Books

I

  • 2013 Springer
    Atul C. Mehta, Prasoon Jain, editors.
    The field of interventional bronchoscopy is rapidly expanding and has emerged as a new and exciting subspecialty in pulmonary medicine. To date, the impact of interventional bronchoscopy procedures has been felt in diagnosis, staging, and management of lung cancer, the most lethal cancer worldwide. Interventional Bronchoscopy: A Clinical Guide provides a state-of-the art description of interventional bronchoscopy procedures, addressing the scientific basis, indications, techniques, results, complications, and cost issues.
  • 2013 ClinicalKey
    edited by Morton J. Kern.
    The newly updated Interventional Cardiac Catheterization Handbook helps you to effectively perform common therapeutic interventions. This convenient, pocket-sized handbook provides full-color illustrations and videos showcasing up-to-date, step-by-step methods for the most widely practiced interventional cardiology procedures! Review traditional procedures as well as more specialized interventions, including laser angioplasty, atherectomy, and stent implantation. Quickly access the information you need with the help of an easy-to-read outline format, which includes helpful tables and boldfaced key terms. An excellent complement to the 5th Edition of Kern's Cardiac Catheterization Handbook, the Interventional Cardiac Catheterization Handbook is also an ideal review tool for the boards.
  • 2005 Springer
    edited by Howard C. Herrmann.
    Percutaneous mitral balloon valvuloplasty for patients with rheumatic mitral stenosis : immediate and long-term followup results / Igor F. Palacios -- Balloon aortic and pulmonic valvuloplasty / Ted E. Feldman, Timothy A. Sanborn, and William W. O'Neill -- Pathophysiology and percutaneous coronary sinus repair of mitral regurgitation / Nicholas Valettas, Joseph H. Gorman III, and Robert C. Gorman -- Percutaneous coronary sinus approach to the treatment of mitral regurgitation / Fumiaki Ikeno ... [et al.] -- Percutaneous mitral valve repair with the edge-to-edge technique / Frederick G. St. Goar ... [et al.] -- Percutaneous valve insertion for the treatment of calcific aortic valve stenosis / Alain Cribier ... [et al.] -- Patent foramen ovale : neurological considerations / Steven R. Messa, Scott E. Kasner, and Anthony Furlan -- CardioSEAL, cardioSEAL-STARFlex, and PFO-star closure of PFO / Michael J. Landzberg -- Percutaneous closure of patent foramen ovale with the amplatzer PFO occluder : European experience / Andreas Wahl, Stephan Windecker, and Bernhard Meier -- Transcatheter closure of atrial septal defects using the amplatzer devices / Hitendra Patel ... [et al.] -- An overview of device closure of ventricular septal defects using the amplatzer devices / Ralf Holzer, Qi-Ling Cao, and Ziyad M. Hijazi -- Left atrial appendage occlusion / Mark Reisman -- Devices for myocardial preservation / Simon R. Dixon and William W. O'Neill -- Percutaneous mechanical assist devices / Suresh R. Mulukutla and Howard A. Cohen -- Alcohol septal ablation for hypertrophic obstructive cardiomyopathy / Haran Burri and Ulrich Sigwart -- Therapeutic angiogenesis and myocardial regeneration / G. Chad Hughes and Brian H. Annex -- Renal and iliac intervention / Michael T. Caulfield, Dharsh Fernando, and Kenneth Rosenfield -- Percutaneous carotid artery stenting / Cameron Haery and Jay S. Yadav -- Aortic stent grafting : percutaneous and surgical approaches / Omaida C. Velazquez, Edward Woo, and Ronald M. Fairman -- Interventional echocardiography / Frank E. Silvestry -- 3D angiography / Nathan E. Green ... [et al.] -- Interventional cardiovascular MRI : current status and future directions / Milind Y. Desai, Albert C. Lardo, and Joao A.C. Lima.
  • 2015 Springer
    Amr E. Abbas, editor.
    This book provides an overview of the current available invasive coronary imaging modalities, presenting a concise review of the technologies, indications, appropriate uses, and pitfalls. Since the establishment of invasive coronary angiography, the limitations of the technique have not gone unnoticed. As a result, multiple invasive imaging modalities have been developed in an attempt to characterize the true severity of coronary artery disease, and to guide percutaneous coronary interventions. The evolution of novel interventional imaging modalities is progressively altering our understanding of coronary artery disease diagnosis and prognosis. Interventional Cardiology Imaging: An Essential Guide is an invaluable tool for interventional cardiologists and cardiologists in training who wish to have a concise and practical review of all available modalities of invasive coronary imaging.
  • 2015 Springer
    Harald Rittger, editor.
    This book provides an in-depth review of current practices in the treatment of elderly patients with coronary artery disease. It presents an update of existing literature, reflecting the current science of elderly patients with stable angina, acute coronary syndromes, and patients who go on to receive coronary artery bypass grafting procedures. Evidence is often limited or non-existent in the elderly patient group. As such, the main challenge for further research is to define the role of geriatric preconditions and their impact on outcomes. This book aims to clarify if existing cardiological outcome values such as mortality can be applied to elderly patients, or if other values are more suitable parameters for measuring interventional success. Interventional Cardiology in the Elderly discusses the epidemiological, pathophysiological and ethical aspects of each of these topics and is hence an essential resource for all practicing interventional cardiologists.
  • 2012 Springer
    Thomas Kahn, Harald Busse, editors ; foreword by Maximilian F. Reiser.
    Systems for Interventional MRI / Stephen G. Hushek -- Pulse Sequences for Interventional MRI / Walter F. Block and Benjamin P. Grabow -- MR-Compatible Instruments for Interventional MRI / Harald H. Quick -- Navigation Techniques for MRI-Guided Interventions / Harald Busse, Thomas Kahn and Michael Moche -- Safety Considerations in Interventional MRI / Harald Kugel -- Anesthetic Concerns in the MR Environment / Ramon Martin -- MRI Guidance of Minimally Invasive Cranial Applications / Chip Truwit, Alastair J. Martin and Walter A. Hall -- MRI Guidance of Intracranial Tumor Resections / Daniela Kuhnt, Miriam H. A. Bauer, Oliver Ganslandt and Christopher Nimsky -- MRI Guidance of Musculoskeletal Interventions / Roberto Blanco Sequeiros, Jan Fritz and John A. Carrino -- High-Field Open MRI-Guided Interventions / Ulf K.-M. Teichgräber, Florian Streitparth and Felix V. Güttler -- MR-Guided Breast Interventions / Karin Hellerhoff and Clemens Cyran -- MRI Guidance of Vascular Applications / Gabriele A. Krombach -- Magnetic Resonance-Guided Embolization of Low-Flow Vascular Malformations / Sumera Ali, Clifford R. Weiss, Daniel P. Hsu and Jonathan S. Lewin -- MRI Guidance of Cardiac Applications / Tarique Hussain, Israel Valverde, Reza Razavi and Tobias Schaeffter -- MR-Guided Prostate Biopsy / Derya Yakar and Jurgen J. Fütterer -- MRI-Guided Therapeutic Procedures in Recurrent Prostate Cancer / David A. Woodrum, Akira Kawashima, Krzysztof R. Gorny and Lance A. Mynderse -- MRI-Guided Thermal Ablation Techniques / R. Jason Stafford and Kamran Ahrar -- MR Thermometry / Viola Rieke -- MRI-Guided Laser Ablation in the Liver / Christian Rosenberg and Norbert Hosten -- MRI-Guided RF Ablation in the Liver / Hansjörg Rempp, Rüdiger Hoffmann, Stephan Clasen and Philippe L. Pereira -- MRI-Guided RF Ablation in the Kidney / Sherif G. Nour and Jonathan S. Lewin -- MR-Guided Focused Ultrasound Treatment of Uterine Fibroids / Wladyslaw M. Gedroyc -- MRI-Guided High-Intensity Focused Ultrasound Sonication of Liver and Kidney / Baudouin Denis de Senneville, Mario Ries, Lambertus W. Bartels and Chrit T. W. Moonen -- MR-Guided Focused Ultrasound of the Brain / Rivka R. Colen and Ferenc A. Jolesz -- MRI-Guided Brachytherapy in the Liver / Uta Wonneberger, Frank Fischbach, Jürgen Bunke, Kerstin Jungnickel and Jens Ricke -- MRI-Guided Microwave Ablation / Shigehiro Morikawa, Shigeyuki Naka, Hiroyuki Murayama, Yoshimasa Kurumi and Tohru Tani, et al. -- MRI-Guided Stem Cell Therapy / Tina Ehtiati and Dara L. Kraitchman -- MR-Guided Delivery and Tracking of Cellular Therapeutics / Paul A. DiCamillo and Clifford R. Weiss -- Hybrid MRI Systems and Applications / Wesley D. Gilson and Frank Wacker -- Simultaneous Ultrasound Imaging and MRI Acquisition / Lorena Petrusca, Magalie Viallon, Sylvain Terraz, Valeria de Luca and Zarko Celicanin, et al. -- Simultaneous Endoscopy and MRI Acquisition / Hasnine A. Haque, Shigehiro Morikawa, Shigeyuki Naka, Yoshimasa Kurumi and Hiroyuki Murayama, et al.
  • 2014 Springer
    Samer N. Narouze, editor.
    Headache Classifications and Medically Resistant Headaches -- Algorithms for the Diagnosis and Management of Head and Face Pain -- Peripheral Nerve Block for the Management of Headache and Face Pain -- Occipital Nerve Blocks -- Occipital Neuralgia: The Role of Ultrasound in the Diagnosis and Treatment -- Glossopharyngeal Nerve Block -- Sphenopalatine Ganglion Block and Radiofrequency Ablation -- Trigeminal (Gasserian) Ganglion, Maxillary Nerve, and Mandibular Nerve Blocks -- Interventional Treatment for Trigeminal Neuralgia: Radiofrequency and Neuromodulation -- Practical Approach to Cervicogenic Headache -- Atlantoaxial Joint: Atlantoaxial Joint Injection and Radiofrequency Ablation -- Third Occipital Nerve Block and Radiofrequency Ablation -- Cervical Facet Syndrome: Cervical Medial Branch Block and Radiofrequency Ablation -- Intravenous Therapies for Intractable Headache -- Onabotulinum Toxin Injection and Headaches -- Epidural Blood Patch -- Occipital Nerve Stimulation for Head Pain: Surgical Leads -- Occipital Nerve Stimulation for Head Pain: Percutaneous Leads -- Sphenopalatine Ganglion Stimulation -- Deep Brain and Motor Cortex Stimulation for Head and Face Pain.
  • 2006 Springer
    S. Baba, Y. Ono (eds.).
  • 2014 Springer
    edited by Alexander S. Yevzlin, Arif Asif, Loay Salman.
    1. Pre-operative Evaluation -- History -- 2. Pre-operative Evaluation -- Physical Examination -- 3. Admission After Intervention -- When and Why -- 4. Communicating Effectively for Interventional Nephrologists -- 5. Anticoagulants and Thrombolytics -- 6. Non-invasive Screening and Testing for PAD in CKD patients -- 7. Overview of PAD Treatment in the CKD Population: Indications, Medical Strategies, and Endovascular Techniques -- 8. Unconventional Venous Access: Percutaneous Translumbar and Transhepatic Venous Access for Hemodialysis -- 9. Approach to a Non-Functioning Catheter -- 10. Approach to the Infected Catheter -- 11. Approach to a Patient Referred for Vascular Mapping -- 12. Approach to Arteriovenous Access -- 13. Approach to a Patient with Non-maturing AV Fistula -- 14. Approach to an Arteriovenous Access with Hyperpulsatile Pulse -- 15. Approach to an Arteriovenous Access with a Faint Thrill -- 16. Approach to an Arteriovenous Access with No Thrill, Bruit, or Pulse -- 17. Approach to Patient with Arteriovenous Access Presenting with Hand Pain -- 18. Central Vein Stenosis -- 19. Approach to a Patient with Pseudoaneurysm -- 20. Approach to Chest Pain During Dialysis -- 21. Approach to Cyanotic Digits and Hand Paresis -- 22. Approach to an Abnormal Surveillance Measurement -- 23. Arterial Stenosis Affecting Arteriovenous Fistulae and Grafts in Hemodialysis Patients: Approach to Diagnosis and Management -- 24. Approach to the Patient with Suspected Renal Artery Stenosis -- 25. Vascular Injury During Interventions -- 26. Pulmonary Embolism Associated with Dialysis Access Procedure -- 27. Stent Migration -- 28. Foreign Body Retrieval -- 29. Contrast and Medication Allergic Reactions -- 30. The Management of Serious Adverse Events Associated with Interventional Procedures -- 31. Preoperative Evaluation of a Patient for Peritoneal Dialysis Catheter -- Operative Considerations for Peritoneal Dialysis Catheter -- Approach to a Patient with Visceral Perforation.
  • 2014 Springer
    edited by Fergus Robertson, Kieran Murphy.
    The objective ofthe Techniquesin Interventional Radiology series is to provide easily accessible technique specific information on interventional radiology procedures, suitable for reference in the IR room or as a carry-around guide. Each volume has an EU and US editor so that the perspectives presented are balanced across these two major centres of interventional radiology. Each volume has a consistent template for easy and quick reference, with step-by-step bullet points, key point summaries at the end of each chapter and illustrations/line drawings as a visual aid. Interventional Neuroradiology will bring to the fore the collective wisdom of specialist interventional neuroradiologists, for their own reference and more crucially for the reference of trainees in interventional neuroradiology. This book will appeal to thosealready practisinginterventional neuroradiology and those taking fellowships in the speciality from neurology, neurosurgery or neuroradiology.
  • 2013 Springer
    Mario Muto, editor.
    Accurate interpretation of indications for treatment is the cornerstone of success in medicine. This book carefully examines the relation between clinical features, diagnosis, and choice of minimally invasive technique for a range of spine pathologies. It explains how selection of technique is intimately related to clinical and diagnostic aspects and how recognition of this relation forms the foundation for an optimal outcome. In addition to examining the various minimally invasive options, including the latest techniques, careful attention is paid to the role of medical treatment in avoiding recurrence after initial therapy. Nerve blocks, epidural injections, and intradiscal procedures are among the many options available in the armamentarium of the interventionalist, and advice is given on their use in different contexts.
  • 2015 Thieme-Connect
    [edited by] Ripal T. Gandhi, Suvranu Ganguli.
    Percutaneous ablation of renal cell carcinoma / Raul Uppot, Debra A. Gervais, and Shawn Ahmed -- Adrenal malignancy : ablation / Aradhana M. Venkatesan and Bradford J. Wood -- Ablation of lung cancer, pulmonary metastatic disease, and chest wall malignancy / Charles McGraw, Scott Genshaft, Fereidoun Abtin, Antonio Gutierrez and Robert Suh -- Hepatocellular carcinoma : ablation / Riccardo Lencioni -- Hepatocellular carcinoma : chemoembolization / Siddharth A. Padia and Matthew J. Kogut -- Hepatocellular carcinoma : radioembolization / Avnesh Thakor, Arash, Eftekhari, Ed Lee, Darren Klass, and David Liu -- Colorectal hepatic metastatic disease : ablation / Muneeb Ahmed -- Colorectal hepatic metastatic disease : intraarterial therapies / Govindanrajan Narayanan and Prasoon Mohan -- Carcinoid and neuroendocrine tumors : intraarterial therapies / Elena N. Petre, Karen T. Brown, and Constantinos T. Sofocleous -- Cholangiocarcinoma : ablation and intraarterial therapies / Paul J. Rochon, Charles E. Ray Jr., Rajan K. Gupta, and Matthew Brown -- Bone tumors : ablation / Matthew R. Callstrom and A Nicholas Kurup -- Portal vein embolization / Sanjeeva Kalva -- Emerging technologies (navigational systems, immunoembolization, percutaneous -- Hepatic perfusion/chemosaturation, ire) / Rahmi Oklu.
  • 2012 Springer
    Peter R. Mueller, Andreas Adam, editors.
    Interventional Oncology is a fast-growing new field, as well as an emerging specialty. Many minimally-invasive, imaging-guided procedures seem set to replace more traditional open surgical techniques of treating solid tumors in a variety of organs. The aim of this book is to describe new interventional radiological methods in a succinct and practical form. Diagnostic radiological considerations relevant to the selection and follow-up of patients are also covered. The book begins with an overview of the basic principles of current interventional techniques, including thermal ablation, high intensity focused ultrasound, and embolization. Later chapters focus on tumors of the liver, kidney, lung, and bone, placing new interventional techniques in context by referring to the surgical and oncologic methods of treating the same conditions. With an emphasis on best practices, Interventional Oncology: A Practical Guide for the Interventional Radiologist will serve as a definitive guide to practicing physicians involved in this rapidly evolving field.
  • 2008
    edited by Jean-Francois H. Geschwind and Michael C. Soulen.
    Status: Not Checked OutLane Catalog Record
  • 2011 Springer
    Bernhard Maisch ... [et al.] ; with contributions of Sabine Pankuweit ... [et al.].
  • 2014 ClinicalKey
    John M. Lasala, Jason H. Rogers.
    Apply the latest percutaneous techniques with the practical, highly illustrated Interventional Procedures for Structural Heart Disease. This brand-new medical reference book presents full-color images, numerous tables, and invaluable clinical pearls to help you utilize today's hottest techniques and technologies for each disease, so you can offer your patients the most desirable outcomes possible. Master today's hottest percutaneous procedures for structural heart disease as perfected by experts from around the world, including transcatheter aortic valve replacement (TAVR), percutaneous paravalvular leak closure, transcatheter mitral valve interventions, a wide variety of adult congenital cardiovascular defect interventions, and more.Grasp the specific knowledge you will need for success in a variety of clinical scenarios, as well as the patient selection criteria for each invasive procedure.Make informed, evidence-based decisions with the latest clinical trial results and evidence integrated into each chapter.Visualize the newest techniques and technologies more clearly through a full-color design featuring illustrations, tables, clinical pearls, complications, and current evidence boxes.
  • 2010
    edited by John F. Beamis, Jr., Praveen Mathur, Atul Mehta.
    Status: Not Checked OutLane Catalog Record
    New bronchoscopic instrumentation : a review and update in rigid bronchoscopy / Yarmus and Feller-Kopman -- Laser bronchoscoopy, electrosurgery, APC, and microdebrider / Bolliger -- Update on cryotherapy, brachytherapy, and photodynamic therapy / Lahm, Sheski -- Airway stents / Lee, Kupeli, Mehta -- High-resolution brochoscopy : bringing these modalities into focus / Riker -- Endoscopic staging of lung cancer / Yasufuku -- Medical thoracoscopy / Villanueva, Gonzalez -- Tunneled pleural catheters / MacEachern, Stather, Tremblay -- Bronchoscopic lung volume reduction in COPD / Diaz-Guzman, Mehta -- Bronchial thermoplasty / Mayse, Castro -- Sedation, analgesia and anesthesia for airway procedures / Nystrom, Mathur -- Advanced bronchoscopic techniques for diagnosis of peripheral pulmonary lesions / Lee, Ost -- Bronchoscopic treatment of peripheral lung nodules / Puchalskim Sterman -- Percutaneous dilational tracheostomy / Lamb -- Training in interventional pulmonology / Wang, Silvestri -- Role of bronchoscopy in lung transplant patients / von Garnier, Chhajed.
  • 2010 Thieme Book
    edited by Hector Ferral, Jonathan Lorenz.
  • 2011 ClinicalKey
    David Kessel, Iain Robertson ; with a contribution by Tarun Sabharwal.
    Preparing for successful and safe procedures -- Interventional pause -- Contrast -- Sedation -- Pain control and analgesia -- Drugs used in interventional radiology -- Non-invasive vascular imaging -- Angiography -- getting the picture -- Equipment for angiography -- Using catheters and wires -- Vascular access -- Haemostasis -- Complications of angiography and vascular intervention -- Angiographic diagnosis -- Angioplasty and stenting -- Stents and stent-grafts -- Endovascular aneurysm repair (EVAR) -- Embolization -- Thrombolysis and thrombectomy -- Venous intervention -- Haemodialysis access -- imaging and intervention -- Rendezvous and retrieval procedures -- Imaging guidance for intervention -- Equipment for non-vascular intervention -- Biopsy and drainage -- Percutaneous renal intervention -- Biliary intervention -- Percutaneous fluoroscopic gastrostomy -- Gastrointestinal stent insertion -- Tumour ablation -- Respiratory system.
  • 2007 Springer
    Bruno Kastler (editor) ; Fabrice-Guy Barral, Bernard Fergane, Philippe Pereira (co-editors) ; with contributions by Hatem Boulahdour ... [et al.] ; foreword by Georges Salamon.
  • 2016 Thieme-Connect
    [edited by] Jaime Tisnado, Rao R. Ivatury.
  • 2009 Thieme Book
    [edited by] Gary P. Siskin.
    This book is a practical resource for the current applications of interventional radiology in the care of female patients. Divided into seven main sections, the book opens with an introduction to the role of interventional radiology in women's health, discussing such topics as specific concerns relevant to the female patient and safety considerations related to the provision of care. The sections that follow address common clinical problems and conditions unique to women, including uterine fibroids, infertility, pelvic pain, osteoporosis, and varicose veins. A final section describes interventional procedures for treating breast cancer and offers key recommendations for further practice development.
  • 2016 Springer
    Josef Rösch.
    In this autobiography, Josef Rösch, a leading pioneer in interventional radiology from its inception to the present, documents his life and discusses important aspects of his work, focusing especially on those procedures that he developed or improved and that were popularized by his lectures and publications. In Prague, Dr. Rösch worked on splenoportography and visceral angiography, while in the United States he developed the transjugular intrahepatic portosystemic shunt (TIPS) and introduced embolization for treatment of GI bleeding and expandable metallic stenting of obstructions of major veins and the esophagus. In addition, he contributed to the improvement of coronary angiography and fallopian tube catheterization. The book also describes the author's role as the lead person in establishing the Dotter Interventional Institute in 1990. The Institute was the first freestanding, independent interventional radiology unit to deal with education, research, and patient care. Dr. Rösch's organization of scientific meetings and his early use of techniques for live internet broadcasting are described, and the book concludes by summarizing the multiple honors and awards that he received in recognition of his achievements.
  • 2011 Springer
    Debra A. Gervais, Tarun Sabharwal (editors).
    General principles of biopsy and drainage -- Liver biopsy -- Chest biopsy -- Mediastinal biopsy -- Bone biopsy -- Adrenal biopsy -- Renal biopsy -- Pancreatic biopsy -- Lymph node biopsy -- Splenic biopsy -- Thyroid biopsy -- Prostate biopsy -- Drainage of abdominal fluid collections -- Drainage of pelvic fluid collections -- Drainage of intrathoracic fluid collections -- Liver cyst/abscess drainage -- Drainage of pancreatic abscess and fluid collections -- Percutaneous biliary drainage and stenting -- Percutaneous cholecystostomy and cholecystolithotomy -- Percutaneous nephrostomy and antegrade ureteric stenting -- Fluoroscopy-guided percutaneous renal access for treatment of stone disease -- Percutaneous gastrostomy and gastrojejunostomy.
  • Ferral, Hector; Lorenz, Jonathan.
    Status: Not Checked OutLane Catalog Record
  • 2013 Springer
    Timothy Clark, Tarun Sabharwal editors.
    The Techniques in Interventional Radiology series of handbooks describes in detail the various interventional radiology procedures and therapies that are in current practice.The series comprises a number of titles, which cover procedures in angioplasty and stenting, transcatheter embolization and therapy, biopsy and drainage, ablation, pediatric interventional radiology and neurointerventional radiology. Each book is laid out in bullet point format, so that the desired information can be located quickly and easily. Interventional radiologists at all stages, from trainees through to specialists, will find this book a valuable asset for their practice.Interventional Radiology Techniques in Ablation is a practical and concise guide to contemporary techniques in image-guided tumor ablation. This handbook is intended to serve as a quick reference for physicians in interventional radiology training as well as a resource for IR technologists, nurses, nurse practitioners and physician assistants.
  • 2008 ClinicalKey
    editors, Curtis W. Slipman [and others] ; associate editors, Larry H. Chou [and others].
    As many as 80% of patients will suffer from back pain at some point in their lifetime. It is the most common form of disability, and the second largest cause of work absenteeism. An early, proactive management approach offers the best route to minimizing these conditions. Renowned authority Curtis W. Slipman, MD and a team of multidisciplinary authorities present you with expert guidance on today's best non-surgical management methods, equipping you with the knowledge you need to offer your patients optimal pain relief. Refresh your knowledge of the basic principles that must be understood before patients with spinal pain can be properly treated. Know what to do when first-line tests and therapies fail, using practice-proven diagnostic and therapeutic algorithms. Offer your patients a full range of non-surgical treatment options, including pharmacology, physical therapy, injection techniques, ablative procedures, and percutaneous disc decompression. Make an informed surgical referral with guidance on indications, contraindications, methods, and postoperative rehabilitation. Better understand key techniques and procedures with visual guidance from more than 500 detailed illustrations. Download all of the book's illustrations from the accompanying CD-ROM for use in electronic presentations.
  • 2013 Thieme Book
    edited by Olav Jansen, Hartmut Brückmann.
    Internal carotid artery occlusion / O. Jansen -- Middle cerebral artery occlusion / C. Reidel -- Vertebrobasilar occlusion / D. Morhard and G. Schulte-Altedorneburg -- Dissections / T. Boeckh-Behrens -- Cerebral venous and sinus thrombosis / J. Linn -- Thrombolysis : intravenous thrombolysis / G. F. Hamann -- Intra-arterial thrombolysis / B. Eckert -- Mechanical recanalization materials : aspiration thrombectomy -- A. Kreusch and M. Knauth -- Temporary stenting in stroke patients / J. Klisch -- Retrievers and other thrombectomy systems / T. Struffert and A. Dörfler -- Treatment concepts and results : carotid-T occlusion / G. Fesl -- Occlusion of the middle cerebral artery / T. Liebig -- Basilar artery thrombosis / G. Schulte-Altedorneburg and H. Brückmann -- Cervical artery dissections / A. Rohr and H. Görike -- Treatment of acute cerebral venous occlusions / T. E. Mayer -- Equipment : stents, filters, and balloon systems / M. Holtmannspötter -- Extracranial carotid stenoses / M. Tietke and O. Jansen -- Intracranial stenoses / W. Kurre -- Subclavian steal syndrome / A. Berlis -- Proximal vertebral artery stenosis / N. Lummel and H. Brückmann -- Proximal stenosis of supra-aortic vessels / J. Berkefeld.
  • 2009 Springer
    Reynolds Delgado, editor ; Harvinder Singh Arora, associate editor.
  • 2015 Thieme Book
    [edited by] Christoph F. Dietrich, Dieter Nuernberg.
    General aspects of interventional ultrasound. Interventional ultrasound: introduction and historical background -- Interventional materials and equipment -- Informed consent -- Medications, equipment, and setup requirements -- Pathology and cytology -- Fine needle aspiration cytology -- Infections and diganostic microbiology -- Hygiene management -- Contraindications, complications, and complication management -- Assistance in ultrasound interventions -- Sedation in interventions -- Specifc ultrasound-guided procedures: abdomen. Indications for diagnostic interveions in the abdomen and thorax (liver, pancreas, spleen, kidneys, lung, other sites) -- Diagnostic and therapeutic paracentesis of free abdominal fluid -- Fine needle aspiration biopsy and core needle biopsy -- Abscess drainage -- Percutaneous sclerotherapy of cysts -- Interventional treatment of echinococcosis -- Local ablative procedures: percutaneous ethanol and acetic acid injection -- Local ablative procedures for liver tumors, radiofrequency ablation -- Percutaneous transhepatic cholangiodrainage -- Percutaneous gastrostomy -- Interventional endosonography -- Special issues regarding interventions in the spleen -- Specific ultrasound-guided procedures: thorax. Thoracic interventions -- Specific ultrasound-guided procedures: urogenital system. Percutaneous renal biopsy -- Interventional urology -- Specific ultrasound -guided procedures: other organ systems. Interventional thyroid ultrasound -- Musculskeletal interventions -- Neurologic interventions, ultrasound-guided regional anesthesia -- Utlrasound-guided emergency and vascular interventions -- Specific ultrasound-guided procedures: other applications of interventional ultrasound. Extravascular use of ultrasound contrast agents -- Volume navigation -- Palliative interventions and the role of ultrasonography in palliative care.
  • 2016 Springer
    Ardeshir R. Rastinehad, David N. Siegel, editors ; Peter A. Pinto, Bradford J. Wood, associate editors.
    History of Invasive Radiology -- Imaging the Urinary Tract: Fundamentals of Ultrasound, Computed Tomography, and Magnetic Resonance Imaging -- Image Fusion Principles: Theory -- Prostate Imaging -- Imaging of Benign Prostatic Conditions -- Transrectal Ultrasound of the Prostate -- Fusion Guided Prostate Biopsy -- Template Mapping Biopsies: An Overview of Technique and Results -- Contrast-Enhanced Ultrasound (CEUS) and Elastographic imaging -- High Intensity Focused Ultrasound for Prostate Cancer -- Laser Interstitial Thermal Therapy -- IRE for Prostate Cancer -- Cryotherapy for Prostate Cancer -- Radiation Therapy: Brachytherapy -- Selective Arterial Prostatic Embolization (SAPE) -- BPH Embolization -- Treatments for Benign Conditions of the Prostate Gland -- Kidney Imaging -- Renal Mass Biopsy -- Urinary Diversion and Drainage -- Renal Ablations -- Renal Angiography and Embolization -- Nutcracker Syndrome -- Renal Artery Stenosis -- Hemorrhagic Cystitis -- Endovascular Management of Priapism and Erectile Dysfunction -- Adrenal Imaging -- Adrenal Interventions -- Varicocele and Pelvic Congestion Syndrome -- Retroperitoneal Biopsy: Indications and Imaging Approach.
  • 2005 Springer
    M. Obladen (editor), P. Koehne (editor).
  • 2013 Springer
    Jose Pablo Díaz-Jimenez, Alicia N. Rodriguez, editors.
    Interventions in Pulmonary Medicine is an important new volume that addresses all areas of interventional pulmonology, a minimally invasive endoscopic way to diagnose and treat lung disorders. This volume contains dedicated chapters that outline the many issues related to lung cancer, both in early and advanced stages, from diagnosis to personalized treatment. It also covers bronchoscopic therapeutic options to benign conditions that are highly prevalent, such as COPD and asthma. Techniques described in this volume are: laser therapy, argon plasma coagulation therapy, cryotherapy, brachytherapy, placement of intrapleural drainage systems, endoscopic treatment of emphysema, stents in the airway, and thermoplasty for bronchial asthma. Diagnostic procedures that are covered are: medical thoracoscopy, flexible and rigid bronchoscopy, endobronchial ultrasound, electromagnetical navigation, and trends in personalized treatment for lung cancer and other benign lung conditions. Chapters are written by experts and the developers of the techniques that are currently considered gold standard. Evidence-based reviews are presented for all topics and indications, and contraindications are discussed. Interventions in Pulmonary Medicine is a must have for pulmonologists, endoscopists, pulmonary oncologists, ENT physicians, thoracic surgeons, anesthesiologists, and intensive care specialists and their teams.
  • 2014 Springer
    Irving M. Shapiro, Makarand V. Risbud, editors.
    The intervertebral disc is composed of a complex tissue that separates neighboring vertebrae, permits a wide range of motion, and cushions the high biomechanical forces on the spine. Disc degeneration leads to a loss of function and is often associated with excruciating pain. Written by leading scientists and clinicians, this is the only book in the past fifty years devoted entirely to the study of the intervertebral disc. The first part of the book provides a review of the basic biology of the disc in health and disease. The second part considers strategies for mitigating the effects of disc degeneration and discusses the possibility of engineering replacement tissues. The final section is dedicated to approaches that model normal development, and the elucidation of the pathogenesis of degenerative disc disease using animal, organ and cell culture techniques. This unique and authoritative book bridges the gap between the basic and clinical sciences; its target audience includes basic scientists, orthopedists, neurologists, rehabilitation and physical therapists, primary care physicians and chiropractors, while it also addresses the needs of graduate students, medical students, interns, fellows, and patients who suffer from disc-related pathologies.
  • 2009 Thieme eNeurosurgery
    Juergen Kraemer ; with contributions by Monika Hasenbring [and others] ; translated by Ethan Taub ; illustrators, Christiane and Michael von Solodkoff.
  • v.1-2., 2006
    interviewer and editor, Nancy M. Rockafellar.
    Status: Not Checked OutLane Catalog Record
  • 2005 CRCnetBASE
    edited by Laura E. Matarese, Ezra Steiger, Douglas L. Seidner.
  • 2014 CRCnetBASE
    editors, Eduardo J. Schiffrin, Philippe Marteau, Dominique Brassart.
    1. Commensal intestinal microbiota and mucosal immune system development and function / Katarina Radulovic and Jan Hendrik Niess -- 2. Presentation of microbial signals via maternal cells : an evolutionary advantage of mammals / Pablo F. Perez, Anne Donnet-Hughes and Eduardo J. Schiffrin -- 3. Interactions of the intestinal microbiota with mucosal epithelial cells / Cherbuy Claire, Tomas Julie, Thomas Muriel and Langella Philippe -- 4. Pathogen-host cell interactions at the intestinal level : 88 lessons from cultured human fully-differentiated colon cancer Caco-2 and T84 epithelial cell lines / Vanessa Liv̌in-Le Moal and Alain L. Servin -- 5. Manipulation of the host-cell pathways by bacterial enteropathogens / Brice Sperandio and Philippe J. Sansonetti -- 6. The role of probiotics in prevention and treatment of GI infections / Christina M. Surawicz and Christopher Damman -- 7. The microbiota in inflammatory bowel disease / Philippe Marteau, Marion Leclerc, Patricia Lepage, Philippe Seksik, Harry Sokol and Joel Dor ̌-- 8. Opportunistic pathogens in inflammatory bowel disease, and the relation with specific gene susceptibilities / Marianne Fraher and Fergus Shanahan -- 9. Opportunistic pathogens in inflammatory bowel disease, the case of adherent-invasive e. coli / Arlette Darfeuille-Michaud -- 10. Correction of microbiota disturbances or antagonism against specific pathogens in IBD / Paul K. Flanagan and Jonathan M. Rhodes -- 11. Probiotics in inflammatory bowel disease : modulation of the pathological immune or inflammatory activation. Their potential benefits in the different phases of the disease / Siew C. Ng and Ailsa L. Hart -- 12. Mechanisms, prevention and management of diarrhoea in enteral nutrition / Kevin Whelan and Stp̌hane M. Schneider -- 13. Influence of the intestinal microbiota on the critically ill patient / Robert G. Martindale, Stephen A. McClave, Malissa Warren and Svetang Desai -- 14. Gut microbiota in obesity and Type-2 diabetes : links with diet and weight loss intervention / Judith Aron-Wisnewsky and Karine Clm̌ent.
  • 2006 Springer
    Helmut König, Ajit Varma (eds.).
  • 2016 Springer
    Lisa A. Boardman, editor.
    1. The intestinal polyposes: clinical and molecular overview -- 2. MUTYH-associated polyposis -- 3. Inflammatory "cap" polyposis -- 4. Serrated polyposis syndrome -- 5. Polymerase proofreading associated polyposis, and other new syndromes of hereditary colorectal cancer -- 6. Juvenile polyposis syndrome -- 7. PTEN hamartoma tumor syndrome -- 8. Cronkhite-Canada Syndrome -- 9. Peutz-Jeghers Syndrome -- 10. Hereditary mixed polyposis syndrome -- 11. Familial adenomatous polyposis -- Index.
  • 2009 Springer
    G.G. Delaini, T. Skr̆ic̆ka, G. Colucci, editors ; foreword by John Nicholls.
  • 2016
    James R. Doty, MD.
    Status: Not Checked OutLane Catalog Record
    The author relates how a chance encounter in a magic shop with a woman who taught him exercises to ease his sufferings and manifest his greatest desires gave him a glimpse of the relationship between the brain and the heart, and drove him to explore the neuroscience of compassion and altruism.
  • 2004 NCBI Bookshelf
    [edited by Joel G. Breman, Martin S. Alilio, and Anne Mills].
  • 2013 Cambridge
    Manu Malbrain, Jan De Waele.
  • 2006
    editor, Andrea Natale ; co-editors, David J. Wilber ... [et al.].
    Status: Not Checked OutLane Catalog Record
    Introduction -- Atrial chambers: gross anatomy and intracardiac phased-array echocardiography imaging -- Interatrial septum -- Role of intracardiac echocardiography for ablation of ventricular tachycardia -- Abnormal anatomy: left atrial structures -- Intracardiac echocardiography during catheter ablation for atrial fibrillation -- Transcatheter occlusion of left atrial appendage for stroke prevention in atrial fibrillation--potential role for intracardiac echocardiography -- Intracardiac echocardiography: transseptal catheterization -- Right atrium: ICE in anatomic definition, mapping and ablation -- Intracardiac echocardiography in the congenital catheterization laboratory -- Intrapericardial echocardiography: a novel catheter-based approach to cardiac imaging -- Three-dimensional echocardiography--future applications in interventional cardiology -- Future of image-guided therapies in interventional electrophysiology.
  • 2010
    Amin Nikoozadeh.
    Atrial fibrillation, the most common type of cardiac arrhythmia, now affects more than 2.2 million adults in the United States alone. Currently, electrophysiological interventions are performed under fluoroscopic guidance, which does not provide adequate soft-tissue resolution and exposes the patient and the operator to harmful ionizing radiation. Intracardiac echocardiography (ICE) provides real-time anatomical information that has proven valuable in reducing the fluoroscopy time and enhancing procedural success. This dissertation describes the design and implementation of two types of multi-functional, forward-looking ICE catheters developed using capacitive micromachined ultrasonic transducer (CMUT) technology: MicroLinear (ML) and Ring catheters. The ML catheter enables real-time, forward-looking 2D imaging using a 24-element, fine-pitch 1D CMUT phased array. The Ring catheter uses a 64-element, ring-shaped 2D CMUT array that enables real-time, forward-looking, volumetric imaging. Both of these catheters are equipped with custom-designed, front-end electronic circuits that are integrated with each transducer array at the catheter tip. The close integration of custom electronic circuits with the ML and Ring CMUT arrays improves the signal-to-noise ratio (SNR) in each case by 18 dB and 20dB, respectively. The integration process of the CMUT arrays with the electronics dice in the tight space available for full catheter construction shows 100% yield. The characterization of the fully-integrated CMUT arrays demonstrates excellent pulse-echo response with over 100% fractional bandwidth as well as surface transmit pressure levels in excess of 1 MPa (peak-to-peak). The first fully-functional 9F ML CMUT ICE catheter shows remarkable in vivo imaging performance using porcine animal models. A similar in vivo imaging experiment with the first fully-functional 12F Ring CMUT ICE catheter proves very promising. The volumetric imaging capability of the Ring ICE catheter and the versatility offered by its inner lumen make it an attractive interventional device. This dissertation also introduces a novel CMUT structure, called PCMUT. The preliminary simulation and experimental verification of the PCMUT structure show that it is possible to fabricate CMUTs that exhibit non-flexural piston-like plate motion with a significantly improved volume displacement and fill-factor.
  • 2011 Springer
    Aleš Prokop, editor.
  • 2007 Springer
    edited by Ivan de Curtis.
  • 2011 Springer
    edited by John Zhang, Austin Colohan.
    The volume includes 75 papers which were presented at the Third International Conference on Intracerebral Hemorrhage, held in Rancho Mirage, California, in March 2010. The topics treated include animal models, pathophysiology of cerebral hemorrhage, experimental treatment for cerebral hemorrhage, cerebral hemorrhage clinical manifestations, prognosis of cerebral hemorrhage, and clinical management. The articles represent the recent advances in hemorrhagic brain injury research presented by highly respected laboratories around the world.
  • 2012 Thieme eNeurosurgery
    Duke S. Samson [and others].
    "In the face of rapid development and impressive improvements in endovascular technology and techniques, there remain a large number of intracranial aneurysms for which microvascular surgery remains either the only or the preferable management option. Additionally, the complications of endovascular treatment have generated a unique subset of aneurysms requiring special surgical skills. Preparation to meet the challenges raised by all of these lesions begins with assimilation of basic aneurysm surgical techniques and the development of a conceptual framework for their use. The most reliable training ground for excellent microsurgical technique remains cerebrovascular disease in general and aneurysm surgery in specific. Furthermore, despite the wide-spread availability of lengthy texts that address all aspects of intracranial vascular pathologies, there seems to remain a persistent demand for nitty-gritty technical advice presented in a consistent, straight-forward, didactic format"--Provided by publisher.
  • 2008 Springer
    edited by G. Manley, C. Hemphill, S. Stiver.
  • 2012 Springer
    edited by M. U. Schuhmann, M. Czosnyka.
    Digitised ICP over Three Decades -- Latency Relationships Between Cerebral Blood Flow Velocity and Intracranial Pressure -- The Linear Relationship Between Transcranial Doppler Pulsatility Indices and Intracranial Pressure Is Influenced by Traumatic Brain Injury and Vasospasm -- Time Constant of the Cerebral Arterial Bed -- Pulse Amplitude and Lempel-Ziv Complexity of the Cerebrospinal Fluid Pressure Signal -- Association Between ICP Pulse Waveform Morphology and ICP B Waves -- Computerized Data Analysis of Neuromonitoring Parameters Identifies Patients with Reduced Cerebral Compliance as Seen on CT -- Early Warning of EUSIG-Defined Hypotensive Events Using a Bayesian Artificial Neural Network -- Trigger Characteristics of EUSIG-Defined Hypotensive Events -- Go Green! Reusing Brain Monitoring Data Containing Missing Values: A Feasibility Study with Traumatic Brain Injury Patients -- Investigation of the Relationship Between Transcranial Impedance and Intracranial Pressure -- Bioinformatics Analysis of Mortality Associated with Elevated Intracranial Pressure in Children -- A Versatile Software for Assessment of CSF Dynamics -- Modified Brainstem Auditory Evoked Responses in Patients with Non-brainstem Compressive Cerebral Lesions -- Analysis of Intracranial Pressure Time Series Using Wavelets (Haar Basis Functions) -- Stationarity in Neuromonitoring Data -- Is ICP Solid or Fluid? In Vitro Biomechanical Model Using a Fluid-Saturated Gel -- Implantable ICP Monitor for Improved Hydrocephalus Management -- Intracranial Pressure Telemetry: First Experience of an Experimental In Vivo Study Using a New Device -- Telemetric ICP Measurement with the First CE-Approved Device: Data from Animal Experiments and Initial Clinical Experiences -- The New ICP Minimally Invasive Method Shows That the Monro-Kellie Doctrine Is Not Valid -- Non-Invasively Estimated ICP Pulse Amplitude Strongly Correlates with Outcome After TBI. Realization of a Comprehensive Non-invasive Detection of Intracranial Pressure Analyzer Based upon FVEP and TCD -- Electrophysiological Monitoring of Cochlear Function as a Non-invasive Method to Assess Intracranial Pressure Variations -- Autoregulatory Model Comparison and Optimisation Methodology -- Assessment of Cerebral Autoregulation from Respiratory Oscillations in Ventilated Patients After Traumatic Brain Injury -- Monitoring of the Association Between Cerebral Blood Flow Velocity and Intracranial Pressure -- How Does Moderate Hypocapnia Affect Cerebral Autoregulation in Response to Changes in Perfusion Pressure in TBI Patients? -- Correlation of Clinical Outcome and Angiographic Vasospasm with the Dynamic Autoregulatory Response After Aneurysmal Subarachnoid Hemorrhage -- Comparison of a New Brain Tissue Oxygenation Probe with the Established Standard -- Comparing Brain Tissue Oxygen Measurements and Derived Autoregulation Parameters from Different Probes (Licox vs. Raumedic) -- Experimental Comparison of the Measurement Accuracy of the Licox® and Raumedic® Neurovent-PTO Brain Tissue Oxygen Monitors -- Is PbrO2 Pressure Reactivity Index (ORx) Dependent on the Type of Oxygen Probe? An In Vivo Study -- Continuous Quantitative Monitoring of Cerebral Oxygen Metabolism in Neonates by Ventilator-Gated Analysis of NIRS Recordings -- Near Infrared Spectroscopy as Possible Non-invasive Monitor of Slow Vasogenic ICP Waves -- Drift of the Bowman Hemedex® Cerebral Blood Flow Monitor Between Calibration Cycles -- Quantification of Pulsatile Cerebrospinal Fluid Flow within the Prepontine Cistern -- Delta-ADC (Apparent Diffusion Coefficient) Analysis in Patients with Idiopathic Normal Pressure Hydrocephalus -- Evidence for Altered Spinal Canal Compliance and Cerebral Venous Drainage in Untreated Idiopathic Intracranial Hypertension -- Automated Extraction of Decision Rules for Predicting Lumbar Drain Outcome by Analyzing Overnight Intracranial Pressure -- Lack of Correlation of Overnight Monitoring Data and Lumbar Infusion Data in iNPH Patients. Shunt-Dependent Hydrocephalus Following Subarachnoid Hemorrhage Correlates with Increased S100B Levels in Cerebrospinal Fluid and Serum -- Normal Hypocretin-1 (Orexin A) Levels in Cerebrospinal Fluid in Patients with Idiopathic Intracranial Hypertension -- Frontal and Temporal Horn Ratio: A Valid and Reliable Index to Determine Ventricular Size in Paediatric Hydrocephalus Patients? -- Intraventricular Cooling During CSF Infusion Studies -- An Uncommon Case of Idiopathic Intracranial Hypertension with Diagnostic Pitfalls -- Micro-fabricated Shunt to Mimic Arachnoid Granulations for the Treatment of Communicating Hydrocephalus -- On the Method of a Randomised Comparison of Programmable Valves with and Without Gravitational Units: The SVASONA Study -- Idiopathic Normal Pressure Hydrocephalus: Results of a Prospective Cohort of 236 Shunted Patients -- Idiopathic Normal Pressure Hydrocephalus (iNPH) and Co-Morbidity: An Outcome Analysis of 134 Patients -- Intracranial Pressure Measurement in Infants Presenting with Progressive Macrocephaly and Enlarged Subarachnoid Spaces -- Treatment Options for Intracranial Arachnoid Cysts: A Retrospective Study of 69 Patients -- A Microdialysis Study of Oral Vigabatrin Administration in Head Injury Patients: Preliminary Evaluation of Multimodality Monitoring -- The Atrial Natriuretic Peptide Does Not Serve Osmoregulation but Predicts Outcome Following Brain Injury -- Bedside Study of Cerebral Critical Closing Pressure in Patients with Severe Traumatic Brain Injury: A Transcranial Doppler Study -- Traumatic Brain Injury in the Elderly: A Significant Phenomenon -- Fixed, Dilated Pupils Following Traumatic Brain Injury: Historical Perspectives, Causes and Ophthalmological Sequelae -- Why Mortality Is Still High with Modern Care of 613 Evacuated Mass Lesions Presented as Severe Head Injuries 1999-2009 -- Late Decompressive Craniectomy as Rescue Treatment for Refractory High Intracranial Pressure in Children and Adults -- CT Angiography as a Confirmatory Test in Brain Death. The Imaging Diagnosis and Prognosis Assessment of Patients with Midbrain Injury in the Acute Phase of Craniocerebral Injury -- The Effect of Intraventricular Thrombolysis in Combination with Low-Frequency Head Motion After Severe Subarachnoid Hemorrhage: Interim Analysis of Safety, Clot Clearance Rate and Delayed Cerebral Ischemia -- Early CT Perfusion Measurement After Aneurysmal Subarachnoid Hemorrhage: A Screening Method to Predict Outcome? -- Cerebrospinal Fluid Lactate Concentration After Withdrawal of Metabolic Suppressive Therapy in Subarachnoid Hemorrhage -- Effect of Increased ICP and Decreased CPP on DND and Outcome in ASAH -- Prior Statin Use Has No Effect on Survival After Intracerebral Hemorrhage in a Multiethnic Asian Patient Cohort -- The Impact of Silver Nanoparticle-Coated and Antibiotic-Impregnated External Ventricular Drainage Catheters on the Risk of Infections: A Clinical Comparison of 95 Patients -- Dependence of Cerebrospinal Fluid Pressure and Volume on the Changes in Serum Osmolarity in Cats -- The Effect of Body Position on Intraocular and CSF Pressures in the Lateral Ventricle, and in Cortical and Lumbar Subarachnoid Spaces in Cats -- Pressure Reactivity Index Correlates with Metabolic Dysfunction in a Porcine Model of Intracerebral Hemorrhage -- Evidence of Spreading Depolarizations in a Porcine Cortical Intracerebral Hemorrhage Model -- Spontaneous Cortical Spreading Depression and Intracranial Pressure Following Acute Subdural Hematoma in a Rat -- The Peptide AF-16 and the AF Protein Counteract Intracranial Hypertension -- Influence of Isoflurane on Neuronal Death and Outcome in a Rat Model of Traumatic Brain Injury -- Correlation of the Intracranial Pressure to the Central Venous Pressure in the Late Phase of Acute Liver Failure in a Porcine Model -- Visualisation of Cortical pO2 During an Epidural Mass Lesion in Rodents -- Development of an Experimental Model to Study the Pathophysiology of Cerebral Salt Wasting Following Subarachnoid Hemorrhage.
  • 2016 Springer
    Beng-Ti Ang, editor.
  • 2015 Thieme-Connect
    [edited by] L. Dade Lunsford, Jason P. Sheehan.
  • 2009 Thieme eNeurosurgery
    [edited by] L. Dade Lunsford, Jason P. Sheehan.
    Stereotactic radiosurgery from notion to practice / Erik-Olof Backlund -- Radiobiology of stereoatactic radiosurgery / John C. Flickinger -- How brain tumors respond to stereoatactic radiosurgery / György T. Szeifert ... [et al.] -- Image-guided stereoatactic radiosurgery / Jasvinder Nangiana, John R. Adler Jr., and Steven D. Chang -- Stereoatactic radiosurgery for arteriovenous malformations / L. Dade Lunsford ... [et al.] -- Stereoatactic radiosurgery for dural arteriovenous fistulas / Michael Söderman ... [et al.] -- Stereoatactic radiosurgery for cavernomas / Bengt Karlsson and Michael Söderman -- Stereoatactic radiosurgery for meningiomas / Douglas Kondziolka ... [et al.] -- Stereoatactic radiosurgery for pituitary adenomas / Jay Jagannathan ... [et al.] -- Stereoatactic radiosurgery for skull base chordomas and chondrosarcomas / Jean-Louis Habrand ... [et al.] -- Stereoatactic radiosurgery for glomus tumors / Jeffrey T. Jacob ... [et al.] -- Stereoatactic radiosurgery for vestibular schwannomas / Nicholas Massager and Marc Levivier -- Stereoatactic radiosurgery for nonvestibular schwannomas / Ajay Niranjan ... [et al.] -- Stereoatactic radiosurgery for trigeminal neuralgia / Jean Régis ... [et al.] -- Stereoatactic radiosurgery for movement disorders / Joel Bauman and John Y.K. Lee -- Stereoatactic radiosurgery for epilepsy / Mark Quigg and Nicholas M. Barbaro -- Stereoatactic radiosurgery for ocular disorders / Roman Lis̆c̆ák and Gabriela Śimonová -- Stereoatactic radiosurgery for gliomas / Gregory J.A. Murad and William A. Friedman -- Stereoatactic radiosurgery for brain metastases / Mayur Jayarao, Lawrence S. Chin, and William F. Regine -- Stereoatactic radiosurgery for pediatric brain tumors / Simon S. Lo, Gene H. Barnett, and John H. Suh.
  • 2005 Springer
    edited by M. Forsting ; foreword by K. Sartor.
  • 2008 Springer
    M. Forsting, I. Wanke., eds. ; with contributions by C. Cognard ... [et al.] ; foreword by M. Knauth.
  • 2006
    editor Warren T. Blume ; associate editors, Peter L. Carlen ... [et al.].
  • 2012 Springer
    Marcel B.M. Teunissen, editor.
    Understanding the murine cutaneous dendritic cell network to improve intradermal vaccination strategies -- Insight into the immunobiology of human skin and functional specialization of skin dendritic cell subsets to innovate intradermal vaccination design -- Delivery systems for intradermal vaccination -- Targeting skin dendritic cells to improve intradermal vaccination -- Intradermal rabies vaccination : the evolution and future of pre- and post-exposure prophylaxis -- Intradermal vaccination to protect against yellow fever and influenza -- The dermis as a portal for dendritic cell-targeted immunotherapy of cutaneous melanoma -- DNA vaccines and intradermal vaccination by DNA tattooing
  • 2014 Springer
    Masao Tanaka, editor.
    Intraductal papillary mucinous neoplasms (IPMNs) represent an opportunity to treat pancreatic tumors before they develop into aggressive, hard-to-treat cancers. Beginning with morphological classification and its clinical significance, natural history, and malignant change of both main duct and branch duct IPMNs, this book covers the whole field of IPMNs of the pancreas. It reviews the various methods of investigation: imaging, diagnostic investigation of cyst fluid, and those using pancreatic juice; and also examines aspects ranging from the development of malignancy to the timing and method of resection, focusing on both main duct and branch duct IPMNs. Aimed at residents, clinical fellows, and pancreatologists who treat patients with this common disease of the pancreas, this book is a landmark in the current understanding and future perspectives of IPMNs of the pancreas.
  • 2009 Springer
    Maode Lai, editor.
  • 2015 Springer
    Pol M. Rommens, Martin H. Hessmann, editors.
    This book provides fundamental and practical knowledge in the treatment of fractures, healing disturbances and bone disorders with intramedullary nailing. It comprehensively discusses this biological and mechanical technique for appropriate indications and aims to ameliorate the standard of care for those patients who can benefit from intramedullary nailing. Its purpose is to guide the readers on the ?why, when, and how? for intramedullary nailing and is the first comprehensive resource to cover the actual know-how of this technique. Intramedullary Nailing: A Comprehensive Guide brings together a large number of experts and opinion leaders in the field of operative fracture care and reconstructive surgery to share their extensive experience with the readership of this book. Orthopedic trauma surgeons from all over the world, who work in many different circumstances and with the most diverse technical and logistical equipment, will find this book to be an essential resource and guide for utilizing this technique in clinical practice.
  • 2007 Springer
    edited by Nigel M. Hooper and Uwe Lendeckel.
    Site-2 protease at ten -- Signal peptide peptidases -- GXGD-type intramembrane proteases -- Rhomboid intramembrane serine proteases -- Proteases of the Rhomboid family in the yeast Saccharomyces cerevisiae -- [gamma]-Secretase and Alzheimer's disease -- [gamma]-Secretase mediated proteolysis: at the cutting edge of notch signaling.
  • 2016 Springer
    edited by Manfred Zierhut ... [and others].
    Anatomy -- Classification and Terminology -- Immunology and Experimental Uveitis -- Epidemiology -- Evaluation (History, Examination) -- Serology -- Fluorescence Angiography/Indocyanin Angiography -- Ocular Coherence Tomography -- Electrodiagnostic Tests -- Ultrasonography -- Ocular Biopsy -- Diagnostic Vitrectomy -- Laser Flare Photometry -- AC Diagnostics -- Diagnostic Imaging Procedures -- Genetics -- Uveitis and Clinical Trials -- Evidence Based Medicine -- General Considerations.- Corticosteroids -- Non-Steroidal Anti-Inflammatory Drugs -- Anti-TNF-alpha-Blocking Agents.- Azathioprine.- Chlorambucil.- Cyclophosphamide -- New Drugs -- Intraocular Drug Delivery.- Cataract.- Macular Edema.- Glaucoma -- Subretinal Fibrosis.- Vitrectomy -- Anterior Uveitis -- Intermediate Uveitis -- Posterior Uveitis -- White-Dot-Syndrom.- Panuveitis -- Retinal Vasculitis.- Retinitis -- Uveitis in Children.
  • 2016 Springer
    Thomas H. Williamson.
    Surgical Philosophy -- Finite Element Analysis (FEA), Material Properties and Tissue Geometry in Ophthalmology -- Surgical principles: Instruments -- Surgical Principles: Wounds and Tissue Manipulation -- Surgical Principles: Compartments -- Surgical Principles: Machines -- Surgical Principles: Fluids -- Surgical Principles: Microscopes, Light and Lasers -- Surgical Principles: Suturing. .
  • 2015 ClinicalKey
    [edited by] Alberto Marchevsky, Fadi W. Abdul-Karim, Bonnie Balzer.
    "When a patient is under anesthesia, every second counts. An intraoperative consultation provides essential information to ensure every operation has a successful conclusion. The stakes are high and the challenges are great -- no special stains, limited access for consultation with colleagues, often suboptimal slide preparation, and cases that may be out of a pathologist's normal sphere of practice. Diagnostic Pathology: Intraoperative Consultation is designed to be the best resource when pathologists need assistance. No time is wasted looking for information because each chapter is directed to a specific question posed by a surgeon, such as 'Does this patient have pancreatic cancer?', 'Is there an intrauterine pregnancy?', 'Does this patient have lung cancer?', or 'Are the margins free of carcinoma?' The clinical setting and what the surgeon needs to know -- and why -- are explained. Specimen processing (gross and microscopic), tissue selection, and reporting of results are detailed. All major entities in the differential diagnosis are described and shown in photographs. Major pitfalls are discussed and illustrated. This is the book every pathologist will want at their side the next time a page calls them to the frozen section room"--Provided by publisher.
  • 2012 ClinicalKey
    [edited by] Donald C. Oxorn.
    Intraoperative Echocardiography - a volume in the exciting new Practical Echocardiography Series edited by Dr. Catherine M. Otto -provides practical, how-to guidance on intraoperative echocardiography in adult and pediatric patients. Definitive, expert instruction from Dr. Donald C. Oxorn is presented in a highly visual, case-based approach that facilitates understanding and equips you to master this difficult technique while overcoming the unique challenges and risks it presents. Master challenging and advanced intraoperative echocardiography techniques such as epiaortic echocardiography and 3-D echocardiography through a practical, step-by-step format that provides a practical approach to image acquisition and analysis, technical details, pitfalls, and case examples. Reference the information you need quickly thanks to easy-to-follow, templated chapters, with an abundance of figures and tables that facilitate visual learning. Become an expert in echocardiographic evaluation of complex valvular heart disease, congenital heart disease, and intravascular devices in patients undergoing cardiac surgery and interventional cardiology procedures.
  • 2011 Springer
    edited by M. Necmettin Pamir, Volker Seifert, Talat Kiriş.
    From vision to reality: the origins of intraoperative MR imaging -- Development of intraoperative MRI: a personal journey -- Lows and highs: 15 years of development in intraoperative magnetic resonance imaging -- Intraoperative imaging in neurosurgery: where will the future take us? -- Development and design of low field compact intraoperative MRI for standard operating room -- Low field intraoperative MRI in glioma surgery -- Intraoperative MRI (ioMRI) in the setting of awake craniotomies for supratentorial glioma resection -- Glioma extent of resection and ultra-low-field iMRI: interim analysis of a prospective randomized trial -- Impact of a low-field intraoperative MRI on the surgical results for high-grade gliomas -- Intraoperative MRI and functional mapping -- Information-guided surgical management of gliomas using low-field-strength intraoperative MRI -- Implementation of the ultra low field intraoperative MRI PoleStar N20 during resection control of pituitary adenomas -- Intraoperative MRI for stereotactic biopsy -- The evolution of iMRI utilization for pediatric neurosurgery: a single center experience -- Implementation and preliminary clinical experience with the use of ceiling mounted mobile high field intraoperative magnetic resonance imaging between two operating rooms -- High-field iMRI in glioblastoma surgery: improvement of resection radicality and survival for the patient? -- Image guided aneurysm surgery in a Brainsuite ioMRI Miyabi 1.5 T environment -- From intraoperative angiography to advanced intraoperative imaging: the Geneva experience -- Intraoperative magnetic resonance imaging -- 3 T ioMRI: the Istanbul experience -- Intraoperative 3.0 T magnetic resonance imaging using a dual-independent room: long-term evaluation of time-cost, problems, and learning-curve effect -- Multifunctional surgical suite (MFSS) with 3.0 T iMRI: 17 months of experience -- Intraoperative MRI at 3.0 Tesla: a movable magnet -- One year experience with 3.0 T intraoperative MRI in pituitary surgery -- Intraoperative computed tomography -- Intraoperative CT in spine surgery -- O-arm guided balloon kyphaplasty: preliminary experience of 16 consecutive patients -- Intraoperative imaging with 3D ultrasound in neurosurgery -- Intraoperative 3-dimensional ultrasound for resection control during brain tumor removal: preliminary results of a prospective randomized study -- Advantages and limitations of intraoperative 3D ultrasound in neurosurgery: technical note -- Integrated intraoperative room design -- Multimodal navigation integrated with imaging -- Multimodality imaging suite: neo-futuristic diagnostic imaging operating suite marks a significant milestone for innovation in medical technology -- Improving patient safety in the intraoperative MRI suite suing an on-duty safety nurse, safety manual and checklist -- Operating room integration and telehealth -- Intraoperative robotics: NeuroArm -- Clinical requirements and possible applications of robot assisted endoscopy in skull base and sinus surgery -- Robotic technology in spine surgery: current applications and future developments -- Microscope integrated indocyanine green video-angiography in cerebrovascular surgery -- Application of intraoperative indocyanine green angiography for CNS tumors: results on the first 100 cases -- A technical description of the brain tumor window model: an in vivo model for the evaluation of intraoperative contrast agents.
    Also available: Print – 2011
  • 2014 Springer
    Ferenc A. Jolesz, editor.
    Image-guided therapy (IGT) uses imaging to improve the localization and targeting of diseased tissue and to monitor and control treatments. During the past decade, image-guided surgeries and image-guided minimally invasive interventions have emerged as advances that can be used in place of traditional invasive approaches. Advanced imaging technologies such as magnetic resonance imaging (MRI), computed tomography (CT), and positron emission tomography (PET) entered into operating rooms and interventional suites to complement already-available routine imaging devices like X-ray and ultrasound. At the same time, navigational tools, computer-assisted surgery devices, and image-guided robots also became part of the revolution in interventional radiology suites and the operating room. Intraoperative Imaging and Image-Guided Therapy explores the fundamental, technical, and clinical aspects of state-of the-art image-guided therapies. It presents the basic concepts of image guidance, the technologies involved in therapy delivery, and the special requirements for the design and construction of image-guided operating rooms and interventional suites. It also covers future developments such as molecular imaging-guided surgeries and novel innovative therapies like MRI-guided focused ultrasound surgery. IGT is a multidisciplinary and multimodality field in which teams of physicians, nurses, and other professionals, such as physicists, engineers, and computer scientists, collaborate in performing these interventions, an approach that is reflected in the organization of the book. Contributing authors include members of the National Center of Image-Guided Therapy program at Brigham and Womens Hospital and international leaders in the field of IGT.
  • 2011 Springer
    edited by Leonard L. Gunderson, Christopher G. Willett, Felipe A. Calvo, Louis B. Harrison.
    General rationale and historical perspective -- Rationale and historical perspective of intraoperative irradiation -- Biology of large dose per fraction irradiation -- Methods and techniques of treatment -- Intraoperative electron beam irradiation: physics and techniques -- HDR-IORT: physics and techniques -- Electronic brachytherapy/low KV-IORT: physics and techniques -- IORT with electron-beam, high-dose-rate brachytherapy or low-KV/electronic brachytherapy: methodological comparisons -- Normal tissue tolerance: IORT -- Normal-tissue tolerance to IOERT, EBRT, or both: animal and clinical studies -- Results of IORT alone or plus EBRT by disease site -- Central nervous system tumors -- Head and neck cancer -- Breast cancer -- Lung cancer -- Gastric cancer -- Pancreas cancer -- Bile duct and gallbladder cancer -- Primary colorectal cancer -- Recurrent colorectal cancer -- Retroperitoneal sarcomas -- Extremity and trunk soft-tissue sarcomas -- Bone sarcomas -- Gynecologic malignancies -- Genitourinary cancer -- Pediatric malignancies -- Conclusions and future possibilities -- Conclusions and future possibilities: IORT.
  • 2011 Thieme eNeurosurgery
    [edited by] Walter A. Hall, Christopher Nimsky, Charles L. Truwit.
    "Intraoperative MR-Guided Neurosurgery contains detailed coverage of this state-of-the-art technology from the pioneers who developed it. World-renowned neurosurgeons and neuroradiologists combine their collective wisdom and experience to demonstrate how MR-guided neuronavigation can be used to view real-time images of a patient's brain during surgery to help remove tumors with greater precision. The authors provide step-by-step descriptions of how to perform procedures, including advice based on their clinical results. Readers will learn about the advantages and drawbacks of the various MR imaging systems, clinical indications for MR-guidance, anesthesia considerations, safety concerns related to working in a magnetic environment, and much more"--Provided by publisher.
  • 2012 Springer
    Cynthia T. Welsh, editor.
    This volume acquaints the non-neuropathologist with the advantages of clinical-radiologic-pathologic correlation in neuropathology specimens, particularly in the intra-operative environment. This volume covers the enormous and sometimes insurmountable artifacts involed with freezing tissue, especially central nervous system tissue and how a good cytology preparation can add to, or even supply in isolation, a diagnosis. The text presents how to perform, and stain the cytologic preparations, and how to interpret them. The advantages and disadvantages of both frozen sections and cytologic preparations of various kinds are discussed. The presentation and format is very visual with diagrams, tables (including pearls and pitfalls), and many figures (therefore easy reading).An introductory chapter presents the pros and cons of supplemental cytology, the advantages and disadvantages of frozen sections, and the artifacts in both. Also included is an argument for knowing what the scans reveal and the impact of relevant patient history. The volume uses a case-based approach to show correlation between scan, history, frozen section and cytologic preparations.With the combination of extensive correlation of scans, cytology and frozen section with differential diagnosis, and analysis of the information crucial to the neurosurgeon in a case-based approach and with a special chapter written by a neuroradiologist, this volume is unique in presentation and utility and will be of great value to the trainee in pathology (residents/fellows), and practicing pathologists who include neuropathology in their practice, but do not have formal fellowship training in neuropathology.
  • 2006 Springer
    Aage R. Møller.
  • 2011 Springer
    Aage R. Moller.
    Basis of intraoperative neurophysiological monitoring -- Generation of electrical activity in the nervous system and muscles -- Practical aspects of recording evoked activity from nerves, fiber tracts and nuclei -- Anatomy and physiology of sensory systems -- Monitoring somatosensory evoked potentials -- Monitoring auditory evoked potentials -- Monitoring visual evoked potentials -- Anatomy and physiology of motor systems -- Practical aspects of monitoring spinal motor systems -- Practical aspects of monitoring cranial motor nerves -- Anatomy and physiology of peripheral nerves -- Practical aspects of monitoring peripheral nerves -- Identification of specific neural tissue -- Intraoperative diagnosis and guidance in an operation -- Anesthesia and its constraints in monitoring motor and sensory systems -- General considerations about intraoperative neurophysiology and monitoring -- Equipment, recording techniques, and data analysis and stimulation -- Evaluating the benefits of intraoperative neurophysiological monitoring.
  • 2016 Springer
    Francesco Prada, Luigi Solbiati, Alberto Martegani, Francesco DiMeco, editors.
    General aspects: Clinical US, historical aspects -- US physics, basic principles and clinical application -- B-mode ultrasound: Ultrasound system set up and general semeiology -- Echographic brain semeiology and topographic anatomy according to surgical approaches -- Intraoperative findings in brain tumor surgery -- IOUS B-mode intra-operative findings in spinal lesions -- IOUS B-mode intra-operative findings in peripheral nerve pathologies -- Multimodal imaging in glioma surgery -- Doppler imaging: Basic principles and clinical application.- Intra-operative Ultrasound, Fusion imaging and Virtual Navigation: Virtual navigation and interventional procedures. Navigable ultrasound, 3D ultrasound and fusion imaging in neurosurgery -- Contrast enhanced ultrasound (CEUS): Basic principles, general application and future trends -- CEUS in neurosurgery -- Elastosonography: Ultrasound Elastography.
  • 2012 Springer
    Antonio Malvasi, editor.
    Clinical Evaluation of Labor and Intrapartum Sonography / Thomas Popowski, Patrick Rozenberg -- General Intrapartum Sonography Setup and Use in Labor / Miguel Angel Barber -- The Use of Two-Dimensional (2D) and Three-Dimensional (3D) Ultrasound in the First Stage of Labor / Ariel L. Zimerman -- Intrapartum Sonography and Labor Progression / Torbjørn Moe Eggebø -- Occiput Posterior Position and Intrapartum Sonography / Antonino F. Barbera -- Asynclitism: Clinical and Intrapartum Diagnosis in Labor / Antonino F. Barbera -- The Angle of Progression: An Objective Assessment of Fetal Head Descent in the Birth Canal / Antonino F. Barbera -- Head Rotation in Labor and Intrapartum Sonography Diagnosis with 2D and 3D / Tullio Ghi, Aly Youssef -- Intrapartum Translabial Ultrasound (ITU) to Assess Birth Progress / Boris Tutschek, Thorsten Braun -- Use of Cervical Length in Labor and Delivery / Sushma Potti -- Intrapartum Sonography and Clinical Risk Management / Andrea Tinelli, Sarah Gustapane -- New Technologies for Monitoring Labor Progress / Dan Farine -- Fetal Progression in Birth Canal: State of the Art / Anna Maria Dückelmann.
  • 2007 Springer
    edited by C. William Helm and Robert P. Edwards.
    Management of ovarian cancer : the theory / Maurie Markman -- Management of ovarian cancer : clinical trials / Maurie Markman -- A systematic review and meta-analysis of randomized trials / Kenneth Jaaback -- Immunobiology and intraperitoneal immunobiologics in ovarian cancer / Ralph S. Freedman -- Intraperitoneal chemotherapy : technique and complications / Joan L. Walker -- Hyperthermia and chemotherapy : the science / Roger A. Vertrees, Jeffrey M. Jordan, and Joseph B. Zwischenberger -- Hyperthermic intraperitoneal chemotherapy in nongynecologic cancers / Bing Yi, Jason M. Foster, and Brian W. Loggie -- Peritoneal carcinomatosis of colorectal origin / Frans A.N. Zoetmulder -- Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for ovarian cancer : experience in France / Olivier Glehen and Francois-Noel Gilly -- Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for ovarian cancer : world experience / C. William Helm -- Techniques of delivering hyperthermic intraperitoneal chemotherapy / Jesus Esquivel, Paul H. Sugarbaker, and C. William Helm -- Future directions in the delivery of hyperthermic intraperitoneal chemotherapy / Scott Richard and Robert P. Edwards.
  • 2010 Springer
    David S. Alberts, Mary C. Clouser, Lisa M. Hess (editors).
    Current chemotherapy of ovarian cancer -- Principles of intraperitoneal chemotherapy -- Intraperitoneal chemotherapy: phase III trials -- Criteria for using intraperitoneal (IP) chemotherapy for advanced ovarian cancer -- Selection and placement of intraperitoneal catheters for IP chemotherapy for ovarian cancer -- Selection of drugs for intraperitoneal chemotherapy for ovarian cancer -- Administration guidelines for intraperitoneal chemotherapy for ovarian cancer -- Novel drugs for intraperitoneal therapy for ovarian cancer -- Cytoreductive surgery and perioperative intraperitoneal chemotherapy: an ongoing research effort -- Health-related quality of life and patient-reported outcomes.
  • 2016 Springer
    Michael H. Picard, Jonathan J. Passeri, Jacob P. Dal-Bianco, editors.
    TEE-guided cardioversion -- Transcatheter aortic valve replacement -- ASD closure -- Closure of paravalvular leaks -- VSD closure -- Transcatheter repair of the mitral valve -- LA appendage closure -- Hypertrophic cardiomyopathy -- alcohol septal ablation -- Percutaneous mitral valvotomy -- Catheter based removal of intracardiac thrombus -- OCT/IVUS role in coronary interventions -- Retrieving embolized devices -- Role of imaging in mechanical circulatory support of the heart.
  • 2005 Springer
    Yuri P. Altukhov.
  • 2012 ClinicalKey
    volume editors, Sudhir Diwan, Asokumar Buvanendran.
    Section 1. General considerations -- section 2. Implant devices -- section 3. Evidence-based practice -- section 4. Intrathecal drug delivery systems for spasticity -- section 5. Future of intrathecal drug delivery systems.
  • 2015
    Intrauterine devices (IUDs) are one of the most effective forms of reversible contraception. IUDs, along with implants, are known as long-acting reversible contraception (LARCs) because they can be used to prevent pregnancy for several years. IUDs have been used in the U.S. for decades, but a safety controversy in the 1970s prompted the removal of all but one IUD from the U.S. market by 1986. The first new generation IUD was introduced to the U.S. market in 1988, following revised Food and Drug Administration (FDA) safety and manufacturing requirements. Recent controversies have focused on the mechanism of action of IUDs, the high upfront costs for the device, and variability in insurance coverage and access. This fact sheet reviews the various IUDs approved by the FDA, awareness, use, and availability of IUDs, and key issues in insurance coverage and financing of IUDs in the U.S.
  • 2015 Karger
    volume editors, Philip C. Calder, Dan L. Waitzberg, Berthold Koletzko.
    Introduction to fatty acids and lipids / Burdge, G.C., Calder, P.C. -- Fatty acids, lipid emulsions, and the immune and inflammatory systems / Miles, E.A., Calder, P.C. -- Importance of fatty acids in the perinatal period / Demmelmair, H., Koletzko, B. -- Commercial lipid emulsions and all-in-one mixtures for intravenous infusion : composition and physicochemical properties / Driscoll, D.F. -- In vivo handling and metabolism of lipid emulsions / Carpentier, Y.A., Deckelbaum, R.J. -- Parenteral lipids : safety aspects and toxicity / Wanten, G.J.A. -- Intravenous lipids in preterm infants : impact on laboratory and clinical outcomes and long-term consequences / Vlaardingerbroek, H., Van Goudoever, J.B. -- Intravenous lipid emulsions in term infants : impact on laboratory and clinical outcomes and long-term consequences / Hartman, C., Shamir, R. -- Intestinal failure-associated liver disease and the use of fish oil-based lipid emulsions / Goulet, O.J. -- Intravenous lipids in adult surgical patients / Klek, S., Waitzberg, D.L. -- Intravenous lipids in adult intensive care unit patients / Hecker, M., Mayer, K. -- Intravenous fish oil in adult intensive care unit patients / Heller, A.R. -- Intravenous lipids in home parenteral nutrition / Pironi, L., Agostini, F., Guidetti, M. -- The complexity of prescribing intravenous lipid emulsions / Waitzberg, D.L., Matos de Miranda Torrinhas, R.S. -- Use of intravenous lipids : what do the guidelines say? -- Singer, P., Theilla, M., Cohen, J.
  • 2010
    Betty L. Gahart, Adrienne R. Nazareno.
    Status: Not Checked OutLane Catalog Record
    This edition provides everything you need to administer IV medications quickly, accurately, and safely. ... [Includes] detailed information on 8 IV drugs recently approved by the FDA. --back cover.
  • 2012
    Betty L. Gahart, Adrienne R. Nazareno.
    Status: Not Checked OutLane Catalog Record
  • 2015 Springer
    Albert J. Augustin, editor.
    This book explains how to use intravitreal steroids optimally in the management of patients with intraocular inflammation (uveitis) and macular edema. The rationale for this treatment approach is first explained by examining the pathophysiology of these disease entities, with particular attention to the major role of inflammatory processes. Devices for the delivery of steroids to the eye are discussed, and guidance provided on the role of imaging studies before, during, and after steroid therapy. The value of different steroidal approaches is then considered in detail. Other topics addressed include the use of steroids as a surgical adjunct and within a combination strategy. Uveitis and macular edema are common sight-threatening diseases or complications of diabetes and retinal vein occlusion for which no adequate treatment was available until recently. Both trainees and practitioners will find Intravitreal Steroids to be an invaluable aid in combating these blinding diseases.
  • 2013 Springer
    Bryan R. Cullen, editor.
    The APOBEC3 Family of Retroelement Restriction Factors / Eric W. Refsland, Reuben S. Harris -- Inhibition of Retroviral Replication by Members of the TRIM Protein Family / Adam J. Fletcher, Greg J. Towers -- The Antiviral Activities of Tetherin / Stuart J. D. Neil -- Restriction of Retroviral Infection of Macrophages / Mark Sharkey -- Rapid Adversarial Co-Evolution of Viruses and Cellular Restriction Factors / Welkin E. Johnson -- RNA Interference-Mediated Intrinsic Antiviral Immunity in Plants / György Szittya, József Burgyán -- RNA Interference-Mediated Intrinsic Antiviral Immunity in Invertebrates / Arabinda Nayak, Michel Tassetto, Mark Kunitomi, Raul Andino -- Roles of MicroRNAs in the Life Cycles of Mammalian Viruses / Eva Gottwein -- Interplay Between DNA Tumor Viruses and the Host DNA Damage Response / Karyn McFadden, Micah A. Luftig.
  • 2012
    Ye Emily Wu.
    Nervous system function requires the structural and functional integrity of chemical synapses, the fundamental units of neural communication. Synapse formation requires the packaging of synaptic vesicle (SV) and active zone (AZ) proteins into vesicular cargoes in the cell soma, their long-distance microtubule-dependent transport down the axon and finally, their clustering and assembly into functional complexes at specific sites. The subcellular localization, size, and number of synapses diverse greatly between different types of neurons and are critical determinants of the identity and strength of neural connections. Compared to our knowledge of extrinsic signals and cell-surface molecules that regulate synapse formation and synaptic specificity, less is known about the intrinsic regulatory mechanisms that regulate presynaptic protein transport and assembly to achieve proper spatial distribution of synapses. We have taken advantage of the powerful genetics in Caenorhabditis elegans to investigate this question. Using in vivo time-lapse fluorescence microscopy in a motor neuron DA9 in C. elegans, we show that SV and AZ proteins exhibit extensive co-trafficking and undergo frequent pauses during axonal transport. At the pause sites, the balance between the capture and dissociation of mobile transport packets determines the extent of presynaptic protein clustering. Through forward genetic screens, we identified a molecular regulatory network that controls the capture and dissociation events to dictate the spatial distribution of presynaptic specializations. First, we identified an Arf-like small G protein, ARL-8, that regulates synapse distribution by inhibiting premature clustering of presynaptic cargoes during axonal transport. arl-8 mutants accumulate presynaptic specializations within the proximal axon of several neuronal classes, with a corresponding failure to assemble presynapses distally. Time-lapse imaging analysis revealed that presynaptic cargoes in arl-8 mutants exhibit a decreased tendency to dissociate from immotile clusters and an increased probability of being captured by immotile clusters. We further performed genetic suppressor screens to isolate molecules that functionally interact with arl-8 in presynaptic patterning. We report that loss-of-function mutations in a JKK-1/JNK-1 MAP kinase pathway and several active zone assembly proteins strongly and partially suppress the abnormal distribution of presynaptic proteins in arl-8 mutants. Time-lapse imaging analysis demonstrated that the JNK kinase pathway and active zone assembly molecules inhibit presynaptic protein dissociation. In addition, we found that the kinesin motor UNC-104/KIF1A controls the capture efficiency. Furthermore, UNC-104/KIF1A functions as an effector of ARL-8 by binding specifically to the GTP-bound form of ARL-8. Together, these findings revealed novel intrinsic mechanisms that control the subcellular localization, size, and number of synapses by coordinating axonal transport with presynaptic assembly.
  • 2012 Springer Protocols
    Fulltext v. 2 (v. 896) Springer Protocols
    edited by Vladimir N. Uversky, A. Keith Dunker.
  • 2015 Springer
    Isabella C. Felli, Roberta Pierattelli, editors.
    1. Back to the future: nuclear magnetic resonance and bioinformatics studies on intrinsically disordered proteins -- 2. Structure and dynamics of intrinsically disordered proteins -- 3. NMR methods for the study of intrinsically disordered proteins structure, dynamics, and interactions: general overview and practical guidelines -- 4. Ensemble calculation for intrinsically disordered proteins using NMR parameters -- 5. NMR spectroscopic studies of the conformational ensembles of intrinsically disordered proteins -- 6. Recombinant intrinsically disordered proteins for NMR: tips and tricks -- 7. Biophysical methods to investigate intrinsically disordered proteins: avoiding an "elephant and blind men" situation -- 8. Application of SAXS for the structural characterization of IDPs -- 9. Bioinformatics approaches for predicting disordered protein motifs -- 10. Towards understanding protein disorder in-cell -- 11. The Protein Ensemble Database -- 12. Order and disorder in the replicative complex of paramyxoviruses -- 13. Druggability of intrinsically disordered proteins -- 14. Beta amyloid hallmarks: from intrinsically disordered proteins to Alzheimer's Disease.
    Also available: Print – 2015
  • 2001 HighWire
    Also available: Print – 2001
  • 2006 Springer
    Willard L. Koukkari and Robert B. Sothern.
    The study of biological rhythms -- General features of rhythms : terminology and characteristics -- Physical and biological time -- Photoperiodism -- Biological oscillators and timers : models and mechanisms -- Tidal and lunar rhythms -- Sexuality and reproduction -- Natural resources and agriculture -- Veterinary medicine -- Society -- Clinical medicine -- Autorhythmometry -- Chronobiometry : analyzing for rhythms.
  • Scott M. Lynch.
  • 2007 Springer
    Karl-Rudolf Koch.
  • 2013 ScienceDirect
    edited by Robin Ganellin, Stanley Roberts, Roy Jefferis.
    Chapter 1. Introduction to enzymes, receptors and the action of small molecule drugs -- chapter 2. Protein structure and function -- chapter 3. The small molecule drug discovery process : from target selection to candidate selection -- chapter 4. Protein therapeutics (introduction to biopharmaceuticals) -- chapter 5. Similarities and differences in the discovery and use of biopharmaceuticals and small-molecule chemotherapeutics -- chapter 6. Therapies for type 2 diabetes : modulating the incretin pathway using small molecule peptidase inhibitors or peptide mimetics -- chapter 7. The structure and business of biopharmaceutical companies including the management of risks and resources -- chapter 8. Discovery and development of the anticancer agent gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase -- chapter 9. Targeting HER2 by monoclonal antibodies for cancer therapy -- chapter 10. Recombinant human erythropoietin and its analogues -- chapter 11. Lysosomal storage disorders : current treatments and future directions -- chapter 12. Hormone replacement therapy -- chapter 13. Design of the anti-HIV protease inhibitor darunavir -- chapter 14. The case of anti-TNF agents -- chapter 15. Discovery of the cholesterol absorption inhibitor, ezetimibe.
  • 2013 ScienceDirect
    William Stillwell.
    An Introduction to Biological Membranes: From Bilayers to Rafts covers many aspects of membrane structure/function that bridges membrane biophysics and cell biology. Offering cohesive, foundational information, this publication is valuable for advanced undergraduate students, graduate students and membranologists who seek a broad overview of membrane science. Brings together different facets of membrane research in a universally understandable mannerEmphasis on the historical development of the field. Topics include membrane sugars, membrane models, membrane isolation methods, and membrane transport.
  • pt. 1-2, 2009
    Douglas A. Christensen.
  • 2003 Wiley
    Paras N. Prasad.
    ch. 1. Introduction -- ch. 2. Fundamentals of Light and Matter -- ch. 3. Basics of Biology -- ch. 4. Fundamentals of Light-Matter Interactions -- ch. 5. Principles of Lasers, Current Laser Technology, and Nonlinear -- ch. 6. Photobiology -- ch. 7. Bioimaging: Principles and Techniques -- ch. 8. Bioimaging: Applications -- ch. 9. Biosensors -- ch. 10. Microarray Technology for Genomics and Proteomics -- ch. 11. Flow Cytometry -- ch. 12. Light-Activated Therapy: Photodynamic Therapy -- ch. 13. Tissue Engineering with Light -- ch. 14. Laser Tweezers and Laser Scissors -- ch. 15. Nanotechnology for Biophotonics: Bionanophotonics -- ch. 16. Biomaterials for Photonics.
  • 2007 Springer
    edited by Marcello Barbieri.
  • 2013 Springer
    Andrew M. Luks, Robb W. Glenny, H. Thomas Robertson.
    Cardiopulmonary exercise testing is an important diagnostic test in pulmonary medicine and cardiology. Capable of providing significantly more information about an individual's exercise capacity than standard exercise treadmill or 6-minute walk tests, the test is used for a variety of purposes including evaluating patients with unexplained exercise limitation or dyspnea on exertion, monitoring disease progression or response to treatment, determining fitness to undergo various surgical procedures and monitoring the effects of training in highly fit athletes. Introduction to Cardiopulmonary Exercise Testing is a unique new text that is ideal for trainees. It is presented in a clear, concise and easy-to-follow manner and is capable of being read in a much shorter time than the available texts on this topic. Chapters describe the basic physiologic responses observed during sustained exercise and explain how to perform and interpret these studies. The utility of the resource is further enhanced by several sections of actual patient cases, which provide opportunities to begin developing test interpretation skills. Given the widespread use of cardiopulmonary exercise testing in clinical practice, trainees in pulmonary and critical care medicine, cardiology, sports medicine, exercise physiology, and occasionally internal medicine, will find Introduction to Cardiopulmonary Exercise Testing to be an essential and one of a kind reference.
  • 2007 Springer
    Andrew R. Leach and Valerie J. Gillet.
  • 2012 Cambridge
    edited by S.V. Mahadevan, Gus M. Garmel.
    "The Practitioner's understanding of emergency medicine principles and practice, directly benefiting patient care in a variety of emergency settings An Introduction to Clinical Emergency Medicine, Second Edition is a much-needed resource for individuals practicing this challenging field. This textbook is novel in its approach to emergency medicine topics. It describes in detail the best and most current methods to care for patients in the emergency department, including initial evaluation, generation of differential diagnoses, problem solving, and management of challenging conditions based on presenting symptoms. Unlike other textbooks, in which the diagnosis is known, this textbook approaches clinical problems as clinicians manage patients - without full knowledge of the final diagnosis. It provides an understanding for how to approach patients with undifferentiated conditions, ask the right questions, gather historical data, utilize physical examination skills, and order and interpret appropriate laboratory and radiographic tests. This textbook also provides current management and disposition strategies with controversies presented, including pearls, pitfalls, and myths for topics covered. Chapters are written by nationally- and internationally respected clinicians, educators, and researchers in the field of emergency medicine. Second Edition of An Introduction to Clinical Emergency Medicine offers just the right combination of text, clinical images, and practical information for students, residents, physician assistants, nurse practitioners, and experienced physicians in all medical disciplines"-- Provided by publisher.
    Also available: Print – 2012
  • edited by S.V. Mahadevan, Gus M.Garmel.
    Status: Not Checked OutLane Catalog Record
  • 2003 CRCnetBASE
    Vishwanath M. Sardesai.
    Also available: Print – 2003
  • 2006 Springer
    Bernhard Haubold, Thomas Wiehe.
  • 2007
    Nello Cristianini and Matthew W. Hahn.
    Status: Not Checked OutLane Catalog Record
  • prepared by the Education Committee, Division of Chemical Information, American Chemical Society.
    Instructional materials on how to search Chemical Abstracts online. Includes a guide to effective searching, with annotated search examples.
  • 2008
    Kyriacos A. Athanasiou and Roman M. Natoli.
  • 2012 Springer
    Rob Sullivan.
  • 2014 AccessMedicine
    editor-in-chief, Khaled Elsayes, Sandra Oldham.
    Overview of diagnostic modalities and contrast agents / Navid Zaer, Amini Behrang, and Khaled M. Elsayes -- Introduction to nuclear medicine / David Brandon, Aaron J. Thomas, and Gregory Ravizzini -- Diagnostic neuroradiology / Santosh Shah, Tara Hagopian, Robert Klinglesmith, and Eliana Bonfante -- Cardiothoracic imaging / Nakul Gupta, Sandra A. A. Oldham, and Eduardo J. Matta -- Gastrointestinal imaging / Patrick Marcin, Eduardo Matta, and Khaled M. Elsayes -- Genitourinary system / Usama Salem, Edwardo Matta, Ayda Youssef, and Khaled M. Elsayes -- Musculoskeletal / Behrang Amini and Zeyad Metwalli -- Interentional radiology / Bilal Anwer and Voon P. Liaw -- Pediatric radiology / Megan Speer, Michael Mahlmann, Jennifer Caero, and Ajaykumar Morani -- Introduction to womens imaging / Haitham Elsamaloty, Mohamed Al-Natour, Neda Haswah, Stephanie Holz, and Khaled Elsayes.
  • 2007
    by Susumu Mori.
    Status: Not Checked OutLane Catalog Record
  • 2008 ScienceDirect
    edited by Terence D. Allen.
    Also available: Print – 2008
  • 2012 Wiley
    T.D.H. Bugg.
    Looking at enzymes from an organic chemistry perspective, this updated reference includes information on recent advances in our understanding of enzyme action; topical examples to illustrate key points; two-color figures of the active sites of enzymes discussed in the text to illustrate the interplay between enzyme structure and function; and end-of-chapter problems to allow readers to check their understanding of the material. This concise but comprehensive guide is essential for undergraduate and postgraduate students of organic, bio-organic, and medicinal chemistry, chemical biology, bioche.
  • 2010 Springer
    Jørn Olsen ... [et al.].
    Measures of disease occurrence -- Estimates of associations -- Age standardization -- Causes of diseases -- Descriptive epidemiology in public health -- Descriptive epidemiology in genetic epidemiology -- Descriptive epidemiology in clinical epidemiology -- Design options -- Follow-up studies -- Case-control studies -- The cross-sectional study -- The randomized controlled trial (RCT) -- Analytical epidemiology in public health -- Analytical epidemiology in genetic epidemiology -- Analytical epidemiology in clinical epidemiology -- Confounding and bias -- Confounding -- Information bias -- Selection bias -- Making inference and making decisions -- Sources of error in public health epidemiology -- Sources of error in genetic epidemiology -- Sources of error in clinical epidemiology -- P values -- Calculating confidence intervals -- Erratum to: an introduction to epidemiology for health professionals.
  • 2006
    Ray M. Merrill, Thomas C. Timmreck.
    Status: Not Checked OutLane Catalog Record
  • 2006 NCBI Bookshelf
    editors: Edward B. Bromfield, José E. Cavazos, Joseph I. Sirven.
  • 2012 Cambridge
    edited by Gonzalo Alarcon, Antonio Valentin.
    Preface -- Introduction and basic principles -- Pathology, physiology and neurochemistry of epilepsy -- Clinical neurophysiology -- Semiology and classification; 5. Natural history of epilepsy -- Genetics of epilepsy -- Neuroimaging; 8. Differential diagnosis of epilepsy -- Medical treatment of epilepsy -- Special topics in the diagnosis and treatment of epilepsy -- Neuropsychology -- Surgical treatment of epilepsy -- Psychiatry aspects -- Social aspects -- Epilepsy in the Third World -- Healthcare and economics -- Forensic aspects of epilepsy.
  • 2009 Springer
    Alexander P. Demchenko.
  • 2002 CRCnetBASE
    Rudin Norah, Keith Inman.
    Also available: Print – 2002
  • 2005 ScienceDirect
    Bruce A. Arrigo, Stacey L. Shipley.
  • 2012
    Anthony J.F. Griffiths, Susan R. Wessler, Sean B. Carroll, John Doebley.
    Status: Not Checked OutLane Catalog Record
    1. The Genetics Revolution in the Life Sciences -- pt. I. TRANSMISSION GENETICS -- 2. Single-Gene Inheritance -- 3. Independent Assortment of Genes -- 4. Mapping Eukaryote Chromosomes by Recombination -- 5. The Genetics of Bacteria and Their Viruses -- 6. Gene Interaction -- pt. II. FROM DNA TO PHENOTYPE -- 7. DNA: Structure and Replication -- 8. RNA: Transcription and Processing -- 9. Proteins and Their Synthesis -- 10. Gene Isolation and Manipulation -- 11. Regulation of Gene Expression in Bacteria and Their Viruses -- 12. Regulation of Gene Expression in Eukaryotes -- 13. The Genetic Control of Development -- 14. Genomes and Genomics -- pt. III. MUTATION, VARIATION, AND EVOLUTION -- 15. The Dynamic Genome: Transposable Elements -- 16. Mutation, Repair, and Recombination -- 17. Large-Scale Chromosomal Changes -- 18. Population Genetics -- 19. The Inheritance of Complex Traits -- 20. Evolution of Genes and Traits.
  • 2007 CRCnetBASE
    Aniruddha Datta, Edward R. Dougherty.
    Review of organic chemistry -- Energy considerations in biochemical reactions -- Proteins -- DNA -- Transcription and translation -- Chromosomes and gene regulation -- Genetic variation -- DNA technology -- Cell division -- Cell cycle control, cell death, and cancer -- Expression microarrays -- Classification -- Clustering -- Genetic regulatory networks -- Intervention -- External intervention based on optimal control theory.
  • 2013 Springer
    Manish K. Sethi, William H. Frist, editors.
    Understanding the basics I. The history of health care in the United States pre-1965 / Alexander Ding -- Medicare and its evolution to 2011 / Kevin J. Bozic and Benedict U. Nwachukwu -- Medicaid and the state children's health insurance program / Vasanth Sathiyakumar, Jordan C. Apfeld, and Manish K. Sethi -- Breaking down health care insurance from HMO to PPO and beyond / David Polakoff and Audrey Smolkin -- Understanding quality and cost from a health policy perspective / Jason D. Keune and Bruce Lee Hall -- Understanding the basics II. Prevention and US health care / Heather A. Smith -- The rise of comparative effectiveness research / Michael Hochman and Danny McCormick -- Health information technology : clinical and policy context / Emily R. Maxson and Sachin H. Jain -- Prescription drug and pharmaceutical policy / Phillip A. Choi and Walid F. Gellad -- Health disparities / Neil M. Issar and Manish K. Sethi -- The economics of health care / David A. Rosman and Jordan C. Apfeld -- Understanding systems of health care. The American health-care system : understanding how the pieces come together / Roshan P. Shah and Samir Mehta -- Alternative systems of care and consumer-driven health care / Daniel Guss -- National healthcare systems : a worldview / Benjamin S. Hooe, Perrin T. Considine, and Manish K. Sethi -- Reimbursement : understanding how we pay for health care / Sachin H. Jain and Elaine Besancon -- Understanding the politics in health policy. How health-care policy is made in Washington : understanding the players and the game / Eleby R. Washington IV, Ilisa Halpern Paul, Amy L. Walker, and A. Alex Jahangir -- Government and state agencies : who administrates healthcare on federal and state levels? / Rishin J. Kadakia and Hassan R. Mir -- The 2006 Massachusetts health care reform / Vasanth Sathiyakumar, Jordan C. Apfeld, Cesar S. Molina, Daniel J. Stinner, Andrew Han, and Manish K. Sethi -- The 2010 Patient Protection and Affordable Care Act : what is it and how will it change health care? / Richard Latuska, ALexandra Obremskey, and Manish K. Sethi.
  • 2015 Wiley
    editors, Steven A. Haney and Doug Bowman ; associate editors, Arijit Chakravarty, Anthony Davies, and Caroline Shamu.
    Introduction / Steven Haney -- Fluorescence and cell labeling / Anthony Davies, Steven Haney -- Microscopy fundamentals / Steven Haney, Anthony Davies, Doug Bowman -- Image processing / John Bradley, Doug Bowman, Arijit Chakravarty -- Selecting and setting up a high content imaging platform / Craig Furman, Doug Bowman, Anthony Davies, Caroline Shamu, Steven Haney -- Informatics considerations / Jay Copeland, Caroline Shamu -- Basic high content assay development / Steven Haney, Doug Bowman -- Designing metrics for high content assays / Arijit Chakravarty, Steven Haney, Doug Bowman -- Analyzing well-level data / Steven Haney, Arijit Chakravarty -- Analyzing cell level data / Steven Haney, Lin Guey, Arijit Chakravarty -- Designing robust assays / Arijit Chakrivarty, Doug Bowman, Anthony Davies, Caroline Shamu -- Automation and screening / John Donovan, Arijit Chakravarty, Anthony Davies, Steven Haney, Doug Bowman, John Ringling, Ben Knight -- High content analysis for tissue samples / Kristine Burke, Vaishali Sinde, Alice McDonald, Doug Bowman, Arijit Chakrivarty -- Factoring and clustering high content data / Steven Haney, Arijit Chakravarty -- Supervised machine learning / Jeff Palmer, Arijit Chakravarty.
  • 2014 Springer
    Gregory R. Bowman, Frank Noé, Vijay S. Pande, editors.
    The aim of this book volume is to explain the importance of Markov state models to molecular simulation, how they work, and how they can be applied to a range of problems. The Markov state model (MSM) approach aims to address two key challenges of molecular simulation: 1) How to reach long timescales using short simulations of detailed molecular models 2) How to systematically gain insight from the resulting sea of data MSMs do this by providing a compact representation of the vast conformational space available to biomolecules by decomposing it into states sets of rapidly interconverting conformations and the rates of transitioning between states.This kinetic definition allows one to easily vary the temporal and spatial resolution of an MSM from high-resolution models capable of quantitative agreement with (or prediction of) experiment to low-resolution models that facilitate understanding. Additionally, MSMs facilitate the calculation of quantities that are difficult to obtain from more direct MD analyses, such as the ensemble of transition pathways. This book introduces the mathematical foundations of Markov models, how they can be used to analyze simulations and drive efficient simulations, and some of the insights these models have yielded in a variety of applications of molecular simulation.
    Also available: Print – 2014
  • 2013 CRCnetBASE
    Bernie Rubenzer.
    In the past, for the most part, people who moved into management positions in medical imaging were chosen because they were the best technologists. However, the skill set for technologists and supervisors/managers are vastly different. Even an MBA-educated person may not be ready to take on imaging management. As an example, when buying a very expensive piece of imaging equipment, this person would not necessarily know the right questions to ask, such as: What is my guaranteed uptime? Is technologist training included? Introduction to Medical Imaging Management is a comprehensive reference for.
  • 2010 CRCnetBASE
    Suzanne Bell, Keith Morris.
    Ch. 1. Light and matter -- ch. 2. Fundamentals of light and optics -- ch. 3. Types of microscopes -- ch. 4. Kohler illumination -- ch. 5. Sample preparation, manipulation, and micrometry -- ch. 6. Photomicrography -- ch. 7. Polarized light microscopy -- ch. 8. Basic crystallography -- ch. 9. Chemical microscopy.
  • 2007
    N.J. Dimmock, A.J. Easton, K.N. Leppard.
    Status: Not Checked OutLane Catalog Record
  • 2003 CRCnetBASE
    Jack Tuszynski, Michal Kurzynski.
  • 2012
    Paras N. Prasad.
    Nanomedicine and nanobioengineering fuse nanotechnology with medicine and bioengineering. They are emerging new frontiers, providing challenges for fundamental research and opportunities for revolutionary advances in medical technology. They also provide a global vision to produce breakthrough approaches for meeting our current and future healthcare needs. Introduction to Nanomedicine and Nanobioengineering provides an integrated description of nanomedicine and nanobioengineering for next-generation diagnostics and therapy. It presents a basic introduction to a broad range of topics in an integrated manner, so that individuals in all disciplines in this field. It is intended to serve both as a textbook for education and training, as well as a reference book that aids further advancement in areas integrating nanotechnology with medicine and bioengineering. The book encompasses the fundamentals of nanomaterials design, bioengineering, nanodiagnostics, and nanotherapy. It is intended to benefit investigators adn students from the disciplines of chemistry, physics, and dental school trainees adn practitioners, and scientists from the pharmaceutical and cosmetic industries.
  • 2013 Wiley
    edited by Dario Farina, Winnie Jensen, Metin Akay.
    Neural engineering is a discipline that uses engineering techniques to understand, repair, replace, enhance, or treat diseases of neural systems. Currently, no book other than this one covers this broad range of topics within motor rehabilitation technology. With a focus on cutting edge technology, it describes state-of-the-art methods within this field, from brain-computer interfaces to spinal and cortical plasticity. Touching on electrode design, signal processing, the neurophysiology of movement, robotics, and much more, this innovative volume collects the latest information for a wide ran.
  • Mark H. Holmes.
  • 2015 Springer
    K.J. Hannah ... [and others], editors.
    This book is a primer for nurses on the topic of nursing informatics and presents the fundamental concepts of health information management from a nursing perspective. Nursing informatics has never been more important as contemporary healthcare offers exciting opportunities for the nursing profession to contribute to the design of emerging eHealth models of care and to ensure resources such as electronic health records and mobile technology are pragmatic and fit for purpose. This new edition contains the best available evidence to inspire and support nurses to think critically about both current and future practice. Introduction to Nursing Informatics is designed for use by practicing nurses and students in undergraduate programs of study and includes a number of contributions from leading international experts who have practiced in the field over a number of years. The information is presented and integrated in a purposeful manner to encourage readers to explore the key concepts of nursing practice, information management and its relationship to informatics. Critically, the content is also linked to case-based examples to contextualize the theory presented.
  • 2006 Springer
    edited by Kathryn J. Hannah, Marion J. Ball and Margaret J.A. Edwards.
    Also available: Print – 2006
  • 2012 Wiley
    Steen Hansen, Stig Pedersen-Bjergaard, Knut Rasmussen.
    Introduction to pharmaceutical analysis -- International pharmacopoeias, regulations and guidelines -- Fundamental chemical properties, buffers and pH -- Fundamentals of pharmaceutical analysis -- Titrimetric methods -- Introduction to spectroscopic methods -- UV-spectrophotometry -- IR-spectrophotometry -- Atomic spectrometry -- Fundamentals of chromatography -- Chromatographic separation principles -- Thin-layer chromatography -- High-performance liquid chromatography -- Gas chromatography -- Capillary electrophoresis -- Mass spectrometry -- Miscellaneous chemical techniques -- Sample preparation -- Analytical chemical characteristics of selected drug substances -- Quantification and quality of analytical data -- Chemical analysis of drug substances -- Chemical analysis of final pharmaceutical products -- Bioanalysis.
  • 2003 CRCnetBASE
    Mannfred A. Hollinger.
  • 2006
    [edited by] Michael A. Pagliarulo.
    Status: Not Checked OutLane Catalog Record
  • 2014 Wiley
    Joel S. Owen, Jill Fiedler-Kelly.
    "This useful guide helps pharmaceutical scientists and students learn the requisite information needed to perform mixed effect modeling of pharmacologic data using the NONMEM software package"--Provided by publisher.
  • 2010 Wiley
    Nawin Mishra.
    "Proteomics provides an introductory insight on proteomics, discussing the basic principles of the field, how to apply specific technologies and instrumentation, and example applications in human health and diseases. With helpful study questions, this textbook presents an easy to grasp and solid overview and understanding of the principles, guidelines, and especially the complex instrumentation operations in proteomics for new students and research scientists. Written by a leader in proteomics studies, Proteomics offers an expert perspective on the field and the future of proteomics"--Provided by publisher.
    Also available: Print – v. [52], 2010.
  • 2012 ScienceDirect
    Jorge H. Daruna.
    Historical antecedents -- Immune system basics -- Endocrine-immune modulation -- Neuroimmune modulation -- Stress, contextual change, and disease -- Psychosocial stress: neuroendocrine and immune effects -- Infection, allergy, and psychosocial stress -- Cancer, autoimmunity, and psychosocial stress -- Immune activity and psychopathology -- Immune function enhancement -- Integration and implications.
  • 2006 CRCnetBASE
    Hung T. Nguyen.
  • 2006 CRCnetBASE
    John N.S. Matthews.
  • 2013
    edited by J. Dennis Blessing, J. Glenn Forister.
    Status: Not Checked OutLane Catalog Record
    Introduction -- Essays on research in the health professions -- Ethics in research -- Regulatory protection of human subjects in research -- Funding the research : grants -- The research problem -- Review of the literature -- Methodology -- Clinical investigations -- Survey research -- The clinical review -- Qualitative research -- Community-based participatory research -- Data analysis -- Results -- Discussion -- References -- What to do with what you have -- Writing and publishing in the health professions -- Interpreting the literature.
  • 2008
    Stephen Polgar, Shane A. Thomas.
    Status: Not Checked OutLane Catalog Record
    Methods and health research: discussion, questions, and answers -- Research planning -- Sampling methods and external validity -- Causal research and internal validity: discussion, questions, and answers -- Experimental designs and intervention studies -- Surveys and quasi-experimental designs -- Single case (n=1) designs -- Qualitative research -- Questionnaire design -- Interview techniques and the analysis of interview data -- Observation -- Measurement: discussion, questions, and answers -- Organization and presentation of data -- Measures of central tendency and variability -- Standard scores and normal curve -- Correlation: discussion, questions, and answers -- Probability and sampling distributions -- Hypothesis testing -- Selection and use of statistical tests -- The interpretation of research evidence: Discussion, questions, and answers -- Qualitative data analysis -- Presentation of health science research -- Critical evaluation of published research -- Synthesis of research evidence.
  • 2007
    Ian D. Young.
    Status: Not Checked OutLane Catalog Record
    Genetic counseling and the laws of probability -- Autosomal dominant inheritance -- Autosomal recessive inheritance -- X-linked recessive inheritance -- The use of linked DNA markers -- Germline mosaicism -- Polygenic and multifactorial inheritance -- Cancer genetics -- Balanced chromosome rearrangements -- Other mechanisms of inheritance.
  • 2009 CRCnetBASE
    Owen Jones, Robert Maillardet and Andrew Robinson.
    I. Programming. Setting up -- R as a calculating environment -- Basic programming -- I/O: input and output -- Programming with functions -- Sophisticated data structures -- Better graphics -- Pointers to further programming techniques -- II. Numerical techniques. Numerical accuracy and program efficiency -- Root-finding -- Numerical integration -- Optimisation -- III. Probability and statistics. Probability -- Random variables-- Discrete random variables -- Continuous random variables -- Parameter estimation -- IV. Simulation -- Monte-Carlo integration -- Variance reduction -- Cases studies -- Student projects -- Glossary of R commands -- Programs and functions developed in the text.
  • 2016 Springer
    S. B. Bhattacharyya.
    1. Overview of SNOMED CT -- 2. Need for Clinical Terminology -- 3. SNOMED CT History and IHTSDO -- 4. SNOMED CT Basics -- 5. Extending SNOMED CT -- 6. Enabling SNOMED CT -- 7. SNOMED CT Expressions -- 8. Clinical Analytics with SNOMED CT -- 9. Using SNOMED CT -- 10. SNOMED CT Tips and Tricks -- 11. Overall Assessment. .
  • 2006 Thieme eNeurosurgery
    Sue Corbett [editor] ; foreword by John K. Webb.
    This introductory book presents a comprehensive outline of spine surgery that will provide operating room personnel, spine fellows, spine residents, and other multidisciplinary team members with a firm understanding of the general science concepts, equipment, and key procedures in spinal patient care. Clearly presented figures, illustrations, and photographs illuminate procedural techniques at preoperative, intraoperative, and postoperative stages of treatment.
  • 2014
    Svend Juul, Department of Public Health, Section for Epidemiology, Aarhus University, Aarhus, Denmark, Morten Frydenberg, Department of Public Health, Section for Biostatistics, Aarhus University, Aarhus, Denmark.
    Status: Not Checked OutLane Catalog Record
  • 2013 Cambridge
    Ronald D. Fricker.
    "While the public health philosophy of the 20th Century -- emphasizing prevention -- is ideal for addressing natural disease outbreaks, it is not sufficient to confront 21st Century threats where adversaries may use biological weapons agents as part of a long-term campaign of aggression and terror. Health care providers and public health officers are among our first lines of defense. Therefore, we are building on the progress of the past three years to further improve the preparedness of our public health and medical systems to address current and future BW [biological warfare] threats and to respond with greater speed and flexibility to multiple or repetitive attacks." Homeland Security Presidential Directive 21 Bioterrorism is not a new threat in the 21st century -- thousands of years ago the plague and other contagious diseases were used in warfare -- but today the potential for catastrophic outcomes is greater than it has ever been. To address this threat, the medical and public health communities are putting various measures in place, including systems designed to pro-actively mon- itor populations for possible disease outbreaks"--Provided by publisher.
  • edited by Thomas D. Cook, David L. DeMets.
    Introduction to clinical trials -- Defining the question -- Study design -- Sample size -- Randomization -- Data collection and quality control -- Survival analysis -- Longitudinal data -- Quality of life -- Data monitoring and interim analysis -- Selected issues in the analysis -- Closeout and reporting.
  • 2007
    Kristina M. Ropella.
  • 2003 Wiley
    Paul P. Biemer, Lars E. Lyberg.
    ch. 1. The Evolution of survey process quality -- ch. 2. The Survey process and data quality -- ch. 3. Coverage and nonresponse error -- ch. 4. The Measurement process and its implications for questionnaire design -- ch. 5. Errors due to interviewers and interviewing -- ch. 6. Data collection modes and associated errors -- ch. 7. Data processing: errors and their control -- ch. 8. Overview of survey error evaluation methods -- ch. 9. Sampling error -- ch. 10. Practical survey design for minimizing total survey error.
  • 2007
    Uri Alon.
    Status: Not Checked OutLane Catalog Record
  • 2006
    by George K. York and David A. Steinberg.
  • 2017 AccessSurgery
    edited by Amalia Cochran, Ruth Braga.
    The OR as a study in cultural anthropology / Amalia Cochran -- From start to finish : understanding how we get here / Ruth Braga -- The myth of the kind surgeon / Thomas K. Varghese Jr. -- Who are these people? -- Teamwork and communication in the operating room / Louise Hull and Nick Sevdalis -- The OR and humor / Ruth Braga -- Personalities in the operating room / Ross M. Blagg -- 2015 Grammy awards category : music in the operating room / Marie Crandall -- Welcome to the jungle : the five senses of the operating room / Elizabeth Hanes -- Operating room equipment from A to Z / Diane Tyler and Ruth Braga -- Robot basics-the nurses' perspective / Sebrena Banecker -- My robot experience, or how surgeons learn new techniques / Walter Medlin -- Dancing around the room -- The OR and the surgical field / Karen Porter -- Lines and tubes : what are all of those things sticking out of the patient's body? / Halle Kogan and Thaona D. Garber -- Positioning the patient / Karen Porter -- Patient safety in the OR / Jon Worthen -- Distractions and interruptions in the operating room / Nick Sevdalis and Louise Hull -- Intraoperative photos -- Notes from your attending / Lawrence A. Shirley and Christian Jones -- Tomfoolery, shenanigans, and hazing in surgery / Luke V. Selby -- Privacy -- keep it to yourself! / Ruth Braga -- Keep calm and trust the count / Cynthia Howard.
  • 2015 ebrary, Limited to 1 simultaneous users
    Thomas A. Birkland.
    Introducing the policy process -- Elements of the policy-making system -- The historical and structural contexts of public policy making -- Official actors and their roles in public policy -- Unofficial actors and their roles in public policy -- Agenda setting, power, and interest groups -- Policies and policy types -- Policy design, policy tools, and decisions -- Policy implementation, failure, and learning -- Science and theory in the study of public policy.
  • 2006
    edited by Sidney Bloch.
    Status: Not Checked OutLane Catalog Record
    An historical context / Sidney Bloch and Edwin Harari -- Ethical aspect of psychotherapy practice / Allen R. Dyer and Sidney Bloch -- Research in psychotherapy / Frank Margison and Anthony Bateman -- What is psychotherapy? / Jerome D. Frank -- Individual long-term psychotherapy / Susan Mizen and Jeremy Holmes -- Short-term dynamic psychotherapy / Michael Hobbs -- Cognitive psychotherapy / Nicholas B. Allen -- Behavioural psychotherapy / Lynne M. Drummond and Brett Kennedy -- Crisis intervention / Cynthia Graham and John Bancroft -- Supportive psychotherapy / Sidney Bloch -- Group psychotherapy / Mark Aveline -- Cognitive analytic therapy / Ian B. Kerr and Anthony Ryle -- The conversational model / Russell Meares -- Child and adolescent psychotherapy / Ricky Emanuel -- Psychotherapy with older adults / Jane Garner -- Couple psychotherapy / Michael Crowe -- Sex therapy / John Bancroft -- Family therapy in the adult psychiatric setting / Edwin Harari and Sidney Bloch.
  • 2007
    Steven Jonas, Raymond L. Goldsteen, Karen Goldsteen.
    Status: Not Checked OutLane Catalog Record
    Introduction -- Health care workforce -- Hospitals and other health care institutions -- Primary and ambulatory care -- Government and the health care system -- Financing -- Health care system performance -- From prepaid group medical practice to managed care -- Health care reform.
  • 2014 Wiley
    Ravi Birla, Department of Biomedical Engineering, Cullen College of Engineering, University of Houston, Houston, TX.
    "Covering a progressive medical field, Tissue Engineering describes the innovative process of regenerating human cells to restore or establish normal function in defective organs. As pioneering individuals look ahead to the possibility of generating entire organ systems, students may turn to this textbook for a comprehensive understanding and preparation for the future of regenerative medicine. This book explains chemical stimulations, the bioengineering of specific organs, and treatment plans for chronic diseases, like diabetes. It is a must-read for tissue engineering students and practitioners"--Provided by publisher.
  • 2003 CRCnetBASE
    edited by Michael E. Burczynski.
  • 2014 Springer
    Philip C. Burcham.
    This book provides a readable introduction to modern toxicology with a particular focus on the mechanisms underlying the induction of toxicity by foreign substances. Since bioactivation is central to many toxic syndromes, special interest is devoted to chemicals that undergo conversion to toxic metabolites that induce toxic effects as diverse as cancer, birth defects and organ injury. The molecular consequences accompanying damage to cellular DNA and proteins is explored together with the relevance of toxicological paradigms to human diseases caused by alcohol and tobacco. The discipline of toxicology has developed rapidly since the thalidomide disaster in the 1960?s as scientists worldwide seek to understand the adverse health effects of human medicines, environmental pollutants, consumer chemicals and industrial reagents. An Introduction to Toxicology is intended to supplement the recommended reading list of undergraduate and graduate programs in toxicology and pharmacology as an enjoyable, accessible primer with illustrations that "unpack" the concepts being discussed in the text.
  • 2015 Springer
    Dennis V. Cokkinos, editor.
    Introduction: What Is Translational Research -- Insights into heart development and regeneration -- Basis Of Cell Excitability And Cardiac Conduction System -- The Renin-Angiotensin-Aldosterone System In Cardiovascular Diseases -- Beta adrenergic receptors -- The hypothalamic-pituitary-adrenal axis in human health and disease -- Genetic Polymorphisms -- Genetic Polymorphisms and the Vascular Endothelium -- The role of microRNAs in Cardiovascular Disease -- Pathways To Myocardial Hypertrophy -- The multiple actions of the insulin-like growth factor-I signaling in the myocardium -- Calcium Cycling Circuits in Cardiac Physiology and Pathophysiology -- Inflammation and atherosclerosis -- Stress proteins and the Adaptive Response of the Heart -- The Mechanisms And Modalities Of Cell Death -- Repair of the infarcted myocardium -- Pathways to cardiac remodeling -- A Translational Approach to Probe the Arrhythmic Potential of the Heart: Therapeutic Considerations -- Animal Models Of Cardiovascular Disease -- Experimental in vitro assessment of cardiac function -- In vivo experimental assessment of cardiac function -- Non invasive imaging modalities for Cardiovascular Translational Research- Technical Considerations -- Cardiovascular Applications of Non-Invasive Imaging in Cardiovascular Diseases: from Bench to Bedside -- Molecular Imaging of Inflammation Using Echoardiography: Advances With the Use of Microbubbles -- Clinical Aspects And Genetics Of Cardiomyopathies -- Cardiorenal Syndrome: What Basic Research Can Contribute -- Clinical aspects of Cardiorenal Syndrome: consequences of therapy with the Renin-Angiotensin System Inhibitors -- Pre-, Peri-, and Post-Conditioning the ischemic myocardium: Challenges, Confounders and Expectations -- Gene Therapy for the Heart -- Cell therapy in cardiac diseases -- Moving Towards a Novel Paradigm in Drug Development for Worsening Heart Failure: The T1 Model (Mechanistic Translational Phase).
  • 2007
    Donald A. Barr.
    Status: Not Checked OutLane Catalog Record
    Health, health care, and the market economy -- Health care as a reflection of underlying cultural values and institutions -- The Health professions and the organization of health care -- Health insurance, HMOs, and the managed care revolution -- Medicare -- Medicaid and the State Children's Health Insurance Program -- The Increasing role of for-profit health care -- Pharmaceutical policy and the rising cost of prescription drugs -- Long-term care -- The Uninsured -- Factors other than health insurance that impede access to health care -- Key policy issues for deciding the direction of health care reform -- Where do we go from here? options for health care reform.
  • 2012 ClinicalKey
    [edited by] John S. Pellerito, Joseph F. Polak.
    "Now in its 6th edition, Introduction to Vascular Ultrasonography, by Drs. John Pellerito and Joseph Polak, provides an easily accessible, concise overview of arterial and venous ultrasound. A new co-editor and new contributors have updated this classic with cutting-edge diagnostic procedures as well as new chapters on evaluating organ transplants, screening for vascular disease, correlative imaging, and more. High-quality images, videos, and online access make this an ideal introduction to this complex and rapidly evolving technique."--Publisher's website.
  • 2009
    A.A. Bharath.
  • 2008 Springer
    James A. Marcum.
  • 2002 ebrary
    Peter Dalgaard.
    Also available: Print – 2002
  • Peter Dalgaard.
  • 2006
    Nancy C. Andreasen, Donald W. Black.
    Status: Not Checked OutLane Catalog Record
    Diagnosis and classification -- Interviewing and assessment -- The neurobiology and genetics of mental illness -- Delirium, dementia, and amnestic disorder -- Schizophrenia and other psychotic disorders -- Mood disorders -- Anxiety disorders -- Somatoform, dissociative, and related disorders -- Alcohol and drug-related disorders -- Personality disorders -- Sexual dysfunction, paraphilias, and gender identify disorders -- Eating disorders -- Adjustment disorders -- Impulse-control disorders -- Psychiatric emergencies -- Child psychiatry -- Sleep disorders -- Legal issues -- Psychological treatments -- Psychopharmacology and electroconvulsive therapy.
  • 2011
    Donald W. Black, Nancy C. Andreasen.
    Status: Not Checked OutLane Catalog Record
    Diagnosis and classification -- Interviewing and assessment -- The neurobiology and genetics of mental illness -- Delirium, dementia, and amnestic disorder -- Schizophrenia and other psychotic disorders -- Mood disorders -- Anxiety disorders -- Somatoform, dissociative, and related disorders -- Alcohol- and drug-related disorders -- Personality disorders -- Sexual dysfunction, paraphilias, and gender identity disorders -- Eating disorders -- Adjustment disorders -- Impulse-control disorders -- Psychiatric emergencies -- Child psychiatry -- Sleep disorders -- Legal issues -- Behavioral, cognitive, and psychodynamic treatments -- Psychopharmacology and electroconvulsive therapy.
  • 2010 Springer
    Adriano Tagliabracci ; [with contributions by] F. Alessandrini ; presentazione a cura di Angelo Fiori.
  • 2005 CRCnetBASE
    Marcel Roberfroid.
  • 2011 Springer
    Mario Negrello.
    pt. 1. Invariants of behavior -- pt. 2. Neurodynamics of embodied behavior.
  • 2007 Springer
    PierFrancesco Bassi, Francesco Pagano, editors.
  • 2014 Springer
    Ricardo H. Bardales, editor.
    Chapter 1. Ultrasound, general considerations -- Chapter 2. The interventional cytopathologist -- Chapter 3. The thyroid gland -- Chapter 4. The parathyroid gland -- Chapter 5. The salivary glands -- Chapter 6. The head and neck, miscellaneous lesions -- Chapter 7. The lymph nodes -- Chapter 8. The breast -- Index.
  • 2014 Springer
    Gauri Mankekar, editor.
    Incidence of invasive fungal sinusitis has been increasing over the years. The understanding of its pathophysiology has improved with newer serological tests and diagnostic methods helping in earlier diagnosis and reducing patient morbidity. It was believed earlier that invasive fungal sinusitis is seen only in immune compromised patients but clinical reports suggest otherwise. More anti-fungal drugs are being added to improve incidence of patient survival. This book aims to compile all practical information about invasive fungal sinusitis into a single volume. Therefore, busy clinicians would not have to perform exhaustive literature studies to diagnose invasive fungal sinusitis. The book aims to provide an overview of diseases which could be mistaken for invasive fungal sinusitis and discuss how the management is different. Book sections consist of clinical, microbiological, serological, pathological, radiological and pharmacological features of the disease and its management. Each section is important in today's context as it dynamically alters the management of the patient. Early clinical suspicion and rapid microbiological, pathological and radiological diagnosis with aggressive treatment with surgical debridement and medical therapy leads to favorable outcomes.
  • v. 4, 1949.
    Status: Not Checked OutLane Catalog Record
    1. Sciences générales de l'homme -- 2. Sciences juridiques, politiques et économiques -- 3. Sciences pures et appliquées -- 4. Sciences médicales, biomédicales, pharmaceutiques et vetinaires.
  • 2011
    Rodrigo Alvarez-Icaza Rivera.
    In this dissertation, I revisit Kawato's proposal, that the cerebellum predictively modulates descending motor commands, to achieve smooth and coordinated motion, by acquiring an inverse model of the biomechanical plant, and extend it by describing a novel and precise mapping between a cerebellar multizonal microcomplex and a joint's inverse model. This mapping renders two novel predictions: First, inferior olive's oscillations mirror the biomechanical joint's oscillations. Second, deep cerebellar neurons implement a gain factor, set by Purkinje cell inhibition, on inferior olive's signals to mirror the spinal cord's gain. I use biophysical modeling to show that oscillations within the inferior olive match the range of natural frequencies and damping ratios of biophysical joints, and that deep cerebellar neurons enable a multiplicative interaction between the Purkinje and the olivary pathways. Furthermore, I determine the effects of current injection into the inferior olive and the deep cerebellar nuclei and use these results within a control theory model to predict that experimentally disturbing the inferior olive will introduce motor output ringing, while disturbing the deep nuclei will also scale motor output. In both cases, manipulating the inverse model implemented by microzonal microcomplex will unmask the joint's natural dynamics as observed by motor ringing at the joint's natural frequency.
  • 2013 ScienceDirect
    edited by Randolf Menzel, Paul R. Benjamin.
    Beyond the cellular alphabet of learning and memory in invertebrates / Randolf Menzel and Paul R. Benjamin -- Action selection / M. Heisenberg -- Cognitive components of insect behavior / Martin Giurfa and Randolf Menzel --Exploring brain connectivity in insect model systems of learning and memory / Jürgen Rybak -- 'Decision making' in larval Drosophila / Michael Schleyer, Sören Diegelmann, Birgit Michels, Timo Saumweber and Bertram Gerber -- Optophysiological approaches to learning and memory in Drosphila melanogaster / Thomas Riemensperger and André Fiala -- Computational analyses of learning networks / Douglas A. Baxter, Enrico Cataldo and John H. Byrne -- Issues in invertebrate learning raised by robot models / Barbara Webb -- Mechanosensory learning and memory in Caenorhabditis elegans / Andrea H. McEwan and Catharine H. Rankin -- Molecular and cellular circuits underlying Caenorhabditis elegans olfactory plasticity / Joy Alcedo and Yun Zhang -- Thermosensory learning in Caenorhabditis elegans / Hirouyuki Sasakura and Ikue Mori -- Age-dependent modulation of learning and memory in Caenorhabditis elegans / Shin Murakami -- Salt chemotaxis learning in Caenorhabditis elegans / Yuichi Iino -- A systems analysis of neural networks underlying gastropod learning and memory / Paul R. Benjamin -- Comparison of operant and classical conditioning of feeding behavior in Aplysia / Riccardo Mozzachiodi, Douglas A. Baxter and John H. Byrne -- Mechanisms of short-term and intermediate-term memory in Aplysia / Robert D. Hawkins, Igor Antonov and Iksung Jin -- Synaptic mechanisms of induction and maintenance of long-term sensitization memory in Aplysia / David L. Glanzman -- Roles of protein kinase C and protein kinase M in Aplysia learning / Margaret Hastings, Carole A. Farah adn Wayne S. Sossin -- Multisite cellular and synaptic mechanisms in Hermissenda Pavlovian conditioning / Terry Crow and Nan Ge Jin -- Molecular and cellular mechanisms of classical conditioning in the feeding system of Lymnaea / Gyorgy Kemenes -- Operant conditioning of respiration in Lymnaea / Ken Lukowiak and Sarah Dalesman -- Associative memory mechanisms in terrestrial slugs and snails / Alan Gelperin -- Observational and other types of learning in Octopus / Piero Amodio and Graziano Fiorito -- The neurophysiological basis of learning and memory in advanced vertebrates / Binyamin Hochner and Tal Shomrat -- Learning, memory, and brain plasticity in cuttlefish (Sepia officinalis) / Ludovic Dickel, Anne-Sophie Darmaillacq, Christelle Joset-Alves and Cécile Bellanger -- A multidisciplinary approach to learning and memory in the crab Neohelice (Chasmagnathus) granulata / Daniel Tomsic and Arturo Romano -- Drosphila memory research through four eras / Seth M. Tomchik and Ronald L. Davis -- Visual learning and decision making in Drosphila melanogaster / Aike Guo, Huimin Lu, Ke Zhang, Qingzhong Rena nd Yah-num Chiang Wong -- In search of the engram in the honeybee brain / Randolf Menzel -- Neural correlates of olfactory learning in the primary olfactory center of teh honeybee brain / Jean-Christophe Sanidoz -- Mermory phases and signaling cascades in honeybees / Uli Muller -- Pheremones acting as social signals modulate learning in honeybees / Elodie Urlacher, Jean-Marc Devaud and Alison R. Mercer -- Extinction learning and memory formation in the honeybee / Dorothea Eisenhardt -- Glutamate neurotransmission and appetitive olfactory conditioning in the honeybee / Gérard Leboulle -- Cellular mechanisms of neuronal plasticity in the honeybee brain / Bernd Grünlatt -- Behavioral and neural analyses of punishment learning in honeybees / Stevanus Rio Tedjakumala and Martin Giurfa -- Breain aging and performance plasticity in honeybees / Daniel Munch and Gro V. Amdam -- Learning and recognitionof identity in ants / Patrizia D'ettorre -- Bounded plasticity in the desert ant's navigational tool kit / Rüdiger Wehner and Wolfgagn Rössler -- Learning and decision making in a social context / Nigel R. Franks and Ana B. Sendova-Franks -- Olfactory and visual learning in cockroaches and crickets / Makoto Mitzunami, Yukihisa Matsumoto, Hidehiro Watanabe and Hiroshi Nishino -- Individual recognition and the evolution of learning and memory in Polistes paper wasps / Elizabeth A. Tibbetts and Michael J. Sheehan.
  • 2015 Springer
    Juan Carlos Kaski, Michael Papadakis, Hariharan Raju, editors
    Angina -- Heart Failure -- Atrial Fibrillation -- Syncope and sudden death -- Systemic Hypertension -- Pulmonary Hypertension.
  • 2007 CRCnetBASE
    Bobbi Jo O'Neal.
  • 2009
    Meng How Tan.
    Status: Not Checked OutLane Catalog Record
  • 2003 CRCnetBASE
    by Dawn Perlmutter.
    1. Contemporary religious violence -- 2. Millennial religions and terrorism -- 3. Domestic terrorist religions -- 4. International terrorist religions -- 5. Satanism -- 6. Vampirism -- 7. Syncretic religions -- 8. Ritualistic crime scenes -- 9. Intelligence strategies -- 10. Symbolic analysis : ritual homicide typology -- Glossary -- Index.
  • 2013
    Mridu Kapur.
    The intracellular trafficking of vesicles and organelles is essential for all cells. Neurons are especially reliant on cargo transport as a consequence of their extremely polarized morphology. Highlighting this point, disruption of axonal transport has been attributed to many neurodegenerative diseases. In recent years, tremendous progress has been made towards a better understanding of the fundamental elements of axonal transport. However, the regulatory mechanisms that control its dynamics remain largely unknown. One striking feature of the axonal transport system is that the retrograde transport of endosomes within axons proceeds with remarkable speed and uniformity, despite having to navigate a complex and crowded environment. In this dissertation, I propose a role for BPAG1n4, a massive 600kDa protein, in the regulation of the processivity of axonal transport. BPAG1n4 has previously been shown to play an essential role in retrograde axonal transport by virtue of its interactions with the dynactin subunit p150Glued, and with endosomes via retrolinkin. Its ability to interact with the main components of the transport system make it ideally placed to coordinate retrograde transport. Here, I show that BPAG1n4 interacts with EB1 family proteins at the microtubule plus end. Using single molecule labeling coupled with live imaging, I found that expression of the isolated plus end binding domain results in a substantial impairment in the processivity of retrograde axonal transport in dorsal root ganglion (DRG) neurons. This suggests that the accessibility of the microtubule plus end to proteins such as BPAG1n4 is essential for maintaining the processive motility of endosomes along the axon. Interestingly, I have discovered an extremely rapid, calcium regulated switch between microtubule plus end interaction and lattice binding in the carboxyl terminus of BPAG1n4. This novel, calcium dependent regulatory mechanism is EF-hand dependent, and mutations of the EF-hands abolish this dynamic behavior. This study represents the first evidence of calcium signaling directly modulating the dynamic interaction of a protein with microtubules. Strikingly, I observed that disruption of the calcium responsiveness of BPAG1n4's association with the plus end severely impaired processive endosomal transport, suggesting the exciting possibility that calcium may play a role in regulating the traffic of endosomes along axons. This study thus provides exciting new insight into the molecular mechanisms that regulate the complex system of axonal transport. This domain of BPAG1n4 is conserved in other members of the spectraplakin family, suggesting that calcium regulation of microtubule plus end interaction may play a vital role in their functional activities as well. Addressing the potential role of this calcium switch may be crucial to fully understanding the diverse functional activities of spectraplakins in microtubule based cellular processes.
  • 2009
    Sara Temiyasathit.
    Status: Not Checked OutLane Catalog Record
  • 2012
    Angela N. Bowman.
    In order for a tissue to be properly sized and patterned, enormous care must be taken to ensure that cell proliferation and differentiation are tightly regulated. The embryonic brain must execute a temporally and spatially defined developmental scheme, resulting in the production of millions of cells of multiple lineages. These cells and their resultant functional architecture must be maintained in the homeostatic adult mouse brain. These processes are in part controlled by external signaling factors, which include Wnts, and their transcriptional programs. However, the degree to which and exact mechanisms by which cell fate choices--including self-renewal, proliferation, and differentiation--are controlled by Wnt/ss-catenin signaling are unknown. Here, I describe studies to investigate these questions. First, I show the identification of a novel target of Wnt/sscatenin signaling, Pou6f1, which mediates neural differentiation and proliferation in embryonic neural progenitor cells. Next, I illustrate the use of a lineage tracing approach using a Wnt/ss-catenin target gene, Axin2, to identify and trace sites of Wnt/ss-catenin responsiveness in the developing and adult mouse brain and central nervous system. Using this same Axin2CreERT2 mouse, I describe the functional consequences of loss of sscatenin from Axin2-expressing cells. Axin2CreERT2 labels numerous radial glial cell populations throughout the central nervous system, three of which serve as functional stem/progenitor populations. Loss of ss-catenin from adult Axin2+ populations results in tissue architecture defects and increased proliferation, presumably because Wnt serves as a self-renewal signal. These studies demonstrate the importance of Wnt/ss-catenin signaling for mediating multiple cell fate choices during the development and homeostasis of the mouse central nervous system, and suggest mechanisms by which neural stem/progenitor populations could be manipulated for therapeutic outcomes.
  • 2007
    Kirstin Suzanne Knox.
    Status: Not Checked OutLane Catalog Record
  • 2009/2010
    Mindy Claire DeRouen.
    Status: Not Checked OutLane Catalog Record
  • 2016 Springer
    Lulu Zhang, Meina Li, Feng Ye, Tao Ding, Peng Kang.
    Part I Pandect -- Background -- Chinese Public Hospital Reform Investigation -- Basic Information of the Survey of Large Public Hospital Reform -- Part II Series Survey Reports of Large Public Hospital Reform -- Investigation on Public Welfare of Public Hospital -- Satisfaction Survey of Outpatients in Large Public Hospital -- Investigation of Health Seeking in Large Public Hospital Patients -- Research on Welfare of Doctors in Large Public Hospitals -- Study of Two-way referral of large public hospital -- The Survey of Multi-sited License in Major Public Hospitals -- Part III Comparative Analysis of Basic Situation of Large Public Hospital Reform -- Comparative Analysis of Basic Situation of Large Public Hospital between Beijing and Shanghai -- Comparative Analysis of Personnel Situation of Large Public Hospital between Beijing and Shanghai -- Comparative Analysis of Medical Business Volume of Large Public Hospital between Beijing and Shanghai -- Comparative Analysis of Service Efficiency of Large Public Hospital between Beijing and Shanghai -- Comparative Analysis of Medical Quality of Large Public Hospital between Beijing and Shanghai -- Comparative Analysis of Talents of Large Public Hospital between Beijing and Shanghai -- Comparative Analysis of Research Situation of Large Public Hospital between Beijing and Shanghai -- Comparative Analysis of Research Situation of Large Public Hospital between Beijing and Shanghai -- Comparative< Analysis of Research Result with "the Fourth National Health Service Survey Report" -- Part IV Conclusions -- Overall Assessment and Policy Recommendations.
  • 2014 CRCnetBASE
    edited by Matthew Eckwahl, MPhil.
    Part 1. Cell polarity, growth, and cell cycle -- part 2. Yeast regulatory circuits -- part 3. Gene expression and trait locus analysis -- part 4. Comparative genomics.
  • 2007 Springer
    Pentti Rautaharju and Farida Rautaharju.
  • 2005 CRCnetBASE
    edited by Helen Tryphonas, Michel Fournier, Barry R. Blakley ... [et al.].
    Also available: Print – 2005
  • 2013
    Jeffrey Levi [and others].
    Examines federal and state public health funding for preventive care and state variations in disease rates, healthcare access, and other data. Calls for adequate levels of investment on a sustained basis and cites examples of prevention efforts.
  • 2007 Springer
    David H. Gustafson, Patricia Flatley Brennan, and Robert P. Hawkins, editors ; foreword by Stephen M. Shortell.
    Patient-focused technology and the health care delivery system / Patricia Flatley Brennan -- CHESS : translating research into practice / Robert P. Hawkins and Susan Dinauer -- Theory and literature review / Robert P. Hawkins and John Fellows -- Considerations for successful implementation of newly adopted technologies / David H. Gustafson and John Fellows -- Implementation model development and testing / David H. Gustafson, Kuang-Yi Wen, and John Fellows -- Introduction to case studies / David H. Gustafson -- Associated Practice, 1992-1997 / Susan Dinauer, Pauley R. Johnson, Tracy Siegler, Gail Casper, and John Fellows -- Union Hospital, 1993-2001 / Susan Dinauer, Betta Owens, Tracy Siegler, Gail Casper, and John Fellows -- Strand Hardin Health Care, 1995-2002 / Tracy Siegler, Betta Owens, Gail Casper, and John Fellows -- Grace Hospital, 1996-2000 / Pauley R. Johnson, Robert P. Hawkins, Joanna Bates, Gail Casper, and John Fellows -- Simpson Hospital, 1997-2000 / Pauley R. Johnson, Susan Dinauer, Gail Casper, and John Fellows -- Caregiver Resource Center Network, 1999-2002 / Leah Eskenazi, Pauley R. Johnson, Tracy Siegler, Gail Casper, and John Fellows -- Key learning and advice for implementers / David H. Gustafson and Patricia Flatley Brennan.
  • 2015 WHO
    Also available: Print – 2015
  • Fleuriet, Michel.
    Status: Not Checked OutLane Catalog Record
  • 2010
    Ethan Oblivion Kung.
    Biomechanical forces such as hemodynamic parameters and stress and strain in blood vessel walls have significant effects on the initiation and development of cardiovascular diseases, as well as on the operations of implantable medical devices. Computational fluid dynamics is an emerging powerful numerical tool capable of providing fine temporal and spatial resolutions in the quantifications of these cardiovascular biomechanical forces. The overall goal of this research is to develop tools and methods for conducting in-vitro experiments, and to acquire experimental data for the validation of the computational methods. We first developed a physical Windkessel module which can provide realistic vascular impedances at the outlets of flow phantoms in order to enable in-vitro experiments that mimic in-vivo conditions. We also defined a corresponding analytical model of the Windkessel module, and showed that upon proper characterization, the analytical model can accurately predict the pressure and flow relationships produced by the physical Windkessel module. The precise analytical model can then be prescribed as a boundary condition for the finite element domain, resulting in a direct parallel between the computational description of the physical model and the physical reality. We then performed validation of the numerical method using the Windkessel module, and a rigid, two outlet, patient-derived abdominal aortic aneurysm phantom under resting and light exercise flow and pressure conditions. Physiological pressures within the phantom, and flow waveforms through the two phantom outlets were achieved. Finally, we performed validation of the numerical method incorporating deformable vessel walls, using two compliant flow phantoms under physiological flow, pressure, and deformation conditions. The compliant phantoms mimicked a patent thoracic aorta, and one with an 84% coarctation (by area). The computational predictions of pressure, flow, and velocity patterns compared favorably with experimental measurements in both of the validation studies. The accurate prediction of wave propagation behaviors in the deformable phantom study indicated a faithful prediction of the vessel wall motion. In addition to numerical methods validation, the experimental techniques we have developed can also be used in direct in-vitro evaluations of medical devices.
  • 2009
    Harry L. Ioachim, L. Jeffrey Medeiros.
    Status: Not Checked OutLane Catalog Record
  • 2009
    first draft prepared by John F. Risher and L. Samuel Keith.
  • 1996 ScienceDirect
    Edward C. Conley ; with contributions from William J. Brammar.
    1. Extracellular ligand-gated channels -- 2. Intracellular ligand-gated channels -- 3. Inward rectifier and intercellular channels -- 4. Voltage-gated channels.
  • 2013 Springer Protocols
    edited by Nikita Gamper.
    1. Approaches to cloning of pain-related ion channel genes / Armen N. Akopian -- 2. Mammalian expression systems and transfection techniques / Daunia Laurenti and Lezanne Ooi -- 3. Use of Escherichia coli for the production and purification of membrane proteins / Vincent G.L. Postis, Andrea E. Rawlings, Amelia Lesiuk, and Stephen A. Baldwin -- 4. Transient overexpression of genes in neurons using nucleofection / Hannah M. Kirton, Louisa Pettinger, and Nikita Gamper -- 5. Viral gene delivery : optimized protocol for production of high titer lentiviral vectors / James Hewinson, Julian F.R. Paton, and Sergey Kasparov -- 6. Two-electrode voltage clamp / Bingcai Guan, Xingjuan Chen and Hailin Zhang -- 7. Conventional micropipette-based patch clamp techniques /Jonathan D. Lippiat and David C. Wrighton -- 8. Recording of ion channel activity in planar lipid bilayer experiments / Eleonora Zakharian -- 9. Recording macroscopic currents in large patches from Xenopus oocytes / Tibor Rohacs -- 10. Combined single-channel and macroscopic recording techniques to analyze gating mechanisms of the large conductance Ca²⁺ and voltage activated (BK) potassium channel / Nguyen V. Nguyen, Aleksandra Gruslova, Wojciech A. Kosiba and Bing Wang -- 11. Perforated whole-cell patch-clamp recording / John E. Linley -- 12. Piezo-electrically driven mechanical stimulation of sensory neurons / Jizhe Hao, Jérôme Ruel, Bertrand Coste, Yann Roudaut, Marcel Crest and Patrick Dlemas -- 13. Automated planar patch-clamp / Carol J. Milligan and Clemens Möller -- 14. Recording single-channel currents using "smart patch-clamp" technique / Anamika Bhargava and Julia Gorelik -- 15. Using total internal reflection fluorescence microscopy to observe ion channel trafficking and assembly / Sarah Schwarzer, Gregory I. Mashanov, Justin E. Molloy, and Andrew Tinker -- 16. Förster resonance energy transfer-based imaging at the cell surface of live cells / Sonya M. Bierbower and Mark S. Shapiro -- 17. Use of dansyl-calmodulin to study interactions with channels and other proteins / Alessandro Alaimo, Covadonga Malo, Pilar Areso, Kerman Aloria, Oscar MIllet and Alvaro Villarroel -- 18. Imaging and quantification of recycled K[subscript ATP] channels / Christopher J. Cockcroft -- 19. Generation of antibodies that are externally acting isoform-specific inhibitors of ion channels / Jacqueline Naylor and David J. Beech -- 20. Site-directed mutagenesis to study the structure-function relationships of ion channels / Wei Yang and Lin-Hua Jiang -- 21. Cysteine-based cross-linking approach to study inter-domain interactions in ion channels / Lin-Hua Jiang -- 22. Analysis of Ca²⁺⁻ binding sites in the MthK RCK domain by x-ray crystallography / Frank J. Smith and Brad S. Rothberg -- 23. Isotope labeling strategies for analysis of an ion channel cytoplasmic domain by NMR spectroscopy / Karin Abarca-Heidemann, Elke Duchardt-Ferner, Jens Woehnert and Brad S. Rothberg -- 24. Recording dendritic ion channel properties and function from cortical neurons / Mala M. Shah -- 25. M-current recording from acute DRG slices / Kirstin E. Rose, Sylvain Gigout, and Nikita Gamper -- 26. Studying ion channels in human erythrocytes by direct and indirect means / Stephan M. Huber -- 27. Recording ion channels in isolated, split-opened tubules / Elena Mironova, Vladislav Bugay, Oleh Pochynyuk, Alexander Staruschenko and James D. Stockand -- 28. Single-channel analysis of TRPC channels in the podocytes of freshly isolated glomeruli / Daria V. Ilatovskaya and Alexander Staruschenko -- 29. Ca²+ imaging as a tool to assess TRP channel function in murine distal nephrons / Mykola Mamenko, Oleg Zaika, Roger G. O'Neil and Oleh Pochynyuk -- 30. Patch-clamping Drosophila sensory neurons / Volodymyr Kucher, Benjamin A. Eaton, James D. Stockand and Nina Boiko -- 31. Production and validation of recombinant adeno-associated virus for channelrhodopsin expression in neurons / John Y. Lin -- 32. Optical control of ligand-gated ion channels / Stephanie Szobota, Catherine McKenzie, and Harald Janovjak.
  • 2006 Springer Protocols
    edited by James D. Stockand, Mark S. Shapiro.
    A simple in-vivo method for assessing changes of membrane bound ion channel density in xenopus oocytes / Mouhamed S. Awayda ... [et al.] -- Preparation of cortical brain slices for electrophysiological recording / Costa M. Colbert -- Juxtacellular labeling and chemical phenotyping of extracellulary recorded neurons in vivo / Glenn M. Toney and Lynette C. Daws -- Carbon fiber amperometry in the study of ion channels and secretion / Duk-Su Koh -- Genetic screening for functionality of bacterial potassium channel mutants using K+ update-deficient escherichia coli / Lyubov V. Parfenova and Brad S. Rothberg -- KCNQ1 K channel-mediated cardiac channelopathies / Gildas Loussouarn, Isabelle Baro, and Denis Escade -- Tissue-specific transgenic and knockout mice / Andrée Porret ... [et al.]. Functional reconstitution of the human epithelial Na+ channel in a mammalian expression system / Alexander Staruschenko ... [et al.] -- Overexpression of proteins in neurons using replication-deficient virus / Richard M. Ahlquist and Jane M. Sullivan -- Exogenous expression of proteins in neurons using the biolistic particle delivery system / Nikita Gamper and Mark S. Shapiro -- Tertiary and quaternary structure formation of voltage-gated potassium channels / John M. Robinson, Andrey Kosolapov, and Carol Deutsch -- Biophysical approach to determine the subunit stoichiometry of the epithelial sodium channel using the xenopus laevis oocyte expression system / Farhad Kosari, Shaou Sheng, and Thomas R. Kleyman -- Spectroscopy-based quantitative fluorescence resonance energy transfer analysis / Jie Zheng -- Probing the effects of phosphoinositides on ion channels / Chou-Long Huang -- Epithelial sodium channel in planar lipid bilayers / Bakhrom K. Berdiev and Dale J. Benos --
  • ScienceDirect
    edited by Bernardo Rudy, Linda E. Iverson.
    Also available: Print – 1992
  • ScienceDirect
    edited by P. Michael Conn.
    Also available: Print – 1998
  • ScienceDirect
    edited by P. Michael Conn.
    Also available: Print – 1999
  • v. 1-2, 1972.
    Status: Not Checked OutLane Catalog Record
    v. 1. Levels -- v. 2. Effects.
  • 2015 Springer Protocols
    edited by Gabriela K. Popescu.
    1. Assaying AMPA Receptor Oligomerization / Catherine L. Salussolia, Quan Gan, Lonnie P. Wollmuth -- 2. A Step-by-Step Guide to Single-Subunit Counting of Membrane-Bound Proteins in Mammalian Cells / Mark R. Aurousseau, Hugo McGuire, Rikard Blunck, Derek Bowie -- 3. Counting NMDA Receptors at the Cell Surface / Martin Horak, Young Ho Suh -- 4. Electrophysiological Tagging of Ionotropic Glutamate Receptors / Andres Barria -- 5. Electron Microscopy Analysis of AMPA Receptors in Dendritic Spines / Audra A. Kramer, Amber N. Petersen, Nashaat Z. Gerges -- 6. Functional Detection of Novel Triheteromeric NMDA Receptors / Sanjay S. Kumar -- 7. Expression, Purification, and Crystallization of Full Length Ionotropic Glutamate Receptors / Maria V. Yelshanskaya, Kei Saotome, Minfen Li, Alexander I. Sobolevsky -- 8. NMR Approaches to Functional Dynamics of Genetically Separated iGluR Domains / Christopher P. Ptak, Ahmed H. Ahmed, Robert E. Oswald -- 9. Computing Conformational Free Energies of iGluR Ligand-Binding Domains / Alvin Yu, Tyler Wied, John Belcher, Albert Y. Lau -- 10. LRET Methods for Investigating Conformational Changes in Functional Ionotropic Glutamate Receptors / Rita E. Sirrieh, Vasanthi Jayaraman -- 11. Assaying the Energetics of NMDA Receptor Pore Opening / Rashek Kazi, Melissa Daniel, Lonnie P. Wollmuth -- 12. Constructing a Rapid Solution Exchange System / David M. MacLean -- 13. Assessing The Effects of Ligand-Binding Mutations to AMPA and Kainate Receptor Kinetics / Mark W. Fleck -- 14. Analysis of Whole-Cell NMDA Receptor Currents / Vojtech Vyklicky, Miloslav Korinek, Ales Balik, Tereza Smejkalova, Barbora Krausova, Ladislav Vyklicky -- 15. Calcium Imaging to Study NMDA Receptor-mediated Cellular Responses / Kelly A. Krogh, Stanley A. Thayer -- 16. Timing AMPA Receptor Activation with Laser-Pulse Photolysis / Li Niu -- 17. Current Recording and Kinetic Analyses for Single AMPA Receptors / Kinning Poon, Robert E. Oswald, Linda M. Nowak -- 18. Extracting Rate Constants for NMDA Receptor Gating from One-Channel Current Recordings / Kirstie A. Cummings, Gary J. Iacobucci, Gabriela K. Popescu.
  • 2011 ProQuest Safari
    J.D. Biersdorfer.
    Looks at the features and functions of the iPad2, covering such topics as accessing the Internet, setting up an email account, using built-in apps, playing games, using iTunes, watching videos, and syncing with MobileMe.
  • 2010 ProQuest Safari
    by Edward C. Baig and Bob LeVitus.
    "Part iPod touch, part MacBook, part eReader, and all amazing, the iPad combines the best of your favorite gadgets into one ultraportable touch device. This handy guide helps you make the most of your iPad. From sending e-mail and surfing the Web to playing games, watching videos, downloading cool apps and more, the fun begins right here"--P. [4] of cover.
  • 2010 ProQuest Safari
    Martin Trautschold and Gary Mazo.
    Pt. I. Quick start guide -- pt. II. Introduction -- pt. 3. You and your iPad. Getting started -- Typing tips, copy/paste & search -- Sync your iPad with iTunes -- WiFi and 3G connections -- Moving, docking, and deletingicons -- Personalize and secure your iPad -- Playing music -- iBooks and E-books -- Viewing videos, tv shows, & more -- Bluetooth on the iPad -- Surf the web with Safari -- E-mail -- Working with contacts -- Your calendar -- Working with photos -- Maps -- Eliminate your paper notes -- iWork : productivity on your iPad -- iTunes on your iPad -- Amazing App Store -- Games and fun -- Social networking -- New media : reading newspapers, magazines, and more -- Other sync methods -- Troubleshooting -- pt. IV. iPad's soulmate : iTunes. Your iTunes user guide.
  • 2010 ProQuest Safari
    J.D. Biersdorfer.
    Looks at the features and functions of the iPad, covering such topics as using Safari, setting up an email account, using built-in apps, playing games, using iTunes, watching videos, syncing with MobileMe.
  • 2007 WHO
    IPCS.
    The use of structured frameworks in chemical risk assessment promotes transparent, harmonized approaches. This publication presents two IPCS frameworks originally published in Critical Reviews in Toxicology. Part 1 contains the IPCS Framework for Analyzing the Relevance of a Cancer Mode of Action for Humans, along with three case studies illustrating its application. Part 2 contains the IPCS Framework for Analyzing the Relevance of a Non-Cancer Mode of Action for Humans. The frameworks provide a means of ensuring a transparent evaluation of the data, identification of key data gaps and of information that would be of value in the further risk assessment of the chemical in question.--Publisher's description.
    Also available: Print – 2007
  • 2012
    Laura Kelly.
    "This book is the first comprehensive history of Irish women in medicine in the late nineteenth and early twentieth centuries. It focuses on the debates surrounding women's admission to Irish medical schools, the geographical and social backgrounds of early women medical students, their educational experiences and subsequent careers. It is the first collective biography of the 760 women who studied medicine at Irish institutions in the period and, in contrast to previous histories, puts forward the idea that women medical students and doctors were treated fairly and often favourably by the Irish medical hierarchy. It highlights the distinctiveness of Irish medical education in contrast with that in Britain and is also unique in terms of the combination of rich sources it draws upon, such as official university records from Irish universities, medical journals, Irish newspapers, Irish student magazines, the memoirs of Irish women doctors, and oral history accounts." -- [Publisher-supplied data]
  • 2013 Springer
    B. Rowe Byers, editor.
    Iron Acquisition by the Genus Mycobacterium summarizes the early evidence for the necessity of iron in mycobacteria and the discovery of the mycobacterial siderophores mycobactin, carboxymycobactin, and exochelin. The structural characterization of the mycobacterial siderophores is described. The genes so far identified as essential for iron acquisition and maintenance of an infection by pathogenic mycobacteria are discussed. The potential role of siderocalin in iron gathering by M. tuberculosis is featured. Because new drugs for M. tuberculosis are needed, this brief also emphasizes the design of antibiotics that interfere with siderophore biosynthesis and the use of siderophore analogs and/or conjugates.
  • 2010 Springer
    edited by Shlomo Yehuda, David I. Mostofsky.
  • 2012 Springer
    Gregory J. Anderson, Gordon D. McLaren, editors.
    Cellular iron metabolism -- Proteins of iron homeostasis -- Cellar iron physiology -- Regulation of iron metabolism in mammalian cells -- Concentrating, storing, and detoxifying iron: the ferritins and and hemosiderin -- Iron physiology -- Iron nutrition -- Intestinal iron absorption -- Plasma iron and iron delivery to the tissues -- Iron salvage pathways -- Molecular regulation of systemic iron metabolism -- Erythroid iron metabolism -- Iron and the reticuloendothelial system -- Iron and the immune system -- Disorders of iron homeostasis: anemias -- Iron deficiency -- Liabilities of iron deficiency -- Anemia of inflammation and chronic disease -- Disorders of red cell production and the iron-loading anemias -- Disorders of iron homeostasis: iron overload and related conditions -- Pathology of hepatic iron overload -- Hepatic pathobioogy of iron overload -- HFE-associated hereditary hemochromatosis -- Non-HFE hemochromatosis -- Miscellaneous iron-related disorders -- Iron and liver disease -- Neuropathology and iron: central nervous system iron homeostasis -- Iron metabolism in cancer and infection -- Clinical diagnosis and therapy -- Estimation of body iron stores -- Genetic testing for disorders of iron homeostasis -- Properties of therapeutically useful iron chelators -- Clinical use of iron chelators -- Model systems for studying iron homeostasis -- Mammalian models of iron homeostasis -- Yeast iron metabolism -- Zebrafish models of heme synthesis and iron metabolism.
  • 2013
    Douglas E. Hough.
    What is behavioral economics -- and why should we care? -- Keeping what we have, even if we don't like it -- Managing expectations and behavior -- Understanding the stubbornly inconsistent patient -- Understanding the stubbornly inconsistent consumer -- Understanding the medical decision making process, or, Why a physician can make the same mistakes as a patient -- Explaining the cumulative impact of physicians' decisions -- Can we use the concepts of behavioral economics to transform health care?
  • 2013 Wiley
    edited by Anton Emmanuel, Eamonn M.M. Quigley.
    This is packed with handy text tools like case histories, pitfall boxes and management algorithms, this attractive and convenient manual provides you with complete clinical guidance to irritable bowel syndrome (IBS), one of the most common GI conditions that doctors face daily. With contributions from the world's leading experts in IBS and edited by a stellar editor team, inside you'll find: A comprehensive symptom-specific approach to treatment options. Strong emphasis on the clinical care and management of patients. Exploration of the interface between primary and secondary care for IBS sufferers. Self-assessment MCQs to improve clinical skills. Examination of the overlap and difference between the USA and Europe in the management of IBS.
  • 2006 Springer
    Ai-Lean Chew, Ai-Lean, Howard Maibach (eds.).
    I. Classification and clinical features -- 1. Ten genotypes of irritant contact dermatitis -- 2. Irritant contact dermatitis versus allergic contact dermatitis -- II. Special clinical forms -- 3. Barrier function and perturbation: relevance for interdigital dermatitis -- 4. Friction melanosis -- 5. Diaper dermatitis -- 6. Chemical skin burns -- 7. Contact urticaria syndrome -- 8. Airborne irritant dermatitis -- 9. Irritant dermatitis of the scalp -- 10. Irritant contact dermatitis of the nails -- III. Epidemiology -- 11. Importance of irritant contact dermatitis in occupational skin disease -- 12. Irritant contact dermatitis in the tropics -- IV. Occupational irritant dermatitis -- 13. Occupational issues of irritant contact dermatitis -- 14. Hairdressing -- 15. Occupational irritant dermatitis - metal workers -- 16. Health care workers -- 17. The Electronics industry -- 18. Painters, lacquerers, and varnishers -- V. Risk factors for irritant dermatitis -- 19. Age -- 20. Gender -- 21. Ethnicity -- 22. Atopy -- VI. Insights from bioengineering -- 23. Prediction bioengineering -- 24. Quantitative sonography for the evaluation of irritant reactions -- 25. Functional skin testing: the SMART procedures -- 26. Bioengineering correlates of the sensitive skin syndrome: the sensory irritation component -- 27. Squamometry -- VII. The Irritants: special issues -- 28. Corrosive materials -- 29. Detergents -- 30. Sodium lauryl sulfate -- 31. Organic solvents -- 32. Oils, cutting fluids, and lubricants -- 33. Food -- 34. Dithranol -- 35. Copper -- 36. Fatty acid binding proteins -- VIII. Mechanisms of irritant dermatitis -- 37. Histopathology of irritant contact dermatitis -- 38. Percutaneous absorption and irritant dermatitis -- 39 Cytokines and irritant dermatitis -- 40. Oxidative stress -- 41. Langerhans cells and skin irritation -- 42. Hydration injury -- IX. Prevention of irritant dermatitis -- 43. Primary prevention of irritant contact dermatitis -- 44. Protective gloves -- 45. Anti-irritants -- 46. Barrier creams -- 47. Moisturizers -- 48. Moisturizers and irritant contact dermatitis -- 49. Effects of CO2 on barrier recovery -- X. Management and therapy -- 50. Treatment of irritant contact dermatitis -- 51. Topical corticosteroids in the treatment of irritant dermatitis -- 52. Barrier creams and emollients -- XI. Product testing -- 53. In vivo models of skin irritation -- 54. In vitro methods to predict skin irritation -- XII. Appendices -- 1. Questionnaire methods for hand dermatitis studies -- 2. Patient information sheets -- 3. Selected sources of information for irritant contact dermatitis.
    Also available: Print – 2006
  • 2014 Ovid
    [edited by] Richard S. Irwin, Craig M. Lilly, James M. Rippe.
  • 2008 Ovid
    editors, Richard S. Irwin, James M. Rippe.
    Also available: Print – 2008
  • 2011 Ovid
    editors, Richard S. Irwin, James M. Rippe.
  • 2011 Springer
    Antoine Suarez, Joachim Huarte, editors.
    Breakthrough in stem cell research? : the reprogramming of somatic cells to pluripotent stem cells / Boris Greber, Hans Schöler -- Preimplantation stages of human development : the biological and moral status of early embryos / Maureen L. Condic -- Complete moles and parthenotes are not organisms / Nicanor Pier Giorgio Austriaco -- Embryos grown in culture deserve the same moral status as embryos after implantation / Joachim Huarte, Antoine Suarez -- Distinguishing embryos from non-embryos / Patrick Lee -- On the status of human embryos and cellular entities produced through ANT : are they persons? / Pablo Requena Meana -- Does a human being have a right to life? : the debate on embryo research in Germany as a case study / Manfred Spieker -- Interspecies mixtures and the status of humanity / Neville Cobbe -- The boundaries of humanity : the ethics of human-animal chimeras in cloning and stem cell research / William B. Hurlbut -- Is this cell entity a human being? : neural activity, spiritual soul, and the status of the inner cell mass and pluripotent stem cells / Antoine Suarez.
  • 2009 Springer
    Maurice E. Langham.
    Ch. 1 "In vivo" manometric studies of the steady state intraocular pressure and the intraocular pressure pulse in animals and man -- Ch. 2 Rate of formation of the aqueous humor -- Ch. 3 Steady state intraocular pressure/flow relations in dead and living animal and human eyes -- Ch. 4 Homeostasis, autoregulation, and relative ischemia -- Ch. 5 Pressure/volume relation in eyes of dead and living animal and human eyes -- Ch. 6 Ocular perfusion pressure and its influence on the intraocular pressure pulse -- Ch. 7 Direct and indirect measurements of ocular blood flow in anesthetized and conscious animals and humans -- Ch. 8 Morphology and hydrodynamics of the chamber angle draining the aqueous humor -- Ch. 9 Sympathetic nerve innervation of the eye and the actions of the adrenergic neuron transmitter norepinephrine on intraocular pressure and ocular blood flow -- Ch. 10 Manometric studies on the intraocular pressure and vascular circulation in ophthalmic disease -- Ch. 11 Noninvasive studies on the IOP, PA and blood flow autoregulation in healthy and diseased eyes -- Ch. 12 Effect of posture and corneal thickness on the measurement of the intraocular pressure -- Ch. 13 The Langham pneumatic analogue and digitized tonometers -- Ch. 14 Calibration of the intraocular pressure and the intraocular pressure pulse using the Langham pneumatic tonometer -- Ch. 15 Theory of the Langham tonometer -- Ch. 16 Intraocular pressure/pulse amplitude relation in healthy animal and human eyes -- Ch. 17 Intraocular pressure/pulse amplitude relation and loss of autoregulation in ocular diseases -- Ch. 18 Autoregulation of the intraocular pressure and the ocular blood flow -- Ch. 19 Evaluation of ocular ischemia and the loss of autoregulation for the early detection of ocular vascular diseases -- Ch. 20 Action of drugs on ocular blood flow and on the intraocular pressure/pulse amplitude relation -- Ch. 21 Confluence and integration of therapies based on modulation of the intraocular pressure and ocular blood flow -- Ch. 22 Longitudinal therapeutic studies -- Ch. 23 Ophthalmodynamometry, the opthalmic arterial pressure and the effect of increased vascular resistance proximal and distal to the ophthalmic artery on ocular blood flow, the IOP/PA relation and vision -- Ch. 24 Ophthalmodynamometry -- Ch. 25 Autoregulation of the intraocular pressure and blood flow in the human eye -- Ch. 26 Objective measure of the diastolic and systolic ophthalmic arterial pressures -- Ch. 27 Ophthalmic arterial pressure in healthy subjects -- Ch. 28 Relation between the ophthalmic arterial pressure and the intraocular pressure/pulse amplitude relation -- Ch. 29 Modulation of the intraocular pressure/pulse amplitude relation in subjects with stenosis of the internal carotid artery -- Ch. 30 Alzheimer's disease and the eye -- Ch. 31 Ocular perfusion pressure and the visual threshold.
  • 2011 Springer
    Sohan Singh Hayreh.
    Structure of the Optic Nerve -- Blood Supply of the Optic Nerve -- Blood-Optic Nerve Barrier -- Factors Influencing the Optic Nerve Head Blood Flow -- Measurement of the Optic Nerve Head Blood Flow -- Terminology and Types of Ischemic Optic Neuropathy -- Optic Disc -- Clinical Evaluation of Patients with Ischemic Optic Neuropathies -- General Characteristics of Giant Cell Arteritis -- Clinical Features of Giant Cell Arteritis -- Diagnostic Criteria for Giant Cell Arteritis -- Ophthalmic Manifestations of Giant Cell Arteritis -- Management of Giant Cell Arteritis to Prevent Visual Loss -- Pathogenesis of Classical Non-arteritic Anterior Ischemic Optic Neuropathy -- Pathogenesis of Some Controversial Non-arteritic Anterior Ischemic Optic Neuropathy Clinical Entities -- Clinical Features of Non-arteritic Anterior Ischemic Optic Neuropathy -- Management of Non-arteritic Anterior Ischemic Optic Neuropathy -- Animal Model of Non-arteritic Anterior Ischemic Optic Neuropathy -- Classification and Incidence of Posterior Ischemic Optic Neuropathy -- Pathogenesis of Posterior Ischemic Optic Neuropathy -- Clinical Features of Posterior Ischemic Optic Neuropathy -- Management of Posterior Ischemic Optic Neuropathy.
  • 2016 Springer
    Bruce Ovbiagele, Tanya N. Turan, editors.
    Chapter 1 General Concepts: Management of Acute Ischemic Stroke -- Chapter 2 Pre-hospital Stroke Treatment (EMS stabilization protocols) -- Chapter 3 Intravenous Thrombolysis and Anti-thrombotics -- Chapter 4 Intra-Arterial Therapy for Acute Ischemic Stroke -- Chapter 5 Hemicraniectomy -- Chapter 6 Supportive Care and Management of In-hospital Complications -- Chapter 7 Post-Discharge Complications of Stroke -- Chapter 8 General Concepts: Stroke Mechanisms, Subtyping, and Work Up -- Chapter 9 Traditional Stroke Risk Factor Treatment -- Chapter 10 Heterogeneous causes of stroke -- Antithrombotics -- Chapter 11 Heterogeneous Causes of Stroke -- Select Emerging Risk Factors -- Chapter 12 Secondary Prevention After Cardioembolic Stroke -- Chapter 13 Secondary Prevention after Ischemic Lacunar Stroke -- Chapter 14 Secondary Prevention after Symptomatic Large Artery Extracranial Disease -- Chapter15 Secondary Prevention after Symptomatic Large Artery Intracranial Disease -- Chapter 16 Secondary Prevention after Non-atherosclerotic Cerebral Vasculopathies -- Chapter 17 Secondary Prevention after Ischemic Strokes due to Hypercoagulable States -- Chapter 18 General Concepts: Therapies for Rehabilitation and Recovery -- Chapter 19 Botulinum Toxin for Post-Stroke Limb Spasticity -- Chapter 20 Selective Serotonin Re-uptake Inhibitors -- Chapter 21 Constraint Induced Therapies -- Chapter 22 Virtual Reality in Stroke Rehabilitation -- Chapter 23 Transcranial Magnetic Stimulation -- Chapter 24 General Concepts: Management of Asymptomatic Cerebrovascular Disease -- Chapter 25 Asymptomatic Carotid Artery Stenosis -- Chapter 26 Subclinical Vascular Brain Injury -- Chapter 27 General Concepts: Stroke Systems of Care -- Chapter 28 Stroke Centers and Related Aspects of Stroke Systems -- Chapter 29 Role of Registries and Community Models in Developed Countries -- Chapter 30 Telemedicine in Stroke Systems of Care.
  • 2013
    Kenneth V. Iserson.
    Status: Not Checked OutLane Catalog Record
  • 2009 Springer
    Mohammed Salah Ben Ammar ; [préface de Louis Puybasset].
  • 2007 Springer
    Dariusch Atighetchi.
  • edited by Peter E. Pormann.
  • 2010 Springer
    Md. Shahidul Islam, editor.
    Also available: Print – 2010
  • 2012 Springer Protocols
    edited by Klaus Ballanyi.
    Autonomic nervous system in vitro : studying tonically active neurons controlling vagal outflow in rodent brainstem slices / Stefan Trapp and Klaus Ballanyi -- Anatomically "calibrated" isolated respiratory networks from newborn rodents / Araya Ruangkittisakul [and others] -- Physiological properties of human fetal cortex in vitro / Anna R. Moore [and others] -- Histological characterization of physiologically determined fast-spiking interneurons in slices of primate dorsolateral prefrontal cortex / Kenneth N. Fish [and others] -- Neural circuits underlying circadian oscillations in mammals : clocks in a dish / Takahiro J. Nakamura [and others] -- Osmoregulatory circuits in slices and en bloc preparations of rodent hypothalamus / Tevye J. Stachniak [and others] -- Establishing in vivo-like activity in rat cerebellar cells maintained in vitro / Bruce E. McKay [and others] -- Spontaneous rhythmic activity in the adult cerebral cortex in vitro / Maria V. Sanchez-Vives -- Living human brain slices : network analysis using voltage-sensitive dyes / Tilman Broicher and Erwin-Josef Speckmann -- Intact in vitro preparations of the neonatal rodent cortex : analysis of cellular properties and network activity / Heiko J. Luhmann and Werner Kilb -- Spontaneous neural network oscillations in hippocampus, cortex, and locus coeruleus of newborn rat and piglet brain slices / Chase Kantor [and others] -- Neuronal networks in the in vitro isolated guinea pig brain / Marco de Curtis [and others] -- Study of respiratory chemoreflexes using a novel dual-perfused rodent preparation / Trevor A. Day and Richard J.A. Wilson -- Defined medium organotypic cultures of spinal cord put 'pain in a dish' / James E. Biggs [and others] -- Rodent isolated spinal cord preparations to examine motor output / Sravan Mandadi [and others].
  • 2003 CRCnetBASE
    edited by Rajni Hatti-Kaul, Bo Mattiasson.
  • 2006
    Joshua Spanogle.
    Status: Not Checked OutLane Catalog Record
    The plot hinges on issues of medical ethics, infectious disease, and public safety.
  • 2012 Springer
    Lucyna Antkiewicz-Michaluk, Hans Rommelspacher, editors.
  • 2006 CRCnetBASE
    edited by Amnon Kohen, Hans-Heinrich Limbach.
  • 2012 Springer
    Hanudatta S. Atreya, editor.
    Also available: Print – 2012
  • 2016 ScienceDirect
    edited by Zvi Kelman.
    Application of natural isotopic abundance 1H-13C-and 1H-15N-correlated two-dimensional NMR for evaluation of the structure of protein therapeutics -- A semiautomated assignment protocol for methyl group side chains in large proteins -- 19F-site-specific-labeled nucleotides for nucleic acid structural analysis by NMR -- Applying thymine isostere 2,4-difluoro-5-methylbenzene as a NMR assignment tool and probe of homopyrimidine/homopurine tract structural dynamics -- Biomolecular deuteration for neutron structural biology and dynamics -- Dueterium labeling together with contrast variation small-angle neutron scattering suggests how skip captures and releases unfolded outer membrane proteins -- Deuteration in biological neutron reflectometry -- Deuterium labeling strategies for creating contrast in structure-function studies of model bacterial outer membranes using neutron reflectometry -- Essential strategies for revealing nanoscale protein dynamics by neutron spin echo spectoscopy -- Method for the determination of 15N incorporation percentage in labeled peptides and proteins -- QconCAT: internal standard for protein quantification -- Production purification, and characterization of 15N-labeled DNA repair proteins as internal standards for mass spectrometric measurements -- Hydrogen exchange mass spectrometry -- Mapping protein-ligand interactions with proteolytic fragmentation, hydrogen/deuterium exchange-mass spectrometry -- Isotope labelgin of biomolecules: structural analysis of viruses by HDX-MS.
  • 2015 ScienceDirect
    edited by Zvi Kelman.
    Isotope Labeling of Biomolecules - Labeling Methods, the latest volume of the Methods in Enzymology series contains comprehensive information on stable isotope labeling methods and applications for biomolecules.
  • 2007
    edited by Abby S. Bloch ... [et al.].
    Status: Not Checked OutLane Catalog Record
    An overview of the dietetics professional's training and opportunities in healthcare / Robert S. DeChicco and Laura E. Matarese -- Dietetics education: past, present, and future / Deborah D. Canter -- Advanced-level and specialty practice: how necessary or beneficial are they for practitioners? / Julie O'Sullivan Maillet and Wanda H. Howell -- The economics of dietetic patient care / Elvira Q. Johnson, Chris Biesemeier, and Sylvia Escott-Stump -- Development of the dietetics professional's role as a member of a healthcare team / Beth Leonberg -- Is the dietetics professional an equal player on the healthcare team? / Robert F. Kushner ... [et al.] -- Global dietetics issues / Patricia S. Anthony -- Nutrition screening in acute care / Pam Charney -- Nutrition assessment / Marion F. Winkler and Riva Touger-Decker -- Measuring nutrient intake: are the tools valid for clinical practice and/or research? / Phyllis J. Stumbo -- Conducting research in a clinical practice setting / Esther F. Myers -- Informatics in the new healthcare environment / Syed S. Haque -- Genetics, nutrituional genomics, and dietetics practice: what the dietetics professional should know / Gail P.A. Kauwell -- Hypertension and clinical nutrition practice / Jennifer Muir Bowers -- Nutrition and coronary artery disease / Wanda H. Howell -- Obesity: the challenge for the healthcare professional / Abby S. Bloch -- Nutritional approaches to diabetes mellitus / Judith Wylie-Rosett -- Emerging issues in cancer care and nutrition / Cynthia A. Thomson -- Food-drug interactions / June H. McDermott and Carol J. Rollins -- Issues with alternative/complementary nutrition therapies: their role in clinical practices / Diane Rigassio Radler and Adam Perlman -- Implementing nutrient-based recommendations and dietary guidelines / Ricardo Uauy and Abby S. Bloch -- Global nutrient recommendations and food-based dietary guidelines: tables / Abby S. Bloch.
  • 2014 Springer
    Helen E. Scharfman, Paul S. Buckmaster, editors.
    Part 1. How can we identify ictal and interictal abnormal activity? / Robert S. Fisher, Helen E. Scharfman, and Marco deCurtis -- What is the clinical relevance of in vitro epileptiform activity? / Uwe Heinemann and Kevin J. Staley -- What is the importance of abnormal "background" activity in seizure generation? / Richard J. Staba and Gregory A. Worrell -- What is a seizure focus? / J. Victor Nadler and Dennis D. Spencer -- What is a seizure network? Long-range network consequences of focal seizures / Hal Blumenfeld -- What is a seizure network? Very fast oscillations at the interface between normal and epileptic brain / Roger D. Traub, Mark O. Cunningham, and Miles A. Whittington -- Is there such a thing as "generalized" epilepsy? / Gilles van Luijtelaar, Charles Behr, and Massimo Avoli -- Part 2. Are there really "epileptogenic" mechanisms or only corruptions of "normal" plasticity? / Giuliano Avanzini, Patrick A. Forcelli, and Karen Gale -- When and how do seizures kill neurons, and is cell death relevant to epileptogenesis? / Ray Dingledine, Nicholas H. Varvel, and F. Edward Dudek -- How is homeostatic plasticity important in epilepsy? / John W. Swann and Jong M. Rho -- Is plasticity of GABAergic mechanisms relevant to epileptogenesis? / Helen E. Scharfman and Amy R. Brooks-Kayal -- Do structural changes in GABA neurons give rise to the epileptic state? / Carolyn R. Houser -- Does mossy fiber sprouting give rise to the epileptic state? / Paul S. Buckmaster -- Does brain inflammation mediate pathological outcomes in epilepsy? / Karen S. Wilcox and Annamaria Vezzani -- Are changes in synaptic function that underlie hyperexcitability responsible for seizure activity? / John G.R. Jefferys -- Does epilepsy cause a reversion to immature function? / Aristea S. Galanopoulou and Solomon L. Moshé -- Are alterations in transmitter receptor and ion channel expression responsible for epilepsies? / Kim L. Powell, Katarzyna Lukasiuk, Terence J. O'Brien, and Asla Pitkänen -- Part 3. How do we make models that are useful in understanding partial epilepsies? / David A. Prince -- Aligning animal models with clinical epilepsy: where to begin? / Stephen C. Harward and James O. McNamara -- What non-neuronal mechanisms should be studied to understand epileptic seizures? / Damir Janigro and Matthew C. Walker -- What epilepsy comorbidities are important to model in the laboratory? clinical perspectives / Simon Shorvon -- Epilepsy comorbidities: how can animal models help? / Carl E. Stafstrom -- What new modeling approaches will help us identify promising drug treatments? / Scott C. baraban and Wolfgang Löscher -- What are the arguments for and against rational therapy for epilepsy? / Melissa Barker-Haliski, Graeme J. Sills, and H. Steve White -- How can advances in epilepsy genetics lead to better treatments and cures? / Renzo Guerrini and Jeffrey Noebels -- How might novel technologies such as optogenetics lead to better treatments in epilepsy? / Esther Krook-Magnuson, Marco Ledri, Ivan Soltesz, and Merab Kokaia -- Index.
    Also available: Print – 2014
  • 2007 Karger
    editors, Carlo Agostoni, Oscar Brunser.
    Breastfeeding and complementary feeding of children up to 2 years of age / K.H. Brown -- Does breastfeeding protect from growth acceleration and later obesity? / A. Singhal -- Later effects of breastfeeding practice: the evidence / D. Turck -- Traditional foods vs. manufactured baby foods / E.L. Ferguson, N. Darmon -- Potential contaminants in the food chain: identification, prevention and issue management / F.P. Scanlan -- The microbiological risk / L. Morelli -- Cereal fortification programs in developing countries / S. Bulusu ... [et al.] -- Processed infant cereals as vehicles of functional components / M. Domelléf, C. West -- Functional ingredients in the complementary feeding period and long-term effects / C. Agostoni, E. Riva, M. Giovannini -- The influence of gluten: weaning recommendations for healthy children and children at risk for celiac disease / S. Guandalini -- Allergic infants: growth and implications while on exclusion diets / K. Laitinen, E. Isolauri -- Weaning infants with malnutrition, including HIV / N.W. Solomons -- Adverse effects of cow's milk in infants / E.E. Ziegler -- Whole cow's milk: why, what and when? / K.F. Michaelsen ... [et al.] -- Meat as an early complementary food for infants: implications for macro- and micronutrient intakes / N.F. Krebs -- Functional fermented milk products / O. Brunser, M. Gotteland, S. Cruchet.
  • 2001 HighWire
    edited by E.M. Antman and K.M. Fox, ICF co-chairs.
    Also available: Print – 2001
  • 2012
    Feng-Chiao Tsai.
    Terminating cell migration is critical for cancer treatment, because malignancy progresses through migrating tumor cells (metastasis) and migrating endothelial cells (neoangiogenesis.) Although cell migration requires Ca2+ for polarity and turning, it is not well understood how Ca2+ signals regulate cell migration. By studying sheet migration using endothelial cells loaded with Fura-2/AM, we identified pulsatile local Ca2+ pulses near the cell front. Each Ca2+ pulse controlled a local retraction and adhesion process in lamellipodia. Eliminating endogenous Ca2+ pulses reduced lamellipodial retraction while photo-release of Ca2+ from NP-EGTA induced front retraction and adhesion, indicating that these small Ca2+ signals were both necessary and sufficient for cyclic lamellipodia activity. Mechanistically, these local Ca2+ pulses acts through myosin light-chain kinase and myosin II to mediate actin cable retraction and to strengthen focal adhesion. We further explored the origin of these local Ca2+ signals. Removing extracellular Ca2+ did not eliminate local Ca2+ pulses, suggesting that these local signals are generated from activated inositol-3-phosphate receptors (IP3R) in the endoplasmic reticulum (ER). Inhibiting receptor tyrosine kinases (RTK) diminished local Ca2+ pulses, confirming that RTK-induced IP3R activation was the major source of these Ca2+ signals. More experiments demonstrated that diacylglycerol, the downstream regulator of RTK signaling, was also enriched in the cell front. It contributed to cell motility and polarity through protein kinase C. Therefore, polarized RTK signaling generates local Ca2+ signals and diacylglycerol in the cell front to ensure coordinated cell movement. We also investigated how Ca2+ homeostasis was maintained during cell migration. Our data showed that plasma membrane Ca2+ ATPases (PMCA) pumped Ca2+ out of the cell more actively in the front than in the back. The resulting low basal Ca2+ in the front of migrating cells maintained the sensitivity of the cell front to local Ca2+ pulses. Furthermore, to avoid depletion of Ca2+ in the front ER after it being released through IP3R, microtubules transported STIM1, a sensor of ER luminal Ca2+, toward the cell front triggering store-operated Ca2+ influx near the leading edge. Thus, cells maintain efficient migration through coordinated Ca2+ signaling systems. In summary, temporal-spatial coordination of Ca2+ signaling controls cell migration by regulating local adhesion, motility, and polarization. Our research also reveals the importance of interactions between signaling modules in migrating cells. Finally, a "synthetic immobility" screen will elucidate how different components are coordinated in cell migration, and will identify novel drug targets against cancer metastasis.
  • 2014 CRCnetBASE
    edited by E. Carstens and Tasuku Akiyama.
  • 2013
    Widya Mulyasasmita.
    The repair of damaged tissues through cell and growth factor administration is a promising strategy in regenerative medicine. However, clinical success has been limited due to the lack of effective delivery methods. While deemed minimally invasive, the conventional approach of direct injection in saline compromises the efficacy of the biological payloads. Post-injection cell survival is often dismally low, owing to the combination of shear forces during injection and hostile environments at the injury site. Growth factors delivered by bolus injections face rapid clearance and distribution to off-target sites, leading to suboptimal concentrations at the sites of therapy and potential side effects in normal tissues. These are major therapeutic hurdles because symptomatic relief following cell therapy is often correlated with the number of surviving donor cells. In the case of growth factor therapy, spatiotemporal control over growth factor distribution is critical for normal recovery, as tissue regeneration is a tightly coordinated process. This thesis presents a biomaterials approach to overcome these hurdles by harnessing polymer and protein engineering strategies to design injectable hydrogel carries for optimal cell and drug delivery. A broad survey of protein-engineered biomaterials is first given in Chapter 1 to provide a foundation for the design principles, synthesis, and characterization methods employed in subsequent chapters. Chapter 2 describes a mechanistic investigation into the physical forces imposed on cells during injection, using alginate polysaccharides as model carriers. This study reveals extensional stresses to be the dominant cause of cell death, and that cell viability can be restored by pre-encapsulation in hydrogel carriers that exhibit thixotropy, or the ability to shear-thin and self-heal. Subsequent chapters describe the design and characterization of a thixotropic protein-engineered hydrogel system called MITCH, or Mixing-Induced Two-Component Hydrogels, and their applications as cell and drug delivery vehicles in regenerative medicine. The crosslinking of the MITCH network relies on the reversible binding between complementary peptide domains, enabling gelation and cell encapsulation by simple mixing at physiological conditions. The design rationale and demonstration of thixotropy, cyto-compatibility, and three-dimensional cell encapsulation are discussed in Chapter 3. In Chapter 4, the specificity and stoichiometric precision of the peptide-peptide crosslinking interactions are highlighted as a distinguishing feature of MITCH. Polymer physics considerations are combined with protein science methodologies to enable the predictable tuning of macroscopic-level gel mechanics through molecular-level variations of component concentration and stoichiometric ratio. The remainder of the thesis focuses on the utility of the MITCH material as a delivery carrier for cell and drug regenerative therapy. Cell protection is demonstrated in Chapter 5, where adipose-derived stem cells injected subcutaneously in mice exhibit improved retention when encapsulated and delivered in MITCH, relative to saline and control biomatrices. Moreover, histological analyses of explants show endogenous cell invasion and signs of native extracellular matrix remodeling at day 3. The simple mixing protocol allows the encapsulation and release of peptide drugs and growth factors in their bioactive state. Chapter 6 describes the engineering of an affinity- and avidity-based peptide drug delivery system, developed by using the molecular recognition domains in MITCH. Fusion of angiogenic peptides to MITCH-specific affinity tags enables drug immobilization, sustained release, and prolonged local drug availability. This controlled release strategy induces higher levels of endothelial cell migration and matrix invasion compared to delivery from saline alone. Chapter 7 presents a therapeutic angiogenesis strategy by dual delivery of human induced stem cell-derived endothelial cells (hiPSC-ECs) and vascular endothelial growth factor (VEGF). This chapter also introduces MITCH 2.0, a new class of protein polymer/synthetic polymer hybrid hydrogel system created to improve tunability and ease of synthesis. Similar to the original version, MITCH 2.0 protects cells during injection and delivers drugs with tunable kinetics. In a murine hindlimb ischemia model, hiPSC-ECs co-delivered with VEGF in MITCH show improved post-transplantation viability and restore blood perfusion to the ischemic limb. All in all, by improving the delivery of cells and biochemical factors, the biomaterials work completed here provides enabling tools to advance other biological research endeavors, to ultimately realize the clinical translation and success of regenerative medicine.
  • 2009 Springer
    Ronald R. Gauch.
  • 2007 NLM
    prepared for publication by John H. Duffus, Monica Nordberg, Douglas M. Templeton.
  • 2005 Springer
    edited by M.D. Gilchrist.

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