- G protein coupled receptors. Modeling, activation, interactions and virtual screening — Genetic and biochemical analysis of the Ribonuclease E family of proteins in Escherichia coli (165)
- Genetic and chemical studies towards the mechanistic understanding of Gli activation — Geriatric rheumatology : a comprehensive approach (165)
- Geriatric trauma and critical care — Good doctor : a father, a son, and the evolution of medical ethics (165)
- Good manufacturing practices for pharmaceuticals : a plan for total quality from manufacturer to consumer. 5th ed., rev. and expanded. — Gynecological imaging : a reference guide to diagnosis (162)
- 2014 Springeredited by Jay A. Yelon, Fred A. Luchette.Geriatric Trauma and Critical Care provides a multidisciplinary overview of the assessment and management of the elderly patient presenting with surgical pathology. By utilizing current literature and evidence-based resources, the textbook elucidates the unique nature of caring for the elderly population. The structure of the volume provides the reader with an overview of the physiologic and psychological changes, as well as the impact on the healthcare system, associated with the aging process. Emphasis is placed on the impact of aging, pre-existing medical problems, effects of polypharmacy, advanced directives and end-of-life wishes on acute surgical problems, including trauma and surgical critical care. Special attention is given to the ethical implications of management of the aged. The multidisciplinary contributors provide a unique point of view not common to surgical texts. The textbook is the definitive resource for practicing surgeons, emergency medicine physicians, intensivists, anesthesiologists, hospitalists, geriatricians, as well as surgical residents, nurses and therapists, all who care for elderly patients with surgical emergencies.
- 2014 SpringerTomas Lindor Griebling, editor.Geriatric urology represents one of the largest overall sectors of care provided within the specialty of urology. As the incidence and prevalence of many clinical urologic conditions increase significantly in older adults, the practice of urology involves a need for advanced knowledge of the basic principles of geriatrics. Geriatric Urology outlines important topics in the care of elderly urology patients. The first section covers the biology of aging, changes in the genitourinary system, and common diseases including urologic conditions that may serve as warning signs of other disorders. Section two covers geriatric syndromes and implications for urologic care including frailty, polypharmacy, dementia, , and wound healing. Urologic conditions in older adults are explored in detail including urinary incontinence, pelvic organ prolapse, urinary tract infection, nocturia, and benign prostate diseases. Other topics covered include obtaining informed consent, development of advance directives, palliative medicine and care of the dying patient. Geriatric Urology is of great value to urologists, geriatricians, internists, residents and family practitioners.
- 2015 SpringerMichael L. Malone, Elizabeth A. Capezuti, Robert M. Palmer, editors.Section One: Hospital-based models of care:1. Acute Care for Elders -- 2. Hospital Elder Life Program -- 3. The ACE Consult program -- 4.The Advanced Dementia Consult program -- 5. Acute Care for Elders (ACE) Tracker and "e-Geriatrician" telemedicine program -- 6. The NICHE program to prepare the workforce to address the needs of older patients -- Section Two: Models to address the needs of seniors in transition from hospital to home: 7. Care Transitions Intervention.-8. The Mary Naylor Advanced Practice Nurse model -- 9. Project BOOST -- Section Three: Outpatient-based models of care: 10. The GRACE model. 11. The Guided Care model -- 12. The Stanford Chronic Disease Self-Management program -- 13. Patient Centered Medical Home -- 14. Hospital at Home model -- 15. The Physician Home Visit program.-16. Geriatrics Evaluation and Management (GEM) program -- Section Four: Emergency Department models of care: 17. Geriatrics Emergency Department -- the GEDI WISE program -- Section Five: Models which address the needs of vulnerable populations: 18. The Evercare program to care for vulnerable elders in skilled nursing facilities -- 19. The UCLA Dementia coordinator program -- 20. The Wisconsin Alzheimer's Institute memory assessment program. 21. Memory Care Connections and LEEPS program for early memory assessment -- Section Six: Community related- models of care: 22. Stepping On-falls prevention program -- 23. Program of All-Inclusive Care of Elders (PACE model) -- 24. Wisconsin Family Care social model to support seniors in their homes.
- 2013 SpringerTim Schedl, editor.
- 2012 Springer Protocolsedited by Wai-Yee Chan, Le Ann Blomberg.Isolation of fetal gonads from embryos of timed-pregnant mice for morphological and molecular studies -- Neonatal testicular gonocytes isolation and processing for immunocytochemical analysis -- Isolation of undifferentiated and early differentiating type a spermatogonia from pou5f1-GFP reporter mice -- Isolation of human male germ-line stem cells using enzymatic digestion and magnetic-activated cell sorting -- Isolation and purification of murine male germ cells -- Preparation of enriched mouse syncitia-free pachytene spermatocyte cell suspensions -- Revealing the transcriptome landscape of mouse spermatogonial cells by tiling microarray -- Biochemical characterization of a testis-predominant isoform of n-[alpha] acetyltransferase -- Identification of novel long noncoding RNA transcripts in male germ cells -- Methylation profiling using methylated DNA immunoprecipitation and tiling array hybridization -- Spermatogenesis in cryptorchidism -- In vitro culture of fetal ovaries: A model to study factors regulating early follicular development -- Microspread ovarian cell preparations for the analysis of meiotic prophase progression in oocytes with improved recovery by cytospin centrifugation -- In vitro maturation (IVM) of porcine oocytes -- Experimental approaches to the study of human primordial germ cells -- Investigating the origins of somatic cell populations in the perinatal mouse ovaries using genetic lineage tracing and immunohistochemistry -- DNA methylation analysis of germ cells by using bisulfite-based sequencing methods -- Gene expression in mouse oocytes by RNA-Seq.
- 2008 Springer Protocolsedited by Steven X. Hou, Shree Ram Singh.pt. I. Identification and regulation of germline stem cells in model organisms -- The development of germline stem cells in Drosophila / David A. Dansereau and Paul Lasko -- Analysis of the C. elegans germline stem cell region / Sarah L. Crittenden and Judith Kimble -- Immunohistological techniques for studying the Drosophila male germline stem cell / Shree Ram Singh and Steven X. Hou -- Genetic tools used for cell lineage tracing and gene manipulation in Drosophila germline stem cells / Wei Liu and Steven X. Hou -- Structural polarity and dynamics of male germline stem cells in an insect (milkweed bug Oncopeltus fasciatus) / David C. Dorn and August Dorn -- High-resolution light microscopic characterization of spermatogonia / Hélio Chiarini-Garcia and Marvin L. Meistrich -- Identification and characterization of spermatogonial subtypes and their expansion in whole mounts and tissue sections from primate testes / Jens Ehmcke and Stefan Schlatt -- Epigenetic control in male germ cells : a transillumination-assisted microdissection method for the analysis of developmentally regulated events / Durga Prasad Mishra and Paolo Sassone-Corsi -- GDNF maintains mouse spermatogonial stem cells in vivo and in vitro / Hannu Sariola and Tiina Immonen -- g pt. II. In vitro culture and application of germline stem cells -- Ectopic grafting of mammalian testis tissue into mouse hosts / Ina Dobrinski and Rahul Rathi -- Spermatogonial stem cell transplantation, testicular function, and restoration of male fertility in mice / Derek J. McLean -- Isolating highly pure rat spermatogonial stem cells in culture / F. Kent Hamra ... [et al.] -- Deriving mouse spermatogonial stem cell lines / Ilaria Falciatori ... [et al.] -- Production of knockdown rats by lentiviral transduction of embryos with short hairpin RNA transgenes / Christina Tenenhaus Dann and David L. Garbers -- Testicular germ cell tumors in mice : new ways to study a genetically complex trait / Jason D. Heaney and Joseph H. Nadeau -- Study origin of germ cells and formation of new primary follicles in adult human and rat ovaries / Antonin Bukovsky ... [et al.].
- 2009 SpringerErlene Rosowsky, Joseph M. Casciani, Merla Arnold, editors.Policies and Reimbursement: Meeting the Need for Mental Health Care in Long-Term Care / Margaret Norris -- Referrals / Michael Smith -- Assessment / Barry A. Edelstein, Lynn E. Northrop and Lisa M. MacDonald -- Treatment Plans / Deborah W. Frazer -- Treatment Process / Michael Duffy -- Integration of Psychology, Psychiatry, and Medication in Long-Term Care / Lee Hyer and Shalija Shah -- Professional Practice: Disciplines, Documentation, and Outcomes Measurement / Merla Arnold, John C. Colletti and Nicholas C. Stilwell -- Ethical Issues in Long-Term Care / Michele J. Karel.
- v. 1-2, 1906-11. Google BooksFulltext (v. 2 pt. 1 1911) Google BooksNeuburger, Max.Also available: Print – v. 1-2, 1906-11.
- v. 1, 1940.... von Dozent Dr. Wilhelm Thomsen ... ; mit einem Geleitwort von Prof. Dr. Georg Hohmann ...I. T. Die Ideen Hermann von Meyer's über die Schuhfrage auf Grund seiner Originalschriften.
- Insa Eschebach, Astrid Ley (Hrsg.).
- 2010 Springeredited by Catherine Kim, Assiamira Ferrara.Hyperglycemia and adverse pregnancy outcome (HAPO) study: an overview -- Evolution of screening and diagnostic criteria for GDM worldwide -- An overview of problems and solutions in the diagnosis and treatment of gestational diabetes -- Prevalence of GDM -- Risk factors for gestational diabetes: from an epidemiological standpoint -- Burden of GDM in developing countries -- Insulin and the placenta in GDM -- What causes gestational diabetes? -- Mechanisms underlying insulin resistance in human pregnancy and gestational diabetes mellitus -- Inflammation, adipokines, and gestational diabetes mellitus -- Lipids in gestational diabetes: abnormalities and significance -- Blood pressure in GDM -- Genetics of gestational diabetes mellitus and type 2 diabetes -- Maternal obesity and epidemiological review of pregnancy complications -- Maternal comorbidities during gestational diabetes mellitus: obstetrical complications, prematurity, and delivery -- The diabetic intrauterine environment: short and long-term consequences -- Exercise recommendations in women with gestational diabetes mellitus -- Nutrition and weight recommendations for treating gestational diabetes mellitus -- Pharmacological treatment options for gestational diabetes -- Risk for maternal postpartum diabetes -- Contraception before and after GDM -- Lactation and diabetes among women with a history of GDM pregnancy -- Emerging science: interventions in women at risk of GDM during pregnancy -- Diabetes prevention interventions for women with a history of GDM -- Diabetes control programs and policy.
- 2014 CRCnetBASEeditor, Clive J. Petry."Discussing the origins, care, and consequences of gestational diabetes mellitus (GDM), this book focuses on evidence-based medicine to highlight various aspects of this rapidly growing condition. It provides glucose requirements for fetal growth and maternal and fetal metabolism as well as insulin secretion and sensitivity in pregnancy; covers genetic risk factors, autoimmunity, interaction with obesity, and associations with fetal growth genes; presents diet therapies and the role of exercise and nutrition; and reviews the effects of rapid-, short-, and long-acting insulin, oral hypoglycemic agents in pregnancy, and clinical approaches"--Provided by publisher.
- Also available: Print – 1899.
- Get the job you want, even when no one's hiring : take charge of your career, find a job you love, and earn what you deserve!2009 ProQuest SafariFord R. Myers.The psychology of job hunting in a down market -- From desperation to career strategies for tough times -- Leveraging your core job seeker materials -- Job search tactics to use when no one's hiring -- Bulletproof career, once and for all -- Career resources.
- 2014 CRCnetBASEJames Wigley, MBBS BSc MRCS AFHEA, University Hospital Southhampton, Southhampton, UK ; Saran Shantikumar, MRCS BHF Research Fellow, Bristol Heart Institute, Bristol, UK ; Andrew Paul Monk, DPhil MRCS Academic Clinical Lecturer in Orthopaedics, University of Oxford, Oxford, UK.
- 2012 Wiley[edited by] Chris E. Stout.Differences in business structures and protections in human service private practice : which suits your practice best? / Jonathan D. Nye -- Making ends meet : financial management in private practice / David W. Ballard -- Managed care contracting : strategies for negotiating and maintaining relationships / Bridget Morehouse -- Ethical and legal aspects of private practice / Scott Hammer and Kenneth H. Kessle.
- Getting into the healthy 'CV success zone' : effective strategies to prevent cardiovascular disease ; proceedings for a symposium organized at the 2nd World Ageing and Generations Congress, St Gallen, Switzerland, September 28 th 2006 ; [Symposium Getting into the Healthy CV Success Zone]2007 HighWireed. by Anita Rieder.
- 2006 Thieme BookGeorge W. Eastman, Christoph Wald, Jane Crossin.
- Rudra Pratap.Also available: Print – 2007
- The MathWorks.
- 2013 ebrary, Limited to 1 simultaneous userSharon Meers and Joanna Strober ; foreword by Sheryl Sandberg.Machine generated contents note: Introduction -- Imagine a Full Life -- There's No Need to Choose -- Part One -- The Good News About Work: Why Two Careers Are Better Than One -- 1. Mom and Dada: How Kids Can Get More from Two Working Parents -- 2. What Your Husband Wins from a Working Wife -- 3. What Women Gain from Working Motherhood -- Part Two -- Three Truths to Bust the Myths About Work, Women, and Men -- 4. Women Don't Quit Because They Want To -- 5. Success Does Not Require 24/7 -- 6. It's Not a Fair Game -- but You Can Improve Your Odds -- Part Three -- The 50/50 Solution and How to Make It Yours -- 7. The Great Alliance: How Your Husband Solves the Work/Life Riddle -- 8. The Pre-Baby Road Trip: Mapping Out a Leave You Can Return From -- 9. The Post-Baby Uphill: Test-Driving 50/50 and Getting Back Up to Speed -- 10. Getting to 50/50: At Home, at Work, for Life -- Resources -- Notes -- Acknowledgments -- Index -- About the Authors.
- Roger Fisher and William Ury.
- 2011 Thieme Bookedited by Mohit Bhandari, Anders Joensson.Why should we publish papers? / George M. Kontakis, Peter V. Giannoudis -- Presented but never published : why research papers are not being published / Cheryl Wylie, Sheila Sprague -- What is the quality of the published orthopaedic literature? / Daniel Vena, Sheila Sprague -- Common pitfalls in the reporting of surgical results / Rudolf W. Poolman -- Overview : what to consider before you start writing / Paul Karanicolas -- Ethics in writing : maintaining credibility / Lyndsay Somerville, Dianne Bryant -- Authorship : what you should know / Rad Zdero, Emil H. Schemitsch -- When do you need a statistician? : more than just number crunchers / Jason W. Busse -- The structured abstract / Ole Brink, Lars C. Borris -- Writing an introduction / Emil H. Schemitsch, Rad Zdero -- Writing a methods section / Emil H. Schemitsch, Rad Zdero -- Results : basics of analysis / Paul Karanicolas -- Results : tables, figures, and appendices / Jacquelyn Marsh, Dianne Bryant -- How to frame a discussion / Kyle Jeray, Stephanie Tanner -- Referencing and acknowledgments / Richard Gould, Bradley Petrisor -- Author instructions / George Mathew, Sheila Sprague -- Formatting your paper : title page and more / Scott Wingerter -- Grammar police : the dos and don'ts of writing / Eric Morrison -- How to address reviewer's comments : dos and don'ts / Rad Zdero, Emil H. Schemitsch -- Getting your research accepted at scientific meetings : writing the abstract / George Mathew, Sheila Sprague -- PowerPoint presentations : tips for presenting your work / Tara M. Mastracci -- Poster presentations : preparing an effective research poster / Chad Coles -- Be consistent : present and publish the same results / Boris A. Zelle.
- 2009 SpringerHadley Wickham.Describes ggplot2, a data visualization package for R and a powerful and flexible system for creating data graphics.
- Ghost map : the story of London's most terrifying epidemic--and how it changed science, cities, and the modern world2006Steven Johnson.An account of the worst cholera outbreak in Victorian London--and an exploration of how Dr. John Snow's solution revolutionized the way we think about disease in cities. In the summer of 1854, a devastating cholera outbreak seized London just as it was emerging as a modern city: more than 2 million people packed into a ten-mile circumference, a hub of travel and commerce, continually pushing the limits of infrastructure that's outdated as soon as it's updated. Author Johnson chronicles Snow's day-by-day efforts as he risked his own life to prove how the epidemic was being spread. When he created the map that traced the pattern of outbreak back to its source, Dr. Snow didn't just solve a pressing medical riddle--he established a precedent for the way modern city-dwellers, city planners, physicians, and public officials think about the spread of disease and the development of the modern urban environment.--From publisher description.
- 2012 SpringerRoy G. Smith, Michael O. Thorner, editors.Ghrelin, the endogenous ligand for the growth hormone secretagogue (GHS) receptor, is critical in the control of food intake and energy balance. The ghrelin receptors are now known to have important physiological properties as modulators of growth hormone release, appetite, glucose homeostasis, metabolism, immune function, neurotransmitter activity, cognitive function and neurodegeneration. Bringing all of this information together in the first comprehensive text on the topic, Ghrelin in Health and Disease provides a state-of-the-art synthesis of the latest work in this area for physicians and physician-scientists. This volume addresses the unique property of ghrelin as a modulator of function. Such a property provides potential utility for safe intervention in a wide variety of disease states. Indeed as we learn more about the basic physiology of ghrelin, the potential for treating new disease targets emerge requiring validation in the clinic. Each chapter in this volume is authored by a leading investigator in the field. The introductory chapter sets the background for the book and provides a superb overview of the relevance of ghrelin to physiology, describing how the discovery of ghrelin has prompted us to completely rethink traditional physiology. The authors conclude their chapters by critically addressing the future translational aspects of ghrelin biology and outlining what key basic research and clinical questions remain to be addressed. An invaluable resource, Ghrelin in Health and Disease distinguishes itself as the first comprehensive title covering all of the molecular and clinical issues relating to ghrelin and advancing our clinical understanding of obesity, growth, and reproductive pathogenesis.
- 2012 ScienceDirectedited by Masayasu Kojima, Kenji Kangawa.History to the discovery of ghrelin / Cyril Y. Bowers -- Orphan GPCRs and methods for identifying their ligands / Morikatsu Yoshida, Mikiya Miyazato, and Kenji Kangawa -- Purification of rat and human ghrelins / Masayasu Kojima, Hiroshi Hosoda, and Kenji Kangawa -- Variety of acyl modifications in mammalian ghrelins / Takanori Ida -- Determination of nonmammalian ghrelin / Hiroyuki Kaiya ... [et al.] -- Morphological analysis of ghrelin neurons in the hypothalamus / Haruaki Kageyama, Fumiko Takenoya, and Seiji Shioda -- High-performance liquid chromatography analysis of hypothalamic ghrelin / Takahiro Sato and Masayasu Kojima -- Standard sample collections for blood ghrelin measurements / Hiroshi Hosoda and Kenji Kangawa -- From ghrelin to ghrelin's O-acyl transferase / Jesus A. Gutierrez ... [et al.] -- Enzymatic characterization of GOAT, ghrelin O-acyltransferase / Hideko Ohgusu, Tomoko Takahashi, and Masayasu Kojima -- The study of ghrelin deacylation enzymes / Motoyasu Satou and Hiroyuki Sugimoto -- Synthesis of ghrelin : chemical synthesis and semisynthesis for large-scale preparation of modified peptides / Tomohiro Makino, Masaru Matsumoto, and Yoshiharu Minamitake -- Ghrelin O-acyltransferase assays and inhibition / Martin S. Taylor ... [et al.] -- Model-based evaluation of growth hormone secretion / Johannes D. Veldhuis and Daniel M. Keenan -- Ghrelin in the control of energy, lipid, and glucose metabolism / Kristy M. Heppner ... [et al.] -- Ghrelin and the vagus nerve / Yukari Date -- Measurement of AMP-activated protein kinase activity and expression in response to ghrelin / Chung Thong ... [et al.] -- Ghrelin and gastrointestinal movement / Naoki Fujitsuka ... [et al.] -- Ghrelin acylation by ingestion of medium-chain fatty acids / Yoshihiro Nishi, Hiroharu Mifune, and Masayasu Kojima -- Islet [beta]-cell ghrelin signaling for inhibition of insulin secretion / Katsuya Dezaki and Toshihiko Yada -- Rikkunshito as a ghrelin enhancer / Hiroshi Takeda ... [et al.] -- Thermogenic characterization of ghrelin receptor null mice / Ligen Lin and Yuxiang Sun -- Transgenic mice overexpressing ghrelin or ghrelin analog / Hiroyuki Ariyasu ... [et al.] -- Therapeutic potential of ghrelin in restricting-type anorexia nervosa / Mari Hotta ... [et al.] -- Clinical application of ghrelin for chronic respiratory diseases / Nobuhiro Matsumoto and Masamitsu Nakazato -- Clinical trial of ghrelin synthesis administration for upper GI surgery / Shuji Takiguchi ... [et al.].
- 2013 Kargervolume editors, A. Benso, F.F. Casanueva, E. Ghigo, R. Granata.
- 2016 SpringerLouis M. Wong kee Song, Emmanuel C. Gorospe, Todd H. Baron, editors.Triage Sedation and Monitoring -- Peri-procedural Management of Antithrombotic Agents -- Suspected Non-variceal Upper Gastrointestinal Bleeding -- Approach to Suspected Acute Variceal Bleeding -- Suspected Small Intestinal Hemorrhage -- Suspected Lower Gastrointestinal Bleeding -- Approach to Foreign Body Ingestion, Food Impaction and Caustic Injury -- Non-endoscopic Management of Acute Mechanical Colonic Obstruction and Pseudo-obstruction -- Approach to Acute Cholangitis -- Approach to Endoscopic Adverse Events -- Endoscopic Hemostasis of Acute Non-Variceal Upper Gastrointestinal Bleeding -- Hemostasis of Acute Esophageal Variceal Bleeding -- Hemostasis of Acute Gastric Variceal Bleeding -- Hemostasis of Acute Small Intestinal Bleeding -- Hemostasis of Acute Lower GI Bleeding -- Endoscopic Management of Food Impaction and Foreign Bodies -- Endoscopic Management of Acute Colonic Obstruction and Pseudo-obstruction -- Endoscopic Management of Pancreaticobiliary Emergencies -- Endoscopic Management of Procedure-related Bleeding and Perforation.
- 2008 Springeredited by Gary B. Huffnagle, Mairi Noverr.Overview of gut immunology / Katie Lynn Mason ... [et al.] -- The commensal microbiology of the gastrointestinal tract / Janet M. Manson, Marcus Rauch and Michael S. Gilmore -- Overview of the gastrointestinal microbiota / -- Vincent B. Young and Thomas M. Schmidt -- Effects of microbiota on GI health : -- Gnotobiotic research / Robert Doug Wagner -- Positive interactions with the microbiota : probiotics / Marko Kalliomøki, Seppo Salminen and Erika Isolauri -- Negative interactions with the microbiota : IBD / Nita H. Salzman and Charles L. Bevins -- Diet, immunity, and functional foods / Lesley Hoyles and Jelena Vulevic -- Host : microbe communication within the GI tract / Christopher A. Allen and Alfredo G. Torres -- Host : microbe symbiosis : the squid, vibrio association : a naturally occurring, experimental model of animal/bacterial partnerships / Margaret McFall-Ngai -- The "microflora hypothesis" of allergic disease / Andrew Shreiner, Gary B. Huffnagle and Mairi C. Noverr -- The damage : response framework of microbial pathogenesis and infectious diseases / Liise-anne Pirofski and Arturo Casadevall.Also available: Print – 2008
- von Sabine Herrmann.
- Giant magnetoresistive nanosensors for ultrasensitive in vitro diagnostics and biomolecular kinetics2011Richard S. Gaster.Nanotechnology has the unique capability of manipulating and sensing matter at the molecular scale with unprecedented speed, sensitivity, and throughput. The medical application of nanotechnology, nanomedicine, has leveraged nanoscience tools for the advancement of medical diagnostics, therapy, and basic science research. In this work, arrays of magnetically responsive nanosensors, originally developed for use as read heads in computer hard disk drives, have been utilized to achieve in-depth proteomic studies for the advancement of medical diagnostics and therapy. In particular, this dissertation will focus on the following four topics of applying magnetic nanotechnology to science and medicine. First, the application of magnetic nanosensor arrays to early cancer diagnostics and monitoring response to chemotherapy. The utility of magnetic nanosensors as a molecular diagnostics tool capable of profiling a patient's disease state and leveraging a patient's unique molecular signature will be demonstrated. Second, this report will discuss a novel mathematical model expressly developed to describe the kinetic interactions of magnetically labeled biomolecules binding to capture agents immobilized on a surface. Third, a novel autoassembly immunoassay capable of screening for antibody cross-reactivity in a high-density, high-fidelity, and rapid manner will be described. Finally, this report will address the utility of the autoassembly immunoassay in conjunction with a miniaturized magnetic nanosensor platform for point-of-care diagnostics in a cost-effective and easy-to-use (e.g. wash-free) process that can make a significant contribution to global health.
- 2011 SpringerHugo D. Luján, Staffan Svärd, editors.1. Taxonomy of Giardia species -- 2. Epidemiology of giardiasis in humans -- 3. Waterborne and environmentally-borne giardiasis -- 4. Giardia in pets and farm animals, and their zoonotic potential -- 5. Genomics of Giardia -- 6. The glycoproteins of Giardia -- 7. Mass spectrometric analysis of phospholipids and fatty acids in Giardia lamblia -- 8. Giardia metabolism -- 9. The ultrastructure of Giardia during growth and differentiation -- 10. Cell cycle regulation and cell division of Giardia -- 11. The Giardia mitosomes -- 12. Signaling pathways in Giardia lamblia -- 13. Transcription and recombination of Giardia -- 14. Intracellular protein trafficking -- 15. Post-transcriptional gene silencing and translation in Giardia -- 16. Antigenic variation of Giardia -- 17. Interaction of Giardia with host cells -- 18. Primary microtubule structures in Giardia -- 19. Pathophysiological processes and clinical manifestations of Giardiasis -- 20. Immunology of giardiasis -- 21. Vaccination against Giardia -- 22. Diagnosis of human giardasis -- 23. Methods for Giardia culture, cryopreservation, encystation, and excystation in vitro -- 24. Synchronization of Giardia -- 25. Methods for Giardia transfection and gene expression -- 26. Biological resource centers for Giardia research.
- Brene Brown.
- 2010 ebrary, Limited to 1 simultaneous userby Brené Brown.In this work, the author, a leading expert on shame, authenticity, and belonging, shares ten guideposts on the power of wholehearted living, a way of engaging with the world from a place of worthiness.
- 2015 ClinicalKey[edited by] Peter R. McNally.Swallowing disorders and dysphagia -- Gastroesophageal reflux disease -- Esophageal causes of chest pain -- Achalasia -- Esophageal cancer -- Esophageal anomalies, infections, and nonacid injuries -- Barrett's esophagus -- Esophageal and stomach pathology -- Gastritis, peptic ulcer disease, NSAIDs, and Helicobacter pylori infection -- Gastric cancer -- Thickened gastric folds -- Gastroparesis -- Evaluation of abnormal liver tests -- General concepts on viral hepatitis -- Antiviral therapy for hepatitis C -- Antiviral therapy for hepatitis B -- Autoimmune hepatitis : diagnosis -- Autoimmune hepatitis : treatment -- Primary biliary cirrhosis and primary sclerosing cholangitis -- Vaccinations and immunoprophylaxis in gastrointestinal and liver disorders -- Pregnancy and liver disease -- Rheumatologic manifestations of hepatobiliary diseases -- Evaluation of focal liver masses -- Drug-induced liver disease -- Alcoholic liver disease, alcoholism, and alcohol withdrawal syndrome -- Vascular liver disease -- Nonalcoholic fatty liver disease and nonalcoholic steatohepatitis -- Liver transplantation -- Ascites -- Liver abscess -- Inheritable forms of liver disease -- Liver histopathology -- Hepatobiliary cystic disease -- Gallbladder disease : stones, crystals, and sludge -- ERCP plus sphincter of Oddi dysfunction -- Acute pancreatitis -- Chronic pancreatitis -- Pancreatic cancer -- Cystic lesions of the pancreas -- Celiac disease -- Crohn's disease -- Ulcerative colitis -- Eosinophilic gastrointestinal disease and eosinophilic esophagitis -- Small intestinal bacterial overgrowth -- Colon disorders and colon cancer -- Constipation and fecal incontinence -- Diverticulitis -- Diseases of the appendix -- Colitis : pseudomembranous, microscopic, and radiation -- Upper gastrointestinal hemorrhage -- Lower gastrointestinal tract bleeding -- Occult and obscure gastrointestinal bleeding -- Evaluation of acute abdominal pain -- Evaluation of acute infectious diarrhea -- Chronic diarrhea -- Aids and the gastrointestinal tract -- Ischemic bowel disease -- Nutrition, malnutrition, and probiotics -- Small bowel and colon pathology -- Foreign bodies and the gastrointestinal tract -- Functional gastrointestinal disorders and irritable bowel -- Endoscopic cancer screening and surveillance -- Rheumatologic manifestations of gastrointestinal diseases -- Dermatologic manifestations of gastrointestinal disease -- Endocrine aspects of gastrointestinal system -- Plain film, barium, and virtual radiography -- Interventional radiology I : cross-sectional imaging procedures -- Interventional radiology II : fluoroscopic and angiographic procedures -- Noninvasive GI imaging : ultrasound, computed tomography, and magnetic resonance imaging -- Nuclear imaging -- Endoscopic ultrasound -- Advanced therapeutic endoscopy -- Esophageal surgery -- Surgery for peptic ulcer disease -- Surgical approach to the acute abdomen -- Colorectal surgery : polyposis syndromes and inflammatory bowel disease -- Obesity and surgical weight loss -- Minimally invasive surgery -- Clinical vignettes.
- 2010[edited by] Peter R. McNally.
- 2006[edited by] Peter R. McNally.
- 2009 Springer[edited by] Paul Goetz, Patrick Stoltz, Dominique Delaporte ; préfacé par Alain Drouard.
- 2010 Springer[edited by] Jon E.Grant, Marc N. Potenza ; edizione italiana a cura di Massimo Clerici ; [traduzione a cura di Lara Bellardita].
- 2008 ebraryEileen Miller ; illustrations by Kim Miller ; foreword by Robert Nickel.
- 2010 CRCnetBASEedited by Ric Skinner.Introduction : the evolving role of geographic information systems in hospital and healthcare emergency management / Ric Skinner -- A spatial approach to hazard vulnerability analysis by healthcare facilities / Ric Skinner -- Using GIS to improve workplace and worker safety crisis management / Jeffrey Miller -- Infectious disease surveillance and GIS : applications for emergency management / Michael Olesen -- Role of GIS in interagency healthcare logistical support during emergencies / Jerry VanVactor -- Design concept for a location-based hazard vulnerability assessment tool for healthcare facilities / Ric Skinner -- Trauma center siting, optimization modeling, and GIS / Charles Branas ... [et al.] -- Healthcare facility disaster planning : using GIS to identify alternate care sites / Johnathon Mohr, J.L. Querry, and Gwenn Allen -- Multi-scale enterprise GIS for healthcare preparedness in South Carolina / Jared Shoultz ... [et al.] -- Hospital preparedness planning for evacuation and sheltering with GIS in South Carolina / Jared Shoultz ... [et al.] -- Making sense out of chaos : improving prehospital and disaster response / Elizabeth Walters, Stephen Corbett, and Jeff Grange -- Disaster preparedness for influenza at a community hospital network : a case study / Edward Rafalski ... [et al.] -- Disaster preparedness and response for vulnerable populations : essential role of GIS for emergency medical services during the San Diego County 2007 firestorm / Isabel Corcos... [et al.] -- Natural disasters and the role of GIS in assessing need / Omar Ha-Redeye -- GIS application and a regionalized approach for mass casualty incident planning / Deborah Kim ... [et al.] -- Building a GIS common operating picture for integrated emergency medical services and hospital emergency management response / Frank Zanka.
- 2011 SpringerElisabetta de Lutio di Castelguidone, Antonella Messina, editors ; forewords by Nicholas C. Gourtsoyiannis, Antonio Rotondo, Alfredo Siani.
- Giving death a helping hand : physician-assisted suicide and public policy. An international perspective2008 Springeredited by Dieter Birnbacher and Edgar Dahl.Should physician-assisted suicide be legalized? / Gerald Dworkin -- Slippery slopes and physician-assisted suicide / Neil Levy -- Physician-assisted suicide and the medical associations / Dieter Birnbacher -- Safe, legal, rare? Physician-assisted suicide and cultural change in the future / Margaret Pabst Battin -- Palliative options of last resort: a comparison of voluntarily stopping eating and drinking, terminal sedation, physician-assisted suicide, and voluntary active euthanasia / Timothy E. Quill, Bernard Lo, Dan W. Brock -- Physician-assisted suicide in Oregon / Linda Ganzini, Edgar Dahl -- Physician-assisted suicide in the Netherlands and Belgium / John Griffiths -- Physician-assisted suicide and the German criminal law / Gabriele Wolfslast -- Physician-assisted death: an Australian perspective / Alan Rothschild -- Assisted dying: the view from the United Kingdom / Sheila A. M. McLean -- Physician-assisted suicide: a doctor's perspective / Pieter Admiraal -- Physician-assisted suicide in Switzerland: a personal report / Elke M. Baezner-Sailer -- The European convention on human rights protects the right of suicide / Ludwig A. Minelli.
- 2015 SpringerRosemary H. Tambouret, David C. Wilbur.This volume provides a compact, concise and up-to-date resource for pathologists and clinicians who are involved in women's health. The book summarizes the incidence, epidemiology and risk factors for cervical adenocarcinoma, while reviewing the normal histology of the cervix and glandular lesions of the cervix. The cytological appearance of glandular lesions of the cervix and their mimics is amply illustrated and discussed. Management of glandular lesions is also outlined. Written by authorities in the field, Glandular Lesions of the Uterine Cervix: Cytopathology with Histologic Correlates is of great value to cytopathologists, surgical pathologists, gynecologic oncologists and surgeons.
- 2006 Ovid[edited by] Michèle G. Curtis, Shelley Overholt, Michael P. Hopkins.Hirsutism / Steven M. Strong -- Vulvovaginitis / Tracey A. Banks and Michèle G. Curtis -- Sexually transmitted diseases / Lisa M. Hollier -- Chronic pelvic pain / John F. Steege -- Endometriosis / John M. Storment -- Preconception evaluation and counseling / Justin P. Lavin, Jr. and John Stewart, Jr. -- Contraception / Anthony DelConte -- Infertility and recurrent pregnancy loss / John M. Storment -- Surgical and medical abortion / Mitchell D. Creinin -- Urogynecology and pelvic floor dysfunction / Alfred E. Bent -- Lifestyle modification / Jimmy D. Acklin -- Integration of complementary and alternative medicine in the gynecology office / Michèle G. Curtis -- Intimate partner violence / Abbey B. Berenson -- Women and sexuality / Gretchen Gross -- Psychiatric disorders / James M. Martinez and Lauren B. Marangell -- Management of the HIV-positive woman / Nancy L. Eriksen -- Diagnosis and management of hereditary cancer / Monique A. Spillman and Andrew Berchuck -- Occupational and environmental exposures / Linda M. Frazier And David A. Grainger. Pediatric and adolescent gynecology / Andrea L. Zuckerman -- Care of perimenopausal and postmenopausal patients / Clarisa R. Gracia and Kurt T. Barnhart -- Lesbian, bisexual, and transgender health care / Amy E. Harrison and Vincent M. B. Silenzio -- Abnormal cytology and human papillomavirus / Barbara M. Buttin, Thomas J. Herzog, and David G. Mutch -- Benign disorders of the vulva and vagina / Wilson Sawa and Michael P. Hopkins -- Benign disorders and diseases of the breast / Daniel P. Guyton and Andrew Fenton -- Premenstrual syndromes / Meir Steiner -- Abnormal uterine bleeding / Godwin I. Meniru and Michael P. Hopkins --
- v. 2-3, 2006-09. Springer2009 Springereditors: Franz Grehn, Robert Stamper.Provides a picture of recent progress in the field of glaucoma.Also available: Print – 2006-2009
- 2008 ScienceDirectedited by Carlo Nucci, Luciano Cerulli, Neville N. Osborne and Giacinto Bagetta1. Epidemiology of primary glaucoma: prevalence, incidence, and blinding effects -- 2. Predictive models to estimate the risk of glaucoma development and progression -- 3. Intraocular pressure and central corneal thickness -- 4. Angle-closure: risk factors, diagnosis and treatment -- 5. Early diagnosis of glaucoma -- 6. Monitoring glaucoma progression -- 7. Standard automated perimetry and algorithms for monitoring glaucoma progression -- 8. Short-wavelength automated perimetry and frequency-doubling technology perimetry in glaucoma -- 9. Scanning laser polarimetry and confocal scanning laser ophthalmoscopy: technical notes on their use in glaucoma -- 10. The role of OCT in glaucoma management -- 11. Functional laser Doppler flowmetry of the optic nerve: physiological aspects and clinical applications -- 12. Advances in neuroimaging of the visual pathways and their use in glaucoma -- 13. Primary open angle glaucoma: an overview of medical therapy -- 14. The treatment of normal-tension glaucoma -- 15. The management of exfoliative glaucoma -- 16. Laser therapies for glaucoma: new frontiers -- 17. Modulation of wound healing during and after glaucoma surgery -- 18. Surgical alternative to trabeculectomy -- 19 Modern aqueous shunt implantation: future challenges -- 20. Model systems for experimental studies: retinal ganglion cells in culture -- 21. Rat models for glaucoma research -- 22. Mouse genetic models: an ideal system for understanding glaucomatous neurodegeneration and neuroprotection -- 23. Clinical trials in neuroprotection. 24. Pathogenesis of ganglion "cell death" in glaucoma and neuroprotection: focus on ganglion cell axonal mitochondria -- 25. Astrocytes in glaucomatous optic neuropathy -- 26. Glaucoma as a neuropathy amenable to neuroprotection and immune manipulation -- 27. Oxidative stress and glaucoma: injury in the anterior segment of the eye -- 28 TNF-alpha signaling in glaucomatous neurodegeneration -- 29. Involvement of the Bc12 gene family in the signaling and control of retinal ganglion cell death -- 30. Assessment of neuroprotection in the retina with DARC -- 31. Potential roles of (endo)cannabinoids in the treatment of glaucoma: from intraocular pressure control to neuroprotection -- 32. Glaucoma of the brain: a disease model for the study of transsynaptic neural degeneration -- 33. Changes of central visual receptive fields on experimental glaucoma -- 34. Targeting excitotoxic/free radical signaling pathways for therapeutic intervention in glaucoma -- Stem cells for neuroprotection in glaucoma -- 36. The relationship between neurotrophic factors and CaMKII in the death and survival of retinal ganglion cells -- 37. Evidence of the neuroprotective role of citicoline in glaucoma patients -- 38. Neuroprotection: VEGF, IL-6, and clusterin: the dark side of the moon -- 39. Rational basis for the development of coenzyme Q10 as a neurotherapeutic agent for retinal protection -- 40. 17Beta-estradiol prevents retinal ganglion cell loss induced by the acute rise of intraocular pressure in rat.
- 2010 SpringerPaul N. Schacknow, John R. Samples, editors.Glaucoma in the twenty-first century -- An evidence-based approach to glaucoma care -- Glaucoma risk factors: intraocular pressure -- Glaucoma risk factors: fluctuations in intraocular pressure -- Glaucoma is a 24/7 disease -- Continuous monitoring of intraocular pressure -- Aqueous veins and open angle glaucoma -- Glaucoma risk factors: the cornea -- Glaucoma risk factors: family history-the genetics of glaucoma -- Glaucoma risk factors: ethnicity and glaucoma.
- 2016 SpringerAntonio Ferreras, editor.Standard Automated Perimetry -- Gonioscopy -- Measurement of Intraocular Pressure -- Clinical Applications of Ultrasound Biomicroscopy in Glaucoma -- Retrobulbar Ocular Blood Flow Evaluation in Open Angle Glaucoma -- Optic Nerve Head Assessment and Retinal Nerve Fiber Layer Evaluation -- Confocal Scanning Laser Ophthalmoscopy (HRT) -- Detection of Glaucoma Using Scanning Laser Polarimetry -- Optical Coherence Tomography (OCT) -- Measuring Hemoglobin Levels in the Optic Nerve Head for Glaucoma Management -- Structure & Function Relationship in Glaucoma -- Assessment of Structural Glaucoma Progression.
- 2015 ClinicalKey[editors] Tarek M. Shaarawy, Mark B. Sherwood, Roger A. Hitchings, Jonathan G. Crowston.As the irreversible effects of glaucoma can lead to blindness, there is high demand for early diagnosis and an ongoing need for practitioners to adopt new and evolving medical and surgical treatment options to improve patient outcomes. Glaucoma, Second Edition is the most comprehensive text and online resource in the field delivering expert guidance for the most timely and effective diagnosis and treatment of glaucoma - aimed at specialists, fellows and general ophthalmologists. More than 300 contributors from six continents provide a truly global perspective and explore new approaches in this user friendly reference which has been updated with enhanced images, more spotlights, new videos, and more.
- 2008 ClinicalKeyedited by Teresa C. Chen.Trabeculectomy -- Combined cataract and glaucoma surgery -- Bleb revision -- Ahmed valve surgery -- The Krupin eye valve with disk -- Nonvalved single-plate tube shunt procedures: Baerveldt and Molteno implants -- Double-plate Molteno implants -- The 'taco" tube shunt -- Goniotomy -- Trabeculotomy -- Goniosynechialysis -- Surgical peripheral iridectomy -- Anterior chamber washout -- Posterior sclerectomy for choroidal effusion drainage or prophylaxis -- Argon and Nd: YAG peripheral iridotomy -- Argon laser trabeculoplasty -- Selective laser trabeculoplasty -- Argon laser peripheral iridoplasty -- Transscleral diode cyclophotocoagulation -- Endoscopic cyclophotocoagulation.
- 2012 Kargervolume editors, Paolo Bettin, Peng Tee Khaw.Enhanced trabeculectomy : the Moorfields Safer Surgery System / Khaw, P.T. ... [et al.] -- Deep sclerectomy / Roy, S.; Mermoud, A. -- Glaucoma drainage implant surgery / Aref, A.A.; Gedde, S.J.; Budenz, D.L. -- Postoperative management of penetrating and nonpenetrating external filtering procedures / Bettin, P. -- Ocular surface and external filtration surgery : mutual relationships / Baudouin, C. -- Wound healing and glaucoma surgery : modulating the scarring process with conventional antimetabolites and new molecules / Holló, G. -- Mini-drainage devices : The Ex-PRESS mini-glaucoma device / Rouse, J.M.; Sarkisian Jr, S.R. -- Laser-Assisted Techniques for Penetrating and Nonpenetrating Glaucoma Surgery / Geffen, N.; Assia, E.I. ; Melamed, S. -- Ab externo Schlemm's canal surgery : viscocanalostomy and canaloplasty / Grieshaber, M.C. -- Ab interno Schlemm's canal surgery : trabectome and I-stent / Francis, B.A.; Winarko, J. -- Surgical treatment of angle closure glaucoma / Aquino, M.C. ... [et al.] -- Management of concomitant cataract and glaucoma / Marchini, G.; Ceruti, P.; Vizzari, G. -- Surgical management of pediatric glaucoma / Ou, Y.; Caprioli, J. -- When should we give up filtration surgery : indications, techniques and results of cyclodestruction / Huang, G.; Lin, S.C.
- 2014 SpringerRoberto Sampaolesi, Juan Roberto Sampaolesi, Jorge Zarate.This second volume in a short series on the glaucomas is devoted to the two main types of the disease, open angle glaucoma and angle closure glaucoma. The contents are based on observations and experience gained during the management of more than 40,000 hospital and 7,000 private patients, with follow-up of 10 to 50 years. The book is comprehensive in scope. All aspects of diagnosis are carefully examined, surgical indications and techniques are explained, and the role of medical treatment is evaluated. Importantly, chapters are included on topics that are frequently overlooked in other books but are important to early diagnosis, such as diurnal pressure curve, HRT, and non-conventional perimetry.
- 2016 Ovideditors, Thomas E. Keane, Sam D. Graham, Jr. ; associate editors, Marc Goldstein [and 7 others].Section I. Adrenal, renal, ureter, pelvis / Jerome P. Richie -- section II. Bladder / Stephen J. Savage -- section III. Prostate / Sandip M. Prasad -- section IV. Urethra / Eric S. Rovner -- section V. Testis, epididymis, vas deferens, and seminal vesicles / Marc Goldstein -- section VI. Penis and scrotum / Ramon Virasoro -- section VII. Urinary diversion / Urs E. Studer -- section VIII. Pediatrics / H. Gil Rushton.
- 2010 Ovideditors, Sam D. Graham, Jr., Thomas E. Keane ; consultant editor, James F. Glenn ; associate editors, Charles B. Brendler ... [et al.].Anatomy of the adrenal glands, kidney, ureter, and pelvis -- Partial nephrectomy -- Radical nephrectomy -- Intracaval tumors -- Transplant nephrectomy -- Renovascular disease -- Anatrophic nephrolithotomy -- Renal and retroperitoneal abscesses -- Renal trauma -- Renal allotransplantation -- Ureteral complications following renal transplantation -- Renal autotransplantation -- Anatomy of the bladder -- Simple and partial cystectomy -- Radical cystectomy in men -- Radical cystectomy in women -- Bladder diverticulectomy -- Bladder augmentation -- Management of the distal ureter for nephrourecterectomy -- Vesicovaginal fistula -- Enterovesical and rectourethral fistulas -- Vesical trauma and hemorrhage -- Interstitial cystitis/painful bladder syndrome -- Anatomy of the prostate -- Surgery for benign prostatic hypertrophy -- Prostatic imaging and biopsy -- Pelvic lymphadenectomy -- Open radical retropubic prostatectomy -- Radical perineal prostatectomy -- Brachytherapy for localized prostate cancer -- Anatomy of the urethra -- Female urethral diverticulum -- Reconstruction of the female urethra -- Surgical management of the incompetent bladder outlet in the patient with a neurogenic bladder -- Surgery for urethral stricture disease -- Surgery for urethral trauma including urethral disruption -- Carcinoma of the female urethra -- Carcinoma of the male urethra -- Injectable therapies for incontinence in women -- Pubovaginal fascial slings -- Synthetic midurethral retropubic slings -- The transobturator approach to the midurethral sling -- Abdominal retropubic approaches for female incontinence -- The artificial urinary sphincter -- The male sling for postprostatectomy incontinence: current concepts and controversies -- Sacral neuromodulation -- Surgical treatment of pelvic organ prolapse: anatomy of the pelvic floor -- Vaginal hysterectomy for uterine prolapse -- Cystocele and anterior vaginal prolapse -- Transvaginal repair of apical prolapse -- Posterior vaginal prolapse repair -- Abdominal sacral colpopexy -- Anatomy of the epididymis, vas deferens, and seminal vesicle -- Seminal vesicle and ejaculatory duct surgery -- Vasectomy.; Vasoepididymostomy -- Vasovasostomy -- Microsurgical varicocelectomy -- Testis biopsy and testicular sperm extraction (TESE) -- Epididymal sperm aspiration -- Epididymectomy -- Ejaculation induction procedures: penile vibratory stimulation and electroejaculation -- Anatomy of the testis -- Simple orchiectomy -- Inguinal orchiectomy -- Organ-preserving surgery in testicular tumors -- Retroperitoneal lymphadenectomy -- Torsion of the testicle -- Scrotal trauma and reconstruction -- Anatomy of the penis and scrotum -- Partial and total penectomy in the management of invasive squamous cell carcinoma of the penis -- Inguinal lymphadenectomy for penile carcinoma -- Surgical treatment of Peyronie disease -- Priapism -- Penile prosthesis implantation -- Penile venous surgery -- Microvascular arterial bypass surgery for erectile dysfunction -- Penile trauma -- Penile replantation -- Varicocele: general considerations -- Hydrocele and spermatocele -- Congenital curvature -- Reconstruction of the penis for complications of penile enhancement surgery -- Ileal conduit urinary diversion -- Transverse colonic conduit -- Managing the with patient orthotopic bladder substitution -- Orthotopic urinary diversion using in ileal low-pressure reservoir with an afferent tubular segment -- Ileal neobladder -- The Padua ileal bladder -- The T-pouch ileal neobladder -- Colonic orthotopic bladder substitution -- Continent catheterizable reservoir made from ileum -- Continent catheterizable reservoir made from colon -- Ureterosigmoidostomy: Mainz pouch II -- Palliative urinary diversion -- Neuroblastoma -- Wilms tumor -- Renal fusion and ectopia -- Transureteroureterostomy -- Pyeloplasty -- Megaureter -- Prune belly (triad) syndrome -- Childhood rhabdomyosarcoma -- Vesicoureteral reflux -- Endoscopic treatment of vesicoureteral reflux -- Ureteroceles -- Urachal anomalies and related umbilical disorders -- Vesical neck reconstruction -- Surgery for posterior urethral valves -- Hypospadias -- Complete primary repair for exstrophy -- Bladder exstrophy and epispadias -- Congenital anomalies of the scrotum -- Pediatric cryptorchidism, hydroceles, and hernias -- Laparoscopic management of the undescended testicle -- Pediatric laparoscopic pyeloplasty -- Pediatric laparoscopic nephrectomy and partial nephrectomy.; Urogenital sinus and cloacal anomalies -- Surgery to correct ambiguous genitalia (46XX disorder of sexual development) -- Circumcision -- Augmentation cystoplasty in children -- The mitrofanoff procedure in pediatric urinary tract reconstruction -- Basic principles of laparoscopy: transperitoneal, extraperitoneal, and hand-assisted techniques -- Laparoscopic pelvic and retroperitoneal lymph node dissection -- Laparoscopic nephrectomy and partial nephrectomy -- Laparoscopic nephroureterectomy -- Laparoscopic renal procedures: renal cystectomy, biopsy, and nephropexy -- Laparoscopic ablation of small renal masses -- Donor nephrectomy: laparoscopic techniques -- Laparoscopic and robotically assisted pyeloplasty in adults -- Laparoscopic adrenalectomy -- Laparoscopic and robotic radical prostatectomy -- Laparoscopic management of lymphoceles -- Laparoscopic bladder procedures: radical cystectomy, partial cystectomy, urachal excision, diverticulectomy -- Laparoscopic bladder neck suspension -- Miscellaneous laparoscopic urologic procedures: calculus, varicocele, ureterolysis -- Tissue-engineering strategies for urogenital repair -- Image-guided therapy: current practice and future directions -- Robotic surgery -- Energy sources in urology.
- 2001 ScienceDirectedited by B. Castellano López, Manuel Nieto-Sampedro.Also available: Print – 2001
- 2010 SpringerSwapan K. Ray, editor.
- 2009 SpringerHenry deF. Webster, Karl E. Åström.Gliogenesis -- Astroglia -- Oligodendroglia -- Microglia -- Ependymal cells -- Tanycytes -- Schwann cells.
- 2012 Springeredited by Ryuya Yamanaka.Molecular biology of glioma / Tomotoshi Marumoto and Hideyuki Saya -- Recent surgical management of gliomas / Nader Sanai and Mitchel S. Berger -- Recent medical management of glioblastoma / Derek R. Johnson and Susan M. Chang -- Basic concepts in glioma immunology / Ian F. Parney -- Mechanisms of immune evasion by gliomas / Cleo E. Rolle, Sadhak Sengupta, and Maciej S. Lesniak -- Glioma antigen / Masahiro Toda -- Cytokine therapy / Masasuke Ohno, Atsushi Natsume, and Toshihiko Wakabayashi -- Immunotherapeutic approach with oligodeoxynucleotides containing CpG motifs (CpG ODN) in malignant glioma / Renata Ursu and Antoine F. Carpentier -- Adoptive cell transfer therapy for malignant gliomas / Eiichi Ishikawa ... [et al.] -- Monoclonal antibody therapy for malignant glioma / Kevin S. Chen and Duane A. Mitchell -- Animal models for vaccine therapy / Dong-Sup Chung, Chang-Hyun Kim, and Yong-Kil Hong -- Immunogene therapy / Terry Lichtor and Roberta P. Glick -- Peptide vaccine / Shuichi Izumoto -- Active immunotherapy : oncolytic virus therapy using HSV-1 / Tomoki Todo -- Dendritic cell vaccines / Ryuya Yamanaka and Koji Kajiwara -- Antigen-receptor gene-modified T cells for treatment of glioma / Hiroaki Ikeda and Hiroshi Shiku -- Glioma stem cell research for the development of immunotherapy / Qijin Xu, Xiangpeng Yuan, and John S. Yu.
- 2013 SpringerJolanta Barańska, editor.
- 2016 ScienceDirectedited by Mitchel S. Berger and Michael Weller.Ch. 1. Epidemiology -- Ch. 2. Presenting signs and symptoms in brain tumors -- Ch. 3. Neuroimaging -- Ch. 4. Surgical approaches for the gliomas -- Ch. 5. Histologic classification of gliomas -- Ch. 6. Molecular classification of gliomas -- Ch. 7. Next-generation molecular diagnostics -- Ch. 8. Principles of radiation therapy -- Ch. 9. Principles of pharmacotherapy -- Ch. 10. Principles of immunotherapy -- Ch. 11. Experimental therapies: gene therapies and oncolytic viruses -- Ch. 12. Complications of glioma surgery -- Ch. 13. Complications from radiotherapy -- Ch. 14. Complications from pharmacotherapy -- Ch. 15. Vascular complications in glioma patients -- Ch. 16. Epilepsy and brain tumors -- Ch. 17. Rehabilitation of patients with glioma -- Ch. 18. Psycho-oncology -- Ch. 19. Palliative care at the end-of-life in glioma patients -- Ch. 20. Pilocytic astrocytomas -- Ch. 21. Astrocytic gliomas WHO grades II and III -- Ch. 22. Low-grade and anaplastic oligodendroglioma -- Ch. 23. Glioblastoma -- Ch. 24. Rare glial tumors -- Ch. 25. Ependymoma: a heterogeneous tumor of uncertain origin and limited therapeutic options -- Index.
- 2009 SpringerAndreas von Deimling (ed.).Part I. Gliomas -- Astrocytic tumors / Markus J. Riemenschneider and Guido Reifenberger -- Molecular pathology of oligodendroglial tumors / Christian Hartmann and Andreas von Deimling -- Ependymal tumors / Martin Hasselblatt -- Pediatric gliomas / Stefan Pfister and Olaf Witt -- Hereditary tumor syndromes and gliomas / David Reuss and Andreas von Deimling -- Part II. Management of gliomas -- Surgical management of intracranial gliomas / Matthias Simon and Johannes Schramm -- Radiation therapy / Stephanie E. Combs -- Adjuvant therapy / Wolfgang Wick and Michael Weller -- Other experimental therapies for glioma / Manfred Westphal and Katrin Lamszus -- Neurotoxicity of treatment / Pasquale Calabrese and Uwe Schlegel -- Neuroimaging / R. Klingebiel and G. Bohner -- Part III. Angiogenesis in gliomas / Marcia Machein and Lourdes Sánchez de Miguel -- Gene regulation by methylation / Wolf C. Mueller and Andreas von Deimling -- Brain tumor stem cells / Christian Nern, Daniel Sommerlad, Till Acker and Karl H. Plate.Also available: Print – 2009
- 2007 SpringerKen Takasaki.
- 2007Acknowledgements -- Introduction: about this Guide -- Part 1. Global ageing and urbanization: meeting the challenge of humanity's success -- Part 2. Active ageing: a framework for age-friendly cities -- Part 3. How the Guide was developed -- Part 4. How to use the Guide -- Part 5. Outdoor spaces and buildings -- Part 6. Transportation -- Part 7. Housing -- Part 8. Social Participation -- Part 9. Respect and social inclusion -- Part 10. Civic participation and employment -- Part 11. Communiciation and information -- Part 12. Community support and health services -- Part 13. Wrapping up and moving forward -- References.
- 2015[by Jane Scobie].The Global AgeWatch Index ranks countries according to the social and economic wellbeing of older people.
- 2007/2008Florencia Pauli.
- Global and regional estimates of violence against women : prevalence and health effects of intimate partner violence and non-partner sexual violence2013 WHOwritten by Claudia García-Moreno, Christina Pallitto, Karen Devries, Heidi Stöckl, Charlotte Watts, and Naeemah Abrahams."The report presents the first global systematic review of scientific data on the prevalence of two forms of violence against women: violence by an intimate partner (intimate partner violence) and sexual violence by someone other than a partner (non-partner sexual violence). It shows, for the first time, global and regional estimates of the prevalence of these two forms of violence, using data from around the world. Previous reporting on violence against women has not differentiated between partner and non-partner violence."--Website.
- 2013 SpringerJan Willem van der Laan, Joseph J. DeGeorge, editors.The International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH) is a unique project that brings together the regulatory authorities of Europe, Japan and the US and experts from the pharmaceutical industry in the three regions to discuss scientific and technical aspects of product registration. In Japan, the members are the Ministry of Health, Labour and Welfare (MHLW), and the Japan Pharmaceutical Manufacturers Association (JPMA). In Europe, the members are the EU (Representatives of the European Commission and the European Medicines Agency [EMA]), and the European Federation of Pharmaceutical Industries and Associations (EFPIA). In the United States, the members are the Food and Drug Administration (FDA), and the Pharmaceutical Research and Manufacturers of America (PhRMA). The International Federation of Pharmaceutical Manufacturers Associations (IFPMA) is the secretariat of the ICH. Additional members include Observers from WHO, European Free Trade Association (EFTA), and Canada. The Observers represent non-ICH countries and regions. This volume considers one of ICH's major categories, Safety, covering topics relating to in vitro and in vivo pre-clinical studies (Carcinogenicity Testing, Genotoxicity Testing, etc.). Since the start of the ICH process, many guidelines have been written, but in most cases there is a lack of awareness of the many issues that were addressed during the development of the consensus guidances. Further, just as it is important to understand what the guidances state, it is also important to understand the thoughts, debates, and intent of the experts involved, which are not included in the guidance documents. Why has the guideline been written as it is written, why are some topics ignored, and why have some initial guidance proposals have been deleted. These and other related questions and answers are the contents of this book, written by experts who were directly involved in writing the ICH guidances that drive drug development today.
- 2014editors, Cezmi A. Akdis, Ioana Agache ; editorial board, Pascal Demoly, Peter Hellings, Antonella Muraro, Nikolaos G. Papadopoulos, Ronald van Ree.
- 2011 WHOeditors, Shanthi Mendis, Pekka Puska and Bo Norrving.
- 2008Boerma, J. T.; Fat, Doris Ma; Mathers, Colin D.
- v. 4, 2004 WHOLopez, Alan D.; Murray, Christopher J. L.Also available: Print – v. 1-3, 1996-98.
- 2006 NCBI BookshelfAlan D. Lopez ... [et al.], editors.
- 2012Joshua Asher Weinstein.The adaptive immune system enables individuals to defend against previously un-encountered pathogens by trial and error. It does so by employing receptors, known as antibodies, whose active genetic diversification fine-tunes this defensive response. Tremendous progress has been made in understanding the mechanisms by which antibodies develop and signal activation. However, it was not until a few years ago, with the advent of affordable in-house high-throughput DNA sequencing, and our publication of whole zebrafish antibody repertoires, that any organism's antibody diversity was characterized comprehensively. In this dissertation, we demonstrate the power of this "top-down" approach to illuminate global, system-wide changes of immune receptor repertoires during organism development and immune response. Special attention is given to applying these measurements to build predictive dynamical models that elucidate the interplay between antibody-sequences and the B-cells that produce them. While we use zebrafish liberally as a model organism for these purposes, cross-species comparisons establish far more general principles of repertoire organization. We go further to evaluate the efficacy of high-throughput immune receptor sequencing to advance clinical goals by inferring which vaccines were received by human patients based on antibody-sequences obtained from whole blood afterward. Finally, we demonstrate the usefulness of single B-cell measurements to correlate antibody mutations to gene expression, thereby providing insight into how these variables co-vary system-wide. This work serves to illustrate the potential of global characterizations of antibody repertoires for providing newer and clearer pictures of immune dynamics in general.
- 2014 SpringerKent E. Pinkerton, William N. Rom, editors.Pulmonary physicians and scientists currently have minimal capacity to respond to climate change and its impacts on health. The extent to which climate change influences the prevalence and incidence of respiratory morbidity remains largely undefined. However, evidence is increasing that climate change does drive respiratory disease onset and exacerbation as a result of increased ambient and indoor air pollution, desertification, heat stress, wildfires, and the geographic and temporal spread of pollens, molds and infectious agents. Preliminary research has revealed climate change to have potentially direct and indirect adverse impacts on respiratory health. Published studies have linked climate change to increases in respiratory disease, including the following: changing pollen releases impacting asthma and allergic rhinitis, heat waves causing critical care-related diseases, climate driven air pollution increases, exacerbating asthma and COPD, desertification increasing particulate matter (PM) exposures, and climate related changes in food and water security impacting infectious respiratory disease through malnutrition (pneumonia, upper respiratory infections). High level ozone and ozone exposure has been linked to idiopathic pulmonary fibrosis, lung cancer, and acute lower respiratory infection. Global Climate Change and Public Health is an important new volume based on the research, findings, and discussions of US and international experts on respiratory health and climate change. This volume addresses issues of major importance to respiratory health and fills a major gap in the current literature.
- 2011 ScienceDirectRichard Chin, Menghis Bairu [editors].
- 2014 ScienceDirectedited by Menghis Bairu, Michael Weiner.
- 2012 ScienceDirectedited by Menghis Bairu and Richard Chin.
- v. 1-3, 1944-54.by James Stevens Simmons ... [et al.].v. 1. pt. 1. India and the Far East. pt. 2. The Pacific area.
- 2012George Dehner.Know your enemy -- The Murky past of influenza -- Misidentifications and false starts -- The 1920s to the 1980s -- Renewed fears of flu -- Yet another surprise.
- 2013 SpringerDavid V. McQueen, editor.Section I. Theoretical and methodological issues -- High-risk versus population prevention strategies for NCDs: Geoffrey Rose revisited in the twenty-first century -- Current and future theoretical foundations for NCDs and health promotion -- The nature of causality: beyond traditional evidence -- Surveillance for NCDs and health promotion: an issue of theory and method -- Section II. Lenses for understanding NCDs -- Learning from the social sciences in chronic diseases health promotion: structure, agency and distributive justice -- Contextual factors in health and illness -- The social determinants of non-communicable diseases: a political perspective -- Risk factors: tobacco -- Physical inactivity and health promotion: evidence and challenges -- NGOs addressing NCDs through a health promotion lens -- Health literacy as a lens for understanding non-communicable diseases and health promotion -- From healthy public policy to intersectoral action and health-in-all policies -- Section III. Approaches to NCDs -- Population health intervention research: a fundamental science for NCD prevention -- Planning and management of cross-sectoral programs: strategies to address NCDs -- The public policy approach: governments, institutions, welfare states and social justice -- Accelerating action on NCDs: Understanding and applying a social determinants of health framework for changes -- Cardiovascular health, risk, and disease: primordial and remedial strategies -- Advocacy strategies to address NCDs: actions to increase the profile of physical activity -- Advocacy strategies to address NCDs: tobacco control -- Evidence synthesis to inform NCD prevention and health promotion -- Using evidence to inform NCD prevention and heal promotion -- The health promotion argument: NCDs and public health -- Public health, NDCs, health promotion, and business partnering: benefits, concerns, remedies, and moving towards creative partnering -- Section IV. Institutions and organizations -- Framing international trade and chronic disease -- Addressing NCDs through multilateral engagement at the United Nations: The role of WHO -- Governance, policy, and institutions -- NCDs and civil society: a history and a roadmap -- Developing health promotion workforce capacity for addressing non-communicable diseases globally -- Health promotion for NCDs in and by hospitals: a health promoting hospital perspective.
- 2013Merrill Singer, Pamela I. Erickson.
- 2013 SpringerIlona Kickbusch, Graham Lister, Michaela Told, Nick Drager, editors.The world's problems are indeed world problems: social and environmental crises, global trade and politics, and major epidemics are making public health a pressing global concern. From this constantly changing scenario, global health diplomacy has evolved, at the intersection of public health, international relations, law, economics, and management--a new discipline with transformative potential. Global Health Diplomacy situates this concept firmly within the human rights dialogue and provides a solid framework for understanding global health issues and their negotiation. This up-to-the-minute guide sets out defining principles and the current agenda of the field, and examines key relationships such as between trade and health diplomacy, and between global health and environmental issues. The processes of global governance are detailed as the UN, WHO, and other multinational actors work to address health inequalities among the world's peoples. And to ensure maximum usefulness, the text includes plentiful examples, discussion questions, reading lists, and a glossary. Featured topics include: The legal basis of global health agreements and negotiations.Global public goods as a foundation for global health diplomacy.Global health: a human security perspective.Health issues and foreign policy at the UN.National strategies for global health.South-south cooperation and other new models of development. A volume of immediate utility with a potent vision for the future, Global Health Diplomacy is an essential text for public health experts and diplomats as well as schools of public health and international affairs.
- 2014Lawrence O. Gostin.Global health justice : towards a transformative agenda for health equity -- Globalized health hazards : the need for collective global action -- Global health law in the broader currents of global governance for health -- Fulfilling the promise of the World Health Organization -- Old and new institutions : from the World Bank to the Global Fund, GAVI Alliance, and Gates Foundation -- The international health regulations : responding to public health emergencies of international concern -- The Framework Convention on Tobacco Control : the global response to tobacco -- Health and human rights : human dignity, global justice, and personal security -- Global health, international trade, and intellectual property : toward a fair deal for the global south -- "Getting to zero" : scientific innovation, social mobilization, and human rights in the AIDS pandemic -- The international migration of health workers : a troubling example of global injustice -- Pandemic influenza: a case study on global health security -- The "silent" pandemic of non-communicable diseases -- Imagining global health with justice.
- 2010David William Hutton.Hepatitis B (HBV) is a vaccine-preventable viral disease that, if untreated, can lead to death from liver disease in 25 percent of patients. Infection with HBV is a major global public health problem, particularly in Asian populations. In an era of limited healthcare budgets, mathematical models can be useful tools to identify cost-effective programs and to support policymakers in making informed decisions. This dissertation describes research on public health policies related to screening, vaccination, and treatment for HBV. It also describe contributions to the theoretical literature on when to stop catch-up vaccination for chronic infectious diseases. In the United States as many as 10% of Asian and Pacific Islander adults are chronically infected with HBV, and up to two thirds are unaware that they are infected. Using Markov models of infection, treatment and disease, I find that screening programs for HBV among Asian and Pacific Islander adults are likely to be cost effective and have clinically significant benefits from identifying chronically infected persons for medical management. Liver disease associated with childhood-acquired HBV is a leading cause of death among adults in China. Approximately 20% of children under age 5 years and 40% of children aged 5 to 19 years remain unprotected from HBV. Using a Markov model of infection and disease progression I find that HBV catch-up vaccination for children and adolescents in China would improve the health of the population and save costs over the long term. Although the 20th century has seen incredible development of safe and effective vaccines, many people remain susceptible to vaccine-preventable diseases. "Catch-up vaccination" for age groups beyond infancy can be an attractive and effective means of immunizing people who were missed earlier. However, as vaccination rates increase, catch-up vaccination may become less attractive. This chapter addresses the question of when to discontinue catch-up vaccination programs as immunization rates increase. I use a cost-effectiveness framework: I consider the cost per quality-adjusted life year gained of catch-up vaccination efforts, as a function of immunization rates over time and consequent disease prevalence and incidence. I illustrate the results with the example of HBV catch-up vaccination in China. I contrast results from a dynamic modeling approach with an approach that ignores the impact of vaccination on disease incidence.
- 2013Deanna Kerrigan, Andrea Wirtz, Stefan Baral, Michele Decker, Laura Murray, Tonia Poteat, Carel Pretorius, Susan Sherman, Mike Sweat, Iris Semini, N'Della N'Jie, Anderson Stanciole, Jenny Butler, Sutayut Osornprasop, Robert Oelrichs, and Chris Beyrer.This volume presents an integrated epidemiologic, social, and economic analysis of the global epidemics of HIV among sex workers in low- and middle-income countries. The book provides a comprehensive review and synthesis of the available public health and social science data to characterize the nature, scope, and complexities of these epidemics. A community empowerment-based approach to HIV prevention, treatment, and care is outlined and demonstrated to be cost-effective across multiple settings, with a significant projected impact on HIV incidence among sex workers and transmission dynamics overall. The Global HIV Epidemics among Sex Workers seeks to assist governments, public health implementing agencies, donors, and sex worker communities to better understand and respond to the epidemics among a population facing heightened social and structural vulnerabilities to HIV. The book combines a systematic review of the global epidemiology of HIV among sex workers and in-depth case studies of the epidemiology, policy and programmatic responses and surrounding social contexts for HIV prevention, care and treatment in eight countries. The authors employ mathematical modeling and cost-effectiveness analysis to assess the potential country-level impact of a community empowerment-based approach to HIV prevention, treatment, and care among sex workers when taken to scale in four countries representing diverse sociopolitical contexts and HIV epidemics: Brazil, Kenya, Thailand, and Ukraine. In each setting, greater investment in prevention, treatment, and care for sex workers is shown to significantly reduce HIV. Together these findings underline the urgency of further global investment in comprehensive, human rights-based responses to HIV among sex workers.
- 2013Martin Prince, Maëlenn Guerchet, and Matthew Prina.Although high income countries, including the G8, have borne the brunt of the dementia epidemic, this is a global phenomenon. Most people with dementia live in low and middle income countries, and most of the dramatic increases in numbers affected, through to 2050, will occur in those regions. In a spirit of international cooperation and solidarity we urge the G8 governments to sponsor intergovernmental action to make dementia a global priority. Crucially, this must include opening up access to diagnosis and current evidence-based treatment and care. All countries worldwide are failing in this basic objective. Action to address this problem should be balanced, as a priority, with research to improve treatment options and quality of care.
- 2008 SpringerBradly J. Condon, Tapen Sinha.
- The Global Library of Women's Medicine is a unique web library incorporating a vast range of detailed clinical information across women's medicine. It consists of 442 main chapters and 53 supplementary chapters, supported by over 40,000 references, which will be kept permanently up-to-date. The chapters have been written by more than 650 specialists and will reflect some of the very best worldwide opinion.
- 2013T. Randolph Beard, David L. Kaserman, and Rigmar Osterkamp ; with a foreword by Friedrich Breyer.The evolution of organ transplantation and procurement policy -- Consequences of the current policy -- Social costs and benefits of transplants -- Economic and political causes of the shortage of organs -- Reforms short of open donor compensation -- An assessment of the moral basis of alternative organ donation rules -- Compensation for organ donation and a proposal for a public monopsony for organ acquisition.
- 2014 SpringerR. Gosselin, D. Spiegel, M. Foltz (eds.).Global Orthopedics: Caring for Musculoskeletal Conditions and Injuries in Austere Settings was conceived and written to be a unique reference for surgeons working in resource-limited environments. The first sections provide historical background, global public health perspectives of orthopedics, the role of culture, and a broad discussion of non-surgical and non-orthopedic clinical topics that are rarely encountered in high-resource settings but that affect orthopedic care. Adult and pediatric trauma are presented in an anatomical format for easy reference, with a focus on the natural history and the best treatment methods within existing limitations. The chapters on musculoskeletal infections provide a wealth of knowledge about these common debilitating conditions that is unavailable in any other single modern text. The non-infectious pediatric conditions section has been written for the non-specialist to handle selected developmental and early childhood orthopedic problems commonly seen in low-resource settings. Detailed chapters on reconstruction surgery, tumor management, amputations, and the orthopedic needs in the face of conflicts and natural disasters round out the text.
- 2011 ScienceDirectedited by Debasis Bagchi.Chapter 1. Pediatric Obesity: A Pediatrician's Viewpoint / Allison Collins, Rebecka Peebles -- Chapter 2. Salient Features on Child Obesity from the Viewpoint of a Nutritionist / Bernard Waysfeld, Dominique Adele Cassuto -- Chapter 3. Developmental Trajectories of Weight Status in Childhood and Adolescence / Samar Hejazi, V. Susan Dahinten, Pamela A. Ratner, Sheila K. Marshall -- Chapter 4. The Measurement and Epidemiology of Child Obesity / David S. Freedman, Cynthia L. Ogden, Sarah E. Cusick -- Chapter 5. Good-Enough Parenting, Self-Regulation, and the Management of Weight-Related Problems / Moria Golan -- Chapter 6. Nursing Perspective on Childhood Obesity / Cynthia Yensel, Carrie Tolman -- Chapter 7. Contemporary Racial/Ethnic and Socioeconomic Patterns in U.S. Childhood Obesity / Gopal K. Singh, Michael D. Kogan -- Chapter 8. Prediabetes among Obese Youth / Orit Pinhas-Hamiel, Phil Zeitler -- Chapter 9. Prediabetes and Type 2 Diabetes: An Emerging Epidemic among Obese Youth / Kathryn Love-Osborne -- Chapter 10. Prevalence of the Metabolic Syndrome in U.S. Youth / Sarah E. Messiah, Kristopher L. Arheart, Steven E. Lipshultz, Tracie L. Miller -- Chapter 11. Emerging Pathways to Child Obesity Starts from the Mother's Womb: A Prospective View / Ashik Mosaddik -- Chapter 12. The Social, Cultural and Familial Contexts Contributing to Childhood Obesity / Cathy Banwell, Helen Kinmonth, Jane Dixon -- Chapter 13. Cardiovascular Risk Clustering in Obese Children / Ram Weiss -- Chapter 14. A Link between Maternal and Childhood Obesity / Siân Robinson -- Chapter 15. Is Prenatal Exposure to Maternal Obesity Linked to Child Mental Health? / Alina Rodriguez -- Chapter 16. Sleep and Obesity in Children and Adolescents / Amy Darukhanavala, Silvana Pannain -- Chapter 17. Cellular Remodeling during the Growth of the Adipose Tissue / Coralie Sengenès, Virginie Bourlier, Jean Galitzky, Alexia Zakaroff-Girard, Max Lafontan, Anne Bouloumié -- Chapter 18. Children Obesity, Glucose Tolerance, Ghrelin, and Prader-Willi Syndrome / Simonetta Bellone, Arianna Busti, Sara Belcastro, Gianluca Aimaretti, Gianni Bona, Flavia Prodam -- Chapter 19. Insulin Resistance and Glucose Metabolism in Childhood Obesity / Subhashini Yaturu, Sushil K. Jain -- Chapter 20. Insulin Resistance in Pediatric Obesity: Physiological Effects and Possible Diet Treatment / Ulf Holmbäck -- Chapter 21. Role of Fatty Liver Disease in Childhood Obesity / Valerio Nobili, Anna Alisi, Melania Manco -- Chapter 22. An Overview of Psychosocial Symptoms in Obese Children / Lisa Y. Gibson -- Chapter 23. Childhood Obesity: Depression, Anxiety and Recommended Therapeutic Strategies / Dana L. Rofey, Jessica J. Black, Jennifer E. Phillips, Ronette Blake, KayLoni Olson -- Chapter 24. The Emotional Impact of Obesity on Children / Robert E. Cornette -- Chapter 25. Psychiatric Illness, Psychotropic Medication, and Childhood Obesity / Lawrence Maayan, Leslie Citrome -- Chapter 26. Childhood Obesity: Public Health Impact and Policy Responses / Rogan Kersh, Brian Elbel -- Chapter 27. Childhood Obesity and Juvenile Diabetes / Mikael Knip -- Chapter 28. Bone Health in Obesity and the Cross Talk between Fat and Bone / Sowmya Krishnan, Venkataraman Kalyanaraman -- Chapter 29. A Community-Level Perspective for Childhood Obesity Prevention / Christina Economos, Erin Hennessy -- Chapter 30. School-Based Obesity-Prevention Programs / Genevieve Fridlund Dunton, Casey P. Durand, Nathaniel R. Riggs, Mary Ann Pentz -- Chapter 31. School-Based Obesity Prevention Interventions Show Promising Improvements in the Health and Academic Achievements among Ethnically Diverse Young Children / Danielle Hollar, Sarah E. Messiah, Gabriela Lopez-Mitnik, T. Lucas Hollar, Michelle Lombardo -- Chapter 32. School and Community-Based Physical Education and Healthy Active Living Programs: Holistic Practices in Hong Kong, Singapore, and the United States / Ming-Kai Chin, Christopher R. Edginton, Mei-Sin Tang, Kia-Wang Phua, Jing-Zhen Yang -- Chapter 33. Schools as “Laboratories” for Obesity Prevention: Proven Effective Models / Michelle Lombardo, Danielle Hollar, T. Lucas Hollar, Karen McNamara -- Chapter 34. Fitness and Fatness in Childhood Obesity: Implications for Physical Activity / Sarah P. Shultz, Benedicte Deforche, Nuala M. Byrne, Andrew P. Hills -- Chapter 35. Pharmacotherapy in Childhood Obesity / Amélio F. Godoy-Matos, Erika Paniago Guedes, Luciana Lopes de Souza, Mariana Farage -- Chapter 36. Beverage Interventions to Prevent Child Obesity / Rebecca Muckelbauer, Mathilde Kersting, Jacqueline Müller-Nordhorn -- Chapter 37. Psychotherapy as an Intervention for Child Obesity / Carl-Erik Flodmark -- Chapter 38. Childhood Obesity: Psychological Correlates and Recommended Therapeutic Strategies / Jennifer E. Phillips, Ethan E. Hull, Dana L. Rofey -- Chapter 39. Dietary Supplements in the Prevention and Treatment of Childhood Obesity / Robert I-San Lin -- Chapter 40. The Role of Arginine for Treating Obese Youth / Catherine J. McNeal, Guoyao Wu, Susie Vasquez, Don P. Wilson, M. Carey Satterfield, Jason R. McKnight, Hussain S. Malbari, Mujtaba Rahman -- Chapter 41. Prevention of Childhood Obesity with Use of Natural Products / Jin-Taek Hwang, Dae Young Kwon, Joohun Ha -- Chapter 42. The Role of United States Law to Prevent and Control Childhood Obesity / Jennifer L. Pomeranz -- Chapter 43. Childhood Obesity as an Amplifier of Societal Inequality in the United States / Stanley J. Ulijaszek -- Chapter 44. Childhood Obesity, Food Choice and Market Influence / Jane Kolodinsky, Amanda Goldstein, Erin Roche -- Chapter 45. The Role of Media in Childhood Obesity / Amy B. Jordan, Ariel Chernin -- Chapter 46. Evaluation and Management of Childhood Obesity in Primary Care Settings / Goutham Rao -- Chapter 47. The Future Directions and Clinical Management of Childhood Obesity / Clodagh S. O'Gorman, Jonathan Cauchi, Jill K. Hamilton, Denis Daneman.
- 2007 Springeredited by David V. McQueen and Catherine M. Jones.Global perspectives on health promotion and effectiveness: an introduction / David V. McQueen and Catherine M. Jones -- The Global Programme on Health Promotion Effectiveness (GPHPE): a global process for assessing health promotion effectiveness with regional diversity / Catherine M. Jones ... [et al.] -- The IUHPE blueprint for direct and sustained dialogue in partnership initiatives / Catherine M. Jones and Maurice B. Mittelmark -- The Global Programme on Health Promotion Effectiveness: a case study of global partnership functioning / J. Hope Corbin and Maurice B. Mittelmark -- Policies for health: the effectiveness of their development, adoption, and implementation / Evelyne de Leeuw -- Strengthening the evidence base for mental health promotion / Margaret M. Barry ... [et al.] -- Effectiveness and challenges for promoting physical activity globally / Trevor Shilton ... [et al.] -- School health promotion: achievements, challenges, and priorities / Lawrence St. Leger ... [et al.] -- Health promotion to prevent obesity: evidence and policy needs / Tim Lobstein and Boyd Swinburn -- Effective health promotion against tobacco use / Karen Slama ... [et al.] -- Effectiveness of health promotion in preventing alcohol related harm / Peter Howat ... [et al.] -- Globalization and health promotion: the evidence challenge / Ronald Labonte -- Urbanization and health promotion: challenges and opportunities / Andrea Neiman and Mary Hall -- Community interventions on social determinants of health: focusing the evidence / Marilyn Metzler ... [et al.] -- Strengthening peace-building through health promotion: development of a framework / Anne W. Bunde-Birouste and Jan E. Ritchie -- The role of governance in health promotion effectiveness / Marilyn Wise -- Evidence and theory: continuing debates on evidence and effectiveness / David V. McQueen -- Measurement and effectiveness: methodological considerations, issues, and possible solutions / Stefano Campostrini -- Healthy settings: building evidence for the effectiveness of whole system health promotion--challenges and future directions / Mark Dooris ... [et al.] -- Feasibility for health promotion under various decision-making contexts / Ligia de Salazar -- Evaluating equity in health promotion / Louise Potvin, Pascale Mantoura, and Valéry Ridde -- Evaluation of empowerment and effectiveness: universal concepts? / Valéry Ridde, Treena Delormier, and Ghislaine Goudreau -- Enhancing the effectiveness and quality of health promotion: perspectives of the International Union for Health Promotion and Education / Maurice B. Mittelmark ... [et al.] -- Annex: Global Programme on Health Promotion Effectiveness: description and list of partners.
- 2013 SpringerIchiro Kawachi, Soshi Takao, S.V. Subramanian, editors.The idea of social capital emerged in the social science disciplines to explain puzzling phenomena such as why some communities fare better in crisis than others. As the field matures, it has been adapted to wide-ranging issues such as population health. This book presents the major research issues as well as nuanced theoretical discussion in keeping with an evolving field in Europe, Asia, and the U.S. Background chapters analyze how social capital manifests in neighborhoods, workplaces, and schools, and its relationship to health. The second half offers guidelines for improving population health at the social capital level, and examples of interventions, such as microfinance programs, in which enhanced social capital and health benefits are a significant by-product. And a number of contributors debate the problems of defining the concept and using the term at all.
- 2012 WHONavigating the GPIRM -- Acronyms and abbreviations -- Contributors -- Foreword -- Executive summary -- Part 1. The threat of insecticide resistance -- 1.1 Malaria vector control today -- 1.2 Status of insecticide resistance -- 1.3 Potential effect of resistance on the burden of malaria -- 1.4 Available strategies for managing resistance -- Part 2. Collective strategy against insecticide resistance -- 2.1 Overall malaria community strategy -- 2.2 Country activities -- 2.3 Research agenda -- 2.4 enabling mechanisms -- 2.5 Financial cost -- Part 3. Technical recommendations for countries -- 3.1 Geographical areas with unknown levels of resistance -- 3.2 Geographical areas in which indoor residual spraying is the main form of vector control -- 3.3 Geographical areas in which LLINs are the main form of vector control -- 3.4 Geographical areas in which LLINs and IRs are already used in combination -- 3.5 Choosing alternative insecticides -- Part 4. Near-term action plan -- 4.1 Role of each stakeholder group -- 4.2 Action plan -- References -- Annex 1 Past use of malaria vector control tools -- Annex 2 Long-lasting insecticidal nets, indoor residual spraying and other vector control interventions -- Annex 3 History of insecticide resistance in malaria vectors -- Annex 4 Challenges in measuring the impact of insecticide resistance on the effectiveness of vector control -- Annex 5 example of 'tipping-point' in resistant Aedes mosquitoes -- Annex 6 selection pressure: role of public health, agriculture and other factors -- Annex 7 Implications of discriminating doses of insecticide on detection of resistance -- Annex 8 Main hypotheses used to model the impact of insecticide resistance on malaria burden -- Annex 9 use of insecticide resistance management strategies (rotations, combinations, mosaics and mixtures) -- Annex 10 Genetic research agenda -- Annex 11 Financial modelling -- Annex 12 Definitions.
- 2012 WHO
- 2016 WHOWorld Health Organanization.Preface -- Acknowledgements -- Executive summary -- Background -- Part 1. Global burden of diabetes -- 1.1. Mortality from high blood glucose, including diabetes -- 1.2. Prevalence of diabetes and associated risk factors -- 1.3 Burden and trends in the complications of diabetes -- 1.4. Summary -- Part 2. Preventing diabetes -- 2.1. Population-based prevention -- 2.2. Preventing diabetes in people at high risk -- 2.3. Summary -- Part 3. Managing diabetes -- 3.1. Diagnosis and early detection -- 3.2. Management of diabetes--core components -- 3.3. Integrated management of diabetes and other chronic health conditions -- 3.4. Access to essential medicines and basic technologies -- 3.5. Summary -- Part 4. National capacity for prevention and control of diabetes: a snapshot -- 4.1. National policies and plans for diabetes -- 4.2. National guidelines and protocols -- 4.3. Availability of essential medicines and technologies -- 4.4. Surveillance and monitoring -- 4.5. Summary -- Conclusions and recommendations -- Annexes -- Annex A. Current WHO recommendations for the diagnostic criteria for diabetes and intermediate hyperglycaemia -- Annex B. Methods for estimating diabetes prevalence, overweight and obesity.Also available: Print – 2016
- 2014 WHOThe WHO Global report on drowning: preventing a leading killer highlights that 372,000 people drown worldwide each year. Drowning is among the ten leading causes of death for children and young people in every region of the world. The report sets out the evidence showing a range of effective drowning prevention strategies, and makes a number of recommendations for concrete measures to be taken by national and local governments. With the release of this report, WHO aims to galvanize attention and action to this issue by highlighting how collaboration across sectors can save lives.--Publisher description.
- [Laura Thomas].Key Terms in Palliative Care and Pain Treatment -- Summary -- I. Background: Palliative Care and Pain Treatment -- The Need for Palliative Care and Pain Treatment -- The Consequences of Untreated Pain and Lack of Palliative Care -- Impact of Palliative Care and Pain Management -- The Palliative Care and Pain Treatment Gap -- Barriers to Palliative Care and Pain Treatment -- II. Survey Findings: Global Overview of Barriers to Pain Treatment -- Availability of Policies that Promote Palliative Care and Pain Treatment -- Training for Healthcare Workers -- Drug Availability -- Supply and Distribution System for Opioid Analgesics -- Drug Regulations -- Cost of Opioid Medications -- Best Practices: Addressing Barriers to Pain Treatment and Palliative Care through Comprehensive Reform -- Africa Map -- III. Sub-Saharan Africa -- Regional Overview -- Drug Availability -- Drug Regulations -- Best Practice and Reform Efforts: Uganda -- The Americas Map -- IV. The Americas -- Regional Overview -- Drug Availability -- Best Practice and Reform Efforts: Colombia -- The Middle East and North Africa Map -- V. The Middle East and North Africa -- Regional Overview -- Drug Availability -- Developing Palliative Care: Jordan -- Europe Map -- VI. Europe -- Regional Overview -- Drug Availability -- Best Practice and Reform Efforts: Romania -- Asia Map -- VII. Asia -- Regional Overview -- Drug Availability -- Developing Palliative Care: Vietnam -- VIII. International Human Rights Obligations and Pain Treatment -- Health as a Human Right -- Pain Treatment and the Right to the Highest Attainable Standard of Health -- Pain Treatment and the Right to Be Free from Cruel, Inhuman, and Degrading Treatment -- IX. Recommendations -- To Governments around the World -- General -- Ensuring an Effective Supply System -- Developing and Enacting Pain Management and Palliative Care Policies -- Ensuring Instruction for Healthcare Workers -- Reforming Drug Regulations -- Ensuring Affordability of Medications -- To Global Drug Policy Makers -- To the WHA, WHO, UNAIDS, and the Donor Community -- To the Global Human Rights Community -- X. Methodology -- Acknowledgements -- Appendix 1. List of Survey Participants -- Appendix 2. Survey Questions -- Appendix 3. Table of Calculations Used to Produce Maps.
- 2011 WHO"This publication presents a comprehensive perspective on the worldwide, regional and country consumption of alcohol, patterns of drinking, health consequences and policy responses in member states. It represents a continuing effort by WHO to support member states with global information in their efforts to reduce the harmful use of alcohol and its health and social consequences"--Publisher's description.
- 2014 WHOThe Global status report on alcohol and health 2014 presents a comprehensive perspective on the global, regional and country consumption of alcohol, patterns of drinking, health consequences and policy responses in Member States. It represents a continuing effort by the World Health Organization (WHO) to support Member States in collecting information in order to assist them in their efforts to reduce the harmful use of alcohol, and its health and social consequences. The report was launched in Geneva on Monday 12 May 2014 during the second meeting of the global network of WHO national counterparts for implementation of the global strategy to reduce the harmful use of alcohol.--Publisher's description.
- 2014 WHOThis global status report on prevention and control of NCDs (2014), is framed around the nine voluntary global targets. The report provides data on the current situation, identifying bottlenecks as well as opportunities and priority actions for attaining the targets. The 2010 baseline estimates on NCD mortality and risk factors are provided so that countries can report on progress, starting in 2015. In addition, the report also provides the latest available estimates on NCD mortality (2012) and risk factors, 2010-2012. All ministries of health need to set national NCD targets and lead the development and implementation of policies and interventions to attain them. There is no single pathway to attain NCD targets that fits all countries, as they are at different points in their progress in the prevention and control of NCDs and at different levels of socioeconomic development. However all countries can benefit from the comprehensive response to attaining the voluntary global targets presented in this report.--Publisher description.
- 2011 WHO"This report sets out the statistics, evidence and experiences needed to launch a more forceful response to the growing threat posed by noncommunicable diseases. While advice and recommendations are universally relevant, the report gives particular attention to conditions in low- and middle-income countries, which now bear nearly 80% of the burden from diseases like cardiovascular disease, diabetes, cancer and chronic respiratory diseases. The health consequences of the worldwide epidemic of obesity are also addressed. The report takes an analytical approach, using global, regional and country-specific data to document the magnitude of the problem, project future trends, and assess the factors contributing to these trends. As noted, the epidemic of these diseases is being driven by forces now touching every region of the world: demographic aging, rapid unplanned urbanization, and the globalization of unhealthy lifestyles"--Publisher's description.
- 2015 WHO
- 2013 WHOThis report provides legislation data last updated in 2011 and fatality data updated for 2010.
- 2009 WHODepartment of Violence & Injury Prevention & Disability, World Health Organization."Over 1.2 million people die each year on the world' roads, and between 20 and 50 million suffer non-fatal injuries. In most regions of the world this epidemic of road traffic injuries is still increasing. In the past five years most countries have endorsed the recommendations of the World report on road traffic injury prevention which give guidance on how countries can implement a comprehensive approach to improving road safety and reducing the death toll on their roads. To date, however, there has been no global assessment of road safety that indicates the extent to which this approach is being implemented. This Global status report on road safety is the first broad assessment of the status of road safety in 178 countries, using data drawn from a standardized survey conducted in 2008. The results provide a benchmark that countries can use to assess their road safety position relative to other countries, while internationally the data presented can collectively be considered as a global "aseline"against which progress over time can be measured. " - p. [v11]Also available: Print – 2009
- 2014 WHOWorld Health Organization ; UNODC, United Nations Office on Drugs and Crime ; UNDP, United Nations Development Programme ; [Alexander Butchart and Christopher Mikton coordinated and wrote the report].The Global status report on violence prevention 2014, which reflects data from 133 countries, is the first report of its kind to assess national efforts to address interpersonal violence, namely child maltreatment, youth violence, intimate partner and sexual violence, and elder abuse. Jointly published by WHO, the United Nations Development Programme, and the United Nations Office on Drugs and Crime, the report reviews the current status of violence prevention efforts in countries, and calls for a scaling up of violence prevention programmes; stronger legislation and enforcement of laws relevant for violence prevention; and enhanced services for victims of violence.--Publisher description
- 2010 WHOThe global strategy to reduce the harmful use of alcohol. Setting the scene -- Challenges and opportunities -- Aims and opportunities -- Guiding principles -- National policies and measures -- Policy options and interventions -- Global action : key roles and components -- Implementing the strategy -- Resolution of the sixty-third World Health Assembly (May 2010) WHA63.13 Global Strategy to Reduce the Harmful Use of Alcohol.
- Global surveillance, prevention and control of chronic respiratory diseases : a comprehensive approach.2007Bousquet, Jean; Khaltaev, Nikolai.
- 2014 WHOSupplement WHOWorld Health Organization."This is the nineteenth global report on tuberculosis (TB) published by WHO in a series that started in 1997. It provides a comprehensive and up-to-date assessment of the TB epidemic and progress in implementing and financing TB prevention care and control at global regional and country levels using data reported by over 200 countries that account for over 99% of the world's TB cases. The report is accompanied by a special supplement that marks the 20th anniversary of the establishment of the Global Project on Anti-TB Drug Resistance Surveillance. The supplement highlights the latest status of knowledge about the epidemic of multidrug-resistant TB (MDR-TB) and the programmatic response."--Ebook Library.
- 2013 WHOWorld Health Organization.ch. 1. Introduction -- ch. 2. The burden of disease caused by TB -- ch. 3. TB case notifications and treatment outcomes -- ch. 4. Drug-resistant TB -- ch. 5. Diagnostics and laboratory strengthening -- ch. 6. Addressing the co-epidemics of TB and HIV -- ch. 7. Financing -- ch. 8. Research and development.
- 2015 WHO
- 2012 WHOWorld Health Organization."The World Health Organization (WHO) Global Tuberculosis Report 2012 provides the latest information and analysis about the tuberculosis (TB) epidemic and progress in TB care and control at global, regional and country levels. It is based primarily on data reported by WHO's Member States in annual rounds of global TB data collection. In 2012, 182 Member States and a total of 204 countries and territories that collectively have more than 99% of the world's TB cases reported data." --Executive summary, p. 1.
- 2006 Springeredited by Belinda Bennett and George F. Tomossy.
- 2013edited by I. Glenn Cohen."Gives an integrated approach to interdisciplinary problems that spans fields including law and medicine. -- Medical tourism and telemedicine are growing rapidly in the last decade and this book helps readers to understand the implications of this development. -- Aids readers in understanding the impact of Obamacare on the globalization of health care." -- [Publisher-supplied data]
- 2014 SpringerMirto Foletto, Raul J. Rosenthal, editors ; foreword by Nicola Scopinaro.The increasing prevalence of morbid obesity has led the World Health Organization to coin the descriptive term "globesity" to reflect the worldwide nature of the problem. Providing health care to these patients, especially when surgery is required, can be extremely challenging owing to the specific needs in respect of logistics, facilities, and professional expertise. Appropriate care has too often been unachievable and unaffordable outside of established bariatric centers, but such centers themselves usually have insufficient capacity and resources to cope with growing demand. This book aims to provide guidance and helpful tips and tricks on how to deal with obese patients within a general surgery setting. Epidemiology, organizational and logistical aspects, nursing issues, patient assessment, anesthesiology, and surgical practicalities are expertly covered in the opening chapters. Techniques of relevance to the general surgeon are described according to anatomic region, covering the head and neck; cardiothoracic and vascular system; upper and lower GI tract; pancreas, liver and adrenal glands; urinary tract and kidneys; the reproductive system; and the abdominal wall. Results achieved by bariatric surgery worldwide are reviewed, and the book closes with a chapter devoted to plastic and reconstructive surgery. The Globesity Challenge to General Surgery highlights a need for global rethinking on public health as regards resource allocation and patterns and standards of care, improving outcomes through greater affordability.
- pt. A-B, 2008. ScienceDirectpt. B, 2008 ScienceDirectedited by Robert K. Poole.Also available: Print – pt. A-B, 2008.
- David M. Glick.
- 2006 CRCnetBASEKimball Nill.
- 2002 CRCnetBASEKimball Nill.
- 2015 SpringerJen-Chywan Wang, Charles Harris, editors.This timely volume provides a comprehensive overview of glucocorticoids and their role in regulating many aspects of physiology and their use in the treatment of disease. The book is broken into four sections that begin by giving a general introduction to glucocorticoids and a brief history of the field. The second section will discuss the effects of glucocorticoids on metabolism, while the third section will cover the effects of glucocorticoids on key tissues. The final section will discuss general topics, such as animal models in glucocorticoid research and clinical implications of glucocorticoid research. Featuring chapters from leaders in the field, this volume will be of interest to both researchers and clinicians.
- 2011Shawn Fletcher Sorrells.Glucocorticoids (GCs) are stress hormones that are well-known for their potent and pleiotropic anti-inflammatory effects. In the injured CNS, their anti-inflammatory properties could be particularly beneficial due to the often detrimental effects of excessive inflammation in the brain. In more recent years, however, it has become clear that GCs do not always decrease inflammation and can even augment aspects of the immune response. The research presented in this doctoral dissertation describes the impact of this increased inflammatory response in the CNS using animal models of excitotoxicity and hypoxia/ischemia. Specifically, both exogenous GC treatments and the endogenously released GCs post-injury were found to increase immune cell activation (both in phenotype and in p65 nuclear translocation) in both rat and mouse models of excitotoxic hippocampal neuron death and in a mouse MCAO stroke model. These increased inflammatory responses are likely to be mediated by an unexpected GC-suppression of several anti-inflammatory cytokines including CX3CL1 and CD22 and failure of GCs to activate some of their normal anti-inflammatory targets like IkBa, IL-1ra, and MKP-1. Furthermore, these GC-augmented inflammatory responses are necessary for GCs to make more neurons die from either of these injuries. Taken together, this work demonstrates that cellular inflammation is not kept in check by GCs in the forebrain; instead, GCs worsen hippocampal and cortical neuron death, at least in part, by increasing the neurotoxicity of CNS inflammation.
- edited by Alton Meister.Also available: Print – 1985
- 2008 Springeredited by Robert W. Gereau IV and Geoffrey T. Swanson.
- 2010 SpringerPhil Skolnick, editor.N-Methyl-d-Aspartate (NMDA) Antagonists for the Treatment of Depression / Phil Skolnick, Piotr Popik and Ramon Trullas -- Ionic Glutamate Modulators in Depression (Zinc, Magnesium) / Bernadeta Szewczyk, Ewa Poleszak, Andrzej Pilc and Gabriel Nowak -- Positive Allosteric Modulation of AMPA Receptors: A Novel Potential Antidepressant Therapy / Eric S. Nisenbaum and Jeffrey M. Witkin -- Glutamatergic Modulators for the Treatment of Major Depressive Disorder: Metabotropic Glutamate Receptors / Jeffrey M. Witkin -- Positive Modulation of AMPA Receptors as a Broad-Spectrum Strategy for Treating Neuropsychiatric Disorders / Gary Lynch, Julie C. Lauterborn and Christine M. Gall -- Activation of Group II Metabotropic Glutamate Receptors (mGluR2 and mGluR3) as a Novel Approach for Treatment of Schizophrenia / Douglas J. Sheffler and P. Jeffrey Conn -- mGluR1 Negative Allosteric Modulators: An Alternative Metabotropic Approach for the Treatment of Schizophrenia / Hisashi Ohta, Hiroshi Kawamoto and Gentaroh Suzuki -- Metabotropic Glutamate Receptors as Targets for the Treatment of Drug and Alcohol Dependence / Svetlana Semenova and Athina Markou -- Metabotropic Approaches to Anxiety / Joanna M. Wieronska, Gabriel Nowak and Andrzej Pilc.
- 2015 SpringerRajkumar Rajendram, Victor R. Preedy, Vinood B. Patel, editors.This text is the first published volume for health professionals and advanced students that examines the biochemistry, clinical nutrition, and therapeutic aspects of glutamine. Drs. Rajendram, Preedy, and Patel are experts in their respective fields and have gathered an august list of contributors that represent the medical profession as well as the academic research community. Glutamine in Clinical Nutrition provides a timely, comprehensive, evidence-based review on the literature that presents the application of current nutritional knowledge by physicians and dietitians and incorporates emerging fields of science and important discoveries. Notable topics include coverage on manganese toxicity and the glutamine-glutamate cycle, glutamine supplementation in HIV, glutamine addiction of cancer cells, glutamine supplementation during major surgery and in intensive care, and glutamine concerns with regards to sepsis, trauma, diabetes, and other diseases. The final chapter provides a wealth of information on web-based resources and suggested readings for the health provider. Written by authors of international and national standing, leaders in the field and trendsetters, Glutamine in Clinical Nutrition is essential reading for nutritionists and dietitians, public health scientists, physicians, epidemiologists, policy makers, and health care professionals of various disciplines.
- 2005 ScienceDirectedited by Helmut Sies, Lester Packer.Also available: Print – 2005
- 2011 SpringerMauro S.G. Pavão, editor.Heparan sulfate proteoglycan in inflammation and angiogenesis / Lianchun Wang -- Heparan sulfate proteoglycans in infection / Allison H. Bartlett and Pyong Woo Park -- Glycans in cancer / Lubor Borsig -- Glycosaminoglycans in atherosclerosis and thrombosis / C.P. Vicente, J.A.P. Godoy, and C.C. Werneck -- Glycans in embryonic stem cells / Claire Pickford ... [et al.] -- Heparan sulfate proteoglycans in cancer therapy / Ezeddin Salem Gassar, Sherif A. Ibrahim, and Martin Götte -- Structure and biological activities of glycosaminoglycan analogs from marine invertebrates : new therapeutic agents? / Eliene O. Kozlowski ... [et al.]
- 2011 Springeredited by Lillian F. Lien, Mary E. Cox, Mark N. Feinglos, Leonor Corsino ; foreword by Guillermo Umpierrez.Physiology of diabetes mellitus and types of insulin -- Subcutaneous insulin: a guide for dosing regimens in the hospital -- IV insulin infusions: how to use an "insulin drip" -- Laboratory testing in hospitalized patients with diabetes mellitus -- Inpatient diabetes education: realistic and evidence-based -- Hyperglycemic emergencies: diabetic ketoacidosis and hyperosmolar hyperglycemic state -- Medical nutrition therapy in the hospital -- Insulin pumps and glucose sensors in the hospital -- Non-insulin antidiabetic medications in the inpatient setting -- Hypoglycemia -- Transitioning to outpatient care -- Management of hyperglycemia associated with enteral and parenteral nutrition -- When to consult endocrinology -- Frequently asked questions.
- 2007 SpringerAkhlaq A. Farooqui and Lloyd A. Horrocks.
- 2006 ScienceDirectedited by Minoru Fukuda.
- 2010 ScienceDirectedited by Minoru Fukuda.
- 2005 Springeredited by John S. Axford.Also available: Print – 2005
- 2006 Springer Protocolsedited by Inka Brockhausen.Gene expression analysis of glycosylation-related genes by real-time polymerase chain reaction / Juan J. Garcia-Vallejo ... [et al.] -- Analysis of the glycodynamics of primary osteoblasts and bone cancer cells / Inka Brockhausen-Schutzbach, Xiaojing Yang, and Mark Harrison -- Micromethods for the characterization of lipid a core and o-antigen lipopolysaccharide / Cristina L. Marolda ... [et al.] -- Assays for a galactosyltransferase involved in the assembly of the O7 antigen repeat unit of escherichia coli / Inka Brockhausen-Schutzbach ... [et al.] -- High-throughput quantitation of metabolically labeled anionic glycoconjugates by scintillation proximity assay utilizing binding to cationic dyes / Karen J. Rees-Milton and Tassos P. Anastassiades -- Quantitative analysis of mucins in mucosal secretions using indirect ELISA / Pablo Argueso and Ilene K. Gipson -- Molecular dissection of the mouse zona pellucida: an electron microscopic perspective utilizing high-resolution colloidal-gold labeling methods / Frederick W. K. Kan -- Soluble adamantly glycosphingolipid analogs as probes of glycosphingolipid function / Clifford Lingwood ... [et al.] -- Diagnosis of Krabbe disease by use of a natural substrate / John W. Callahan and Marie-Anne Skomorowski -- In vitro assays of the functions of calnexin and calreticulin, lectin-chaperones of the endoplasmic reticulum / Breanna S. Ireland, Monika Niggemann, and David B. Williams -- Quantitative measurement of selectin-ligand interactions: assays to identify a sweet pill in a library of carbohydrates / Mark E. Beauharnois, Sriram Neelamegham, and Khushi L. Matta -- Sialic acid-binding specificities of siglecs / Nadine Bock and Soerge Kelm. The application of fluorophore-assisted carbohydrate -- Electrophoresis for the study of the dolichol pyrophosphate-linked oligosaccharides pathway in cell cultures and animal tissues / Ningguo Gao -- Partial purification of mannosylphosphorylundecaprenol synthase from micrococcus luteus: a useful enzyme for the biosynthesis of a variety of mannosylphosphorylpolyisoprenol products / Jeffrey S. Rush and Charles J. Waechter -- Assay of dolichyl-phospho-mannose synthase reconstituted in a lipid matrix / John S. Schutzbach -- O-mannosylation in mammalian cells / Tamao Endo and Hiroshi Manya -- Methods for analysis of unusual forms of o-glycosylation / Aleksandra Nita-Lazar and Robert S. Haltiwanger -- Structural analysis of naturally occurring sialic acids / Johannis P. Kamerling and Gerrit J. Gerwig -- Non-radioactive trans-sialidase screening assay / Silke Schrader and Roland Schauer -- Structural determination of o-glycans by tandem mass spectrometry / Catherine Robbe, Jean-Claude Michalski, and Calliope Capon -- Detailed structural analysis of n-glycans released from glycoproteins in SDS-page gel bands using HPLC combined with exoglycosidase array digestions / Louise Royle ... [et al.] -- Molecular modeling of glycosyltransferases / Anne Imberty ... [et al.] -- Galactoside_2,6-sialyltransferase (st6gal.i) and the sialyl_2,6-galactosyl-linkage in tissues and cell lines / Fabio Dall'Olio, Nadia Malagolini, and Mariella Chiricolo -- Visualizing intracellular distribution and activity of core 2 _(1,6)n-acetylglucosaminyltransferase-I (C2GNT-I) in living cells / Maelle Prorok-Hamon, Sylvie Mathieu, and Assou El-Battari --
- 2015 Springer Protocolsedited by Alexandra Castilho.Current approaches to engineering N-linked protein glycosylation in bacteria / Andreas Naegeli and Markus Aebi -- Inverse metabolic engineering for enhanced glycoprotein production in Escherichia coli / Stephen R. P. Jaffé, Benjamin Strutton, Jagroop Pandhal, and Phillip C. Wright -- GlycoSNAP : a high-throughput screening methodology for engineering designer glycosylation enzymes / Anne A. Ollis, Yi Chai, and Matthew P. DeLisa -- Production of glycoproteins with asparagine-linked N-acetylglucosamine in Escherichia coli / Flavio Schwarz and Markus Aebi -- Glyco-engineering O-antigen-based vaccines and eiagnostics in E. coli / Nicolas F. Vozza and Mario F. Feldman -- Progress in yeast glycosylation engineering / Stephen R. Hamilton and Dongxing Zha -- Protein production with a Pichia pastoris OCH1 knockout strain in fed-batch mode / Christoph Gmeiner and Oliver Spadiut -- Engineering the Pichia pastoris N-glycosylation pathway using the GlycoSwitch technology / Bram Laukens, Charlot De Wachter, and Nico Callewaert -- Development of a valuable yeast strain using a novel mutagenesis technique for the effective production of therapeutic glycoproteins / Hiroko Abe and Ken-ichi Nakayama -- An overview and history of glyco-engineering in insect expression systems / Christoph Geisler, Hideaki Mabashi-Asazuma, and Donald L. Jarvis 11 SweetBac : applying multiBac technology towards flexible modification of insect cell glycosylation / Dieter Palmberger and Dubravko Rendic -- Engineering sialic acid synthesis ability in insect cells / Karthik Viswanathan, Someet Narang, and Michael J. Betenbaugh -- Engineering N-glycosylation pathway in insect cells : suppression of [beta]-N-acetylglucosaminidase and expression of [beta]-1,4-galactosyltransferase / Yeon Kyu Kim and Hyung Joon Cha -- N-glyco-engineering in plants : update on strategies and major achievements / Herta Steinkellner and Alexandra Castilho -- Gene targeting for precision glyco-engineering : production of biopharmaceuticals devoid of plant-typical glycosylation in moss bioreactors / Eva L. Decker, Gertrud Wiedemann, and Ralf Reski -- Im"plant"ing of mammalian glycosyltransferase gene into plant suspension-cultured cells using agrobacterium-mediated transformation / Hiroyuki Kajiura and Kazuhito Fujiyama -- Transient glyco-engineering of N. benthamiana aiming at the synthesis of multi-antennary sialylated proteins / Andreas Loos and Alexandra Castilho -- Subcellular targeting of proteins involved in modification of plant N- and O-glycosylation / Martina Dicker, Jennifer Schoberer, Ulrike Vavra, and Richard Strasser -- Assembly of multigene constructs using golden gate cloning / Sylvestre Marillonnet and Stefan Werner -- Strategies for engineering protein N-glycosylation pathways in mammalian cells / Qiong Wang, Mark Stuczynski, Yuan Gao, and Michael J. Betenbaugh -- Glycan remodeling with processing inhibitors and lectin- resistant eukaryotic cells / Veronica T. Chang, Robert A. Spooner, Max Crispin, and Simon J. Davis -- Production of highly sialylated recombinant glycoproteins using Ricinus communis agglutinin-I-resistant CHO glycosylation mutants / John S. Y. Goh, Kah Fai Chan, and Zhiwei Song -- Metabolic glyco-engineering in eukaryotic cells and selected applications / Friedrich Piller, Aline Mongis, and Véronique Piller -- Evaluation of quenching and extraction methods for nucleotide/nucleotide sugar analysis / Katrin Braasch, Carina Villacrés, and Michael Butler -- Chemoenzymatic glyco-engineering of monoclonal antibodies / John P. Giddens and Lai-Xi Wang -- Chemical polysialylation of recombinant human proteins / Ivan V. Smirnov, Ivan I. Vorobiev, Alexey A. Belogurov, Dmitry D. Genkin, Sergey M. Deyev, and Alexander G. Gabibov -- Site-specific glycosylation profiling using liquid chromatography-tandem mass spectrometry (LC-MS) / Clemens Gruber and Friedrich Altmann -- Mass spectrometric analysis of oligo- and polysialic acids / Christina E. Galuska, Kai Maass, and Sebastian P. Galuska -- Isomer-specific analysis of released N-glycans by LC-ESI MS/MS with porous graphitized carbon / Daniel Kolarich, Markus Windwarder, Kathirvel Alagesan, and Friedrich Altmann.
- 2015 Springer Protocolsedited by Thomas Lütteke, Martin Frank.Annotation of glycomics MS and MS/MS spectra using the glycoworkbench software tool -- Glycobase and autogGU : resources for interpreting HPLC-glycan data -- NMR chemical shift prediction of glycans : application of the computer program CASPER in structural analysis -- Handling and conversion of carbohydrate sequence formats and monosaccharide notation -- Bacterial, plant, and fungal carbohydrate structure databases : daily usage -- Using NMR data on GLYCOSCIENCES.de -- Glycomic analysis using KEGG GLYCAN -- GlycomeDB -- Eukaryotic glycosylation : online methods for site prediction on protein sequences -- Analyzing glycan structure synthesis with the glycan pathway predictor (GPP) tool -- Functional network in posttranslational modifications : Glyco-Net in Glycoconjugate Data Bank -- JCGGDB : Japan Consortium for Glycobiology and Glycotechnology Database -- Glycan array data management at Consortium for Functional Glycomics -- Analyzing glycan-binding patterns with the profilepSTMM tool -- Exploring the specificities of glycan-binding proteins using glycan array data and the GlycoSearch software -- Statistical analysis of amino acids in the vicinity of carbohydrate residues performed by GlyVicinity -- Tools to assist determination and validation of carbohydrate 3D structure data -- Glyco3D : a portal for structural glycosciences -- Solution conformation of carbohydrates : a view by using NMR assisted by modeling -- Informing saccharide structural NMR studies with density functional theory calculations -- Energy maps for glycosidic linkage conformations -- Conformational analysis of oligosaccharides and polysaccharides using molecular dynamics simulations -- Molecular dynamics simulations of membrane- and protein-bound glycolipids using GLYCAM -- Lipopolysaccharide membrane building and simulation -- Molecular dynamics simulations of glycoproteins using CHARMM -- Calculating binding free energies for protein-carbohydrate complexes -- Scoring functions for AutoDock -- Structures of glycans bound to receptors from saturation transfer difference (STD) NMR spectroscopy : quantitative analysis by using CORCEMA-ST -- QM/MM methods for studying enzymatic reactions of glycosyltransferases.
- edited by Minoru Fukuda.Carbohydrate-protein interactions, physical measurements -- Phage display library -- Glycosyltransferase expression profiling -- CHO mutants in glycan biosynthesis -- Function of sulfation -- Functions revealed by forced expression or gene knockout.
- 2010 ScienceDirectedited by Minoru Fukuda.
- 2009 Springer Protocolsedited by Nicolle H. Packer and Niclas G. Karlsson.Analysis of N- and O-linked glycans from glycoproteins using MALTI-TOF mass spectrometry / Willy Morelle ... [et al.] -- Infrared multiphoton dissociation mass spectrometry for structural elucidation of oligosaccharides / Bensheng Li ... [et al.] -- Mass spectrometry of N-linked glycans / Parastoo Azadi and Christian Heiss -- Solid-phase permethylation for glycomic analysis / Yehia Mechref, Pilsoo Kang, and Milos V. Novotny -- Method for investigation of oligosaccharides using phenylhydrazine derivatization / Erika Lattová and Hélène Perreault -- Two-dimensional HPLC separation with reverse-phase-nano-LC-MS/MS for the characterization of glycan pools after labeling with 2-aminobenzamide / Manfred Wuhrer, Carolien A.M. Koeleman, and André M. Deelder -- Capillary lectin-affinity electrophoresis for glycan analysis / Kazuaki Kakehi and Mitsuhiro Kinoshita -- Analysis of methylated O-glycan alditols by reversed-phase nanoLC coupled CAD-ESI mass spectrometry / Franz-Georg Hanisch and Stefan Müller -- High-throughput and high-sensitivity nano-LC/MS and MS/MS for O-glycan profiling / Hasse Karlsson ... [et al.] -- Collision-induced dissociation tandem mass spectrometry for structural elucidation of glycans / Bensheng Li ... [et al.] -- The structural elucidation of glycosaminoglycans / Vikas Prabhakar, Ishan Capila, and Ram Sasisekharan -- Labelling heparan sulphate saccharides with chromophore fluorescence and mass tags for HLC and MS separations / Mark Skidmore ... [et al.] -- Small-scale enzymatic digestion of glycoproteins and proteoglycans for analysis of oligosaccharides by LC-MS and FACE gel electrophoresis / Ruby P. Estrella ... [et al.] -- Enrichment strategies for glycopeptides / Shigeyasu Ito, Ko Hayama, and Jun Hirabayashi -- Introductory glycosylation analysis using SDS-PAGE and peptide mass fingerprinting / Nicole Wilson, Raina Simpson, and Catherine Cooper-Liddell -- Characterization of N-linked glycosylation on recombinant glycoproteins produced in Pichia pastoris using ESI-MS and MALDI-TOF / Bing Gong ... [et al.] -- N-glycosylation site analysis of human platelet proteins by hydrazide affinity capturing and LC-MS/MS / Urs Lewandrowski and Albert Sickmann -- LC/MSn for glycoprotein analysis : N-linked glycosylation analysis and peptide sequencing of glycopeptides / Nana Kawasaki, Satsuki Itoh, and Teruhide Yamaguchi -- Detecting the "O-GlcNAcome" : detection, purification, and analysis of O-GlcNAc modified proteins / Natasha E. Zachara -- Preparation of a glycan library using a variety of glycosyltrasferases [i.e. glycosyltransferases] / Hiromi Ito ... [et al.] -- Data mining the PDB for glyco-related data / Thomas Lütteke and Claus-W. von der Lieth -- Saccharide microarrays for high-throughput interrogation of glycan-protein binding interactions / Andrew K. Powell, Zheng-liang Zhi, and Jeremy E. Turnbull -- Glocosaminoglycan characterization methodologies probing biomolecular interactions / Vikas Prabhakar, Ishan Capila, and Ram Sasisekharan -- Development and characterization of antibodies to carbohydrate antigens / Jamie Heimburg-Molinaro and Kate Rittenhouse-Olson -- Inhibition of glcosyltransferase activities as the basis for drug development / John Schutzbach and Inka Brockhausen -- Saturation transfer difference NMR spectroscopy as a technique to investigate protein-carbohydrate interactions in solution / Thomas Haselhorst, Anne-Christin Lamerz, and Mark von Izstein.
- 2015 Springer Protocolsedited by Kuberan Balagurunathan, Hiroshi Nakato, Umesh R. Desai.Automated Synthesis of Chondroitin Sulfate Oligosaccharides / Chien-Fu Liang, Heung Sik Hahm, and Peter H. Seeberger -- Enzymatic Synthesis of Heparan Sulfate and Heparin / April Joice [and six others] -- Production of Size-Defined Heparosan, Heparan Sulfate, and Heparin Oligosaccharides by Enzymatic Depolymerization / Spencer Brown and Balagurunathan Kuberan -- Chemical Modification of Heparin and Heparosan / Karthik Raman, Balagurunathan Kuberan, and Sailaja Arungundram -- Synthesis of Sulfur Isotope-Labeled Sulfate Donor, 3'-Phosphoadenosine-5'- Phosphosulfate, for Studying Glycosaminoglycan Functions/ Caitlin Mencio [and three others] -- Preparation of Isotope-Enriched Heparan Sulfate Precursors for Structural Biology Studies / Xylophone V. Victor [and three others] -- Synthesis of Glycosaminoglycan Mimetics Through Sulfation of Polyphenols / Rami A. Al-Horani [and three others] -- Synthesis of Selective Inhibitors of Heparan Sulfate and Chondroitin Sulfate Proteoglycan Biosynthesis / Caitlin Mencio [and three others] -- Ascidian (Chordata-Tunicata) Glycosaminoglycans : Extraction, Purification, Biochemical, and Spectroscopic Analysis / Mauro S.G. Pavão -- Human Blood Glycosaminoglycans : Isolation and Analysis / Md. Ferdous Anower-E-Khuda and Koji Kimata -- Chromatographic Molecular Weight Measurements for Heparin, Its Fragments and Fractions, and Other Glycosaminoglycans / Barbara Mulloy and John Hogwood -- Mass Spectrometric Methods for the Analysis of Heparin and Heparan Sulfate / Miroslaw Lech, Ishan Capila, and Ganesh V. Kaundinya -- Validated Capillary Electrophoretic Assays for Disaccharide Composition Analysis of Galactosaminoglycans in Biologic Samples and Drugs/Nutraceuticals / Athanasia P. Asimakopoulou [and five others] -- Fast Screening of Glycosaminoglycan Disaccharides by Fluorophore-Assisted Carbohydrate Electrophoresis (FACE) : Applications to Biologic Samples and Pharmaceutical Formulations / Evgenia Karousou [and seven others] -- Capillary Electrophoretic Analysis of Isolated Sulfated Polysaccharides to Characterize Pharmaceutical Products / Zachary Shriver and Ram Sasisekharan -- Methods for Measuring Exchangeable Protons in Glycosaminoglycans / Consuelo N. Beecher and Cynthia K. Larive -- Heparan Sulfate Structure : Methods to Study N-Sulfation and NDST Action / Anders Dagälv [and five others] -- Analysis of Hyaluronan Synthase Activity / Davide Vigetti [and three others] -- A Rapid, Nonradioactive Assay for Measuring Heparan Sulfate C-5 Epimerase Activity Using Hydrogen/Deuterium Exchange-Mass Spectrometry / Ponnusamy Babu [and three others] -- Aggrecan : Approaches to Study Biophysical and Biomechanical Properties / Hadi Tavakoli Nia, Christine Ortiz, and Alan Grodzinsky -- Use of Flow Cytometry for Characterization and Fractionation of Cell Populations Based on Their Expression of Heparan Sulfate Epitopes / Rebecca J. Holley [and five others] -- A Transgenic Approach to Live Imaging of Heparan Sulfate Modification Patterns / Matthew Attreed and Hannes E. Bülow -- Informatics Tools to Advance the Biology of Glycosaminoglycans and Proteoglycans / Lewis J. Frey -- Designing "High-Affinity, High-Specificity" Glycosaminoglycan Sequences Through Computerized Modeling / Nehru Viji Sankaranarayanan [and three others] -- Using Isothermal Titration Calorimetry to Determine Thermodynamic Parameters of Protein-Glycosaminoglycan Interactions/ Amit K. Dutta, Jörg Rösgen, and Krishna Rajarathnam -- Characterizing Protein-Glycosaminoglycan Interactions Using Solution NMR Spectroscopy / Prem Raj B. Joseph, Krishna Mohan Poluri, Krishna Mohan Sepuru, and Krishna Rajarathnam -- Glycosaminoglycan-Protein Interaction Studies Using Fluorescence Spectroscopy / Rio S. Boothello, Rami A. Al-Horani, and Umesh R. Desai -- Studying Glycosaminoglycan-Protein Interactions Using Capillary Electrophoresis / Aiye Liang and Umesh R. Desai -- Histochemical Analysis of Heparan Sulfate 3-O-Sulfotransferase Expression in Mouse Brain / Tomio Yabe and Nobuaki Maeda -- Keratan Sulfate : Biosynthesis, Structures, and Biological Functions / Kenji Uchimura -- The Sulfs : Expression, Purification, and Substrate Specificity / Kenji Uchimura -- The Detection of Glycosaminoglycans in Pancreatic Islets and Lymphoid Tissues / Marika Bogdani [and five others] -- Nonradioactive Glycosyltransferase and Sulfotransferase Assay to Study Glycosaminoglycan Biosynthesis / Cheryl M. Ethen [and five others] -- Mapping Proteoglycan Functions with Glycosidases / Mauricio Cortes, Leslie K. Cortes, and Nancy B. Schwartz -- Cell Substrate Patterning with Glycosaminoglycans to Study Their Biological Roles in the Central Nervous System / Tony W. Hsiao [and three others] -- Analyzing the Role of Heparan Sulfate Proteoglycans in Axon Guidance In Vivo in Zebrafish / Fabienne E. Poulain -- Murine Models in the Evaluation of Heparan Sulfate-Based Anticoagulants / David Gailani, Qiufang Cheng, and Ivan S. Ivanov -- Genetic Approaches in the Study of Heparan Sulfate Functions in Drosophila / Masahiko Takemura and Hiroshi Nakato -- Measuring Sulfatase Expression and Invasion in Glioblastoma / Anna Wade [and three others] -- Synthesis and Biomedical Applications of Xylosides / Mausam Kalita [and four others] -- A Strategic Approach to Identification of Selective Inhibitors of Cancer Stem Cells / Nirmita Patel, Somesh Baranwal, and Bhaumik B. Patel -- Analysis of the Heavy-Chain Modification and TSG-6 Activity in Pathological Hyaluronan Matrices / Mark E. Lauer [and three others] -- Heparan Sulfate Modulates Slit3-Induced Endothelial Cell Migration / Hong Qiu [and three others] -- Glycosaminoglycan Functionalized Nanoparticles Exploit Glycosaminoglycan Functions / James A. Vassie, John M. Whitelock, and Megan S. Lord -- Role of Glycosaminoglycans in Infectious Disease / Akiko Jinno and Pyong Woo Park -- Isolation and Purification of Versican and Analysis of Versican Proteolysis / Simon J. Foulcer, Anthony J. Day, and Suneel S. Apte -- Analysis of Human Hyaluronan Synthase Gene Transcriptional Regulation and Downstream Hyaluronan Cell Surface Receptor Mobility in Myofibroblast Differentiation / Adam C. Midgley and Timothy Bowen.
- 2015 ScienceDirectedited by Richard R. Drake and Lauren E. Ball.
- 2013 Springer Protocolsedited by Alain Beck.Engineering of therapeutic and diagnostic o-glycans on recombinant mucin-type immunoglobulin fusion proteins expressed in CHO cel / Linda Lindberg, Jining Liu, and Jan Holgersson -- Engineering a human-like glycosylation to produce therapeutic glycoproteins based on 6-linked sialylation in CHO cells / Nassimal El Maï [and others] -- Glycoengineered pichia-based expression of monoclonal antibodies / Dongxing Zha -- N-glycosylation humanization for production of therapeutic recombinant glycoproteins in Saccharomyces cerevisiae / Christelle Arico, Christine Bonnet, and Christophe Javaud -- Engineering the baculovirus genome to produce galactosylated antibodies in lepidopteran cells / Sylvie Juliant [and others] -- NanoLC chips MS/MS for the characterization of n-glycopeptides generated from trypsin digestion of a monoclonal antibody / Elsa Wagner-Rousset [and others] -- Cetuximab Fab and Fc n-glycan fast characterization using IdeS digestion and liquid chromatography coupled to electrospray ionization mass spectrometry / Marie-Claire Janin-Bussat [and others] -- Therapeutic antibody glycosylation analysis : a contract research organization perspective in the frame of batch release or comparability support / Arnaud Delobel [and others] -- Mass spectrometric analysis of o-linked oligosaccharides from various recombinant expression systems / Diarmuid T. Kenny [and others] -- Assessing Fc glycan heterogeneity of therapeutic recombinant monoclonal antibodies using NP-HPLC / T. Shantha Raju -- Application of capillary electrophoresis in glycoprotein analysis / Richard R. Rustandi, Carrie Anderson, and Melissa Hamm -- Characterization of glycoprotein biopharmaceutical products by caliper LC90 CE-SDS gel technology / Grace Chen, Sha Ha, and Richard R. Rustandi -- Hydrophobic interaction chromatography to analyze glycoproteins / Richard R. Rustandi -- Lectin glycoprofiling of recombinant therapeutic interleukin-7 / Ludovic Landemarre and Eric Duverger -- Analysis of monoclonal antibodies by sedimentation velocity analytical ultracentrifugation / W. Blaine Stine Jr. -- Noncovalent mass spectrometry for the characterization of antibody/antigen complexes / Cédric Atmanene [and others] -- Conformational analysis of recombinant monoclonal antibodies with hydrogen/deuterium exchange mass spectrometry / Damian Houde and John R. Engen -- Epitope mapping of antibodies by mass spectroscopy : a case study / Victor H. Obungu, Valentina Gelfanova, and Lihua Huang -- Evaluation of antibody-dependent cell cytotoxicity using lactate dehydrogenase (LDH) measurement / Matthieu Broussas, Lucile Broyer, and Liliane Goetsch -- Evaluation of complement-dependent cytotoxicity using ATP measurement and C1q/C4b binding / Lucile Broyer, Liliane Goetsch, and Matthieu Broussas -- Capture of the human IgG1 antibodies by protein A for the kinetic study of h-IgG/FcgR interaction using SPR-based biosensor technology / Thierry Champion and Alain Beck -- Mass spectrometry protocol for the absolute quantification of a monoclonal antibody in serum with immunopurification / François Becher [and others].
- 2013 Springer Protocolsedited by Inka Brockhausen.Glycan microarray screening assay for glycosyltransferase specificities / W. Peng, C.M. Nycholat and N. Razi -- A fluorescence-based assay for core 1 [beta]3galactosyltransferase (T-synthase) activity / T. Ju and R.D. Cummings -- Structural and biochemical analysis of a bacterial glycosyltransferase / F. Zhu ... [et al.] -- Study of the biological functions of mucin type core 3 O-glycans / S.H. Lee and M. Fukuda -- Generation of anti-sulfated glycan antibodies using sulfotransferase-deficient mice / H. Kawashima -- Fluorescent microscopy as a tool to elucidate dysfunction and mislocalization of golgi glycosyltransferases in COG complex depleted mammalian cells / R.A. Willett, I.D. Pokrovskaya and V.V. Lupashin -- A practical approach to reconstruct evolutionary history of animal sialyltransferases and gain insights into the sequence-function relationships of golgi-glycosyltransferases / D. Petit ... [et al.] -- Fluorescent lectin staining of drosophila embryos and tissues to detect the spatial distribution of glycans during development / E. Tian, L. Zhang and K.G. Ten Hagen -- Photoaffinity labeling of protein O-mannosyltransferases of the PMT1/PMT2 subfamily / M. Loibl and S. Strahl -- Enzymatic analysis of the protein O-glycosyltransferase, rumi, acting toward epidermal growth factor-like (egf) repeats / H. Takeuchi and R.S. Haltiwanger -- Enzymatic characterization of recombinant enzymes of O-glcNAc cycling / E.J. Kim and J.A. Hanover -- Antibodies and activity measurements for the detection of o-glcnac transferase and assay of its substrate, UDP-glcNAc / T. Lefebvre ... [et al.] -- In vitro glycosylation assay for bacterial oligosaccharyltransferases / M.A. Musumeci, M.V. Ielmini and M.F. Feldman -- In vitro UDP-sugar:Undecaprenyl-phosphate sugar-1-phosphate transferase assay and product detection by thin layer chromatography / K.B. Patel and M.A. Valvano -- In vitro O-antigen ligase assay / X. Ruan and M.A. Valvano -- Functional identification of bacterial glucosyltransferase WbdN / Y. Gao, A. Vinnikova and I. Brockhausen -- Methods for the pasteurella glycosaminoglycan synthases: Enzymes that polymerize hyaluronan, chondroitin, or heparosan chains / P.L. Deangelis -- Methods for measuring class i membrane-bound hyaluronan synthase activity / P.H. Weigel, A.J. Padgett-McCue and B.A. Baggenstoss -- Creation and characterization of glycosyltransferase mutants of Trypanosoma brucei / L. Izquierdo, M.L. Guther and M.A. Ferguson -- Mannose-6-phosphate: A regulator of LLO destruction / N. Gao and M.A. Lehrman -- N-acetylglucosaminyltransferase (GnT) assays using fluorescent oligosaccharide acceptor substrates: GnT-III, IV, V, and IX (GnT-Vb) / S. Takamatsu ... [et al.] -- A method for determination of UDP-GlcNAc: GlcNAc[beta]1-6(GlcNAc[beta]1-2)man[alpha]1-r [GlcNAc to man] beta1-4n-acetylglucosaminyltransferase vi activity / T. Taguchi and N. Taniguchi -- In vitro assays of orphan glycosyltransferases and their application to identify notch xylosyltransferases / M.K. Sethi ... [et al.] -- In vitro folding of [beta]-1,4galactosyltransferase and polypeptide-[alpha]-N-acetylgalactosaminyltransferase from the inclusion bodies / B. Ramakrishnan and P.K. Qasba -- An assay for [alpha] 1,6-fucosyltransferase (FUT8) activity based on the HPLC separation of a reaction product with fluorescence detection / H. Ihara ... [et al.] -- Immunodetection of glycosyltransferases in gastrointestinal tissues / J. Gomes and C.A. Reis -- Glycosyltransferases in chemo-enzymatic synthesis of oligosaccharides / B. Tefsen and I. van Die -- Tumor targeting by a carbohydrate ligand-mimicking peptide / S. Hatakeyama ... [et al.] -- Glycoengineering of human cell lines using zinc finger nuclease gene targeting: Simple cells with homogeneous GalNAc O-glycosylation allow isolation of the O-glycoproteome by one-step lectin affinity chromatography / C. Steentoft, E.P. Bennett and H. Clausen -- Generation of monoclonal antibodies to native active human glycosyltransferases / M.B. Vester-Christensen ... [et al.].
- 2007 Springer Protocolsedited by Richard J. Sugrue.The use of monoclonal antibodies and lectins to identify changes in viral glycoproteins that are influenced by glycosylation : the case of respiratory syncytial virus attachment (G) glycoprotein / Joanna Rawling and José A. Melero -- Expression, glycosylation, and modification of the spike (S) glycoprotein of SARS-CoV / Shuo Shen, Timothy H.P. Tan, and Yee-Joo Tan -- Analysis of glycoproteins of viruses in the family bunyaviridae / Xiaohong Shi and Richard M. Elliott -- Secretion of respiratory syncytial virus fusion protein from insect cells using the baculovirus expression system / Boon-Huan Tan, Gaie Brown, and Richard J. Sugrue -- Characterization of the dengue virus envelope glycoprotein expressed in Pichia pastoris / Boon-Huan Tan, Jian Lin Fu, and Richard J. Sugrue -- Cloning, expression, and functional analysis of patient-derived hepatitis C virus glycoproteins / Alexander W. Tarr ... [et al.]. Viruses and glycosylation : an overview / Richard J. Sugrue -- Interaction between respiratory syncytial virus and glycosaminoglycans, including heparan sulfate / Louay K. Hallak, Steven A. Kwilas, and Mark E. Peeples -- Expression of the severe acute respiratory syndrome coronavirus 3a protein and the assembly of coronavirus-like particles in the baculovirus expression system / Sehaam Khan, Mah-Lee Ng, and Yee-Joo Tan -- The C type lectins DC-SIGN and L-SIGN : receptors for viral glycoproteins / Pierre-Yves Lozach ... [et al.] -- Functional analysis of the N-linked glycans within the fusion protein of respiratory syncytial virus / Ping Li ... [et al.] -- Expression and purification of viral glycoproteins using recombinant vaccinia viruses for functional and structural studies / Zhu-Nan Li and David A. Steinhauer -- The use of two-dimensional SDS-PAGE to analyze the glycan heterogeneity of the respiratory syncytial virus fusion protein / Terence P. McDonald and Richard J. Sugrue --
- 2011Drew Alexander Hall.Nanotechnology has had a transformative effect on medical diagnostics due to the influx of new sensing modalities and transducers. Magnetic nanotechnologies, in particular, have shown significant potential in several areas of nanomedicine such as imaging, therapeutics, and early disease detection. Giant magnetoresistive spin-valve (GMR SV) sensors, commonly used in hard disk drives, coupled with magnetic nanotags have shown great promise as biosensors. In this work, we present several custom designed circuit interface and readout systems tailored to specific application spaces and their unique needs. Taken together, we have demonstrated that innovative electronic circuits play an indispensable role in unlocking the tremendous potential of nanosensors in the biomedical arena. The first system was designed for ultrasensitive early cancer diagnostics and built using off-the-shelf components for an 8x8 array of GMR SV sensors. At the core of this design, we demonstrate a new circuit architecture based on a transimpedance amplifier (TIA) with a carrier suppression technique to reduce the dynamic range requirement and a multiplexing scheme to reduce the readout time. This system is capable of real-time, multiplex detection with a detection limit of 5 femtomolar (fM) and over 6 orders of linear dynamic range. The second system is a miniaturized, portable platform called the nanoLAB. Although there is a growing need for point-of-care (POC) testing for global health, the current options are bulky, slow, expensive, and often not sensitive. The nanoLAB addresses these needs and pushes the state of the art with sensitive 8-plex detection using a wash-free assay that can be run by anyone, anywhere. This platform was tested and validated using human immunodeficiency virus (HIV) biomarkers with detection down to 50 fM in as little as 15 minutes. We also show how a GMR SV biosensor can be integrated into a continuous time sigma delta modulator. This proof-of-concept hybrid sigma delta modulator has a peak SNR of 99.3 dB and a dynamic range of over 92 dB in a 1 kHz bandwidth using the sensor as part of the first integrator. The carrier suppression and multiplexing concepts were also incorporated into the hybrid sigma delta modulator. Lastly, we conclude by describing an integrated platform for a large 16x16 array of GMR SV sensors implemented in a 0.18 [mu]m CMOS technology. Arranged like an imager chip, each of the 16 column level readout channels contains an analog front-end and an analog-to-digital converter. Each readout channel occupies less than 0.2 mm^2 of chip area and consumes 3.4 mW of power. This system is designed as a replacement for optical protein microarrays while being fully quantitative and providing real-time readout.
- 2008 HighWireedited by Gilles Montalescot.
- 2012Victoria Sweet."San Francisco's Laguna Honda Hospital is the last almshouse in the country, a descendant of the Hotel-Dieu (God's Hotel) that cared for the sick in the Middle Ages. Ballet dancers and rock musicians, professors and thieves--"anyone who had fallen, or, often, leapt, onto hard times" and needed extended medical care-ended up here. So did Victoria Sweet, who came for two months and stayed for twenty years. Laguna Honda, lower tech but human paced, gave Sweet the opportunity to practice a kind of attentive medicine that has almost vanished. Gradually, the place transformed the way she understood her work. Alongside the modern view of the body as a machine to be fixed, her extraordinary patients evoked an older idea, of the body as a garden to be tended. God's Hotel tells their story and the story of the hospital itself, which, as efficiency experts, politicians, and architects descended, determined to turn it into a modern "health care facility," revealed its own surprising truths about the essence, cost, and value of caring for body and soul"--Provided by publisher. "Choosing service in the last remaining almshouse in America, and tracing our understanding of medicine back to its medieval roots, a physician uncovers lost lessons in the care of body and soul"--Provided by publisher. Includes detailed explorations of Hildegard's medical practice and its occasional unexpected utility for modern problems.
- Gold mirrors and tongue reflections : the cornerstone classics of Chinese medicine tongue diagnosis - The Ao shi shang han jin jing lu, and The Shang han she jian2013[commentary and translations by] Ioannis Solos ; forewords by Professor Liang Rong and Professor Chen Jia-xu.
- 2013 ClinicalKeyAry L. Goldberger, Zachary D. Goldberger, Alexei Shvilkin.Key concepts -- ECG basics : waves, intervals, and segments -- ECG leads -- Understanding the normal ECG -- Electrical axis and axis deviation -- Atrial and ventricular enlargement -- Ventricular conduction disturbances : bundle branch blocks and related abnormalities -- Myocardial infarction and ischemia, I : ST segment elevation and non-Q wave -- Syndromes -- Myocardial infarction and ischemia, II : non-ST segment elevation and non-Q wave syndromes -- Drug effects, electrolyte abnormalities, and metabolic effects -- Pericardial, myocardial and pulmonary syndromes -- Wolff-Parkinson-White preexcitation syndromes -- Sinus and escape rhythms -- Supraventricular arrhythmias, part I : premature beats and paroxysmal supraventricular tachycardias (PSVTS) -- Supraventricular arrhythmias, part II : atrial flutter and atrial fibrillation -- Ventricular arrhythmias -- Atrioventricular (AV) conduction abnormalities : delays, blocks, and dissociation syndromes -- Digitalis toxicity -- Sudden cardiac arrest and sudden cardiac death -- Bradycardias and tachycardias : review and differential diagnosis -- Pacemakers and implantable cardioverter-defibrillators (ICDs) : essentials for clinicians -- How to interpret an ECG -- Limitations and uses of the ECG -- ECG differential diagnoses : instant reviews.
- 2008 Springeredited by Gary W. Barrett, George A. Feldhamer.The golden mouse : a levels-of-organization perspective / Gary W. Barrett -- The golden mouse : taxonomy and natural history / George A. Feldhamer and Donald W. Linzey -- Population ecology of the golden mouse / Robert K. Rose -- Community ecology of the golden mouse / Cory C. Christopher and Guy N. Cameron -- Ecosystem ecology of the golden mouse / Steven W. Seagle -- Landscape ecology of the golden mouse / Jerry O. Wolff and Gary W. Barrett -- Relative abundance and conservation : is the golden mouse a rare species? / George A. Feldhamer and Anita T. Morzillo -- The golden mouse : a model of energetic efficiency / John D. Peles and Gary W. Barrett -- Nesting ecology of the golden mouse : an oikos engineer / Thomas M. Luhring and Gary W. Barrett -- Ectoparasites, bots, and vector-borne diseases associated with the golden mouse / Lance A. Durden -- Aesthetic landscapes of the golden mouse / Terry L. Barrett and Gary W. Barrett -- Future challenges and research opportunities : what do we really know? / Gary W. Barrett and George A. Feldhamer.
- 2015 AccessEmergency Medicine[edited by] Robert S. Hoffman, Mary Ann Howland, Neal A. Lewin, Lewis S. Nelson, Lewis R. Goldfrank ; editor emeritus Neal E. Flomenbaum.Pt. A: The general approach to medical toxicology -- Pt. B: The fundamental principles of medical toxicology -- Sect. I: Biochemcial and molecular basis -- Sect. II: Pathophysiologic basis: organ systems -- Sect. III: Special populations -- Pt. C: The clinical basis of medical toxicology -- Sect. I: A: Analgesics and antinflammatory medications -- B: Food, diet, and nutrition -- C: Pharmaceuticals -- D: Antimicrobials -- E: Cardiopulmonary medications -- F: Anesthetics and related medications -- G: Psychotropics -- H: Substances of abuse -- I: Metals -- J: Household products -- K: Pesticides -- L: Natural toxins and envenomations -- M: Occupational and environmental toxins -- N: Disaster preparedness -- Sect. II: Poison centers and epidemiology.
- 2006[edited by] Neal E. Flomenbaum ... [et al.].
- 2016 ClinicalKey[edited by] Lee Goldman, and Andrew I. Schafer.In the 90 years since the first edition of the Cecil Textbook of Medicine was published, almost everything we know about internal medicine has changed. Progress in medical science is now occurring at an ever-accelerating pace, and it is doing so within the framework of transformational changes in clinical practice and the delivery of health care at individual, social, and global levels. However, we have remained true to the tradition of a comprehensive textbook of medicine that carefully explains the why (the underlying pathophysiology of disease) and the how (now expected to be evidence-based from randomized controlled trials and meta-analyses). In short-- Goldman-Cecil Medicine offers definitive, unbiased guidance on the evaluation and management of every medical condition.
- 2012 ScienceDirect[edited by] Lee Goldman, Andrew I. Schafer.Social and ethical issues in medicine -- Principles of evaluation and management -- Preventive and environmental issues -- Aging and geriatric medicine -- Clinical pharmacology -- Genetics -- Principles of immunology and inflammation -- Cardiovascular disease -- Respiratory diseases -- Critical care medicine -- Renal and genitourinary diseases -- Gastrointestinal diseases -- Diseases of the liver, gallbladder, and bile ducts -- Hematologic diseases -- Oncology -- Metabolic diseases -- Nutritional diseases -- Endocrine diseases -- Women's health -- Diseases of bone and mineral metabolism -- Diseases of allergy and clinical immunology -- Rheumatic diseases -- Infectious diseases -- HIV and the acquired immunodeficiency syndrome -- Neurology -- Eye, ear, nose, and throat diseases -- Medical consultation -- Skin diseases.
- 2009 SpringerD. James Morré, Hilton H. Mollenhauer.
- 2016 SpringerNao Suzuki, Jacques Donnez, editors.This book is a practical guide to the cryopreservation and transplantation of oocytes, embryos, and ovarian and testicular tissue for fertility preservation. Illustrated with a wealth of figures and photos, it provides updated techniques for clinicians, technicians, and researchers. This book also gives insights into in vitro activation (IVA), in vitro growing (IVG), and in vitro maturation (IVM), with both basic research and future directions. These techniques combined with cryopreservation will improve the chances of reproduction. Cryopreservation is essential to protect fertility in cancer patients who undergo treatment with radioiodine or chemotherapy, which may cause damage to their reproductive organs, and also for primary ovarian insufficiency patients. The book also includes a chapter on the risk of the presence of malignant cells in ovarian tissue. Both editors are pioneering researchers in this field.
- 2002 ScienceDirectedited by Ishwar S. Parhar.Section I. Development and cell migration -- Section II. GnRH receptors -- Section III. Physiology and regulation.Also available: Print – 2002
- 2012 SpringerChristoph Faschinger, Anton Hommer.Gonioscopy is a very important differential diagnostic tool that permits assessment of the anterior chamber angle and correct classification of glaucoma as a basis for specific treatment. This book clearly explains how to perform gonioscopy to best effect. The anatomy of the chamber angle is systematically described, and the impact of age, developmental disorders, and other pathologies on the chamber angle is explained. Particular attention is focused on primary and secondary open-angle and angle-closure glaucomas. In each case, the role of gonioscopy in evaluating the chamber angle is described with the help of many photographs and illustrations. The importance of knowledge of the chamber angle for laser treatment and surgery is fully explained, and the impact of medications is discussed. The practitioner will find in Gonioscopy all the information required to use the technique effectively in diagnosis and treatment.
- 2013 SpringerTerrence P. Tougas, Jolyon P. Mitchell, Svetlana A. Lyapustina, editors.Introduction / Terrence P. Tougas, Jolyon P. Mitchell -- Current Approaches to APSD Measurements of OIPs Based on Inertial Impaction / Jolyon P. Mitchell, Daryl L. Roberts -- Physical Causes of APSD Changes in Aerosols from OIPs and Their Impact on CI Measurements / Helen Strickland, Beth Morgan -- Good Cascade Impactor Practices / Jolyon P. Mitchell -- The AIM and EDA Concepts: Why They Are Needed and How They Fit Together / Jolyon P. Mitchell, Terrence P. Tougas -- Product Life Cycle Approach to Cascade Impaction Measurements / Richard Bauer, J. David Christopher -- Theoretical Basis for the EDA Concept / Terrence P. Tougas, Jolyon P. Mitchell -- Performance Characterization of EDA and Its Potential to Improve Decision Making in Product Batch Release / J. David Christopher, Helen Strickland -- Verification of the EDA Concept Through an Assessment of Theoretical Failure Modes, Failure Mode Analysis, and Case Studies with Real Data / Helen Strickland, Beth Morgan -- Validating AIM-Based Instrumentation and Associated Measurement Techniques / Mark Copley, Jolyon P. Mitchell -- The Regulatory and Compendial Pathways to Acceptance for AIM and EDA Concepts / Steven C. Nichols, Jolyon P. Mitchell -- Applying the AIM Concept in Support of Developing Improved In Vitro-In Vivo Relationships for OIPs / Jolyon P. Mitchell, Mark Copley -- Future Directions for the AIM and EDA Concepts / Terrence P. Tougas, Jolyon P. Mitchell -- Conclusions / Terrence P. Tougas, Svetlana A. Lyapustina.
- 2014Barron H. Lerner, MD.The first Dr. Lerner -- Super doctor -- Illness hits home -- The second Dr. Lerner -- Forging my own path -- Treating the whole patient -- Family practitioner -- Growing disillusionment -- Slowing down -- Epilogue.
- G protein coupled receptors. Modeling, activation, interactions and virtual screening — Genetic and biochemical analysis of the Ribonuclease E family of proteins in Escherichia coli (165)
- Genetic and chemical studies towards the mechanistic understanding of Gli activation — Geriatric rheumatology : a comprehensive approach (165)
- Geriatric trauma and critical care — Good doctor : a father, a son, and the evolution of medical ethics (165)
- Good manufacturing practices for pharmaceuticals : a plan for total quality from manufacturer to consumer. 5th ed., rev. and expanded. — Gynecological imaging : a reference guide to diagnosis (162)
- Harrison's Principles of Internal Medicine
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- Surgical Exposures in Orthopaedics
- Mandell, Douglas, & Bennett's Principles & Practice of Infectious Diseases
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