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  • Percutaneous mitral balloon valvuloplasty for patients with rheumatic mitral stenosis : immediate and long-term followup results / Igor F. Palacios -- Balloon aortic and pulmonic valvuloplasty / Ted E. Feldman, Timothy A. Sanborn, and William W. O'Neill -- Pathophysiology and percutaneous coronary sinus repair of mitral regurgitation / Nicholas Valettas, Joseph H. Gorman III, and Robert C. Gorman -- Percutaneous coronary sinus approach to the treatment of mitral regurgitation / Fumiaki Ikeno ... [et al.] -- Percutaneous mitral valve repair with the edge-to-edge technique / Frederick G. St. Goar ... [et al.] -- Percutaneous valve insertion for the treatment of calcific aortic valve stenosis / Alain Cribier ... [et al.] -- Patent foramen ovale : neurological considerations / Steven R. Messa, Scott E. Kasner, and Anthony Furlan -- CardioSEAL, cardioSEAL-STARFlex, and PFO-star closure of PFO / Michael J. Landzberg -- Percutaneous closure of patent foramen ovale with the amplatzer PFO occluder : European experience / Andreas Wahl, Stephan Windecker, and Bernhard Meier -- Transcatheter closure of atrial septal defects using the amplatzer devices / Hitendra Patel ... [et al.] -- An overview of device closure of ventricular septal defects using the amplatzer devices / Ralf Holzer, Qi-Ling Cao, and Ziyad M. Hijazi -- Left atrial appendage occlusion / Mark Reisman -- Devices for myocardial preservation / Simon R. Dixon and William W. O'Neill -- Percutaneous mechanical assist devices / Suresh R. Mulukutla and Howard A. Cohen -- Alcohol septal ablation for hypertrophic obstructive cardiomyopathy / Haran Burri and Ulrich Sigwart -- Therapeutic angiogenesis and myocardial regeneration / G. Chad Hughes and Brian H. Annex -- Renal and iliac intervention / Michael T. Caulfield, Dharsh Fernando, and Kenneth Rosenfield -- Percutaneous carotid artery stenting / Cameron Haery and Jay S. Yadav -- Aortic stent grafting : percutaneous and surgical approaches / Omaida C. Velazquez, Edward Woo, and Ronald M. Fairman -- Interventional echocardiography / Frank E. Silvestry -- 3D angiography / Nathan E. Green ... [et al.] -- Interventional cardiovascular MRI : current status and future directions / Milind Y. Desai, Albert C. Lardo, and Joao A.C. Lima.
  • Systems for Interventional MRI / Stephen G. Hushek -- Pulse Sequences for Interventional MRI / Walter F. Block and Benjamin P. Grabow -- MR-Compatible Instruments for Interventional MRI / Harald H. Quick -- Navigation Techniques for MRI-Guided Interventions / Harald Busse, Thomas Kahn and Michael Moche -- Safety Considerations in Interventional MRI / Harald Kugel -- Anesthetic Concerns in the MR Environment / Ramon Martin -- MRI Guidance of Minimally Invasive Cranial Applications / Chip Truwit, Alastair J. Martin and Walter A. Hall -- MRI Guidance of Intracranial Tumor Resections / Daniela Kuhnt, Miriam H. A. Bauer, Oliver Ganslandt and Christopher Nimsky -- MRI Guidance of Musculoskeletal Interventions / Roberto Blanco Sequeiros, Jan Fritz and John A. Carrino -- High-Field Open MRI-Guided Interventions / Ulf K.-M. Teichgräber, Florian Streitparth and Felix V. Güttler -- MR-Guided Breast Interventions / Karin Hellerhoff and Clemens Cyran -- MRI Guidance of Vascular Applications / Gabriele A. Krombach -- Magnetic Resonance-Guided Embolization of Low-Flow Vascular Malformations / Sumera Ali, Clifford R. Weiss, Daniel P. Hsu and Jonathan S. Lewin -- MRI Guidance of Cardiac Applications / Tarique Hussain, Israel Valverde, Reza Razavi and Tobias Schaeffter -- MR-Guided Prostate Biopsy / Derya Yakar and Jurgen J. Fütterer -- MRI-Guided Therapeutic Procedures in Recurrent Prostate Cancer / David A. Woodrum, Akira Kawashima, Krzysztof R. Gorny and Lance A. Mynderse -- MRI-Guided Thermal Ablation Techniques / R. Jason Stafford and Kamran Ahrar -- MR Thermometry / Viola Rieke -- MRI-Guided Laser Ablation in the Liver / Christian Rosenberg and Norbert Hosten -- MRI-Guided RF Ablation in the Liver / Hansjörg Rempp, Rüdiger Hoffmann, Stephan Clasen and Philippe L. Pereira -- MRI-Guided RF Ablation in the Kidney / Sherif G. Nour and Jonathan S. Lewin -- MR-Guided Focused Ultrasound Treatment of Uterine Fibroids / Wladyslaw M. Gedroyc -- MRI-Guided High-Intensity Focused Ultrasound Sonication of Liver and Kidney / Baudouin Denis de Senneville, Mario Ries, Lambertus W. Bartels and Chrit T. W. Moonen -- MR-Guided Focused Ultrasound of the Brain / Rivka R. Colen and Ferenc A. Jolesz -- MRI-Guided Brachytherapy in the Liver / Uta Wonneberger, Frank Fischbach, Jürgen Bunke, Kerstin Jungnickel and Jens Ricke -- MRI-Guided Microwave Ablation / Shigehiro Morikawa, Shigeyuki Naka, Hiroyuki Murayama, Yoshimasa Kurumi and Tohru Tani, et al. -- MRI-Guided Stem Cell Therapy / Tina Ehtiati and Dara L. Kraitchman -- MR-Guided Delivery and Tracking of Cellular Therapeutics / Paul A. DiCamillo and Clifford R. Weiss -- Hybrid MRI Systems and Applications / Wesley D. Gilson and Frank Wacker -- Simultaneous Ultrasound Imaging and MRI Acquisition / Lorena Petrusca, Magalie Viallon, Sylvain Terraz, Valeria de Luca and Zarko Celicanin, et al. -- Simultaneous Endoscopy and MRI Acquisition / Hasnine A. Haque, Shigehiro Morikawa, Shigeyuki Naka, Yoshimasa Kurumi and Hiroyuki Murayama, et al.
  • Headache Classifications and Medically Resistant Headaches -- Algorithms for the Diagnosis and Management of Head and Face Pain -- Peripheral Nerve Block for the Management of Headache and Face Pain -- Occipital Nerve Blocks -- Occipital Neuralgia: The Role of Ultrasound in the Diagnosis and Treatment -- Glossopharyngeal Nerve Block -- Sphenopalatine Ganglion Block and Radiofrequency Ablation -- Trigeminal (Gasserian) Ganglion, Maxillary Nerve, and Mandibular Nerve Blocks -- Interventional Treatment for Trigeminal Neuralgia: Radiofrequency and Neuromodulation -- Practical Approach to Cervicogenic Headache -- Atlantoaxial Joint: Atlantoaxial Joint Injection and Radiofrequency Ablation -- Third Occipital Nerve Block and Radiofrequency Ablation -- Cervical Facet Syndrome: Cervical Medial Branch Block and Radiofrequency Ablation -- Intravenous Therapies for Intractable Headache -- Onabotulinum Toxin Injection and Headaches -- Epidural Blood Patch -- Occipital Nerve Stimulation for Head Pain: Surgical Leads -- Occipital Nerve Stimulation for Head Pain: Percutaneous Leads -- Sphenopalatine Ganglion Stimulation -- Deep Brain and Motor Cortex Stimulation for Head and Face Pain.
  • 1. Pre-operative Evaluation -- History -- 2. Pre-operative Evaluation -- Physical Examination -- 3. Admission After Intervention -- When and Why -- 4. Communicating Effectively for Interventional Nephrologists -- 5. Anticoagulants and Thrombolytics -- 6. Non-invasive Screening and Testing for PAD in CKD patients -- 7. Overview of PAD Treatment in the CKD Population: Indications, Medical Strategies, and Endovascular Techniques -- 8. Unconventional Venous Access: Percutaneous Translumbar and Transhepatic Venous Access for Hemodialysis -- 9. Approach to a Non-Functioning Catheter -- 10. Approach to the Infected Catheter -- 11. Approach to a Patient Referred for Vascular Mapping -- 12. Approach to Arteriovenous Access -- 13. Approach to a Patient with Non-maturing AV Fistula -- 14. Approach to an Arteriovenous Access with Hyperpulsatile Pulse -- 15. Approach to an Arteriovenous Access with a Faint Thrill -- 16. Approach to an Arteriovenous Access with No Thrill, Bruit, or Pulse -- 17. Approach to Patient with Arteriovenous Access Presenting with Hand Pain -- 18. Central Vein Stenosis -- 19. Approach to a Patient with Pseudoaneurysm -- 20. Approach to Chest Pain During Dialysis -- 21. Approach to Cyanotic Digits and Hand Paresis -- 22. Approach to an Abnormal Surveillance Measurement -- 23. Arterial Stenosis Affecting Arteriovenous Fistulae and Grafts in Hemodialysis Patients: Approach to Diagnosis and Management -- 24. Approach to the Patient with Suspected Renal Artery Stenosis -- 25. Vascular Injury During Interventions -- 26. Pulmonary Embolism Associated with Dialysis Access Procedure -- 27. Stent Migration -- 28. Foreign Body Retrieval -- 29. Contrast and Medication Allergic Reactions -- 30. The Management of Serious Adverse Events Associated with Interventional Procedures -- 31. Preoperative Evaluation of a Patient for Peritoneal Dialysis Catheter -- Operative Considerations for Peritoneal Dialysis Catheter -- Approach to a Patient with Visceral Perforation.
  • Accurate interpretation of indications for treatment is the cornerstone of success in medicine. This book carefully examines the relation between clinical features, diagnosis, and choice of minimally invasive technique for a range of spine pathologies. It explains how selection of technique is intimately related to clinical and diagnostic aspects and how recognition of this relation forms the foundation for an optimal outcome. In addition to examining the various minimally invasive options, including the latest techniques, careful attention is paid to the role of medical treatment in avoiding recurrence after initial therapy. Nerve blocks, epidural injections, and intradiscal procedures are among the many options available in the armamentarium of the interventionalist, and advice is given on their use in different contexts.
  • The objective ofthe Techniquesin Interventional Radiology series is to provide easily accessible technique specific information on interventional radiology procedures, suitable for reference in the IR room or as a carry-around guide. Each volume has an EU and US editor so that the perspectives presented are balanced across these two major centres of interventional radiology. Each volume has a consistent template for easy and quick reference, with step-by-step bullet points, key point summaries at the end of each chapter and illustrations/line drawings as a visual aid. Interventional Neuroradiology will bring to the fore the collective wisdom of specialist interventional neuroradiologists, for their own reference and more crucially for the reference of trainees in interventional neuroradiology. This book will appeal to thosealready practisinginterventional neuroradiology and those taking fellowships in the speciality from neurology, neurosurgery or neuroradiology.
  • Interventional Oncology is a fast-growing new field, as well as an emerging specialty. Many minimally-invasive, imaging-guided procedures seem set to replace more traditional open surgical techniques of treating solid tumors in a variety of organs. The aim of this book is to describe new interventional radiological methods in a succinct and practical form. Diagnostic radiological considerations relevant to the selection and follow-up of patients are also covered. The book begins with an overview of the basic principles of current interventional techniques, including thermal ablation, high intensity focused ultrasound, and embolization. Later chapters focus on tumors of the liver, kidney, lung, and bone, placing new interventional techniques in context by referring to the surgical and oncologic methods of treating the same conditions. With an emphasis on best practices, Interventional Oncology: A Practical Guide for the Interventional Radiologist will serve as a definitive guide to practicing physicians involved in this rapidly evolving field.
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  • Apply the latest percutaneous techniques with the practical, highly illustrated Interventional Procedures for Structural Heart Disease. This brand-new medical reference book presents full-color images, numerous tables, and invaluable clinical pearls to help you utilize today's hottest techniques and technologies for each disease, so you can offer your patients the most desirable outcomes possible. Master today's hottest percutaneous procedures for structural heart disease as perfected by experts from around the world, including transcatheter aortic valve replacement (TAVR), percutaneous paravalvular leak closure, transcatheter mitral valve interventions, a wide variety of adult congenital cardiovascular defect interventions, and more.Grasp the specific knowledge you will need for success in a variety of clinical scenarios, as well as the patient selection criteria for each invasive procedure.Make informed, evidence-based decisions with the latest clinical trial results and evidence integrated into each chapter.Visualize the newest techniques and technologies more clearly through a full-color design featuring illustrations, tables, clinical pearls, complications, and current evidence boxes.
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    New bronchoscopic instrumentation : a review and update in rigid bronchoscopy / Yarmus and Feller-Kopman -- Laser bronchoscoopy, electrosurgery, APC, and microdebrider / Bolliger -- Update on cryotherapy, brachytherapy, and photodynamic therapy / Lahm, Sheski -- Airway stents / Lee, Kupeli, Mehta -- High-resolution brochoscopy : bringing these modalities into focus / Riker -- Endoscopic staging of lung cancer / Yasufuku -- Medical thoracoscopy / Villanueva, Gonzalez -- Tunneled pleural catheters / MacEachern, Stather, Tremblay -- Bronchoscopic lung volume reduction in COPD / Diaz-Guzman, Mehta -- Bronchial thermoplasty / Mayse, Castro -- Sedation, analgesia and anesthesia for airway procedures / Nystrom, Mathur -- Advanced bronchoscopic techniques for diagnosis of peripheral pulmonary lesions / Lee, Ost -- Bronchoscopic treatment of peripheral lung nodules / Puchalskim Sterman -- Percutaneous dilational tracheostomy / Lamb -- Training in interventional pulmonology / Wang, Silvestri -- Role of bronchoscopy in lung transplant patients / von Garnier, Chhajed.
  • Interventional radiology 2010
    Thieme Book
  • This book is a practical resource for the current applications of interventional radiology in the care of female patients. Divided into seven main sections, the book opens with an introduction to the role of interventional radiology in women's health, discussing such topics as specific concerns relevant to the female patient and safety considerations related to the provision of care. The sections that follow address common clinical problems and conditions unique to women, including uterine fibroids, infertility, pelvic pain, osteoporosis, and varicose veins. A final section describes interventional procedures for treating breast cancer and offers key recommendations for further practice development.
  • General principles of biopsy and drainage -- Liver biopsy -- Chest biopsy -- Mediastinal biopsy -- Bone biopsy -- Adrenal biopsy -- Renal biopsy -- Pancreatic biopsy -- Lymph node biopsy -- Splenic biopsy -- Thyroid biopsy -- Prostate biopsy -- Drainage of abdominal fluid collections -- Drainage of pelvic fluid collections -- Drainage of intrathoracic fluid collections -- Liver cyst/abscess drainage -- Drainage of pancreatic abscess and fluid collections -- Percutaneous biliary drainage and stenting -- Percutaneous cholecystostomy and cholecystolithotomy -- Percutaneous nephrostomy and antegrade ureteric stenting -- Fluoroscopy-guided percutaneous renal access for treatment of stone disease -- Percutaneous gastrostomy and gastrojejunostomy.
  • The Techniques in Interventional Radiology series of handbooks describes in detail the various interventional radiology procedures and therapies that are in current practice.The series comprises a number of titles, which cover procedures in angioplasty and stenting, transcatheter embolization and therapy, biopsy and drainage, ablation, pediatric interventional radiology and neurointerventional radiology. Each book is laid out in bullet point format, so that the desired information can be located quickly and easily. Interventional radiologists at all stages, from trainees through to specialists, will find this book a valuable asset for their practice.Interventional Radiology Techniques in Ablation is a practical and concise guide to contemporary techniques in image-guided tumor ablation. This handbook is intended to serve as a quick reference for physicians in interventional radiology training as well as a resource for IR technologists, nurses, nurse practitioners and physician assistants.
  • Preparing for successful and safe procedures -- Interventional pause -- Contrast -- Sedation -- Pain control and analgesia -- Drugs used in interventional radiology -- Non-invasive vascular imaging -- Angiography -- getting the picture -- Equipment for angiography -- Using catheters and wires -- Vascular access -- Haemostasis -- Complications of angiography and vascular intervention -- Angiographic diagnosis -- Angioplasty and stenting -- Stents and stent-grafts -- Endovascular aneurysm repair (EVAR) -- Embolization -- Thrombolysis and thrombectomy -- Venous intervention -- Haemodialysis access -- imaging and intervention -- Rendezvous and retrieval procedures -- Imaging guidance for intervention -- Equipment for non-vascular intervention -- Biopsy and drainage -- Percutaneous renal intervention -- Biliary intervention -- Percutaneous fluoroscopic gastrostomy -- Gastrointestinal stent insertion -- Tumour ablation -- Respiratory system.
  • As many as 80% of patients will suffer from back pain at some point in their lifetime. It is the most common form of disability, and the second largest cause of work absenteeism. An early, proactive management approach offers the best route to minimizing these conditions. Renowned authority Curtis W. Slipman, MD and a team of multidisciplinary authorities present you with expert guidance on today's best non-surgical management methods, equipping you with the knowledge you need to offer your patients optimal pain relief. Refresh your knowledge of the basic principles that must be understood before patients with spinal pain can be properly treated. Know what to do when first-line tests and therapies fail, using practice-proven diagnostic and therapeutic algorithms. Offer your patients a full range of non-surgical treatment options, including pharmacology, physical therapy, injection techniques, ablative procedures, and percutaneous disc decompression. Make an informed surgical referral with guidance on indications, contraindications, methods, and postoperative rehabilitation. Better understand key techniques and procedures with visual guidance from more than 500 detailed illustrations. Download all of the book's illustrations from the accompanying CD-ROM for use in electronic presentations.
  • Internal carotid artery occlusion / O. Jansen -- Middle cerebral artery occlusion / C. Reidel -- Vertebrobasilar occlusion / D. Morhard and G. Schulte-Altedorneburg -- Dissections / T. Boeckh-Behrens -- Cerebral venous and sinus thrombosis / J. Linn -- Thrombolysis : intravenous thrombolysis / G. F. Hamann -- Intra-arterial thrombolysis / B. Eckert -- Mechanical recanalization materials : aspiration thrombectomy -- A. Kreusch and M. Knauth -- Temporary stenting in stroke patients / J. Klisch -- Retrievers and other thrombectomy systems / T. Struffert and A. Dörfler -- Treatment concepts and results : carotid-T occlusion / G. Fesl -- Occlusion of the middle cerebral artery / T. Liebig -- Basilar artery thrombosis / G. Schulte-Altedorneburg and H. Brückmann -- Cervical artery dissections / A. Rohr and H. Görike -- Treatment of acute cerebral venous occlusions / T. E. Mayer -- Equipment : stents, filters, and balloon systems / M. Holtmannspötter -- Extracranial carotid stenoses / M. Tietke and O. Jansen -- Intracranial stenoses / W. Kurre -- Subclavian steal syndrome / A. Berlis -- Proximal vertebral artery stenosis / N. Lummel and H. Brückmann -- Proximal stenosis of supra-aortic vessels / J. Berkefeld.
  • General aspects of interventional ultrasound. Interventional ultrasound: introduction and historical background -- Interventional materials and equipment -- Informed consent -- Medications, equipment, and setup requirements -- Pathology and cytology -- Fine needle aspiration cytology -- Infections and diganostic microbiology -- Hygiene management -- Contraindications, complications, and complication management -- Assistance in ultrasound interventions -- Sedation in interventions -- Specifc ultrasound-guided procedures: abdomen. Indications for diagnostic interveions in the abdomen and thorax (liver, pancreas, spleen, kidneys, lung, other sites) -- Diagnostic and therapeutic paracentesis of free abdominal fluid -- Fine needle aspiration biopsy and core needle biopsy -- Abscess drainage -- Percutaneous sclerotherapy of cysts -- Interventional treatment of echinococcosis -- Local ablative procedures: percutaneous ethanol and acetic acid injection -- Local ablative procedures for liver tumors, radiofrequency ablation -- Percutaneous transhepatic cholangiodrainage -- Percutaneous gastrostomy -- Interventional endosonography -- Special issues regarding interventions in the spleen -- Specific ultrasound-guided procedures: thorax. Thoracic interventions -- Specific ultrasound-guided procedures: urogenital system. Percutaneous renal biopsy -- Interventional urology -- Specific ultrasound -guided procedures: other organ systems. Interventional thyroid ultrasound -- Musculskeletal interventions -- Neurologic interventions, ultrasound-guided regional anesthesia -- Utlrasound-guided emergency and vascular interventions -- Specific ultrasound-guided procedures: other applications of interventional ultrasound. Extravascular use of ultrasound contrast agents -- Volume navigation -- Palliative interventions and the role of ultrasonography in palliative care.
  • Interventions in Pulmonary Medicine is an important new volume that addresses all areas of interventional pulmonology, a minimally invasive endoscopic way to diagnose and treat lung disorders. This volume contains dedicated chapters that outline the many issues related to lung cancer, both in early and advanced stages, from diagnosis to personalized treatment. It also covers bronchoscopic therapeutic options to benign conditions that are highly prevalent, such as COPD and asthma. Techniques described in this volume are: laser therapy, argon plasma coagulation therapy, cryotherapy, brachytherapy, placement of intrapleural drainage systems, endoscopic treatment of emphysema, stents in the airway, and thermoplasty for bronchial asthma. Diagnostic procedures that are covered are: medical thoracoscopy, flexible and rigid bronchoscopy, endobronchial ultrasound, electromagnetical navigation, and trends in personalized treatment for lung cancer and other benign lung conditions. Chapters are written by experts and the developers of the techniques that are currently considered gold standard. Evidence-based reviews are presented for all topics and indications, and contraindications are discussed. Interventions in Pulmonary Medicine is a must have for pulmonologists, endoscopists, pulmonary oncologists, ENT physicians, thoracic surgeons, anesthesiologists, and intensive care specialists and their teams.
  • The intervertebral disc is composed of a complex tissue that separates neighboring vertebrae, permits a wide range of motion, and cushions the high biomechanical forces on the spine. Disc degeneration leads to a loss of function and is often associated with excruciating pain. Written by leading scientists and clinicians, this is the only book in the past fifty years devoted entirely to the study of the intervertebral disc. The first part of the book provides a review of the basic biology of the disc in health and disease. The second part considers strategies for mitigating the effects of disc degeneration and discusses the possibility of engineering replacement tissues. The final section is dedicated to approaches that model normal development, and the elucidation of the pathogenesis of degenerative disc disease using animal, organ and cell culture techniques. This unique and authoritative book bridges the gap between the basic and clinical sciences; its target audience includes basic scientists, orthopedists, neurologists, rehabilitation and physical therapists, primary care physicians and chiropractors, while it also addresses the needs of graduate students, medical students, interns, fellows, and patients who suffer from disc-related pathologies.
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  • Intestinal absorption
    Wellcome Trust
  • This volume acquaints the non-neuropathologist with the advantages of clinical-radiologic-pathologic correlation in neuropathology specimens, particularly in the intra-operative environment. This volume covers the enormous and sometimes insurmountable artifacts involed with freezing tissue, especially central nervous system tissue and how a good cytology preparation can add to, or even supply in isolation, a diagnosis. The text presents how to perform, and stain the cytologic preparations, and how to interpret them. The advantages and disadvantages of both frozen sections and cytologic preparations of various kinds are discussed. The presentation and format is very visual with diagrams, tables (including pearls and pitfalls), and many figures (therefore easy reading).An introductory chapter presents the pros and cons of supplemental cytology, the advantages and disadvantages of frozen sections, and the artifacts in both. Also included is an argument for knowing what the scans reveal and the impact of relevant patient history. The volume uses a case-based approach to show correlation between scan, history, frozen section and cytologic preparations.With the combination of extensive correlation of scans, cytology and frozen section with differential diagnosis, and analysis of the information crucial to the neurosurgeon in a case-based approach and with a special chapter written by a neuroradiologist, this volume is unique in presentation and utility and will be of great value to the trainee in pathology (residents/fellows), and practicing pathologists who include neuropathology in their practice, but do not have formal fellowship training in neuropathology.
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    Introduction -- Atrial chambers: gross anatomy and intracardiac phased-array echocardiography imaging -- Interatrial septum -- Role of intracardiac echocardiography for ablation of ventricular tachycardia -- Abnormal anatomy: left atrial structures -- Intracardiac echocardiography during catheter ablation for atrial fibrillation -- Transcatheter occlusion of left atrial appendage for stroke prevention in atrial fibrillation--potential role for intracardiac echocardiography -- Intracardiac echocardiography: transseptal catheterization -- Right atrium: ICE in anatomic definition, mapping and ablation -- Intracardiac echocardiography in the congenital catheterization laboratory -- Intrapericardial echocardiography: a novel catheter-based approach to cardiac imaging -- Three-dimensional echocardiography--future applications in interventional cardiology -- Future of image-guided therapies in interventional electrophysiology.
  • The volume includes 75 papers which were presented at the Third International Conference on Intracerebral Hemorrhage, held in Rancho Mirage, California, in March 2010. The topics treated include animal models, pathophysiology of cerebral hemorrhage, experimental treatment for cerebral hemorrhage, cerebral hemorrhage clinical manifestations, prognosis of cerebral hemorrhage, and clinical management. The articles represent the recent advances in hemorrhagic brain injury research presented by highly respected laboratories around the world.
  • "In the face of rapid development and impressive improvements in endovascular technology and techniques, there remain a large number of intracranial aneurysms for which microvascular surgery remains either the only or the preferable management option. Additionally, the complications of endovascular treatment have generated a unique subset of aneurysms requiring special surgical skills. Preparation to meet the challenges raised by all of these lesions begins with assimilation of basic aneurysm surgical techniques and the development of a conceptual framework for their use. The most reliable training ground for excellent microsurgical technique remains cerebrovascular disease in general and aneurysm surgery in specific. Furthermore, despite the wide-spread availability of lengthy texts that address all aspects of intracranial vascular pathologies, there seems to remain a persistent demand for nitty-gritty technical advice presented in a consistent, straight-forward, didactic format"--Provided by publisher.
  • Digitised ICP over Three Decades -- Latency Relationships Between Cerebral Blood Flow Velocity and Intracranial Pressure -- The Linear Relationship Between Transcranial Doppler Pulsatility Indices and Intracranial Pressure Is Influenced by Traumatic Brain Injury and Vasospasm -- Time Constant of the Cerebral Arterial Bed -- Pulse Amplitude and Lempel-Ziv Complexity of the Cerebrospinal Fluid Pressure Signal -- Association Between ICP Pulse Waveform Morphology and ICP B Waves -- Computerized Data Analysis of Neuromonitoring Parameters Identifies Patients with Reduced Cerebral Compliance as Seen on CT -- Early Warning of EUSIG-Defined Hypotensive Events Using a Bayesian Artificial Neural Network -- Trigger Characteristics of EUSIG-Defined Hypotensive Events -- Go Green! Reusing Brain Monitoring Data Containing Missing Values: A Feasibility Study with Traumatic Brain Injury Patients -- Investigation of the Relationship Between Transcranial Impedance and Intracranial Pressure -- Bioinformatics Analysis of Mortality Associated with Elevated Intracranial Pressure in Children -- A Versatile Software for Assessment of CSF Dynamics -- Modified Brainstem Auditory Evoked Responses in Patients with Non-brainstem Compressive Cerebral Lesions -- Analysis of Intracranial Pressure Time Series Using Wavelets (Haar Basis Functions) -- Stationarity in Neuromonitoring Data -- Is ICP Solid or Fluid? In Vitro Biomechanical Model Using a Fluid-Saturated Gel -- Implantable ICP Monitor for Improved Hydrocephalus Management -- Intracranial Pressure Telemetry: First Experience of an Experimental In Vivo Study Using a New Device -- Telemetric ICP Measurement with the First CE-Approved Device: Data from Animal Experiments and Initial Clinical Experiences -- The New ICP Minimally Invasive Method Shows That the Monro-Kellie Doctrine Is Not Valid -- Non-Invasively Estimated ICP Pulse Amplitude Strongly Correlates with Outcome After TBI. Realization of a Comprehensive Non-invasive Detection of Intracranial Pressure Analyzer Based upon FVEP and TCD -- Electrophysiological Monitoring of Cochlear Function as a Non-invasive Method to Assess Intracranial Pressure Variations -- Autoregulatory Model Comparison and Optimisation Methodology -- Assessment of Cerebral Autoregulation from Respiratory Oscillations in Ventilated Patients After Traumatic Brain Injury -- Monitoring of the Association Between Cerebral Blood Flow Velocity and Intracranial Pressure -- How Does Moderate Hypocapnia Affect Cerebral Autoregulation in Response to Changes in Perfusion Pressure in TBI Patients? -- Correlation of Clinical Outcome and Angiographic Vasospasm with the Dynamic Autoregulatory Response After Aneurysmal Subarachnoid Hemorrhage -- Comparison of a New Brain Tissue Oxygenation Probe with the Established Standard -- Comparing Brain Tissue Oxygen Measurements and Derived Autoregulation Parameters from Different Probes (Licox vs. Raumedic) -- Experimental Comparison of the Measurement Accuracy of the Licox® and Raumedic® Neurovent-PTO Brain Tissue Oxygen Monitors -- Is PbrO2 Pressure Reactivity Index (ORx) Dependent on the Type of Oxygen Probe? An In Vivo Study -- Continuous Quantitative Monitoring of Cerebral Oxygen Metabolism in Neonates by Ventilator-Gated Analysis of NIRS Recordings -- Near Infrared Spectroscopy as Possible Non-invasive Monitor of Slow Vasogenic ICP Waves -- Drift of the Bowman Hemedex® Cerebral Blood Flow Monitor Between Calibration Cycles -- Quantification of Pulsatile Cerebrospinal Fluid Flow within the Prepontine Cistern -- Delta-ADC (Apparent Diffusion Coefficient) Analysis in Patients with Idiopathic Normal Pressure Hydrocephalus -- Evidence for Altered Spinal Canal Compliance and Cerebral Venous Drainage in Untreated Idiopathic Intracranial Hypertension -- Automated Extraction of Decision Rules for Predicting Lumbar Drain Outcome by Analyzing Overnight Intracranial Pressure -- Lack of Correlation of Overnight Monitoring Data and Lumbar Infusion Data in iNPH Patients. Shunt-Dependent Hydrocephalus Following Subarachnoid Hemorrhage Correlates with Increased S100B Levels in Cerebrospinal Fluid and Serum -- Normal Hypocretin-1 (Orexin A) Levels in Cerebrospinal Fluid in Patients with Idiopathic Intracranial Hypertension -- Frontal and Temporal Horn Ratio: A Valid and Reliable Index to Determine Ventricular Size in Paediatric Hydrocephalus Patients? -- Intraventricular Cooling During CSF Infusion Studies -- An Uncommon Case of Idiopathic Intracranial Hypertension with Diagnostic Pitfalls -- Micro-fabricated Shunt to Mimic Arachnoid Granulations for the Treatment of Communicating Hydrocephalus -- On the Method of a Randomised Comparison of Programmable Valves with and Without Gravitational Units: The SVASONA Study -- Idiopathic Normal Pressure Hydrocephalus: Results of a Prospective Cohort of 236 Shunted Patients -- Idiopathic Normal Pressure Hydrocephalus (iNPH) and Co-Morbidity: An Outcome Analysis of 134 Patients -- Intracranial Pressure Measurement in Infants Presenting with Progressive Macrocephaly and Enlarged Subarachnoid Spaces -- Treatment Options for Intracranial Arachnoid Cysts: A Retrospective Study of 69 Patients -- A Microdialysis Study of Oral Vigabatrin Administration in Head Injury Patients: Preliminary Evaluation of Multimodality Monitoring -- The Atrial Natriuretic Peptide Does Not Serve Osmoregulation but Predicts Outcome Following Brain Injury -- Bedside Study of Cerebral Critical Closing Pressure in Patients with Severe Traumatic Brain Injury: A Transcranial Doppler Study -- Traumatic Brain Injury in the Elderly: A Significant Phenomenon -- Fixed, Dilated Pupils Following Traumatic Brain Injury: Historical Perspectives, Causes and Ophthalmological Sequelae -- Why Mortality Is Still High with Modern Care of 613 Evacuated Mass Lesions Presented as Severe Head Injuries 1999-2009 -- Late Decompressive Craniectomy as Rescue Treatment for Refractory High Intracranial Pressure in Children and Adults -- CT Angiography as a Confirmatory Test in Brain Death. The Imaging Diagnosis and Prognosis Assessment of Patients with Midbrain Injury in the Acute Phase of Craniocerebral Injury -- The Effect of Intraventricular Thrombolysis in Combination with Low-Frequency Head Motion After Severe Subarachnoid Hemorrhage: Interim Analysis of Safety, Clot Clearance Rate and Delayed Cerebral Ischemia -- Early CT Perfusion Measurement After Aneurysmal Subarachnoid Hemorrhage: A Screening Method to Predict Outcome? -- Cerebrospinal Fluid Lactate Concentration After Withdrawal of Metabolic Suppressive Therapy in Subarachnoid Hemorrhage -- Effect of Increased ICP and Decreased CPP on DND and Outcome in ASAH -- Prior Statin Use Has No Effect on Survival After Intracerebral Hemorrhage in a Multiethnic Asian Patient Cohort -- The Impact of Silver Nanoparticle-Coated and Antibiotic-Impregnated External Ventricular Drainage Catheters on the Risk of Infections: A Clinical Comparison of 95 Patients -- Dependence of Cerebrospinal Fluid Pressure and Volume on the Changes in Serum Osmolarity in Cats -- The Effect of Body Position on Intraocular and CSF Pressures in the Lateral Ventricle, and in Cortical and Lumbar Subarachnoid Spaces in Cats -- Pressure Reactivity Index Correlates with Metabolic Dysfunction in a Porcine Model of Intracerebral Hemorrhage -- Evidence of Spreading Depolarizations in a Porcine Cortical Intracerebral Hemorrhage Model -- Spontaneous Cortical Spreading Depression and Intracranial Pressure Following Acute Subdural Hematoma in a Rat -- The Peptide AF-16 and the AF Protein Counteract Intracranial Hypertension -- Influence of Isoflurane on Neuronal Death and Outcome in a Rat Model of Traumatic Brain Injury -- Correlation of the Intracranial Pressure to the Central Venous Pressure in the Late Phase of Acute Liver Failure in a Porcine Model -- Visualisation of Cortical pO2 During an Epidural Mass Lesion in Rodents -- Development of an Experimental Model to Study the Pathophysiology of Cerebral Salt Wasting Following Subarachnoid Hemorrhage.
  • Stereotactic radiosurgery from notion to practice / Erik-Olof Backlund -- Radiobiology of stereoatactic radiosurgery / John C. Flickinger -- How brain tumors respond to stereoatactic radiosurgery / György T. Szeifert ... [et al.] -- Image-guided stereoatactic radiosurgery / Jasvinder Nangiana, John R. Adler Jr., and Steven D. Chang -- Stereoatactic radiosurgery for arteriovenous malformations / L. Dade Lunsford ... [et al.] -- Stereoatactic radiosurgery for dural arteriovenous fistulas / Michael Söderman ... [et al.] -- Stereoatactic radiosurgery for cavernomas / Bengt Karlsson and Michael Söderman -- Stereoatactic radiosurgery for meningiomas / Douglas Kondziolka ... [et al.] -- Stereoatactic radiosurgery for pituitary adenomas / Jay Jagannathan ... [et al.] -- Stereoatactic radiosurgery for skull base chordomas and chondrosarcomas / Jean-Louis Habrand ... [et al.] -- Stereoatactic radiosurgery for glomus tumors / Jeffrey T. Jacob ... [et al.] -- Stereoatactic radiosurgery for vestibular schwannomas / Nicholas Massager and Marc Levivier -- Stereoatactic radiosurgery for nonvestibular schwannomas / Ajay Niranjan ... [et al.] -- Stereoatactic radiosurgery for trigeminal neuralgia / Jean Régis ... [et al.] -- Stereoatactic radiosurgery for movement disorders / Joel Bauman and John Y.K. Lee -- Stereoatactic radiosurgery for epilepsy / Mark Quigg and Nicholas M. Barbaro -- Stereoatactic radiosurgery for ocular disorders / Roman Lis̆c̆ák and Gabriela Śimonová -- Stereoatactic radiosurgery for gliomas / Gregory J.A. Murad and William A. Friedman -- Stereoatactic radiosurgery for brain metastases / Mayur Jayarao, Lawrence S. Chin, and William F. Regine -- Stereoatactic radiosurgery for pediatric brain tumors / Simon S. Lo, Gene H. Barnett, and John H. Suh.
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  • Understanding the murine cutaneous dendritic cell network to improve intradermal vaccination strategies -- Insight into the immunobiology of human skin and functional specialization of skin dendritic cell subsets to innovate intradermal vaccination design -- Delivery systems for intradermal vaccination -- Targeting skin dendritic cells to improve intradermal vaccination -- Intradermal rabies vaccination : the evolution and future of pre- and post-exposure prophylaxis -- Intradermal vaccination to protect against yellow fever and influenza -- The dermis as a portal for dendritic cell-targeted immunotherapy of cutaneous melanoma -- DNA vaccines and intradermal vaccination by DNA tattooing
  • Intraductal papillary mucinous neoplasms (IPMNs) represent an opportunity to treat pancreatic tumors before they develop into aggressive, hard-to-treat cancers. Beginning with morphological classification and its clinical significance, natural history, and malignant change of both main duct and branch duct IPMNs, this book covers the whole field of IPMNs of the pancreas. It reviews the various methods of investigation: imaging, diagnostic investigation of cyst fluid, and those using pancreatic juice; and also examines aspects ranging from the development of malignancy to the timing and method of resection, focusing on both main duct and branch duct IPMNs. Aimed at residents, clinical fellows, and pancreatologists who treat patients with this common disease of the pancreas, this book is a landmark in the current understanding and future perspectives of IPMNs of the pancreas.
  • This book provides fundamental and practical knowledge in the treatment of fractures, healing disturbances and bone disorders with intramedullary nailing. It comprehensively discusses this biological and mechanical technique for appropriate indications and aims to ameliorate the standard of care for those patients who can benefit from intramedullary nailing. Its purpose is to guide the readers on the ?why, when, and how? for intramedullary nailing and is the first comprehensive resource to cover the actual know-how of this technique. Intramedullary Nailing: A Comprehensive Guide brings together a large number of experts and opinion leaders in the field of operative fracture care and reconstructive surgery to share their extensive experience with the readership of this book. Orthopedic trauma surgeons from all over the world, who work in many different circumstances and with the most diverse technical and logistical equipment, will find this book to be an essential resource and guide for utilizing this technique in clinical practice.
  • Site-2 protease at ten -- Signal peptide peptidases -- GXGD-type intramembrane proteases -- Rhomboid intramembrane serine proteases -- Proteases of the Rhomboid family in the yeast Saccharomyces cerevisiae -- [gamma]-Secretase and Alzheimer's disease -- [gamma]-Secretase mediated proteolysis: at the cutting edge of notch signaling.
  • "When a patient is under anesthesia, every second counts. An intraoperative consultation provides essential information to ensure every operation has a successful conclusion. The stakes are high and the challenges are great -- no special stains, limited access for consultation with colleagues, often suboptimal slide preparation, and cases that may be out of a pathologist's normal sphere of practice. Diagnostic Pathology: Intraoperative Consultation is designed to be the best resource when pathologists need assistance. No time is wasted looking for information because each chapter is directed to a specific question posed by a surgeon, such as 'Does this patient have pancreatic cancer?', 'Is there an intrauterine pregnancy?', 'Does this patient have lung cancer?', or 'Are the margins free of carcinoma?' The clinical setting and what the surgeon needs to know -- and why -- are explained. Specimen processing (gross and microscopic), tissue selection, and reporting of results are detailed. All major entities in the differential diagnosis are described and shown in photographs. Major pitfalls are discussed and illustrated. This is the book every pathologist will want at their side the next time a page calls them to the frozen section room"--Provided by publisher.
  • Intraoperative Echocardiography - a volume in the exciting new Practical Echocardiography Series edited by Dr. Catherine M. Otto -provides practical, how-to guidance on intraoperative echocardiography in adult and pediatric patients. Definitive, expert instruction from Dr. Donald C. Oxorn is presented in a highly visual, case-based approach that facilitates understanding and equips you to master this difficult technique while overcoming the unique challenges and risks it presents. Master challenging and advanced intraoperative echocardiography techniques such as epiaortic echocardiography and 3-D echocardiography through a practical, step-by-step format that provides a practical approach to image acquisition and analysis, technical details, pitfalls, and case examples. Reference the information you need quickly thanks to easy-to-follow, templated chapters, with an abundance of figures and tables that facilitate visual learning. Become an expert in echocardiographic evaluation of complex valvular heart disease, congenital heart disease, and intravascular devices in patients undergoing cardiac surgery and interventional cardiology procedures.
  • From vision to reality: the origins of intraoperative MR imaging -- Development of intraoperative MRI: a personal journey -- Lows and highs: 15 years of development in intraoperative magnetic resonance imaging -- Intraoperative imaging in neurosurgery: where will the future take us? -- Development and design of low field compact intraoperative MRI for standard operating room -- Low field intraoperative MRI in glioma surgery -- Intraoperative MRI (ioMRI) in the setting of awake craniotomies for supratentorial glioma resection -- Glioma extent of resection and ultra-low-field iMRI: interim analysis of a prospective randomized trial -- Impact of a low-field intraoperative MRI on the surgical results for high-grade gliomas -- Intraoperative MRI and functional mapping -- Information-guided surgical management of gliomas using low-field-strength intraoperative MRI -- Implementation of the ultra low field intraoperative MRI PoleStar N20 during resection control of pituitary adenomas -- Intraoperative MRI for stereotactic biopsy -- The evolution of iMRI utilization for pediatric neurosurgery: a single center experience -- Implementation and preliminary clinical experience with the use of ceiling mounted mobile high field intraoperative magnetic resonance imaging between two operating rooms -- High-field iMRI in glioblastoma surgery: improvement of resection radicality and survival for the patient? -- Image guided aneurysm surgery in a Brainsuite ioMRI Miyabi 1.5 T environment -- From intraoperative angiography to advanced intraoperative imaging: the Geneva experience -- Intraoperative magnetic resonance imaging -- 3 T ioMRI: the Istanbul experience -- Intraoperative 3.0 T magnetic resonance imaging using a dual-independent room: long-term evaluation of time-cost, problems, and learning-curve effect -- Multifunctional surgical suite (MFSS) with 3.0 T iMRI: 17 months of experience -- Intraoperative MRI at 3.0 Tesla: a movable magnet -- One year experience with 3.0 T intraoperative MRI in pituitary surgery -- Intraoperative computed tomography -- Intraoperative CT in spine surgery -- O-arm guided balloon kyphaplasty: preliminary experience of 16 consecutive patients -- Intraoperative imaging with 3D ultrasound in neurosurgery -- Intraoperative 3-dimensional ultrasound for resection control during brain tumor removal: preliminary results of a prospective randomized study -- Advantages and limitations of intraoperative 3D ultrasound in neurosurgery: technical note -- Integrated intraoperative room design -- Multimodal navigation integrated with imaging -- Multimodality imaging suite: neo-futuristic diagnostic imaging operating suite marks a significant milestone for innovation in medical technology -- Improving patient safety in the intraoperative MRI suite suing an on-duty safety nurse, safety manual and checklist -- Operating room integration and telehealth -- Intraoperative robotics: NeuroArm -- Clinical requirements and possible applications of robot assisted endoscopy in skull base and sinus surgery -- Robotic technology in spine surgery: current applications and future developments -- Microscope integrated indocyanine green video-angiography in cerebrovascular surgery -- Application of intraoperative indocyanine green angiography for CNS tumors: results on the first 100 cases -- A technical description of the brain tumor window model: an in vivo model for the evaluation of intraoperative contrast agents.
  • Image-guided therapy (IGT) uses imaging to improve the localization and targeting of diseased tissue and to monitor and control treatments. During the past decade, image-guided surgeries and image-guided minimally invasive interventions have emerged as advances that can be used in place of traditional invasive approaches. Advanced imaging technologies such as magnetic resonance imaging (MRI), computed tomography (CT), and positron emission tomography (PET) entered into operating rooms and interventional suites to complement already-available routine imaging devices like X-ray and ultrasound. At the same time, navigational tools, computer-assisted surgery devices, and image-guided robots also became part of the revolution in interventional radiology suites and the operating room. Intraoperative Imaging and Image-Guided Therapy explores the fundamental, technical, and clinical aspects of state-of the-art image-guided therapies. It presents the basic concepts of image guidance, the technologies involved in therapy delivery, and the special requirements for the design and construction of image-guided operating rooms and interventional suites. It also covers future developments such as molecular imaging-guided surgeries and novel innovative therapies like MRI-guided focused ultrasound surgery. IGT is a multidisciplinary and multimodality field in which teams of physicians, nurses, and other professionals, such as physicists, engineers, and computer scientists, collaborate in performing these interventions, an approach that is reflected in the organization of the book. Contributing authors include members of the National Center of Image-Guided Therapy program at Brigham and Womens Hospital and international leaders in the field of IGT.
  • General rationale and historical perspective -- Rationale and historical perspective of intraoperative irradiation -- Biology of large dose per fraction irradiation -- Methods and techniques of treatment -- Intraoperative electron beam irradiation: physics and techniques -- HDR-IORT: physics and techniques -- Electronic brachytherapy/low KV-IORT: physics and techniques -- IORT with electron-beam, high-dose-rate brachytherapy or low-KV/electronic brachytherapy: methodological comparisons -- Normal tissue tolerance: IORT -- Normal-tissue tolerance to IOERT, EBRT, or both: animal and clinical studies -- Results of IORT alone or plus EBRT by disease site -- Central nervous system tumors -- Head and neck cancer -- Breast cancer -- Lung cancer -- Gastric cancer -- Pancreas cancer -- Bile duct and gallbladder cancer -- Primary colorectal cancer -- Recurrent colorectal cancer -- Retroperitoneal sarcomas -- Extremity and trunk soft-tissue sarcomas -- Bone sarcomas -- Gynecologic malignancies -- Genitourinary cancer -- Pediatric malignancies -- Conclusions and future possibilities -- Conclusions and future possibilities: IORT.
  • "Intraoperative MR-Guided Neurosurgery contains detailed coverage of this state-of-the-art technology from the pioneers who developed it. World-renowned neurosurgeons and neuroradiologists combine their collective wisdom and experience to demonstrate how MR-guided neuronavigation can be used to view real-time images of a patient's brain during surgery to help remove tumors with greater precision. The authors provide step-by-step descriptions of how to perform procedures, including advice based on their clinical results. Readers will learn about the advantages and drawbacks of the various MR imaging systems, clinical indications for MR-guidance, anesthesia considerations, safety concerns related to working in a magnetic environment, and much more"--Provided by publisher.
  • Basis of intraoperative neurophysiological monitoring -- Generation of electrical activity in the nervous system and muscles -- Practical aspects of recording evoked activity from nerves, fiber tracts and nuclei -- Anatomy and physiology of sensory systems -- Monitoring somatosensory evoked potentials -- Monitoring auditory evoked potentials -- Monitoring visual evoked potentials -- Anatomy and physiology of motor systems -- Practical aspects of monitoring spinal motor systems -- Practical aspects of monitoring cranial motor nerves -- Anatomy and physiology of peripheral nerves -- Practical aspects of monitoring peripheral nerves -- Identification of specific neural tissue -- Intraoperative diagnosis and guidance in an operation -- Anesthesia and its constraints in monitoring motor and sensory systems -- General considerations about intraoperative neurophysiology and monitoring -- Equipment, recording techniques, and data analysis and stimulation -- Evaluating the benefits of intraoperative neurophysiological monitoring.
  • Clinical Evaluation of Labor and Intrapartum Sonography / Thomas Popowski, Patrick Rozenberg -- General Intrapartum Sonography Setup and Use in Labor / Miguel Angel Barber -- The Use of Two-Dimensional (2D) and Three-Dimensional (3D) Ultrasound in the First Stage of Labor / Ariel L. Zimerman -- Intrapartum Sonography and Labor Progression / Torbjørn Moe Eggebø -- Occiput Posterior Position and Intrapartum Sonography / Antonino F. Barbera -- Asynclitism: Clinical and Intrapartum Diagnosis in Labor / Antonino F. Barbera -- The Angle of Progression: An Objective Assessment of Fetal Head Descent in the Birth Canal / Antonino F. Barbera -- Head Rotation in Labor and Intrapartum Sonography Diagnosis with 2D and 3D / Tullio Ghi, Aly Youssef -- Intrapartum Translabial Ultrasound (ITU) to Assess Birth Progress / Boris Tutschek, Thorsten Braun -- Use of Cervical Length in Labor and Delivery / Sushma Potti -- Intrapartum Sonography and Clinical Risk Management / Andrea Tinelli, Sarah Gustapane -- New Technologies for Monitoring Labor Progress / Dan Farine -- Fetal Progression in Birth Canal: State of the Art / Anna Maria Dückelmann.
  • Management of ovarian cancer : the theory / Maurie Markman -- Management of ovarian cancer : clinical trials / Maurie Markman -- A systematic review and meta-analysis of randomized trials / Kenneth Jaaback -- Immunobiology and intraperitoneal immunobiologics in ovarian cancer / Ralph S. Freedman -- Intraperitoneal chemotherapy : technique and complications / Joan L. Walker -- Hyperthermia and chemotherapy : the science / Roger A. Vertrees, Jeffrey M. Jordan, and Joseph B. Zwischenberger -- Hyperthermic intraperitoneal chemotherapy in nongynecologic cancers / Bing Yi, Jason M. Foster, and Brian W. Loggie -- Peritoneal carcinomatosis of colorectal origin / Frans A.N. Zoetmulder -- Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for ovarian cancer : experience in France / Olivier Glehen and Francois-Noel Gilly -- Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for ovarian cancer : world experience / C. William Helm -- Techniques of delivering hyperthermic intraperitoneal chemotherapy / Jesus Esquivel, Paul H. Sugarbaker, and C. William Helm -- Future directions in the delivery of hyperthermic intraperitoneal chemotherapy / Scott Richard and Robert P. Edwards.
  • Current chemotherapy of ovarian cancer -- Principles of intraperitoneal chemotherapy -- Intraperitoneal chemotherapy: phase III trials -- Criteria for using intraperitoneal (IP) chemotherapy for advanced ovarian cancer -- Selection and placement of intraperitoneal catheters for IP chemotherapy for ovarian cancer -- Selection of drugs for intraperitoneal chemotherapy for ovarian cancer -- Administration guidelines for intraperitoneal chemotherapy for ovarian cancer -- Novel drugs for intraperitoneal therapy for ovarian cancer -- Cytoreductive surgery and perioperative intraperitoneal chemotherapy: an ongoing research effort -- Health-related quality of life and patient-reported outcomes.
  • Section 1. General considerations -- section 2. Implant devices -- section 3. Evidence-based practice -- section 4. Intrathecal drug delivery systems for spasticity -- section 5. Future of intrathecal drug delivery systems.
  • Introduction to fatty acids and lipids / Burdge, G.C., Calder, P.C. -- Fatty acids, lipid emulsions, and the immune and inflammatory systems / Miles, E.A., Calder, P.C. -- Importance of fatty acids in the perinatal period / Demmelmair, H., Koletzko, B. -- Commercial lipid emulsions and all-in-one mixtures for intravenous infusion : composition and physicochemical properties / Driscoll, D.F. -- In vivo handling and metabolism of lipid emulsions / Carpentier, Y.A., Deckelbaum, R.J. -- Parenteral lipids : safety aspects and toxicity / Wanten, G.J.A. -- Intravenous lipids in preterm infants : impact on laboratory and clinical outcomes and long-term consequences / Vlaardingerbroek, H., Van Goudoever, J.B. -- Intravenous lipid emulsions in term infants : impact on laboratory and clinical outcomes and long-term consequences / Hartman, C., Shamir, R. -- Intestinal failure-associated liver disease and the use of fish oil-based lipid emulsions / Goulet, O.J. -- Intravenous lipids in adult surgical patients / Klek, S., Waitzberg, D.L. -- Intravenous lipids in adult intensive care unit patients / Hecker, M., Mayer, K. -- Intravenous fish oil in adult intensive care unit patients / Heller, A.R. -- Intravenous lipids in home parenteral nutrition / Pironi, L., Agostini, F., Guidetti, M. -- The complexity of prescribing intravenous lipid emulsions / Waitzberg, D.L., Matos de Miranda Torrinhas, R.S. -- Use of intravenous lipids : what do the guidelines say? -- Singer, P., Theilla, M., Cohen, J.
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    This edition provides everything you need to administer IV medications quickly, accurately, and safely. ... [Includes] detailed information on 8 IV drugs recently approved by the FDA. --back cover.
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  • This book explains how to use intravitreal steroids optimally in the management of patients with intraocular inflammation (uveitis) and macular edema. The rationale for this treatment approach is first explained by examining the pathophysiology of these disease entities, with particular attention to the major role of inflammatory processes. Devices for the delivery of steroids to the eye are discussed, and guidance provided on the role of imaging studies before, during, and after steroid therapy. The value of different steroidal approaches is then considered in detail. Other topics addressed include the use of steroids as a surgical adjunct and within a combination strategy. Uveitis and macular edema are common sight-threatening diseases or complications of diabetes and retinal vein occlusion for which no adequate treatment was available until recently. Both trainees and practitioners will find Intravitreal Steroids to be an invaluable aid in combating these blinding diseases.
  • Intrinsic immunity 2013
    Springer
    The APOBEC3 Family of Retroelement Restriction Factors / Eric W. Refsland, Reuben S. Harris -- Inhibition of Retroviral Replication by Members of the TRIM Protein Family / Adam J. Fletcher, Greg J. Towers -- The Antiviral Activities of Tetherin / Stuart J. D. Neil -- Restriction of Retroviral Infection of Macrophages / Mark Sharkey -- Rapid Adversarial Co-Evolution of Viruses and Cellular Restriction Factors / Welkin E. Johnson -- RNA Interference-Mediated Intrinsic Antiviral Immunity in Plants / György Szittya, József Burgyán -- RNA Interference-Mediated Intrinsic Antiviral Immunity in Invertebrates / Arabinda Nayak, Michel Tassetto, Mark Kunitomi, Raul Andino -- Roles of MicroRNAs in the Life Cycles of Mammalian Viruses / Eva Gottwein -- Interplay Between DNA Tumor Viruses and the Host DNA Damage Response / Karyn McFadden, Micah A. Luftig.
  • The study of biological rhythms -- General features of rhythms : terminology and characteristics -- Physical and biological time -- Photoperiodism -- Biological oscillators and timers : models and mechanisms -- Tidal and lunar rhythms -- Sexuality and reproduction -- Natural resources and agriculture -- Veterinary medicine -- Society -- Clinical medicine -- Autorhythmometry -- Chronobiometry : analyzing for rhythms.
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  • Chapter 1. Introduction to enzymes, receptors and the action of small molecule drugs -- chapter 2. Protein structure and function -- chapter 3. The small molecule drug discovery process : from target selection to candidate selection -- chapter 4. Protein therapeutics (introduction to biopharmaceuticals) -- chapter 5. Similarities and differences in the discovery and use of biopharmaceuticals and small-molecule chemotherapeutics -- chapter 6. Therapies for type 2 diabetes : modulating the incretin pathway using small molecule peptidase inhibitors or peptide mimetics -- chapter 7. The structure and business of biopharmaceutical companies including the management of risks and resources -- chapter 8. Discovery and development of the anticancer agent gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase -- chapter 9. Targeting HER2 by monoclonal antibodies for cancer therapy -- chapter 10. Recombinant human erythropoietin and its analogues -- chapter 11. Lysosomal storage disorders : current treatments and future directions -- chapter 12. Hormone replacement therapy -- chapter 13. Design of the anti-HIV protease inhibitor darunavir -- chapter 14. The case of anti-TNF agents -- chapter 15. Discovery of the cholesterol absorption inhibitor, ezetimibe.
  • An Introduction to Biological Membranes: From Bilayers to Rafts covers many aspects of membrane structure/function that bridges membrane biophysics and cell biology. Offering cohesive, foundational information, this publication is valuable for advanced undergraduate students, graduate students and membranologists who seek a broad overview of membrane science. Brings together different facets of membrane research in a universally understandable mannerEmphasis on the historical development of the field. Topics include membrane sugars, membrane models, membrane isolation methods, and membrane transport.
  • ch. 1. Introduction -- ch. 2. Fundamentals of Light and Matter -- ch. 3. Basics of Biology -- ch. 4. Fundamentals of Light-Matter Interactions -- ch. 5. Principles of Lasers, Current Laser Technology, and Nonlinear -- ch. 6. Photobiology -- ch. 7. Bioimaging: Principles and Techniques -- ch. 8. Bioimaging: Applications -- ch. 9. Biosensors -- ch. 10. Microarray Technology for Genomics and Proteomics -- ch. 11. Flow Cytometry -- ch. 12. Light-Activated Therapy: Photodynamic Therapy -- ch. 13. Tissue Engineering with Light -- ch. 14. Laser Tweezers and Laser Scissors -- ch. 15. Nanotechnology for Biophotonics: Bionanophotonics -- ch. 16. Biomaterials for Photonics.
  • Cardiopulmonary exercise testing is an important diagnostic test in pulmonary medicine and cardiology. Capable of providing significantly more information about an individual's exercise capacity than standard exercise treadmill or 6-minute walk tests, the test is used for a variety of purposes including evaluating patients with unexplained exercise limitation or dyspnea on exertion, monitoring disease progression or response to treatment, determining fitness to undergo various surgical procedures and monitoring the effects of training in highly fit athletes. Introduction to Cardiopulmonary Exercise Testing is a unique new text that is ideal for trainees. It is presented in a clear, concise and easy-to-follow manner and is capable of being read in a much shorter time than the available texts on this topic. Chapters describe the basic physiologic responses observed during sustained exercise and explain how to perform and interpret these studies. The utility of the resource is further enhanced by several sections of actual patient cases, which provide opportunities to begin developing test interpretation skills. Given the widespread use of cardiopulmonary exercise testing in clinical practice, trainees in pulmonary and critical care medicine, cardiology, sports medicine, exercise physiology, and occasionally internal medicine, will find Introduction to Cardiopulmonary Exercise Testing to be an essential and one of a kind reference.
  • "The Practitioner's understanding of emergency medicine principles and practice, directly benefiting patient care in a variety of emergency settings An Introduction to Clinical Emergency Medicine, Second Edition is a much-needed resource for individuals practicing this challenging field. This textbook is novel in its approach to emergency medicine topics. It describes in detail the best and most current methods to care for patients in the emergency department, including initial evaluation, generation of differential diagnoses, problem solving, and management of challenging conditions based on presenting symptoms. Unlike other textbooks, in which the diagnosis is known, this textbook approaches clinical problems as clinicians manage patients - without full knowledge of the final diagnosis. It provides an understanding for how to approach patients with undifferentiated conditions, ask the right questions, gather historical data, utilize physical examination skills, and order and interpret appropriate laboratory and radiographic tests. This textbook also provides current management and disposition strategies with controversies presented, including pearls, pitfalls, and myths for topics covered. Chapters are written by nationally- and internationally respected clinicians, educators, and researchers in the field of emergency medicine. Second Edition of An Introduction to Clinical Emergency Medicine offers just the right combination of text, clinical images, and practical information for students, residents, physician assistants, nurse practitioners, and experienced physicians in all medical disciplines"-- Provided by publisher.
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  • ch. 1. Introduction, p. 1-10 -- ch. 2. Biochemical Data: Analysis and Management, p. 11-40 -- ch. 3. Biochemical Exploration: Internet Resources, p. 41-52 -- ch. 4. Molecular Graphics: Visualization of Biomolecules, p. 53-71 -- ch. 5. Biochemical Compounds: Structure and Analysis, p. 73-105 -- ch. 6. Dynamic Biochemistry: Biomolecular Interactions, p. 107-121 -- ch. 7. Dynamic Biochemistry: Enzyme Kinetics, p. 123-146 -- ch. 8. Dynamic Biochemistry: Metabolic Simulation, p. 147-163 -- ch. 9. Genomics: Nucleotide Sequences and Recombinant DNA, p. 165-182 -- ch. 10. Genomics: Gene Identification, p. 183-208 -- ch. 11. Proteomics: Protein Sequence Analysis, p. 209-231 -- ch. 12. Proteomics: Prediction of Protein Structures, p. 233-268 -- ch. 13. Phylogenetic Analysis, p. 269-284 -- ch. 14. Molecular Modeling: Molecular Mechanics, p. 285-314 -- ch. 15. Molecular Modeling: Protein Modeling, p. 315-341 -- Appendices.
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  • Overview of diagnostic modalities and contrast agents / Navid Zaer, Amini Behrang, and Khaled M. Elsayes -- Introduction to nuclear medicine / David Brandon, Aaron J. Thomas, and Gregory Ravizzini -- Diagnostic neuroradiology / Santosh Shah, Tara Hagopian, Robert Klinglesmith, and Eliana Bonfante -- Cardiothoracic imaging / Nakul Gupta, Sandra A. A. Oldham, and Eduardo J. Matta -- Gastrointestinal imaging / Patrick Marcin, Eduardo Matta, and Khaled M. Elsayes -- Genitourinary system / Usama Salem, Edwardo Matta, Ayda Youssef, and Khaled M. Elsayes -- Musculoskeletal / Behrang Amini and Zeyad Metwalli -- Interentional radiology / Bilal Anwer and Voon P. Liaw -- Pediatric radiology / Megan Speer, Michael Mahlmann, Jennifer Caero, and Ajaykumar Morani -- Introduction to womens imaging / Haitham Elsamaloty, Mohamed Al-Natour, Neda Haswah, Stephanie Holz, and Khaled Elsayes.
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  • Measures of disease occurrence -- Estimates of associations -- Age standardization -- Causes of diseases -- Descriptive epidemiology in public health -- Descriptive epidemiology in genetic epidemiology -- Descriptive epidemiology in clinical epidemiology -- Design options -- Follow-up studies -- Case-control studies -- The cross-sectional study -- The randomized controlled trial (RCT) -- Analytical epidemiology in public health -- Analytical epidemiology in genetic epidemiology -- Analytical epidemiology in clinical epidemiology -- Confounding and bias -- Confounding -- Information bias -- Selection bias -- Making inference and making decisions -- Sources of error in public health epidemiology -- Sources of error in genetic epidemiology -- Sources of error in clinical epidemiology -- P values -- Calculating confidence intervals -- Erratum to: an introduction to epidemiology for health professionals.
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  • Introduction to epilepsy 2006
    NCBI Bookshelf
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    1. The Genetics Revolution in the Life Sciences -- pt. I. TRANSMISSION GENETICS -- 2. Single-Gene Inheritance -- 3. Independent Assortment of Genes -- 4. Mapping Eukaryote Chromosomes by Recombination -- 5. The Genetics of Bacteria and Their Viruses -- 6. Gene Interaction -- pt. II. FROM DNA TO PHENOTYPE -- 7. DNA: Structure and Replication -- 8. RNA: Transcription and Processing -- 9. Proteins and Their Synthesis -- 10. Gene Isolation and Manipulation -- 11. Regulation of Gene Expression in Bacteria and Their Viruses -- 12. Regulation of Gene Expression in Eukaryotes -- 13. The Genetic Control of Development -- 14. Genomes and Genomics -- pt. III. MUTATION, VARIATION, AND EVOLUTION -- 15. The Dynamic Genome: Transposable Elements -- 16. Mutation, Repair, and Recombination -- 17. Large-Scale Chromosomal Changes -- 18. Population Genetics -- 19. The Inheritance of Complex Traits -- 20. Evolution of Genes and Traits.
  • Review of organic chemistry -- Energy considerations in biochemical reactions -- Proteins -- DNA -- Transcription and translation -- Chromosomes and gene regulation -- Genetic variation -- DNA technology -- Cell division -- Cell cycle control, cell death, and cancer -- Expression microarrays -- Classification -- Clustering -- Genetic regulatory networks -- Intervention -- External intervention based on optimal control theory.
  • Understanding the basics I. The history of health care in the United States pre-1965 / Alexander Ding -- Medicare and its evolution to 2011 / Kevin J. Bozic and Benedict U. Nwachukwu -- Medicaid and the state children's health insurance program / Vasanth Sathiyakumar, Jordan C. Apfeld, and Manish K. Sethi -- Breaking down health care insurance from HMO to PPO and beyond / David Polakoff and Audrey Smolkin -- Understanding quality and cost from a health policy perspective / Jason D. Keune and Bruce Lee Hall -- Understanding the basics II. Prevention and US health care / Heather A. Smith -- The rise of comparative effectiveness research / Michael Hochman and Danny McCormick -- Health information technology : clinical and policy context / Emily R. Maxson and Sachin H. Jain -- Prescription drug and pharmaceutical policy / Phillip A. Choi and Walid F. Gellad -- Health disparities / Neil M. Issar and Manish K. Sethi -- The economics of health care / David A. Rosman and Jordan C. Apfeld -- Understanding systems of health care. The American health-care system : understanding how the pieces come together / Roshan P. Shah and Samir Mehta -- Alternative systems of care and consumer-driven health care / Daniel Guss -- National healthcare systems : a worldview / Benjamin S. Hooe, Perrin T. Considine, and Manish K. Sethi -- Reimbursement : understanding how we pay for health care / Sachin H. Jain and Elaine Besancon -- Understanding the politics in health policy. How health-care policy is made in Washington : understanding the players and the game / Eleby R. Washington IV, Ilisa Halpern Paul, Amy L. Walker, and A. Alex Jahangir -- Government and state agencies : who administrates healthcare on federal and state levels? / Rishin J. Kadakia and Hassan R. Mir -- The 2006 Massachusetts health care reform / Vasanth Sathiyakumar, Jordan C. Apfeld, Cesar S. Molina, Daniel J. Stinner, Andrew Han, and Manish K. Sethi -- The 2010 Patient Protection and Affordable Care Act : what is it and how will it change health care? / Richard Latuska, ALexandra Obremskey, and Manish K. Sethi.
  • The aim of this book volume is to explain the importance of Markov state models to molecular simulation, how they work, and how they can be applied to a range of problems. The Markov state model (MSM) approach aims to address two key challenges of molecular simulation: 1) How to reach long timescales using short simulations of detailed molecular models 2) How to systematically gain insight from the resulting sea of data MSMs do this by providing a compact representation of the vast conformational space available to biomolecules by decomposing it into states sets of rapidly interconverting conformations and the rates of transitioning between states.This kinetic definition allows one to easily vary the temporal and spatial resolution of an MSM from high-resolution models capable of quantitative agreement with (or prediction of) experiment to low-resolution models that facilitate understanding. Additionally, MSMs facilitate the calculation of quantities that are difficult to obtain from more direct MD analyses, such as the ensemble of transition pathways. This book introduces the mathematical foundations of Markov models, how they can be used to analyze simulations and drive efficient simulations, and some of the insights these models have yielded in a variety of applications of molecular simulation.
  • In the past, for the most part, people who moved into management positions in medical imaging were chosen because they were the best technologists. However, the skill set for technologists and supervisors/managers are vastly different. Even an MBA-educated person may not be ready to take on imaging management. As an example, when buying a very expensive piece of imaging equipment, this person would not necessarily know the right questions to ask, such as: What is my guaranteed uptime? Is technologist training included? Introduction to Medical Imaging Management is a comprehensive reference for.
  • Ch. 1. Light and matter -- ch. 2. Fundamentals of light and optics -- ch. 3. Types of microscopes -- ch. 4. Kohler illumination -- ch. 5. Sample preparation, manipulation, and micrometry -- ch. 6. Photomicrography -- ch. 7. Polarized light microscopy -- ch. 8. Basic crystallography -- ch. 9. Chemical microscopy.
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    Nanomedicine and nanobioengineering fuse nanotechnology with medicine and bioengineering. They are emerging new frontiers, providing challenges for fundamental research and opportunities for revolutionary advances in medical technology. They also provide a global vision to produce breakthrough approaches for meeting our current and future healthcare needs. Introduction to Nanomedicine and Nanobioengineering provides an integrated description of nanomedicine and nanobioengineering for next-generation diagnostics and therapy. It presents a basic introduction to a broad range of topics in an integrated manner, so that individuals in all disciplines in this field. It is intended to serve both as a textbook for education and training, as well as a reference book that aids further advancement in areas integrating nanotechnology with medicine and bioengineering. The book encompasses the fundamentals of nanomaterials design, bioengineering, nanodiagnostics, and nanotherapy. It is intended to benefit investigators adn students from the disciplines of chemistry, physics, and dental school trainees adn practitioners, and scientists from the pharmaceutical and cosmetic industries.
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  • This book is a primer for nurses on the topic of nursing informatics and presents the fundamental concepts of health information management from a nursing perspective. Nursing informatics has never been more important as contemporary healthcare offers exciting opportunities for the nursing profession to contribute to the design of emerging eHealth models of care and to ensure resources such as electronic health records and mobile technology are pragmatic and fit for purpose. This new edition contains the best available evidence to inspire and support nurses to think critically about both current and future practice. Introduction to Nursing Informatics is designed for use by practicing nurses and students in undergraduate programs of study and includes a number of contributions from leading international experts who have practiced in the field over a number of years. The information is presented and integrated in a purposeful manner to encourage readers to explore the key concepts of nursing practice, information management and its relationship to informatics. Critically, the content is also linked to case-based examples to contextualize the theory presented.
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  • "Proteomics provides an introductory insight on proteomics, discussing the basic principles of the field, how to apply specific technologies and instrumentation, and example applications in human health and diseases. With helpful study questions, this textbook presents an easy to grasp and solid overview and understanding of the principles, guidelines, and especially the complex instrumentation operations in proteomics for new students and research scientists. Written by a leader in proteomics studies, Proteomics offers an expert perspective on the field and the future of proteomics"--Provided by publisher.
  • Historical antecedents -- Immune system basics -- Endocrine-immune modulation -- Neuroimmune modulation -- Stress, contextual change, and disease -- Psychosocial stress: neuroendocrine and immune effects -- Infection, allergy, and psychosocial stress -- Cancer, autoimmunity, and psychosocial stress -- Immune activity and psychopathology -- Immune function enhancement -- Integration and implications.
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    Introduction -- Essays on research in the health professions -- Ethics in research -- Regulatory protection of human subjects in research -- Funding the research : grants -- The research problem -- Review of the literature -- Methodology -- Clinical investigations -- Survey research -- The clinical review -- Qualitative research -- Community-based participatory research -- Data analysis -- Results -- Discussion -- References -- What to do with what you have -- Writing and publishing in the health professions -- Interpreting the literature.
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    Methods and health research: discussion, questions, and answers -- Research planning -- Sampling methods and external validity -- Causal research and internal validity: discussion, questions, and answers -- Experimental designs and intervention studies -- Surveys and quasi-experimental designs -- Single case (n=1) designs -- Qualitative research -- Questionnaire design -- Interview techniques and the analysis of interview data -- Observation -- Measurement: discussion, questions, and answers -- Organization and presentation of data -- Measures of central tendency and variability -- Standard scores and normal curve -- Correlation: discussion, questions, and answers -- Probability and sampling distributions -- Hypothesis testing -- Selection and use of statistical tests -- The interpretation of research evidence: Discussion, questions, and answers -- Qualitative data analysis -- Presentation of health science research -- Critical evaluation of published research -- Synthesis of research evidence.
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    Genetic counseling and the laws of probability -- Autosomal dominant inheritance -- Autosomal recessive inheritance -- X-linked recessive inheritance -- The use of linked DNA markers -- Germline mosaicism -- Polygenic and multifactorial inheritance -- Cancer genetics -- Balanced chromosome rearrangements -- Other mechanisms of inheritance.
  • I. Programming. Setting up -- R as a calculating environment -- Basic programming -- I/O: input and output -- Programming with functions -- Sophisticated data structures -- Better graphics -- Pointers to further programming techniques -- II. Numerical techniques. Numerical accuracy and program efficiency -- Root-finding -- Numerical integration -- Optimisation -- III. Probability and statistics. Probability -- Random variables-- Discrete random variables -- Continuous random variables -- Parameter estimation -- IV. Simulation -- Monte-Carlo integration -- Variance reduction -- Cases studies -- Student projects -- Glossary of R commands -- Programs and functions developed in the text.
  • This introductory book presents a comprehensive outline of spine surgery that will provide operating room personnel, spine fellows, spine residents, and other multidisciplinary team members with a firm understanding of the general science concepts, equipment, and key procedures in spinal patient care. Clearly presented figures, illustrations, and photographs illuminate procedural techniques at preoperative, intraoperative, and postoperative stages of treatment.
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  • "While the public health philosophy of the 20th Century -- emphasizing prevention -- is ideal for addressing natural disease outbreaks, it is not sufficient to confront 21st Century threats where adversaries may use biological weapons agents as part of a long-term campaign of aggression and terror. Health care providers and public health officers are among our first lines of defense. Therefore, we are building on the progress of the past three years to further improve the preparedness of our public health and medical systems to address current and future BW [biological warfare] threats and to respond with greater speed and flexibility to multiple or repetitive attacks." Homeland Security Presidential Directive 21 Bioterrorism is not a new threat in the 21st century -- thousands of years ago the plague and other contagious diseases were used in warfare -- but today the potential for catastrophic outcomes is greater than it has ever been. To address this threat, the medical and public health communities are putting various measures in place, including systems designed to pro-actively mon- itor populations for possible disease outbreaks"--Provided by publisher.
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    Introduction to clinical trials -- Defining the question -- Study design -- Sample size -- Randomization -- Data collection and quality control -- Survival analysis -- Longitudinal data -- Quality of life -- Data monitoring and interim analysis -- Selected issues in the analysis -- Closeout and reporting.
  • ch. 1. The Evolution of survey process quality -- ch. 2. The Survey process and data quality -- ch. 3. Coverage and nonresponse error -- ch. 4. The Measurement process and its implications for questionnaire design -- ch. 5. Errors due to interviewers and interviewing -- ch. 6. Data collection modes and associated errors -- ch. 7. Data processing: errors and their control -- ch. 8. Overview of survey error evaluation methods -- ch. 9. Sampling error -- ch. 10. Practical survey design for minimizing total survey error.
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    An historical context / Sidney Bloch and Edwin Harari -- Ethical aspect of psychotherapy practice / Allen R. Dyer and Sidney Bloch -- Research in psychotherapy / Frank Margison and Anthony Bateman -- What is psychotherapy? / Jerome D. Frank -- Individual long-term psychotherapy / Susan Mizen and Jeremy Holmes -- Short-term dynamic psychotherapy / Michael Hobbs -- Cognitive psychotherapy / Nicholas B. Allen -- Behavioural psychotherapy / Lynne M. Drummond and Brett Kennedy -- Crisis intervention / Cynthia Graham and John Bancroft -- Supportive psychotherapy / Sidney Bloch -- Group psychotherapy / Mark Aveline -- Cognitive analytic therapy / Ian B. Kerr and Anthony Ryle -- The conversational model / Russell Meares -- Child and adolescent psychotherapy / Ricky Emanuel -- Psychotherapy with older adults / Jane Garner -- Couple psychotherapy / Michael Crowe -- Sex therapy / John Bancroft -- Family therapy in the adult psychiatric setting / Edwin Harari and Sidney Bloch.
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    Introduction -- Health care workforce -- Hospitals and other health care institutions -- Primary and ambulatory care -- Government and the health care system -- Financing -- Health care system performance -- From prepaid group medical practice to managed care -- Health care reform.
  • This book provides a readable introduction to modern toxicology with a particular focus on the mechanisms underlying the induction of toxicity by foreign substances. Since bioactivation is central to many toxic syndromes, special interest is devoted to chemicals that undergo conversion to toxic metabolites that induce toxic effects as diverse as cancer, birth defects and organ injury. The molecular consequences accompanying damage to cellular DNA and proteins is explored together with the relevance of toxicological paradigms to human diseases caused by alcohol and tobacco. The discipline of toxicology has developed rapidly since the thalidomide disaster in the 1960?s as scientists worldwide seek to understand the adverse health effects of human medicines, environmental pollutants, consumer chemicals and industrial reagents. An Introduction to Toxicology is intended to supplement the recommended reading list of undergraduate and graduate programs in toxicology and pharmacology as an enjoyable, accessible primer with illustrations that "unpack" the concepts being discussed in the text.
  • Introduction: What Is Translational Research -- Insights into heart development and regeneration -- Basis Of Cell Excitability And Cardiac Conduction System -- The Renin-Angiotensin-Aldosterone System In Cardiovascular Diseases -- Beta adrenergic receptors -- The hypothalamic-pituitary-adrenal axis in human health and disease -- Genetic Polymorphisms -- Genetic Polymorphisms and the Vascular Endothelium -- The role of microRNAs in Cardiovascular Disease -- Pathways To Myocardial Hypertrophy -- The multiple actions of the insulin-like growth factor-I signaling in the myocardium -- Calcium Cycling Circuits in Cardiac Physiology and Pathophysiology -- Inflammation and atherosclerosis -- Stress proteins and the Adaptive Response of the Heart -- The Mechanisms And Modalities Of Cell Death -- Repair of the infarcted myocardium -- Pathways to cardiac remodeling -- A Translational Approach to Probe the Arrhythmic Potential of the Heart: Therapeutic Considerations -- Animal Models Of Cardiovascular Disease -- Experimental in vitro assessment of cardiac function -- In vivo experimental assessment of cardiac function -- Non invasive imaging modalities for Cardiovascular Translational Research- Technical Considerations -- Cardiovascular Applications of Non-Invasive Imaging in Cardiovascular Diseases: from Bench to Bedside -- Molecular Imaging of Inflammation Using Echoardiography: Advances With the Use of Microbubbles -- Clinical Aspects And Genetics Of Cardiomyopathies -- Cardiorenal Syndrome: What Basic Research Can Contribute -- Clinical aspects of Cardiorenal Syndrome: consequences of therapy with the Renin-Angiotensin System Inhibitors -- Pre-, Peri-, and Post-Conditioning the ischemic myocardium: Challenges, Confounders and Expectations -- Gene Therapy for the Heart -- Cell therapy in cardiac diseases -- Moving Towards a Novel Paradigm in Drug Development for Worsening Heart Failure: The T1 Model (Mechanistic Translational Phase).
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    Health, health care, and the market economy -- Health care as a reflection of underlying cultural values and institutions -- The Health professions and the organization of health care -- Health insurance, HMOs, and the managed care revolution -- Medicare -- Medicaid and the State Children's Health Insurance Program -- The Increasing role of for-profit health care -- Pharmaceutical policy and the rising cost of prescription drugs -- Long-term care -- The Uninsured -- Factors other than health insurance that impede access to health care -- Key policy issues for deciding the direction of health care reform -- Where do we go from here? options for health care reform.
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  • "Now in its 6th edition, Introduction to Vascular Ultrasonography, by Drs. John Pellerito and Joseph Polak, provides an easily accessible, concise overview of arterial and venous ultrasound. A new co-editor and new contributors have updated this classic with cutting-edge diagnostic procedures as well as new chapters on evaluating organ transplants, screening for vascular disease, correlative imaging, and more. High-quality images, videos, and online access make this an ideal introduction to this complex and rapidly evolving technique."--Publisher's website.
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    Diagnosis and classification -- Interviewing and assessment -- The neurobiology and genetics of mental illness -- Delirium, dementia, and amnestic disorder -- Schizophrenia and other psychotic disorders -- Mood disorders -- Anxiety disorders -- Somatoform, dissociative, and related disorders -- Alcohol and drug-related disorders -- Personality disorders -- Sexual dysfunction, paraphilias, and gender identify disorders -- Eating disorders -- Adjustment disorders -- Impulse-control disorders -- Psychiatric emergencies -- Child psychiatry -- Sleep disorders -- Legal issues -- Psychological treatments -- Psychopharmacology and electroconvulsive therapy.
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    Diagnosis and classification -- Interviewing and assessment -- The neurobiology and genetics of mental illness -- Delirium, dementia, and amnestic disorder -- Schizophrenia and other psychotic disorders -- Mood disorders -- Anxiety disorders -- Somatoform, dissociative, and related disorders -- Alcohol- and drug-related disorders -- Personality disorders -- Sexual dysfunction, paraphilias, and gender identity disorders -- Eating disorders -- Adjustment disorders -- Impulse-control disorders -- Psychiatric emergencies -- Child psychiatry -- Sleep disorders -- Legal issues -- Behavioral, cognitive, and psychodynamic treatments -- Psychopharmacology and electroconvulsive therapy.
  • pt. 1. Invariants of behavior -- pt. 2. Neurodynamics of embodied behavior.
  • Chapter 1. Ultrasound, general considerations -- Chapter 2. The interventional cytopathologist -- Chapter 3. The thyroid gland -- Chapter 4. The parathyroid gland -- Chapter 5. The salivary glands -- Chapter 6. The head and neck, miscellaneous lesions -- Chapter 7. The lymph nodes -- Chapter 8. The breast -- Index.
  • Incidence of invasive fungal sinusitis has been increasing over the years. The understanding of its pathophysiology has improved with newer serological tests and diagnostic methods helping in earlier diagnosis and reducing patient morbidity. It was believed earlier that invasive fungal sinusitis is seen only in immune compromised patients but clinical reports suggest otherwise. More anti-fungal drugs are being added to improve incidence of patient survival. This book aims to compile all practical information about invasive fungal sinusitis into a single volume. Therefore, busy clinicians would not have to perform exhaustive literature studies to diagnose invasive fungal sinusitis. The book aims to provide an overview of diseases which could be mistaken for invasive fungal sinusitis and discuss how the management is different. Book sections consist of clinical, microbiological, serological, pathological, radiological and pharmacological features of the disease and its management. Each section is important in today's context as it dynamically alters the management of the patient. Early clinical suspicion and rapid microbiological, pathological and radiological diagnosis with aggressive treatment with surgical debridement and medical therapy leads to favorable outcomes.
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    1. Sciences générales de l'homme -- 2. Sciences juridiques, politiques et économiques -- 3. Sciences pures et appliquées -- 4. Sciences médicales, biomédicales, pharmaceutiques et vetinaires.
  • Beyond the cellular alphabet of learning and memory in invertebrates / Randolf Menzel and Paul R. Benjamin -- Action selection / M. Heisenberg -- Cognitive components of insect behavior / Martin Giurfa and Randolf Menzel --Exploring brain connectivity in insect model systems of learning and memory / Jürgen Rybak -- 'Decision making' in larval Drosophila / Michael Schleyer, Sören Diegelmann, Birgit Michels, Timo Saumweber and Bertram Gerber -- Optophysiological approaches to learning and memory in Drosphila melanogaster / Thomas Riemensperger and André Fiala -- Computational analyses of learning networks / Douglas A. Baxter, Enrico Cataldo and John H. Byrne -- Issues in invertebrate learning raised by robot models / Barbara Webb -- Mechanosensory learning and memory in Caenorhabditis elegans / Andrea H. McEwan and Catharine H. Rankin -- Molecular and cellular circuits underlying Caenorhabditis elegans olfactory plasticity / Joy Alcedo and Yun Zhang -- Thermosensory learning in Caenorhabditis elegans / Hirouyuki Sasakura and Ikue Mori -- Age-dependent modulation of learning and memory in Caenorhabditis elegans / Shin Murakami -- Salt chemotaxis learning in Caenorhabditis elegans / Yuichi Iino -- A systems analysis of neural networks underlying gastropod learning and memory / Paul R. Benjamin -- Comparison of operant and classical conditioning of feeding behavior in Aplysia / Riccardo Mozzachiodi, Douglas A. Baxter and John H. Byrne -- Mechanisms of short-term and intermediate-term memory in Aplysia / Robert D. Hawkins, Igor Antonov and Iksung Jin -- Synaptic mechanisms of induction and maintenance of long-term sensitization memory in Aplysia / David L. Glanzman -- Roles of protein kinase C and protein kinase M in Aplysia learning / Margaret Hastings, Carole A. Farah adn Wayne S. Sossin -- Multisite cellular and synaptic mechanisms in Hermissenda Pavlovian conditioning / Terry Crow and Nan Ge Jin -- Molecular and cellular mechanisms of classical conditioning in the feeding system of Lymnaea / Gyorgy Kemenes -- Operant conditioning of respiration in Lymnaea / Ken Lukowiak and Sarah Dalesman -- Associative memory mechanisms in terrestrial slugs and snails / Alan Gelperin -- Observational and other types of learning in Octopus / Piero Amodio and Graziano Fiorito -- The neurophysiological basis of learning and memory in advanced vertebrates / Binyamin Hochner and Tal Shomrat -- Learning, memory, and brain plasticity in cuttlefish (Sepia officinalis) / Ludovic Dickel, Anne-Sophie Darmaillacq, Christelle Joset-Alves and Cécile Bellanger -- A multidisciplinary approach to learning and memory in the crab Neohelice (Chasmagnathus) granulata / Daniel Tomsic and Arturo Romano -- Drosphila memory research through four eras / Seth M. Tomchik and Ronald L. Davis -- Visual learning and decision making in Drosphila melanogaster / Aike Guo, Huimin Lu, Ke Zhang, Qingzhong Rena nd Yah-num Chiang Wong -- In search of the engram in the honeybee brain / Randolf Menzel -- Neural correlates of olfactory learning in the primary olfactory center of teh honeybee brain / Jean-Christophe Sanidoz -- Mermory phases and signaling cascades in honeybees / Uli Muller -- Pheremones acting as social signals modulate learning in honeybees / Elodie Urlacher, Jean-Marc Devaud and Alison R. Mercer -- Extinction learning and memory formation in the honeybee / Dorothea Eisenhardt -- Glutamate neurotransmission and appetitive olfactory conditioning in the honeybee / Gérard Leboulle -- Cellular mechanisms of neuronal plasticity in the honeybee brain / Bernd Grünlatt -- Behavioral and neural analyses of punishment learning in honeybees / Stevanus Rio Tedjakumala and Martin Giurfa -- Breain aging and performance plasticity in honeybees / Daniel Munch and Gro V. Amdam -- Learning and recognitionof identity in ants / Patrizia D'ettorre -- Bounded plasticity in the desert ant's navigational tool kit / Rüdiger Wehner and Wolfgagn Rössler -- Learning and decision making in a social context / Nigel R. Franks and Ana B. Sendova-Franks -- Olfactory and visual learning in cockroaches and crickets / Makoto Mitzunami, Yukihisa Matsumoto, Hidehiro Watanabe and Hiroshi Nishino -- Individual recognition and the evolution of learning and memory in Polistes paper wasps / Elizabeth A. Tibbetts and Michael J. Sheehan.
  • 1. Contemporary religious violence -- 2. Millennial religions and terrorism -- 3. Domestic terrorist religions -- 4. International terrorist religions -- 5. Satanism -- 6. Vampirism -- 7. Syncretic religions -- 8. Ritualistic crime scenes -- 9. Intelligence strategies -- 10. Symbolic analysis : ritual homicide typology -- Glossary -- Index.
  • Patient-focused technology and the health care delivery system / Patricia Flatley Brennan -- CHESS : translating research into practice / Robert P. Hawkins and Susan Dinauer -- Theory and literature review / Robert P. Hawkins and John Fellows -- Considerations for successful implementation of newly adopted technologies / David H. Gustafson and John Fellows -- Implementation model development and testing / David H. Gustafson, Kuang-Yi Wen, and John Fellows -- Introduction to case studies / David H. Gustafson -- Associated Practice, 1992-1997 / Susan Dinauer, Pauley R. Johnson, Tracy Siegler, Gail Casper, and John Fellows -- Union Hospital, 1993-2001 / Susan Dinauer, Betta Owens, Tracy Siegler, Gail Casper, and John Fellows -- Strand Hardin Health Care, 1995-2002 / Tracy Siegler, Betta Owens, Gail Casper, and John Fellows -- Grace Hospital, 1996-2000 / Pauley R. Johnson, Robert P. Hawkins, Joanna Bates, Gail Casper, and John Fellows -- Simpson Hospital, 1997-2000 / Pauley R. Johnson, Susan Dinauer, Gail Casper, and John Fellows -- Caregiver Resource Center Network, 1999-2002 / Leah Eskenazi, Pauley R. Johnson, Tracy Siegler, Gail Casper, and John Fellows -- Key learning and advice for implementers / David H. Gustafson and Patricia Flatley Brennan.
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  • Ion channels methods and protocols 2006
    Springer Protocols
    A simple in-vivo method for assessing changes of membrane bound ion channel density in xenopus oocytes / Mouhamed S. Awayda ... [et al.] -- Preparation of cortical brain slices for electrophysiological recording / Costa M. Colbert -- Juxtacellular labeling and chemical phenotyping of extracellulary recorded neurons in vivo / Glenn M. Toney and Lynette C. Daws -- Carbon fiber amperometry in the study of ion channels and secretion / Duk-Su Koh -- Genetic screening for functionality of bacterial potassium channel mutants using K+ update-deficient escherichia coli / Lyubov V. Parfenova and Brad S. Rothberg -- KCNQ1 K channel-mediated cardiac channelopathies / Gildas Loussouarn, Isabelle Baro, and Denis Escade -- Tissue-specific transgenic and knockout mice / Andrée Porret ... [et al.]. Functional reconstitution of the human epithelial Na+ channel in a mammalian expression system / Alexander Staruschenko ... [et al.] -- Overexpression of proteins in neurons using replication-deficient virus / Richard M. Ahlquist and Jane M. Sullivan -- Exogenous expression of proteins in neurons using the biolistic particle delivery system / Nikita Gamper and Mark S. Shapiro -- Tertiary and quaternary structure formation of voltage-gated potassium channels / John M. Robinson, Andrey Kosolapov, and Carol Deutsch -- Biophysical approach to determine the subunit stoichiometry of the epithelial sodium channel using the xenopus laevis oocyte expression system / Farhad Kosari, Shaou Sheng, and Thomas R. Kleyman -- Spectroscopy-based quantitative fluorescence resonance energy transfer analysis / Jie Zheng -- Probing the effects of phosphoinositides on ion channels / Chou-Long Huang -- Epithelial sodium channel in planar lipid bilayers / Bakhrom K. Berdiev and Dale J. Benos --
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    v. 1. Levels -- v. 2. Effects.
  • Looks at the features and functions of the iPad2, covering such topics as accessing the Internet, setting up an email account, using built-in apps, playing games, using iTunes, watching videos, and syncing with MobileMe.
  • iPad for dummies 2010
    ProQuest Safari
    "Part iPod touch, part MacBook, part eReader, and all amazing, the iPad combines the best of your favorite gadgets into one ultraportable touch device. This handy guide helps you make the most of your iPad. From sending e-mail and surfing the Web to playing games, watching videos, downloading cool apps and more, the fun begins right here"--P. [4] of cover.
  • iPad made simple 2010
    ProQuest Safari
    Pt. I. Quick start guide -- pt. II. Introduction -- pt. 3. You and your iPad. Getting started -- Typing tips, copy/paste & search -- Sync your iPad with iTunes -- WiFi and 3G connections -- Moving, docking, and deletingicons -- Personalize and secure your iPad -- Playing music -- iBooks and E-books -- Viewing videos, tv shows, & more -- Bluetooth on the iPad -- Surf the web with Safari -- E-mail -- Working with contacts -- Your calendar -- Working with photos -- Maps -- Eliminate your paper notes -- iWork : productivity on your iPad -- iTunes on your iPad -- Amazing App Store -- Games and fun -- Social networking -- New media : reading newspapers, magazines, and more -- Other sync methods -- Troubleshooting -- pt. IV. iPad's soulmate : iTunes. Your iTunes user guide.
  • The use of structured frameworks in chemical risk assessment promotes transparent, harmonized approaches. This publication presents two IPCS frameworks originally published in Critical Reviews in Toxicology. Part 1 contains the IPCS Framework for Analyzing the Relevance of a Cancer Mode of Action for Humans, along with three case studies illustrating its application. Part 2 contains the IPCS Framework for Analyzing the Relevance of a Non-Cancer Mode of Action for Humans. The frameworks provide a means of ensuring a transparent evaluation of the data, identification of key data gaps and of information that would be of value in the further risk assessment of the chemical in question.--Publisher's description.
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    "This book is the first comprehensive history of Irish women in medicine in the late nineteenth and early twentieth centuries. It focuses on the debates surrounding women's admission to Irish medical schools, the geographical and social backgrounds of early women medical students, their educational experiences and subsequent careers. It is the first collective biography of the 760 women who studied medicine at Irish institutions in the period and, in contrast to previous histories, puts forward the idea that women medical students and doctors were treated fairly and often favourably by the Irish medical hierarchy. It highlights the distinctiveness of Irish medical education in contrast with that in Britain and is also unique in terms of the combination of rich sources it draws upon, such as official university records from Irish universities, medical journals, Irish newspapers, Irish student magazines, the memoirs of Irish women doctors, and oral history accounts." -- [Publisher-supplied data]
  • Iron Acquisition by the Genus Mycobacterium summarizes the early evidence for the necessity of iron in mycobacteria and the discovery of the mycobacterial siderophores mycobactin, carboxymycobactin, and exochelin. The structural characterization of the mycobacterial siderophores is described. The genes so far identified as essential for iron acquisition and maintenance of an infection by pathogenic mycobacteria are discussed. The potential role of siderocalin in iron gathering by M. tuberculosis is featured. Because new drugs for M. tuberculosis are needed, this brief also emphasizes the design of antibiotics that interfere with siderophore biosynthesis and the use of siderophore analogs and/or conjugates.
  • Cellular iron metabolism -- Proteins of iron homeostasis -- Cellar iron physiology -- Regulation of iron metabolism in mammalian cells -- Concentrating, storing, and detoxifying iron: the ferritins and and hemosiderin -- Iron physiology -- Iron nutrition -- Intestinal iron absorption -- Plasma iron and iron delivery to the tissues -- Iron salvage pathways -- Molecular regulation of systemic iron metabolism -- Erythroid iron metabolism -- Iron and the reticuloendothelial system -- Iron and the immune system -- Disorders of iron homeostasis: anemias -- Iron deficiency -- Liabilities of iron deficiency -- Anemia of inflammation and chronic disease -- Disorders of red cell production and the iron-loading anemias -- Disorders of iron homeostasis: iron overload and related conditions -- Pathology of hepatic iron overload -- Hepatic pathobioogy of iron overload -- HFE-associated hereditary hemochromatosis -- Non-HFE hemochromatosis -- Miscellaneous iron-related disorders -- Iron and liver disease -- Neuropathology and iron: central nervous system iron homeostasis -- Iron metabolism in cancer and infection -- Clinical diagnosis and therapy -- Estimation of body iron stores -- Genetic testing for disorders of iron homeostasis -- Properties of therapeutically useful iron chelators -- Clinical use of iron chelators -- Model systems for studying iron homeostasis -- Mammalian models of iron homeostasis -- Yeast iron metabolism -- Zebrafish models of heme synthesis and iron metabolism.
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    What is behavioral economics -- and why should we care? -- Keeping what we have, even if we don't like it -- Managing expectations and behavior -- Understanding the stubbornly inconsistent patient -- Understanding the stubbornly inconsistent consumer -- Understanding the medical decision making process, or, Why a physician can make the same mistakes as a patient -- Explaining the cumulative impact of physicians' decisions -- Can we use the concepts of behavioral economics to transform health care?
  • Irritant dermatitis 2006
    Springer
    I. Classification and clinical features -- 1. Ten genotypes of irritant contact dermatitis -- 2. Irritant contact dermatitis versus allergic contact dermatitis -- II. Special clinical forms -- 3. Barrier function and perturbation: relevance for interdigital dermatitis -- 4. Friction melanosis -- 5. Diaper dermatitis -- 6. Chemical skin burns -- 7. Contact urticaria syndrome -- 8. Airborne irritant dermatitis -- 9. Irritant dermatitis of the scalp -- 10. Irritant contact dermatitis of the nails -- III. Epidemiology -- 11. Importance of irritant contact dermatitis in occupational skin disease -- 12. Irritant contact dermatitis in the tropics -- IV. Occupational irritant dermatitis -- 13. Occupational issues of irritant contact dermatitis -- 14. Hairdressing -- 15. Occupational irritant dermatitis - metal workers -- 16. Health care workers -- 17. The Electronics industry -- 18. Painters, lacquerers, and varnishers -- V. Risk factors for irritant dermatitis -- 19. Age -- 20. Gender -- 21. Ethnicity -- 22. Atopy -- VI. Insights from bioengineering -- 23. Prediction bioengineering -- 24. Quantitative sonography for the evaluation of irritant reactions -- 25. Functional skin testing: the SMART procedures -- 26. Bioengineering correlates of the sensitive skin syndrome: the sensory irritation component -- 27. Squamometry -- VII. The Irritants: special issues -- 28. Corrosive materials -- 29. Detergents -- 30. Sodium lauryl sulfate -- 31. Organic solvents -- 32. Oils, cutting fluids, and lubricants -- 33. Food -- 34. Dithranol -- 35. Copper -- 36. Fatty acid binding proteins -- VIII. Mechanisms of irritant dermatitis -- 37. Histopathology of irritant contact dermatitis -- 38. Percutaneous absorption and irritant dermatitis -- 39 Cytokines and irritant dermatitis -- 40. Oxidative stress -- 41. Langerhans cells and skin irritation -- 42. Hydration injury -- IX. Prevention of irritant dermatitis -- 43. Primary prevention of irritant contact dermatitis -- 44. Protective gloves -- 45. Anti-irritants -- 46. Barrier creams -- 47. Moisturizers -- 48. Moisturizers and irritant contact dermatitis -- 49. Effects of CO2 on barrier recovery -- X. Management and therapy -- 50. Treatment of irritant contact dermatitis -- 51. Topical corticosteroids in the treatment of irritant dermatitis -- 52. Barrier creams and emollients -- XI. Product testing -- 53. In vivo models of skin irritation -- 54. In vitro methods to predict skin irritation -- XII. Appendices -- 1. Questionnaire methods for hand dermatitis studies -- 2. Patient information sheets -- 3. Selected sources of information for irritant contact dermatitis.
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    Is there an ethicist in the house? -- Call me doctor? Confessions of a hospital philosopher -- Arguing euthanasia -- Bioethics is a naturalism -- Ethics consultation as moral engagement -- Ethics by committee: the moral authority of consensus -- Goodbye to all that: the end of moderate protectionism in human subjects research -- Convenient and captive populations -- Regulation of research in the decisionally impaired -- "The only feasible means": the Pentagon's ambivalent relationship with the Nuremberg code -- Reassessing the influence of the Nuremberg code on American medical ethics -- Cancer, truth, and genetics -- Neuroethics: an agenda for neuroscience and society -- Bioethics after the terror -- Another impossible profession.
  • Breakthrough in stem cell research? : the reprogramming of somatic cells to pluripotent stem cells / Boris Greber, Hans Schöler -- Preimplantation stages of human development : the biological and moral status of early embryos / Maureen L. Condic -- Complete moles and parthenotes are not organisms / Nicanor Pier Giorgio Austriaco -- Embryos grown in culture deserve the same moral status as embryos after implantation / Joachim Huarte, Antoine Suarez -- Distinguishing embryos from non-embryos / Patrick Lee -- On the status of human embryos and cellular entities produced through ANT : are they persons? / Pablo Requena Meana -- Does a human being have a right to life? : the debate on embryo research in Germany as a case study / Manfred Spieker -- Interspecies mixtures and the status of humanity / Neville Cobbe -- The boundaries of humanity : the ethics of human-animal chimeras in cloning and stem cell research / William B. Hurlbut -- Is this cell entity a human being? : neural activity, spiritual soul, and the status of the inner cell mass and pluripotent stem cells / Antoine Suarez.
  • Ch. 1 "In vivo" manometric studies of the steady state intraocular pressure and the intraocular pressure pulse in animals and man -- Ch. 2 Rate of formation of the aqueous humor -- Ch. 3 Steady state intraocular pressure/flow relations in dead and living animal and human eyes -- Ch. 4 Homeostasis, autoregulation, and relative ischemia -- Ch. 5 Pressure/volume relation in eyes of dead and living animal and human eyes -- Ch. 6 Ocular perfusion pressure and its influence on the intraocular pressure pulse -- Ch. 7 Direct and indirect measurements of ocular blood flow in anesthetized and conscious animals and humans -- Ch. 8 Morphology and hydrodynamics of the chamber angle draining the aqueous humor -- Ch. 9 Sympathetic nerve innervation of the eye and the actions of the adrenergic neuron transmitter norepinephrine on intraocular pressure and ocular blood flow -- Ch. 10 Manometric studies on the intraocular pressure and vascular circulation in ophthalmic disease -- Ch. 11 Noninvasive studies on the IOP, PA and blood flow autoregulation in healthy and diseased eyes -- Ch. 12 Effect of posture and corneal thickness on the measurement of the intraocular pressure -- Ch. 13 The Langham pneumatic analogue and digitized tonometers -- Ch. 14 Calibration of the intraocular pressure and the intraocular pressure pulse using the Langham pneumatic tonometer -- Ch. 15 Theory of the Langham tonometer -- Ch. 16 Intraocular pressure/pulse amplitude relation in healthy animal and human eyes -- Ch. 17 Intraocular pressure/pulse amplitude relation and loss of autoregulation in ocular diseases -- Ch. 18 Autoregulation of the intraocular pressure and the ocular blood flow -- Ch. 19 Evaluation of ocular ischemia and the loss of autoregulation for the early detection of ocular vascular diseases -- Ch. 20 Action of drugs on ocular blood flow and on the intraocular pressure/pulse amplitude relation -- Ch. 21 Confluence and integration of therapies based on modulation of the intraocular pressure and ocular blood flow -- Ch. 22 Longitudinal therapeutic studies -- Ch. 23 Ophthalmodynamometry, the opthalmic arterial pressure and the effect of increased vascular resistance proximal and distal to the ophthalmic artery on ocular blood flow, the IOP/PA relation and vision -- Ch. 24 Ophthalmodynamometry -- Ch. 25 Autoregulation of the intraocular pressure and blood flow in the human eye -- Ch. 26 Objective measure of the diastolic and systolic ophthalmic arterial pressures -- Ch. 27 Ophthalmic arterial pressure in healthy subjects -- Ch. 28 Relation between the ophthalmic arterial pressure and the intraocular pressure/pulse amplitude relation -- Ch. 29 Modulation of the intraocular pressure/pulse amplitude relation in subjects with stenosis of the internal carotid artery -- Ch. 30 Alzheimer's disease and the eye -- Ch. 31 Ocular perfusion pressure and the visual threshold.
  • Structure of the Optic Nerve -- Blood Supply of the Optic Nerve -- Blood-Optic Nerve Barrier -- Factors Influencing the Optic Nerve Head Blood Flow -- Measurement of the Optic Nerve Head Blood Flow -- Terminology and Types of Ischemic Optic Neuropathy -- Optic Disc -- Clinical Evaluation of Patients with Ischemic Optic Neuropathies -- General Characteristics of Giant Cell Arteritis -- Clinical Features of Giant Cell Arteritis -- Diagnostic Criteria for Giant Cell Arteritis -- Ophthalmic Manifestations of Giant Cell Arteritis -- Management of Giant Cell Arteritis to Prevent Visual Loss -- Pathogenesis of Classical Non-arteritic Anterior Ischemic Optic Neuropathy -- Pathogenesis of Some Controversial Non-arteritic Anterior Ischemic Optic Neuropathy Clinical Entities -- Clinical Features of Non-arteritic Anterior Ischemic Optic Neuropathy -- Management of Non-arteritic Anterior Ischemic Optic Neuropathy -- Animal Model of Non-arteritic Anterior Ischemic Optic Neuropathy -- Classification and Incidence of Posterior Ischemic Optic Neuropathy -- Pathogenesis of Posterior Ischemic Optic Neuropathy -- Clinical Features of Posterior Ischemic Optic Neuropathy -- Management of Posterior Ischemic Optic Neuropathy.
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    The plot hinges on issues of medical ethics, infectious disease, and public safety.
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    Basic characteristics of isotopic tracers -- Calculating specific activity and radiation dosages -- Calculation of substrate kinetics : single-pool model -- Calculation of substrate kinetics : multiple-pool model -- Mass spectrometry : instrumentation -- Determination of isotopic enrichment -- Measurement of substrate oxidation -- Measurement of total energy expenditure using the doubly-labeled water method -- Mass isotopomer distribution analysis -- Glucose metabolism -- Lipid kinetics -- Whole body protein synthesis and breakdown -- Measurement of the synthesis of specific proteins -- Measurement of regional or tissue protein breakdown -- Arterial-venous balance technique to measure amino acid kinetics -- Nuclear magnetic resonance.
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    An overview of the dietetics professional's training and opportunities in healthcare / Robert S. DeChicco and Laura E. Matarese -- Dietetics education: past, present, and future / Deborah D. Canter -- Advanced-level and specialty practice: how necessary or beneficial are they for practitioners? / Julie O'Sullivan Maillet and Wanda H. Howell -- The economics of dietetic patient care / Elvira Q. Johnson, Chris Biesemeier, and Sylvia Escott-Stump -- Development of the dietetics professional's role as a member of a healthcare team / Beth Leonberg -- Is the dietetics professional an equal player on the healthcare team? / Robert F. Kushner ... [et al.] -- Global dietetics issues / Patricia S. Anthony -- Nutrition screening in acute care / Pam Charney -- Nutrition assessment / Marion F. Winkler and Riva Touger-Decker -- Measuring nutrient intake: are the tools valid for clinical practice and/or research? / Phyllis J. Stumbo -- Conducting research in a clinical practice setting / Esther F. Myers -- Informatics in the new healthcare environment / Syed S. Haque -- Genetics, nutrituional genomics, and dietetics practice: what the dietetics professional should know / Gail P.A. Kauwell -- Hypertension and clinical nutrition practice / Jennifer Muir Bowers -- Nutrition and coronary artery disease / Wanda H. Howell -- Obesity: the challenge for the healthcare professional / Abby S. Bloch -- Nutritional approaches to diabetes mellitus / Judith Wylie-Rosett -- Emerging issues in cancer care and nutrition / Cynthia A. Thomson -- Food-drug interactions / June H. McDermott and Carol J. Rollins -- Issues with alternative/complementary nutrition therapies: their role in clinical practices / Diane Rigassio Radler and Adam Perlman -- Implementing nutrient-based recommendations and dietary guidelines / Ricardo Uauy and Abby S. Bloch -- Global nutrient recommendations and food-based dietary guidelines: tables / Abby S. Bloch.
  • Part 1. How can we identify ictal and interictal abnormal activity? / Robert S. Fisher, Helen E. Scharfman, and Marco deCurtis -- What is the clinical relevance of in vitro epileptiform activity? / Uwe Heinemann and Kevin J. Staley -- What is the importance of abnormal "background" activity in seizure generation? / Richard J. Staba and Gregory A. Worrell -- What is a seizure focus? / J. Victor Nadler and Dennis D. Spencer -- What is a seizure network? Long-range network consequences of focal seizures / Hal Blumenfeld -- What is a seizure network? Very fast oscillations at the interface between normal and epileptic brain / Roger D. Traub, Mark O. Cunningham, and Miles A. Whittington -- Is there such a thing as "generalized" epilepsy? / Gilles van Luijtelaar, Charles Behr, and Massimo Avoli -- Part 2. Are there really "epileptogenic" mechanisms or only corruptions of "normal" plasticity? / Giuliano Avanzini, Patrick A. Forcelli, and Karen Gale -- When and how do seizures kill neurons, and is cell death relevant to epileptogenesis? / Ray Dingledine, Nicholas H. Varvel, and F. Edward Dudek -- How is homeostatic plasticity important in epilepsy? / John W. Swann and Jong M. Rho -- Is plasticity of GABAergic mechanisms relevant to epileptogenesis? / Helen E. Scharfman and Amy R. Brooks-Kayal -- Do structural changes in GABA neurons give rise to the epileptic state? / Carolyn R. Houser -- Does mossy fiber sprouting give rise to the epileptic state? / Paul S. Buckmaster -- Does brain inflammation mediate pathological outcomes in epilepsy? / Karen S. Wilcox and Annamaria Vezzani -- Are changes in synaptic function that underlie hyperexcitability responsible for seizure activity? / John G.R. Jefferys -- Does epilepsy cause a reversion to immature function? / Aristea S. Galanopoulou and Solomon L. Moshé -- Are alterations in transmitter receptor and ion channel expression responsible for epilepsies? / Kim L. Powell, Katarzyna Lukasiuk, Terence J. O'Brien, and Asla Pitkänen -- Part 3. How do we make models that are useful in understanding partial epilepsies? / David A. Prince -- Aligning animal models with clinical epilepsy: where to begin? / Stephen C. Harward and James O. McNamara -- What non-neuronal mechanisms should be studied to understand epileptic seizures? / Damir Janigro and Matthew C. Walker -- What epilepsy comorbidities are important to model in the laboratory? clinical perspectives / Simon Shorvon -- Epilepsy comorbidities: how can animal models help? / Carl E. Stafstrom -- What new modeling approaches will help us identify promising drug treatments? / Scott C. baraban and Wolfgang Löscher -- What are the arguments for and against rational therapy for epilepsy? / Melissa Barker-Haliski, Graeme J. Sills, and H. Steve White -- How can advances in epilepsy genetics lead to better treatments and cures? / Renzo Guerrini and Jeffrey Noebels -- How might novel technologies such as optogenetics lead to better treatments in epilepsy? / Esther Krook-Magnuson, Marco Ledri, Ivan Soltesz, and Merab Kokaia -- Index.
  • Breastfeeding and complementary feeding of children up to 2 years of age / K.H. Brown -- Does breastfeeding protect from growth acceleration and later obesity? / A. Singhal -- Later effects of breastfeeding practice: the evidence / D. Turck -- Traditional foods vs. manufactured baby foods / E.L. Ferguson, N. Darmon -- Potential contaminants in the food chain: identification, prevention and issue management / F.P. Scanlan -- The microbiological risk / L. Morelli -- Cereal fortification programs in developing countries / S. Bulusu ... [et al.] -- Processed infant cereals as vehicles of functional components / M. Domelléf, C. West -- Functional ingredients in the complementary feeding period and long-term effects / C. Agostoni, E. Riva, M. Giovannini -- The influence of gluten: weaning recommendations for healthy children and children at risk for celiac disease / S. Guandalini -- Allergic infants: growth and implications while on exclusion diets / K. Laitinen, E. Isolauri -- Weaning infants with malnutrition, including HIV / N.W. Solomons -- Adverse effects of cow's milk in infants / E.E. Ziegler -- Whole cow's milk: why, what and when? / K.F. Michaelsen ... [et al.] -- Meat as an early complementary food for infants: implications for macro- and micronutrient intakes / N.F. Krebs -- Functional fermented milk products / O. Brunser, M. Gotteland, S. Cruchet.

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