Books

I

  • 2012
    Siddharth Taduri.
    The recent years have seen a tremendous growth in research and developments in science and technology, and an emphasis in obtaining Intellectual Property (IP) protection for one's innovations. Information pertaining to IP for science and technology is siloed into many diverse sources and consists of laws, regulations, patents, court litigations, scientific publications, and more. Although a great deal of legal and scientific information is now available online, the scattered distribution of the information, combined with the enormous sizes and complexities, makes any attempt to gather relevant IP-related information on a specific technology a daunting task. In this thesis, we develop a knowledge-based software framework to facilitate retrieval of patents and related information across multiple diverse and uncoordinated information sources in the US patent system. The document corpus covers issued US patents, court litigations, scientific publications, and patent file wrappers in the biomedical technology domain. A document repository is to be populated with issued US patents, court cases, scientific publications, and file wrappers in XML format. Parsers are developed to automatically download documents from the information sources. Additionally, the parser also extracts metadata and textual content from the downloaded documents and populates the XML repository. A text index is built over the repository using Apache Lucene, to facilitate search and retrieval of documents. Based on the document repository, the underlying methodology to search across multiple information sources in the patent system is discussed. The methodology is divided into two major parts. First, we develop a knowledge-based query expansion methodology to tackle domain terminological inconsistencies in the documents. Relevant knowledge is retrieved from external sources such as domain ontologies. Since our goal is to retrieve a collection of relevant documents across multiple sources, we develop a patent system ontology to provide interoperability between the different types of documents and to facilitate information integration. We discuss the Information Retrieval (IR) framework which combines the knowledge-based query expansion methodology with the patent system ontology to provide a multi-domain search methodology. A visualization tool based on term co-occurrence is developed that can be used to browse the document repository through class hierarchies of domain ontologies. The knowledge-based query expansion methodology is evaluated through formal measures such as precision and recall. A simple term-based search is used as a baseline reference for comparison. Additionally, the results from related works are also used for comparison. A series of common questions asked during patent prior art searches and infringement analysis are generated to evaluate the patent system ontology. A summary of the results and analysis is provided.
  • 2011 Springer
    Naakesh Dewan, John Luo, Nancy M. Lorenzi, editors.
    pt. 1. Overview -- pt. 2. Clinical practice issues -- pt. 3. Patient and client centric technologies section -- pt. 4. Organizational issues.
  • 2015 Springer
    Leonard Berliner, Heinz U. Lemke, editors.
    Preface -- Introduction -- The Digital Patient Model and Model Guided Therapy -- Hepatocellular Carcinoma and Patient Assessment -- Imaging in Hepatocellular Carcinoma: Radiologic Assessment -- Imaging in Hepatocellular Carcinoma: PET/CT -- Personalized Chemotherapy for Hepatocellular Carcinoma -- Surgical Treatment for Hepatocellular Carcinoma.- Minimally Invasive Therapies for Hepatocellular Cancer: Ablation Technologies -- Chapter 9 Minimally Invasive Therapies for Hepatocellular Cancer: Ablation Therapies -- Minimally Invasive Therapies for Hepatocellular Cancer:Catheter-Directed Therapies -- Radiation Oncology in the Treatment of Hepatocellular Carcinoma -- Design of an IT System for Hepatocellular Carcinoma -- Outlook and Expert Recommendations for Predictive, Preventive and Personalized Medicine and Hepatocellular Carcinoma.
  • 2013 Springer
    Stephen Goundrey-Smith.
    Over the last 30-40 years, information technology (IT) has revolutionized professional life for millions of people around the world. IT has reduced the need for bulk storage of paper records by organizations, has enabled automation of tasks that were previously repetitive and labor-intensive, and carry them out in a fast and accurate way, has enabled economies of scale, improved efficiencies and enabled new ways of working that were hitherto impossible. In parallel with the rise of IT during the last 40 years, the role of the pharmacist - and the society in which pharmacists work - has changed considerably. Pharmacists are no longer principally compounders of medicines, but they are still responsible for ensuring that the patient receives the correct medicine, ensuring that the patient understands why they should take their medicine, and helping the patient with taking the medicine and being concordant with therapy.Information Technology in Pharmacy: an Integrated Approach provides a concise and practical general introduction to pharmacy IT, discusses issues surrounding the adoption of technology and how technologies may be utlilized by the pharmacy profession to exercise new professional roles and achieve new professional aspirations. This book will be of prime interest to practicing pharmacists at all levels, pharmacy students and pharmacy educators, but also to health informaticians, hospital and health care system administrators.
  • 2006 Springer
    Krzysztof Zieliński, Mariusz Duplaga, David Ingram, editors.
  • 2008 Springer
    Andreas Kerren ... (ed.).
  • 2012 Cambridge
    Deborah Bowman, John Spicer, Rehana Iqbal.
    1. Introduction: why focus on informed consent? -- 2. Deciding who decides: capacity and consent -- 3. Putting the informed into 'informed consent': information and decision-making -- 4. Freedom of expression: the voluntary nature of consent -- 5. A patient's prerogative? The continuing nature of consent -- 6. Concluding words about consent -- Index.
  • 2015 Springer
    Jessica Minor.
    Introduction -- Predictive Genetic Testing -- The History and Components of Informed Consent -- Revised Model of Informed Consent -- Application of the Revised Model -- Conclusion.
  • 2015 Springer
    Mohsen El Kossi, Arif Khwaja, Meguid El Nahas, editors.
    Management of ADPKD -- Secondary Glomerular Disease Lupus Nephritis -- ANCA-Associated Vasculitis -- Acute Kidney Injury -- Chronic Kidney Disease -- Anaemia in Chronic Kidney Disease (CKD) -- Lipids and Chronic Kidney Disease -- Chronic Kidney Disease with Mineral and Bone Disorder (CKD-MBD) -- Diabetic Nephropathy -- Primary Glomerular Disease -- Hemodialysis -- Peritoneal Dialysis -- Transplantation.
  • 2005 NAP
  • 2010 IARC
    Ingested nitrate and nitrite -- 1. Exposure data -- 2. Studies of cancer in humans -- 3. Studies of cancer in experimental animals -- 4. Mechanistic and other relevant data -- 5. Summary of data reported -- 6. Evaluation and rationale -- -- Cyanobacterial peptide toxins -- 1. Exposure data -- 2. Studies of cancer in humans -- 3. Studies of cancer in experimental animals -- 4. Mechanistic and other relevant data -- 5. Summary of data reported -- 6. Evaluation and rationale
    Also available: Print – 2010
  • 2010 Springer
    Ramón Ribes, Pablo R. Ros ; presentazione dell'edizione italiana a cura di Pier Mannuccio Mannucci.
  • 2006 CRCnetBASE
    edited by Anilkuma G. Gaonkar, Andrew McPherson.
  • 2007
    edited by Anthony J. Hickey.
    Status: Not Checked OutLane Catalog Record
  • 2006 CRCnetBASE
    edited by Harry Salem, Sidney A. Katz.
    Also available: Print – 2006
  • 2015 CRCnetBASE
    edited by Harry Salem, Sidney A. Katz.
    Chapter 1. Collection and characterization of particulate matter deposition / Gregor Jereb, Sidney A. Katz, and Borut Poljésak -- chapter 2. Nose-only aerosol exposure systems : design, operation, and performance / Robert F. Phalen, Loyda B. Mendez, and Michael J. Oldham -- chapter 3. Lungs-on-a-chip / Shuichi Takayama, Joshua B. White, and Chao Zhang -- chapter 4. Human health risk assessment of inhaled materials / Rhian B. Cope, Patricia Nance, and Mike Dourson -- chapter 5. Application of inhalation toxicology concepts to risk and consequence assessments / Brian E. Hawkins, David J. Winkel, Patrick H. Wilson, and Ian C. Whittaker -- chapter 6. Time scaling of dose and time to response : the toxic load exponent / Juergen Pauluhn -- chapter 7. Improper use of Haber's Law results in erroneous fatality estimation from predictive models / Tom Ingersoll, Janet Moser, Douglas R. Sommerville, and Harry Salem -- chapter 8. Physiologically based kinetic modeling of inhalation / Harvey J. Clewell III, Jeffry D. Schroeter, and Melvin E. Andersen -- chapter 9. Nanomaterial inhalation exposure from nanotechnology-based consumer products / Yevgen Nazarenko, Paul J. Lioy, and Gediminas Mainelis -- chapter 10. Influence of physicochemical properties on the bioactivity of carbon nanotubes/nanofibers and metal oxide nanoparticles / Dale W. Porter and Vincent Castranova -- chapter 11. Inhalation toxicology of riot control agents / Harry Salem, Michael Feasel, and Bryan Ballantyne -- chapter 12. Incapacitating agents / Joseph L. Corriveau and Michael Feasel -- chapter 13. Exposure to ammonia / Finis Cavender and Glenn Milner -- chapter 14. Serpentine and amphibole asbestos / David M. Bernstein -- chapter 15. Pulmonary primary cells cocultured in a novel cell culture system, the integrated discrete multiple cell-type coculture system (IdMOC) : pulmonary cytotoxicity of eight cigarette smoke condensates and nicotine / Albert P. Li, Patricia Richter, Stephanie Cole, Janna Madren- Whalley, Jonathan Oyler, Russell Dorsey, and Harry Salem -- chapter 16. Animal models of chronic obstructive pulmonary disease (COPD) / Steven G. Kelsen -- chapter 17. Toxic inhalation injury : management and medical treatment / Arik Eisenkraft and Avshalom Falk -- Chapter 18. Transcriptomic responses to crystalline silica exposure / Pius Joseph, Christina Umbright, and Rajendran Sellamuthu -- chapter 19. Mechanisms involved in the inhalation toxicity of phosgene / Wenli Li and Juergen Pauluhn -- chapter 20. Chemical warfare agents and nuclear weapons / Terry J. Henderson, Nabil M. Elsayed, and Harry Salem -- chapter 21. Emergency response planning guidelines / Finis Cavender -- ch. 22. Safety assessment of therapeutic agents administered by the respiratory routes / Shayne C. Gad.
  • 2011 Springer
    C. Neal Ellis, editor.
    Obtaining and using genetic information -- Cancer and genetic counseling -- An ethos of genetic testing -- Hereditary breast cancer syndromes -- Gastrointestinal polyposis syndromes -- Familial colorectal cancer type X -- The familial atypical multiple mole melanoma (FAMMM)-pancreatic carcinoma (PC) syndrome -- Desmoid disease -- Hereditary nonpolyposis colorectal cancer -- Hereditary ovarian cancer and other gynecologic malignancies.
  • 2014 Springer
    Bernard Puech, Jean-Jacques De Laey, Graham E. Holder, editors.
    Introduction to Molecular Genetics and Genetic Testing for Retinal Dystrophies -- Electrophysiological Testing -- Dark Adaptation -- Fluorescein Angiography -- Indocyanine Green Angiography -- Fundus Autofluorescence Imaging in Retinal Dystrophies -- Spectral-Domain Optical Coherence Tomography in Hereditary Retinal Dystrophies -- Inherited Stationary Disorders of the Retina -- Retinitis Pigmentosa and Allied Disorders -- Leber Congenital Amaurosis and Early-Onset Retinal Dystrophy -- Retinitis Punctata Albescens -- Usher Syndromes -- Cone and Cone-Rod Dystrophies -- Enhanced S-Cone Syndrome -- Chorioretinopathies: Choroideraemia and Gyrate Atrophy -- Late-Onset Retinal Dystrophy (LORD) -- Stargardt Disease -- The Bestrophinopathies -- Retinal Dystrophies Associated with the PRPH2 Gene -- Alström Syndrome -- Bardet-Biedl Syndrome -- Cohen Syndrome -- Juvenile Neuronal Ceroid Lipofuscinoses (JNCL) -- Adult Refsum Disease (ARD) -- Abetalipoproteinemia -- LCHAD Deficiency -- Jalili Syndrome -- Spinocerebellar Ataxia 7 -- Dominant Cystoid Macular Dystrophy -- Autosomal Dominant Stargardt-Like Macular Dystrophy (ELOVL4) -- Spastic Paraplegia and Retinal Degeneration: Kjellin Syndrome -- Autosomal Dominant Drusen -- Cuticular Drusen -- Extensive Macular Atrophy with Pseudodrusen-Like Appearance -- Congenital Hypotrichosis with Juvenile Macular Dystrophy -- Mitochondrial Retinopathies -- Sorsby Fundus Dystrophy -- Bietti Crystalline Corneoretinal Dystrophy -- Cystinosis -- Primary Oxalosis -- Alport Syndrome -- X-Linked Retinoschisis -- Paramacular Choriocapillaris Atrophy -- Exudative Vitreoretinopathy -- Stickler Syndrome -- Wagner Syndrome -- Incontinentia Pigmenti Type II (IP2) -- Ganglion Cell Diseases -- Pseudoxanthoma Elasticum -- Aicardi Syndrome -- Microcephaly and Chorioretinopathy With or Without Mental Retardation and Lymphedema -- Alagille Syndrome -- Future Therapies for Retinitis Pigmentosa.
  • 2010 Springer
    Georg F. Hoffmann, Johannes Zschocke, William L. Nyhan, eds.
  • 2009 Springer
    Espinos, Carmen; Felipo, Vicente; Palau, Francesc.
    Pathology and diagnosis of muscular dystrophies / Carmen Navarro, Susana Teijeira, Beatriz San Millan.-- Standards of care for Duehenne muscular dystrophy: brief treat-NMD recommendations / Thomas Sejerson, Kate Bushby on behalf of the TREAT-EU Network of Excellence.-- Genetics and pahtogenesis of distal muscular dystrophies / Bjarne Udd.-- Phenotype variations in early onset Pompe disease: Diagnosis and treatment results with Myozyme [RTM] / Samuel Ignacio Pascual Pascual.-- Diseases of the human mitochondrial oxidative phosphorylation system / Julio Montoya, Ester Lopez-Gallardo, Maria Dolores Herrero-Martin, Inigo Martinze-Romero, Aurora Gomez-Duran, Daivd Pacheu, Magdalena Garreras, Carme Diez-Sanchez, Manuel J. Lopez-Perez, Eduardo Ruiz-Pesini.-- Mitochondrial diseases: a cross-talk between mitrochondrial and nuclear genomes / Antonella Spinazzola, Massimo Zeviani.-- Mitochondrial disorders due to nuclear OXPHOS gene defects / Cristina Ugalde, Maria Moran, Alberto Blazquez, Joaquin Arenas, Miguel A. Martin.-- Coenzyme Q10 deficiencies in neuromuscular diseases / Rafael Artuch, Leonardo Salviati, Sandra Jackson, Michio Hirano, Placido Navas.-- The role of mitochondrial network dynamics in the pathogenesis of Charcot-Marie-Tooth disease / Francese Palau, Anna Estela, David Pla-Martin, Maribel Sanchez-Piris.-- Pathogenesis and treatment of mitochondrial disorders / Salvatore DiMauro, Michio Hirano.-- Biology of peripheral inherited neuropathies: Schwann cell axonal interactions / Michael E. Shy.-- Phenotype and clinical evolution of Charcot-Marie-Tooth disease type 1A duplication / Jose Berciano, Antonio Garcia, Elena Gallardo, Cesar Ramon, Onofre Combarros.-- Genotypes & sensory pheotypes in 2 new X-linked neuropathies (CMTX3 and dSMAX) and dominant CMT/HMN overlap syndromes.-- Natural history and treatment of peripheral inherited neuropathies / Davide Pareyson, Chiara Marchesi.-- Spinal muscular atrophy during human development: where are the early pathogenic findings / Eduardo Tizzano.-- Spinal muscular atrophy / Jeremie Vitte, Ruben Attali, Nasim Warwar, Irena Gurt, Judith Melki.-- Friedreich ataxia: an update on animal models, frataxin function and therapies / Pilar Gonzalez-Cabo, Jose Vicente Llorens, Francesc Palau, Maria Dolores Molto.-- Genetics and pathogenesis of inherited ataxias and spastic paraplegias / Carmen Espinos, Francesc Palau.
    Also available: Print – 2009
  • 2007
    Laura L. Almstead.
    Status: Not Checked OutLane Catalog Record
  • 2011
    Kevin Shaoang Wei.
    1. VEGF inhibition increases hematocrit by hepatic Hif-2[Alpha]-dependent erythrocytosis and Hif-2[Alpha]--independent plasma volume contraction. Vascular Endothelial Growth Factor (VEGF) is an essential regulator of angiogenesis whose pharmacological inhibition represents a promising cancer therapeutic modality. We have previously reported that high-grade inhibition of VEGF by adenoviral expression of soluble VEGF receptor (VEGFR) ectodomains and recombinant VEGF Trap protein induce hepatic Epo-dependent erythrocytosis and polycythemia. Here, we demonstrate that VEGF inhibition induces erythrocytosis in a hepatic Hif-2[Alpha]-dependent manner. Conditional inactivation of hepatic Hif-2[Alpha] in Hif2[Alpha] flox/flox mice by either adenovirus Cre injection or albumin-Cre genetic cross suppressed VEGF inhibition-induced hepatic Epo production and blunted hematocrit elevation. Interestingly, a modest rise in hematocrit (5-10%) persisted in VEGF inhibitor-treated Hif-2[Alpha] liver knockout mice despite the absence of hepatic Epo elevation or reticulocytosis. Analysis of red blood cell mass and plasma volume indicate that, in addition to erythrocytosis, VEGF inhibition significantly reduces blood plasma volume (PV) (10-30% decrease) in a EPO- and Hif-2[Alpha]-independent manner. Thus, VEGF inhibition-induced hematocrit elevation in mice is attributable to both hepatic Hif-2[Alpha]-dependent erythrocytosis and Hif-2[Alpha] --independent plasma volume contraction, with accompanying implications for human patients exhibiting elevated haemoglobin levels in response to pharmacologic VEGF inhibition. 2. VEGF Inhibitors Enhance Hepatic insulin Signaling and Ameliorates Diabetes through Activation of Hepatic HIF-2[Alpha]. In the United States, over 18 million people have diabetes and approximately 90% of these cases are the type 2 form of the disease. The central pathophysiologic defect of T2DM is insulin resistance, where tissues such as muscle, fat and liver exhibit reduced responsiveness to insulin, despite normal to elevated levels of production of the hormone. During our studies on the role of vascular endothelial growth factor (VEGF) in erythropoeisis, we made a surprising observation that VEGF inhibition reduces blood glucose in normal lean mice and significantly corrects hyperglycemia in diabetic and insulin-resistant db/db mice. Metabolic profiling of VEGF inhibitor-treated mice revealed enhanced insulin sensitivity at the liver but not at the periphery. In the liver of these mice, expression of insulin receptor substrate-2 (IRS-2) was elevated, accompanied by enhanced Akt activation and suppression of gluconeogenic genes. Hepatic insulin sensitization by VEGF inhibitors requires hypoxia-inducible factor 2-alpha (Hif-2[Alpha]) as genetic deletion of hepatic Hif-2[Alpha] abrogated insulin sensitization and normalizes blood glucose in VEGF inhbitor-treated mice. Conversely, overexpression of a constitutively active allele of Hif-2[Alpha] in liver hepatocytes reduces blood glucose and activates hepatic insulin signaling in vitro and in vivo. Analysis of the human Irs-2 sequence revealed the presence of several potential Hypoxia-Responsive-Elements (HREs) within its 5' promoter. Using a Irs-2 promoter reporter construct, we found that overexpression of Hif-2[Alpha] or addition of a hypoxia-mimetic drug deferoxamine (DFO) resulted in increased Irs-2 transcription. These data suggest Irs-2 is a hypoxia-inducible gene. In this study, we show that VEGF inhibitors improve hepatic insulin action through activation of hepatic HIF-2[Alpha]. Our results suggest Hif-2[Alpha] positively regulates insulin signaling by promoting Irs-2 expression. These data suggest a previously unsuspected link between hypoxia and insulin signaling in the liver and indicate VEGF inhibitors may be useful for the treatment of diabetes.
  • 2007 CRCnetBASE
    edited by Paul J. Smith, Eddy W. Yue.
  • 2005 Springer
    contributors, D.R. Alexander ... [et al.] ; editors, Lorenzo A. Pinna and Patricia T.W. Cohen.
  • 2011 Springer
    Michael T. Bardo, Diana H. Fishbein, Richard Milich, editors.
    Part I: Introduction -- Part II: Neurobehavioral approaches for understanding inhibitory control -- Part III: Translating research on inhibitory control to at-risk populations -- PartIV: Translating research on inhibitory control to prevention interventions -- PartV: Conclusion.
  • 2013
    Liang Liang.
    Inhibition occurs throughout the nervous system and impacts diverse neuronal processes. In this dissertation, I focus on an inhibitory circuit motif in the Drosophila olfactory system, parallel inhibition, which differs from the classical feed-forward or feedback inhibition. The Drosophila excitatory and GABAergic inhibitory projection neurons (ePNs and iPNs) each receive input from antennal lobe glomeruli and send parallel output to the lateral horn, a higher-order brain center implicated in regulating innate olfactory behavior. By incorporating in vivo two-photon calcium imaging, advanced fly genetics and optogenetic methods to manipulate and record neuronal activity, we find that iPNs selectively suppress food-related odorant responses but spare signals from pheromone channel stimulation when using specific lateral horn neurons as an olfactory readout. Co-applying food odorant does not affect pheromone signal transmission, suggesting that the differential effects likely result from connection specificity of iPNs, rather than a generalized inhibitory tone. Calcium responses in the ePN axon terminals show no detectable suppression by iPNs, arguing against presynaptic inhibition as a primary mechanism. The parallel inhibition motif may provide specificity in inhibition to funnel specific olfactory information, such as food and pheromone, into distinct downstream circuits.
  • 2008 Springer
    Mark G. Darlison (ed.).
    Also available: Print – 2008
  • 2011 Springer
    Melanie A. Woodin, Arianna Maffei, editors.
    pt. 1. Refinement -- pt. 2. Addiction -- pt. 3. Pain and injury -- pt. 4. Learning and memory.
  • 2012 Wiley
    edited by Ian Wood, Michelle Garner.
    Initial assessment of the acute medical patient / Judith Morgan, Ian Wood -- Vulnerable adults / Louise Nelson ... [et al.] -- Sudden death / Sue Read, Jane Jervis -- Cardiac arrest / Carole Donaldson -- Shock / Judith Morgan, Ian Wood -- Altered consciousness / Ian Wood, Carole Donaldson -- Shortness of breath / Michelle Garner, Susan Hope, Ian Wood -- Chest pain / Michelle Garner -- Abdominal pain and upper gastrointestinal bleeding / Toni Jordan, Ruth Harris, Terry Wardle -- Extremity pain and swelling / Ian Wood.
  • 2011 ScienceDirect
    editied by Charles Silverstein.
    1. Introduction / Charles Silverstein -- 2. Scott's Interview (transcript) / Charles Silverstein -- 3. The initial psychotherapy interview / Charles Silverstein -- 4. Variations on gender and orientation in Scott's first interview / Margaret Nichols -- 5. Institutional aspects of the initial interview / Ronald E. Hellman -- 6. Death and bereavement / Michael C. Singer -- 7. An attachment perspective on the first interview (accelerated experiential dynamic psychotherapy) / Gil Tunnell -- 8. Understanding self-report of sexual abuse in an initial clinical interview / John C. Gonsiorek -- 9. Sex, drugs, and HIV (clinical issues and assessment strategies) / Peter S. Theodore -- 10. Motivational interviewing for health behavior problems / Donald Bux -- 11. Cognitive-behavioral therapy / DeMond M. Grant and LaRicka R. Wingate -- 12. Family systems (the relational contexts of individual symptoms) / Corinne Datchi-Phillips -- 13. Listening as a psychoanalyst / Ralph Roughton -- 14. Psychodrama (in searach of meaning through action) / Jacob Gershoni -- 15. Gay-affirmative psychotheraphy in real time (a first interview) / Armand R. Cerbone.
  • ScienceDirect
    edited by Jackie D. Corbin, Roger A. Johnson.
    Also available: Print – 1988
  • 2005 CRCnetBASE
    edited by Diane J. Burgess.
  • 2006 Springer
    [edited by] Mauricio de Maio, Berthold Rzany.
  • 2015 Springer
    Giuseppe Bergamini, Livio Presutti, Gabriele Molteni, editors.
    This well-illustrated book provides step-by-step guidance on the various techniques - microlaryngoscopic, fiberoptic endoscopic, and transcutaneous - that can be employed for the purpose of injection laryngoplasty, a surgical procedure in which a foreign material is injected into the vocal fold. The anatomy and function of the region are first explained, with identification of the causes and means of evaluation of glottic and neoglottic insufficiency. Advice is then provided on the choice of material for injection laryngoplasty, including absorbable and long-lasting options, on the basis of careful analysis that takes into account both the recent literature and the authors' own experiences. Detailed descriptions of the surgical indications and different procedures follow, and for ease of reference, clear flow charts on diagnosis and indications are also included. The book concludes with chapters on the use of injection laryngoplasty specifically in the pediatric population and on postoperative care and speech therapy following the procedure. Injection Laryngoplasty will provide valuable assistance to all surgeons wishing to perform this kind of surgery.
  • 2011 Springer
    Todd P. Stitik, editor.
    Basic principles of joint and soft tissue injection procedures -- Pharmacotherapy of joint and soft tissue injections -- Viscosupplementation -- Low back pain: considerations of when to refer patients for interventional spine procedures -- Administrative aspects of office-based injection procedures -- The shoulder -- The elbow -- The wrist -- The hand -- The hip -- The knee and its region -- The ankle and the foot.
  • 2015 Springer
    Michael D. McKee, Emil H. Schemitsch, editors.
    Chapter 1 Epidemiology and Definition of Chest Wall Injuries -- Chapter 2 A Review of Modern Literature -- Chapter 3 The Current Treatment of Flail Chest Injuries -- Chapter 4 The Pathophysiology of Flail Chest Injury -- Chapter 5 The Non-Operative Treatment of Flail Chest Injury -- Chapter 6 Biomechanics of Rib Fracture Fixation -- Chapter 7 Indications for Operative Fixation of Flail Chest Injuries -- Chapter 8 Surgical Approaches for Rib Fracture Applications -- Chapter 9 Principles of Plate Fixation: Rib Fracture Applications -- Chapter 10 Associated Intra-Thoracic Injuries and Their Treatment -- Chapter 11 Clinical Outcomes Following Operative Fixation of Flail Chest Injury -- Chapter 12 Complications of Surgical Treatment and Their Management -- Chapter 13 Post-Operative Care including Chest Tube Management -- Chapter 14 Long-Term Outcome Following Flail Chest Injuries -- Chapter 15 Management of Associated Fractures (Scapula, Clavicle) -- Chapter 16 Unstable Chest Wall Injuries: Future Directions.
  • 2007 ebrary
    Leon S. Robertson.
    Injury and the role of epidemiology -- Energy characteristics and control strategies -- Research objectives and usable data -- Injury severity -- Injury statistics -- National injury surveillance -- Local injury surveillance -- The use and abuse of causal analysis -- Research designs and data analysis -- Human factors -- Evaluation of programs to change human factors voluntarily -- Evaluation of laws and regulations directed at individual behavior -- Evaluation of agent, vehicle and environmental modifications -- Evaluation of post-injury treatment and rehabilitation -- Injury epidemiology and economics -- Summation of principles.
    Also available: Print – 2007
  • 2015
    Leon S. Robertson.
    Status: Not Checked OutLane Catalog Record
    Injury and the role of epidemiology -- Energy characteristics and control strategies -- Research objectives and usable data -- Injury severity -- Injury statistics -- National injury surveillance -- Local injury surveillance and risk factor surveys -- The use and abuse of causal analysis -- Research designs and data analysis -- Human factors -- Evaluation of programs to change human factors voluntarily -- Evaluation of laws and rules directed at individual behavior -- Evaluation of agent, vehicle and environmental modifications -- Evaluation of post-injury treatment and rehabilitation -- Injury epidemiology and economics -- Summation of principles.
  • 2016 Springer
    Dennis Caine, Laura Purcell, editors.
    Part I: Introduction -- The Exceptionality of the Young Athlete -- Part II: Epidemiology of Injury in Pediatric and Adolescent Sports -- Emergency Department Studies -- Epidemiology of Injury in Community Club and Youth Sport Organizations -- Epidemiology of Injury in High School Sports -- Epidemiology of Pediatric and Adolescent Injury in Adventure and Extreme Sports -- Epidemiology of Injury in Elite Youth Sports -- Part III: Overview of Common Injuries -- Overuse Injuries of the Extremities in Pediatric and Adolescent Sports -- Acute Lower Extremity Injuries in Pediatric and Adolescent Sports -- Acute Upper Extremity Injuries in Pediatric and Adolescent Sports -- Back Pain in the Young Athlete -- Part IV: Potentially Serious Injuries and Outcomes -- Concussion in Young Athletes -- Acute Catastrophic Injuries in High School Sports -- Psychological Injury in Pediatric and Adolescent Sports -- Part V: Injury Causation and Prevention -- Risk Factors for Injury in Pediatric and Adolescent Sports -- Injury Prevention in Youth Sports -- Part VI: Future Research in Pediatric and Adolescent Sports -- Injury Research in Pediatric and Adolescent Sports.
  • 2012 Springer
    Guohua Li, Susan P. Baker, editors.
  • 2012
    Lori Katherine Phillips.
    Stem cells and their derivatives, engineered in vitro prior to transplantation or patterned endogenously by the environment following transplant, are hailed for their promise in treating numerous diseases, from heart disease to diabetes and arthritis. However, one substantial barrier to the success of such treatments is the effect of the immunological response on survival and function of the cells. To this end, the transplantation of neural progenitor cells (NPCs) into the healthy brain provides one of the most favorable situations for graft survival, since the central nervous system is an immune privileged site and NPC are immune privileged cells. Herein, we address whether major histocompatibility complex (MHC) mismatch results in the rejection of NPC grafts placed in the murine hippocampus and investigate which immune effectors affect graft outcome. These transplantation studies reveal that while some allogeneic cells survive, MHC incompatibility strongly inhibits the differentiation and retention of graft-derived as well as endogenously produced new neurons. We also demonstrate that inhibiting innate immune activation with non-steroidal anti-inflammatory drugs decreases observed microglial activation and restores allogeneic neuron production and retention to levels seen in syngeneic grafts. Additionally, we show that MHC and activating ligand expression profiles on NPC facilitates recognition by Natural Killer (NK) cells. We utilize animals deficient for critical innate and adaptive immune receptors to establish that both NK cells and T cells influence graft survival and differentiation. Finally, we evaluate how MHC expression intrinsically influences NPC arborization in vitro. Intriguingly, MHC deficiency results in longer and more extensively branched processes. Taken together, our data suggest that MHC expression on grafted NPC facilitates NPC interaction with multiple other cell types, and consequently cannot be ignored when considering NPC transplantation clinically. Indeed, clinical application of NPC will undoubtedly place these cells into injured or diseased brains, where immune barriers may be more substantial. However, these data provide a starting point for evaluation of appropriate immune modulation strategies for such transplants.
  • 2008 Springer
    Eitan Yefenof, editor.
  • 2014 Springer Protocols
    edited by Hans-Joachim Anders, Adriana Migliorini.
    Detection of RNA modifications by HPLC analysis and competitive ELISA / Gernot Nees, Andreas Kaufmann, and Stefan Bauer -- Enzymatic synthesis and purification of a defined RIG-I ligand / Marion Goldeck ... [et al.] -- Crystallization of mouse RIG-I ATPase domain : in situ proteolysis / Filiz Civril and Karl-Peter Hopfner -- Isolation of RIG-I-associated RNAs from virus-infected cells / Andreas Schmidt ... [et al.] -- Structure modeling of Toll-Like Receptors / Jing Gong and Tiandi Wei -- Nucleic acid recognition in dendritic cells / Alexander Heiseke, Katharina Eisenächer, and Anne Krug -- Viral nucleic acid recognition in human nonimmune cells : in vitro systems / Andrea Ribeiro and Markus Wörnle -- Analysis of nucleic acid-induced nonimmune cell death in vitro / Simone Romoli and Adriana Migliorini -- In vitro analysis of nucleic acid recognition in B lymphocytes / Saskia Ziegler and Isabelle Bekeredjian-Ding -- Mapping of optimal CD8 T cell epitopes / Julia Roider, Thomas Vollbrecht, and Rika Draenert -- Modular approach to suppression assays : TLR ligands, conditioned medium, and viral infection / Viktor H. Koelzer and David Anz -- MicroRNA methodology : advances in miRNA technologies/ Theresa Kaeuferle ... [et al.] -- Expression profiling by real-time quantitative polymerase chain reaction (RT-qPCR) / Maciej Lech and Hans-Joachim Anders -- Evaluating the role of nucleic acid antigens in murine models of systemic lupus erythematosus / Amanda A. Watkins, Ramon G. B. Bonegio, and Ian R. Rifkin -- Induction and analysis of nephrotoxic serum nephritis in mice / John M. Hoppe and Volker Vielhauer -- Isolation of intratumoral leukocytes of TLR-stimulated tumor-bearing mice / Moritz Rapp, David Anz, and Max Schnurr -- Bifunctional siRNAs for tumor therapy / Fanny Matheis and Robert Besch.
  • 2013
    Yun Pei Sharon Goh.
    Eosinophil-derived IL-4 stimulates hepatocyte proliferation to promote liver regeneration Abstract It has been proposed that allergic immune responses, like those mediated by type 2 immunity, evolved to protect the host from damage caused by environmental challenges, including toxins, xenobiotics, and helminth infections (1, 2). Despite some support for this hypothesis (3, 4), the underlying mechanisms by which type 2 innate responses orchestrate the regeneration of injured tissues remain largely unknown. Here, we demonstrate a requirement for type 2 innate immunity in regeneration of liver after partial hepatectomy and toxin-mediated injury. Injury to liver results in rapid recruitment of eosinophils, which secrete IL-4 to promote the proliferation of quiescent hepatocytes. Surprisingly, signaling via the IL-4R[alpha] in macrophages, which have been implicated in tissue repair (3-5), is dispensable for hepatocyte proliferation and liver regrowth after injury. Instead, IL-4 exerts its mitogenic actions by directly activating IL-4R[alpha] in hepatocytes. Our findings have thus uncovered an unexpected mechanism by which allergic type 2 innate immunity stimulates hepatocyte proliferation to promote liver regeneration.
  • 2012 Springer
    Rong-Fu Wang, editor.
    "There has been major growth in understanding innate immune signaling, inflammation, immune suppression and cancer immunotherapy. Innate immune regulation and cancer immunotherapy highlights emerging research about the underlying mechanisms of innate immunity and signaling regulation, inflammation and immune suppression that promote or inhibit cancer development and progression, and offers novel ideas and strategies to develop therapeutic cancer drugs or cell therapy by manipulating or blocking these negative signaling pathways and generating potent antitumor immunity. Recent studies have identified key innate immune receptors or sensors, novel signaling molecules and immune regulatory molecules that control immune responses, inflammation and immune suppression in cancer and other diseases. Major progresses in understanding of tumor antigens, immune suppressive molecules and cell population and novel vaccine strategies bring therapeutic cancer vaccines and drugs in realty. With chapters written by internationally recognized contributors, this book provides essential introduction and guide for immunologists, basic, translational and clinical cancer researchers."--Publisher's website.
  • 2013
    Khoa Dinh Nguyen.
    Monophagocytes are a frontline defense against anything that should not be present in the body. Being highly mobile, they infiltrate almost every tissue to consume and dispose of material that might be damaging. To fight pathogens, monocytes and macrophages are transformed into pro-inflammatory machines that secrete catecholamines. However, monocytes and macrophages also exist in alternatively activated, anti-inflammatory forms that have a wide range of physiological roles. Unlike classically activated cells, which exhibit high pro-inflammatory potential, alternatively activated monocytes and macrophages (which are promoted by the TH2-type cytokines IL-4 and IL-13) are less pro-inflammatory and have distinct secretory and functional capacities. The inherent functional plasticity as well as the omnipresence of monocytes and macrophages in all tissues enables them to sense environmental changes. My dissertation will highlight two physiological settings in which, monocytes and macrophages, act as the sensors of perturbations in the environment to activate distinct physiological programs. The first part of my dissertation will discuss the role of adipose tissue alternatively activated macrophages in sensing changes in environmental temperature and its subsequent involvement in the maintenance of body temperature. The second part of my dissertation will provide evidences to show that inflammatory monocytes can sense change in the daily light dark cycle via their interaction with the circadian clock system to generate diurnal oscillation in monocyte-mediated inflammation.
  • 2008 Springer Protocols
    edited by Jonathan Ewbank and Eric Vivier.
    ENU mutagenesis in mice / Philippe Georgel ... [et al.] -- Innate immunity genes as candidate genes : searching for relevant natural polymorphisms in databases and assessing family-based association of polymorphisms with human diseases / Pascal Rihet -- KIR locus polymorphisms : genotyping and disease association analysis / Maureen P. Martin and Mary Carrington -- Experimental model for the study of the human immune system : production and monitoring of "human immune system" Rag2-/[gamma]c-/- mice / Nicolas Legrand, Kees Weijer, and Hergen Spits -- Bacterial artificial chromosome transgenesis through pronuclear injection of fertilized mouse oocytes / Kristina Vintersten ... [et al.] -- Bioluminescence imaging to evaluate infections and host response in vivo / Pamela Reilly Contag -- Intravital two-photon imaging of natural killer cells and dendritic cells in lymph nodes / Susanna Celli, Béatrice Breart, and Philippe Bousso -- Dissection of the antiviral NK cell response by MCMV mutants / Stipan Jonjic ... [et al.] -- Analyzing antibody-Fc-receptor interactions / Falk Nimmerjahn and Jeffrey V. Ravetch -- The isolation and identification of murine dendritic cell populations from lymphoid tissues and their production in culture / David Vremec and Ken Shortman -- Analysis of individual natural killer cell responses / Wayne M. Yokoyama and Sungjin Kim -- Isolation and analysis of human natural killer cell subsets / Guido Ferlazzo -- Innate immune function of eosinophils : from antiparasite to antitumor cells / Fanny Legrand ... [et al.] -- Ex vivo and in vitro primary mast cells / Michel Arock ... [et al.] -- Murine macrophages : a technical approach / Luisa Martinez-Pomares and Siamon Gordon -- Clinical analysis of dendritic cell subsets : the dendritogram / Anne Hosmalin, Miriam Lichtner, and Stéphanie Louis -- Clinical analysis of human natural killer cells / Pascale André and Nicolas Anfossi -- Lentiviral transduction of immune cells / Louise Swainson ... [et al.] -- Axenic mouse model / Antoine Giraud -- In vivo analysis of zebrafish innate immunity / Jean-Pierre Levraud ... [et al.] -- Reverse genetics analysis of antiparasitic responses in the malaria vector, Anopheles gambiae / Stephanie A. Blandin and Elena A. Levashina -- Drosophila immunity : methods for monitoring the activity of toll and Imd signaling pathways / Yves Romeo and Bruno Lemaitre -- Investigating the involvement of host factors involved in intracellular pathogen infection by RNAi in Drosophila cells / Hervé Agaisse -- Models of Caenorhabditis elegans infection by bacterial and fungal pathogens / Jennifer R. Powell and Frederick M. Ausubel -- Genetic analysis of Caenorhabditis elegans innate immunity / Michael Shapira and Man-Wah Tan -- Measuring cell-wall-based defenses and their effect on bacterial growth in Arabidopsis / Min Gab Kim and David Mackey.
  • 2013 Karger
    volume editors, Gunther Hartmann, Hermann Wagner.
    Microbiota's influence on immunity / Honda, K. ... [et al.] -- Inflammasomes and mucosal immune response / Elinav, E., Henao-Mejia, J., Flavell, R.A. -- Microbial endocrinology : an evolution-based shared mechanism determining microbiota's influence on health and disease / Lyte, M. -- Standing guard : innate lymphoid cells promote immunity and tissue homeostasis at barrier surface / Monticelli, L.A., Artis, D. -- miRNAs that shape the innate immune system : regulation through toll-like receptor signaling / Curtis, A.M., O'Neill, L.A. -- Type 2 diabetes and islet inflammation / Donath, M.Y. -- The innate immune system in Alzheimer's disease / Becker, H., Halle, A. -- Role of inflammasomes in obesity / Dixit, V.D. -- Gut-brain communication in the regulation of system metabolism / Miller, T.D., Pfliger, P.T., and Tschip, M.H. -- Metabolism and innate immunity : FOXO regulation of antimicrobial peptides in drosophila / Loch, G. ... [et al.] -- Dendritics cells orchestrate innate immunity agains bacterial kidney infection / Tittel, A.P. ... [et al.].
  • 2007
    guest editor: Adam Wanner.
  • 2008 Springer
    edited by Holger Heine.
    Evolution of resistance genes in plants / Shunyuan Xiao, Wenming Wang, Xiaohua Yang -- The path less explored: innate immune reactions in Cnidarians / Thomas C. G. Bosch -- Bug versus bug : humoral immune responses in Drosophila melanogaster / Deniz Ertürk-Hasdemir ... [et al.] -- Cellular immune responses in Drosophila melanogaster / Adrienne Ivory, Katherine Randle, Louisa Wu -- Immune reactions in the vertebrates' closest relatives, the urochordates / Konstantin Khalturin, Ulrich Kürn, Thomas C. G. Bosch -- Innate immune system of the zebrafish, Danio rerio / Con Sullivan, Carol H. Kim -- Toll-like receptors in the mammalian innate immune system / Andrei E. Medvedev, Stefanie N. Vogel -- NLRs : a cytosolic armory of microbial sensors linked to human diseases / Mathias Chamaillard -- Antimicrobial peptides as first-line effector molecules of the human innate immune system / Regine Gläser, Jürgen Harder, Jens-Michael Schröder -- The complement system in innate immunity / K. R. Mayilyan ... [et al.].
  • 2013 Springer
    Jeffrey M. Gidday, Miguel A. Perez-Pinzon, John H. Zhang, editors.
    Cerebral ischemia from cardiac arrest, stroke, and subarachnoid and intracerebral hemorrhage, together with trauma, epilepsy, and other CNS pathologies, continue to impose immense burdens of morbidity and mortality the world over. Despite many decades of research aimed at understanding the genetic and molecular basis of these pathologies, therapeutics developed on the basis of blocking 'known' injury mechanisms can actually claim few clinical successes. The field of CNS "preconditioning" was born from the preclinical finding more than 20 years ago that intentional activation of innate, cytoprotective factors could provide robust protection, or "tolerance" against cerebral ischemic injury. Herein, up-to-date summaries on all aspects of preconditioning for CNS disease, including the emerging topics of postconditioning and remote pre- and post-conditioning, are provided by the leading scientists in the field. The translational potential of both preclinical and clinical advances is underscored throughout, with the hope of accelerating the bench-to-bedside success of endogenous cytoprotection as a therapeutic strategy. Jeffrey M. Gidday PhD, Associate Professor of Neurosurgery at Washington University School of Medicine, has been working in the field of CNS preconditioning for 18 years, and has numerous publications on preconditioning-induced protection in the setting of several different cerebral and retinal pathologies. Miguel A. Perez-Pinzon PhD is Professor of Neurology/Neuroscience, Vice-Chair for Basic Science of Neurology at the University of Miami Miller School of Medicine. He began studies of ischemic preconditioning in 1995 and for many years prior to that worked in the field of anoxia tolerance, publishing close to 50 peer-reviewed articles and many book chapters on these topics. John H. Zhang MD PhD is Professor of Neurosurgery, Anesthesiology, and Physiology, and Vice-Chair of the Basic Science Department at the Loma Linda University School of Medicine. His research interests include stroke and medical gases, and he has published papers related to pre-, post- and remote-conditioning in subarachnoid hemorrhage, focal cerebral ischemia, and neonatal brain injury.
  • 2006 Springer
    W.L. Neuhuber ... [et al.].
  • 2015 Springer
    Roy Ahn, Thomas F. Burke, Anita M. McGahan, editors.
    Innovations to address specific populations and health -- Maternal health innovations and urbanization / Melody Eckardt, Hannah L. Harp, Roy Ahn, Genevieve Purcell, Emily de Redon, Rosemary Hines, and Thomas F. Burke -- Innovations in low- and middle-income countries for newborn and child health / Brett D. Nelson, Lisa B. Collins, and Edward W.J. Pritchard -- Addressing micronutrient malnutrition in urban settings / Laura A. Rowe and David M. Dodson -- Innovations to address specific urbanization-related threats to health -- Innovations in antihuman trafficking efforts : implications for urbanization and health / Roy Ahn, Genevieve Purcell, Anita M. McGahan, Hanni Stoklosa, Thomas F. Burke, Kathryn Conn, Hannah L. Harp, Emily de Redon, Griffin Flannery, and Wendy Macias Konstantopoulos -- Securing cities : innovations for the prevention of civic violence / Horacio R. Trujillo, Elena Siegel, Malcolm Clayton, Gabe Shapiro, and David Elam -- Disaster preparedness and response innovations : implications for urbanization and health / Laura Janneck and Paul Biddinger -- Innovations to address global drug counterfeiting : implications for urbanization and health / Kendra Amico, Emily Aaronson, and Howard Zucker -- Community noise, urbanization and global health : problems and solutions / Charles M. Salter, Roy Ahn, Faiza Yasin, Rosemary Hines, Laurence Kornfield, Ethan C. Salter, and Thomas F. Burke -- Modeling vulnerable urban populations in the global context of a changing climate / Vijay Lulla, Austin Stanforth, Natasha Prudent, Daniel Johnson, and George Luber -- Urbanization and unintentional Injury in low- and middle-income countries / John D. Kraemer -- Frameworks, cases and tools to address urbanization and health through innovation -- The Millennium Cities Initiative : an experiment in integrated urban development / Susan M. Blaustein -- Diagnostic innovations in developing urban settings / Patrick Beattie, Matthew Stewart, and Charles Mace -- Innovations in global health professional education : implications for urbanization / Leana S. Wen -- The case for comprehensive, integrated, and standardized measures of health in cities / Patricia L. McCarney and Anita M. McGahan.
  • 2012 Springer
    Luigi Bonavina, editor ; foreword by Tom R. DeMeester.
    Assessment of Surgical Innovation / Luigi Bonavina -- Clinical Impact of High-Resolution Manometry and Impedance-pH Monitoring / Marion Hädrich, Radu Tutuian -- Magnetic Augmentation of the Lower Esophageal Sphincter: Changing the Treatment Paradigm in Patients with Gastroesophageal Reflux Disease / Luigi Bonavina, Greta Saino, Davide Bona -- Transoral Esophageal Myotomy for Achalasia / Karl-Hermann Fuchs, Wolfram Breithaupt, Gábor Varga -- Radiofrequency Ablation and Antireflux Management for Non-dysplastic Barrett's Esophagus / Stephanie Fischer See, Sebastian F. Schoppmann -- Esophageal Preservation in Barrett's Esophagus with High-Grade Dysplasia and Mucosal Adenocarcinoma / Thomas J. Watson, Jeffrey H. Peters -- Cost-Effectiveness of Radiofrequency Ablation for Barrett's Esophagus / Francesca Rancati, Emanuele Meroni -- Vagal-Sparing Esophagectomy / Steven R. DeMeester -- Thoracoscopic Esophagectomy / Miguel A. Cuesta, Donald L. van der Peet -- Limited Versus Extended Lymphadenectomy / S. Michael Griffin, Shajahan Wahed -- Definitive Chemoradiation Therapy / Joel Shapiro M.D., J. Jan B. van Lanschot -- The Art and Science of Esophageal Anastomosis / Simon Law -- Rationale and Outcomes of the Kaizen Method Applied to Esophagectomy / Mark D. Iannettoni -- Perioperative Nutrition / Marco Braga -- Quality Assessment, Education and Training in Esophageal Surgery / Arnulf H. Hölscher, Ulrich K. Fetzner -- The Future of Esophageal Surgery / Tom R. DeMeester.
  • 2007
    Margaret L. Eaton and Donald Kennedy.
    Status: Not Checked OutLane Catalog Record
    Introduction : the need to ask questions about innovation -- Distinguishing innovative medical practice from research -- The modern history of human research ethics -- Innovation in the off-label use of drugs -- Innovative surgery -- Innovation in assisted reproduction -- Innovation in neuroimaging -- Questions, issues, and recommendations going forward -- Conclusion : final thoughts on the landscape of innovation.
  • 2012 Springer
    Selene Baschieri, editor.
    Prevention of infectious diseases by vaccination is one of the most significant achievements of modern medicine. During the 20th century, the average human life span in the developed world was about 70 years and it is expected to increase, with a significant portion of this increase directly attributed to vaccination. Since the first empiric vaccination trials, knowledge and technology have enormously evolved and new vaccination strategies are emerging on the market. Indeed, in spite of the great success, conventional vaccination strategies sometimes may result ineffective and, above all, may
  • 2013 Springer
    Lyle Berkowitz, Chris McCarthy, editors.
    The healing edge / Lyle Berkowitz and Chris McCarthy -- Mad for method / Chris McCarthy and Christi Dining Zuber -- section 1. You have an EHR: now what?!!?!. The inflection navigator / Lyle Berkowitz -- Making "right" easier / Peter Basch -- Prevention every time / James L. Holly -- Logic rules! / John W. Trudel and Lloyd D. Fisher -- "All or none" bundle philosophy / Thomas R. Graf -- Automatically getting better / David C. Stockwell and Brian R. Jacobs -- section 2. Meet you at 01100101. The connected patient / Jonathan S. Wald -- The virtual consult / Erin DeMarce Leff ... [et al.] -- TeleVisit keeps IT local / Ajay Sood ... [et al.] -- Mommy monitor / Steve Huffman and April R. Daugherty -- Every language now / David D. O'Neill, Susan Anthony, and Margaret Laws -- Rise of the ePharmacists / Mark S. Gagnon and Janell Moerer -- section 3. On the edge of edge. The smartest room / Tamra E. Minnier and David T. Sharbaugh -- One EMR to go please / Steve Flammini and James W. Noga -- Real-time, right care / Debra J. Hurd and Brian D. Patty -- Dashboards 2.0 / George Reynolds -- The patient voice amplified / Valerie M. Sue and Karen Tsang -- The gaming edge / Alex Tam, Vivian Distler, and Bradley Kreit.
  • 2016 Springer
    Seung-Kyu Han.
    1. Basics of wound healing -- 2. Interactive wound dressings -- 3. Biologic dermis graft -- 4. Tissue-engineered dermis graft -- 5. Atypical island flaps -- 6. Management of chronic wounds: with focus on diabetic ulcers -- 7. Infection, debridement, and biofilm -- 8. Negative-pressure wound therapy -- 9. Growth factor therapy -- 10. Cell therapy -- 11. Adjunctive therapy -- 12. Injectable tissue-engineered soft tissue.
  • 2009 Springer
    Bilge Sener, editor.
  • 2014 Springer
    Scott D. Rhodes, editor.
    HIV continues to be a profound challenge facing communities nationally and internationally. Until a vaccine or a cure is found, prevention remains a most crucial line of defense. However, the successes made to reduce exposure and transmission have not benefited all communities equally. HIV continues to affect vulnerable communities, and HIV-related health disparities are growing. The work documented in Innovations in HIV Prevention Research and Practice through Community Engagement spotlights the effectiveness of community involvement to reduce HIV infections in the United States. This timely resource introduces the concepts of community engagement, partnership, and community-based participatory research (CBPR). Contributors provide detailed examples of these concepts in which diverse research partners blend their unique insights and skills to arrive at an authentic understanding of phenomena and inform the translation of best practices and processes to enhance equity in HIV prevention and treatment. Equitable interactive collaboration is central to these efforts, in which community members and representatives from organizations, the scientific and medical sectors, and other relevant agencies nurture long-term health improvement through sustained teamwork. Challenges and barriers to effective engagement are identified, as are characteristics of successful partnerships. Included in the book: Details of a multigenerational HIV prevention intervention in a rural southeastern community. The challenges and successes of developing, implementing, and evaluating an intervention for higher-risk predominately heterosexual black men in college. The history of gay community involvement in HIV prevention and its contributions to the theory and current practice of engagement. Next steps in the integration of HIV-related policy change and research. Community engagement within American Indian communities. Keys to sustaining a CBPR partnership to prevent HIV within ethnic, sexual, and gender minority communities. Innovations in HIV Prevention Research and Practice through Community Engagement offers researchers and practitioners in public health, community health, and medicine guidance on community engagement that is both inspiring and realistic. 'Community engagement and knowledge continue to be essential to prevent HIV infections. This book is a compilation of the state-of-the-science of engagement and delves deeper into the meaning and utilization of community-based participatory research, with implications that reach beyond the HIV epidemic to public health and medicine in general.' - Laura C. Leviton, PhD, Senior Advisor for Evaluation, Robert Wood Johnson Foundation, Princeton, NJ
  • 2008 Springer
    M. Eisenmann-Klein, C. Neuhann-Lorenz (eds.).
  • 2005 Springer
    Patricia Solomon, Sue Baptiste, editors.
  • 2014 ScienceDirect
    Gerardo Caruso, Lucia Merlo, Maria Caffo.
  • 2008 Springer
    edited by Lev M. Berstein, Richard J. Santen.
    Also available: Print – 2008
  • 2006 IARC
    IARC Working Group on the Evaluation of Carcinogenic Risks to Humans.
    Also available: Print – 2006
  • 2013 WHO
    Sheffer, Marla.
    Also available: Print – 2013
  • 2009
    first draft prepared by Tiina Santonen ... [et al.].
  • 2005 CRCnetBASE
    Sangeeta, D.; LaGraff, John R.
  • ScienceDirect
    edited by Harry D. Peck, Jr., Jean LeGall.
    Also available: Print – 1994
  • 2006 Springer
    Paul Lecoq ... [et al.].
  • 2009 Springer Protocols
    edited by Christopher J. Barker.
    The role of inositol and the principles of labelling, extraction, and analysis of inositides in mammalian cells / Christopher J. Barker and Per-Olof Berggren -- HPLC separation of inositol polyphosphates / Christopher J. Barker, Christopher Illies, and Per-Olof Berggren -- Molecular manipulation and analysis of inositol phosphate and pyrophosphate levels in mammalian cells / James C. Otto and John D. York -- A femtomole-sensitivity mass assay for inositol hexakisphosphate / Andrew J. Letcher, Michael J. Schell, and Robin F. Irvine -- Synthesis of InsP₇ by the inositol hexakisphosphate kinase 1 (IP6K1) / Cristina Azevedo ... [et al.] -- Protein pyrophosphorylation by diphosphoinositol pentakisphosphate (InsP₇) / J. Kent Werner Jr., Traci Speed, and Rashna Bhandari -- Synthesis and nonradioactive micro-analysis of diphosphoinositol phosphates by HPLC with postcolumn complexometry / Hongying Lin, Karsten Lindner, and Georg W. Mayr -- Diphosphosinositol polyphosphates and energy metabolism : assay for ATP/ADP ratio / Andreas Nagel ... [et al.] -- Isolation of inositol 1,4,5-triphosphate receptor-associating proteins and selective knockdown using RNA interference / Akihiro Mizutani ... [et al.] -- Phosphoinositide-specific phospholipase C [beta]1 signal transduction in the nucleus / Roberta Fiume ... [et al.] -- Methods to assess changes in the pattern of nuclear phosphoinositides / Nullin Divecha -- Measurement of phosphoinositide 3-kinase products in cultured mammalian cells by HPLC / Frank T. Cooke -- Phosphoinositide analysis by liquid chromatography-mass spectrometry / Trevor R. Pettitt -- Imaging phosphoinositide dynamics in living cells / Anne Wuttke, Olof Idevall-Hagren, and Anders Tengholm.
  • 2003. ScienceDirect
    A. Kuksis.
    Also available: Print – 2003
  • 2012 ClinicalKey
    editor, W. Norman Scott.
    Online and in print, Insall & Scott Surgery of the Knee, edited by W. Norman Scott, MD, and 11 section editors who are experts in their fields, is your complete, multimedia guide to the most effective approaches for diagnosis and management of the full range of knee disorders affecting patients of all ages. From anatomical and biomechanical foundations, to revision total knee replacement, this authoritative reference provides the most up-to-date and complete guidance on cutting-edge surgical procedures, the largest collection of knee videos in one knee textbook. Expanded coverage and rigorous updates-including 40 online-only chapters-keep you current with the latest advances in cartilage repair and regeneration, allograft and autografts, computer robotics in total knee arthroplasty, and other timely topics. This edition is the first book ever endorsed by The Knee Society. Access the full text - including a wealth of detailed intraoperative photographs, a robust video library, additional online-only chapters, a glossary of TKR designs, quarterly updates, and more - at www.expertconsult.com. Get all you need to know about the clinical and basic science aspects of the full range of knee surgeries as well as the latest relevant information, including imaging and biomechanics; soft tissue cartilage; ligament/meniscal repair and reconstructions; partial and total joint replacement; fractures; tumors; and the arthritic knee. Master the nuances of each new technique through step-by-step instructions and beautiful, detailed line drawings, intraoperative photographs, and surgical videos. See exactly how it's done. Watch master surgeons perform Partial and Primary TKR, Revision TKR, Tumor Replacement, Fracture Treatment, and over 160 videos on the expertconsult.com. Find information quickly and easily thanks to a consistent, highly templated, and abundantly illustrated chapter format and streamlined text with many references and chapters appearing online only.
  • v. 1-2, 2006.
    [edited by] W. Norman Scott.
    Status: Not Checked OutLane Catalog Record
  • Google Books
    Blandford, George Fielding.
    Also available: Print – 1871.
  • 2016 Springer
    Gerald S. Pollack, Andrew C. Mason, Arthur N. Popper, Richard R. Fay, editors.
    Insect Hearing provides a broadly based view of the functions, mechanisms, and evolution of hearing in insects. With a single exception, the chapters focus on problems of hearing and their solutions, rather than being focused on particular taxa. The exception, hearing in Drosophila, serves as a case study of one of the most important model systems in neurobiology, including the neurobiology of hearing. Auditory systems, whether insect or vertebrate, must perform a number of basic tasks: capturing mechanical stimuli and transducing these into neural activity, representing the timing and frequency of sound signals, distinguishing between behaviorally relevant signals and other sounds and localizing sound sources. Studying how these are accomplished in insects offers a valuable comparative view that helps to reveal general principles of auditory function. · Introduction to Insect Acoustics by Andrew C. Mason and Gerald S. Pollack · Evolution of Acoustic Communication in Insects by Michael D. Greenfield · Behavioral Ecology of Insect Acoustic Communication by Rohini Balakrishnan · Hearing for Defense by Gerald S. Pollack · Vibrational Signaling by Jayne Yack · Mechanical Specializations of Insect Ears by James F. C. Windmill and Joseph C. Jackson · Auditory Transduction by Daniel F. Eberl, Azusa Kamikouchi, and Joerg T. Albert · Central Neural Processing of Sound Signals in Insects by Berthold Hedwig and Andreas Stumpner · Information Processing in the Auditory Pathway of Insects by Bernhard Ronacher · Hearing in Drosophila by Azusa Kamikouchi and Yuki Ishikawa About the Editors: Gerald Pollack is a Professor Emeritus in the Department of Biology at McGill University. Andrew Mason is Associate Professor & Chair in the Department of Biological Sciences at the University of Toronto, Scarborough. Richard R. Fay is Distinguished Research Professor of Psychology at Loyola University Chicago. Arthur N. Popper is Professor Emeritus and Research Professor in the Department of Biology at the University of Maryland, College Park. About the Series: The Springer Handbook of Auditory Research presents a series of synthetic reviews of fundamental topics dealing with auditory systems. Each volume is independent and authoritative; taken as a set, this series is the definitive resource in the field.
  • 2010 Springer
    edited by Steeve Hervé Thany.
    Identification of cholinergic synaptic transmission in the insect nervous system / Steeve Hervé Thany, Hélène Tricoire-Leignel, and Bruno Lapied -- The evolution of pentameric ligand-gated ion channels / Joseph A. Dent -- Diversity of insect nicotinic acetylcholine receptor subunits / Andrew K. Jones and David B. Sattelle -- Identification of critical elements determining toxins and insecticide affinity, ligand binding domains, and channel properties / Hélène Tricoire-Leignel and Steeve Hervé Thany -- Electrophysiological studies and pharmacological properties of insect native nicotinic acetylcholine receptors / Steeve Hervé Thany -- Characterisation of insect nicotinic acetylcholine receptors by heterologous expression / Neil S. Millar and Stuart J. Lansdell -- Neonicotinoid insecticides : historical evolution and resistance mechanisms / Steeve Hervé Thany -- Ecotoxicity of neonicotinoid insecticides to bees / Axel Decourtye and James Devillers -- State of the art on insect nicotinic acetylcholine receptor function in learning and memory / Monique Gauthier.
    Also available: Print – 2010
  • 2000- NCBI Bookshelf
    [Institut National de la Santé et de la Recherche Médicale].
    A collection of syntheses of the international scientific literature and recommendations on public health problems, by Inserm's expert advisory groups.
  • 2011 Springer
    Adam J. Dupuy, David A. Largaespada, editors.
    1. Insertional Mutagenesis: A Powerful Tool in Cancer Research -- 2. Retroviral Insertional Mutagenesis in Mouse Models of Leukemia and Lymphoma -- 3. Gene Discovery by MMTV Mediated Insertional Mutagenesis -- 4. Chicken Models of Retroviral Insertional Mutagenesis -- 5. Sleeping Beauty Models of Cancer -- 6. Insertional Mutagenesis in Hematopoietic Cells: Lessons Learned from Adverse Events in Clinical Gene Therapy Trials -- 7. Bioinformatics of High-Throughput Insertional Mutagenesis -- Index.
  • 2013 CRCnetBASE
    Tony Fleming.
    1. Introduction -- 2. Self-field theory -- 3. Biological and cosmological evolution -- 4. Biophotons and diffusion in biology -- 5. Cell division and membrane diffusion -- 6. Electromagnetic and acoustic-based therapies.
  • 2014 Springer
    Christine Koppl, Geoffrey A. Manley, Arthur N. Popper, Richard R. Fay, editors.
    The hearing organs of non-mammals, which show quite large and systematic differences to each other and to those of mammals, provide an invaluable basis for comparisons of structure and function. By taking advantage of the vast diversity of possible study organisms provided by the "library" that is biological diversity, it is possible to learn how complex functions are realized in the inner ear through the evolution of specific structural, cellular and molecular configurations. Insights from Comparative Hearing Research brings together some of the most exciting comparative research on hearing and shows how this work has profoundly impacted our understanding of hearing in all vertebrates.
  • 2009
    Relly Brandman.
    Status: Not Checked OutLane Catalog Record
  • 2006 Springer
    M. Conn, C. Kordon, Y. Christen (eds.).
  • 2015 Springer Protocols
    edited by Elena García-Fruitós.
    General introduction : recombinant protein production and purification of insoluble proteins / Neus Ferrer-Miralles ... [et al.] -- Overcoming the solubility problem in E. coli : available approaches for recombinant protein production / Agustín Correa and Pablo Oppezzo -- Optimization of culture parameters and novel strategies to improve protein solubility / Ranjana Arya ... [et al.] -- Cleavable self-aggregating tags (cSAT) for protein expression and purification / Zhanglin Lin ... [et al.] -- Beyond the cytoplasm of Escherichia coli : localizing recombinant proteins where you want them / Jason T. Boock ... [et al.] -- Characterization of amyloid-like properties in bacterial intracellular aggregates / Anna Villar-Pique, Susanna Navarro, and Salvador Ventura -- Co-translational stabilization of insoluble proteins in cell- free expression systems / Lei Kai ... [et al.] -- Functional expression of plant membrane proteins in Lactococcus lactis / Sylvain Boutigny .... [et al.] -- High cell-density expression system : yeast cells in a phalanx efficiently produce a certain range of "Difficult-to-Express" secretory recombinant proteins / Yasuaki Kawarasaki, Takeshi Kurose, and Keisuke Ito -- Insect cells-baculovirus system for the production of difficult to express proteins / Judit Osz-Papai ... [et al.] -- Transient expression in HEK 293 cells : an alternative to E. coli for the production of secreted and intracellular mammalian proteins / Joanne E. Nettleship ... [et al.] -- Recombinant glycoprotein production in human cell lines / Kamilla Swiech ... [et al.] -- Soluble recombinant protein production in Pseudoalteromonas haloplanktis TAC125 / Maria Giuliani ... [et al.] -- Screening methodology for purifying proteins with aggregation problems / Mario Lebendiker, Michal Maes, and Assaf Friedler -- Solubilization and refolding of inclusion body proteins / Anupam Singh, Vaibhav Upadhyay, and Amulya K. Panda -- Bacterial inclusion body purification / Joaquin Seras-Franzoso ... [et al.] -- Characterization of intracellular aggresomes by fluorescent microscopy / Lianwu Fu and Elizabeth Sztul -- Dialysis : a characterization method of aggregation tendency / Mireia Pesarrodona, Ugutz Unzueta, and Esther Vázquez -- Applications of mass spectrometry to the study of protein aggregation / Sílvia Bronsoms and Sebastián A. Trejo -- Insoluble protein assemblies characterized by Fourier transform infrared spectroscopy / Antonino Natalello and Silvia M. Doglia -- Insoluble protein characterization by circular dichroism (CD) spectroscopy and nuclear magnetic resonance (NMR) / Shaveta Goyal ... [et al.] -- Methods for characterization of protein aggregates / Witold Tatkiewicz ... [et al.] -- Predicting the solubility of recombinant proteins in Escherichia coli / Roger G. Harrison and Miguel J. Bagajewicz -- Insoluble protein applications : the use of bacterial inclusion bodies as biocatalysts / Eva Hrabárová , Lucia Achbergerová , and Jozef Nahálka.
  • 2010 Springer
    Colleen E. Carney, Jack D. Edinger.
    Insomnia is often undiagnosed, or treated as a symptom of anxiety. This is the first guidebook for clinicians that considers the evaluation and management of insomnia and related sleep disturbances that occur conjointly with the common anxiety disorders.
  • v. 1, 1986.
    McCartor, Robert L.; Tyner, G. S.
    Status: Not Checked OutLane Catalog Record
    v. 1. Eye of the storm / Robert L. McCartor and George S. Tyner.
  • 2017 ClinicalKey
    Theodore X. O'Connell.
  • 2009 ClinicalKey
    Theodore X. O'Connell, Kathleen Dor.
    This book is a portable pocket resource and quick refresher that helps you develop and refine your diagnostic skills. Practical and easy to use, it provides clear workup plans for the most common obstetric and gynecologic conditions, providing you with quick, focused guidance with the flexibility to adapt to each unique patient. Topics are organized alphabetically and cover the signs, symptoms, and abnormal lab readings for each condition. Replace information taken from memory or multiple references with one concise, indispensable book so you can make accurate diagnoses in less time! Covers the most commonly encountered obstetric and gynecologic conditions to provide you with a practical and useful manual for daily practice. Reflects how a patient actually presents by organizing alphabetically by presenting sign, symptom, or lab abnormality. Includes a brief background discussion on each topic, followed by lists of important related materials (such as medications that may contribute to each condition) and laboratory and/or radiographic tests to be ordered. Describes each diagnostic test so you can refresh or familiarize yourself with the purpose of the test. Provides a sound framework for building your workups using detailed treatment algorithms.
  • 2010 ClinicalKey
    Theodore X. O'Connell [and others].
    Instant Workups: Clinical Guide to Pediatrics, by Theodore X. O'Connell, MD, is a portable pocket resource and quick refresher that helps you develop and refine your diagnostic skills. Practical and easy to use, it provides clear workup plans for the most common pediatric conditions, providing you with quick, focused guidance with the flexibility to adapt to each unique patient. Topics are organized alphabetically and cover the signs, symptoms, and abnormal lab readings for each condition. Replace information taken from memory or multiple references with one concise, indispensable book so you can make accurate diagnoses in less time! Covers the most commonly encountered pediatric conditions to provide you with a practical and useful manual for daily practice. Reflects how a patient actually presents with an organization by presenting sign, symptom, or lab abnormality. Includes a brief background discussion on each topic, followed by lists of important related materials (such as medications that may contribute to each condition) and laboratory and/or radiographic tests to be ordered. Describes each diagnostic test so you can refresh or familiarize yourself with the purpose of the test. Provides a sound framework for building a workup with algorithms for each topic.
  • NAP
    Committee on the Role of Institutional Review Boards in Health Services Research Data Privacy Protection, Division of Health Care Services, Institute of Medicine.
  • Google Books
    Also available: Print – 1956-
  • 2012 ClinicalKey
    Marc R. Safran, James Zachazewski, David A. Stone ; with contributions by Anthony J. Saglimbeni.
  • 1. Getting started -- 2. Instrument control session -- 3. Using interface objects -- 4. Controlling instruments using GPIB -- 5. Controlling instruments using VISA -- 6. Controlling instruments using the serial port -- 7. Controlling instruments using TCP/IP and UDP -- 8. Using device objects -- 9. Using VXIplug&play drivers -- 10. Using IVI drivers -- 11. Using generic instrument drivers -- 12. Saving and loading the session -- 13. Test & measurement tool -- 14. Using the instrument driver editor -- 15. Using the instrument driver testing tool -- 16. Using the Instrument Control Toolbox block library -- A. Vendor driver requirements and limitations.
  • 2006 CRCnetBASE
    Terry Mills, III, James Conrad Roberson, Christian C. Matchett, Mathew J. Simon, Mark D. Burns, Robert J. Ollis, Jr.
    V. 1. Acebutolol -- Dapsone -- v. 2. Dauromycin -- Indigotin Disulfonate -- v. 3. Indole-3-Acetic Acid -- Phendimetrazine -- v. 4. Phenelzine -- Zoxazolamine -- v. 5. Raman spectra data -- Mass spectra of pesticides -- Mass spectra of derivatized drugs -- Gas chromatography/infrared spectra of drugs -- v. 6. Standard KBr infrared spectra and standard NMR solvent spectra -- Supplemental infrared spectra -- Supplemental NMR spectra -- Ultraviolet absorption maxima -- Infrared index -- Mass spectra indices of drugs -- Mass spectra indices of pesticides -- Molecular formula index -- Gas chromatographic data -- Index to specific compounds.
  • 2007
    Shirley M. Tighe.
    Status: Not Checked OutLane Catalog Record
    Instrument preparation for surgery -- General Surgery -- Female Reproductive Surgery -- Genitourinary surgery -- Orthopedic surgery -- Eye, ear, nose, and throat surgery -- Oral, maxillary, and facial surgery -- Plastic surgery -- Peripheral vascular, cardiovascular, and thoracic surgery -- pediatric surgery -- Neurosurgery.
  • 2006 Springer
    [edited by] Alexandre Mebazaa, Didier Payen.
  • 2011 Springer
    I. George Fantus, editor.
    Insulin and the Physiology of Carbohydrate Metabolism -- Insulin/IGF-1 Signaling Nodes and their Role in Carcinogenesis -- The Mechanisms and Impact of Obesity and Insulin Resistance on Breast Cancer Incidence -- Obesity and Cancer: Epidemiology -- Insulin, Insulin Resistance, and Cancer Associations -- Animal Models of Hyperinsulinemia, Insulin Resistance, and Cancer -- Potential Mechanisms Linking Insulin to Cancer -- Actions of Insulin As a Survival and Growth Factor: Akt, mTOR, and Regulation of Translation -- AMP-Activated Protein Kinase and Cancer Cell Metabolism -- The Role of the IGF Axis in Human Malignancy: Evidence from Epidemiological Studies and Tissue Analysis -- IGF-I and Insulin Receptor Families in Cancer -- Insulin Resistance: Clinical Implications for Cancer Treatment and Prevention.
  • 2007 Springer
    edited by Evanthia Diamanti-Kandarakis, John E. Nestler, Dimitrios Panidis, Renato Pasquali.
    1. Evaluation for insulin resistance and comorbidities related to insulin resistance in polycystic ovary syndrome / Ricardo Azziz -- 2. Fat distribution and adipose products in polycystic ovary syndrome / Enrico Carmina -- 3. Treatment of infertility in polycystic ovary syndrome: ovulation induction / Deborah S. Wachs and R. Jeffery Chang -- 4. Imaging studies in polycystic ovary syndrome / Sophie Jonard,Yann Robert, Yves Ardaens, and Didier Dewailly -- 5. Genes related to metabolic abnormalities or insulin resistance in polycystic ovary syndrome / Hector F. Escobar-Morreale -- 6. Anti-androgens / Kiirşad Ünlühizarci and Fahrettin Keleştimur -- 7. Lipid abnormalities in polycystic ovary syndrome / Djuro Macut -- 8. Serine phosphorylation, insulin resistance, and the regulation of androgen synthesis / Andrew A. Bremer and Walter L. Miller -- 9. Chronic treatment of polycystic ovary syndrome: oral contraceptive pills / Shahla Nader -- 10. Insulin-sensitizing drugs for the treatment of infertility in polycystic ovary syndrome / Cynthia S. Ryan and John E. Nestler -- 11. Diet and lifestyle factors in the etiology and management of polycystic ovary syndrome / R.J. Norman and L.J. Moran -- 12. Adrenarche: the interrelationship of androgens/insulin on the development of the metabolic syndrome/polycystic ovary syndrome / Sharon E. Oberfield, Natasha Leibel, Lauren Antler, Miriam Silfen, Lenore S. Levine, Mary Horlick, Goldy Carbunaru, Ximena Lopez, and Songya Pang -- 13. Cardiovascular disease and inflammation / Francesco Orio, Jr., Evanthia Diamanti-Kandarakis, and Stefano Palomba -- 14. Surgery and laser diathermy / Stefano Palomba, Fulvio Zullo, Evanthia Diamanti-Kandarakis, and Francesco Orio, Jr. -- 15. Late pregnancy complications in polycystic ovary syndrome / Dimitrios Panidis and Neoklis A. Georgopoulos -- 16. Glucose intolerance / Vincenzo Toscano -- 16. Hormonal and biochemical evaluation of polycystic ovary syndrome / Bulent O. Yildiz -- 18. Endometrial carcinoma in polycystic ovary syndrome / Emmanuel Diakomanolis -- 19. Statins, oxidative stress, and polycystic ovary syndrome / Pinar H. Kodaman and Antoni J. Duleba -- 20. Glucose intolerance in polycystic ovary syndrome: focus on the [beta]-cell / David A. Ehrmann -- 21. Polycystic ovary syndrome: definitions and epidemiology / Bart C.J.M. Fauser, Frank J. Broekmans, Joop S.E. Laven, Nick S. Macklon, and Basil Tarlatzis -- 22. Anovulation in polycystic ovary syndrome / Steven Franks -- 23. Nonalcoholic fatty liver disease in polycystic overy syndrome / WalterFutterweit -- 24. "Secondary" polycystic ovary syndrome / Gregory Kaltsas and George Chrousos -- 25. Long-term sequelae of polycystic ovary syndrome: association with insulin resistance and the metabolic syndrome / Richard S. Legro -- 26. The Insulin resistance of polycystic ovary syndrome / Marek Demissie, Richard S. Legro, and Andrea Dunaif -- 27. Therapeutic aspects of polycystic ovary syndrome in adolescence / George Mastorakos, Carolina Koliopoulos, and George Creatsas -- 28. Lifestyle intervention in polycystic ovarian syndrome / Onno E. Janssen, Susanne Tan, and Susanne Hahn -- 29. Involvement of the endocannabinoid system in metabolism and fertility: potential implication in the polycystic ovary syndrome / Uberto Pagotto, Alessandra Gambineri, Valentina Vicennati, and Renato Pasquali -- 30. Insulin resistance: definition and epidemiology in normal women and polycystic ovary syndrome women / Renato Pasquali and Alessandra Gambineri -- 31. Clinical evaluation of polycystic ovary syndrome / Ann E. Taylor -- 32. Pharmaceutical intervention in metabolic and cardiovascular risk factors in polycystic ovary syndrome / Evanthia Diamanti-Kandarakis -- 33. Insulin resistance and early pregnancy loss in polycystic ovary syndrome / Daniela Jakubowicz and Susmeeta T. Sharma.
  • 2013 Springer
    Mark W. J. Strachan, Brian M. Frier.
    Diabetes is extremely common, with approximately 171 million people affected worldwide. The majority of people with diabetes are cared for in primary care. Primary health care professionals are usually adept at dealing with the lifestyle measures and tablet treatments for diabetes, but generally have limited expertise in the initiation and management of insulin therapy. Insulin therapy has also become more complex, with numerous different forms of insulin and more complex delivery devices available. In a secondary care setting, approximately 10% of in-patients will have diabetes at any one time. People with diabetes stay in hospital longer than people without diabetes, and the condition is often poorly managed during in-patient stays, often leading to clinical errors. Insulin Therapy: A Pocket Guide provides clear and concise information about the safe prescribing of insulin both subcutaneously and intravenously. It covers the different types of insulin, the delivery devices, side effects of insulin and, most importantly, guidance on rational dose adjustment.This book is an invaluable guide for general practitioners and primary care nurses with a special interest in diabetes, as well as junior hospital doctors and specialist medical trainees, advanced nurse practitioners and new diabetes nurse specialists.
  • 2012 Springer
    Derek LeRoith, editor.
    Epidemiology of IGF-1 and cancer / Katharina Nimptsch and Eward Giovannucci -- Aging and cancer : the IGF- I connection / Kalina Biernacka, Claire Perks, and Jeff Holly -- Obesity, type 2 diabetes and cancer / Rosalyn D. Ferguson and Derek LeRoith -- IGF system and breast cancer / Marc A. Becker and Douglas Yee -- The role of insulin-like growth factor signaling in prostate cancer development and progression / Bruce Montgomery, James Dean, and Stephen Plymate -- IGF-1 cellular action and its relationship to cancer : evidence from in vitro and in vivo studies / Rosalyn D. Ferguson ... [et al.] -- Insulin-like growth factor signaling in pediatric sarcomas / Xiaolin Wan, Su Young Kim, and Lee J. Helman -- Cancer genes, tumor suppressors, and regulation of IGF1-R gene expression in cancer / Haim Werner ... [et al.] -- Mouse models of IGF-1R and cancer / Craig I. Campbell, James J. Petrik, and Roger A. Moorehead -- Targeting the insulin-like growth factor-I receptor in cancer therapy / David R. Clemmons -- Targeting insulin-like growth factor receptor 1 (IGF-1R) and insulin receptor signaling by tyrosine kinase inhibitors in cancer / Joan M. Carboni, Mark Wittman, and Fei Huang -- Calories and cancer : the role of insulin-like growth factor-1 / Stephen D. Hursting ... [et al.] -- Cancer cell metabolism / Akash Patnaik, Jason W. Locasale, and Lewis C. Cantley -- Overlaps between the insulin and IGF-I receptor and cancer / Antonino Belfiore and Roberta Malaguarnera.
  • 2013 Springer
    Mary R. Talen, Aimee Burke Valeras, editors.
    Part I: Essentials of Integrated Behavioral Health Care -- Introduction and Overview of Integrated Behavioral Health in Primary Care -- Integrated Behavioral Health and Primary Care: A Common Language -- Integrated Behavioral Health and the Patient-Centered Medical Home -- Advancing Integrated Behavioral Health and Primary Care: The Critical Importance of Behavioral Health in Health Care Policy -- Part II: Review of Integrated Systems of Care Initiatives -- The State of the Evidence for Integrated Behavioral Health in Primary Care -- Community-Based Participatory Research: Advancing Integrated Behavioral Health Care Through Novel Partnerships -- Integrated Behavioral Health in Public Health Care Contexts: Community Health and Mental Health Safety Net Systems -- The Financial History and Near Future of Integrated Behavioral Health Care -- Department of Defense Integrated Behavioral Health in the Patient-Centered Medical Home -- Part III: Review of Collaborative Behavioral Health Clinical Services -- Collaborative Partnerships Within Integrated Behavioral Health and Primary Care -- Identifi cation of Behavioral Health Needs in Integrated Behavioral and Primary Care Settings -- Screening Measures in Integrated Behavioral Health and Primary Care Settings -- Implementing Clinical Interventions in Integrated Behavioral Health Settings: Best Practices and Essential Elements -- Working with Complexity in Integrated Behavioral Health Settings -- Part IV: Connecting Concepts, Research and Practice -- Integrated Behavioral Health in Primary Care: Summarizing the Lay of the Land, Marking the Best Practices, Identifying Barriers, and Mapping New Territory.
  • 2012 Wiley
    edited by Murugan Ramalingam [and others].
  • 2015 PsychiatryOnline
    edited by Lori E. Raney, M.D.
    Evidence base and core principles / Jürgen Unützer, Anna Ratzliff -- Collaborative care team in action / Lori Raney, Gina Lasky, Clare Scott -- Role of the consulting psychiatrist / Lori Raney -- Child and adolescent psychiatry in integrated settings / Barry Sarvet, Robert Hilt -- Risk management liability issues in integrated care / Kristin Lambert, Anton Bland -- Training psychiatrists for integrated care / Anna Ratzliff, Jürgen Unützer, Marcella Pascually -- The case for primary care in public mental health settings / Martha Ward, Benjamin Druss -- Providing primary care in behavioral health settings / John Kern -- Behavioral health homes / Joe Parks -- Management of leading risk factors for cardiovascular disease / Erik Vanderlip, Lydia Chwastiak.
  • 2014 Springer
    Paul Summergrad, Roger G. Kathol, editors.
    Integrated Care in Psychiatry: Redefining the Role of Mental Health Professionals in the Medical Setting is a landmark title in the field, offering a clear, detailed, and cohesive call by leading experts for coordinated care for patients with concurrent psychiatric and medical conditions. The renowned editors and authors argue that what is slowly occurring, and greatly needed at a faster pace, is nothing less than a sea change in the way that psychiatric care will be delivered. The current, mostly segregated, medical and psychiatric model of care has led to the development of competing medical and psychiatric subcultures that have resulted in a lack of dialog among health providers, administrators, and payers -- and thus in less than optimal patient outcomes. To remedy this problem, the book offers a practical, insightful road map to achieving the central tenet of health reform truly coordinated, patient-centered care where the care experience for the patient, the medical care itself, and the cost outcomes improve as the system changes from fee-for-service to population-based health. An invaluable reference for all clinicians, policy makers, payers, administrators, and others interested in the debate surrounding healthcare systems, Integrated Care in Psychiatry: Redefining the Role of Mental Health Professionals in the Medical Setting is a major contribution to the literature and a gold standard resource.
  • 2012 Wiley
    edited by Vinod Krishnan, Ze'ev Davidovitch.
    The increased stature of orthodontics / Ze'ev Davidovitch, Vinod Krishnan -- Effective data management and communication for the contemporary orthodontist / Ameet V Revankar -- Orthodontic diagnosis and treatment planning: collaborating with medical and other dental specialists / Om P Kharbanda, Neeraj Wadhawan -- Psychosocial factors in motivation, treatment, compliance, and satisfaction with orthodontic care / Donald B Giddon, Nina K Anderson -- Nutrition in orthodontic practice / Lauren Schindler, Carole A Palmer -- Anomalies in growth and development: the importance of consultation with a pediatrician / Adriana Da Silveira -- The benefits of obtaining the opinion of a clinical geneticist regarding orthodontic patients / James K Hartsfield Jr -- Multidisciplinary team management of congenital orofacial deformities / Sherry Peter, Maria J Kuriakose -- Cleft lip and palate: role of the orthodontist in the interdisciplinary management team / Anne Marie Kuijpers-Jagtman -- What can orthodontists learn from orthopaedists engaged in basic research? / Carlalberta Verna, Birte Melsen -- When should an orthodontist seek the advice of an endocrinologist? Nadine G Haddad, Linda A DiMeglio -- The benefits of consulting with an ear, nose, and throat (ENT) specialist before and during orthodontic treatment Joseph G Ghafari, Anthony T Macari -- Obstructive sleep apnea: orthodontic strategies to establish and maintain a patent airway / Mimi Yow, Eric Lye Kok Weng -- Acute and chronic infections affecting the oral cavity: orthodontic implications / Vinod Krishnan, Gunnar Dahlén, Ze'ev Davidovitch -- Orthodontics and pediatric dentistry: two specialties, one goal / Elliott M Moskowitz, George J Cisneros, Mark S Hochberg -- Dental caries, tooth fracture and exposed dental pulp: the role of endodontics in orthodontic treatment planning and mechanotherapy / Neslihan Arhun, Ayca Arman-Ozcirpici, Mete Ungor, Omur Polat Ozsoy -- Pre-prosthetic orthodontic tooth movement: interdisciplinary concepts for optimizing prosthodontic care / Julie Holloway, Meade C Van Putten Jr, Sarandeep Huja -- Orthodontic treatment in patients requiring orthognathic surgical procedures / David R Musich -- The role of biomedical engineers in the design and manufacture of customized orthodontic appliances / William A Brantley, Theodore Eliades -- Tissue engineering in orthodontics therapy / Nina Kaukua, Kaj Fried, Jeremy J Mao -- Corticotomy and stem cell therapy for orthodontists and periodontists: rationale, hypotheses, and protocol / Neal C Murphy, Nabil F Bissada, Ze'ev Davidovitch, Simone Kucska -- The application of lasers in orthodontics / Neal D Kravitz -- Implant orthodontics: an interactive approach to skeletal anchorage / Hyo-Sang Park -- Temporomandibular dysfunction: controversies and orthodontics / Donald J Rinchuse, Sanjivan Kandasamy -- Orthodontic treatment for the special needs child / Stella Chaushu, Joseph Shapira, Adrian Becker.
  • 2008 Springer
    Michael Torzewski, Karl J. Lackner, Jürgen Bohl, Clemens Sommer.
  • 2010
    Jonathan S. Daniels.
    Affinity biosensors are important tools for detecting DNA, proteins, cells, and other biomedical analytes. Although optical readout is prevalent, impedance readout is promising for many applications due to lower cost, reduced system size, and label-free operation. Impedance biosensors detect the binding of a target biomolecule to an immobilized probe by quantifying changes in the the electrode-electrolyte interface impedance. Impedance biosensors traditionally use bulky and expensive instruments to monitor the impedance of a single electrode. We describe miniaturized and inexpensive readout circuitry for an array of such sensors. By using a sensor array, multiple analytes can be simultaneously detected and limitations inherent to individual sensors can be mitigated. Reducing the size and cost of the measurement system enables new applications. We present a measurement system for a 6x6 array of impedance biosensors built from off-the-shelf components. Experimental results with DNA probe-target pairs confirm others' reports that changes in the interface impedance can signify binding. Other experiments with proteins demonstrate that changes in the nonlinearity of the I-V relationship can also indicate probe-target binding. We show that the impedance and the nonlinearity can be quantified simultaneously by superimposing a large-amplitude tone on the impedance-measurement tone and analyzing the resulting intermodulation tones. We conclude by describing an integrated array of measurement circuits implemented in 0.18 um CMOS. Each of the 36 measurement pixels contains an impedance-measuring circuit plus tone cancellation circuitry, which enables simultaneous nonlinearity measurement. To prevent the large-amplitude excitation from saturating the amplifier output, a per-pixel digital feedback loop injects an appropriate cancelling current at the amplifier input. Impedance changes of 0.2% can be detected using the integrated measurement circuit. Each pixel occupies 0.14 mm2 and consumes 1.9 mW.
  • 2013 Springer
    Stephen J. Bourke, E. Timothy Peel, editors.
    This book brings together the knowledge, skills and attitudes of specialists in both Respiratory Medicine and Palliative Medicine to focus on the palliative care of patients with respiratory diseases. It deals not only with end-of-life care but also with symptom control and supportive care to improve the quality of life of those living their lives with advanced progressive lung disease.
  • 2009 Springer
    [edited by] Assad Movahed, Gopinath Gnanasegaran, John R. Buscombe, Margaret Hall.
  • 2006
    Michael Schmalz.
    Status: Not Checked OutLane Catalog Record
    Introduction to Access/Excel integration -- Using the Excel user interface -- Data access from Excel VBA -- Integration from the access interface -- Using access VBA to automate Excel -- Using Excel charts and pivot tables with access data -- Leveraging SQL server data with Microsoft Office -- Advanced Excel reporting techniques -- Using Access and Excel data in other applications -- Creating form functionality in Excel -- Building graphical user interfaces -- Tackling an integration project.
  • 2013 Springer
    Pascal Belin, Salvatore Campanella, Thomas Ethofer, editors.
    This book follows a successful symposium organized in June 2009 at the Human Brain Mapping conference. The topic is at the crossroads of two domains of increasing importance and appeal in the neuroimaging/neuroscience community: multi-modal integration, and social neuroscience. Most of our social interactions involve combining information from both the face and voice of other persons: speech information, but also crucial nonverbal information on the person's identity and affective state. The cerebral bases of the multimodal integration of speech have been intensively investigated; by contrast only few studies have focused on nonverbal aspects of face-voice integration. This work highlights recent advances in investigations of the behavioral and cerebral bases of face-voice multimodal integration in the context of person perception, focusing on the integration of affective and identity information. Several research domains are brought together. Behavioral and neuroimaging work in normal adult humans included are presented alongside evidence from other domains to provide complementary perspectives: studies in human children for a developmental perspective, studies in non-human primates for an evolutionary perspective, and studies in human clinical populations for a clinical perspective.
  • 2008 WHO
    PART 1: Primary care for mental health in context -- Chapter 1. Primary care for mental health within a pyramid of health care -- Chapter 2. Seven good reasons for integrating mental health into primary care -- -- PART 2: Primary care for mental health in practice -- Introduction -- Argentina: Physician-led primary care for mental health in Neuquén province, Patagonia region -- Australia: Integrated mental health care for older people in general practices of inner-city Sydney -- Brazil: Integrated primary care for mental health in the city of Sobral -- Chile: Integrated primary care for mental health in the Macul district of Santiago -- India: Integrated primary care for mental health in the Thiruvananthapuram District, Kerala State -- Islamic Republic of Iran: Nationwide integration of mental health into primary care -- Saudi Arabia: Integrated primary care for mental health in the Eastern Province -- South Africa: Integrated primary care services and a partnership for mental health primary care -- Ehlanzeni District, Mpumalanga Province, and Moorreesburg District, Western Cape Province -- Uganda: Integrated primary care for mental health in the Sembabule District -- United Kingdom of Great Britain and Northern Ireland: Primary care for mental health for disadvantaged communities in London -- -- Report conclusions -- -- Annex 1: Improving the practice of primary care for mental health
    Also available: Print – 2008
  • 2009
    Elizabeth Anne Race.
    Status: Not Checked OutLane Catalog Record
  • 2007 CRCnetBASE
    edited by Mary J. Marian, Pamela Williams-Mullen, Jennifer Muir Bowers.
    Fundamentals of integrative nutrition / Cynthia A. Thomson and Robert Lutz -- Ayurveda: the mother of traditional medicine / Mari Clements -- Pregnancy and lactation / Amy A. Drescher, Deborah Pesicka, and Judith Shabert -- Infant and child health / Lisbeth Benoit -- Adolescence / Mary Marian, Richard Wahl, and John D. Mark -- Women's health / Pamela Echeverria and Jyotsna Sahni -- Men's health / Aaron W. Crawford -- Skeletal system and joint health / Lisa High ... [et al.] -- Cardiovascular disease / Ellen Augur and Mary Atkinson -- Nervous system / Ame Golaszewski and Leo McCluskey -- Upper gastrointestinal system / Andrea Avery and Pamela Williams -- Promoting small and large bowel health / Susan Roberts and Mary Krystofiak Russell -- Liver disease / Roschelle Heuberger -- Nutrition and the pancreas / M. Patricia Fuhrman ... [et al.] -- Immune system / Ellyn Silverman ... [et al.] -- Renal nutrition / Margaret Furtado and Carlos DaSilva -- Respiratory health / Jennifer Doley, Richard Berry, and Mary Marian -- Ear health / Duke Johnson -- Skin health / Jennifer Doley and Joseph Genebriera. Fundamentals of integrative nutrition / Cynthia Thomson and Robert Lutz -- Ayurveda: the mother of traditional medicine / Mary Clements -- Pregnancy and lactation / Amy Drescher and Judith Shabert -- Infancy & childhood / Lisbeth Benoit and Pamela Williams -- Adolescence / Mary Marian, Richard Wahl, and John D. Mark -- Women's health / Pam Echeverria and Jotysna Sani -- Men's health / Aaron Crawford -- Skeletal & joint health / Lisa High ... [et al.] -- Cardiovascular health / Ellen Augur and Mary Atkinson -- Nervous system / Ame Golaszewski and Leo McCluskey -- Upper gastrointestinal health / Andrea Avery and Pamela Williams -- Diseases of the small and large bowel / Susan Roberts and Mary Russell -- Liver health / Roschelle Heuberger -- Nutrition and the pancreas / M. Patricia Fuhrman ... [et al.] -- The immune system / Ellyn Silverman ... [et al.] -- Renal health / Margaret Furtado and Carlos DaSilva -- Respiratory health / Richard Berry -- Ear health / Duke Johnson -- Skin health / Jennifer Doley and Joseph Genebriera.
  • 2008 Springer
    Marc J. Poulin, Richard J.A. Wilson, editors.
    Also available: Print – 2008
  • v. 1-3, 1952-.
    French, Thomas Morton.
    Status: Not Checked OutLane Catalog Record
    v. 1. Basic postulates -- v. 2. Integrative process in dreams -- 3. The Reintegrative process in a psychoanalytic treatment.
  • 2011
    David P. Chen.
    Secondary use of electronic health record (EHR) data has the potential to unlock novel insight into human pathophysiology. While EHR data has often been used in retrospective studies, management of public health, and to improve patient safety, its use in discovering underlying molecular mechanisms of human disease and pathophysiology has been limited. Much of this can be attributed to the differing priorities between healthcare providers and basic biological researchers. The advent of biobanks that collect physiological measurements as well as tissue samples and molecular measurements promises to address this issue. However, the sheer number of different biological and clinical measurement modalities hinders the generation of a truly complete view of the human organism. The increased adoption of EHRs as well as growing biological data repositories enables researchers to answer biological questions applicable to the human population. The goal is not to treat humans as experimental organisms, but rather to gain as much knowledge as possible from every patient seen. By viewing EHRs as a repository of perturbations and their associated physiological consequences we can begin to design experiments that leverage EHR data to generate hypotheses that can be further evaluated. This thesis aims to describe methods to summarize EHR biomarker data in a systematic way to enable downstream analysis as well as methods for integrating EHR data and disparate biological data. I will describe the creation of the "clinarray" and its application to specific disease populations to differentiate patients by severity and to discover latent physiological factors associated with disease. I will also describe how to aggregate and analyze clinarrays from across the EHR to build models of aging. Finally I will discuss the use of diseases to integrate EHR data with gene expression data from a disparate biological data source to discover genes related to aging and to generate hypotheses for relationships between biomarkers and genes. The integration of readily available clinical and biological data promises to improve our understanding of phenomics without impacting patient care and adding an unnecessary burden to the healthcare system. It is important for biological research to leverage the increased amount of molecular and environmental data stored in EHRs to build a more complete view of the human organism.
  • 2015
    Peter Schafer & Michele Calvo.
    This study reveals the many opportunities and challenges facing harm reduction providers and their healthcare provider partners as they work to improve and expand the integration of harm reduction and healthcare services. Key informant interviews, focus groups, a comprehensive literature review, and an in-depth case study of a successful co-location model of service integration uncovered effective strategies and instructive experiences to guide integration efforts.
  • 2012 Springer
    Valerie Powell ... [et al.], editors.
    Rationale and Need to Articulate Medical and Dental Data / Valerie J.H. Powell, Franklin M. Din -- HIT Considerations: Informatics and Technology Needs and Considerations / Miguel Humberto Torres-Urquidy -- Metrics and Measurements / Valerie J.H. Powell, Amit Acharya -- Broader Considerations of Medical and Dental Data Integration / Stephen Foreman, Joseph Kilsdonk -- International Perspectives / Miguel Humberto Torres-Urquidy -- An Integrated Medical-Dental Electronic Health Record Environment: A Marshfield Experience / Amit Acharya, Natalie Yoder, Greg Nycz -- Conclusion and Recommendations / Franklin M. Din, Valerie J.H. Powell.
  • 2012 Cambridge
    editors, C.J. Bettinger, J. Rogers, M. Irimia-Vladu, L. Torsi.
    Progress towards Melanin Integration in Bio-Inspired Devices. -- Bio Organic-Based Gate Dielectric Materials for Thin Film Transistors.
  • 2011
    Alan Edward Rorie.
    The work presented in this dissertation primarily focuses on decision-related activity in the lateral intraparietal area (LIP) and, secondarily, the dorsolateral prefrontal cortex (DLPFC). In Chapter 1 we review the previous independent investigations indicating that these areas are separately modulated by sensory information, value information and choice appropriate to represent decisions. We argue that when both sensory and value information must be simultaneously integrated to make choices, it is unknown, if, how and when these areas integrate these factors. We present a behavioral paradigm in which animal subjects must combine sensory and value information, on a trial-to-trial basis, to make optimal choices. This paradigm is based on a well-known motion discrimination task; however, in our task the magnitude of the reward associated with each option varies from trial to trial. On some trials both options are worth equally large or small rewards. On other trials one option's reward is greater than that of the other. In Chapter 2, we demonstrate that in the unequal reward conditions subjects' choices are consistently biased towards the greater magnitude option. Additionally, we will show that this bias is independent of the motion stimulus strength and its magnitude is nearly optimal. In Chapter 3, we observe that single neurons in cortical area LIP consistently, simultaneously and dynamically represent both sensory and value information. We will argue that this representation supports an integrator model of decision making, in which sensory information is accumulated until the decision is resolved by a threshold crossing. Our results support an interpretation of this model in which value information adjusts the likelihood of a threshold crossing by iv raising or lowering the accumulator's initial state. In Chapter 4, we present a preliminary comparison between LIP and DLPFC activity, under identical conditions, suggesting they play fundamentally different roles in decision making. In Chapter 5, we discuss future lines of research.
  • 2005 Springer
    edited by Gary G. Meadows.
    Microenvironmental effects on tumour progression and metastasis -- Role of microenvironment on gene expression, angiogenesis and microvascular function in tumors -- Imaging of angiogenesis in vivo with fluorescent proteins -- The epigenetic influence of the tumor microenvironment on melanoma plasticity -- Dynamics of cell adhesion interactions during melanoma development -- Matrix metalloproteinases: mediators of tumour-host cell interactions -- Role of brain microenvironments in brain metastases -- Influence of the bone microenvironment on breast cancer metastasis to bone -- Interaction of tumour with host stroma in hepatocellular carcinoma -- Dynamic nature of tumour-host interactions within the tumor microenvironment -- Breast cancer progression: a "vicious cycle" of pro-malignancy activities is mediated by inflammatory cells, chemokines and cytokines -- Tumor and host endothelial cell selective interactions and modulation by microenvironmental chemokines: tumor-endothelial cell cross talk specificity -- The role of chemokine receptors, in particular CXCR4, in lymphoma and carcinoma metastasis -- Energy homeostasis and the tumor/host interaction: the role of the brain -- Anti-angiogenic and pro-apoptotic effects of dietary restriction in experimental brain cancer: role of glucose and ketone bodies -- Dietary restriction of specific amino acids modulates tumor and host interactions -- Role of tumour microenvironment in chemoresistance -- Integrin-mediated resistance to chemotherapy-induced apoptosis in cancer cells -- Bone metastasis microenvironment participates in the development of androgen ablation refractoriness and chemotherapy resistance of prostate cancer cells residing in the skeleton: clinical implications -- Current and future therapeutic targets of the tumour-host microenvironment -- Bone stromal cells as therapeutic targets in osseous metastasis -- Organtropism of lung cancer metastasis and its molecular targeted therapy -- Maspin: a novel serine protease inhibitor -- Metastasis suppressor genes: a brief review of an expanding field -- Tumor-host interactions at the metastatic site: MKK4, signal transduction and the stress response.
  • 2013 Springer
    Espen E. Spangenburg, editor.
    The purpose of Integrative Biology of Women's Health is to discuss and identify perspective areas from basic science to clinical interventions that are critical to the future of women's health. As of now there are critical knowledge gaps that exist in our understanding of physiological and cellular function in women that make the prediction of responses to specific interventions daunting. From a scientific evolution of understanding, the existence of research focused on women's health is relatively new and thus there has not been enough time for new information to integrate itself into our current scientific thought process. This book seeks to capture and disseminate our current understanding of scientific advancements relevant to women's health and provide the information to a broad audience. The scientific community has made significant advancements in understanding the unique aspects of women's health in multiple different tissues. Within this book leading researchers in three key areas: skeletal-muscle-bone function, metabolic function, and cardiovascular function have contributed chapters to enlighten or encourage new avenues of thought that would benefit women. The reader will be exposed to a wide range of experimental approaches including physiological, biochemical, molecular techniques in an effort to provide a comprehensive discussion about the biology of women's health.-- Source other than Library of Congress.
  • 2009 IOM
    Victoria Maizes, David Rakel, Catherine Niemiec ; commissioned for the IOM Summit on Integrative Medicine and the Health of the Public, February 2009.
    Integrative medicine has emerged as a potential solution to the American health care crisis. It provides care that is patient-centered, healing oriented, emphasizes the therapeutic relationship, and uses therapeutic approaches originating from conventional and alternative medicine. Initially driven by consumer demand, the attention integrative medicine places on understanding whole persons and assisting with lifestyle change is now being recognized as a strategy to address the epidemic of chronic diseases bankrupting our economy. This paper defines integrative medicine and its principles, describes the history of complementary and alternative medicine (CAM) in American health care, and discusses the current state and desired future of integrative medical practice. The importance of patient-centered care, patient empowerment, behavior change, continuity of care, outcomes research, and the challenges to successful integration are discussed. The authors suggest a model for an integrative health care system grounded in team-based care. A primary health partner, who knows the patient well, is able to addresses mind, body and spiritual needs, and coordinates care with the help of a team of practitioners is at the centerpiece. Collectively, the team can meet all the health needs of the particular patient and forms the patient centered medical home. The paper culminates with ten recommendations directed to key actors to facilitate the systemic changes needed for a functional health care delivery system. Recommendations include creating financial incentives aligned with health promotion and prevention. Insurers are requested to consider the total costs of care, the potential cost-effectiveness of lifestyle approaches and CAM modalities, and the value of longer office visits to develop a therapeutic relationship and stimulate behavioral change. Outcomes research to track the effectiveness of integrative models must be funded, as well as feedback and dissemination strategies. Additional competencies for primary health partners, including CAM and conventional medical providers, will need to be developed to foster successful integrative practices. Skills include learning to develop appropriate health care teams that function well in a medical home, developing an understanding of the diverse healing traditions, and enhancing communication skills. For integrative medicine to flourish in the U.S., new providers, new provider models, and a realignment of incentives and a commitment to health promotion and disease management will be required.
  • 2016 Springer
    Mark A. Moyad.
    This book is designed to capture and clinically review the comprehensive database of clinical research articles that support and do not support the utilization of a variety of dietary supplements and other complementary medicines that physicians are exposed to in their daily practice. The growing list of CAM products that could interfere with surgery (anesthesia, bleeding, outcomes...) and/or conventional medicines is very large and is provided in each section of the book. Additionally, the list of dietary supplements that could be utilized to improve quality of life for breast cancer patients is also emphasized. The various sub-specialty groups in breast are adequately represented, which allows for a physician to rapidly and thoroughly investigate their topic of interest regardless of whether the topic is prevention, treatment, or a specific side effect of treatment. The practical nature of this book cannot be overstated. Chapters include a general overview of the CAM agent, whether or not it has data in medicine and oncology, and a list of potential drug interactions and specific clinical scenarios where it can be utilized or discouraged in the specialty. Each chapter also includes a rapid review A to Z table that covers the clinical take home points for each subject reviewed in each chapter.
  • 2009
    [edited by] May Loo.
    Status: Not Checked OutLane Catalog Record
  • 2012 ClinicalKey
    [edited by] David Rakel.
    Pt. 1 Integrative medicine -- Philosophy of integrative medicine -- Creating optimal healing environments -- The healing encounter -- Pt. 2 Integrative approach to disease -- Affective disorders -- Depression -- Anxiety -- Attention deficit hyperactivity disorder -- Autism spectrum disorder -- Insomnia -- Neurology -- Alzheimer disease -- Headache -- Peripheral neuropathy -- Multiple sclerosis -- Parkinson disease -- Infectious disease -- Otitis media -- Chronic sinusitis -- Viral upper respiratory infection -- HIV disease and AIDS -- Herpes simplex virus -- Chronic hepatitis - Urinary tract infection -- Recurrent yeast infections Lyme disease -- Cardiovascular disease -- Hypertension -- Hearat failure -- Coronary artery disease -- Peripheral vascular disease -- Arrhythmias -- Allergy intolerance -- Asthma -- The allergic patient -- Multiple chemical sensitivity syndrome - Metabolic endocrine disorders -- Insulin resistance and the metabolic syndrome -- Type 2 diabetes -- Hypothroidism -- Hormone replacement in men -- Hormone replacement in women -- Polycystic ovarian syndrome -- Osteoporosis -- An integrative approach to obesity -- Dyslipidemias -- Gastroesophageal reflux disease -- Peptic ulcer disease - Cholelithiasis -- Recurring abdominal pain in pediatrics -- Constipation -- Autoimmune disorders --Fibromyalgia -- Chronic fatigue spectrum -- Rheumatoid arthritis --Inflammatory bowel disease -- Obstetrics gynecology -- Postdates pregnancy -- Labor pain management -- Nausea and vomiting in pregnancy -- Premenstrual syndrome -- Dysmenorrhea -- Uterine fibroids (Leiomyomata) -- Vaginal dryness --; Uroloogy -- Benign prostatic hyperplasia -- Urolithiasis -- Chronic prostatitis -- Erectile dysfunction -- Musculoskeletal Disorders -- Osteoarthritis -- Myofascial pain syndrome -- Chronic low back pain -- Neck pain -- Gout -- Carpal tunnel syndrom -- Epicondylitis -- Dermatology --Atopic dermatitis -- Psoriasis -- Urticaria -- Recurrent aphthous ulceration -- Seborrheic dermatitis -- Acne Vulgaris and acne rosacea -- Human papillomavirus and warts -- Cancer -- Breast cancer -- Lung cancer -- Prostate cancer -- Colorectal cancer -- Skin cancer -- End of life care -- Substance abuse -- Alcoholism and substance abuse -- Ophthalmology -- Cataracts -- Ade related macular degeneration -- Pt. 3 Tools for your practice -- Lifestyle -- Food intolerance and elimination diet -- The glycemic index load -- The antiinflammatory diet -- The DASH diet -- Writing an exercise prescription -- Breathing exercises -- Low back pain exercises -- Mind body -- Self hypnosis techniques -- Relaxatin techniques -- Enhancing heart rate variability -- Guided imagery and interactive guided imagery -- Journaling for health -- Healing through forgiveness -- recommending meditation -- Motivational interviewing -- Emotional awareness for pain -- energy psychology -- Biochemical -- Prescribing probiotics -- Prescribing botanicals -- Detoxification -- Integrative strategies for planetary health -- Biomechanical --; Counterstrain -- Acupuncture for headache -- Acupuncture for nausea and vomiting -- Saline nasal irrigation -- Bioenergetics -- Integrating spiritual assessment and care -- Therapeutic homeopathy -- Human energetic therapies -- Other therapeutic considerations -- Creating a greener clinic: the impact of global warming on health -- Creating ceremony and ritual in the medical encounter -- Appendix: laboratory testing resources in integrative medicine.
  • 2009
    James Lake.
    Status: Not Checked OutLane Catalog Record
    The context of integrative mental health care -- Evaluating a client from an integrative perspective : the intake interview, assessment, and formulation -- Recommending treatment and making referrals -- Moderate and severe depression -- Cyclic mood changes and mania -- Anxiety and panic -- Hyperactivity and distractibility -- Psychotic symptoms and schizophrenia -- Mild cognitive impairment and dementia -- Alcohol and drug abuse -- Insomnia and fatigue.
  • 2012
    Marc A. Schaub.
    Genome Wide Association Studies (GWAS) have identified over 4,500 common variants in the human genome that are statistically associated with diseases and other phenotypical traits. Most identified associations, however, only have a small effect on disease risk, and their relevance in a clinical setting remains the subject of extensive debate. In this thesis I present three integrative analysis directions that extend on GWAS by developing new methods, by using genotyping data to ask new questions, and by integrating additional types of data to generate functional hypotheses about the biological processes underlying associations. First, I introduce a new classifier-based methodology that identifies similarities in the genetic architecture of diseases. This method can successfully identify both known and novel relationships between common diseases. Second, I show how control individuals from a GWAS can be used to detect genetic differences between the pseudoautosomal regions of chromosomes X and Y in the general population. Finally, I present an approach that integrates experimental data generated by the ENCODE consortium in order to identify functional Single Nucleotide Polymorphisms (SNPs). These functional SNPs are associated with a phenotype, either directly or through linkage disequilibrium, and overlap a functional region of the genome such as a transcribed region or a transcription factor binding site. Up to 80% of all associations previously reported in a GWAS can be mapped to a functional SNP.
  • 2010
    Zhengqing Ouyang.
    High-throughput genomics has been increasingly generating the massive amount of genome-wide data. With proper modeling methodologies, we can expect to archive a more comprehensive understanding of the regulatory mechanisms of biological systems. This work presents integrative approaches for the modeling and analysis of gene regulatory systems. In mammals, gene expression regulation is combinatorial in nature, with diverse roles of regulators on target genes. Microarrays (such as Exon Arrays) and RNA-Seq can be used to quantify the whole spectrum of RNA transcripts. ChIP-Seq is being used for the identification of transcription factor (TF) binding sites and histone modification marks. RNA interference (RNAi), coupled with gene expression profiles, allow perturbations of gene regulatory systems. Our approaches extract useful information from those genome-wide measurements for effectively modeling the logic of gene expression regulation. We present a predictive model for the prediction of gene expression from ChIP-Seq signals, based on quantitative modeling of regulator-gene association strength, principal component analysis, and regression-based model selection. We demonstrate the combinatorial regulation of TFs, and their power for explaining genome-wide gene expression variation. We also illustrate the roles of covalent histone modification marks on predicting gene expression and their regulation by TFs. We present a dynamical model of gene expression profiling, and derive the perturbed behaviors of the ordinary differential equation (ODE) system. Based on that, we present a regularized multivariate regression method for inferring the gene regulatory network of a stable cell type. We model the sparsity and stability of the network by a regularization approach. We applied the approaches to both a simulation data set and the RNAi perturbation data in mouse embryonic stem cells.
  • 2008 Springer
    editors, Lorenzo Cohen, Maurie Markman.
    Introduction -- A word of caution: risk of harm associated with alternative complementary/integrative approaches in cancer management and the critical need for quality research to understand and decrease that risk -- Using legal and ethical principles to guide clinical decision making in complementary/integrative cancer medicine -- Communicating with patients about the use of complementary and integrative medicine in cancer care -- The integrative medicine program at The University of Texas M. D. Anderson Cancer Center -- The integrative medicine service at Memorial Sloan-Kettering Cancer Center -- Integrative oncology-Leonard P. Zakim Center: the Dana-Farber Cancer Institute experience -- The Johns Hopkins complementary and integrative medicine service -- Integrative oncology at Mayo Clinic: research informing practice -- Mind-body research in cancer -- Herbs and other botanicals: interactions with pharmaceuticals -- Acupuncture in cancer care at Dana-Farber Cancer Institute: an integrative medical practice -- Acupuncture for the side effects of cancer treatments.
  • 2008 Springer
    edited by Joseph F. Audette, Allison Bailey.
  • 2012 Springer
    Alfred Längler, Patrick J. Mansky, Georg Seifert, editors.
    This practice-oriented handbook covers complementary and alternative medicine (CAM) practices in pediatric oncology worldwide, with a focus on methods used in Western countries. Provides a road map for establishing integrative pediatric oncology worldwide.
  • 2005 Springer
    edited by Wolfgang Walz.
  • 2003 ScienceDirect
    edited by John T. Romeo.
    The enzymatic basis of flavonoid biodiversity / Ragai K. Ibrahim and Dominique Anzellotti -- Structural, functional and evolutionary basis for methylation of plant small molecules / Joseph P. Noel ... [et al.] -- Regulation of anthocyanin pigmentation / Niloufer G. Irani, J. Marcela Hernandez and Erich Grotewold -- Localization of plant myrosinases and glucosinolates / Erik Andreasson and Lise Bolt Jorgensen -- Glucosinolate hydrolysis and its impact on generalist and specialist insect herbivores / Ute Wittstock ... [et al.] -- A novel myrosinase-glucosinolate defense system in cruciferous specialist aphids / John T. Rossiter, Alexnadra M. Jones and Atle M. Bones -- Multiple levels of control in the regulation of alkaloid biosynthesis / Peter J. Facchini ... [et al.] -- Biochemistry and molecular biology of indole alkaloid biosynthesis : the implication of recent discoveries / Vincenzo de Luca -- Chemical ecology of alkaloids exemplified with the pyrrolizidines / Dietrich Ober -- The chemical wizardry of isoprenoid metabolism in plants / Bryan T. Greenhagen ... [et al.] -- The sabath family of MTS in Arabidopsis Thaliana and other plant species / John C. D'Auria, Feng Chen, Eran Pichersky -- Xochipilli updated, terpenes from Mexican plants / Edmundo Lozoya-Gloria.
  • 2006 ScienceDirect
    edited by John T. Romeo.
    Terpene indole alkaloid biosynthesis / Sarah E. O'Connor, Elizabeth McCoy -- Pathways to diverse ergot alkaloid profiles in fungi / Daniel G. Panaccione, Christopher L. Schardl, Christine M. Coyle -- Compartmentalization of plant secondary metabolism / Nailish Samanani, Peter J. Facchini -- Comparative genomics of the shikimate pathways in Arabidopsis, Populus trichocarpa and Oryza sativa : shikimate pathway gene family structure and identification of candidates for missing links in pehnylalanine biosynthesis / Björn Hamberger ... [et al.] -- Tomato glandular trichomes as a model system for exploring evolution of specialized metabolism in a single cell / Eyal Fridman ... [et al.] -- Anacardic acid biosynthesis and bioactivity / David J. Schultz, Nalinie S. Wickramasinghe, Carolyn M. Klinge -- Molecular and biochemical investigations of sorgoleone biosynthesis / Daniel Cook ... [et al.] -- Biosynthesis of terpenophenolic metabolites in hop and cannabis / Jonathan E. Page, Jana Nagel -- Engineering pathway enzymes to understand the function and evolution of sterol structure and activity / Pruthvi Jayasimha ... [et al.] -- Methylation and demethylation of plant signaling molecules / Yue Yang ... [et al.] -- Recent advances in auxin biosynthesis and conjugation / Amber Kei Bowers, Yunde Zhao -- Auxin biology and biosynthesis / Jessica Calio, Yuen Yee Tam, Jennifer Normanly -- Translational opportunities in plant biochemistry / Cecilia A. McIntosh.
  • 2012 Springer
    Linda Chlan, Marshall I. Hertz, editors.
    Overview of integrative therapies and healing practices -- Evaluation of integrative therapies for research and practice -- Integrative therapies in chronic pulmonary conditions -- Integrative therapies for people with asthma -- Integrative therapies for people with asthma -- Integrative therapies for people with chronic obstructive pulmonary disease -- Integrative therapies for people with interstitial lung disease, idiopathic pulmonary fibrosis, and pulmonary arterial hypertension -- Integrative therapies for people with cystic fibrosis -- Integrative therapies for people with lung cancer -- Integrative therapies for lung transplantation recipients -- Integrative therapies in critical care and sleep disorders -- Integrative therapies in the management of critically ill patients -- Integrative therapies to promote sleep in the intensive care unit -- Future application of integrative therapies for sepsis: bench and experimental animal models -- Integrative therapies to manage acute and chronic sleep disorders -- Integrative therapies to promote lung health -- Integrative therapies for tobacco cessation -- Integrative therapies to support palliative and end-of-life care in lung disease -- Whole medical systems in lung health and sleep: focus on traditional Chinese medicine -- Counseling patients with chronic lung disease: interdisciplinary strategies for reducing distress.
  • 2014 CRCnetBASE
    Joel A. Blush, M.D., Ph.D.
    "This book provides practical hands-on advice on the use of alternative methods of hypertension treatment. It describes mechanisms of high blood pressure and hypertension, common causes of hypertension, and standard medications used to treat the disease and their side effects. The book details alternative methods of treating hypertension, emphasizing their mechanisms of action, similarities to standard medications, and practical implementation advice. Finally, it outlines guidelines for blood pressure goals, categorizes each treatment as medicine or alternative, and suggests ways of implementing an integrative approach to hypertension treatment"--Provided by publisher.
  • 2014 Springer
    Gerard E. Mullin, Lawrence J. Cheskin, Laura E. Matarese, editors.
    Integrative Weight Management: A Guide for Clinicians intends to educate physicians and nutritionists about the wide ranges of approaches to weight control from non-traditional sources. The options for weight management in conventional practices are limited to a small number of medications, a confusing array of dietary approaches and surgical procedures with their inherent risks and complications. Unfortunately medical practitioners are not exposed to nutrition and weight control principles during training and thus are reluctant to manage their patients weight control issues. This volume is structured into 4 sections: Introduction to Weight Management Disorders; Morbidity and Mortality of Obesity; Therapy of Obesity; and Integrative Medicine and Obesity. Integrative Weight Management: A Guide for Clinicians represents a powerful collaboration of dozens of leading experts in the fields of nutrition, weight management and integrative medicine who have managed countless numbers of patients and summarized the research from thousands of articles to create an up-to- date state of the art guide for healthcare practitioners, allied health professionals and public health authorities who manage those who are overweight/obese along with the associated metabolic consequences.
  • 2011 Springer Protocols
    edited by Motomu Shimaoka.
    Overview : assays for studying integrin-dependent cell adhesion / Alexandre Chigaev and Larry A. Sklar -- Cell adhesion assays / Gabriele Weitz-Schmidt and Stephanie Chreng -- Real-time analysis of integrin-dependent transendothelial migration and integrin-independent interstitial motility of leukocytes / Ziv Shulman and Ronen Alon -- Lentiviral gene transfer method to study integrin function in T lymphocytes / Daliya Banerjee and Motomu Shimaoka -- Surface plasmon resonance biosensing in studies of the binding between b2 integrin I domains and their ligands / Thomas Vorup-Jensen -- Cell-free ligand-binding assays for integrin LFA-1 / Koichi Yuki -- Overview : structural biology of integrins / Guanyuan Fu, Wei Wang, and Bing-Hao Luo -- Protein expression and purification of integrin I domains and IgSF ligands for crystallography / Hongmin Zhang and Jia-huai Wang -- Electron microscopic imaging of integrin / Kenji Iwasaki -- NMR method to study protein-protein interactions / Noritaka Nishida and Ichio Shimada -- Single-molecule methods to study cell adhesion molecules / Joonil Seog -- Overview : imaging in the study of integrins / Christopher V. Carman -- Live imaging of LFA-1-dependent T-cell motility and stop signals / Andrew J. Wiemer, Sarah Wernimont, and Anna Huttenlocher -- Monitoring integrin activation by fluorescence resonance energy transfer / Craig T. Lefort, Young-Min Hyun, and Minsoo Kim -- High-resolution fluorescence microscopy to study transendothelial migration / Christopher V. Carman -- Multiphoton intravital microscopy to study lymphocyte motility in lymph nodes / Thomas T. Murooka and Thorsten R. Mempel -- Overview of integrin signaling in the immune system / Tatsuo Kinashi -- Rap1 and integrin inside-out signaling / Koko Katagiri and Tatsuo Kinashi -- Isolation of focal adhesion proteins for biochemical and proteomic analysis / Jean-Cheng Kuo [and others] -- Talin and signaling through integrins / Mohamed Bouaouina, David S. Harburger, and David A. Calderwood -- Proteomics method for identification of pseudopodium phosphotyrosine proteins / Yingchun Wang and Richard L. Klemke -- Overview : studying integrins in vivo / Clifford A. Lowell and Tanya N. Mayadas -- Method for the generation of conditional gene-targeted mice / Masahiro Yamamoto and Kiyoshi Takeda -- T-cell homing to the gut mucosa : general concepts and methodological considerations / Jaime De Calisto [and others] -- In vivo quantitative proteomics : the SILAC mouse / Sara Zanivan, Marcus Krueger, and Matthias Mann -- Analysis of chemotaxis in Dictyostelium / Huaqing Cai [and others] -- Integrins in tumor angiogenesis and lymphangiogenesis / Philippe Foubert and Judith A. Varner -- PET-radioimmunodetection of integrins : imaging acute colitis using a 6464Cu-labeled anti-B7 integrin antibody / Jason L.J. Dearling and Alan B. Packard -- Integrin-targeted nanoparticles for siRNA delivery / Noa Ben-Arie, Ranit Kedmi, and Dan Peer -- Humanized mice for studying human leukocyte integrins in vivo / Sang-Soo Kim [and others].
  • 2007 ScienceDirect
    edited by David A. Cheresh.
    Also available: Print – 2007
  • 2010 Springer
    edited by Andrea Becchetti, Annarosa Arcangeli.
    Integrin structure and functional relation with ion channels / Annarosa Arcangeli and Andrea Becchetti -- Introduction to ion channels / Chiara Di Resta and Andrea Becchetti -- Biochemical methods to study the interactions between integrins and ion channels / Olivia Crociani -- Optical methods in the study of protein : protein interactions / Alessio Masi ... [et al.] -- Integrins and signal transduction / -- Sara Cabodi ... [et al.] -- Physical and functional interaction between integrins and herg1 channels in cancer cells / Serena Pillozzi and Annarosa Arcangeli -- Coordinated regulation of vascular Ca2+ and K+ channels by integrin signaling / Peichun Gui ... [et al.] -- Adhesion : dependent modulation of macrophage K+ channels / Margaret Colden-Stanfield -- Integrin receptors and ligand : gated channels / Raffaella Morini and Andrea Becchetti -- Integrins and ion channels in cell migration : implications for neuronal development, wound healing and metastatic spread / Andrea Becchetti and Annarosa Arcangeli.
    Also available: Print – 2010
  • 2014 Springer
    Joanna T. Brougher.
    Introduction to intellectual property -- Obtaining, enforcing and defending patents -- The patent-eligibility of genes -- Medical procedure patents -- Rights and roles of universities and inventors -- Drug development : balancing innovation, access and profits -- Patent battles part I : small-molecule drugs -- Patent battles part II : the Biosimilars Act and biologics -- International patent law, trade law, and access to drugs.
  • 2004 Wiley
    Howard B. Rockman.
    ch. 1. Overview of Intellectual Property Law, p. 1-8 -- ch. 2. The Use of Intellectual Property in Business, p. 9-29 -- ch. 3. How to Read and Obtain Information from a Modern U.S. Patent, p. 31-45 -- ch. 4. Introduction to Patents, p. 47-67 -- ch. 5. Patentable Subject Matter and Utility, p. 69-74 -- ch. 6. Novelty: The Invention Must Be New, p. 75-86 -- ch. 7. Requirement of Non-Obviousness for Patentability, p. 87-101 -- ch. 8. The Patenting Process, p. 103-128 -- ch. 9. Novelty, Infringement, and Other Searches, p. 129-140 -- ch. 10. Patent Application, p. 141-154 -- ch. 11. Claims of a Patent Application, p. 155-170 -- ch. 12. Prosecution of a Patent Application, p. 171-191 -- ch. 13. Design Patents, p. 193-210 -- ch. 14. Protection of Computer-Related Inventions, p. 211-253 -- ch. 15. Patentability of Biotechnology Inventions, p. 255-271 -- ch. 16. Business Method Protection, p. 273-286 -- ch. 17. Foreign Patent Protection, p. 287-300 -- ch. 18. Enforcement of the Patent Right, p. 301-316 -- ch. 19. Ownership and Transfer of Patent Rights, p. 317-336 -- ch. 20. Employment Contracts and Non-Compete Restrictions, p. 337-368 -- ch. 21. The Engineer and Scientist as Expert Witness; and Ethics, p. 369-381 -- ch. 22. Copyrights as a Vehicle for Technology Protection, p. 383-403 -- ch. 23. The Digital Millennium Copyright Act of 1998 (DMCA): An Overview, p. 405-418 -- ch. 24. Mask Work Protection, p. 419-428 -- ch. 25. Trade Secrets, p. 429-441 -- ch. 26. Trademarks, p. 443-456 -- ch. 27. Cybersquatting, p. 457-465 -- ch. 28. Current Events, p. 467-473.
  • 2008 CRCnetBASE
    edited by Olivier C.L. Haas, Keith J. Burnham.
  • 2013 ScienceDirect
    Syed V. Ahamed.
    This textbook offers an insightful study of the intelligent Internet-driven revolutionary and fundamental forces at work in society. Readers will have access to tools and techniques to mentor and monitor these forces rather than be driven by changes in Internet technology and flow of money. These submerged social and human forces form a powerful synergistic foursome web of (a) processor technology, (b) evolving wireless networks of the next generation, (c) the intelligent Internet, and (d) the motivation that drives individuals and corporations. In unison, the technological forces can tear human lives apart for the passive or provide a cohesive set of opportunities for the knowledgeable to lead and reap the rewards in the evolved knowledge society. The book also provides in-depth coverage of the functions embedded in modern processors and intelligent communication networks. It focuses on the convergence of the design of modern processor technologies with the switching and routing methodologies of global intelligent networks. Most of the concepts that are generic to the design of terra-flop parallel processors and the terra-bit fiber-optic networks are presented. This book also highlights recent developments in computer and processor technologies into the microscopic and macroscopic medical functions in hospitals and medical centers. Examination of the latest technologies and innovations presented from academic and industrial perspectives of the concurrent dynamic changes in computer and communication industries. An up-to-date and coherent perspective of the developments in the wireless and fiber optic network technologies based on the experience and developments in the older copper, cable and hybrid fiber-coaxial communication systems. Provides a set of novel concepts and methodologies for the innovators in industry -- Source other than Library of Congress.
  • 2005 Springer
    Barry G. Silverman ... [et al.].
    Computerization of clinical guidelines : an application of medical document processing / Gersende Georg -- Case-based medical informatics / Stefan V. Pantazi, José F. Arocha and Jochen R. Moehr -- Analysis and architecture of clinical workflow systems using agent-oriented lifecycle models / James P. Davis and Raphael Blanco -- Virtual communities in health care / George Demiris -- Evidence based telemedicine / George Anogianakis ... [et al.] -- Current status of computerized decision support systems in mammography / G.D. Tourassi -- Medical diagnosis and prognosis based on the DNA microarray technology / Y. Fukuoka, H. Inaoka and I.S. Kohane -- Wearable devices in healthcare / Constantine Glaros and Dimitrios I. Fotiadis.
  • 2012 Wiley
    edited by Marcus Textor, H. Michelle Grandin.
    Frontmatter -- Color Plates -- Stimulus-Responsive Polymers as Intelligent Coatings for Biosensors: Architectures, Response Mechanisms, and Applications / Vinalia Tjong, Jianming Zhang, Ashutosh Chilkoti, Stefan Zauscher -- Smart Surfaces for Point-of-Care Diagnostics / Michael A Nash, Allison L Golden, John M Hoffman, James J Lai, Patrick S Stayton -- Design of Intelligent Surface Modifications and Optimal Liquid Handling for Nanoscale Bioanalytical Sensors / Laurent Feuz, Fredrik H̲̲k, Erik Reimhult -- Intelligent Surfaces for Field-Effect Transistor-Based Nanobiosensing / Akira Matsumoto, Yuji Miyahara, Kazunori Kataoka -- Supported Lipid Bilayers: Intelligent Surfaces for Ion Channel Recordings / Andreas Janshoff, Claudia Steinem -- Antimicrobial and Anti-Inflammatory Intelligent Surfaces / Hans J Griesser, Heike Hall, Toby A Jenkins, Stefani S Griesser, Krasimir Vasilev -- Intelligent Polymer Thin Films and Coatings for Drug Delivery / Alexander N Zelikin, Brigitte St̃dler -- Micro- and Nanopatterning of Active Biomolecules and Cells / Daniel Aydin, Vera C Hirschfeld-Warneken, Ilia Louban, Joachim P Spatz -- Responsive Polymer Coatings for Smart Applications in Chromatography, Drug Delivery Systems, and Cell Sheet Engineering / Roǧrio P Pirraco, Masayuki Yamato, Yoshikatsu Akiyama, Kenichi Nagase, Masamichi Nakayama, Alexandra P Marques, Rui L Reis, Teruo Okano -- Index.
  • 2003 ScienceDirect
    edited by Bernadette Bouchon-Meunier, Laurent Foulloy, Ronald R. Yager.
  • 2015 Springer
    Yasumasa Nishimura, Ritsuko Komaki, editors.
    Successful clinical use of intensity-modulated radiation therapy (IMRT) represents a significant advance in radiation oncology. Because IMRT can deliver high-dose radiation to a target with a reduced dose to the surrounding organs, it can improve the local control rate and reduce toxicities associated with radiation therapy. Since IMRT began being used in the mid-1990s, a large volume of clinical evidence of the advantages of IMRT has been collected. However, treatment planning and quality assurance (QA) of IMRT are complicated and difficult for the clinician and the medical physicist. This book, by authors renowned for their expertise in their fields, provides cumulative clinical evidence and appropriate techniques for IMRT for the clinician and the physicist. Part I deals with the foundations and techniques, history, principles, QA, treatment planning, radiobiology and related aspects of IMRT. Part II covers clinical applications with several case studies, describing contouring and dose distribution with clinical results along with descriptions of indications and a review of clinical evidence for each tumor site. The information presented in this book serves as a valuable resource for the practicing clinician and physicist.
  • 2005 Springer
    A. Gullo, P.D. Lumb (eds.).
  • 2009 Springer
    Antonino Gullo, José Besso, Philip D. Lumb, Ged F. Williams, (eds.).
  • 2008 ClinicalKey
    Charles Hinds, David Watson.
    Planning, organization, and management -- Outcome and costs -- Applied cardiovascular and respiratory physiology -- Assessment and monitoring of cardiovascular function -- Shock, sepsis and multiple-organ failure -- Assessment and monitoring of respiratory function -- Respiratory support -- Respiratory failure -- Myocardial ischaemia, cardiopulmonary resuscitation and management of arrhythmias -- Trauma -- General aspects of managing critically ill patients -- Infection in the critically ill -- Acute renal failure -- Acute liver failure -- Neurological disorders -- Gastrointestinal disorders -- Endocrine emergencies -- Obstetric intensive care -- Poisoning -- Disturbances of body temperature -- Transporting the critically iii.
    Also available: Print – 2008
  • 2005-2010. Springer
  • 2008 Springer
    editor, Jean-Louis Vincent.
  • 2006 Springer
    M.P. Fink, P.M. Suter, W.J. Sibbald (eds.).
    Also available: Print – 2006
  • 2014 ClinicalKey
    [edited by] Paul N. Lanken, Scott Manaker, Benjamin A. Kohl, C. William Hanson III.
    Approach to Acute Respiratory Failure -- Approach to Mechanical Ventilation -- Noninvasive Ventilation -- Liberation and Weaning from Mechanical Ventilation and Extubation -- Sedation and Analgesia during Mechanical Ventilation -- Use of Neuromuscular Blocking Agents -- Assessment and Monitoring of Hemodynamic Function -- Cardiogenic Shock and Other Pump Failure States -- Hemorrhagic Shock -- Septic Shock -- Vascular Access Issues and Procedures -- Approach to Supportive Care and Noninvasive Bedside Monitoring -- Management of the Critical Care Patient -- Health Care-Associated Infections -- Nutritional Therapy -- Nutrition-Related Access Procedures -- Pharmacokinetic Alterations in the Critically Ill -- Rational Use of Antimicrobials -- Rational Use of Blood Products -- Renal Replacement Therapy -- Rehabilitation Interventions and Recovery from Critical Illness -- Swallowing and Communication Disorders -- Care of the Patient Infected with Human Immunodeficiency Virus Infection -- Care of the Cancer Patient with Neutropenia or Thrombocytopenia -- Care of the Challenge-to-Wean Patient -- Care of the Patient with End-Stage Renal Disease -- Care of the Patient with End-Stage Liver Disease -- Care of the Maternal-Fetal Unit -- Care of the Patient with Morbid Obesity -- Airways and Emergency Airway Management -- Alcohol Withdrawal: Diagnosis and Management -- Allergies to Antibiotics -- Arrhythmias (Bradycardias) -- Arrhythmias (Tachycardias) -- Barotrauma and Chest Tubes -- Change in Mental Status -- Delirium in the Intensive Care Unit: Diagnosis and Treatment -- Diarrhea Developing in the Intensive Care Unit Patient -- Electrolyte Disorders -- Ileus -- Increased Intracranial Pressure -- Pressure Ulcers: Prevention and Management -- Skin Rashes -- Sleep Disturbances in the Intensive Care Unit -- Thrombocytopenia -- Transfusion Reactions -- Ventilator Alarm Situations -- Weakness Developing in the Intensive Care Unit Patient -- Advanced Cardiac Life Support (ACLS) and Therapeutic Hypothermia -- Chest Pain and Myocardial Ischemia -- Thoracic Aortic Aneurysms and Dissections -- Acute Heart Failure Syndromes -- Hypertensive Crisis and Management of Hypertension -- Pericardial Tamponade -- Hypothermia and Hyperthermia -- Smoke Inhalation and Carbon Monoxide Poisoning -- Drug Overdoses and Toxic Ingestions -- Acute Pancreatitis -- Acute Liver Failure -- Lower Gastrointestinal Bleeding and Colitis -- Upper Gastrointestinal Bleeding -- Hemolytic Anemia -- Idiopathic and Thrombotic Thrombocytopenias -- Acute Central Nervous System Infections -- Community-Acquired Pneumonia -- Necrotizing Fasciitis and Related Soft Tissue Infections -- Acute Neuromuscular Weakness -- Brain Death and Management of Potential Organ Donors -- Neurologic Assessment and Prognosis after Cardiopulmonary Arrest -- Status Epilepticus -- Stroke -- Obstetric and Postobstetric Complications -- Acute Lung Injury and Acute Respiratory Distress Syndrome -- Alternative Modes of Ventilation in Acute Lung Injury -- Acute Respiratory Failure Due to Asthma -- Acute Respiratory Failure Due to Chronic Obstructive Pulmonary Disease -- Deep Venous Thrombosis and Pulmonary Embolism -- Diffuse Alveolar Hemorrhage -- Massive Hemoptysis -- Obesity Hypoventilation Syndrome and Other Sleep-Related Breathing Disorders -- Acute Kidney Injury and Rhabdomyolysis -- Diabetic Ketoacidosis, Hyperglycemic Hyperosmolar State, and Alcoholic Ketoacidosis -- Metabolic Acidoses and Alkaloses -- Disorders of Water Homeostasis: Hyponatremia and Hypernatremia -- Thyroid and Adrenal Disorders in the Intensive Care Unit -- Perioperative Approach to the High-Risk Surgical Patient -- Management of Postoperative and Other Acute Pain -- Cardiac Surgery -- Craniotomy -- Major Abdominal Surgery: Postoperative Considerations -- Major Tissue Flaps -- Major Vascular Procedures -- Perioperative Care of the Morbidly Obese Patient -- Thoracic Surgical Patient -- Approach to the Trauma Patient -- Critical Care for the Orthopedic Patient -- Abdominal Trauma -- Extremity and Major Vascular Trauma -- Head Trauma -- Thoracic Trauma -- Spinal Injury -- Ethical Principles, Communication, and End-of-Life Care -- Teamwork and Collaborative Practice in the Intensive Care Unit -- Family-Centered Care and Communication with Families of Intensive Care Unit Patients -- Providing Culturally Competent Care -- Sleep Deprivation and Sleepiness in Medical Housestaff and Appropriate Countermeasures -- Medical Errors and Patient Safety -- Medical Malpractice, Risk Management, and Chart Documentation -- Long-Term Acute Care in the Spectrum of Critical Care Medicine -- Rapid Response Systems: Rapid Response Teams and Medical Emergency Teams -- Telemedicine Applied to the Intensive Care Unit -- Transporting the Intensive Care Unit Patient.
  • 2016 Springer
    David Crippen, editor.
    This book brings together personal narratives from critical care medicine specialists around the world. Most of these physicians started in critical care at or before the exponential increase in technological modalities to reverse or sustain organ function, have seen patient care both ways, and have worked as many as 30 years or more at the bedside. The narratives are organized around such themes as : how and why these physicians entered the discipline of critical care; what was critical care like in the beginning; how they have experienced the flood of innovations in critical care; why they decided to retire (or not); and what their retirement options have been (or not). Composed by influential critical care medicine specialists, The Intensivist?s Challenge: Aging and Career Growth in a High-Stress Medical Specialty is a valuable resource bringing together a discussion of the nature and problems of aging as they apply to physicians in a high-stress occupation, while assessing the value of clinical experience at the bedside in a world increasingly full of soulless technology.
  • 2007 Springer
    edited by João O. Malva ; co-editors, Ana C. Rego, Rodrigo A. Cunha, and Catarina R. Oliveira.
  • 2014 Springer
    Magdalena Klink, editor.
    The tumor environment is a dynamic network that includes cancer cells, immune cells, fibroblasts, endothelial cells, extracellular matrix, cytokines and receptors. The aim of this book is to summarize the role of these components, especially immune cells, in tumor suppression and/or progression and describe in detail why tumor cells can survive and spread in spite of the antitumor response of immune cells. Since immunotherapy is an attractive approach to cancer therapy, this book also provides information on the two main strategies: monoclonal antibodies and adaptive T cell immunotherapy, with a focus on recent human clinical trials. The book provides a state-of-the-art, comprehensive overview of immune cells in cancer and is an indispensable resource for scientists and medical doctors working and/or lecturing in the field of cancer research and immunology.
  • 2006/2007
    Ashley E. Fouts.
    Status: Not Checked OutLane Catalog Record
  • 2012 Springer
    Gerri S. Hall, editor.
    Antifungal agents -- Antifungal susceptibility testing: Clinical Laboratory and Standards Institute (CLSI) methods -- Antifungal susceptibility testing methods: non-CLSI methods for yeast and moulds -- Susceptibility testing of dermatophytes -- Usual susceptibility patterns of common yeasts -- Usual susceptibility patterns of common moulds and systemic fungi -- Usual susceptibility patterns for systemic dimorphic fungi -- Utility of antifungal susceptibility testing and clinical correlations.
  • 2008
    Curtis M. Rimmerman ; Anil K. Jain.
    Status: Not Checked OutLane Catalog Record
  • 2014 CRCnetBASE
    editor, Enrica Pessione.
    "This book underlines the importance of reciprocal interactions between probiotics and humans in terms of stress induction, epigenetic control of cellular responses, oxidative status, bio-active molecules biosynthesis, moonlighting proteins secretion, endogenous toxins neutralization, and several other biological functions. It explores how these responses can affect metabolism and metabolic-related disorders, gutbrain axis balance, mood, inflammatory, allergic and anti-infective reactions, cancer, and ageing. The book explores how probiotics create a dynamic and "fluid" network of signals able to control the balance between healthy and altered human status"--Provided by publisher.
  • 2011 ClinicalKey
    editors-in-chief, Edward A. Dennis, Ralph A. Bradshaw.
    "Cell signaling, which is also often referred to as signal transduction or, in more specialized cases, transmembrane signaling, is the process by which cells communicate with their environment and respond temporally to external cues that they sense there. All cells have the capacity to achieve this to some degree, albeit with a wide variation in purpose, mechanism, and response. At the same time, there is a remarkable degree of similarity over quite a range of species, particularly in the eukaryotic kingdom, and comparative physiology has been a useful tool in the development of this field. The central importance of this general phenomenon (sensing of external stimuli by cells) has been appreciated for a long time, but it has truly become a dominant part of cell and molecular biology research in the past three decades, in part because a description of the dynamic responses of cells to external stimuli is, in essence, a description of the life process itself. This approach lies at the core of the developing fields of proteomics and metabolomics, and its importance to human and animal health is already plainly evident"--Provided by publisher.
  • 2014 Wiley
    Joseph Noar.
    Introduction : what do we know about growth? -- Recognizing the problem : is a nice smile important? -- Investigations -- Managing the developing occlusion.
  • 2013 Springer
    edited by Ichiro Wakabayashi and Klaus Groschner.
    This book provides an introduction to the principles of both cardiovascular epidemiology and molecular pathophysiology; as a unique aspect, it also outlines and discusses the molecular concepts underlying epidemiological observations. This first volume is focused on the genetic and molecular basis of pathogenesis and the role of environmental factors triggering cardiovascular dysfunctions. The book promotes the use of interdisciplinary approaches in the field of preventive medicine based on recent advances in molecular and cellular pathophysiology. The book offers a valuable resource work for researchers in basic biomedical fields and clinical scientists alike, as well as guidelines for novel avenues of research in both basic pathophysiology and cardiovascular therapy and prevention.
  • 2013 Springer
    Ichiro Wakabayashi, Klaus Groschner, editors.
    This book provides an introduction to the principles of both cardiovascular epidemiology and molecular pathophysiology; as a unique aspect, it also outlines and discusses the molecular concepts underlying epidemiological observations.
  • 2014 Springer
    Ichiro Wakabayashi, Klaus Groschner, editors.
    This book provides an introduction to the principles of both cardiovascular epidemiology and molecular pathophysiology; as a unique aspect, it also outlines and discusses the molecular concepts underlying epidemiological observations. This third volume is focused on the most common cardiovascular events to provide an overview on pathogenesis and clinical aspects. The book promotes the use of interdisciplinary approaches in the field of preventive medicine based on recent advances in molecular and cellular pathophysiology. The book offers a valuable resourcefor researchers in basic biomedical fields and clinical scientists alike, as well as guidelines for novel avenues of research in both basic pathophysiology and cardiovascular therapy and prevention.
  • 2005 Springer
    George Christakos ... [et al.].
    Toward an interdisciplinary methodology -- Stochastic modelling -- Black Death: the background -- Mathematical formulation of the knowledge bases -- Spatiotemporal mapping of the epidemic -- Epea pteroenta.
  • 2011
    Der-Song Lin.
    Capacitive micromachined ultrasonic transducers (CMUTs), have been widely studied in academia and industry over the last decade. CMUTs provide many benefits over traditional piezoelectric transducers including improvement in performance through wide bandwidth, and ease of electronics integration, with the potential to batch fabricate very large 2D arrays with low-cost and high-yield. Though many aspects of CMUT technology have been studied over the years, packaging the CMUT into a fully practical system has not been thoroughly explored. Two important interfaces of packaging that this thesis explores are device encapsulation (the interface between CMUTs and patients) and full electronic integration of large scale 2D arrays (the interface between CMUTs and electronics). In the first part of the work, I investigate the requirements for the CMUT encapsulation. For medical usage, encapsulation is needed to electrically insulate the device, mechanically protect the device, and maintain transducer performance, especially the access of the ultrasound energy. While hermetic sealing can protect many other MEMS devices, CMUTs require mechanical interaction to a fluid, which makes fulfilling the previous criterion very challenging. The proposed solution is to use a viscoelastic material with the glass-transition-temperature lower than room temperature, such as Polydimethylsiloxane (PDMS), to preserve the CMUT static and dynamic performance. Experimental implementation of the encapsulated imaging CMUT arrays shows the device performance was maintained; 95 % of efficiency, 85% of the maximum output pressure, and 91% of the fractional bandwidth (FBW) can be preserved. A viscoelastic finite element model was also developed and shows the performance effects of the coating can be accurately predicted. Four designs, providing acoustic crosstalk suppression, flexible substrate, lens focusing, and blood flow monitoring using PDMS layer were also demonstrated. The second part of the work, presents contributions towards the electronic integration and packaging of large-area 2-D arrays. A very large 2D array is appealing for it can enable advanced novel imaging applications, such as a reconfigurable array, and a compression plate for breast cancer screening. With these goals in mind, I developed the first large-scale fully populated and integrated 2D CMUTs array with 32 by 192 elements. In this study, I demonstrate a flexible and reliable integration approach by successfully combining a simple UBM preparation technique and a CMUTs-interposer-ASICs sandwich design. The results show high shear strength of the UBM (26.5 g), 100% yield of the interconnections, and excellent CMUT resonance uniformity ([lowercase Sigma] = 0.02 MHz). As demonstrated, this allows for a large-scale assembly of a tile-able array by using an interposer. Interface engineering is crucial towards the development of CMUTs into a practical ultrasound system. With the advances in encapsulation technique with a viscoelastic polymer and the combination of the UBM technique to the TSV fabrication for electronics integration, a fully integrated CMUT system can be realized.
  • 2012 Springer
    K. Sasaki, O. Suzuki, N. Takahashi, editors ; P. Stashenko, ... [et al.], associate editors.
  • 2015 Springer
    Keiichi Sasaki, Osamu Suzuki, Nobuhiro Takahashi, editors.
    The Tohoku University Graduate School of Dentistry first introduced the concept of ℓ́ℓInterface Oral Health Scienceℓ́ℓ, designed to establish and maintain healthy oral cavities, which are home to a number of mixed systems. Included in those systems are: (1) host tissues such as teeth, mucosa, muscle and bone, (2) parasites and microorganisms cohabiting the surfaces of the oral cavity, and (3) biomaterials that are used for the rehabilitation of oral functions. In addition, (4) these systems are subject to severe and complex mechanical forces. Therefore, it is critical to promote dental studies that integrate a wide range of interdisciplinary research as medicine, agriculture, material science, engineering, and pharmacology. With this incentive, international symposiums for interface oral health science have been held several times in the past. The concept has since refined and expanded, the result being the ℓ́ℓBiosis-Abiosis Intelligent Interface,ℓ́ℓ and projects aiming at the creation of highly functional and autonomic intelligent interfaces are ongoing. This book brings together a number of studies on incentives and projects by leading authors. Topics include biosis-abiosis interface of dental implants, biomaterials in interface science, biomedical engineering interface, and cell manipulation and tissue regeneration. Readers not only from the field of dentistry but also many related areas will find this book a valuable resource.
  • 2010 Springer
    T. Sasano, O. Suzuki, editors ; P. Stashenko ... [et al.], associate editors.
  • 2007 Springer
    Paula M. Pitha, ed.
    Also available: Print – 2007
  • 2005 Springer Protocols
    edited by Daniel J.J. Carr.
    Also available: Print – 2005
  • ScienceDirect
    edited by Sidney Pestka.
    Also available: Print – 1981
  • ScienceDirect
    edited by Sidney Pestka.
    Also available: Print – 1981
  • ScienceDirect
    edited by Sidney Pestka.
    Also available: Print – 1986
  • 2014 Springer
    Simon Fillatreau, Anne O'Gara, editors.
    " This volume provides a set of reviews dedicated to the biology of Interleukin (IL)-10. It includes chapters on its importance for maintaining immune homeostasis in humans, its role in intestinal immunity and its functions during viral and bacterial infections. In addition, it presents reviews on the mechanisms linking innate microbial recognition to the production of IL-10 and on how IL-10 recognition by its receptor functions. The roles of T and B cells as relevant sources of IL-10 are also discussed, with an emphasis on the clinical opportunities offered by IL-10-producing Tr1 cells for the suppression of unwanted immunity. Finally, the functions of other cytokines of the IL-10 family are presented. Collectively, these articles provide a comprehensive overview of our current knowledge on one of the most important anti-inflammatory cytokines known to date."--Publisher's website.
  • 2014 ScienceDirect
    Arseniy E. Yuzhalin, Anton G. Kutikhin.
    Introduction : basic concepts -- Interleukin-1 superfamily and cancer -- Interleukin-2 superfamily and cancer -- Interleukin-3, Interleukin-5, and cancer -- IL-6 family and cancer -- Interleukin-10 superfamily and cancer -- Interleukin-12 superfamily and cancer -- Interleukin-17 superfamily and cancer -- The rest of interleukins -- Concluding remarks.
  • 2008
    Bryan E. Bledsoe, Robert S. Porter, Richard A. Cherry, Scott R. Snyder.
    Status: Not Checked OutLane Catalog Record
  • 2016 ScienceDirect
    edited by Katherine L. Wilson, Arnoud Sonnenberg.
    BioID identification of lamin-associated proteins -- Proximity-dependent biotin identification (BioID) in Dictyostelium Amoebae -- Purification and structural analysis of LEM-domain proteins -- Purification and structural analysis of SUN and KASH domain proteins - Purification and lamins and soluble fragments of NETs -- Simple separation of functionally distinct populations of lamin-binding proteins -- Development of a novel green fluroescent protein-based binding assay to study the association of plakins with intermediate filament proteins -- Functional analysis of keratin-associated proteins in intestinal epithelia: heat-shock protein chaperoning and kinase rescue -- Purification of protein chaperones and their functional assays with intermediate filaments -- Purification and structural analysis of plectin and BPAG1e -- Purification and structural analysis of desmoplakin -- Degradation of the intermediate filament family by gigaxonin -- Functional and genetic analysis of plectin in skin and muscle -- Functional and genetic analysis of epiplakin in epithelial cells -- In vitro model of the epidermis: connecting protein function to 3D structure -- Functional analysis of periplakin and envoplakin, cytoskeletal linkers, and cornified envelope precursor proteins -- Microtubule-actin cross-linking factor 1: domains, interaction partners, and tissue-specific functions -- Functional and genetic analysis of neuronal isoforms of BPAG1 -- Functional and genetic analysis of spectraplakins in Drosophila -- Functional and genetic analysis of VAB-10 spectraplakin in Caenorhabditis elegans -- Tagged chromosomal insertion site system: a method to study lamina-associated chromatin -- Lamin-binding proteins in caenorhabditis elegans -- Pathologically relevant prelamin A interactions with transcription factors -- MCLIP detection of novel protein-protein interactions at the nuclear envelope -- Preparation of the human cytomegalovirus nuclear egress complex and associated proteins.
  • 2016 ScienceDirect
    edited by M. Bishr Omary and Ronald K.H. Liem.
    Intermediate Filament Proteins, the latest volume in the Methods in Enzymology series covers all the intermediate filaments in vertebrates and invertebrates, providing a unique understanding of the multiple different tissue-specific intermediate filaments. This volume also covers the latest methods that are currently being used to study intermediate filament protein function and dynamics. It will be an important companion for any experimentalist interesting in studying this protein family in their cell or organism model system.
  • 2006 Springer
    [edited by] Jesús M. Paramio.
    Desmin and other intermediate filaments in normal and diseased muscle / Denise Paulin and Zhigang Xue -- Intermediate filaments in astrocytes in health and disease / Milos Pekny and Ulrika Wilhelmsson -- Neuronal intermediate filaments and neurodegenerative diseases / Gee Y. Ching and Ronald K.H. Liem -- Neurofilaments: phosphorylation and signal transduction / Sashi Kesavapany, Richard H. Quarles and Harish C. Pant -- Keratin intermediate filaments and diseases of the skin / E. Birgitte Lane -- The keratin K6 minifamily of genes / Manuel Navarro -- Transcriptional regulation of keratin gene expression / Miroslav Blumenberg -- Simple epithelial keratins: expression, function and disease / M. Llanos Casanova, Ana Bravo and José L. Jorcano -- Keratins as targets in and modulators of liver diseases / Kurt Zatloukal ... [et al.] -- The search for specific keratin functions: the case of keratin K10 / Mirentxu Santos ... [et al.].
  • 2006 ProQuest Safari
    Randal L. Schwartz, Brian D. Foy, and Tom Phoenix.
    Also available: Print – 2006
  • 2006
    John D. Enderle, David C. Farden, Daniel J. Krause.
  • 2002 HighWire
    edited by G. Brevetti.
    Also available: Print – 2002
  • 2012 Springer
    Lei Xi, Tatiana V. Serebrovskaya, editors.
    Part 1. Intermittent Hypoxia and Cardiovascular Disorders -- Sleep-Disordered Breathing and Cardiac Arrhythmias: Role of Intermittent Hypoxia / Thomas Bitter -- Effects of Chronic Intermittent Hypoxia on Cardiac Rhythm Transcriptomic Networks / Sanda Iacobas and Dumitru Andrei Iacobas -- Intermittent Hypoxia and Atherosclerosis / Demet Tekin, Elisa Chong and Lei Xi -- Protective Effects of Chronic Intermittent Hypoxia Against Myocardial Ischemia/Reperfusion Injury / Huang-Tian Yang, Yi Zhang, Zhi-Hua Wang and Zhao-Nian Zhou -- Role of Mitochondrial Permeability Transition Pore in Intermittent Hypoxia-Induced Cardiac and Neuronal Protection / Galina Vavilova, Tatyana Shimanskaya, Nataliya Strutynska, Sergey Talanov and Vadim Sagach -- Intermittent Hypoxia Alters the Function of Cardiovascular Neurons and Reflex Pathways in the Brainstem / David D. Kline and David Mendelowitz. Part 2. Intermittent Hypoxia and Respiratory Disorders -- Effect of Intermittent Hypoxia on Breathing Stability in Individuals with Sleep Apnea / Jason H. Mateika -- Activation of Inflammatory Circulating Factors by Intermittent Hypoxia in Sleep Apnea Syndrome / Larissa Dyugovskaya and Andrey Polyakov -- Beneficial Effects of Intermittent Normobaric Hypoxic Training on Respiratory Function in Patients with Chronic Pulmonary Diseases / Mikhail I. Levashov -- Effects of Intermittent Hypoxic Training on Exercise Tolerance in Patients with Chronic Obstructive Pulmonary Disease / Martin Burtscher -- Intermittent Hypoxia in Treatment of Bronchial Asthma in Childhood / Tatiana V. Serebrovskaya, Alexander N. Bakunovsky, Klaudia V. Nesvitailova and Iryna N. Mankovska. Part 3. Intermittent Hypoxia and Neurological Disorders -- Intermittent Hypoxia and Experimental Parkinson's Disease / Maria V. Belikova, Evgenia E. Kolesnikova and Tatiana V. Serebrovskaya -- Protective Effects of Adaptation to Hypoxia in Experimental Alzheimer's Disease / Eugenia B. Manukhina, Anna V. Goryacheva, Maya G. Pshennikova, Igor Yu. Malyshev and Robert T. Mallet, et al. -- Neuroprotective Mechanisms of Intermittent Hypoxia: An In Vitro Study / Galina Skibo, Maxim Orlovsky, Anastasiia Maistrenko, Victor Dosenko and Iryna Lushnikova. Part 4. Intermittent Hypoxia and Occupational, Environmental, and Other Disorders -- Intermittent Hypoxic Training to Enhance Endurance in Elite Swimmers / Nikolai I. Volkov -- Adaptation to Intermittent Hypoxia/Hyperoxia Enhances Efficiency of Exercise Training / Tatyana G. Sazontova, Antonina V. Bolotova, Irina V. Bedareva, Nadezhda V. Kostina and Yuriy V. Arkhipenko -- Hypobaric Interval Hypoxia as a Nonmedication Method for Improving the Functional State of Aerospace Pilots and Astronauts / Igor B. Ushakov, Anatoli A. Shishov, Vladimir N. Komarevtsev and Vladimir N. Filatov -- Intermittent Hypoxia Remedies Male Subfertility / R. James Swanson and Zoya Serebrovska -- Anticancer Effects of Intermittent Hypoxia in Acute Myeloid Leukemia / Guo-Qiang Chen and Wei Liu -- Energotropic Effects of Intermittent Hypoxia: Role of Succinate-Dependent Signaling / Ludmila D. Lukyanova, Yu I. Kirova and Elina L. Germanova -- Intermittent Hypoxia and Health: From Evolutionary Aspects to Mitochondria Rejuvenation / Arkadi F. Prokopov. Part 5. Methods and Equipment for Therapeutic use of Intermittent Hypoxia in Humans -- Benefits and Risks of Different Regimen of Intermittent Hypoxic Training / Katerina Rozova, Olga Gonchar and Iryna N. Mankovska -- Individualized Intermittent Hypoxia Training: Principles and Practices / Tatiana V. Serebrovskaya and Lei Xi -- Hypoxicators: Review of the Operating Principles and Constructions / Viktor A. Lopata and Tatiana V. Serebrovskaya -- Method of Combined Intermittent Hypoxia and Surface Muscle Electrostimulation for Enhancing Peripheral Stem Cells in Humans / Ginés Viscor, Casimiro Javierre, Teresa Pagès, Luisa Corral and Joan Ramon Torrella, et al.
  • 2007
    Donald Resnick, Heung Sik Kang, Michael L. Pretterklieber.
    Status: Not Checked OutLane Catalog Record
  • 2007 Springer
    Jenö Manninger ... [et al.] (eds.) ; [translated from the Hungarian text to German by Dagmar Merkel ; translated from the German text by Hans K. Uhthoff with the assistance of Annegret Uhthoff].
  • 2010 Springer
    Jarrah Ali Al-Tubaikh.
  • 2007 Ovid
    edited by Robert W. Schrier.
    Allergy and clinical immunology / Stephen C. Dreskin, Henry N. Claman -- Cardiology / Simon Shakar, Ronald Zolty, JoAnn Lindenfeld -- Endocrinology, metabolism, and diabetes / Irene E. Schauer, Jane E.-B. Reusch -- Gastroenterology / William R. Brown -- Geriatrics / Laurence Robbins -- Infectious diseases / Robert T. Schooley -- Hematology and oncology / Paul Seligman -- Pulmonology / Marvin I. Schwarz -- Nephrology / Tomas Berl, Isaac Teitelbaum -- Rheumatology / Robert W. Janson.
    Also available: Print – 2007
  • 2007
    [edited by] Patrick C. Alguire.
    Status: Not Checked OutLane Catalog Record
  • 2009
    Patrick C. Alguire, editor-in-chief ; American College of Physicians, Clerkship Directors in Internal Medicine.
    Status: Not Checked OutLane Catalog Record
  • 2012 Springer
    Amol Saxena, editor.
    Distal First Metatarsal Osteotomy -- Hallux Valgus: Proximal First Metatarsal Osteotomies -- The Lapidus Procedure -- Hallux Rigidus: The Valenti Arthroplasty -- Hallux Rigidus: Distal First Metatarsal Osteotomy/Hohmann Procedure -- Hallux Rigidus: Proximal Phalangeal Osteotomy/Enclavement Procedure -- Arthrodesis of the First Metatarsophalangeal Joint -- Hallux Rigidus: First Metatarsal Head Resurfacing -- Revision Hallux Valgus Surgery -- Second Metatarsophalangeal Joint Arthropathy -- Tailor's Bunionectomy -- Surgical Treatment of Hammer Toe, Claw Toe, and Mallet Toe Deformity -- Current Techniques of Toenail Surgery -- Forefoot Trauma -- Fractures of the Calcaneus -- Fractures of the Talus -- Percutaneous Plating of Ankle Fractures -- Ankle Instability -- Insertional and Midsubstance Achilles Tendinopathy -- Peroneal Tendinopathy -- First Metatarsophalangeal Joint Sesamoidopathy -- Turf Toe Injuries -- Lisfranc's and Midfoot Injuries -- Stress Fractures of the Foot and Ankle in Athletes -- Plantar Fasciitis -- Osteochondral Lesions of the Talus -- Os Trigonum Injuries -- Syndesmosis Injuries -- Acute Repair of Ruptured Foot and Ankle Tendons in Athletic Patients -- Chronic Compartment Syndrome of Leg and Foot -- Pedal Amputations in Diabetes -- Charcot Foot and Ankle Disease -- Rheumatoid Foot Reconstruction -- The Pediatric Foot -- Surgical Treatment of Flexible Flatfoot in Adolescents with Bioabsorbable Implant -- Acquired Adult Flatfoot Deformity -- Cavus Foot -- Advances in Anterior Ankle and Subtalar Arthroscopy -- Posterior Ankle Arthroscopy and Endoscopy -- Endoscopic Gastrocnemius Recession -- The Use of External Fixation in the Lower Extremity -- Intramedullary Nail Fixation for Tibiotalocalcaneal Arthrodesis -- Total Ankle Arthroplasty: The US Experience -- Tumors and Tumor-Like Lesions of the Foot and Ankle: Diagnosis and Treatment -- Postoperative Physical Therapy for Foot and Ankle Surgery.
  • 2006
    David W. Hill.
    Status: Not Checked OutLane Catalog Record
  • 2006
    edited by Fred R. Hirsch ... [et al.].
    Status: Not Checked OutLane Catalog Record
    Global epidemiology of lung cancer -- The molecular epidemiology of lung cancer -- Tobacco, lung cancer and tobacco control -- Clinical approaches to smoking cessation -- Pathology of lung preneoplasia -- Lung carcinogenesis: biology -- Proteomic strategies for the early detection of lung cancer -- Sputum cytology and biomarkers -- The role of autofluorescence bronchoscopy in diagnosis of early lung cancer -- The role of endobronchial ultrasound (EBUS) in diagnosis and treatment of centrally located early lung cancer -- Bronchoscopic treatment of early lung cancer lesions -- CT screening for lung cancer -- New directions in spiral CT image processing and computer-aided diagnosis -- Diagnostic workup of screen-detected lesions -- The pathology of screen-detected lesions -- Surgical approaches to screen-detected lesions and tissue acquisition for translational research -- Non-surgical approaches to early-stage non-small-cell lung cancer (NSCLC) -- Economic evaluation of lung cancer screening -- Chemoprevention -- The selection of the optimal target population for spiral CT screening and chemoprevention trials.
  • 2013
    editors, April Fritz, Constance Percy, Andrew Jack, Kanagaratnam Shanmugaratnam, Leslie Sobin, D. Max Parkin, Sharon Whelan.
    Status: Not Checked OutLane Catalog Record
  • Ovid, Click on ICD-9-CM tab under Tools
    2004 Natl Cent Health Stat
    v. 1. Diseases, tabular list -- v. 2. Diseases, alphabetic index.
    Also available: Print – v. 1-2, 1991-
  • 2007
    Status: Not Checked OutLane Catalog Record
  • 2005 Springer
    Y. Kusaka, K.G. Hering, J.E. Parker (eds.).
  • NLM
    edited by S. P. Lapage, P. H. A. Sneath, E. F. Lessel ... [et al.].
    Also available: Print – 1992
  • NLM
    edited by S. P. Lapage, P. H. A. Sneath, E. F. Lessel ... [et al.].
    Also available: Print – 1992
  • v. 1, 2006 CRCnetBASE
    edited by Waldemar Karwowski.
  • 2015 ScienceDirect
    editor-in-chief: James D. Wright.
    Provides historical, foundational and interdisciplinary information across behavioral and social sciences, including psychiatry. Includes nearly 4000 articles.
  • 2014 Springer
    Andrew L. Cherry, Mary E. Dillon, editors.
    The rates are on the decline worldwide. But adolescent pregnancies still occur, placing millions of girls each year at risk for medical complications and social isolation, and their babies for severe health problems--especially when prenatal care is inadequate or nonexistent. But as the opportunity for young women and girls increases around the world, adolescent pregnancy will continue to decline. Featuring reports from countries across the developed and developing worlds, the International Handbook of Adolescent Pregnancy analyzes the scope of the problem and the diversity of social and professional responses. Its biological/ecological perspective identifies factors influencing childhood pregnancy, as well as outcomes, challenges, and needs of very young mothers as they differ across nations and regions. Salient comparisons are made as cultural contexts and community support vary widely, and attention is paid to issues such as child marriage, LGBT concerns, and the impact of religion and politics on health care, particularly access to contraception, abortion, and other services. This global coverage heightens the understanding of readers involved in care, education, and prevention programs, and otherwise concerned with the psychosocial development, reproductive health, and general well-being of girls.
  • 2012 Springer
    Michael Potegal, Gerhard Stemmler, Charles Spielberger, editors.
    Cross-disciplinary views of anger : consensus and controversy / Michael Potegal and Gerhard Stemmler -- A brief history of anger / Michael Potegal and Raymond W. Novaco -- Population and molecular genetics of anger and aggression : current state of the art / Martin Rueter -- Constructing a neurology of anger / Michael Potegal and Gerhard Stemmler -- Anger, motivation, and asymmetrical frontal cortical activations / Eddie Harmon-Jones, Carly K. Peterson, and Cindy Harmon-Jones -- The neurochemistry and psychopharmacology of anger / Alyson J. Bond and Janet Wingrove -- Somatovisceral activation during anger / Gerhard Stemmler -- The expression of anger across cultures / David Matsumoto, Seung Hee Yoo, and Joanne Chung -- Vocal expressions of anger / James A. Green, Pamela G. Whitney, and Gwen E. Gustafson -- Cross-cultural experience of anger : a psycholinguistic analysis / Zoltán Kövecses -- The development of anger / Michael Lewis -- Anger in children's tantrums : a new, quantitative, behaviorally based model / Michael Potegal and Peihua Qiu -- The development of anger from preschool to middle childhood : expressing, understanding, and regulating anger / Elizabeth A. Lemerise and Bridgette D. Harper -- Anger and the reactive-proactive aggression distinction in childhood and adolescence / Julie A. Hubbard ... [et al.] -- Why do I get angry? A componential appraisal approach / Tanja Wranik and Klaus R. Scherer -- Appraisals and anger : how complete are the usual appraisal accounts of anger? / Leonard Berkowitz -- Fuel in the fire : how anger impacts judgment and decision-making / Paul M. Litvak ... [et al.] -- State and trait anger, fear, and social information processing / David Schultz, Angela Grodack, and Carroll E. Izard -- The sociological study of anger : basic social patterns and contexts / Scott Schieman -- Anger in the context of gender / Agneta H. Fischer and Catharine Evers -- Madmen : an evolutionary perspective on anger and men's violent responses to transgression / Daniel M.T. Fessler -- The temporal dynamics of anger : phenomena, processes, and perplexities / Michael Potegal -- The nature and measurement of anger / Charles D. Spielberger and Eric C. Reheiser -- "Righteous" anger and revenge in the workplace : the fantasies, the feuds, the forgiveness / Thomas M. Tripp and Robert J. Bies -- Anger/hostility and cardiovascular disease / Janice E. Williams -- The anger of pain sufferers : attributions to agents and appraisals of wrongdoings / Ephrem Fernandez and Ajay Wasan -- Anger and psychopathology / Raymond W. Novaco -- Toward an integrative psychotherapy for maladaptive anger / Ephrem Fernandez -- The contribution of child anger and fear, and parental discipline to early antisocial behavior : an integrative model / James Snyder ... [et al.] -- Anger in intimate relationships / Donald G. Dutton -- Don't worry, be angry? Effects of anger on feelings, thoughts, and actions in conflict and negotiation / Gerben A. Van Kleef -- Anger, violence, and political science / Roger Petersen and Sarah Zukerman.
  • 2011 Springer
    Johnny L. Matson, Peter Sturmey, editors.
    Since the early 1940s, when first identified as childhood psychosis and autistic psychopathy, autism spectrum disorder (ASD) has continued to burgeon into a major focus of inquiry and interest among researchers, practitioners, and the public alike. With each passing decade, the number of scholarly articles addressing ASD and related disabilities continues to soar. Today, thousands of papers on autism are published annually across various disciplines and journals, making it challenging if not impossible to keep pace with, let alone synthesize, all the latest developments. Based on a solid historical foundation of autism theory and research, the International Handbook of Autism and Pervasive Developmental Disorders integrates the broad scholarly base of literature with a trenchant analysis of the state of the field in nosology, etiology, assessment, and treatment. Its expert contributors examine recent findings and controversies (e.g., how prevalent autism actually is), along with longstanding topics of interest as well as emerging issues. Coverage includes: A survey of diagnostic criteria and assessment strategies. Genetic, behavioral, biopsychosocial, and cognitive models. Psychiatric disorders in persons with ASD. Theory of mind and facial recognition. Diagnostic instruments for assessing core features and challenging behaviors. Evidence-based psychosocial, pharmacological, and integrative treatments. Interventions specifically for adults with ASD. Training issues for professionals and parents. A review of findings of successful and promising therapies, coupled with guidance on how to distinguish between dubious and effective treatments. The International Handbook of Autism and Pervasive Developmental Disorders is an indispensable resource for researchers, professors, graduate students, and allied practitioners in clinical child and school psychology, child and adolescent psychiatry, education, social work, rehabilitation, pediatric medicine, and developmental psychology.
  • 2009 Springer
    edited by Marian de Souza, Leslie J. Francis, James O'Higgins-Norman and Daniel G. Scott.
    Part 1. General Introduction -- Part I. The Psychology of Religion and Spirituality: Implications for Education and Wellbeing - An Introduction -- Part II. The Role of Spirituality in Human Development and Identity: An Introduction -- Part III. The Spiritual Dimension in Educational Programs and Environments to Promote Holistic Learning and Wellbeing: An Introduction.
  • 2003 CRCnetBASE
    edited by Marianne D. Miliotis, Jeffrey W. Bier.
  • 2015 Springer
    Ingrid Söderback, editor.
    Advanced therapies and technologies, new service delivery methods, and care upgrades in underserved areas are translating into improved quality of life for millions with disabilities. Occupational therapy parallels this progress at the individual level, balancing short-term recovery and adaptation with long-term independence and well-being. This Second Edition of the International Handbook of Occupational Therapy Interventions builds on its groundbreaking predecessor by modeling current clinical standards rooted in evidence-based practice. Its interventions are applied to a diverse range of client illnesses, injuries, and conditions, with new or rewritten chapters on workplace and vehicle accommodations, smart home technologies, end-of-life planning, and other salient topics. New introductory chapters spotlight core competencies in the field, from assessing client needs and choosing appropriate interventions to evaluating programs and weighing priorities. And for increased educational value, interactive case studies allow readers an extra avenue for honing clinical reasoning and decision-making skills. Intervention areas featured in the Handbook: Environmental accommodation, assistive technologies, and accessible design. Active learning to support mental, cognitive, movement- and sensory-based functioning and work-related rehabilitation programs Enabling recovery and creating opportunity. Promoting health and preventing further disability. The Second Edition of the International Handbook of Occupational Therapy Interventions is career-affirming reading for all members of rehabilitation teams, including occupational and physical therapists and rehabilitation nurses. Students intending to enter this growing field and professionals working toward its continued improvement will find it useful and inspiring.
  • 2009 Springer
    Ingrid Söderback, editor.
  • 2008 CRCnetBASE
    edited by Shlomo Giroa Shoham, Ori Beck, Martin Kett.
    Introduction -- Punishment and culture / Thomas G. Blomberg, William D. Bales, and Courtney A. Waid -- Prisons and jails / Roy D. King -- Suicide in prisons and jails / Christine Tartaro and David Lester -- Hit 'em where it hurts : monetary and nontraditional punitive sanctions / Shanna Van Slyke, Gordon P. Waldo, and William Bales -- The death penalty : the movement toward worldwide abolition / Roger Hood -- Probation, parole, and community corrections : an international perspective / Lawrence F. Travis and Victoria Simpson Beck -- Crime prevention / Steven P. Lab -- Situational crime prevention / Marcus Felson -- Early developmental crime prevention / David P. Farrington and Brandon C. Welsh -- Deterrence and deterrence experiences : preventing crime through the threat of punishment / Per-Olof H. Wikstrom -- Retribution and retaliation / John Pratt -- Reparation, compensation, and restitution : our best explanations / Charles F. Abel -- The police / Joseph A. Schafer and Clemens Bartollas -- What can police do to reduce crime, disorder, and fear? / David Weisburd and John E. Eck -- When states do not extradite : gaps in the global web of formal social control / William F. McDonald -- A comparative look at the roles and functions of the prosecution and defense in western trial systems / William T. Pizzi -- Sentencing structure and reform in common law jurisdictions / Julian V. Roberts and Estella Baker -- Victims and victimization / Ken Pease -- Restorative justice : an alternative for responding to crime? / Lode Walgrave -- The practice of victim offender mediation : a look at the evidence / Mark S. Umbreit, Robert B. Coates, and Betty Vos -- Lenient justice? punishing white-collar and corporate crime / Henry N. Pontell, Stephen M. Rosoff, and Andrew Peterson -- The third wave : American sex offender policies since the 1990s / Jonathan Simon and Chrysanthi Leon.
  • 2003 ScienceDirect
    editor, Larisa V. Shavinina.
    pt. I. Introduction -- pt. II. The nature of innovation -- pt. III. Individual differences in innovative ability -- pt. IV. Development of innovation across the life span -- pt. V. Assessment of innovation -- pt. VI. Development of innovation -- pt. VII. Innovations in different domains -- pt. VIII. Basic approaches to the understanding of innovation in social context -- pt. IX. Innovations in social institutions -- pt. X. Innovation management -- pt. XI. Innovation leadership -- pt. XII. Innovation and marketing -- pt. XIII. Innovation around the world : examples of country efforts, policies, practices and issues -- pt. XIV. Innovations of the future -- pt. XV. Conclusion.
  • 2006
    Status: Not Checked OutLane Catalog Record
  • Also available: Print – 1983
  • 2008 WHO
    "The purpose and scope of the International Health Regulations (2005) are "to prevent, protect against, control and provide a public health response to the international spread of disease in ways that are commensurate with and restricted to public health risks, and which avoid unnecessary interference with international traffic and trade". Because the IHR (2005) are not limited to specific diseases but apply to new and ever-changing public health risks, they are intended to have long-lasting relevance in the international response to the emergence and spread of disease. The IHR (2005) also provide the legal basis for important health documents applicable to international travel and transport and sanitary protections for the users of international airports, ports, and ground crossings. This second edition contains the text of the IHR (2005), the text of World Health Assembly resolution WHA58.3, the version of the Health Part of the Aircraft General Declaration that entered into force on 15 July 2007, appendices containing a list of States Parties and State Party reservations and other communications in connection with the IHR (2005)."-- back cover.
    Also available: Print – 2008
  • 2003 CRCnetBASE
    Charles B. Sidebottom.
    Pt. I. Negotiating a Common Understanding -- ch. 1. The Global Market for Healthcare Technology -- pt. II. Argentina and Brazil -- ch. 2. Argentina -- ch. 3. Brazil -- pt. III. Australia -- ch. 4. The Therapeutic Goods Act of Australia -- ch. 5. General Therapeutic Device Labeling in Australia -- ch. 6. The Therapeutic Goods Amendment of 2002 -- pt. IV. Canada and Mexico -- ch. 7. The Food and Drugs Act of Canada -- ch. 8. General Medical Device Labeling in Canada -- ch. 9. Radiation-Emitting Device Labeling in Canada -- ch. 10. Mexico -- pt. V. China, Korea, and Thailand -- ch. 11. People's Republic of China -- ch. 12. Republic of Korea -- ch. 13. Thailand -- pt. VI. European Union -- ch. 14. The European Medical Device Directives -- ch. 15. The Medical Device Directive (MDD) --ch. 16. The Active Implantable Medical Device Directive (AIMDD) -- ch. 17. The In Vitro Diagnostic Device Directive (IVDD) -- pt. VII. Japan -- ch. 18. The Pharmaceutical Affairs Law of Japan -- ch. 19. General Medical Device Labeling in Japan -- pt. VIII. United States -- ch. 20. The Federal Food, Drug, and Cosmetic Act -- ch. 21. General Device Labeling in the United States -- ch. 22. In Vitro Diagnostic Product Labeling -- ch. 23. Radiation-Emitting Device Labeling -- ch. 24. Bringing Devices to Market in the United States -- ch. 25. Good Manufacturing Practice in Labeling -- ch. 26. Special Labeling Requirements for Specific Devices in the United States -- pt. IX. Development of Device Labels -- ch. 27. Reducing Labeling Problems -- ch. 28. Designing Good Labeling -- Appendix A. U.S. Department of Commerce Medical Device Product Categories/Classification -- Appendix B. Australian Department of Health and Aging Classification of Devices -- Appendix C. International Symbols for Medical Device Marking -- Appendix D. Korean Medical Device Classification -- Appendix E. Japanese Medical Device Classification -- Appendix F. U.S. Department of Health and Human Services Medical Device Classification -- Appendix G. Useful Web Sites.
  • v. 1-, 2008- Springer
    Cutter, Anthony Mark; Gordijn, Bert; Marchant, Gary Elvin; Murphy, Colleen; Pompidou, Alain; Roeser, Sabine.
    Technologies are developing faster and their impact is bigger than ever before. Synergies emerge between formerly independent technologies that trigger accelerated and unpredicted effects. Alongside these technological advances new ethical ideas and powerful moral ideologies have appeared which force us to consider the application of these emerging technologies. In attempting to navigate utopian and dystopian visions of the future, it becomes clear that technological progress and its moral quandaries call for new policies and legislative responses. Against this backdrop this new book series from Springer provides a forum for interdisciplinary discussion and normative analysis of emerging technologies that are likely to have a significant impact on the environment, society and/or humanity. These will include, but be no means limited to nanotechnology, neurotechnology, information technology, biotechnology, weapons and security technology, energy technology, and space-based technologies.
  • 2007
    Status: Not Checked OutLane Catalog Record
  • 2013 Karger
    editors, Robert E. Black, Atul Singhal, Ricardo Uauy.
    Country-level action to improve nutrition and health : the case of Chile in the last century / Jimenez, J. -- Global, regional, and country trends in underweight and stunting as indicators of nutrition and health of populations / Neufeld, L.M., Osendarp, S.J.M. -- Global distribution and disease burden related to micronutrient deficiencies / Black, R.E. -- Predicting the health effects of switching infant feeding practices for use in decision-making / Yarnoff, B.O., Allaire, B.T., Detzel, P. -- Addressing the double burden of malnutrition with a common agenda / Uauy, R., Garmendia, M.L., Corvalán, C. -- Summary on world nutrition situation / Uauy, R. -- Interventions to address maternal and childhood undernutrition : current evidence / Bhutta, Z.A., Das, J.K. -- Maternal nutrition interventions to improve maternal, newborn, and child health outcomes / Ramakrishnan, U., Imhoff-Kunsch, B., Martorell, R. -- Fetal growth restriction and preterm as determinants of child growth in the first two years and potential interventions / Christian, P. -- How can agricultural interventions contribute in improving nutrition health and achieving the MDGs in least-developed countries? / Dorward, A. -- Long-term consequences of nutrition and growth in early childhood and possible preventive interventions / Adair, L.S. -- Summary on evidence on interventions and field experiences / Black, R.E. -- The global epidemic of noncommunicable disease : the role of early-life factors / Singhal, A. -- Obesity and the metabolic syndrome in developing countries : focus on south Asians / Misra, A., Bhardwaj, S. -- Preventing atopy and allergic disease / Heine, R.G. -- Nutrition and chronic disease : lessons from the developing and developed world / Prentice, A.M. -- Summary on future perspectives / Singhal, A.
  • 2013 WHO
    World Health Organization, ISCOS.
    1. Understanding spinal cord injury -- 2. A global picture of spinal cord injury -- 3. Prevention of spinal cord injury -- 4. Health care and rehabilitation needs -- 5. Health systems strengthening -- 6. Attitudes, relationships and adjustment -- 7. Spinal cord injury and enabling environments -- 8. Education and employment -- 9. The way forward, recommendations -- Technical appendices A-D -- Glossary -- Index.
    Also available: Print – 2013
  • 2008 CRCnetBASE
    D. Jesse Wagstaff.
  • 2013 Springer
    edited by R. Mantke, Hans Lippert, Markus W. Büchler, Michael G. Sarr.
    Surgery of the Pancreatic Carcinoma -- Basic Chapter / René Mantke, Hans Lippert -- Commentary / Claudio Bassi, Giovanni Butturini, Roberto Salvia -- Commentary / Thilo Hackert, Jens Werner, Markus W. Büchler -- Commentary / Philippe Bachellier, E. Rosso, D. Jaeck -- Commentary / Michael G. T. Raraty, John P. Neoptolemos -- Commentary / Tadahiro Takada, Keita Wada, Keiji Sano -- Commentary / Andrew L. Warshaw -- Chronic Pancreatitis Surgery -- Basic Chapter / Hans-Ulrich Schulz, René Mantke, Hans Lippert -- Commentary / David B. Adams, Katherine A. Morgan -- Commentary / P. C. Bornman -- Commentary / Thilo Hackert, Markus W. Büchler -- Commentary / Michael B. Farnell, Ashleigh L. Levendale -- Commentary / A. Fingerhut, S. V. Shrikhande, P. J. Shukla -- Commentary / Michael G. T. Raraty, John P. Neoptolemos -- Cystic Neoplasms of the Pancreas: SCN, MCN, IPMN -- Basic Chapter / Thilo Hackert, Stefan Fritz, Markus W. Büchler -- Commentary / Katherine A. Morgan, David B. Adams -- Commentary / Roberto Salvia, Marco Dal Molin, Claudio Bassi -- Commentary / C. Max Schmidt -- Commentary / Masao Tanaka -- Surgery of Acute Pancreatitis -- Basic Chapter / René Mantke, Hans-Ulrich Schulz, Hans Lippert -- Commentary / Hans G. Beger, B. M. Rau, B. Poch -- Commentary / Peter Fagenholz, Carlos Fernández-del Castillo -- Commentary / H. G. Gooszen -- Commentary / C. W. Imrie, C. R. Carter -- Commentary / Åke Andrén-Sandberg -- Commentary / Michael G. Sarr.
  • 2008 Springer
    edited by Michael Boylan.
  • pt. 1-2, 1978-79.
    Status: Not Checked OutLane Catalog Record
    pt. 1. Catalogue -- pt. 2. Index.
  • 2010- WHO
    Online version includes browsable tabular headings with search capability and instruction manual as well as links to older versions.
  • 2016 Springer
    Nicolò Scuderi, Bryant A. Toth, editors.
  • latest ed. only
    Also available: Print – <2012>
  • 1949-1970/71
    Status: Not Checked OutLane Catalog Record
  • 2009 Springer
    Melissa L. Rethlefsen, David L. Rothman, Daniel S. Mojon.
  • 2012 Springer
    Sally Gainsbury.
  • 2006 Springer
    edited by Robert L. Hampton and Thomas P. Gullotta ; research assistant, Jessica M. Ramos.
    Offers insights gained through the contributors' individual experiences in family violence prevention and intervention within the African-American community as well as their backgrounds in writing, teaching, training, and researching in this area. This work is useful to professional and clinical settings - as well as a graduate-level study.
  • 2007 Ovid
    Jacques Wallach.
    Introduction to normal values (reference ranges) -- Critical values -- Core blood analytes: alterations by diseases -- Urine -- Cardiovascular diseases -- Respiratory diseases -- Gastrointestinal diseases -- Hepatobiliary diseases and diseases of the pancreas -- Central and peripheral nervous system disorders -- Musculoskeletal and joint diseases -- Hematology -- Metabolic and hereditary disorders -- Endocrine diseases -- Genitourinary diseases -- Infectious diseases -- Autoimmune and miscellaneous diseases -- Disorders due to physical and chemical agents -- Therapeutic drug monitoring and drug effects -- Body substances.
    Also available: Print – 2007
  • 2014 Ovid
    Robert E. Hyatt, MD, Emeritus Member, Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota, Emeritus Professor of Medicine and of Physiology, Mayo Clinic College of Medicine, Rochester, Minnesota, Paul D. Scanlon, MD, Consultant, Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota, Professor of Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, Masao Nakamura, MD, Division of Pulmonary Medicine, Keihai-Rosai hospital, Fujiharamachi, Shioyagun, Tochigi, Japan.
    Spirometry : dynamic lung volumes -- Static (absolute) lung volumes -- Diffusing capacity of the lungs -- Bronchodilators and bronchial challenge testing -- Arterial blood gases -- Other tests of lung mechanics : resistance and compliance -- Distribution of ventilation -- Maximal respiratory pressures -- Preoperative pulmonary function testing -- Simple tests of exercise capacity -- Patterns in various diseases -- When to test and what to order -- Approaches to interpreting pulmonary function tests -- Illustrative cases.
  • 2009 Ovid
    Robert E. Hyatt, Paul D. Scanlon, Masao Nakamura.
    Spirometry: dynamic lung volumes -- Static (absolute) lung volumes -- Diffusing capacity of the lungs -- Bronchodilators and bronchial challenge testing -- Arterial blood gases -- Other tests of lung mechanics: resistance and compliance -- Distribution of ventilation -- Maximal respiratory pressures -- Preoperative pulmonary function testing -- Simple tests of exercise capacity -- Patterns in various diseases -- When to test and what to order -- Approaches to interpreting pulmonary function tests -- Illustrative cases.
  • 2015 ScienceDirect
    Ülo Maiväli, University of Tartu, Institute of Technology.
  • 2015 Springer
    Erik Rifkin, Andrew Lazris.
    Part I: Setting the Stage -- Shared Decision Making (SDM) -- Decision Aids -- Towards a Universal Decision Aid -- Involving the Patient in Decision Making -- BRCTs -- Part II: Case Studies Health Benefits and Risks -- Breast Cancer Screening: Mammograms -- Colon Cancer Screening with Colonoscopy -- Prostate Cancer Screening -- Screening for Lung Cancer with Spiral CT -- Health Effects of Smoking -- Exercise Stress Tests -- The Use of Warfarin in Atrial Fibrillation -- Aspirin for Prevention of Heart Disease and Stroke -- Screening for Carotid Stenoses in Asymptomatic Patients -- Cholesterol Screening -- Statins, Cholesterol and Coronary Heart Disease -- Annual Exam -- Screening for and Treating Dementia -- Osteoporosis: Bone Density Testing and Drug Treatment -- Osteoporosis: Calcium and Vitamin D -- Estrogen Replacement Therapy -- Vitamins and Supplements -- MRI and Back Pain -- Antibiotics in Sinusitis and Bronchitis -- Final Thoughts.
  • 2006
    Stephen H. Gehlbach.
    Status: Not Checked OutLane Catalog Record
  • 2015 Springer
    C. Scott Smith, Winslow G. Gerrish, William G. Weppner.
  • 2012 Wiley
    edited by Sarah G. Dean, Richard J. Siegert, William J. Taylor.
    Introduction : interprofessional rehabilitation -- a person-centred approach / Richard J. Siegert, William Taylor, and Sarah G. Dean -- A rehabilitation framework : the international classification of functioning, disability and health / William J. Taylor and Szilvia Geyh -- An interprofessional approach to rehabilitation / Sarah G. Dean and Claire Ballinger -- Processes in rehabilitation / William Levack and Sarah G. Dean -- Outcome measurement in rehabilitation / Richard J. Siegert and Jo Adams -- The person in context / Julie Pryor and Sarah G. Dean -- Conclusion : interprofessional rehabilitation a person-centred approach / Sarah G. Dean, Richard J. Siegert, and William J. Taylor.
  • 2011
    Jules J. VanDersarl.
    Cells communicate through direct contact and soluble chemical signals. Mimicking an extracellular environment requires controlling these signals at micron length scales. Integrated circuits make electronic control at these scales trivial, but fluidic control at these length scales requires very different principles. Standard microfluidic devices can finely control flowing fluids, but fluid flow affects cells in a myriad of ways. Alternatively, diffusion based chemical delivery methods tend to be crude, ill defined systems that offer very limited control. This thesis describes three distinctive platforms that combine the active spatial and temporal control of microfluidic systems with a delivery system that relies purely on diffusion. First, we detail a silicon based array of nanoreservoirs underneath the cell culture surface which are used to store and release bioactive molecules. These reservoirs are opened and closed with electrochemical dissolution and deposition at a narrow reservoir opening. Next, we describe an adaptation of traditional, elastomer based microfluidics. In these devices the cell culture area is separated from a microfluidic channel located directly underneath the chamber by a nanoporous membrane. The desirable microfluidic properties, including temporal and spatial control, are preserved, while fluidic flow over the cells is eliminated. Finally, we demonstrate a novel "nanostraw" culture surface, which is combined with the previous device to offer fluidic access directly to the cell cytosol, creating a powerful tool with implications for cell delivery and sampling. Additional work on probing the assembly of protein structures is also detailed. Clathrin 2-dimensional lattice assembly on lipid monolayers, serving as cell membrane mimics, was monitored and studied through surface rheological techniques. Rheological measurements elucidated important network properties, and the formation process was compared to various models for clathrin network assembly.
  • 2005 Springer
    edited by Francisco J. Villarreal.
  • 2013 Springer
    György Kovács, Peter Hoskin, editors.
    Prostate brachytherapy has been the subject of heated debate among surgeons and the proponents of the various brachytherapy methods. This very first interdisciplinary book on the subject provides a comprehensive overview of innovations in low dose rate (LDR), high dose rate (HDR), and pulsed dose rate (PDR) interstitial brachytherapy for the management of local or locally advanced prostate cancer. In addition to detailed chapters on patient selection and the use of imaging in diagnostics, treatment guidance, and implantation control, background chapters are included on related medical physics issues such as treatment planning and quality assurance. The results obtained with the different treatment options and the difficult task of salvage treatment are fully discussed. All chapters have been written by internationally recognized experts in their fields who for more than a decade have formed the teaching staff responsible for the successful GEC-ESTRO/EAU Prostate Brachytherapy Teaching Course. This book will be invaluable in informing residents and others of the scientific background and potential of modern prostate brachytherapy. It will also prove a useful source of up-to-date information for those who specialize in prostate brachytherapy or intend to start an interstitial brachytherapy service.
  • 2008
    edited by Joseph P. Lynch III.
    Status: Not Checked OutLane Catalog Record
  • 2013 CRCnetBASE
    edited by Ding-Geng Chen, Jianguo Sun, Karl E. Peace.
    "Preface The aim of this book is to present in a single volume an overview and latest developments in time-to-event interval-censored methods along with application of such methods. The book is divided into three parts. Part I provides an introduction and overview of time-to-event methods for interval-censored data. Methodology is presented in Part II. Applications and related software appear in Part III. Part I consists of two chapters. In Chapter 1, Sun and Li present an overview of recent developments, with attention to nonparametric estimation and comparison of survival functions, regression analysis, analysis of multivariate clustered- and analysis of competing risks interval-censored data. In Chapter 2, Yu and Hsu provide a review of models for interval-censored (IC) data, including: independent interval censorship models, the full likelihood model, various models for C1, C2, and MIC data as well as multivariate IC models. Part II consists of seven chapters (3-9). Chapters 3, 4 and 5 deal with interval-censored methods for current status data. In Chapter 3, Banerjee presents: likelihood based inference, more general forms of interval censoring, competing risks, smoothed estimators, inference on a grid, outcome misclassi- cation, and semiparametric models. In Chapter 4, Zhang presents regression analyses using the proportional hazards model, the proportional odds model, and a linear transformation model, as well as considering bivariate current status data with the proportional odds model. In Chapter 5, Kim, Kim, Nam and Kim develop statistical analysis methods for dependent current status data and utilize the R Package CSD to analyze such data"-- Provided by publisher.
  • 2007 Springer
    R. Merkel ... [et al.].
  • 2006
    Benjamin Douglass Hoehn.
    Status: Not Checked OutLane Catalog Record
  • 2013
    Robert H. Blank.
    The human brain : an introduction -- Brain intervention : state of the art -- Neuroethics and neuropolicy -- Implications for political behavior : addiction, sex differences, and aggression -- Individual responsibility and the criminal justice system -- Implications for social behavior, racism, and conflict -- The media, commercial and military applications and public policy -- Neuroscience and the definition of death -- Politics and the brain.
  • v. 1-5, 2012. ClinicalKey
    v. 1 ClinicalKey
    v. 2 ClinicalKey
    v. 3 ClinicalKey
    v. 4 ClinicalKey
    v. 5 ClinicalKey
    Deer, Timothy R.
  • 2010 Karger
    volume editors, Klaus Mönkemüller, C. Mel Wilcox, Miguel Muñoz-Navas.
    "The aim of this book is to present a concise yet instructive overview of the most common interventional and therapeutic gastrointestinal endoscopic procedures. Although there exists a large amount of literature dealing with therapeutic endoscopy, this publication stands out for several reasons: To begin with, it has been written by a highly selected group of international experts who contribute their own tried and tested tips and tricks. The various techniques are described in a homogeneous fashion, making it easy for the endoscopist to single out the important aspects for his or her own practice. Moreover, the data presented follows evidence-based guidelines, but does not inundate the reader with confusing facts and numbers. Finally, the book is illustrated like an atlas, featuring real-life pictures enhanced by explanatory drawings and algorithms." "This textbook is directed at residents, fellows, gastroenterologists and surgeons interested in therapeutic endoscopy. As the majority of the procedures described are classics that have stood the test of time, it will be a useful companion for many years to come."--BOOK JACKET.
  • 2010 Thieme Book
    Uwe Fischer, Friedemann Baum ; with contributions by Friedemann Baum [and others].

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