastasis -- 11. Molecular prognostic markers in colon cancer -- 12. The sentinel lymph node and staging of colorectal cancer -- 13. Treatment of colorectal cancer -- 14. Diagnosis and treatment of rectal cancer -- 15. Future directions -- Index.
  • v. 2 Springer Protocols
    v. 1. Analysis of cells and tissues -- v. 2. Analysis of cell behavior in vitro and in vivo.
  • Clinical, epidemiologic, and laboratory aspects of methicillin-resistant Staphylococcus aureus (MRSA) infections / Elizabeth Palavecino -- MRSA case studies / Kurt D. Reed, Mary E. Stemper, and Sanjay K. Shukla -- MIC analysis and susceptibility testing of MRSA / German Bou -- ITS-PCR identification of MRSA / Shin-ichi Fujita -- Pulsed-field gel electrophoresis of methicillin-resistant Staphylococcus aureus / Kurt D. Reed, Mary E. Stemper, and Sanjay K. Shukla -- Multilocus sequence typing (MLST) of Staphylococcus aureus / Nicholas A. Saunders and Anne Holmes -- Staphylococcal cassette chromosome mec (SCCmec) analysis of MRSA / Teruyo Ito, Kyoko Kuwahara, and Keiichi Hiramatsu -- Targeted gene disruption for the analysis of virulence of Staphylococcus aureus / J. Ross Fitzgerald -- Molecular analysis of staphylococcal superantigens / Patrick M. Schlievert and Laura C. Case -- Investigation of biofilm formation in clinical isolates of Staphylococcus aureus / James E. Cassat, Chia Y. Lee, and Mark S. Smeltzer -- Comparative analysis of staphylococcal adhesion and internalization by epithelial cells / Xudong Liang and Yinduo Ji -- Comparative analysis of MRSA / Fumihiko Takeuchi, Tadashi Baba, and Keiichi Hiramatsu -- Genomic analysis of gene expression of Staphylococcus aureus / Chuanxin Yu ... [et al.] -- Proteomic approach to investigate methicillin-resistant Staphylococcus aureus / Patrice Francois ... [et al.] -- Environmental surveillance for methicillin-resistant Staphylococcus aureus / J. Scott Weese -- The control and prevention of MRSA infections / Liangsu Wang and John F. Barrett -- Treatment of infections due to resistant Staphylococcus aureus / Gregory M. Anstead, Gabriel Quinones-Nazario, and James S. Lewis II.
  • "This IOM committee was formed at the request of the Bill & Melinda Gates Foundation and charged with addressing methodological challenges in late-stage nonvaccine biomedical HIV prevention trials with a specific focus on microbicide and pre-exposure prophylaxis trials."
  • Print Material
  • Print Material
  • Chronic recording during learning / Aaron J. Sandler -- Defining global brain states using multielectrode field potential recordings / Shih-Chieh Lin and Damien Gervasoni -- Multielectrode recording in behaving monkeys / R.E. Crist and M.A. Lebedev -- Neural ensemble recordings from central gustatory-reward pathways in awake and behaving animals / Albino J. Oliveira-Maia, Sidney A. Simon, and Miguel A.L. Nicolelis -- Building brain-machine interfaces to restore neurological functions / Mikhail A. Lebedev, Roy E. Crist, and Miguel A.L. Nicolelis -- Conceptual and technical approaches to human neural ensemble recordings / Dennis A. Turner, Parag G. Patil, and Miguel A.L. Nicolelis. State-of-the-art microwire array design for chronic neural recordings in behaving animals / Gary Lehew and Miguel A.L. Nicolelis -- Surgical techniques for chronic implantation of microwire arrays in rodents and primates / Laura M.O. Oliveira and Dragan Dimitrov -- Technology for multielectrode microstimulation of brain tissue / Timothy Hanson, Nathan Fitzsimmons, and Joseph E. O'Doherty -- Strategies for neural ensemble data analysis for brain-machine interface (BMI) applications / Miriam Zacksenhouse and Simona Nemets -- Chronic recordings in transgenic mice / Kafui Dzirasa -- Multielectrode recordings in the somatosensory system / Michael Wiest, Erik Thomson, and Jim Meloy --
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  • "Effectiveness and Comparative Effectiveness Reviews, systematic reviews of existing research on the effectiveness, comparative effectiveness, and comparative harms of different medical tests, are intended to provide relevant evidence to inform real-world health care decisions for patients, providers, and policymakers. In an effort to improve the transparency, consistency, and scientific rigor of the work of the Effective Health Care (EHC) Program, the Agency for Healthcare Research and Quality (AHRQ), the Scientific Resource Center, and the Evidence-based Practice Centers (EPCs), have developed this Methods Guide for Medical Test Reviews (also referred to as the Medical Test Methods Guide). We intend it to serve as a resource for the EPCs as well as for other investigators interested in conducting systematic reviews on medical tests. We hope it will be a practical guide both for those who prepare the systematic reviews and those who use them in clinical practice, research development, and in making policy decisions."
  • Methods in biobanking 2011
    Springer Protocols
    Genetic research and biobanks / D. Chalmers -- The need to downregulate: A minimal ethical framework for biobank research / M.G. Hansson -- Nordic biological specimen bank cohorts as basis for studies of cancer causes and control: Quality control tools for study cohorts with more than two million sample donors and 130,000 prospective cancers / E. Pukkala -- Biobanks collected for routine healthcare purposes: Build-up and use for epidemiologic research / J. Dillner and K. Andersson -- Biobanks and registers in epidemiologic research on cancer / E. Pukkala -- Study designs for biobank-based epidemiologic research on chronic diseases / E. Laara -- The European prospective investigation into cancer and nutrition biobank / P. Hainaut ... [et al.] -- The aids and cancer specimen resource / L.W. Ayers ... [et al.] -- Specific advantages of twin registries and biobanks / J. Kaprio -- The Swedish multi-generation register / A. Ekbom -- Multigenerational information: The example of the Icelandic genealogy database / H. Tulinius -- Creation of a new prospective research biobank: The example of HUNT3 / K. Hveem -- Best practices for establishing a biobank / G. Hallmans and J.B. Vaught -- Extraction, quantitation, and evaluation of function DNA from various sample types / M. Ivarsson and J. Carlson -- Cervical cytology biobanks as a resource for molecular epidemiology / M. Arbyn ... [et al.] -- Biobanking of fresh frozen tissue from clinical surgical specimens: Transport logistics, sample selection, and histologic characterization / J. Botling and P. Micke -- Protein extraction from solid tissue / C. Ericsson and M. Nister -- Collection and preservation of frozen microorganisms / R. Tedeschi and P. De Paoli -- Handling of solid brain tumor tissue for protein analysis / C. Ericsson and M. Nister -- Blood plasma handling for protein analysis / C. Ericsson and M. Nister -- Biobank informatics: Connecting genotypes and phenotypes / J.E. Litton -- A practical guide to constructing and using tissue microarrays / I. Chandler, R. Houlston and G. Landberg -- Breast cancer genomics based on biobanks / A. Forsti and K. Hemminki -- Monitoring, alarm, and data visualization service on sample preparing and sample storing devices in biobanks / H. Hauksdottir, K. Jonsdottir and A. Thorarinsson -- Fresh frozen tissue: RNA extraction and quality control / J. Botling and P. Micke.
  • Seeking to cross the bridge among overview, theory, and practice, this book incorporates both methodological approaches and their potential application in the domains associated with biomedical informatics.The multi-contributor book is useful for (1) those coming from a domain seeking biomedical informatics approaches for addressing specific needs; and, (2) current biomedical informaticians seeking a foundational background for methods that might be utilized in practical scenarios germane to their ongoing research.A unique characteristic of the text is its balance between foundational coverage of core topics in biomedical informatics with practical "in-the-trenches" scenarios. Contributors represent leading experts from the biomedical informatics field: individuals who have demonstrated effective use of methodology in real-world, high-quality data applications. Contains appendices that function as primers on: (1) Unix; (2) Ruby; (3) Databases; and (4) Web Services.
  • Methods in biotechnology v. 1-, 1997-
    Springer Protocols
  • Methods in cilia & flagella 2015
    ScienceDirect
    Imaging centrosomes and cilia in the mouse kidney / Masato Hoshi, Jinzhi Wang, Sanjay Jain, Moe R. Mahjoub -- Ependymal cell differentiation, from monociliated to multiciliated cells / Nathalie Delgehyr, Alice Meunier, Marion Faucourt, Montserrat Bosch Grau, Laetitia Strehl, Carsten Janke, Nathalie Spassky -- Observing planar cell polarity in multiciliated mouse airway epithelial cells / Eszter K. Vladar, Yin Loon Lee, Tim Stearns, Jeffrey D. Axelrod -- Imaging and analyzing primary cilia in cardiac cells / Nicolas Diguet, Jean-Francois Le Garrec, Tommaso Lucchesi, Sigolene M. Meilhac -- Cilia in photoreceptors / Linjing Li, Manisha Anand, Kollu Nageswara Rao, Hemant Khanna -- Analysis of primary cilia in the developing mouse brain / Judith T.M.L. Paridaen, Wieland B. Huttner, Michaela Wilsch-Brauninger -- In vivo investigation of cilia structure and function using Xenopus / Eric R. Brooks, John B. Wallingford -- A quantitative approach to study endothelial cilia bending stiffness during blood flow mechanodetection in-vivo / Francesco Boselli, Jacky G. Goetz, Gilles Charvin, Julien Vermot -- Quantitative description of fluid flows produced by left-right cilia in zebrafish / Craig Fox, M. Lisa Manning, Jeffrey D. Amack -- Efficient live fluorescence imaging of intraflagellar transport in mammalian primary cilia / Hiroaki Ishikawa, Wallace F. Marshall -- Analysis of soluble protein entry into primary cilia using semipermeabilized cells / David K. Breslow, Maxence V. Nachury -- Methods for imaging individual cilia in living echinoid embryos / Robert L. Morris, Hans W. Pope, Adam N. Sholi, Leah M. Williams, Chelsea R. Ettinger, Gwendolyn M. Beacham, Tatsushi Shintaku, Zachary D. Abbott, Elyse M. Doherty -- The planarian Schmidtea mediterranea as a model for studying motile cilia and multiciliated cells / Cyril Basquin, Anne-Marie Orfila, Juliette Azimzadeh -- Quantitative analysis of flagellar proteins in Drosophila sperm tails / Teresa Mendes Maia, Perrine Paul-Gilloteaux, Renata Basto -- Imaging cilia in Drosophila melanogaster / Jennifer Vieillard, Jean-Luc Duteyrat, Elisabeth Cortier, Benedicte Durand -- Studying G protein-coupled receptors: Immunoblotting, immunoprecipitation, phosphorylation, surface labeling, and cross-linking protocols / Kasturi Pal, Hemant Badgandi, Saikat Mukhopadhyay -- Image analysis of Caenorhabditis elegans ciliary transition zone structure, ultrastructure, molecular composition and function / Anna A. W. M. Sanders, Julie Kennedy, Oliver E. Blacque -- Genetic and genomic approaches to identify genes involved in flagellar assembly in Chlamydomonas reinhardtii / Huawen Lin, Susan K. Dutcher -- Axonemal motility in Chlamydomonas / Ken-ichi Wakabayashi, Ritsu Kamiya -- Posttranscriptional control over rapid development and ciliogenesis in marsilea / Stephen M. Wolniak, Thomas C. Boothby, Corine M. van der Weele -- Total internal reflection fluorescence microscopy of intraflagellar transport in tetrahymena thermophila / Yu-Yang Jiang, Karl Lechtreck, Jacek Gaertig -- Ciliary heterogeneity within a single cell : the paramecium model / Anne Aubusson-Fleury, Jean Cohen, Michel Lemullois -- Imaging intraflagellar transport in trypanosomes / Julien Santi-Rocca, Nicolas Chenouard, Cécile Fort, Thibault Lagache, Jean-Christophe Olivo-Marin, Philippe Bastin -- Scanning and three-dimensional electron microscopy methods for the study of trypanosoma brucei and leishmania mexicana flagella / Eva Gluenz, Richard John Wheeler, Louise Hughes, Sue Vaughan.
  • Print Material
    v. 1. Laboratory methods, pts. A-C -- v. 2. Clinical methods.
  • Methods in enzymology v. 1-, 1955-
    ScienceDirect
  • Print Material
    v. 1. Chemical determinations -- v. 2. Bioassay -- v. 3. & 4. Steroidal activity in experimental animals and man, Part A & B.
  • Methods in membrane lipids 2007
    Springer Protocols
  • 1. Techniques for cultivating methanogens / Ralph S. Wolfe -- 2. Genetic methods for methanosarcina species / Nicole Buan, Gargi Kulkarni, and William Metcalf -- 3. Genetic systems for hydrogenotrophic methanogens / Felipe Sarmiento B., John A. Leigh, and William B. Whitman -- 4. Molecular tools for investigating ANME community structure and function / Steven J. Hallam ... [et al.] -- 5. Studying gene regulation in methanogenic archaea / Michael Rother, Christian Sattler, and Tilmann Stock -- 6. Growth of methanogens under defined hydrogen conditions / John A. Leigh -- 7. Preparation of [Fe]-hydrogenase from methanogenic archaea / Seigo Shima, Michael Schick, and Haruka Tamura -- 8. Assay of methylotrophic methyltransferases from methanogenic archaea / Donald J. Ferguson, David G. Longstaff, and Joseph A. Krzycki -- 9. Methyl-coenzyme M reductase from methanothermobacter marburgensis / Evert C. Duin, Divya Prakash, and Charlene Brungess -- 10. Methods for analysis of acetyl-CoA synthase : applications to bacterial and archaeal systems / David A. Grahame -- 11. Acetate kinase and phosphotransacetylase / James G. Ferry -- 12. Sodium ion translocation and ATP synthesis in methanogens / Katharina Schlegel and Volker Müller -- 13. Proton translocation in methanogens / Cornelia Welte and Uwe Deppenmeier -- 14. Measuring isotope fractionation by autotrophic microorganisms and enzymes / Kathleen M. Scott, Gordon Fox, and Peter R. Girguis -- 15. 2-oxoacid metabolism in methanogenic CoM and CoB biosynthesis / David E. Graham -- 16. Biomethanation and its potential / Irini Angelidaki ... [et al.].
  • A comprehensive analysis of the effect of microarray data preprocessing methods on differentially expressed transcript selection -- Differentiation detection in microarray normalization -- Preprocessing and normalization for Affymetrix GeneChip expression microarrays -- Spatial detrending and normalization methods for two-channel DNA and protein microarray data -- A survey of cDNA microarray normalization and a comparison by k-NN classification -- Technical variation in modeling the joint expression of several genes -- Biological interpretation for microarray normalization selection -- Methodology of functional analysis for omics data normalization -- Exon array analysis for the detection of alternative splicing -- Normalization of array CGH data -- SNP array-based analysis for the detection of chromosomal aberrations and copy number variations.
  • The three-dimensional structure of proteins. -- Liquid chromatography of biomolecules. -- Mass spectrometry. -- X-ray structural analysis. -- Protein infrared spectroscopy. -- Electron microscopy. -- Scanning probe microscopy. -- Biophysical nanotechnology. -- Proteomics: high throughput protein functional analysis. -- Ion mobility spectrometry. -- Ø-value analysis. -- Evolutionary computer programming. -- Conclusions.
  • Methods in molecular biology (Humana Press) v. 1-, 1984-
    Springer Protocols
  • Methods in molecular medicine v. 1-, 1996-
    Springer Protocols
  • Methods in protein design 2013
    ScienceDirect
    Computational design of novel protein binders and experimental affinity maturation -- Mining tertiary structural motifs for assessment of designability -- Computational methods for controlling binding specificity -- Flexible backbone sampling methods to model and design protein alternative conformations -- Osprey: protein design with ensembles, flexibility, and provable algorithms -- Scientific benchmarks for guiding macromolecular energy function improvement -- Molecular dynamics simulations for the ranking, evaluation, and refinement of computationally designed proteins -- Multistate protein design using CLEVER and CLASSY -- Using analyses of amino acid coevolution to understand protein structure and function -- Evolution-based design of proteins -- Protein engineering and stabilization from sequence statistics: variation and covariation analysis -- Enzyme engineering by targeted libraries -- Generation of high-performance binding proteins for pepetide motifs by affinity clamping -- Engineering fibronectin-based binding proteins by yeast surface display -- Engineering and analysis of peptide-recognition domain specificities by phage display and deep sequencing -- Efficient sampling of SCHEMA chimera families to identify useful sequence elements -- Protein switch engineering by domain insertion -- Design of chimeric proteins by combination of subdomain-sized fragments -- [alpha]-helix mimicry with [alpha/beta]-peptides.
  • pt. B ScienceDirect
  • Phytoestrogens / B. Dave Oomah and Farah S. Hosseinian -- Analysis of fatty acids in functional foods with emphasis on [omega] 3 fatty acids and conjugated linoleic acid / Gary Dobson -- Analysis of flavonoids in functional foods and nutraceuticals / Laura Bravo and Raquel Mateos -- Exploitation of residues from vineyards, olive groves, and wine and oil production to obtain phenolic compounds of high-added value / María D. Luque de Castro, José M. Luque-Rodríguez, and Rafael Japón-Luján -- Anthocyanins / Gary Takeoka and Lan Dao -- Carotenoids and provitamin A in functional foods / María Isabel Mí́nguez-Mosquera, Dámaso Hornero-Méndez, and Antonio Pérez-Gálvez -- Chlorophylls / María Isabel Mí́nguez-Mosquera ... [et al.] -- Water-soluble vitamins / Míguel Ángel Fernández-Muiño, María Teresa Sancho-Ortiz, and Felicidad Valls-García -- Amino acid analysis / Larry R. Massom -- Carbohydrates and other electrochemically active compounds in functional foods / William R. LaCourse.
  • DSU Title III 2002-2012.
  • "Methods of Clinical Epidemiology" serves as a text on methods useful to clinical researchers. It provides a clear introduction to the common research methodology specific to clinical research for both students and researchers. This book sets out to fill the gap left by texts that concentrate on public health epidemiology and focuses on what is not covered well in such texts. The four sections cover methods that have not previously been brought together in one text and serves as a second level textbook of clinical epidemiology methodology. This book will be of use to postgraduate students in clinical epidemiology as well as clinical researchers at the start of their careers.
  • Methods of microarray data analysis v. 4-5, 2005-07.
    Springer
    v. 5 (2007) Springer
  • Annotation Mercury (Hg) is a global pollutant that knows no environmental boundaries. Even the most stringent control of anthropogenic Hg sources will not eliminate exposure given its ubiquitous presence. Exposure to Hg occurs primarily via the food chain due to MeHgs accumulation in fish. Latest US statistics indicate that 46 States have fish consumption advisories. In addition, Hg is a common pollutant in hazardous waste sites, with an estimated 3-4 million children living within one mile of at least one of the 1,300+ active hazardous waste sites in the US. The effects on intellectual function in children prenatally exposed to MeHg via maternal fish consumption have been the subject of two on-going major, prospective, longitudinal studies in the Seychelles and the Faroe Islands. It is important to recognize that the risk for MeHg exposure is not limited only to islanders with high fish consumption. This bookwill provide state-of-the-art information to the graduate student training in toxicology, risk assessors, researchers and medical providers at large. It is aimed to bring the reader up to date on contemporary issues associated with exposure to methylmercury, from its effects on stem cells and neurons to population studies.
  • Methylxanthines 2011
    Springer
    Notes on the History of Caffeine Use / Bertil B. Fredholm -- Distribution, Biosynthesis and Catabolism of Methylxanthines in Plants / Hiroshi Ashihara, Misako Kato and Alan Crozier -- Pharmacokinetics and Metabolism of Natural Methylxanthines in Animal and Man / Maurice J. Arnaud -- Inhibition of Cyclic Nucleotide Phosphodiesterases by Methylxanthines and Related Compounds / Sharron H. Francis, Konjeti R. Sekhar, Hengming Ke and Jackie D. Corbin -- Methylxanthines and Ryanodine Receptor Channels / Serge Guerreiro, Marc Marien and Patrick P. Michel -- Xanthines as Adenosine Receptor Antagonists / Christa E. Müller and Kenneth A. Jacobson -- Theobromine and the Pharmacology of Cocoa / Hendrik Jan Smit -- Propentofylline: Glial Modulation, Neuroprotection, and Alleviation of Chronic Pain / Sarah Sweitzer and Joyce De Leo -- Methylxanthines, Seizures, and Excitotoxicity / Detlev Boison -- Impacts of Methylxanthines and Adenosine Receptors on Neurodegeneration: Human and Experimental Studies / Jiang-Fan Chen and Yijuang Chern -- Methylxanthines and Pain / Jana Sawynok -- Methylxanthines and Sleep / Tarja Porkka-Heiskanen -- Methylxanthines and Reproduction / Alba Minelli and Ilaria Bellezza -- Methylxanthines During Pregnancy and Early Postnatal Life / Ulrika Ådén -- Methylxanthines and the Kidney / Hartmut Osswald and Jürgen Schnermann -- The Cardiovascular Effects of Methylxanthines / Niels P. Riksen, Paul Smits and Gerard A. Rongen -- Methylxanthines in Asthma / Stephen L. Tilley -- Methylxanthines and Inflammatory Cells / György Haskó and Bruce Cronstein -- Methylxanthines, Inflammation, and Cancer: Fundamental Mechanisms / Akio Ohta and Michail Sitkovsky -- Methylxanthines and Drug Dependence: A Focus on Interactions with Substances of Abuse / Micaela Morelli and Nicola Simola -- Methylxanthines and Human Health: Epidemiological and Experimental Evidence / Marie-Soleil Beaudoin and Terry E. Graham.
  • A new paradigm -- Clinical embryology of the abdomen -- Clinical anatomy of the abdomen -- Mechanisms of spread of disease in the abdomen and pelvis -- Intraperitoneal spread of infections and seeded metastases -- The extraperitoneal spaces: normal and pathologic anatomy -- The extraperitoneal pelvic compartments -- Patterns of spread of disease from the liver -- Patterns of spread of disease from the distal esophagus and stomach -- Patterns of spread of disease from the pancreas -- Patterns of spread of disease from the small intestine -- Patterns of spread of disease from the large intestine -- Patterns of spread of renal, upper urothelial, and adrenal pathology -- Patterns of spread of disease of the pelvis and male urogenital organs -- Patterns of spread of gynecologic disease -- Patterns of extraabdominal and extrapelvic spread -- Internal abdominal hernias.
  • Corticosteroids and related drugs -- Prostaglandins -- Sex hormones and related drugs -- Iodine and drugs that affect thyroid function -- Insulins and other hypoglycemic drugs -- Other hormones and related drugs -- Lipid-regulating drugs -- Endocrine and metabolic adverse effects of non-hormonal and non-metabolic drugs.
  • Elsevier now offers a series of derivative works based on the acclaimed Meyler's Side Effect of Drugs, 15th Edition. These individual volumes are grouped by specialty to benefit the practicing biomedical researcher and/or clinician. Opioids and analgesics are members of a diverse group of drugs used to relieve pain. They are frequently used in combination with prescription and nonprescription pain relievers, and misuse is prevalent. Pain medicine specialists and most physicians or surgeons will find this volume useful in prescribing the appropriate drugs for pain therapy and for preventing mi.
  • Antibacerial Drugs -- Antiviral Drugs, Including Immunoglobulins and Interferons -- Antifungal Drugs -- Antiprotozoal and Antihelminthic Drugs -- Vaccines -- Disinfectants and Antiseptics.
  • Elsevier now offers a series of derivative works based on the acclaimed Meylers Side Effect of Drugs, 15th Edition. These individual volumes are grouped by specialty to benefit the practicing physician or health care clinician. Each year, heart disease kills more people than cancer. Patients are treated by a variety of specialists and primary care practitioners, depending on the organ system involved. This volume enables practitioners to assess the adverse effects of the complete range of drugs used in cardiovascular medicine, including antihypertensive drugs, and drugs used in the treatment.
  • GENERAL ANESTHETICS -- LOCAL ANESTHETICS -- NEUROMUSCULAR BLOCKING DRUGS AND MUSCLE RELAXANTS.
  • Drugs Used in Cancer Chemotherpy -- Corticosteroids and Prostaglandins -- Cytokines and Cytokine Modulators Interferons -- Monoclonal Antibodies -- Immune Modulators.
  • Elsevier now offers a series of derivative works based on the acclaimed Meyler's Side Effect of Drugs, 15th Edition. These individual volumes are grouped by specialty to benefit the practicing physician and/or clinician. Many of the drugs currently available to physicians have a long history of use as herbal remedies, including opium, aspirin, digitalis, and quinine. This volume will be a reference to health professionals and homeopathic practitioners in understanding the effects of herbal drugs. Surpasses the Physician's Desk Reference © by including clinical case studies and independent exper.
  • Antidepressants -- Neuroleptic Drugs -- Hypnosedatives -- Drugs of Abuse -- Drugs use in Alzheimer's Disease -- Psychological and Psychiatric Adverse Effects of Non-Psychoactive Drugs.
  • Preparing for the cardiology board examination is an intensely stressful period and traditionally relies on the participant searching through their own references, whether that be the large textbooks, small handbooks and their own notes. Good books are generally too long and time-consuming, while shorter books are either insubstantial in content or rely too much on the views of one author. The key elements for a successful reference for those taking their boards are a balanced proportion of essential content alongside rare but frequently tested topics, the wisdom of experts in the field, a practical questions session at the end of every topic and additional visuals not possible on the two-dimensional page. In the MGH Cardiology Board Review, the Editors have compiled the expertise of over 72 experienced authors from the Mass General in a succinct volume, applying methods thoroughly tested in the Board Review Conference. In addition, two very important sections are included on ECGs and images, contents of which are derived from the board examination answer keys, the very ones that readers are expected to know. Plans on how to best approach the board examination preparation and what additional resources to go to are provided. In short, this book has all the strengths to ensure your success on the boards exam.
  • 1. Anesthesia equipment and patient safety / Arna Banerjee, L. Jane Easdown, and Matthew B. Weinger -- 2. Medical gases: properties, supply, and removal / Jesse M. Ehrenfeld and Michael Oleyar -- 3. Anesthesia machine: a practical overview / Jeffrey M. Feldmann -- 4. Principles and practices of closed circuit anesthesia / Robert S. Holzman and Rebecca Lintner -- 5. Manual and mechanical ventilators / Demet Suleymanci, Robert M. Kacmarek, and Yandong Jiang -- 6. Supraglottic airway devices / Jordan L. Newmark and Warren S. Sandberg -- 7. Intubation equipment / Zhongcong Xie, Ali Diba, and Zhipeng Xu -- 8. Endotracheal airway devices / Young K. Ahn and Warren S. Sandberg -- 9. Noninvasive physiological monitors / Jordan L. Newmark and Warren S. Sandberg -- 10. Invasive hemodynamic monitoring / Beverly J. Newhouse and Rafael Montecino -- 11. Transesophageal echocardiography / Jacob Kaczmarski and Sugantha Sundar -- 12. Depth of anesthesia monitoring: principles and applications / Roy Esaki and George Mashour -- 13. Alarms in clinical anesthesia / F. Jacob Seagull and Richard P. Dutton -- 14. Equipment for regional anesthesia and acute pain management / Reuben Slater and Lisa Warren -- 15. Ultrasound for regional anesthesia and vascular access / Lisa Warren and Reuben Slater -- 16. Intravenous therapy, fluid delivery systems for resuscitation, and cell salvage devices / Vanessa G. Henke and Warren S. Sandberg -- 17. Drug infusion pumps in anesthesia, critical care, and pain management / Nathaniel Sims ... [et al.] -- 18. Devices for cardiac support / Michael G. Fitzsimons, Stephanie Ennis, and Thomas MacGillivray -- 19. Patient warming devices / Jennifer A. Chatburn and Warren S. Sandberg -- 20. Point-of-care testing in the operating room / Marianna P. Crowley -- 21. Anesthesia information management systems / Sachin Kheterpal -- 22. Pediatric considerations / Rebecca N. Lintner and Robert S. Holzman -- 23. Anesthesia equipment outside of the operating room / Sergio D. Bergese, Erika G. Puente, and Gilat Zisman -- 24. Provision of anesthesia in difficult situations and the developing world / Deborah J. Harris ... [et al.] -- 25. Prevention of infection: disinfection and sterilization of equipment / Arnold J. Berry -- 26. Legal and regulatory issues / Eric T. Pierce -- 27. Physical principles / Paul D. Davis -- 28. Basic physics of electricity / Paul D. Davis -- 29. Operating room electrical, fire, laser, and radiation safety / Anuja K. Antony, Chunbai Zhang, and William G. Austen -- 30. Neuroanesthesia equipment in the intraoperative setting / Sergio D. Bergese, Gilat Zisman, and Erika G. Puente.
  • Overview of MHC Class I Antigens -- HLA Class I Expression in Human Cancer -- MHC Class I Expression in Experimental Mouse Models of Cancer: Immunotherapy of Tumors with Different MHC-I Expression Patterns -- Potential Therapeutic Approaches for Increasing Tumor Immunogenicity by Upregulation of Tumor HLA Class I Expression -- Conclusions.
  • MHC protocols 2002
    Springer Protocols
  • The mhGAP-IG has been developed through an intensive process of evidence review. A WHO Guideline Development Group of international experts conducted systematic reviews to develop evidence-based recommendations. The recommendations were then converted into clearly presented stepwise interventions and then circulated among a wider range of reviewers across the world to include all the diverse contributions. The mhGAP-IG is based on the mhGAP Guidelines on interventions for mental, neurological and substance use disorders (http:// www.who.int/mental_health/mhgap/evidence/en/). Both documents will be reviewed and updated in 5 years. Any revision and update before that will be made to the online version of the document.--(excerpt, p. 1).
  • MICAD
    NCBI Bookshelf
    This searchable database is a collection of in vivo molecular imaging agents developed for positron emission tomography (PET), single photon emission computed tomography (SPECT), magnetic resonance imaging (MRI), ultrasound (US), computed tomography (CT), and optical imaging. MICAD, a key component of the "Molecular Libraries and Imaging" program of the NIH Roadmap, is being developed by NCBI, the National Center for Biotechnology Information".
  • Micellar catalysis 2007
    CRCnetBASE
  • Print Material
  • Interfacing biological material with micro- and nanodevices / Jaime Castillo-León and Winnie E. Svendsen -- Atomic force microscopy for liquid applications / Zachary James Davis -- Manipulation by electrical fields / Maria Dimaki -- Optical manipulation techniques / Kirstine Berg-Sørensen -- Ultrasonic manipulation techniques / Stefano Oberti and Jürg Dual -- 3D biomanipulation using microgrippers / Peter Bøggild -- Magnetic manipulation of biological structures / Maria Dimaki and Winnie E. Svendsen -- Microfluidic manipulation of biological samples / Fridolin Okkels.
  • DNA microarray technology. Introduction / J.R. Pollack -- Comparative genomic hybridization on BAC arrays / B.P. Coe ... [et al.] -- Comparative genomic hybridization on spotted oligonucleotide microarrays / Y.H. Kim and J.R. Pollack -- Comparative genomic hybridization by representational oligonucleotide microarray analysis / R. Lucito and J. Byrnes -- Application of oligonucleotides arrays for coincident comparative genomic hybridization, ploidy status and loss of heterozygosity studies in human cancers / J.K. Cowell and K.C. Lo -- Molecular inversion probe assay for allelic quantitation / H. Ji and K. Welch -- A whole-genome amplification protocol for a wide variety of DNAs, including those from formalin-fixed and paraffin-embedded tissue / P.L. Paris -- Algorithms for calling gains and losses in array CGH data / P. Wang -- Methylation analysis by microarray / D.E. Deatherage ... [et al.] -- Methylation analysis by DNA immunoprecipitation (MeDIP) / E.A. Vucic ... [et al.] -- Combining chromatin immunoprecipitation and oligonucleotide tiling arrays (ChIP-Chip) for functional genomic studies / J. Eeckhoute, M. Lupien and M. Brown -- ChIP-Chip: algorithms for calling binding sites / X.S. Liu and C.A. Meyer -- Mapping regulatory elements by DNaseI hypersensitivity chip (DNase-Chip) / Y. Shibata and G.E. Crawford -- Microarray analysis of DNA replication timing / N. Karnani, C.M. Taylor and A. Dutta -- Integration of diverse microarray data types / K. Salari and J.R. Pollack.
  • Introduction to microarray technologies / Robert S. Matson -- Nucleic acid sample preparation / Robert S. Matson -- Solid-phase substrates for nucleic acid microarrays / Robert S. Matson -- Protein sample preparation for microarrays / Robert S. Matson -- Solid-phase chemistries for protein microarrays / Robert S. Matson -- Protein microarrays : the link between genomics and proteomics / Persis P. Wadia and David B. Miklos -- Bead arrays : an introduction to multiplexed bead-based assays for proteins / Yong Song -- Carbohydrate arrays / Denong Wang -- Lectin microarrays / Masao Yamada -- Printing methods / Todd Martinsky.
  • Manufacturing of microarrays -- Technological platforms for microarray gene expression profiling -- Principles of gene microarray data analysis -- Gaining weights ... and feeling good about it! -- Complementary techniques -- Microarrays for cancer diagnosis and classification -- Gene profiling for the prediction of tumor response to treatment: the case of immunotherapy -- Identification of molecular determinants of tumor sensitivity and resistance to anticancer drugs -- SNP and mutation analysis -- Cancer development and progression -- Gene expression profiling in malignant lymphomas -- Tumor immunology.
  • pt. 1. General microarray technologies -- pt. 2. DNA microarrays -- pt. 3. Protein microarrays -- pt. 4. Cell & tissue microarrays.
  • Microarray technology has made strong progress over the past decade, and there have also been significant changes in application areas, from nucleic acids to proteomics and from research to clinical applications. This book provides a comprehensive overview of microarrays in diagnostics and biomarker development, covering DNA, peptide, protein and tissue arrays. The focus is on entities that are in actual clinical use, or quite close, and on recent developments, such as peptide and aptamer arrays. A further topic is the miniaturisation towards nanoarrays, which is expected to have great potential in clinical applications. Relevant issues of bioinformatics and statistical analysis of array data are discussed in detail, as well as the barriers to the commercialisation of array-based tests and the vexing IP issues involved. Thus, the book should be very useful tor active array users as well as to newcomers seeking to make the best choice between different technologies.
  • Microarrays. 2nd ed. v. 1-2, 2007.
    Springer Protocols
    v.2, 2009 Springer Protocols
    v. 1. Synthesis methods -- v. 2. Applications and data analysis.
  • Bacterial growth -- The outer membrane of gram-negative bacteria and the cytoplasmic membrane -- Peptidoglycan synthesis and cell division -- Cellular permeability -- Allosteric enzymes -- Glycolysis, gluconeogenesis and glycogen synthesis -- The pentose phosphate and Entner-Doudoroff pathways -- The tricarboxylic acid cycle and the glyoxylate bypass -- ATP-generating processes : respiration and fermentation -- Biosynthesis of lipids -- Iron-sulfur proteins -- The archaea -- Methanogens and methylotrophs -- Enzyme induction in catabolic systems -- Transcription : RNA polymerase -- Negative regulation -- Enzyme repression in anabolic pathways -- Positive regulation -- The ribosomes -- The genetic code, the transfer RNAs and the aminoacyl-tRNA-synthetases -- Attenuation -- Riboswitches -- The biological fixation of nitrogen -- How biosynthetic pathways have been established -- The aspartic acid family of amino acids : biosynthesis -- Regulation of the biosynthesis of the amino acids of the aspartic acid family in Enterobacteriaceae -- Other patterns of regulation of the synthesis of amino acids of the aspartate family -- Biosynthesis of the amino acids of the glutamic acid family and its regulation -- Biosynthesis of amino acids derived from phosphoglyceric acid and pyruvic acid -- Selenocysteine and selenoproteins -- Biosynthesis of aromatic amino acids and its regulation -- The biosynthesis of histidine and its regulation -- The biosynthesis of nucleotides -- The biosynthesis of deoxyribonucleotides -- Biosynthesis of some water-soluble vitamins and of their coenzyme forms -- Biosynthesis of carotene, vitamin A, sterols, ubiquinones and menaquinones -- Biosynthesis of the tetrapyrrole ring system -- Biosynthesis of cobalamins including vitamin B12 -- Interactions between proteins and DNA -- Evolution of biosynthetic pathways.
  • Antibiotic resistance : postantibiotic era is here / Vladimir Krcmery -- Current challenges in treating methicillin-resistant Staphylococcus aureus : what are the options? / Noha E.I. Sakka & Ian M . Gould -- Antimicrobial-resistant Streptococcus pneumoniae : trends and management / Michael R. Jacobs -- Emergence and management of drug-resistant enterococcal infections / William R. Miller, Barbara E. Murray & Cesar A. Arias -- Enterobacteriaceae that produce newer b-lactamases / Johann D.D. Pitout -- Extensively drug-resistant tuberculosis : new strains, new challenges / Megan Coffee -- Clinical significance of extended-spectrum b-lactamases / Jesés Rodréguez-Baño, Belén Gutiérrez, Lorena Lépez-Cerero & Alvaro Pascual -- Plasmid-mediated quinolone resistance / José Manuel Rodréguez-Marténez, Maréa Eliecer Cano, Jorge Calvo, Álvaro Pascual & Luis Marténez-Marténez -- Antibiotic resistance in the absence of antimicrobial use / Lucia Pallecchi, Alessandro Bartoloni, Eduardo Gotuzzo & Gian Maria Rossolini -- Resistance in bacteria of the food chain : epidemiology and control strategies / Lina Maria Cavaco & Frank Møller Aarestrup -- Measures to prevent antimicrobial resistance / Vhairi M. Bateman & Ian M. Gould -- Where does novel antibiotics R&D stand among other pharmaceutical products? / Glenn S. Tillotson -- Resistance to antiretroviral drugs / Manuela Colafigli, Simona Di Giambenedetto & Roberto Cauda -- Index.
  • "The field of microbial endocrinology is expressly devoted to understanding the mechanisms by which the microbiota (bacteria within the microbiome) interact with the host ("us"). This interaction is a two-way street and the driving force that governs these interactions are the neuroendocrine products of both the host and the microbiota. Chapters include neuroendocrine hormone-induced changes in gene expression and microbial endocrinology and probiotics. This is the first in a series of books dedicated to understanding how bi-directional communication between host and bacteria represents the cutting edge of translational medical research, and hopefully identifies new ways to understand the mechanisms that determine health and disease"--Publisher's description.
  • Preface: Food--A Necessity and a Threat -- Editor -- Contributors -- Section I. Instances and Nature of Microbial Food Contamination -- 1. PulseNet and Emerging Foodborne Diseases / Efrain M. Ribot, Eija Hyytia-Trees, and Kara Cooper -- 2. Pathogenic Mechanisms of the Enterohemorrhagic
  • Microbial forensics 2005
    ScienceDirect
  • Overview of whole-genome essentiality analysis / Karen Joy Shaw -- Pt. I. Experimental protocols. IA. Populational genome-wide essentiality screens. Transposon-based strategies for the identification of essential bacterial genes / William S. Reznikoff and Kelly M. Winterberg -- Identification and analysis of essential genes in Haemophilus influenzae / Sandy M.S. Wong and Brian J. Akerley -- Transposon site hybridization in Mycobacterium tuberculosis / Jeffrey P. Murry ... [et al.] -- Essential genes in the infection model of Pseudomonas aeruginosa PCR-based signature-tagged mutagenesis / François Sanschagrin, Irena Kukavica-Ibrulj, and Roger C. Levesque -- Whole-genome detection of conditionally essential and dispensable genes in Escherichia coli via genetic footprinting / Michael D. Scholle and Svetlana Y. Gerdes -- Generating a collection of insertion mutations in the Staphylococcus aureus genome using bursa aurealis / Taeok Bae ... [et al.] -- Multipurpose transposon insertion libraries for large-scale analysis of gene function in yeast / Anuj Kumar -- IB. Systematic collections of knockout mutants. How to make a defined near-saturation mutant library. Case 1: Pseudomonas aeruginosa PAO1 / Michael A. Jacobs -- Comparing insertion libraries in two Pseudomonas aeruginosa strains to assess gene essentiality / Nicole T. Liberati ... [et al.] -- The construction of systematic in-frame, single-gene knockout mutant collection in Escherichia coli K-12 / Tomoya Baba and Hirotada Mori -- The applications of systematic in-frame, single-gene knockout mutant collection of Escherichia coli K-12 / Tomoya Baba ... [et al.] -- A novel, simple, high-throughput method for isolation of genome-wide transposon insertion mutants of Escherichia coli K-12 / Takeyoshi Miki, Yoshihiro Yamamoto, and Hideo Matsuda -- High-throughput creation of a whole-genome collection of yeast knockout strains / Angela M. Chu and Ronald W. Davis -- Analysis of genetic interactions on a genome-wide scale in budding yeast: diploid-based synthetic lethality analysis by microarray / Pamela B. Meluh ... [et al.] -- IC. Genome minimization. Scarless engineering of the Escherichia coli genome / Tamás Fehér ... [et al.] -- Minimization of the Escherichia coli genome using the Tn5-targeted Cre/loxP excision system / Byung Jo Yu and Sun Chang Kim -- Construction of long chromosomal deletion mutants of Escherichia coli and minimization of the genome / Jun-ichi Kato and Masayuki Hashimoto -- ID. Conditional knockouts. Identification of essential genes in Staphylococcus aureus by construction and screening of conditional mutant library / Dezhong Yin and Yinduo Ji -- Techniques for the isolation and use of conditionally expressed antisense RNA to achieve essential gene knockdowns in Staphylococcus aureus / Allyn Forsyth and Liangsu Wang -- Introduction of conditional lethal amber mutations in Escherichia coli / Christopher D. Herring -- Pt. II. Bioinformatics. IIA. Statistics. Statistical methods for building random transposon mutagenesis libraries / Oliver Will -- Statistical evaluation of genetic footprinting data / Gábor Balázsi -- Modeling competitive outgrowth of mutant populations : why do essentiality screens yield divergent results? / Alexander I. Grenov and Svetlana Y. Gerdes -- Statistical analysis of fitness data determined by TAG hybridization on microarrays / Brian D. Peyser, Rafael Irizarry, and Forrest A. Spencer -- IIB. Data integration and modeling. Profiling of Escherichia coli chromosome database / Yukiko Yamazaki, Hironori Niki, and Jun-ichi Kato -- Gene essentiality analysis based on DEG, a database of essential genes / Chun-Ting Zhang and Ren Zhang -- Detection of essential genes in Streptococcus pneumoniae using bioinformatics and allelic replacement mutagenesis / Jae-Hoon Song and Kwan Soo Ko -- Design and application of genome-scale reconstructed metabolic models / Isabel Rocha, Jochen Förster, and Jens Nielsen -- Predicting gene essentiality using genome-scale in silico models / Andrew R. Joyce and Bernhard Ø. Palsson -- Comparative approach to analysis of gene essentiality / Andrei L. Osterman and Svetlana Y. Gerdes.
  • A paradigm for commensalism : the role of a specific microbial polysaccharide in health and disease / Kasper, D.L. -- The hygiene hypothesis : do we still believe in it? / Björkstén, B. -- "ABC" of mucosal immunology / Brandtzaeg, P. -- Innate and adaptive immune pathways to tolerance / Thornton, C.A., Morgan, G. -- Hitting the mucosal road in tolerance induction / Wiedermann, U. -- Obesity : extending the hygiene hypothesis / Isolauri, E. ... [et al.] -- Autoimmunity and diet / Cerf-Bensussan, N. -- Eosinophilic esophagitis : example of an emerging allergic manifestation? / Heine, R.G. -- Microbial-host interactions in inflammatory bowel diseases and experimental colitis / Sartor, R.B. -- Development and regulation of immune responses to food antigens in pre- and postnatal life / Renz, H. ... [et al.] -- Novel approaches in treating food allergy using allergens / Rancé, F. -- Allergen avoidance approaches in food allergy management / Koletzko, S., Koletzko, B. -- Role of dietary immunomodulatory factors in the development of immune tolerance / Prescott, S.L. -- Microbial host interactions : selecting the right probiotics and prebiotics for infants / Salminen, S. ... [et al.] -- Probiotics and prebiotics : immunological and clinical effects in allergic disease / Tang, M.L.K. -- Modified proteins in allergy prevention / von Berg, A.
  • Microbial imaging. 1st ed. 2005
    ScienceDirect
  • This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers microbial metagenomics, metatranscriptomics, and metaproteomics, and includes chapters on such topics as in-solution FISH for single cell genome preparation, preparation of BAC libraries from marine microbial community DNA, and preparation of microbial community cDNA for metatranscriptomic analysis in marine plankton. Continues the legacy of this premier serial with quality chapters authored by leaders in the field.
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    "The book starts with dissecting mechanisms underlying viral immune evasion via exploiting the host complement system by vaccinia virus, and by modulating the type 1 interferon response by RNA viruses. Yet another chapter looks into how viroporins expressed by different families of viruses causing influenza A virus, SARS, hepatitis C and HIV interact with several cellular pathways. Understanding of these mechanisms can aid the development of novel potential anti-viral targets. The chapter on tuberculosis discusses the emerging importance of the innate immune mechanisms against Mycobacterium tuberculosis infection and latency. This book has a strong focus on fungal pathogenesis and immunity, starting with virulence and host factors that attain great importance in candidiasis and associated escape tricks of seriously opportunistic fungi. Two chapters on Aspergillus fumigatus elaborate on the pathogenic mechanisms: first discussing A. fumigatus-airway epithelium interaction, followed by fungal and host factors that are paramount in the development of allergic and invasive aspergillosis. In the subsequent chapter, there is a general discussion on the innate and adaptive immune responses against primary and opportunistic fungal pathogens"--Publisher's description.
  • Genome comparison of bacterial pathogens / Wassenaar, T.M. ... [et al.] -- In silico reconstruction of the metabolic and pathogenic potential of bacterial genomes using subsystems / McNeil, L.K., Aziz, R.K. -- The bacterial pan-genome and reverse vaccinology / Tettelin, H. -- 'Guilty by association' : protein-protein interactions (PPIS) in bacterial pathogens / Schauer, K., Stingl, K -- Helicobacter pylori sequences reflect past human migrations / Moodley, Y., Linz, B. -- Helicobacter pylori genome plasticity / Baltrus, D.A., Blaser, M.A., Guillemin, K. -- Genomics of Thermophilic campylobacter species / Gaskin, D.J.H. ... [et al.] -- Adaptation of pathogenic E. coli to various niches : genome flexibility is the key / Brzuszkiewicz, E. ... [et al.] -- Role of horizontal gene transfer in the evolution of Pseudomonas aeruginosa virulence / Qiu, X., Kulasekara, B.R., Lory, S. -- The genus Burkholderia : analysis of 56 genomic sequences / Ussery, D.W. ... [et al.] -- Genomics of host-restricted pathogens of the genus Bartonella / Engel, P., Dehio, C. -- Legionella pneumophila - host interactions : insights gained from comparative genomics and cell biology / Lomma, M. ... [et al.] -- A proteomics view of virulence factors of Staphylococcus aureus / Engelmann, S., Hecker, M. -- Pathogenomics of mycobacteria / Gutierrez, M.C., Supply, P., Brosch, R.
  • Microbial processes and products 2005
    Springer Protocols
  • Diphtheria toxin, diphtheria-related fusion protein toxins, and the molecular mechanism of their action against eukaryotic cells -- Anthrax toxin and genetic aspects regulating its expression -- Shiga toxins and their mechanisms of cell entry -- Cholera toxin: mechanisms of entry into host cells -- ExoU: a cytotoxin delivered by the type III secretion system of pseudomonas aeruginosa -- Staphylococcal alpha-toxin -- S. cerevisiae K28 toxin- a secreted virus toxin of the A/B family of protein toxins -- Kluyveromyces lactis zymocin and other plasmid-encoded yeast killer toxins -- The ustilago maydis killer toxins -- Zygocin- a monomeric protein toxin secreted by virus-infected zygosaccharomyces bailii -- Acidophilic structure and killing mechanism of the pichia farinosa killer toxin SMKT.
  • "Discover important lessons learned about whole organism biology via microbial proteomics This text provides an exhaustive analysis and presentation of current research in the field of microbial proteomics, with an emphasis on new developments and applications and future directions in research. The editors and authors show how and why the relative simplicity of microbes has made them attractive targets for extensive experimental manipulation in a quest for both improved disease prevention and treatment and an improved understanding of whole organism functional biology. In particular, the text demonstrates how microbial proteomic analyses can aid in drug discovery, including identification of new targets, novel diagnostic markers, and lead optimization. Each chapter is written by one or more leading experts in the field and carefully edited to ensure a consistent and thorough approach throughout. Methods, technologies, and tools associated with the most promising approaches are stressed."--Publisher's website.
  • Chapter 1: Overview -- Chapter 2: Performance Criteria -- Chapter 3: Library-dependent Source Tracking Methods -- Chapter 4: Library-Independent Source Tracking Methods -- Chapter 5: Viruses as Tracers of Fecal Contamination -- Chapter 6: Phage Methods -- Chapter 7: Pathogenic Protozoa -- Chapter 8: Chemical-Based Fecal Source Tracking Methods -- Chapter 9: Statistical Approaches for Modeling in Microbial Source Tracking -- Chapter 10: Mitochondrial DNA as Source Tracking Markers of Fecal Contamination -- Chapter 11: Community Analysis-Based Methods -- Chapter 12: Public Perception of and Public Participation in Microbial Source Tracking -- Chapter 13: Use of Microbial Source Tracking in the Legal Arena: Benefits and Challenges -- Chapter 14: Applications of Microbial Source Tracking in the TMDL Process -- Chapter 15: Relating MST Results to Fecal Indicator Bacteria, Pathogens, and Standards -- Chapter 16: Minimizing Microbial Source Tracking at All Costs -- Chapter 17: Environmental Persistence and Naturalization of Fecal Indicator Organisms -- Chapter 18: Agricultural and Rural Watersheds -- Chapter 19: Case Studies of Urban and Suburban Watersheds -- Chapter 20: Beaches and Coastal Environmenta -- Chapter 21: Source tracking in Australia and New Zealand: Case Studies -- Chapter 22: Microbial Source Tracking in China and Developing Nations -- Chapter 23: A National Security Perspective of Microbial Source Tracking -- Chapter 24: Applications of Quantitative Microbial Source Tracking (QMST) and Quantitative Microbial Risk Assessment (QMRA) -- Chapter 25: Food Safety and Implications for Microbial Source Tracking -- Chapter 26: Training Future Scientists: Teaching Microbial Source Tracking (MST) to Undergraduates -- Index.
  • Genetics and genomics of sulfate respiration in desulfovibrio / Judy D. Wall ... [et al.] -- Living on sulfate : three-dimensional structure and spectroscopy of adenosine 5'-phosphosulfate reductase and dissimilatory sulfite reductase / Günter Fritz ... [et al.] -- Respiratory membrane complexes of Desulfovibrio / Inês A. Cardoso Pereira -- Biochemical and evolutionary aspects of eukaryotes that inhabit sulfidic environments / Ursula Theissen, William Martin -- Evolution and ecology of microbes dissimilating sulfur compounds : insights from siroheme sulfite reductases / Alexander Loy, Stephan Duller, Michael Wagner -- Genomic and evolutionary perspectives on sulfur metabolism in green sulfur bacteria / Niels-Ulrik Frigaard, Donald A. Bryant -- Differential-expression proteomics for the study of sulfur metabolism in the chemolithoautotrophic Acidithiobacillus ferrooxidans / Lissette Valenzuela ... [et al.] -- Sulfur and light? History and "thiology" of the phototrophic sulfur bacteria / Hans G. Trüper -- Thiosulfate and sulfur oxidation in purple sulfur bacteria / Frauke Grimm, Bettina Franz, Christiane Dahl -- Sulfur oxidation in Chlorobium tepidum (syn. Chlorobaculum tepidum) : genetic and proteomic analyses / Leong-Keat Chan, Rachael Morgan-Kiss, Thomas E. Hanson -- Structural insights into component SoxY of the thiosulfate-oxidizing multienzyme system of Chlorobaculum thiosulfatiphilum / Jan Stout ... [et al.] -- Redox control of chemotrophic sulfur oxidation of Paracoccus pantotrophus / Cornelius G. Friedrich ... [et al.] -- Bacterial sulfite-oxidizing enzymes : enzymes for chemolithotrophs only? / Ulrike Kappler -- Sulfonates and organotrophic sulfite metabolism / Alasdair M. Cook, Theo H.M. Smits, Karin Denger -- Oxidation of sulfur and inorganic sulfur compounds in Acidianus ambivalens / Arnulf Kletzin -- A novel coenzyme F420 dependent sulfite reductase and a small sulfite reductase in methanogenic archaea / Eric F. Johnson, Biswarup Mukhopadhyay -- Archaeal and bacterial sulfur oxygenase-reductases : genetic diversity and physiological function / Shuang-Jiang Liu -- Diversity of halophilic sulfur-oxidizing bacteria in hypersaline habitats / Dimitry Y. Sorokin -- Sulfur oxidation at deep-sea hydrothermal vents / Stefan M. Sievert ... [et al.] -- Speciation analysis of microbiologically produced sulfur by X-ray absorption near edge structure spectroscopy / Alexander Prange -- Controls on isotope fractionation during dissimilatory sulfate reduction / Joost Hoek, Donald E. Canfield -- Bioprocess engineering of sulfate reduction for environmental technology / Piet N.L. Lens ...[et al.] -- Impact of nitrate on the sulfur cycle in oil fields / Gerrit Voordouw.
  • Computational intelligence in the design of synthetic microbial genetic systems / Jennifer S. Hallinan -- Constraints in the design of the synthetic bacterial chassis / Antoine Danchin and Agnieszka Sekowska -- Social dimensions of microbial synthetic biology / Jane Calvert, Emma Frow -- Bacillus subtilis: model gram-positive synthetic biology chassis / Colin R. Harwood, Suzanne Pohl, Wendy Smith, Anil Wipat -- Engineering microbial biosensors / Lisa Goers, Nicolas Kylilis, Marios Tomazou, Ke Yan Wen, Paul Freemont, Karen Polizzi -- Noise and stochasticity in gene expression: a pathogenic fate determinant / Mikkel Girke Jørgensen, Renske van Raaphorst, Jan-Willem Veening -- Platforms for genetic design automation / Chris J. Myers.
  • Type of human disease by source of the infectious agent -- A history of zoonoses and sapronoses and research into them -- The infection process in zoonoses and sapronoses -- The epidemic process in zoonoses and sapronoses -- Haematophagous arthropods as vectors of diseases -- Vertebrates as hosts and reservoirs of zoonotic microbial agents -- Systematic survey of zoonoses and sapronoses microbial agents.
  • One of the most promising new approaches for the prevention of HIV transmission, particularly for developing countries, involves topical, self-administered products known as microbicides. The development of microbicides is a long and complicated process, and this volume provides an overview of all the critical areas, from the selection of appropriate candidate molecules and their formulation, preclinical and clinical testing for safety and efficacy, strategies for product registration and finally, issues associated with product launch, distribution and access. The book will prove valuable to both those working in the field and all others who are interested in learning more about this product class, which has the potential to significantly impact the future of this devastating epidemic.
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    Problems linked with pathogens in fresh produce, including the associated public health and trade implications, have been reported in a number of countries worldwide. Furthermore, from 1980 to 2004, the global production per annum of fruit and vegetables grew by 94% and they are a critical component of a healthy diet. Reported outbreaks associated with leafy vegetables and herbs have been notable for the wide geographical distribution of the contaminated products, the high numbers of consumers exposed and thus the large number of cases. This meeting addressed the pathways for contamination, survival and persistence of microbiological hazards associated with leafy vegetables and herbs, and the potential management options from primary production through to the consumer.--Publisher's description.
  • Microbiology monographs v. 1-, 2006-
    Springer
  • The second edition of Microbiology of Waterborne Diseases describes the diseases associated with water, their causative agents and the ways in which they gain access to water systems. The book is divided into sections covering bacteria, protozoa, and viruses. Other sections detail methods for detecting and identifying waterborne microorganisms, and the ways in which they are removed from water, including chlorine, ozone, and ultraviolet disinfection. The second edition of this handbook has been updated with information on biofilms and antimicrobial resistance. The impact of global warming and climate change phenomena on waterborne illnesses are also discussed. This book serves as an indispensable reference for public health microbiologists, water utility scientists, research water pollution microbiologists environmental health officers, consultants in communicable disease control and microbial water pollution students. Focuses on the microorganisms of most significance to public health, including E. coli, cryptosporidium, and enterovirus. Highlights the basic microbiology, clinical features, survival in the environment, and gives a risk assessment for each pathogen. Contains new material on antimicrobial resistance and biofilms. Covers drinking water and both marine and freshwater recreational bathing waters.
  • Microbiology of wounds 2010
    CRCnetBASE
    An introduction to the world of microbiology and biofilmology / Steven L. Percival, John G. Thomas, and David Williams -- Human skin and microbial flora / Rose A. Cooper and Steven L. Percival -- An introduction to wounds / Michel H.E. Hermans and Terry Treadwell -- Burn wound management / Michel H.E. Hermans -- Cell biology of normal and impaired healing / Keith Moore -- The microbiology of wounds / Steven L. Percival and Scott E. Dowd -- Types of wounds and infections / Randall D. Wolcott ... [et al.] -- Biofilms and significance to wound healing / Keith F. Cutting ... [et al.] -- Wounds, enzymes, and proteases / Steven L. Percival and Christine A. Cochrane -- Wound healing immunology and biofilms / Emma J. Woods ... [et al.] -- Antimicrobial interventions for wounds / Steven L. Percival, Rose A. Cooper, and Benjamin A. Lipsky -- Wound dressings and other topical treatment modalities in bioburden control / Richard White -- Factors affecting the healing of chronic wounds : an iconoclastic view / Marissa J. Carter and Caroline E. Fife.
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    Basic bacteriology -- Genetics -- Antimicrobial agents -- General medical microbiology -- Gram-positive cocci -- Gram-negative cocci -- Gram-positive and acid-fast bacilli -- Gram-negative bacilli -- Anaerobes -- Spirochetes -- Atypical pathogenic bacteria : mycoplasma, rickettsia, ehrlichia, anaplasma, chlamydia, and chlamydophila -- Virology -- Mycology -- Parasitology -- Random pearls.
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    High Yield Facts -- Physiology and Molecular Microbiology -- Virology -- Bacteriology -- Rickettsiae, Chlamydiae, and Mycoplasms -- Mycology -- Parasitology -- Immunology.
  • Print Material
    1. Virology, immunology, parasitology, mycology -- 2. Bacteriology.
  • Print Material
    v. 1. Virology, immunology, parasitology, mycology -- v. 2. Bacteriology.
  • Microchip methods in diagnostics 2009
    Springer Protocols
    DNA microarrays: an introduction to the technology / Ursula Bilitewski -- Discussion of the applicability of microarrays: profiling of leukemias / Torsten Haferlach ... [et al.] -- Expression profiling using Affymetrix GeneChip microarrays / Herbert Auer, David L. Newsom, and Karl Kornacker -- Genotyping of mutation in the beta-globin gene using DNA microarrays / Martin Dufva and Lena Poulsen -- Antibody-based microarrays / Christer Wingren and Carl A.K. Borrebaeck -- Application of protein ArrayTubes to bacteria, toxin, and biological warfare agent detection / Ralf Ehricht ... [et al.] -- Detection of known allergen-specific IgE antibodies by immunological methods / Barbara I. Fall and Reinhard NieSner -- Peptide microarrays for serum antibody diagnostics / Heiko Andresen and Frank F. Bier -- Microchips for cell-based assays / Martin Dufva -- Bio-cell chip fabrication and applications / Honggu Chun, Dong Soon Lee, and Hee Chan Kim -- Microchip capillary electrophoresis / Elaine T.T. Tay ... [et al.] -- Detection of enteropathogenic Escherichia Coli by microship capillary electrophoresis / Wai S. Law, Sam F.Y. Li, and Larry J. Kricka.
  • Microchip electrophoresis for DNA separation by wire-imprinted microchannels on PMMA substrates / Shu-Hui Chen -- Fabrication of porous polymer monoliths in microfluidic chips for selective nucleic acid concentration and purification / Jay A.A. West and Brent C. Satterfield -- Rapid electrical lysis of bacterial cells in a microfluidic device / Hsiang-Yu Wang ... [et al.] -- On-chip bioassay using immobilized sensing bacteria in three-dimensional microfluidic network / Hirofumi Tani, Koji Maehana, and Tamio Kamidate -- Microchip-based enumeration of human white blood cells / Pierre Floriano ... [et al.] -- Microchip for the diagnosis of cervical cancer / Anja Gulliksen and Frank Karlsen -- DNA microchips toward molecular signatures in cervical cancers / Yick F. Wong ... [et al.] -- Impedimetric detection for DNA hybridization within microfluidic biochips / Louise Lingerfelt ... [et al.] -- Applications of functional protein microarrays: identifying protein/protein interactions in an array format / Matthew A. Coleman ... [et al.] -- A microchip-based assay for interleukin-6 / Nicolaos Christodoulides ... [et al.] -- Allergen microarrays for the diagnosis of specific IgE against components of cow milk and hen egg in a multiplex biochip-based immunoassay / Christian Harwanegg, Sabine Hutter, and Reinhard Hiller -- Surface plasmon resonance imaging on polypyrrole protein chips: application to streptavidin immobilization and immunodetection / Emilie Mercey ... [et al.] -- Protein array-based multiplexed cytokine assays / Cheng C. Wang -- Lectin microarrays for glycoprotein analysis / Lara K. Mahal and Kanoelani Pilobello -- Interaction of HIV RNA with peptides detected by acoustic shear wave sensor operated in an on-line format / Anil Deisingh ... [et al.] -- Microchip-based electrochemical enzyme immunoassays / Madhu Prakash Chatrathi, Greg Collins, and Joseph Wang.
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    v. 1. Blood-vessel interactions -- v. 2. Microcirculation.
  • This book presents a new method for analyzing the structure and function of the biological branching systems of fractal trees, with a focus on microcirculation. Branching systems in humans (vascular and bronchial trees) and those in the natural world (plants, trees, and rivers) are characterized by a fractal nature. To date, fractal studies have tended to concentrate on fractal dimensions, which quantify the complexity of objects, but the applications for practical use have remained largely unexplored. This book breaks new ground with topics that include the human retinal microcirculatory network, oxygen consumption by vascular walls, the Fh raeus-Lindqvist effect, the bifurcation exponent, and the asymmetrical microvascular network. Readers are provided with simple formulas to express functions and a simulation graph with in vivo data. The book also discusses the mechanisms regulating blood flow and pressure and how they are related to pathological changes in the human body. Researchers and clinicians alike will find valuable new insights in these pioneering studies.
  • In vivo target site concentrations are probably the most important determinant of drug effects. Traditionally, linking drug concentrations to drug effects has been accomplished by modelling blood-derived data, mostly because a direct quantification of tissue concentrations has been beyond technical reach. Today, a direct measurement of target site concentrations is possible by employing microdialysis or complementary approaches such as imaging technologies. Microdialysis, initially conceived in the 1970s, has become a standard tool in drug development. This comprehensive overview of current microdialysis technology covers general and disease-specific aspects of microdialysis by international experts in the field. It provides useful information for colleagues in academia and industry who are interested PK-PD aspects of drug development.
  • Microdrop generation 2003
    CRCnetBASE
  • Machine generated contents note: 1 Introduction -- Modeling and Simulation Issues -- Modeling and Simulation Needs -- Computational Architectures for MEFS -- Hierarchical Modeling and Simulation -- Advanced Hierarchical Design Methodology -- Hierarchical Design and Simulation Optimization -- System Design Language Uniformity -- Overview -- 2 Hierarchical Modeling -- MEFS Dynamic Modeling and Simulation at Circuit Level -- Classification of Dynamic System Models -- Fundamental Variables -- Relationships between Fundamental Variables -- Kirchhoffian Networks -- The Equivalent Circuit Modeling Method -- MEFS System-level Modeling and Simulation -- MEFS System-level Modeling -- MEFS System-level Simulation -- Statistical Analysis Capacity -- Conclusion -- 3 SystemC-based Hierarchical Design Environment -- Suitability of Modeling Languages for Hierarchical Design -- VHDL-AMS Suitability for Circuit-level Modeling and Sim- -- ulation -- VHDL Suitability for System-level Modeling and Simula- -- tion -- Performance Language-SLAM -- C/C++ and Matlab -- SystemC -- Building Design Environment with SystemC -- Hierarchical Design Environment -- System-level Modeling Package -- Circuit-level Component Modeling Package -- Numerical Simulation Package -- Optimization/Verification Package -- Conclusion -- 4 System-level Simulation and Performance Evaluation -- MEFS Computing and Architecture -- Architectural Concepts -- Architecture Proposal -- Reconfigurable Architectural Functional Requirements -- Potential Architecture -- Performance Modeling and Simulation -- Hierarchical Modeling and Simulation Methodology -- MEFS Hierarchical Perspective -- Hierarchical Performance Evaluation Strategy -- Modeling and Simulation Language -- Micro-Chemical Handling System -- Stochastic Performance Modeling -- Thermal Catalyzing Process Functionality -- Microvalve Lumped-element Nodal Modeling -- System Performance Analysis and Design Optimization -- Architectural Optimization -- Microsystem Performance Sensitivity Analysis -- Microsystem Performance Estimation with Traffic Variation -- Conclusion -- 5 Circuit-level Optimization -- Simulation Design Methodology -- Bootstrap Method -- Factorial Design -- Optimization Verification -- Subjective Verification -- Objective Verification -- On-target Design Optimization -- Statistical Modeling and Response Analyses -- Statistical Modeling of a Microvalve -- Search for On-target Design Point -- Sensitivity Analysis -- Robust Design Optimization -- Statistical Response Analysis -- Statistical Response Analysis of Microresonators -- Design Optimization of Microvalves -- Application Flexibility Optimization -- Design Approach -- Determining the Performance Flexibility -- Optimization Procedure -- Case Study: Microvalve Modeling and Optimal Design -- Conclusion -- 6 Performance Evaluation -- Introduction -- Polymerase Chain Reaction (PCR) -- PCR Detection for DNA Concentration -- PCR Purification -- Acquisition Assumption -- Continuous-flow PCR System -- Three-way Microvalve -- Sequential Continuous-flow PCR System -- Detectable PCR System -- Reconfigurable PCR System -- Droplet-based PCR System -- A Droplet-based PCR System -- Physical Implementation -- Comparison between Continuous-flow PCR and Droplet PCR -- System Design Complexity -- Performance Evaluation -- Scheduling of Microfluidic Operations for Reconfigurable Two-Dimensional -- Electrowetting Arrays -- Introduction -- Two-dimensional Electrowetting Array -- Schedule Optimization -- Droplet-based PCR Systems -- 7 Conclusion -- A VHDL Queuing Model -- B Hierarchical Environment with SystemC -- References -- Index.
  • Overview of advances in microfluidics and microfabrication / Shelley D. Minteer and Christine M. Moore -- Introduction to microfabrication techniques / Rabih Zaouk, Benjamin Y. Park, and Marc J. Madou -- Fabrication ofpolydimethylsiloxane microfluidics using SU-8 molds / Rabih Zaouk, Benjamin Y. Park, and Marc J. Madou -- Fabrication of microelectrodes using the lift-off technique / Benjamin Y. Park, Rabih Zaouk, and Marc J. Madou -- Laser ablation as a fabrication technique for microfluidic devices / Emanual A. Waddell -- Reversible, room temperature bonding of glass devices for microfluidics / Loranelle L. Lockyear -- Solid phase extraction in packed beds on glass microdevices / Loranelle L. Lockyear -- Fabrication of micromachined magnetic particle separators for bioseparation in microfluidic systems / Jin-Woo Choi -- Hydrogel-immobilized antibodies for microfluidic immunoassays: hydrogel immunoassay / Gloria Thomas ... [et al.] -- Polymerase chain reaction in miniaturized systems : big progress in little devices / Kalee D. Spitzack and Victor M. Ugaz -- Polymerase chain reaction on microchips / Maria C. Carles and Nikolaus J. Sucher -- A sensitive sandwich DNA array using fluorescent nanoparticle probes / Xiajun Zhao, David T. Pierce, and Yanfu Huan -- Microfluidic ethanol biobatteries on a microchip / Shelley D. Minteer and Christine M. Moore -- Microfluidic chambers for cell migration and neuroscience research / Anne M. Taylor, Seog Woo Rhee, and Noo Li Jeon -- Microtextured polydimethylsiloxane substrates for culturing mesenchymal stem cells / Erik T.K. Peterson and Ian Papautsky -- Contraction study of a single cardiac muscle cell in the microfluidic chip / Xiujun (James) Li and Paul C.H. Li -- Microscale inegrated sperm sorter / Yaokuang Chung ... [et al.].
  • Expression of exogenous mRNA in Xenopus laevis embryos for the study of cell cycle regulation / Jill C. Sible and Brian N. Wroble -- Use of luciferase chimaera to monitor PLC[zeta] expression in mouse eggs / Karl Swann ... [et al.] -- Analysis of 14-3-3 family member function in Xenopus embryos by microinjection of antisense morpholino oligos / Jeffrey M.S. Lau and Anthony J. Muslin -- A microinjectable biological system, the Xenopus oocyte, as an approach to understanding signal transduction protein function / Katia Cailliau and Edith Browaeys-Poly -- Combining microinjection and immunoblotting to analyse MAP kinase phosphorylation in single starfish oocytes and eggs / David J. Carroll and Wei Hua -- Analysis of signaling pathways in zebrafish development by microinjection / William H. Kinsey -- Protein inhibition by microinjection and RNA-mediated interference in tissue culture cells : complementary approaches to study protein function / Jane R. Stout, Rania S. Rizk, and Claire E. Walczak -- DNA delivery by microinjection for the generation of recombinant mammalian cell lines / Sebastien Chenuet ... [et al.] -- Bacteriophage [phi]C31 integrase mediated transgenesis in Xenopus laevis for protein expression at endogenous levels / Bryan G. Allen and Daniel L. Weeks -- Germline transformation of Caenorhabditis elegans by injection / Pavan Kadandale, Indrani Chatterjee, and Andrew Singson -- Quantitative microinjection of mouse oocytes and eggs / Douglas Kline -- Microinjection of follicle-enclosed mouse oocytes / Laurinda A. Jaffe ... [et al.] -- Functional studies of regulatory genes in the sea urchin embryo / Vincenzo Cavalieri, Maria Di Bernardo, and Giovanni Spinelli -- Exploring the cytoskeleton during intracytoplasmic sperm injection in humans / Vanesa Y. Rawe and Héctor Chemes -- Somatic cell nuclear transfer in the mouse / Satoshi Kishigami and Teruhiko Wakayama.
  • Micromammals and macroparasites : who is who and how they interact? / S. Morand ... [et al.] -- Digenean trematodes / C. Feliu ... [et al.] -- Cestodes of small mammals : taxonomy and life cycles / B.B. Georgiev, R.A. Bray and D.T.J. Littlewood -- Nematodes / S. Morand, S. Bouamer and J.-P Hugot -- Acanthocephalans / A. Ribas and J.C. Casanova -- Taxonomy, host associations, life cycles and vectorial importance of ticks parasitizing small mammals / L.A. Durden -- Mesostigmatid mites as parasites of small mammals : systematics, ecology, and the evolution of parasitic associations / A.P.G. Dowling -- Taxonomy, life cycles and the origin of parasitism in trombiculid mites / A.B. Shatrov and J.I. Kudryashova -- Blood-sucking lice (Anoplura) of small mammals : true parasites / K.C. Kim -- Fleas : permanent satellites of small mammals / S.G. Medvedev and B.R. Krasnov -- Bat flies : obligate ectoparasites of bats / C.W. Dick and B.D. Patterson -- Patterns of macroparasite diversity in small mammals / B.R. Krasnov, R. Poulin and S. Morand -- Patterns of host specificity in parasites exploiting small mammals / R. Poulin, B.R. Krasnov and S. Morand -- Coevolution of macroparasites and their small mammalian hosts : cophylogeny and coadaptation / J.-P. Hugot -- Comparative phylogeography : the use of parasites for insights into host history / Cj.M. Nieberding and S. Morand -- Insularity and micromammal-macroparasite relationships / E. Magnanou and S. Morand -- Models for host-macroparasite interactions in micromammals / R. Rosà ... [et al.] -- Transmission ecology and the structure of parasite communities /aI.M. Cattadori ... [et al.] -- Effect of macroparasites on the energy budget of small mammals / A.A. Degen -- Immunogenetics of micromammal-macroparasite interactions / N. Charbonnel, J. Goüy de Bellocq and S. Morand -- Interactions among immune, endocrine, and behavioural response to infection / Z.M. Weil, L.B. Martin II and R.J. Nelson -- Behaviour, life history strategies and parasite infection in rodents / C.J. Barnard and J.M. Behnke -- Nematode zoonoses / J.C. Casanova, A. Ribas and J.M. Segovia -- Rodents as definitive hosts of Schistosoma, with special reference to S. mansoni transmission / J.-M. Duplantier and M. Sene -- Towards understanding the impacts of environmental variation on Echinococcus multilocularis transmission / D.R.J. Pleydell ... [et al.] -- Parasites and pest population management / H. Leirs and G.R. Singleton -- Biological conservation and parasitism / P. Christe, S. Morand and J. Michaux -- Global changes and the future of micromammal-macroparasite interactions / S. Morand, R. Poulin and B.R. Krasnov.
  • ch. 1. From macrooptics to microoptics: an overview, p. 1-12 -- ch. 2. Optical components with small dimensions, p. 13-32 -- ch. 3. Lithographic fabrication technology, p. 33-76 -- ch. 4. Measurement and characterization of microoptics, p. 77-92 -- ch. 5. Refractive microoptics, p. 93-131 -- ch. 6. Diffractive microoptics, p. 133-180 -- ch. 7. Integrated waveguide optics, p. 181-205 -- ch. 8. Microoptical systems, p. 207-228 -- ch. 9. Optoelectronic devices and smart pixel arrays, p. 229-250 -- ch. 10. Array illuminators, p. 251-276 -- ch. 11. Microoptical components for beam shaping, p. 277-303 -- ch. 12. Microoptics for optical information technology, p. 305-336 -- ch. 13. Microoptics in optical design, p. 337-353 -- ch. 14. Novel directions, p. 355-381.
  • Biotechnology and the public health response to bioterrorism -- Historical perspectives of microbial bioterrorism -- The infectious disease physician and microbial bioterrorism -- Modulation of innate immunity to protect against biological weapon threat -- Smallpox: pathogenesis and host immune responses relevant to vaccine and therapeutic strategies -- Bacillus anthracis: agent of bioterror and disease -- Tularemia pathogenesis and immunity -- Brucella and bioterrorism -- Pneumonic plague -- Coxiella burnetii, Q fever, and bioterrorism -- Genomic and proteomic approaches against Q fever -- Rickettsia rickettsii and other members of the spotted fever group as potential bioweapons.
  • Machine generated contents note: ch. 1 Microorganisms in air -- 1.1.Microorganisms in outdoor air / B. Flannigan -- 1.2.Microorganisms in indoor air / B. Flannigan -- 1.3.Pollen in indoor air / A. Rantio-Lehtimaki -- ch. 2 Microorganisms in homes and work environments -- 2.1.Microbial growth in indoor environments / J.D. Miller -- 2.2.Bacteria and other bioaerosols in industrial workplaces / J.R.M. Swan -- 2.3.Remediation and control of microbial growth in problem buildings / P.R. Morey -- ch. 3 Airborne microorganisms and disease -- 3.1.Allergenic microorganisms and hypersensitivity / J.H. Day -- 3.2.Occupational respiratory disease: hypersensitivity pneumonitis and other forms of interstitial lung disease / B. Flannigan -- 3.3.Respiratory tract infections caused by indoor fungi / R.C. Summerbell -- ch. 4 Microbiological investigation of indoor environments -- 4.1.Mycological investigations of indoor environments / J.D. Miller -- 4.2.Molecular methods for bioaerosol characterization / J.A. Scott -- 4.3.Isolation and identification of fungi / J. Houbraken -- 4.4.Analysis of microbial volatile organic compounds / T.J. Ryan -- 4.5.Analysis for toxins and inflammatory compounds / J.D. Miller -- 4.6.Interpreting sampling data in investigations of indoor environments: selected case studies / P.R. Morey -- ch. 5 Common and important species of Actinobacteria and fungi in indoor environments -- Common and important species of fungi and actinomycetes in indoor environments / J.D. Miller -- Descriptions and illustrations of common fungi and actinomycetes.
  • Pt. A ScienceDirect
    Pt. B ScienceDirect
    Pt. C ScienceDirect
    "Micropatterning refers generally to techniques which provide an experimental control over the chemical, physical, or geometrical properties of materials at the micron or submicron scale, and are thus used to produce spatial patterns of these properties. These techniques, which were often originally designed for application in microelectronics, have spread over most areas of science, including biology. They have proved particularly useful for cell biology, bridging the gap between the Petri-dish and complex 3D assays and tissues."--Preface.
  • Microperimetry and Multimodal Retinal Imaging: the Fundamentals: Functional Evaluation of the Retina: an Introduction -- Retinal Fixation and Microperimetry -- Microperimetry: technical remarks -- OCT/SLO Microperimetry and Correlates -- Scotopic microperimetry -- Multimodal retinal imaging: an Introduction. Clinical Applications of Microperimetry and Multimodal Retina Imaging: Early and Intermediate Age-Related Macular Degeneration -- Geographic atrophy -- Neovascular age-related macular degeneration -- Retinal Pigment Epithelium and Choroid Graft -- Macular Telangiectasia Type 2 -- Diabetes and Retinal Vascular Disorders -- Myopia -- Retinal Dystrophies -- Disorders of the vitreoretinal interface -- Inflammatory chorio-retinal diseases -- Toxic retinopathies -- Glaucoma. The contribution to visual rehabilitation: Low vision: diagnosis and rehabilitation.
  • MicroRNA Biogenesis and Cancer / Julia Winter, Sven Diederichs -- Computational Identification of miRNAs Involved in Cancer / Anastasis Oulas, Nestoras Karathanasis, Panayiota Poirazi -- The Principles of MiRNA-Masking Antisense Oligonucleotides Technology / Zhiguo Wang -- The Concept of Multiple-Target Anti-miRNA Antisense Oligonucleotide Technology / Zhiguo Wang -- Modulation of MicroRNAs for Potential Cancer Therapeutics / Wei Wu -- Detection of MicroRNAs in Cultured Cells and Paraffin-Embedded Tissue Specimens by In Situ Hybridization / Ashim Gupta, Yin-Yuan Mo -- MicroRNA Northern Blotting, Precursor Cloning, and Ago2-Improved RNA Interference / Julia Winter, Sven Diederichs -- miRNA Profiling on High-Throughput OpenArray System / Elena V. Grigorenko, Elen Ortenberg, James Hurley, Andrew Bond, Kevin Munnelly -- Silicon Nanowire Biosensor for Ultrasensitive and Label-Free Direct Detection of miRNAs / Guo-Jun Zhang -- High-Throughput and Reliable Protocols for Animal MicroRNA Library Cloning / Caide Xiao -- MicroRNA Regulation of Growth Factor Receptor Signaling in Human Cancer Cells / Keith M. Giles, Andrew Barker, Priscilla M. Zhang, Michael R. Epis, Peter J. Leedman -- Epigenetic Regulation of MicroRNA Expression in Cancer / Hani Choudhry, James W. Catto -- In Vitro Functional Study of miR-126 in Leukemia / Zejuan Li, Jianjun Chen -- Prediction of the Biological Effect of Polymorphisms Within MicroRNA Binding Sites / Debora Landi, Roberto Barale, Federica Gemignani, Stefano Landi -- The Guideline of the Design and Validation of MiRNA Mimics / Zhiguo Wang -- Analysis of Targets and Functions Coregulated by MicroRNAs / Shu-Jen Chen, Hua-Chien Chen -- Utilization of SSCprofiler to Predict a New miRNA Gene / Anastasis Oulas, Panayiota Poirazi -- MicroRNA Profiling Using Fluorescence-Labeled Beads: Data Acquisition and Processing / Thomas Streichert, Benjamin Otto, Ulrich Lehmann.
  • "This book reflects the current state of knowledge about the role of microRNAs in the formation and progression of solid tumours. The main focus lies on computational methods and their applications in combination with cutting edge experimental techniques that are used to approach all aspects of microRNA regulation in cancer. The use of high-throughput quantitative techniques makes an integrative experimental and computational approach necessary. This book will be a resource for researchers starting out with microRNA research, but is also intended for the experienced researcher who wants to incorporate concepts and tools from systems biology and bioinformatics into his work. Bioinformaticians and modellers are provided with a general perspective on microRNA biology, and the state-of-the-art in computational microRNA biology." --Publisher's description.
  • MicroRNA in cancer 2013
    Springer
    The field of microRNA biology is really emerging in the last couple of years. Several investigators highlighted the importance of miRNAs in cancer. Although there is so much literature on microRNAs exist, a comprehensive book is still not available. Thus this book will be a great use to the scientists in the field of cancer biology. In addition, this book will be a good source of information for undergraduate, graduate students who want to develop their research careers in cancer biology.
  • MicroRNA methods 2007
    ScienceDirect
  • Measurement and interpretation of microRNA expression profiles / Bo Curry and Robert Ach -- MicroRNA expression analysis by LNA enhanced microarrays / Rolf Sokilde ... [et al.] -- Analysis and QC for real-time OPCR arrays of human microRNAs / Dirk P. Ditmer ... [et al.] -- Massively parallel microRNA profiling in the haematologic malignancies / Ryan D. Morin ... [et al.] -- Who dunit? microRNAs involved in prostate cancer / Chang Hee Kim -- Intronic microRNA : creation, evolution and regulation / Sailen Barik and Titus Barik -- miRome architechture and genomic instability / Konrad Huppi ... [et al.] -- Interconnection of microRNA and transcription factor-mediated regulatory networks / Yiming Zhou -- Analysis of microRNA profiling data with systems biology tools / Yuriy Gusev ... [et al.] -- Mathematical and computational modeling of post-transriptional gene regulation by microRNAs / Raya Khanin and Desmond J. Higham.
  • MicroRNA protocols 2006
    Springer Protocols
  • The book serves as a comprehensive resource for scientists and clinicians studying the role of non-coding RNAs in inflammation (viral infections, wound inflammation), human inflammatory diseases (i.e. rheumatoid arthritis, Crohnℓ́ℓs disease, diabetes), and innate immunity. It provides a universal reference work comprising both basic and specialized information. Given that ncRNAs represent new therapeutic targets, this volume will also be of interest to industrial biomedical researchers and those involved in drug development.
  • A rapid, quantitative assay for direct detection of microRNAs and other small RNAs using splinted ligation -- Normalization of microRNA quantitative RT-PCR data in reduced scale experimental designs -- MicroRNA detection in bone marrow cells by LNA-FISH -- Measuring microRNA expression in size-limited facs-sorted and microdissected samples -- MicroRNA cloning from cells of the immune system -- High-throughput profiling in the hematopoietic system -- Construction of small RNA cDNA libraries for deep sequencing -- MicroRNA-profiling in formalin-fixed paraffin-embedded specimens -- Expression of miRNAs in lymphocytes : A review -- Mouse models for miRNA expression: The ROSA26 locus -- Regulation of monocytopoiesis by microRNAs -- MicroRNA activity in B lymphocytes -- Isolation and characterization of microRNAs of human mature erythrocytes -- Stable overexpression of miRNAs in bone marrow-derived murine mast cells using lentiviral expression vectors -- Monitoring microRNA activity and validating microRNA targets by reporter-based approaches -- Lentivirus-mediated antagomir expression -- Solution structure of miRNA:mRNA complex -- MiRNA editing -- Computational prediction of microRNA targets -- Large-scale integration of microRNA and gene expression data for identification of enriched microRNA-mRNA associations in biological systems -- Identification and validation of the cellular targets of virus-encoded microRNAs.
  • "MicroRNAs are small, non-coding RNA molecules that interact with target mRNAs to modulate their translation. They are now recognized as widespread and critical regulators of gene expression in the cell. This book is aimed at both industry- and academic-based researchers in the Biopharmaceutical production space who wish to learn more about these fascinating molecules..."--Page [4] of cover.
  • 1 -- MicroRNAs in Cancer (An Overview) -- 2. The Role of MicroRNAs in Lung Cancer Development, Progression, and Metastasis -- 3. MicroRNAs in Breast Cancer -- 4. MicroRNAs in Colorectal Cancer -- 5. MicroRNAs in Gastric Cancer -- 6. MicroRNAs in Prostate Cancer: A Possible Role as Novel Biomarkers and Therapeutic Targets?- 7. MicroRNAs in Hepatocellular Carcinoma -- 8. MicroRNAs in Cervical Carcinoma -- 9. MicroRNAs in Esophageal Cancer -- 10. MicroRNAs in Bladder Cancer -- 11. MicroRNAs in Lymphoma -- 12. MicroRNAs in Leukemia -- 13. MicroRNAs in Pancreatic Cancer: Potential Interests as Biomarkers and Therapeutic Tools -- 14. MicroRNAs in Epithelial Ovarian Cancer -- 15. MicroRNAs in Brain Tumors -- 16. MicroRNAs and Cancer Stem Cells -- 17. MicroRNAs in Cancer Invasion and Metastasis -- 18. MicroRNAs in Predicting Radiotherapy and Chemotherapy Response -- 19. Role of MicroRNAs in Anti-cancer Drug Resistance -- 20. MicroRNAs and Cancer Metabolism -- 21. MicroRNAs as Blood-based Biomarkers of Cancer -- 22. RNAi-based Approaches to the Treatment of Brain Tumors.
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    "This book elucidates the development of the surgical therapy of ear diseases from antiquity to the middle ages and modern times up to the present."--Preface.
  • ch. 1. Light Microscopy, p. 1-145 -- ch. 2. Electron Microscopy, p. 147-286 -- ch. 3. Other Microscopical Methods and their Application Potential, p. 287-319.
  • Getting Excel data into Access -- Analyzing Excel data with Access queries -- Sprucing up Excel data with Access reports -- Using PivotTables and PivotCharts in Access -- Getting Access data into Excel -- Leveraging macros in Excel and Access -- VBA fundamentals -- Using VBA to move data between Excel and Access -- Exploring Excel and Access automation -- Integrating Excel and Access with XML -- Integrating Excel and other Office applications.
  • Print Material
  • 1. Understanding Microsoft Access -- 2. Building an Access 2007 Desktop Application -- 3. Creating Forms and Reports in a Desktop Application -- 4. Automating an Access Application -- 5. Linking Access and the Web -- 6. After Completing Your Application -- 7. Designing an Access Project -- 8. Articles.
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  • Microsoft Office home and student 2007 step by step 2008
    books24x7, SUNet ID login required.
  • Print Material
    PART 1: WORD 2007: STARTING YOUR DOCUMENT WITH LATEST AND GREATEST: Room to create with Office Word 2007 -- Document creation with Word 2007 -- Mastering page setup and pagination -- Formatting documents using templates -- Applying themes for a professional look -- PART 2: WORKING WITH CONTENT: Mastering document fundamentals -- Honing document navigation skills -- Working with building blocks and other text tools -- Refining with research services and reference tools -- Outlining documents for clarity and structure -- PART 3: VISUAL ELEMENTS: TABLES, CHARTS, DIAGRAMS, PICTURES: Organizing concepts in tables -- Showcasing data with SmartArt and charts -- Adding visual impact with pictures, drawings, and WordArt -- PART 4: PROFESSIONAL POLISH: LISTS, STYLES, BACKGROUNDS, AND BORDERS: Aligning information and formatting paragraphs and lists -- Using styles to increase your formatting power -- Formatting layouts using backgrounds, watermarks, and text boxes -- Commanding attention with borders and shading -- PART 5: COLLABORATIVE PROJECTS: SHARED DOCUMENTS, REVISIONS, SECURITY: Sharing documents and collaborating online -- Revising documents using markup tools -- Addressing document protection and security issues -- PART 6: COMPLEX DOCUMENTS: SECTIONS, MASTER DOCUMENTS, AND REFERENCES: Formatting columns and sections for advanced text content -- Configuring references -- Generating first-class tables of contents and reference tables -- Creating effective indexes -- PART 7: PUBLISHING WORD TO THE WORLD: Printing with precision -- Blogging from Word 2007 -- Performing mail merges -- Customizing documents with content controls -- Working with XML -- Working with macros and VBA.
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  • Microsoft Outlook 2007 bible 2007
    ProQuest Safari
    2007 books24x7, SUNet ID login required.
  • 2007 books24x7, SUNet ID login required.
  • Microsoft Project 2007 bible 2007
    books24x7, SUNet ID login required.
    2007 ProQuest Safari
  • Microsoft Word 2007 bible 2007
    ProQuest Safari
    2007 books24x7, SUNet ID login required.
  • 1. Microspheres for enzyme immobilization / Fei Gao, Yuxia Wang, and Guanghui Ma -- 2. Microspheres for cell culture / Weiqing Zhou, Guanghui Ma, and Zhiguo Su -- 3. Microcapsules for cell transplantation : design, preparation, and application / Guojun Lv, Ying Zhang, Mingqian Tan, Hongguo Xie, and Xiaojun Ma -- 4. Microspheres for the separation and refolding of proteins with an emphasis on particles made of agarose / Jan-Christer Janson -- 5. Microspheres for separation of bioactive small molecules / Fangling Gong, Guifeng Zhang, and Zhiguo Su -- 6. Microspheres for separation of PEG-modified biomolecules / Yongdong Huang, Yanqin Zhai, and Zhiguo Su -- 7. Microspheres for solid-phase organic synthesis / Jing Zhang and Zhiguo Su -- 8. Microspheres for solid-phase modification of proteins / Tao Hu and Zhiguo Su -- 9. Microspheres and microcapsules for protein drug delivery / Lianyan Wang, Tingyuan Yang, and Guanghui Ma -- 10. Micro/nanospheres for gene drug delivery / Jie Wu and Guanghui Ma -- 11. Microspheres for targeting delivery of anticancer drugs / Wei Wei, Zhanguo Yue, Hua Yue, and Guanghui Ma -- 12. Microspheres for targeting delivery to brain / Chen Jiang, Xinguo Jiang, Yang Liu, Kun Shao, and Rongqin Huang -- 13. Nano/microspheres in bioimaging and medical diagnosis / Xiaohui Li and Chunying Chen -- 14. Affinity nanoparticles for detection / Haruma Kawaguchi and Hiroshi Handa.
  • Guy N. Elston, Laurence J. Garey: The cytoarchitectonic map of Korbinian Brodmann: Arealisation and circuit specialization -- Lazaros C. Triarhou: The cytoarchitectonic map of Constantin von Economo and Georg N. Koskinas -- Rudolf Nieuwenhuys: The myeloarchitectonic studies on the human cerebral cortex of the Vogt -- Vogt school, and their significance for the interpretation of functional neuroimaging data -- Bruce Fischl: Estimating the location of Brodmann Areas from cortical folding patterns using histology and ex vivo MRI -- Simon B. Eickhoff, Danilo Bzdok: Database-driven identification of functional modules in the cerebral cortex -- Robert Turner: Where matters: New approaches to brain analysis -- Robert Turner: MRI methods for in-vivo cortical parcellation -- Nicholas A. Bock, Afonso C. Silva: Visualizing myeloarchitecture in vivo with magnetic resonance imaging in common marmosets (Callithrix jacchus) -- Stefan Geyer: High-field magnetic resonance mapping of the border between primary motor (area 4) and somatosensory (area 3a) cortex in ex-vivo and in-vivo human brains.
  • Male Infertility Microsurgical Training / Philip S. Li, Ranjith Ramasamy and Marc Goldstein -- Microsurgery Training: What Should a Resident Know? Should All Microsurgeons be Fellowship Trained? / Ethan Grober and Peter N. Kolettis -- Microsurgical Subinguinal Varix Ligation: Techniques and Technical Pearls / Joshua A. Bodie and Jay I. Sandlow -- Vasovasostomy Techniques for Microsurgery Specialists / Kalen Rimar, Landon Trost and Robert E. Brannigan -- Epididymovasostomy: Tips and Tricks of the Trade / James F. Smith and Ajay K. Nangia -- Sperm Retrieval Techniques in Obstructive Azoospermia: MESA, PESA, and TESA / Anand Shridharani and Jay I. Sandlow -- Microsurgical Testicular Sperm Extraction: Technical Considerations / Peter N. Schlegel -- Noninfertility Scrotal Microsurgery / Akanksha Mehta and Marc Goldstein -- Testis-Sparing Surgery for Testicular Masses / Oleksandr Stakhovskyi and Michael A. S. Jewett -- Robotic Microsurgery for Male Infertility / Sijo J. Parekattil, Ahmet Gudeloglu and Jamin V. Brahmbhatt -- The Role of Microsurgical Reconstruction in the Era of ICSI / Karen Baker and Edmund Sabanegh Jr -- Tubal Microsurgery / Jeffrey M. Goldberg and Tommaso Falcone -- Microsurgical Penile Revascularization, Replantation, and Reconstruction / Jeffrey Lee Rosenblum and Arthur L. Burnett.
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  • This book provides the anatomy of the posterior fossa, together with the main associated surgical techniques, which are detailed in numerous photographs and step-by-step color illustrations. The text presents approaches and surgical techniques such as the trans-cerebellomedullary fissure approach and its variation to the fourth ventricle, as well as the cerebellomedullary cistern, infratentorial lateral supracerebellar approach to the fifth cranial nerve in the upper cerebellopontine angle, infrafloccular approach to the root exit zone of the seventh cranial nerve, transcondylar fossa approach through the lateral part of the foramen magnum, and the stitched sling retraction technique utilized during microvascular decompression procedures for trigeminal neuralgia and hemifacial spasm. It also describes in detail the bridging veins of the posterior fossa, especially the petrosal vein, and bridging veins to the tentorial sinuses, which can block approaches to the affected area. The original Japanese version of this work was published 8 years ago, and has established itself as a trusted guide, especially among young neurosurgeons who need to study various surgical approaches and techniques. In the course of being translated into English, some sections have been revised and new information has been added. The author hopes that the book will help neurosurgeons around the world perform safer operations with confidence.
  • "Remarkable progress in the development of new concepts and techniques used in reconstructive surgery of microtia/atresia of the external auditory canal (EAC) has been made since the beginning of the 21st century. Helical computed tomography has made a three-dimensional reconstruction of the soft tissue of the temporal bone surface and the cranium possible, and has laid the groundwork for a collaboration between plastic surgeons and otologists. This book presents the latest findings on reconstructive surgery performed jointly by plastic surgeons and otologists. Based on this concept, information on diagnosis, surgical procedures, outcomes, long-term results and psychology is discussed. Collaborative surgery offers advantages not only in terms of a better reconstruction of morphology and function, but also in terms of the lower number of surgical procedures required which reduces the psychological pressure and economic burden on patients."--Publisher's website.
  • Microtubule protocols 2007
    Springer Protocols
  • Site-specific fluorescent labeling of tubulin / Kamalika Muhkerjee, Susan L. Bane -- Measuring microtubule persistence length using a microtubule gliding assay / Douglas S. Martin -- Structural studies of the doublecortin family of MAPs / Frank Fourniol, Mylène Perderiset, Anne Houdusse, Carolyn Moores -- Detection and quantification of microtubule detachment from centrosomes and spindle poles / Anutosh Ganguly, Hailing Yang, Fernando Cabral -- Regulation of tubulin expression by micro-RNAs : implications for drug resistance / Sharon Lobert, Mary E. Graichen -- Determining the structure-mechanics relationships of dense microtubule networks with confocal microscopy and magnetic tweezers-based microrheology / Yali Yang, Megan T. Valentine -- Studying mitochondria and microtubule localization and dynamics in standardized cell shapes / Andrea Pelikan, James Sillibourne, Stephanie Miserey-Lenkei, Frederique Carlier-Grynkorn, Bruno Goud, Phong T. Tran -- Going solo : measuring the motions of microtubules with an in vitro assay for TIRF microscopy / Kris Leslie, Niels Galjart -- Analysis of microtubules in isolated axoplasm from the squid giant axon / Yuyu Song, Scott T. Brady -- Imaging GTP-bound tubulin : from cellular to in vitro assembled microtubules / Hélène de Forges, Antoine Pilon, Christian Poüs, Franck Perez -- Tubulin-specific chaperones : components of a molecular machine that assembles the ... heterodimer / Guoling Tian, Nicholas J. Cowan -- Heterotrimeric G proteins and microtubules / Witchuda Saengsawang, Mark M. Rasenick -- Purification and biophysical analysis of microtubule-severing enzymes in vitro / Juan Daniel Diaz-Valencia, Megan Bailey, Jennifer L. Ross -- Measurement of in vitro microtubule polymerization by turbidity and fluorescence / Matthew Mirigian, Kamalika Mukherjee, Susan L. Bane, Dan L. Sackett -- Live-cell imaging of microtubules and microtubule-associated proteins in arabidopsis thaliana / Jessica Lucas -- Investigating tubulin posttranslational modifications with specific antibodies / Maria M. Magiera, Carsten Janke -- Purification and assembly of bacterial tubulin BtubA/B and constructs bearing eukaryotic tubulin sequences / José M. Andreu, María A. Oliva -- Microtubule-associated proteins and tubulin interaction by isothermal titration calorimetry / P.O. Tsvetkov, P. Barbier, G. Breuzard, V. Peyrot, F. Devred -- Methods for studying microtubule binding site interactions : zampanolide as a covalent binding agent / Jessica J. Field, Enrique Calvo, Peter T. Northcote, John H. Miller, Karl-Heinz Altmann, José Fernando Díaz -- Studying kinetochore-fiber ultrastructure using correlative light-electron microscopy / Daniel G. Booth, Liam P. Cheeseman, Ian A. Prior, Stephen J. Royle -- Fluorescence-based assays for microtubule architecture / Susanne Bechstedt, Gary L. Brouhard -- Structure-function analysis of yeast tubulin / Anna Luchniak, Yusuke Fukuda, Mohan L. Gupta -- Using MTBindingSim as a tool for experimental planning and interpretation / Julia T. Philip, Aranda R. Duan, Emily O. Alberico, Holly V. Goodson -- Imaging individual spindle microtubule dynamics in fission yeast / Judite Costa, Chuanhai Fu, Viktoriya Syrovatkina, Phong T. Tran.
  • The middle ear plays a vital role in the sense and sensitivity of hearing. Of the various characteristics that distinguish mammals from other vertebrates, several pertain specifically to the middle-ear system, such as the presence of three middle-ear bones and the four-layer composite structure of the tympanic membrane. The Middle Ear attempts to elucidate the role this system plays in sound transmission, as viewed from both scientific and clinical perspectives.
  • Middle ear surgery 2006
    Springer
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  • Midface surgery 2009
    ClinicalKey
    Anatomy of the upper and lower eyelids -- Anchoring technique for browlifting -- Correction of upper lid ptosis -- Correction of the tear through deformity with hyaluronic acid -- Lower lid blepharoplasty with fat grafts for correction of the tear though -- No-touch lower blepharoplasty -- Alloplastic augmentation to improve blepharoplasty and midfacial results -- Orbital aging and harmony in orbital rejuvenation -- Evolution of the subperiosteal midface lift -- Midface elevation: one single suture -- Is the transpalpebral approach to the upper and midface rejuvenation a safe method? -- A personal approach to upper and lower blepharoplasty -- Transconjuctival deep-plane midface rejuvenation -- Correction of blepharoplasty complications, management of the elevated upper eylid during blepharoplasty -- Atypical granulomas and infection after blepharoplasty -- Autogenous allogeneic and alloplastic lower lid spacers after blepharoplasty
  • pt. 1. GENERAL ASPECTS OF MIDKINE -- General Information on Midkine / Takashi Muramatsu -- The Role of Midkine in Neural Development and Patterning / Sheng Yao and Christoph Winkler -- Midkine: A Player in Innate Immunity / Sara L. Nordin and Arne Egesten -- Midkine/P63 Axis in Regulation of Epithelial-Mesenchymal Transition / Yiping Huang and Edward A. Ratovitski -- Immunochemical Methods for the Detection of Midkine in Samples of Human Origin / Stefan Sommerschuh, Michael Kirchner and Nicole Gliese -- Circulating Midkine in Malignant, Inflammatory, and Infectious Diseases: A Systematic Review / Malgorzata Krzystek-Korpacka and Malgorzata Matusiewicz -- pt. 2. MIDKINE AND INFLAMMATION -- Midkine in Inflammation and Inflammatory Diseases / Nuray Yazıhan, Mehtap Kacar Kocak and Ethem Akcıl -- Rheumatoid Arthritis and Midkine / Hisako Muramatsu, Kiyoko Maruyama and Naoki Ishiguro -- pt. 3. MIDKINE AND THE CARDIOVASCULAR SYSTEM -- Midkine and Heart Failure / Mitsuru Horiba and Kenji Kadomatsu -- Vascular Restenosis and Midkine / Kenji Kadomatsu -- The Potential of MK Through the Renin-Angiotensin System / Tomoki Kosugi and Kenji Kadomatsu -- pt. 4. MIDKINE AND THE NERVOUS SYSTEM -- Midkine and Multiple Sclerosis / Hideyuki Takeuchi -- Midkine Gene Transfer in Brain Infarction / Hiroaki Ooboshi, Eiichi Ishikawa, Junichi Takada, Takashi Shichita and Yasuhiro Kumai -- Midkine in Psychiatric and Neurodegenerative Diseases / Eiji Shimizu and Daisuke Matsuzawa -- pt. 5. MIDKINE AND THE UROGENITAL SYSTEM, REPRODUCTION AND AGING -- Role of Midkine in Nephrogenesis and Kidney Disease / Waichi Sato and Kenji Kadomatsu -- Midkine, a Factor Promoting Cytoplasmic Maturation of Oocytes / Masayasu Yamada, Yuuki Isaji and Shuntaro Ikeda -- Endometriosis May Be Promoted by Midkine: Possible Involvement of Ovarian Follicles / Yutaka Osuga, Yasushi Hirota, Kaori Koga, Osamu Yoshino and Tetsuya Hirata -- Stem Cells and Midkine / Hisako Muramatsu, Peng Zou and Takashi Muramatsu -- Midkine in Skeletal Physiology / Astrid Liedert, Thorsten Schinke, Anita Ignatius and Michael Amling -- pt. 6. MIDKINE AND CANCER -- Midkine and Chemoresistance in Cancers / Yoshifumi Takei and Kenji Kadomatsu -- A Gene Medicine with the Midkine-mediated Transcriptional Regulation as New Cancer Therapeutics / Masatoshi Tagawa, Kiyoko Kawamura, Ling Yu, Yuji Tada and Kenzo Hiroshima, et al. -- Midkine as a Tumor-Shared Antigen / Jerome Kerzerho, Florence Anne Castelli and Bernard Maillère -- Midkine in Prostate Cancer / Zongbing You -- Midkine Is a Potential Therapeutic Target of Hepatocellular Carcinoma / Li Cheng Dai, Xing Yao and Jing Zhong -- Midkine in Glioblastoma with the Modulator Role Switching Autophagy to Cell Death or Cell Survival / Mine Ergüven and Ayhan Bilir -- Colon Cancer and Midkine / Özgür Kemik, Ahu Sarbay Kemik and A. Cumhur Dülger -- Osteosarcoma and Midkine / Tadashi Kaname, Kumiko Yanagi and Hiroki Maehara.
  • The role of milk during the life cycle - a global view
  • 1. Milk, nutrition and human health / A. J. Rugg-Gunn and P. E. Petersen -- 2. Clinical studies / J. Bánóczy and A.J. Rugg-Gunn -- 3. Basic science studies / W. M. Edgar -- 4. The addition of fluoride to milk / A. E. Villa -- 5. The Implementation of community based programmes / S. M. Woodward -- 6. Evaluating fluoride exposure in milk fluoridation programmes / A. E. Villa -- 7. Programme evaluation / P. E. Petersen and A. J. Rugg-Gunn -- 8. Conclusions
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  • Using a clinically relevant, systems-based approach, this medical textbook accessibly explains the microbiology of the agents that cause diseases and the diseases that affect individual organ systems. With lavish illustrations and straightforward, accessible explanations, Richard Goering makes this complex subject simple to understand and remember. 150 multiple choice review questions. "Pathogen Parade" and many other features to enhance learning and retention. Enhance your learning and absorb complex information in an interactive, dynamic way. Deepen your understanding of epidemiology and the important role it plays in providing evidence-based identification of key risk factors for disease and targets for preventive medicine. A completely re-written chapter on this topic keeps abreast of the very latest findings.
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    In the culminating volume of her nationalism trilogy, Greenfeld argues that we have overlooked the connection between egalitarian society and mental illness. Modern nationalism rests on principles of popular sovereignty, equality, and secularism. Citizens of the twenty-first century enjoy unprecedented freedom to become the authors of their personal destinies. Empowering as this is, it also places them under enormous psychic strain. They must constantly appraise their identities, manage their desires, and calibrate their place within society. For vulnerable individuals, this pressure is too much. Training her analytic eye on extensive case histories in manic depression and schizophrenia, Greenfeld contends that these illnesses are dysfunctions of selfhood caused by society's overburdening demands for self-realization. In her rigorous diagnosis, madness is a culturally constituted malady.
  • Mindfulness in Therapy -- A Mindful Re-visioning of Couple and Family Therapy Practice -- Mindfulness Research Foundations -- Therapeutic Presence and Mindfulness -- Mindfulness-Informed Case Conceptualization and Treatment Planning -- Teaching Mindfulness Practice in Therapy -- Foundational Mindfulness- and Acceptance- Informed Interventions and Practices -- Mindfulness and Acceptance Interventions for Couples and Families -- Training and Supervision -- Therapist Self-Care and Style of Life.
  • Mineral components in food: analytical implications / M. Biziuk, J. Kuczynska -- Speciation of mineral components in food: analytical implications / A. Polatajko, J. Szpunar -- Criteria of evaluation of food trace analysis data / B. Szteke -- Chemometric techniques in analytical evaluation of food / P. Szefer -- Functional role of some minerals in foods / M. Nabrzyski -- Mineral components and their species in foods of animal origin and honeys / P. Szefer, M. Grembecka -- Mineral components and their species in plant foods, beverages, luxury food, spices and dietary food / P. Szefer, M. Grembecka -- Trace elements in wines / S. Galani-Nikolakaki, N. Kallithrakas-Kontos -- Heavy metals in food packagings / M. E. Conti -- Pollutants in food: metals and metalloids / C. Reilly -- Pollutants in food: radionuclides / Z. Oul-Dada -- Assessment of exposure to chemical pollutants in food and water / P.J. Peterson -- Metal contamination of dietary supplements / M.J. Slotnick, J.O. Nriagu.
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    v. 1. Principles, processes, and systems. 2 pts. -- v. 2. The elements. 2 pts -- v. 3. Calcium physiology.
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  • In recent years, mini-invasive surgery has become increasingly important for reducing the risk of infection and minimizing blood loss and volume of implants. Hip surgery requires small incisions, which make the use of the appropriate equipment and an extensive knowledge of the anatomy of the region essential. Mini-invasive surgery requires the surgeon to consider the indications for surgery for each patient he treats and to know the exact loco-regional anatomy for that patient. Methods must be very precise and warrant visual explanations to help teach young surgeons.
  • Part 1. Introduction -- Minimal Residual Disease and Circulating Tumor Cells in Breast Cancer: Open Questions for Research / Michail Ignatiadis, Christos Sotiriou and Klaus Pantel -- Part 2. Minimal residual disease and breast cancer metastasis -- Self-Seeding in Cancer / Elizabeth Comen and Larry Norton -- Microenvironments Dictating Tumor Cell Dormancy / Paloma Bragado, Maria Soledad Sosa, Patricia Keely, John Condeelis and Julio A. Aguirre-Ghiso -- Part 3. Technologies for circulating tumor cell (CTC) and disseminated tumor cell (DTC) detection and characterization -- Immunomagnetic Separation Technologies / Astrid E. L. M. Hoeppener, Joost F. Swennenhuis and Leon W. M. M. Terstappen -- Microfluidic Technologies / Ali Asgar. S. Bhagat and Chwee Teck Lim -- EPISPOT Assay: Detection of Viable DTCs/CTCs in Solid Tumor Patients / Catherine Alix-Panabières -- Advances in Optical Technologies for Rare Cell Detection and Characterization / Lou Dietz and Richard Bruce -- Size-Based Enrichment Technologies for CTC Detection and Characterization / Anthony Williams, Marija Balic, Ram Datar and Richard Cote -- Emerging Technologies for CTC Detection Based on Depletion of Normal Cells / Maryam Lustberg, Kris R. Jatana, Maciej Zborowski and Jeffrey J. Chalmers -- Molecular Assays for the Detection and Characterization of CTCs / Evi S. Lianidou and Athina Markou -- Multiplex Molecular Analysis of CTCs / Anieta M. Sieuwerts and Stefanie S. Jeffrey -- Part 4. Other blood-based biomarkers / Circulating DNA and Next-Generation Sequencing -- Susanna Cooke and Peter Campbell -- Circulating MicroRNAs as Noninvasive Biomarkers in Breast Cancer / Maria Angelica Cortez, James William Welsh and George Adrian Calin -- Circulating Endothelial Cells and Circulating Endothelial Progenitors / Patrizia Mancuso, Angelica Calleri and Francesco Bertolini -- Part 5. Disseminated tumor cells (DTCs) and circulating tumor cells (CTCs) in breast cancer clinical research and practice -- DTCs in Breast Cancer: Clinical Research and Practice / W. Janni, Brigitte Rack, N. Kasprowicz, C. Scholz and P. Hepp -- CTCs in Primary Breast Cancer (I) / Brigitte Rack, Ulrich Andergassen, Wolfgang Janni and Julia Neugebauer -- CTCs in Primary Breast Cancer (II) / E. Saloustros and D. Mavroudis -- CTCs in Metastatic Breast Cancer / Antonio Giordano and Massimo Cristofanilli -- HER2-Positive DTCs/CTCs in Breast Cancer / Andreas D. Hartkopf, Malgorzata Banys and Tanja Fehm -- DTCs/CTCs in Breast Cancer: Five Decades Later / Susan Alsamarai, Maysa M. Abu-Khalaf and Lyndsay N. Harris -- Part 6. Drug and circulating tumor cell co-development -- Challenges in Drug and Biomarker Co-Development / Sheila E. Taube and Tracy Lively -- Challenges and Opportunities in the Use of CTCs for Companion Diagnostic Development / Elizabeth A. Punnoose and Mark R. Lackner.
  • "Minimally Invasive and Robotic Thyroid and Parathyroid Surgery is the first textbook which includes a comprehensive review of both minimally invasive and robotic thyroid and parathyroid techniques. Over the last several years there has been a rapid expansion in the number of different surgical approaches available to patients undergoing thyroid and parathyroid surgery. This book consolidates these in one source and focuses on both the philosophy and techniques of these procedures. For thyroid surgery, the text covers the full range of minimally invasive procedures and several of the most widely adopted remote access techniques. Several related procedures are also discussed, including minimally invasive approaches to central and lateral neck dissection. For parathyroid surgery, several minimally invasive techniques are covered, including radioguided surgery. Written by experts in the field of thyroid and parathyroid surgery, Minimally Invasive and Robotic Thyroid and Parathyroid Surgery serves as a critical resource for both experienced and less experience surgeons, fellows, residents, and students interested in understanding the breadth of this field or learning the specific steps of a particular technique."--Publisher's website.
  • Part I. Preoperative -- 1. Perioperative Assessment / Charlotte Kvasnovsky and Andrea Chao Bafford -- 2. Patient Positioning, Instrumentation, and Trocar Placement / Mehraneh Dorna Jafari, Michael J. Stamos, and Steven Mills -- 3. Surgical Anatomy / Todd D. Francone and Ron G. Landmann -- Part II. Procedures -- 4. Right Colectomy: Straight Laparoscopic / Steven Robert Hunt -- 5. Right Colectomy: Hand-Assist / Kirk A. Ludwig and Timothy Ridolfi -- 6. Laparoscopic Sigmoidectomy/Left Colectomy / Toyooki Sonoda -- 7. Hand-Assisted Left Colectomy / Steven Lee-Kong and Daniel L. Feingold -- 8. Total Abdominal Colectomy: Straight Laparoscopic Approach / Amanda V. Hayman and Eric J. Dozois -- 9. Total Abdominal Colectomy: Hand- Assisted Approach / Kiyokazu Nakajima, Tsunekazu Mizushima, and Riichiro Nezu -- 10. Operative Details of Laparoscopic Rectal Resection for Cancer / Martin R. Weiser -- 11. Laparoscopic Hand-Assisted Low Anterior Resection / Govind Nandakumar and Sang W. Lee -- 12. Laparoscopic Abdominoperineal Resection / Jennifer S. Davids and Justin A. Maykel -- 13. Laparoscopic Proctocolectomy / David A. Etzioni and Tonia M. Young-Fadok -- 14. Laparoscopic Rectopexy / Mia DeBarros and Scott R. Steele -- 15. Minimally Invasive Approach for Stoma Creation / Seth I. Felder, Zuri Murrell, and Phillip Fleshner -- 16 Laparoscopic Stoma Reversal / Emre Gorgun -- 17. Laparoscopic Parastomal Hernia Repair / Joshua A. Tyler and Matthew G. Mutch -- Part III. Technical Challenges and Tips -- 18. Overcoming Technical Challenges: The Abdomen / Eric K. Johnson -- 19. Overcoming Technical Challenges: The Pelvis / M. Shane McNevin -- 20. Overcoming Technical Challenges: Reoperative Surgery / Brian R. Englum, M. Benjamin Hopkins, and John Migaly -- 21. Overcoming Technical Challenges: Prevention and Managing Complications / Bradley R. Davis -- Part IV. New Horizons -- 22. Single-Incision Laparoscopic Approaches to Colorectal Disease / Virgilio George -- 23. Natural Orifice Surgery (NOTES) / Mark H. Whiteford -- 24. Robotic Surgery /Mehraneh Dorna Jafari, David E. Rivadeneira, and Alessio Pigazzi -- 25. Transanal Minimally Invasive Surgery (TAMIS): Operative Technique, Pitfalls, and Tips / Francisco Quinteros, Kumaran Thiruppathy, and Matthew R. Albert -- 26. Combined Endo-Laparoscopic Surgery (CELS) / Kelly A. Garrett and Sang W. Lee -- Part V. Special Situations -- 27. Emergent Laparoscopic Colorectal Surgery / Rodrigo Pedraza and Eric M. Haas -- 28. Laparoscopy in the Elderly Patient / Joshua I. S. Bleier and Brian R. Kann -- 29. Laparoscopic Colectomy in the Obese Patient / Arida Siripong and H. David Vargas -- 30. Minimally Invasive Surgery in Crohn's Disease Patients / Chang Sik Yu -- 31. Minimally Invasive Surgery in Ulcerative Colitis Patients / Marco E. Allaix and Alessandro Fichera -- 32. Minimally Invasive Approaches to Colon and Rectal Diseases: Technique and Best Practices--Pediatrics / Eric J. Krebill and Daniel J. Robertson -- 33. Laparoscopy in Pregnant Patients / Melissa M. Alvarez-Downing and David J. Maron -- 34. Economics of Laparoscopic Colectomy / Anthony J. Senagore -- 35. Outcomes of Laparoscopic Surgery / Jennifer Leahy and Rocco Ricciardi -- Part VI. Conclusions -- 36. Future Directions in Minimally Invasive Surgery / Howard M. Ross and Matthew Miller Philp.
  • The second edition of Minimally Invasive Bariatric Surgery provides a comprehensive, state-of-the art review of this field, and it serves as a valuable resource for clinicians, surgeons and researchers with an interest in minimally invasive bariatric surgery. Additionally, the second edition includes new features that will benefit the resident, fellow, or bariatric surgeon new to the field. Specifically, each evidence-based chapter (i.e. outcomes, complications, epidemiology, etc) concludes with three or four exam questions that emphasize the salient points of the chapter and provide fellowship programs a valuable training tool and resource for their academic curriculum. These questions are either single-answer multiple choice or true/false format and the correct response with a brief explanation follows. As more emphasis is placed on completing a comprehensive curriculum and obtaining certification for bariatric training, this aspect of the book is unique and provides added value to the text. The new edition also incorporates many new or updated medical illustrations to enhance the technique chapters and provide more uniformity for the artwork throughout the book. Each of the major procedures include surgical technique, outcomes, and management of complications in separate chapters to provide an easy reference for the busy clinician preparing for a case or presentation. Another unique feature of the text is a link to video files hosted online for the relevant chapters. This video library will be of great value to the user. As the number of fellowships in laparoscopic bariatric surgery continues to increase, this updated text will provide a valuable resource for general and bariatric surgeons, laparoscopic surgeons, fellows, residents, medical students, obesity researchers, and industry representatives involved in this field. Minimally Invasive Bariatric Surgery is a valuable resource for Medical students, surgical oncology fellows, general surgeons, and educators.
  • As minimal access approaches to cancer diagnosis, staging, and therapy become more widely used, it is vital for general surgeons, along with laparoscopists, surgical oncologists and medical oncologists, to stay up to date. The editors, a team consisting of a renowned surgical oncologist and a laparoscopic specialist, aim to provide a resource for the practicing general surgeon using basic minimally invasive techniques. The book discusses diagnosis including biopsy with microinstrumentation, staging, and palliative and curative resection. Specific tumor sites are addressed, including esophagus, stomach, spleen, small bowel, pancreato-biliary, hepatic resection, and colo-rectal resection. Minimally invasive approaches to the thoracic and retroperitoneal areas are included. The book provides a thorough overview of basic cancer biology, instrumentation, and ultrasound. Additionally, Greene and Heniford explore controversial issues such as port-site recurrence and the effect of pneumoperitoneum on the spread of cancer cells in the abdomen. Many photographs and line drawings, including 16 in full color, illustrate the principles discussed in the text. A must-have for every practicing general surgeon, laparoscopic fellow, and general surgery resident.
  • Botox® cosmetic / Alan Matarasso, David Shafer -- Chemical peels / Richard H. Bensimon -- Radiofrequency ablation for the reduction of glabellar frowning / James Newman -- Dermabrasion . Farzad R. Nahai -- Wire dissection to correct facial rhytids / Miles H. Graivier -- Use of barbed sutures in the face / Malcolm D. Paul -- Facial rejuvenation with structural fat grafting / Alesia P. Saboeiro, Sydney R. Coleman / Necklift vs neck rejuvenation / Patrick K. Sullivan, Erik A. Hoy -- Short-scar facelift / Alexis M. Verpaele, Patrick L. Tonnard -- Endoscopic brow lift / Renato Saltz, Mark A. Codner -- Treatment of the superficial musculo-aponeurotic system during minimally invasive facial rejuvenation / Salvatore J. Pacella, Farzad Nahai, Mark A. Codner -- Limited Incision midface lift / Oscar M. Ramirez. DVD Contents: Clinical uses of Botox® / Alan Matarasso, David M. Shafer -- Trichloracetic acid chemical peel / Mark A. Codner -- Croton oil peel / Richard H. Bensimon -- Dermabrasion / Farzad R. Nahai -- Wire dissection to correct facial rhytids / Miles H. Graivier -- Submental dissection /Farzad R. Nahai -- Short scar facelift / Foad Nahai -- Endoscopic browlift / Mark A. Codner -- Limited incision midface lift / Oscar M. Ramirez.
  • Minimally Invasive Forefoot Surgery in Clinical Practice describes a number of the better established and accepted minimally invasive surgical correction techniques for forefoot problems, and is aimed at junior and general orthopedic surgeons who require a useful easy reference for these procedures.The concise written text is complemented by a generous assortment of useful photos, diagrams, and imaging studies.
  • This book provides detailed, comprehensive and illustrative content to the surgical community in the areas of foregut oncologic surgery. The text contains an in-depth review of all surgical aspects of oncologic diseases involving the stomach and esophagus. The main focus is on the minimally invasive techniques including potential complications and their management. The text also includes an online link to the videos for all minimally invasive foregut surgical procedures, including animation content which provide a more comprehensive learning experience. Minimally Invasive Foregut Surgery for Malignancy: Principles and Practice is structured in a way that makes it useful at every level of training and will be of great utility to practicing surgeons, fellows in surgical subspecialty training and surgical residents.
  • Part I. -- Techniques -- Endoscopic techniques, equipment, and optics / Liliana C. Goumnerova -- MR imaging of the central nervous system / Liangge Hsu -- Proton MR spectroscopy / Amir A. Zamani -- Functional brain mapping options for minimally invasive neurosurgery / Alexandra J. Golby and Kathleen A. McConnell -- Image guidance in minimally invasive neurosurgery / Richard D. Bucholz and Lee McDurmont -- Intraopertive imaging using the siemans and tesla MR systems / Christopher Nimsky and Rudolf Fahlbusch -- Endovascular treatment of intracranial aneurysms / Christos Gkogkas, John Baker, Alexander M. Norbash, and Kai U. Frerichs -- Stent angioplasty for the treatment of intracranial cerebrovascular disease / Adel M. Malek and Clemens M. Schirmer -- The role of embolic agents in the endovascular treatment of intracranial arteriovenous malformations and tumors / Ricardo A. Hanel, Bernard R. Bendok, Jay U. Howington, Elad I. Levy, Lee R. Guterman, and L. Nelson Hopkins -- Radiofrequency lesioning / Michael Petr and John M. Tew, Jr. -- Radiosurgery:tTechniques and applications / William A. Friedman -- MRI-guided thermal therapy for brain tumors / Ferenc A. Jolesz and Ion-Florin Talos -- Gene-based and viral-based therapies / Manish Aghi and E. Antonio Chiocca -- Local delivery methods into the central nervous system / Timothy W. Vogel and Jeffrey N. Bruce -- Part II Specialties -- Minimally invasive pediatric neurosurgery / Michael Weaver and Mark R. Proctor -- Minimally invasive techniques in vascular neurosurgery / Prithvi Narayan and Daniel L. Barrow -- Minimally invasive treatment for brain tumors / Dennis S. Oh and Peter M. Black -- New directions in spinal surgery / Ian F. Dunn and Marc E. Eichler -- Endoscopic techniques in the management of carpal tunnel syndrome / David F. Jimenez -- Minimally invasive procedures in traumatic brain injury / Edward Ahn, William C. Chiu, Max Wintermark, Bizhan Aarabi, and Howard Eisenberg
  • Minimally invasive oculoplastic surgery / Michèle Beaconsfield and Richard Collin -- Minimally invasive conjunctival surgery / Shigeru Kinoshita ... [et al.] -- Minimally invasive lacrimal surgery / Rainer K. Weber -- Minimally invasive corneal surgery / Heather M. Skeens and Edward J. Holland -- Minimally invasive refractive surgery / Jorge L. Alio, Mohamad Rosman, and Samuel Arba Mosquera -- Minimally invasive strabismus surgery / Daniel S. Mojon -- Minimally invasive iris surgery / Roger F. Steinert -- Minimally invasive glaucoma surgery / Elie Dahan ... [et al.] -- Minimally invasive cataract surgery / I. Howard Fine, Richard S. Hoffman, and Mark Packer -- Minimally invasive vitreoretinal surgery / Loh-Shan Leung, Woo Ho Nam, and Stanley Chang.
  • Daniel H. Kim, MD, FACS, Kyung Hoon Kim, MD, and Yong Chul Kim, MD, helps you apply methods of spinal pain relief that involve less risk and shorter recovery times. Focusing on the broad appeal of this goal for you and your patients, this volume will help surgeons and specialists in various areas of pain management provide less invasive alternatives and faster recovery procedures for those suffering with spinal injuries. Step-by-step techniques are well-illustrated in the book and demonstrated extensively on DVD. Reduce the risk associated with invasive spinal procedures by