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Books

  • Digital
    Ian M. MacFarlane, Patricia McCarthy Veach, Bonnie S. LeRoy.
    Contents:
    Developing research questions
    Finding sources
    Writing a review of literature
    Ethics in research
    Choosing a paradigm
    Designing a quantitative study
    Quantitative data analysis : I've got data, how do I get answers?
    Conducting qualitative genetic counseling research
    Preparing a manuscript for publication
    Guidelines for directing research.
    Digital Access Oxford 2014
  • Digital/Print
    Elisabetta Baldi, Monica Muratori, editors.
    Summary: There are several types of damage that can be found in the male gamete. Genetic damage in spermatozoa can originate during spermatogenesis, or it can originate during transit in both male and female genital tracts. Damage can also be due to aging, environmental or iatrogenic conditions, as well as to the protocols to cryopreserve and to select spermatozoa in assisted reproduction techniques. This book provides a comprehensive resource for all possible DNA damages in sperm, the relation to fertility and infertility, and possible transgenerational heritable effects.

    Contents:
    Structure of chromatin in spermatozoa
    Genomic changes in spermatozoa of aging male
    Chromosomal aberrations and aneuploidies of spermatozoa
    The sperm epigenome: implications for the embryo
    Environmental epigenetics and effects on male fertility
    Protamine alterations in human spermatozoa
    Sperm DNA fragmentation and base oxidation
    Iatrogenic enetic damage of spermatozoa
    Sperm cryopreservation: effect on chromatin structure
    Sperm selection: effect on sperm DNA quality
    Effect of antioxidant on sperm genetic damage.
    Digital Access Springer 2014
  • Digital
    edited by Elisabetta Baldi, Monica Muratori.
    Summary: There are several types of damage that can be found in the male gamete. This book covers the genetic damage in spermatozoa that can originate during spermatogenesis, or during transit in both male and female genital tracts. Damage can also be due to ageing, environmental or iatrogenic conditions, as well as to the protocols to cryopreserve and to select spermatozoa in assisted reproduction techniques. The purpose of this book is to provide a comprehensive resource for all possible DNA damages in sperm, the relation to fertility and infertility, and possible transgenerational heritable effects.

    Contents:
    Genetic factors affecting sperm chromatin structure
    Mechanisms of origin of chromosome deletions and rearrangements in spermatozoa
    The sperm epigenome: implications for ART outcomes
    Epigenetic transgenerational inheritance
    Environmental genetic and epigenetic sperm alterations
    Sperm DNA fragmentation: mechanisms of origin
    Sperm DNA fragmentation: consequences for reproduction
    Oxidative damage to sperm DNA: attack and defence
    Interventions to prevent sperm DNA damage effects on reproduction.-Cryopreservation of sperm: effects on chromatin and strategies to prevent them
    Effect on sperm DNA quality following sperm selection for ART: new insights
    Sperm DNA damage in cancer patients
    Index.
    Digital Access Springer 2019
  • Digital
    edited by Roy E. Weiss, Samuel Refetoff.
    Contents:
    Mechanisms of mutation
    A clinical guide to monogenic diabetes
    Hypoglycemia
    Functioning pituitary adenomas
    Diabetes insipidus
    States of pituitary hypofunction
    Congenital defects of thyroid hormone synthesis
    Developmental abnormalities of the thyroid
    Syndromes of impaired sensitivity to thyroid hormone
    Molecular diagnosis of thyroid cancer
    Genetics of hyperparathyroidism including parathyroid cancer
    Genetic diagnosis of skeletal dysplasias
    Vitamin d disorders
    Congenital adrenal hyperplasia
    Genetics of adrenocortical tumors (ACT) and hypersecretory syndromes
    Hereditary syndromes involving pheochromocytoma and paraganglioma
    Genetic conditions associated with congenital adrenocortical insufficiency or glucocorticoid and/or mineralocorticoid resistance
    Genetic considerations in the evaluation of menstrual cycle irregularities
    Disorders of sex development
    Androgen insensitivity due to mutations of the androgen receptor
    Obesity
    Syndromes of severe insulin resistance and/or lipodystrophy
    Lipodystrophies
    Multiple endocrine neoplasia type 1 (MEN1)
    Genetics of polyglandular failure
    Genetic diagnosis of growth failure
    Cost-effectiveness of genetic testing for monogenic diabetes
    Genetic counseling: the role of genetic counselors on healthcare provider and endocrinology teams
    Setting up a laboratory
    Introduction to applications of genomic sequencing.
    Digital Access ClinicalKey 2016
  • Digital
    Dilip Nandwani, editor.
    Summary: This book in the series "Sustainable Development and Biodiversity" contains peer-reviewed chapters from leading academicians and researchers around the world in the field of horticulture, plant taxonomy, plant biotechnology, genetics and related areas of biodiversity science centered on genetic diversity. This book includes original research reviews (national, regional and global) and case studies in genetic diversity in fruits and vegetables, horticulture, and ecology from sub-tropical and tropical regions. It is unique as it covers a wide array of topics covering global interests and will constitute valuable reference material for students, researchers, extension specialists, farmers and certification agencies who are concerned with biodiversity, ecology and sustainable development.

    Contents:
    Section 1: Biology and Phylogenetic Diversity
    1. Augmentation of Plant Genetic Diversity in Synecoculture: Theory and Practice in Temperate and Tropical Zones; Masatoshi Funabashi
    2. Amplified Fragment Length Polymorphism based Phylogenetic Relationships of Heirloom Tomato and Dark Green Vegetable Accessions; Ahmad Naseer Aziz
    3. Molecular and Quantitative Genetics of Stone Pine (Pinus pinea); Mutke Regneri Sven et al
    4. Sweetpotato Genetic Resources
    Today and Tomorrow; Robert L. Jarret et al
    Section 2: Genetic Diversity
    5. Genetic Diversity in Vegetable Crops; Dilip Nandwani et al
    6. The Genetic Diversity of Popular African Leafy Vegetables in Western Kenya; Christine Ndinya-Omboko
    7. Genetic Diversity in African Eggplant: A Key Resource for Improving the Crop; Michael Kwabena Osei
    8. Genetic Diversity in Nutritious Leafy Green Vegetable
    Chaya (Cnidoscolus aconitifolius); Roland Ebel et al
    9. Genetic Diversity in Taro (Colocasia esculenta); Susan C. Miyasaka et al
    10. Genetic Diversity in Pitaya; Aroldo Cisneros, Noemi Tel-Zur
    11. Genetic Diversity in Banana; Sanjit Debnath et al
    Section 3. Agrobiodiversity Utilization
    12. The role of agrobiodiversity in sustainable food systems design and management; Ciaccia Corrado et al
    13. Induced Genetic Diversity in Banana; Suprasanna Penna, Mohan Jain
    14. Exploration and Utilization of Genetic Diversity in Tomato; Michael Kwabena Osei et al
    15. Agro-biodiversity adaptation in India for resilience to climate change; Thomas Abraham et al
    Index.
    Digital Access Springer 2019
  • Digital/Print
    Hollaender, Alexander; Setlow, Jane K.
    Digital Access
    Provider
    Version
    Springer
    Springer
    Print Access Request
    Location
    Version
    Call Number
    Items
    Books: General Collection (Downstairs)
    QH442 .G44
    28
  • Digital
    Vijay Rani Rajpal, Deepmala Sehgal, Avinash Kumar, S.N. Raina, editors.
    Summary: Genetic Enhancement of Crops for Tolerance to Abiotic Stress: Mechanisms and Approaches, Volume I provides a consolidated update of the approaches taken to deepen our understanding of plants' morphological, physiological and molecular responses to various abiotic stresses and progresses made in unraveling and understanding the regulatory mechanisms, signaling pathways and cross talk among mechanisms operating under abiotic stress situations in various crops. The book includes articles on the diverse tools and technological approaches the use of which has improved our understanding of the intricate mechanisms operating in crop plants under abiotic stress conditions. The chapters describe the use of various 'omics' platforms such as transcriptomics, metabolomics, proteomics, microRNA and heat shock proteins as molecular players, phytohormone (s) regulation of stress signalling pathways, and various functional genomics approaches adopted by scientists to collate a wealth of information to understand abiotic stress tolerance mechanisms for crop improvement. In addition, chapters have been contributed on the burning topic of the role of chromatin remodeling under stress conditions and on the epigenetic dynamics via histones modifications that can improve stress tolerance in crops by enhancing the stress memory. We are very hopeful that the topics will be useful to a broad community of scientists working in similar areas and the outcomes discussed can provide useful leads to build strategies to generate abiotic stress tolerant varieties.

    Contents:
    Preface
    Acknowledgements
    1. Functional Genomics Approach Towards Dissecting out Abiotic Stress Tolerance Trait in Plants; Sneh L. Singla-Pareek
    2. Plant miRNAome: Cross Talk in Abiotic Stressful Times; P. Suprasanna
    3. Epigenetic Response of Plants to Abiotic Stress: Nature, Consequences and Applications in Breeding; Manoj. K. Dhar
    4. Effect of Drought Stress and Utility of Transcriptomics in Identification of Drought Tolerance Mechanisms in Maize; T. Nepolean
    5. Physiological and Molecular Basis of Abiotic Stress Tolerance in Wheat; H.M. Mamrutha
    6. Molecular Chaperones: Key Players of Abiotic Stress Response in Plants; A. Pareek
    7. Role of Chromatin Assembly and Remodeling in Water Stress Responses in Plants; N. Asharaf
    8. The 'Omics' Approach for Crop Improvement Against Drought Stress; D. Jain
    9. Genomic Strategies for Improving Abiotic Stress Tolerance in Crop Plants; N.R. Yadav
    10. Genomics of Arsenic Stress Tolerance in Plants; P.K. Trivedi
    11. Phytohormones Regulating the Master Regulators of CBF Dependent Cold Stress Signaling Pathway; R. Deswal
    Index.
    Digital Access Springer 2019
  • Digital
    edited by Jeffrey L. Bose.
    Contents:
    Understanding staphylococcal nomenclature / Christina N. Krute and Jeffrey L. Bose
    Restriction-modification systems as a barrier for genetic manipulation of Staphylococcus aureus / Marat R. Sadykov
    Complementation plasmids, inducible gene-expression systems, and reporters for Staphylococci / Ralph Bertram
    De novo assembly of plasmids using yeast recombinational cloning / Ameya A. Mashruwala and Jeffrey M. Boyd
    Splicing by overlap extension PCR to obtain hybrid DNA products / Justin A. Thornton
    Method for preparation and electroporation of S. aureus and S. epidermidis / Melinda R. Grosser and Anthony R. Richardson
    Rapid isolation of DNA from staphylococcus / Kelsey L. Krausz and Jeffrey L. Bose
    Bacteriophage transduction in Staphylococcus aureus : broth-based method / Kelsey L. Krausz and Jeffrey L. Bose
    Bacteriophage transduction in Staphylococcus aureus / Michael E. Olson
    Batch transduction of transposon mutant libraries for rapid phenotype screening in staphylococcus / Katherine L. Maliszewski
    Conjugative transfer in Staphylococcus aureus / Cortney R. Halsey and Paul D. Fey
    Allelic exchange / McKenzie K. Lehman, Jeffrey L. Bose, and Kenneth W. Bayles
    Creation of staphylococcal mutant libraries using transposon Tn917 / Kelly C. Rice
    Generation of a transposon mutant library in Staphylococcus aureus and staphylococcus epidermidis using bursa aurealis / Vijaya Kumar Yajjala ... [et al.]
    Chemical and UV mutagenesis / Jeffrey L. Bose
    Pulse field gel electrophoresis / Batu K. Sharma-Kuinkel, Thomas H. Rude, and Vance G. Fowler Jr.
    RNA-sequencing of Staphylococcus aureus messenger RNA / Ronan K. Carroll, Andy Weiss, and Lindsey N. Shaw
    Quantitative real-time PCR (qPCR) workflow for analyzing Staphylococcus aureus gene expression / April M. Lewis and Kelly C. Rice
    Electrophoretic mobility shiftaAssays / Sarah E. Rowe and James P. O'Gara
    Rapid amplification of cDNA ends for RNA transcript sequencing in staphylococcus / Eric Miller.
    Digital Access Springer 2016
  • Digital
    N. Manikanda Boopathi.
    Summary: This book details basics in genetic linkage mapping, step-by-step procedures to perform marker assisted selection (MAS), achievements made so far in different crops, and the limitations and prospects of MAS in plant breeding.

    Contents:
    Intro
    Preface (Second Edition)
    Contents
    About the Author
    1: Genetic Mapping and Marker-Assisted Selection: Setting the Background
    1.1 Setting the Background
    1.2 Trends in Agricultural Product Demand: Functional Foods and Value-Added Products
    1.3 Evolving New Crop Cultivars: Promises of Conventional Plant Breeding Programs
    1.3.1 Achievements
    1.3.2 Conventional Plant Breeding: Obstacles and Challenges
    1.3.3 Germplasm Exchange: International Laws and Governance
    1.3.4 Biotech Crops and Biosafety Issues 1.3.4.1 Evolving New Cultivars Using Tools of Biotechnology
    1.3.4.2 Plant Tissue Culture-Based Approaches
    1.3.4.3 Genetic Engineering and Transgenic Plants
    1.3.4.4 Biosafety and Other Issues Related to Transgenic Crops
    1.4 Alternative Approach: MAS
    1.5 Scope of Genetic Mapping and Marker-Assisted Selection
    1.6 Need for This Book: What Can Be Expected?
    Critical Thinking Questions
    Bibliography
    Literature Cited
    Additional Readings
    2: Germplasm Characterization: Utilizing the Underexploited Resources
    2.1 Types of Plant Germplasm: Natural Versus Man-Made 2.1.1 Conservation of Naturally Prevailing Plant Germplasm
    2.1.1.1 In Situ Conservation
    2.1.1.2 Ex Situ Conservation
    2.1.2 Conservation of Man-Made Plant Germplasm
    2.1.2.1 Crop-Specific Germplasm Repository
    2.1.2.2 Mutagenized Population
    2.1.2.3 Global Germplasm Resources
    2.2 Germplasm Characterization: Phenotyping for Morphological and Agronomic Characters
    2.2.1 Conventional Methods of Phenotyping: Biotic and Abiotic Stress Resistance, Yield, and Quality Traits
    2.2.2 Recent Developments in Phenomics and Way Forward 2.2.3 Case Study in Rice Germplasm Characterization for Drought Resistance: Formation of the Fundamental Requirements
    2.2.4 Traits Useful for Germplasm Characterization in Rice
    2.3 Allele Mining
    2.3.1 Allele Mining: Basic Considerations
    2.3.2 Insertional Mutagenesis
    2.3.3 Genome Editing Tools and Induced Variations
    2.3.4 TILLING, EcoTILLING, and Self-EcoTILLING
    2.3.5 Mutant-Assisted Gene Identification and Characterization (MAGIC)
    2.3.6 Allele Mining: Challenges and Troubleshooting Perspectives
    2.4 Genetic Diversity and Clustering 2.4.1 Software for Genetic Diversity Analysis
    2.4.2 Principle Behind the Genetic Diversity Analysis
    2.4.3 Principle of Measuring Goodness-of-Fit of a Classification
    2.5 Issues in Genetic Diversity Analysis Using Molecular Markers
    2.5.1 Co-dominant Markers and Similarity Measures
    2.5.2 Dominant Markers and Similarity Measures
    2.6 Diversity and Phylogenetic Tree: Importance in Mapping Population Development
    2.7 DNA Barcoding and Its Utilization in Germplasm Exploitation
    2.8 Parental Selection
    Critical Thinking Questions
    Bibliography
    Literature Cited
    Digital Access Springer 2020
  • Digital
    edited by Anantha Shekhar.
    Summary: "Genetic Models and Molecular Pathways Underlying Autism Spectrum Disorders, Volume 241 provides the most recent information on the animal model systems that are available to study different forms of autism spectrum disorders. In addition to genetically engineered animals that uniquely model genetic forms of ASD, this volume also provides detailed chapters on a variety of specific topics, including an overview of genetic models of ASDs, phenotypic modeling of ASD symptoms, molecular mechanisms of NF1 model of ASD symptoms, ube3a gene dosage disorders, molecular and circuit mechanisms of ASD, circuit dysfunctions in ASD models, ERK signaling in genetic models of ASD, and more"--Publisher's description.

    Contents:
    Overview of genetic models of autism spectrum disorders / Jheel Patel, Jodi L. Lukkes, Anantha Shekhar
    Neurofibromatosis type 1 as a model system to study molecular mechanisms of autism spectrum disorder symptoms / Andrei I. Molosh, Anantha Shekhar
    ERK/MAPK signaling and autism spectrum disorders / Joseph Vithayathil, Joanna Pucilowska, Gary E. Landreth
    From bedside to bench and back: Translating ASD models / Hayley P. Drozd, Sotirios F. Karathanasis, Andrei I. Molosh, Jodi L. Lukkes, ... Anantha Shekhar
    Studying child development in genetic models of ASD / Shruti Garg, Jonathan Green
    Measurement considerations in pediatric research on autism spectrum disorders / Karin S. Walsh, Srishti Rau.
    Digital Access ScienceDirect 2018
  • Digital
    Corrado Angelini.
    Contents:
    Section 1 Muscular Dystrophies
    Duchenne Muscular Dystrophy
    Duchenne Muscular Dystrophy carrier
    Becker Muscular Dystrophy
    Emery-Dreifuss Muscular Dystrophy type 1
    Emery-Dreifuss Muscular Dystrophy type 2
    Limb Girdle Muscular Dystrophy type 1B
    Limb Girdle Muscular Dystrophy type 1C
    Limb Girdle Muscular Dystrophy type 1F
    Limb Girdle Muscular Dystrophy type 2A
    Limb Girdle Muscular Dystrophy type 2B
    Limb Girdle Muscular Dystrophy type 2C
    Limb Girdle Muscular Dystrophy type 2D
    Limb Girdle Muscular Dystrophy type 2E
    Limb Girdle Muscular Dystrophy type 2F
    Limb Girdle Muscular Dystrophy type 2I
    Limb Girdle Muscular Dystrophy type 2K
    Limb Girdle Muscular Dystrophy type 2N
    Congenital Muscular Dystrophy type 1A
    Congenital Muscular Dystrophy type 1C
    Congenital Muscular Dystrophy with rigid spine
    Congenital Muscular Dystrophy with integrin-alpha-7 deficiency
    Congenital Muscular Dystrophy, Ullrich type
    Bethlem myopathy
    Facio Scapulo Humeral Muscular Dystrophy type 1A
    Facio Scapulo Humeral Muscular Dystrophy type 2
    Section 2: Congenital Myopathies
    Congenital Multi-Mini-Core Myopathy
    Congenital Central-Core Myopathy with Malignant Hyperthermia
    Congenital Centronuclear Myopathy type 1
    Congenital Hyaline Body Myopathy
    Congenital Myotubular Myopathy
    Congenital Nemaline Myopathy type 2
    Congenital Fiber Type Disproportion type 1
    Congenital Fiber Type Disproportion
    Congenital Myofibrillar Myopathy type 1
    Congenital Myofibrillar Myopathy type 6
    Congenital Tubular Aggregate Myopathy
    Hereditary Inclusion Body Myopathy type 2
    Section 3: Ion Channel Disorders
    Myotonic Dystrophy type 1, Steinert Disease
    Congenital Myotonic Dystrophy
    Myotonic Dystrophy type 2, Proximal Myotonic Myopathy
    Congenital Myotonia, Thomsen Disease
    Hyperkalemic Periodic Paralysis
    Hypokalemic Periodic Paralysis type 1
    Slow-channel Congenital Myasthenic Syndrome
    Congenital Myasthenic Syndrome
    Brody Disease
    Section 4: Metabolic Myopathies
    Glycogenosis type 2, Pompe Disease
    Glycogenosis type 3, Cori-Forbes Disease
    Glycogenosis type 5, McArdle Disease
    Danon Disease
    Kearns-Sayre Syndrome
    Chronic Progressive External Ophthalmoplegia
    MELAS (Myopathy, Encephalopathy, Lactic Acidosis, Stroke-like)
    Leigh Syndrome due to COX Deficiency
    Mitochondrial Encephalopathy with COX Deficiency
    Coenzyme Q10 Deficiency
    Multiple Symmetrical Lipomatosis
    NARP (Neuropathy, Ataxia, Retinitis Pigmentosa)
    SANDO (Sensory Ataxic Neuropathy, Dysarthria, Ophthalmoparesis)
    Systemic Primary Carnitine Deficiency
    Neutral Lipid Storage Disease with Ichthyosis
    Neutral Lipid Storage Disease with Myopathy
    Multiple Acyl-CoA Dehydrogenase Deficiency
    Carnitine-Palmitoyl-Transferase-II Deficiency
    Niemann-Pick Disease type C1
    Section 5: Neurogenic Disorders
    Spinal Muscular Atrophy type 1, Werdnig-Hoffmann Disease
    Spinal Muscular Atrophy type 2
    Spinal Muscular Atrophy type 3, Kugelberg-Welander Disease
    Spinal Bulbar Muscular Atrophy, Kennedy Disease
    Charcot-Marie-Tooth Disease type 1A
    Charcot-Marie-Tooth Disease type 1B
    Charcot-Marie-Tooth Disease neuronal type
    Charcot-Marie-Tooth Disease type 4A
    Charcot-Marie-Tooth Disease with pyramidal features
    Charcot-Marie-Tooth Disease type X1
    Distal Spinal Muscular Atrophy
    Hereditary Neuropathy with Pressure Palsies
    Friedreich Ataxia
    Spastic Ataxia, Charlevoix-Saguenay type
    Ataxia-Telangiectasia, Louis-Bar Syndrome
    Spastic Paraparesis type 4
    Spastic Paraparesis type 7
    Optic Atrophy Plus Syndrome
    Amyotrophic Lateral Sclerosis type 1
    Amyotrophic Lateral Sclerosis.
    Digital Access Springer 2014
  • Digital
    Aga Syed Sameer, Mujeeb Zafar Banday, Saniya Nissar, editors.
    Summary: This book discusses the role of genetic polymorphism in susceptibility to cancers. The book explores the understanding of differences between the genetic polymorphisms and mutations.It reviews the mechanisms underlying the effect of polymorphism in genes encoding proteins that play an essential role in metabolism, signal transduction, cell cycle, and DNA repair mechanisms. Further, it investigates various techniques that are used for analyzing the genetic polymorphisms. The book contains many chapters which summarize the importance of genetic information obtained from polymorphism-based pharmaco-genetic tests to predict better drug response and life-threatening adverse reactions to chemotherapeutic agents, help in understanding of the impact of SNPs on gene function, and gives overview of the different SNP databases for examination. This book, therefore, serves as an essential guidebook for independent researchers as well as institutions working in this specialised field.

    Contents:
    Chapter 1. Polymorphisms and Mutation: What is difference?
    Chapter 2. Single nucleotide polymorphisms and pharmacogenomics
    Chapter 3. Impact of MicroRNA Polymorphisms on Breast Cancer Susceptibility
    Chapter 4. From inflammation to cancer: Role of genetic polymorphisms of Inflammatory Pathway Molecules in Gastric Cancer
    Chapter 5. Colorectal Cancer and genetic polymorphism in key regulatory low penetrance genes
    Chapter 6. Role of Genetic Polymorphisms in Breast Cancer
    Chapter 7. Genetic Polymorphisms of Essential Immune Pathogenic Response Genes and Risk of Cervical Cancer
    Chapter 8. Thyroid Cancer and genetic polymorphism
    Chapter 9. SNPs of TLRs and Bladder Cancer
    Chapter 10. Role of genetic polymorphisms in Lung Cancer.
    Digital Access Springer 2021
  • Print
    Terman, Lewis Madison.
    Contents:
    v. 1. Mental and physical traits of a thousand gifted children / L.M. Terman, assisted by B.T. Baldwin, and others
    v. 2. The early mental traits of three hundred geniuses / C.M. Cox, assisted by L.O. Gillan and others
    v. 3. The promise of youth; follow-up studies of a thousand gifted children / B.S. Burks and others
    v. 4. The gifted child grows up; twenty-five years' follow-up of a superior group / L.M. Terman and M.H. Oden
    v. 5. The gifted group at mid-life; thirty-five years' follow-up of the superior child / L.M. Terman and M.H. Oden.
    Print Access Request
    Location
    Version
    Call Number
    Items
    Stored offsite. Please request print.
    P499 .G32
    6
  • Digital
    P.B. Kavi Kishor, Manchikatla Venkat Rajam, T. Pullaiah, editors.
    Summary: Genetic transformation is a key technology, in which genes are transferred from one organism to another in order to improve agronomic traits and ultimately help humans. However, there is apprehension in some quarters that genetically modified crops may disturb the ecosystem. A number of non-governmental organizations continue to protest against GM crops and foods, despite the fact that many organisms are genetically modified naturally in the course of evolution. In this context, there is a need to educate the public about the importance of GM crops in terms of food and nutritional security. This book provides an overview of various crop plants where genetic transformation has been successfully implemented to improve their agronomically useful traits. It includes information on the gene(s) transferred, the method of gene transfer and the beneficial effects of these gene transfers and agronomic improvements compared to the wild plants. Further, it discusses the commercial prospects of these GM crops as well as the associated challenges. Given its scope, this book is a valuable resource for agricultural and horticultural scientists/experts wanting to explain to the public, politicians and non-governmental organizations the details of GM crops and how they can improve crops and the lives of farmers.

    Contents:
    Chapter 1.Genetic tinkering of crops for sustainable development - 2020 and Beyond
    Chapter 2.Genetic improvement of rice for food and nutritional security 3.Improvement of wheat (Triticum spp.) through gene manipulation
    Chapter 4. Transgenic finger millet [Eleusine coracana (L.) Gaertn.] for crop improvement
    Chapter 5. Transgenic pigeon pea [Cajanus cajan (L). Millsp.]
    Chapter 6. Genetically engineered chickpea: Potential of an orphan legume to achieve food and nutritional security by 2050
    Chapter 7. Progress in genetic engineering of cowpea for insect pest and virus resistance
    Chapter 8. Peanut (Arachis hypogaea L.) transgenic plants for abiotic stress tolerance
    Chapter 9. Genetic engineering of sunflower (Helianthus annuus L.) for important agronomic traits
    Chapter 10. Genetic engineering in safflower (Carthamus tinctorius L.): Retrospect and prospect
    Chapter 11. Nutritional value, in vitro regeneration and development of transgenic Cucurbita pepo and C. maxima for stress tolerance: An overview
    Chapter 12. Sugarcane transgenics: Developments and opportunities .
    Digital Access Springer 2021
  • Digital
    P.B. Kavi Kishor, Manchikatla Venkat Rajam, T. Pullaiah, editors.
    Summary: Genetic transformation is a key technology, in which genes are transferred from one organism to another in order to improve agronomic traits and ultimately help humans. However, there is concern in some quarters that genetically modified crops may disturb the ecosystem. A number of non-governmental organizations continue to protest against GM crops and foods, despite the fact that many organisms are genetically modified naturally in the course of evolution. In this context, there is a need to educate the public about the importance of GM crops in terms of food and nutritional security. This book provides an overview of various crop plants where genetic transformation has been successfully implemented to improve their agronomically useful traits. It includes information on the gene(s) transferred, the method of gene transfer and the beneficial effects of these gene transfers and the agronomic improvements compared to the wild plants. Further, it discusses the commercial prospects of these GM crops as well as the associated challenges. Given its scope, this book is a valuable resource for agricultural and horticultural scientists/experts wanting to explain to the public, politicians and non-governmental organizations the details of GM crops and how they can improve crops and the lives of farmers. It also appeals to researchers and postgraduate students. This volume focuses on the transgenics of mungbean, cowpea, chickpea, cotton, mulberrry, Jatropha, fingermillet, papaya, citrus plants and cassava. It also discusses CRISPR edited lines. .

    Contents:
    Chapter 1. Transgenic tomatoes for abiotic stress tolerance and fruit traits: A review of progress and a preview of potential
    Chapter 2.Genetically modified brinjal (Solanum melongena L.) and Beyond
    Chapter 3. Biotechnology of red pepper
    Chapter 4. Non-host armor against insect: Characterization and application of Capsicum annuum protease inhibitors in developing insect tolerant plants
    Chapter 5. Transgenic banana: Current status, opportunities and challenges
    Chapter 6. Transgenic papaya
    Melaine Randle and Paula Tennant
    Chapter 7. Genetically modified citrus: Current status, prospects and future challenges
    Chapter 8. Genetically modified cassava; the last hope that could help to feed the world: Recent advances
    Chapter 9. Transgenics for targeted trait manipulation: The current status of genetically engineered mulberry crop
    Chapter 10. Genetically engineered Jatropha: A new bioenergy crop
    Chapter 11. GM crops for plant virus resistance: A review.
    Digital Access Springer 2021
  • Digital
    Kenro Kusumi, Sally L. Dunwoodie, editors.
    Summary: Recent genetic studies of the spine has enhanced the understanding the genetic etiology of idiopathic, neuromuscular, and congenital forms of scoliosis. These findings are discussed in this timely review of scoliosis and developmental studies of the spine.

    Contents:
    Intro; Dedication; Preface; Contents; Contributors;
    Chapter 1: Developmental andFunctional Anatomy oftheSpine; Introduction; Embryonic Origins oftheSpine; Establishing theIntersomitic Boundary; Somite Epithelialization; Rostral/Caudal Polarity ofSomites; The Anatomy andDevelopment oftheVertebrae andIntervertebral Discs; Functional Anatomy oftheVertebrae andIV Discs; Development oftheVertebrae; Rostral/Caudal Patterning; Formation oftheIV Discs; The Anatomy andDevelopment ofSpinal Muscles; Functional Anatomy oftheSpinal Muscles; Development ofSpinal Muscles. Nongenetically Linked Conditions Characterized byAxial Skeletal DefectsSpina Bifida; The VATER Association; Environmental Factors That Cause Axial Skeletal Dysmorphogenesis; Valproic Acid; Hypoxia; Carbon Monoxide; Diabetes; Retinoic Acid; Hyperthermia; Arsenic; Ethanol; Methanol; Conclusion; References;
    Chapter 3: Congenital Scoliosis andSegmentation Defects oftheVertebrae intheGenetic Clinic; Introduction; Spondylocostal Dysostosis, Somitogenesis, andtheNotch Signalling Pathway; Varied Use ofClinical Terminology; Spondylocostal Dysostosis; Klippel-Feil Syndrome. Syndromes Containing CS PhenotypeAlagille Syndrome; VACTERL Association; Congenital NAD Deficiency Disorders; Facio-Auriculo-Vertebral Spectrum; Perspective; References;
    Chapter 5: Animal Models ofIdiopathic Scoliosis; Introduction; Normal Spine Function Requires theIntegration ofMultiple Musculoskeletal Tissues; Spine Form Follows Dysfunction; What Makes aGood Animal Model ofDisease?; Animal Models; Mechanical Models ofIS; Environmental Models; Genetic/Heritable Models ofIS; Aquatic Models ofIS; Mouse Models; Distinct Elements oftheMammalian Spine. Tendon DevelopmentSummary; References;
    Chapter 2: Environmental Factors andAxial Skeletal Dysmorphogenesis; Introduction; Vertebral Dysmorphogenesis inHuman Congenital Scoliosis; Normal Development oftheAxial Skeleton; Experimental Axial Skeletal Teratology; Pathogenesis ofAbnormal Axial Development; Overview ofAgents andConditions Associated withAxial Skeletal Teratogenesis; Recreational Teratogens; Pharmaceutical Teratogens; Industrial andEnvironmental Teratogens; Agricultural Teratogens; Infectious Diseases; Metabolic Conditions. The Genetics andClinical Description ofSCD SubtypesSCD1; SCD2; STD: Spondylothoracic Dysostosis; SCD3; SCD4; SCD5: Autosomal Dominant; SCD6; TBX6, Congenital Scoliosis, andMURCS; A New Classification andRadiological Reporting System forSDV; References;
    Chapter 4: The Genetics Contributing toDisorders Involving Congenital Scoliosis; Introduction; Background; Embryological Basis ofCS; Approaches inUnderstanding theGenetic Etiology ofCS; TBX6 Variants Contributing toCS; Syndromes andDisorders Associated withVMs; Spondylocostal Dysostosis; Klippel-Feil Syndrome.
    Digital Access Springer 2018
  • Digital
    [edited by] Michel Tibayrenc.
    Contents:
    Recent developments in the definition and official names of virus species / M.H.V. Van Regenmortel
    A theory-based pragmatism for discovering and classifying newly divergent species of bacterial pathogens / F.M. Cohan, Sarah Kopac
    Population structure of pathogenic bacteria / C.P. Andam, L. Challagundla, T. Azarian, W.P. Hanage, D.A. Robinson
    Epidemiology and evolution of fungal pathogens in plants / P. Gladieux, E.J. Byrnes III, G. Aguileta, M. Fisher, R.B. Billmyre, J. Heitman, T. Giraud
    Clonal evolution / T. de Meeûs, F. Prugnolle
    Coevolution of host and pathogen / A.D. Morgan, B. Koskella
    Microbes as tracers of past human demography and migrations / J.-P. Rasigade, A. Gilabert, T. Wirth
    Phylogenetic analysis of pathogens / D.A. Morrison
    Evolutionary responses of infectous diseases / G. Cochran, H. Harpending
    Infectous disease genomics / Y.-T. Liu
    Proteomics and host-pathogen interactions / D.G. Biron, D. Nedelkov, D. Missé, P. Holzmuller
    The evolution of antibiotic resistance / F. González-Candelas, I. Comas, J.L. Martinez, J.C. Galán, F. Baquero
    Modern morphometrics of medically important anthropods / J.-P. Dujardin
    Evolution of resistance to insecticide in disease vectors / P. Labbé, J.-P. David, H. Alout, P. Milesi, L. Djogbénou, N. Pasteur, M. Weill
    Genetics of major insect vectors / P.L. Dorn, S. Justi, E.S. Krasfur, G.C. Lanzaro, A.J. Cornel, Y. Lee, C.A. Hill
    Multilocus sequence typing of pathogens / M. Pérez-Losada, M. Arenas, E. Castro-Nallar
    Next-generation sequencing, bioinformatics, and infectous diseases / R. van Aerle, M. van der Giezen
    Genomics of infectous diseases and private industry / G. Vernet
    Current progress in the pharmacogenetics of infectous disease tehrapy / E. Elliot, T. Mahungu, A. Owen
    Genetic exchange in trypanosomatids and its relevance to epidemiology / W. Gibson, M.D. Lewis, M. Yeo, M.A. Miles
    Genomic insights into the past, current, and future evolution of human parasites of the genus plasmodium / C.J. Sutherland, S.D. Polley
    Integrated genetic epidemiology of chagas disease / M. Tibayrenc, M.A. Shaw
    Adaptive evolution of the mycobacterium tuberculosis complex to different hosts / E. Broset, J. Gonzalo-Asensio
    The evolution and dynamics of methicillin-resistant staphylococcus aureus / M.M.H. Adelbary, P. Basset, D.S. Blanc, E.J. Feil
    Origin and emergence of HIV/AIDS / M. D'arc, L. Etienne, E. Delaporte, M. Peeters
    Evolution of SARS coronavirus and the relevance of modern molecular epidemiology / Z. Shi, L.-F. Wang
    Ecology and evolution of avian influenza viruses / A.C. Hurt, R.A.M. Fouchier, D. Vijaykrishna.
    Digital Access ScienceDirect 2017
  • Digital/Print
    Tom Strachan, Judith Goodship, Patrick Chinnery.
    Summary: "Genetics and Genomics in Medicine is a new textbook written for undergraduate and graduate students, as well as medical researchers, which explains the science behind the uses of genetics and genomics in medicine today. It is not just about rare inherited and chromosomal disorders, but how genetics affects the whole spectrum of human health and disease. DNA technologies are explained, with emphasis on the modern techniques that have revolutionized the use of genetic information in medicine and are indicating the role of genetics in common complex diseases. The detailed, integrative coverage of genetic approaches to treatment and prevention includes pharmacogenomics and the prospects for personalized medicine. Cancers are essentially genetic diseases and are given a dedicated chapter that includes new insights from cancer genome sequencing. Clinical disorders are covered throughout and there are extensive end-of-chapter questions and problems"--Provided by publisher.
    Limited to 3 simultaneous users
    Print Access Request
    Location
    Version
    Call Number
    Items
    Books: General Collection (Downstairs)
    RB155.5 .S77 2014
    1
  • Digital
    Tom Strachan and Anneke Lucassen.
    Limited to 3 simultaneous users
  • Digital
    Christopher A. Cullis, editor.
    Summary: Linum (flax) is a genus of about 200 species in the flowering plant family Linaceae. The genus includes common flax, which is one of the best fibers to produce linen, the seeds to produce linseed oil and has health-related properties of flax in human and animal nutrition. This book describes the genetics and genomics of Linum including the development of extensive experimental resources (e.g. whole genome sequence, efficient transformation methods, insertional mutant collections, large germplasm collections, resequenced genomes) that have led much progress and its economic importance. The methods and use of Linum to address a wide range of applications (e.g. disease resistance, cell wall composition, abiotic stress tolerance, floral development, natural diversity) is also discussed.

    Contents:
    Table of Contents (DRAFT) Preface 1. Taxonomy and Natural History of Linum Possible Authors: Axel Diederichsen and/or Yong Bi Fu 2. The gene pool of Linum usitatissimum and immediate progenitor Linum bienne Possible Authors: Axel Diederichsen and/or Yong Bi Fu (Flax variety descriptors Possible authors: L. Maggioni and/or M. Pavelek) 3. Flax breeding and variety release Possible Authors: Scott Duguid & /or Helen Booker 4. The flax genome sequence: a core resource for flax genomics Possible Author: Michael Deyholos<5. The assembly of the flax genomes into chromosomes Authors: Frank You & Sylvie Cloutier 6. Comparisons between oil-seed and fiber flax genomes Author: C. Cullis 7. The Linum transcriptome Possible author: R Datla 8. Mapping resources
    molecular markers, mapping populations Possible author: S. Cloutier 9. Flax transposable elements Possible author(s): L. Galindo and M Deyholos 10. Flax small RNAs Possible author(s): T.Y Moss and C. Cullis 11. Gene mutagenesis systems in the fatty acid pathway Possible Authors: Alan Green for fatty acid mutants 12. Gene mutagenesis systems and resources for the flax
    TILLING, transposons Possible Authors: M. Deyholos 13. QTL mapping Possible Authors: S. Cloutier 14. Flax cell walls and fiber Possible Authors: N. Carpita or M. Deyholos/Luca Comai 15. Flax transformation Authors: N. Bastaki and C Cullis 16. Linum Bioinformatics Resources Author: Deyholos and Cloutier 17. Flax disease resistance genes Possible author: Jeff Ellis 18. Genomic and phenotypic responses of flax to stress Author: C. Cullis 19. Flax secondary products Author: Selvaraj 20. Flax cyclic peptides Author: Datla 21. Medicinal uses of flax Possible author: Stephanie P.B. Caligiuri Author: Datla 22. Transgenic flax and the Triffid affair Possible author: J. Smyth 22. Fundamental insights into plant biology that might be offered by Linum Author: C. Cullis Index.
    Digital Access Springer 2019
  • Digital
    volume editors Michael Posthumus, Malcolm Collins.
    Contents:
    Core concepts in human genetics : understanding the complex phenotype of sport performance and susceptibility to sport injury / Gibson, W.T
    Nature versus nurture in determining athletic ability / Yan, X., Papadimitriou, I., Lidor, R., Eynon, N
    Recent research in the genetics of exercise training adaptation / Venezia, A.C., Roth, S.M
    Genes and athletic performance : an update / Ahmetov, I.I., Egorova, E.S., Gabdrakhmanova, L.J., Fedotovskaya, O.N
    The future of genomic research in athletic performance and adaptation to training / Wang, G., Tanaka, M., Eynon, N., North, K.N., Williams, A.G., Collins, M., Moran, C.N., Britton, S.L., Fuku, N., Ashley, E.A., Klissouras, V., Lucia, A., Ahmetov, I.I., de Geus, E., Alsayrafi, M., Pitsiladis, Y.P
    Genetics of musculoskeletal exercise-related phenotypes / Collins, M., O'Connell, K., Posthumus, M
    Genes and musculoskeletal soft-tissue injuries / Rahim, M., Collins, M., September, A
    Genetic testing for sports performance, responses to training and injury risk : practical and ethical considerations / Williams, A.G., Wackerhage, H., Day, S.H.
    Digital Access Karger 2016
  • Digital
    volume editors, Anna L. Gloyn, Oxford, Mark I. McCarthy, Oxford.
    Contents:
    Genome-wide association studies in type 2 diabetes / Beer, N.L.; McCarthy, M.I.
    Fine mapping type 2 diabetes susceptibility loci / Morris, A.P.
    Whole genome and exome sequencing of type 2 diabetes / Gaulton, K.; Flannick, J.; Fuchsberger, C.
    Genome-wide association studies of glycaemic traits : a magical journey / Florez, J.C.; Barroso, I.
    Genome-wide association studies of obesity and related traits / Mohlke, K.L.; Lindgren, C.M.
    Next-generation sequencing for the diagnosis of monogenic diabetes and discovery of novel aetiologies / Ellard, S.; De Franco, E.
    Whole-exome sequencing of patients with severe disorders of insulin action / Semple, R.; Barroso, I.
    Epigenetic modifications and type 2 diabetes in humans / Ling, C.
    Insights into ?-cell biology and type 2 diabetes pathogenesis from studies of the islet transcriptome / van de Bunt, M.; Morán, I.; FerrerJ.; McCarthy, M.I.
    Genomics of adipose tissue / Pinnick, K.E.; Karpe, F.
    Translating genetic association signals for diabetes and metabolic traits into molecular mechanisms for disease / Rees, M.G.; Gloyn, A.L.
    Understanding molecular mechanisms for diabetes and obesity through mouse models / Merkestein, M.; Cox, R.; Ashcroft, F.
    Genetics of drug response in diabetes / Pearson, E.R.; Florez, J.C.
    Translating advances in our understanding of the genetics of diabetes into the clinic / Gardner, D.S.; Owen, K.R.; Gloyn, A.L.
    Digital Access Karger 2014
  • Digital
    edited by Muntaser Ibrahim, Charles Rotimi.
    Summary: "The birthplace of modern humans, Africa, has the highest genetic diversity in the world, yet it remains vastly understudied. With biomedical research increasingly focused on human variation, studying the large population size and number of mutations in African genomes could unravel the complexity of phenotypic traits underlying the biology of our species and hold huge potential for scientific and medical advances. An initial chapter 'conceptualizes Africa', providing relevant terminology. The first section covers genetic history and population structure. The next section looks at the genetic basis of common infectious diseases, such as leishmaniasis, malaria and tuberculosis, with a final part considering common non-communicable diseases, such as diabetes, hypertension, obesity, heart disease and cancer. Gene environment interaction under globalization and the burden of diseases of lifestyle are included. For researchers and graduate students in biological anthropology, genetic anthropology, human and population genetics, and public health"--Provided by publisher.

    Contents:
    1 Reflections on Conceptualizing Africa for Biological Studies with a Historical Component: A Small Essay
    1.1 Prolegomenon
    1.2 ''Blackness'' and Notions of Africa
    1.3 Raciotypological Thinking
    1.4 Africa: Evolution and Peopling
    1.5 Human Variation in Africa
    1.6 Defining versus Describing Africa/Africans
    1.7 Biological Variation and Social Organization
    1.8 Summary
    Acknowledgments
    References --2 History and Genetics in Africa: Multidisciplinary Efforts
    2.1 Introduction
    2.2 Genetics and Bantu Speakers
    2.3 Genes, Food Production, and Afrasan
    2.4 Genes, Ethno-Population Origins, and Identity
    2.5 Genetics and the Northern Nile Valley: Egypt
    2.6 The Case of the Nilotes/Nilotics: Considerations for Population History
    2.7 Brief Discussion and Conclusions
    Acknowledgments
    References 3 Disease, Selection, and Evolution in the African Landscape
    3.1 The Peculiarity of Genetic Structure In and Out of Africa
    3.2 Population Structure Drift and Culture3.3 Food Culture and Genetic Variation
    3.4 Inbreeding
    3.5 Natural Selection and Disease
    3.6 Biological Network and Genetic Borrowing
    3.7 Epigenetics, an Added Layer of Complexity in the Selection Plateau
    References
    4 Genetic Susceptibility to Visceral Leishmaniasis
    4.1 Leishmaniasis
    4.2 Genetic Susceptibility to Visceral Leishmaniasis
    4.3 Candidate Gene Studies
    4.3.1 SLC11A1 (Formerly NRAMP1)
    HLA as a Candidate Gene Region
    Chromosome 17q11.1-q12
    Chromosome 5q31-q33
    4.3.2 IFNG and IFNGR1
    4.3.3 IL2RB and IL1B
    4.3.4 CXCR1 and CXCR2
    4.4 Genome-Wide Linkage Studies
    4.5 Genome Wide Association Studies
    4.6 Conclusion and Future Perspectives
    References 5 Genetics of Infection in Sub-Saharan Africa: What Can the Study of Mendelian Immunodeficiency Disorders Contribute?
    5.1 Introduction: The Burden of Infectious Diseases in African Populations
    5.2 Genetic Susceptibility to Infectious Diseases: Historical Perspectives
    5.3 More Recent Approaches to Mapping TB Susceptibility Genes: What Have We Learned from Monogenic Disorders?
    5.4 Molecular Basis of Mendelian Susceptibility to Mycobacterial Disease in Humans
    5.4.1 Resistance to infection conferred by single-gene defects at the population level and the role of natural selection
    5.5 Future Directions
    References
    6 Pharmacogenomics and Infectious Diseases in Africa: An Evolutionary Perspective
    6.1 Introduction
    6.2 The Burden of Infectious Diseases in Africa
    6.2.1 Malaria
    6.2.2 Human African Trypanosomiasis
    6.2.3 Human Immunodeficiency Virus
    6.2.4 Lassa Fever
    6.2.5 Tuberculosis
    6.3 Traditional Herbal Medicine
    6.4 Progressing Toward Genomic Medicine in Africa
    6.5 Conclusion
    Acknowledgments
    References
    Digital Access Cambridge 2019
  • Digital
    volume editors, Barbara Vona, Thomas Haaf.
    Contents:
    Genetics and deafness : a view from the inside / Blankmeyer Burke, T. Snoddon, K., Wilkinson, E.
    Hearing loss in older age and its effect on the individuals, their families, and the community / McMahon, C.M
    Audiological assessment and management in the era of precision medicine / Munro, K.J., Newton, V.E., Moore, D.R
    Next-generation newborn hearing screening / Shen, J., Morton, C.C
    Clinical challenges in diagnosing the genetic etiology of hearing loss / Birkeland, A.C., Lesperance, M.M.
    Genetic elucidation of nonsyndromic hearing loss in the high-throughput sequencing era / Vona, B., Hofrichter, M.A.H., Chioza, B.A., Crosby, A.H., Nanda, I., Haaf, T.
    Genetic modifiers of hearing loss / Yousaf, R., Friedman, T.B., Riazuddin, S.
    Genetics of age-related hearing loss / Dawes, P., Payton, A.
    Genetic modifiers of hearing loss in mice : the case of phenotypic modification in homozygous cdh23ahl age-related hearing loss / Kikkawa, Y., Miyasaka, Y.
    Using zebrafish to study human deafness and hearing regeneration / Varshney, G.K., Pei, W., Burgess, S.M.
    Current understanding and potential of gene therapy for hearing restoration in humans / Akil, O., Lustig, L.
    Digital Access Karger 2016
  • Digital
    Peter Igaz, Attila Patócs, editors.
    Summary: This book provides a comprehensive overview of the genetic basis underlying endocrine diseases. It covers both the molecular and clinical consequences of these genetic defects, as well as the relevance for clinical care, highlighting issues of genetic counseling. Several endocrine diseases have a genetic background, and contemporary research in the field plays a crucial role in the clinical care of endocrine diseases. In recent years, there have been major developments in our understanding of the genetic basis of endocrine diseases. Several novel genes and mutations predisposing individuals to monogenic endocrine diseases have been discovered, and with the advent of next generation sequencing, a huge amount of new data has become available. Further, novel molecular mechanisms, such as genomic imprinting, have been implicated in the pathogenesis of endocrine diseases. A better understanding of the genetic background of these diseases is relevant not only from the research perspective, but also in terms of clinical care. As such, this book is an essential read for both researchers and clinicians working in the field.

    Contents:
    Intro; Preface; Contents; Editors and Contributors; List of the Most Commonly Used Abbreviations; Part I: Basics of Genetics;
    Chapter 1: Basic Concepts of Genetics; 1.1 Introduction; 1.2 Basic Terms of Genetics; 1.3 Mutations; 1.4 Chromosomes; 1.5 Proto-oncogenes and Tumor Suppressors; 1.6 DNA Variations; 1.7 Epigenetics; References;
    Chapter 2: Brief Description of Inheritance Patterns; 2.1 Introduction; 2.2 Autosomal Dominant Inheritance; 2.3 Autosomal Recessive Inheritance; 2.4 X-Linked Dominant Inheritance; 2.5 X-Linked Recessive Inheritance; 2.6 Conclusions; References 6.3 The Glucocorticoid Signaling Pathway; 6.4 Primary Generalized Glucocorticoid Resistance (PGGR) or "Chrousos Syndrom"; 6.5 Beyond NR3C1 Genetic Defects; 6.6 NR3C1 Polymorphisms; 6.7 Concluding Remarks; References; Part III: Endocrine Diseases Inherited as Monogenic Traits: Hereditary Diseases Predisposing to Endocrine Tumors;
    Chapter 7: Overview of Genetically Determined Diseases/Multiple Endocrine Neoplasia Syndromes Predisposing to Endocrine Tumors; 7.1 Introduction; 7.2 Multiple Endocrine Neoplasia Syndromes; 7.2.1 Multiple Endocrine Neoplasia Type 1
    Chapter 3: Family Screening and Genetic Counseling; References;
    Chapter 4: Brief Summary of the Most Important Molecular Genetic Methods (PCR, qPCR, Microarray, Next-Generation Sequencing, e ... ; 4.1 Introduction; 4.2 DNA Isolation and Quality Control; 4.3 Polymerase Chain Reaction (PCR); 4.4 Multiplex Ligation-Dependent Probe Amplification (MLPA); 4.5 Sanger Sequencing; 4.6 Array-Based Methods; 4.7 Next-Generation Sequencing; 4.8 Conclusion; References; Part II: Endocrine Diseases Inherited as Monogenic Traits: Hormone Resistance Syndromes.
    Digital Access Springer 2019
  • Digital
    edited by Ortrud K. Steinlein.
    Digital Access ScienceDirect 2014
  • Digital
    Chitra Kannabiran.
    Summary: This book provides comprehensive information on the genetics of eye diseases affecting various parts of the eye, and addresses a range of genetic etiologies. These diseases include several hereditary disorders of anterior and posterior segment, and with different genetic etiologies. The genetics of eye diseases is a field that has been rapidly growing over the last two decades, and comprises a vast area with considerable clinical and genetic heterogeneity. The main goal of this work is to discuss the status quo of genetics for each of the disorders covered, and to highlight unusual or atypical patterns of inheritance and genetic associations. For each relevant gene, it describes the pathogenic associations and variants, genotype-phenotype correlations, and functions at the cellular and molecular level. Genetics of Eye Diseases offers a valuable reference guide for geneticists and clinicians alike, while also providing a comprehensive overview of the field for graduate and doctoral-level students. In addition to sharing essential information on the genetics of each disease, it highlights recent advances that are representative of the developments in the field as a whole.
    Digital Access Springer 2019
  • Digital
    volume editor, Peter Vogt.
    Contents:
    Genetic basis of male and female infertility / R. Mallepaly, P.R. Butler, A.S. Herati, D.J. Lamb
    Genetics of premature ovarian failure : new developments in etiology opportunity / Y. Qin, J.L. Simpson, Z.-J. Chen
    Genetics of Klinefelter syndrome : experimental exploration / J. Wistuba, C. Brand, M. Zitzmann, O.S. Damm
    Human Y chromosome and male infertility : forward and back from azoospermia factor chromatin structure to azoospermia factor gene function / P.H. Vogt, U. Bender, J. Zimmer, T. Strowitzki
    Genetics and pathophysiology of the cystic fibrosis transmembrane conductance regulator in male reproduction : new evidence of a direct effect on the male germline / A. Touré
    The genetics of androgen receptor signalling in male fertility / L. O'Hara, L.B. Smith
    The genetics of postmeiotic male germ cell differentiation from round spermatids to mature sperm / T. Lehtiniemi, N. Kotaja
    The epigenetics of sperm chromatin / M.B. Shamsi, L. Simon, D.T. Carrell
    Characteristic features of male germline development in primates / R. Behr
    Genetic and epigenetic mouse models of human male infertility / M. Godmann, S. Zemter, C. Kosan
    In vitro spermatogenesis and its potential clinical implication for patients / J.-B. Stukenborg, K. Jahnukainen.
    Digital Access Karger 2017
  • Digital
    edited by Mohamed Arafa, Haitham Elbardisi, Ahmad Majzoub, Ashok Agarwal.
    Summary: This unique, case-based guide provides a thoughtful and comprehensive overview of the genetic basis of male infertility for the practicing clinician. In addition to discussing the molecular foundations of sperm production and the consequences of genetic abnormalities on various stages of sperm development, it examines the clinical aspects of acknowledged genetic disorders and their implications on male fertility. In so doing, it offers the necessary tools required by the clinician for the diagnosis and treatment of infertile men with genetic abnormalities. Moreover, it provides essential algorithms that may aid in counseling patients in the clinic. The text is arranged in four thematic sections for easy reference. The genetic foundation of male reproduction is presented in part 1, including regulation of sperm production, the structure of sperm chromatin, and spermatogenesis. The impact of genetic abnormalities on male infertility is the subject of part 2, covering sperm defects, mitochondrial function and DNA fragmentation. The clinical case material in part 3 illustrates real-world examples of genetic etiologies and the current diagnostic and therapeutic strategies for conditions such as vas asplasia, cryptorchidism, immotile cilia syndrome, sperm aneuploidy and other challenging scenarios. Casting forward, the fourth and final section presents an overview of future possibilities for management of genetic causes of male infertility, including gene editing. Fully exploring the clinical context of these genetic conditions in a practical manner that appeals to the practicing clinician, Genetics of Male Infertility is an exciting and essential text for reproductive medicine specialists, andrologists, urologists, researchers and all other clinicians treating infertile patients.

    Contents:
    Part I: The Genetic Basis of Reproduction
    The Molecular Genetics of Testis Determination
    Molecular Regulation of Sperm Production Cascade
    Spermatozoal Chromatin Structure: Role in Sperm Functions and Fertilization
    Genetic Basis of Endocrine Regulation of Spermatogenesis
    Epidemiology of Genetic Disorders in Male Infertility
    Genetic Evaluation of Male Infertility
    Part II: Impact of Genetics on the Sperm Cell
    Genetic Basis of Sperm Morphologic Defects: Head Defects, Body and Tail Defects
    Mitochondrial Function and Male Infertility
    Sperm DNA Fragmentation and Male Infertility
    The Sperm Epigenome and Potential Implications for the Developing Embryo
    Part III: Clinical Case Scenarios
    Klinefelter Syndrome
    Chromosomal Translocations and Inversion in Male Infertility
    Genetics of Vas Aplasia
    Anomalies of the Y Chromosome
    Infertility and Cryptorchidism
    Kartagener and Immotile Cilia Syndrome
    Persistent Müllerian Duct Syndrome
    Disorders of Sex Determination
    Endocrine Genetic Defects
    Sperm Aneuploidy
    Part IV: Genetic Infertility: Is There Any Hope?- Sperm DNA Fragmentation
    The Potential of CRISPR/Cas Gene Editing to Correct Male Infertility.
    Digital Access Springer 2020
  • Digital
    Struan F.A. Grant, editor.
    Summary: In the past four years, many genetic loci have been implicated for BMI from the outcomes of genome-wide association studies (GWAS), primarily in adults. Insulin-induced gene 2 (INSIG2) was the first locus to be reported by this method to have a role in obesity, but replication attempts have yielded inconsistent outcomes. The identification of the second locus, the fat mass- and obesity-associated gene (FTO), has been more robustly observed by others. Studies from both FTO knock out and FTO over expression mouse model support the fact that FTO is directly involved in the regulation of energy intake and metabolism in mice, where the lack of FTO expression leads to leanness while enhanced expression of FTO leads to obesity. Along with numerous other studies, a number of genetic variants have been established robustly in the context of obesity, giving us fresh insights into the pathogenesis of the disease. This book provides a comprehensive overview of efforts aimed at uncovering genetic variants associated with obesity, which have been particularly successful in the past 5 years with the advent of genome-wide association studies (GWAS). The Genetics of Obesity covers this state of the art technology and its application to obesity in great detail. Topics include genetics of childhood obesity, genetics of syndromic obesity, copy number variants and extreme obesity, co-morbidities of obesity genetics, and functional follow-up of genetic variants.

    Contents:
    Genetic Variation and Obesity Prior to the Era of Genome-Wide Association Studies
    Genetic Obesity Syndromes
    Genome-Wide Association Studies of Obesity
    Copy Number Variants and their Contribution to the Risk of Obesity
    Genetics of Childhood Obesity
    Genetic Pleiotropies of Obesity
    Functional Follow-up of Genetic Variants Using FTO as the Prime Example.
    Digital Access Springer 2014
  • Digital
    H. V. Nema, Nitin Nema, editors.
    Summary: The book focuses on describing the importance of genetics in eye diseases in a comprehensive and concise manner. Mutations in different set of genes have been detected and incriminated in complex mechanisms of causing leading eye diseases such as cataract and glaucoma. This book written by well-established ophthalmologists and geneticists presents a complicated subject in simple and easy to understand manner. Chapters cover the concept of gene therapy which is an emerging subject with high potential. The book includes a separate chapter on genetic counseling, which has become an integral component of ophthalmology. The book will assist the practicing ophthalmologists in early diagnosis of genetic eye diseases as well as help the geneticists in understaning the basic concepts. It will also be useful for students who are preparing for MD, MS, DNB and FRCS examinations.

    Contents:
    A perspective of genes and genetics in ophthalmology
    Genetics of corneal dystrophies
    Genetics of keratoconus
    Genetics of cataract
    Genetics of congenital glaucoma
    Genetics of glaucoma
    Genetics of retinoblastoma
    Genetics of RP
    Genetics of AMD
    Genetics of high myopia
    Genetics of ROP
    Gene therapy in DR
    Genetics of RD
    Genetics of strabismus
    Genetics of dry eye disease
    Genetic counseling.
    Digital Access Springer 2022
  • Digital
    Javier Martín, Francisco David Carmona, editor.
    Summary: The main aim of this volume is to provide an updated overview of the genetic basis of a group of complex disorders that are considered rare individually, but show a relatively high prevalence on the whole in developed countries: the rare autoimmune diseases. These are chronic disorders that involve long and expensive treatments with considerable side effects that may dramatically reduce the quality of life of affected people. Therefore, shedding light into their pathologic mechanisms is a major concern given their growing social and economic awareness and impact. General sections include different chapters on single entities as systemic lupus and sclerosis, Behçets disease, Sjogrens syndrome and polymiositis, and sections devoted to autoimmune vasculitis, hepatic autoimmune conditions, as well as those affecting the nervous system, and a concluding chapter in which the shared predisposition amongst all diseases is discussed. All the chapters are given a homogeneous scheme in which the authors explain the clinical singularities of every disease and report the recent breakthrough discoveries related to them, giving a critical interpretation and suggesting future perspectives. All contributors are renowned researchers with high expertise in each disease. Due to the exponential increase in our understanding of the genetic causes of these complex diseases, a major advance in biomedical discovery is taking place. However, most of the achievements in this field are very recent and there is a lack of bibliography gathering them together. This book is thus filling a gap and will prove a useful companion to clinicians in the first place (internists, rheumatologists, clinical immunologists, and hematologists) but also to basic and applied researchers.

    Contents:
    Preface
    I Connective tissue diseases
    1 Systemic lupus erythematosus (Possible contributors: Maria Teruel & Marta Alarcón)
    2 Systemic sclerosis (Possible contributors: Elena Lopez-Isac & Marialbert Acosta)
    3 Behçets disease (Possible contributors: Lourdes Ortiz & Francisca Gonzalez-Ecribano)
    4 Sjogren's síndrome (Possible contributors: Pers JO, Renaudineau Y. & Xavier Marriet)
    5 Polymiositis/Dermatomyositis (Possible contributors: Ana Márquez & Albert Selva)
    II Autoimmune Vasculitis
    6 ANCA-associated Vasculitis (Possible contributors: Augusto Vaglio)
    7 Giant Cell Arteritis (Possible contributors: F. David Carmona & Miguel Ángel Gónzalez-Gay)
    8 Takayasus Arteritis (Possible contributors: Amr H. Sawalha)
    9 Kawasakis Disease (Possible contributors: David Burgner)
    III Gastrointestinal and Liver/hepatic Autoimmune Conditions
    10 Primary Biliary Cirrhosis, Sclerosing Cholangitis, and Autoimmune Hepatitis (Possible contributors: G.J. Webb & G.M. Hirschfield)
    IV Central and Peripheral Nervous System
    11 Multiple Sclerosis (Possible contributors: Antonio Alcina & Fuencisla Matesanz)
    12 Myastenia Gravis (Possible contributors: Güher Saruhan Direskeneli)
    V Shared Gentetic Component
    13 Common Genetic Component in Autoimmunity (Possible contributors: Alexandra Sasha)
    Subject Index.
    Digital Access Springer 2019
  • Digital
    Michael M. Vanyukov, editor.
    Summary: The book illuminates the complex problems in genetic studies of substance use and addiction. It provides a comprehensive overview that fills the gap in the literature and points out future directions. The book includes three sections that apply to any complex traits and disorders, particularly psychological and psychiatric. The first section covers the traits and phenotypes that are the target of genetic research in substance use and addiction. Following this, the second section analyzes the methods and results of biometric genetic studies in this area. The third section reviews research in gene mapping and epigenetics. Genetics of Substance Use is a first-of-its-kind monograph that presents contemporary solutions and methods for a wide range of researchers and practitioners across disciplines.

    Contents:
    Substance use phenotyping
    Substance use: disorders and continuous traits
    Neurobiological systems in substance use
    Psychological mechanisms of substance use
    Biometric genetic studies in substance use
    Twin studies
    Family and adoption studies
    Genomic studies in substance use
    Gene mapping in complex disorders
    Linkage and association studies
    Epigenomic studies
    Conclusions.
    Digital Access Springer 2022
  • Digital
    Libby Edwards, Peter J. Lynch.
    Contents:
    Genital anatomy / Libby Edwards
    Terminology and classification of genital disorders / Peter J Lynch
    General principles of diagnosis and therapy / Peter J Lynch
    Diagnostic and therapeutic procedures / Libby Edwards
    Skin colored lesions / Peter J. Lynch
    Red lesions: patches and plaques / Peter J Lynch, Libby Edwards
    Red papules and nodules / Peter J. Lynch
    White lesions / Libby Edwards
    Dark colored lesions : brown, blue, gray or black disorders / Peter J. Lynch
    Blistering and pustular diseases / Libby Edwards
    Erosions and ulcers / Libby Edwards, Peter J. Lynch
    Edema / Peter J. Lynch
    Pruritus / Peter J. Lynch
    Pediatric genital disease / Libby Edwards
    Vaginitis and balanitis / Libby Edwards
    Special issues in genital dermatology, psychosexual aspects, immunosuppression, and aging / Peter J. Lynch, Libby Edwards.
    Digital Access Ovid 2018
  • Digital/Print
    edited by David F. Paulson.
    Digital Access Springer 1982
    Print Access Request
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    Items
    Stored offsite. Please request print.
    RC280.G4 G47
    1
  • Digital/Print
    edited by Siamak Daneshmand, Kevin G. Chan.
    Summary: This book addresses the most pressing current questions in the management of urologic malignancies. Placing the rapid advances in imaging and molecular markers into a clinical context, it explains their effects on prognosis and treatment planning. Similarly, it carefully examines advances in immunotherapy, focusing in particular on the role of immune checkpoint inhibitors in both early- and late-stage urologic malignancies. Looking beyond the improvements in minimally invasive techniques for urologic cancers, it reviews the impacts of care coordination pathways and enhanced recovery after surgery protocols. Futher, the book includes an enlightening discussion of the decision algorithm for the treatment of early-stage, high-grade bladder cancer, taking into account evidence on the most advanced treatment options and the circumstances in which surgery may need to be expedited. The final two chapters are devoted to testicular cancer: the first discusses recent advances in prognostication, while the second elucidates contemporary medical and surgical management.

    Contents:
    New Imaging Techniques in Prostate Cancer
    Targeted ablative therapies for prostate cancer
    Prostate cancer markers
    Prognostic value of CTC's in urologic cancers
    Management of Small Renal Masses
    Advances in the Treatment of Metastatic Renal Cell Carcinoma.-Imaging in urologic cancers
    Molecular prognostication in Bladder cancer
    Early cystectomy for high risk non-muscle invasive disease
    Care-coordination pathway after radical cystectomy
    Current role of checkpoint inhibitors in urologic cancers
    ) The Cancer Genome Atlas Project
    Prognostic models in germ cell tumors
    Modern management of testicular cancer.
    Digital Access Springer 2018
    Print Access Request
    Location
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    Items
    Books: General Collection (Downstairs)
    RC280.G4 G465 2018
    1
  • Digital
    edited by Mukesh G. Harisinghani, Arumugam Rajesh.
    Summary: Covering all modalities currently used as well as emerging novel imaging tools, each chapter covers an aspect of Genitourinary Imaging with a comprehensive coverage of subspeciatlies. Genitourinary Imaging - A Case Based Approach closely mimics day to day clinical practice, and allows retention of pertinent practice information in an easy to understand format. Providing Genitourinary specific content in a portable form that can be used in close proximity to the PACS workstation, Genitourinary Imaging - A Case Based Approach is the perfect book for residents both in training and practicing as well as genitourinary radiologists worldwide.

    Contents:
    1. Adrenal Gland
    2. Kidneys
    3. Ureters
    4. Bladder and Urethra.-5. Retroperitoneum
    6. Female Pelvis
    7. Male Pelvis.
    Digital Access Springer 2015
  • Print
    Matthew S. Davenport, MD, Assistant Professor, Division of Abdominal Imaging, Department of Radiology, University of Michigan Health System, Ann Arbor, Michigan.
    Contents:
    Contrast media
    Kidneys (native and transplant)
    Adrenal glands
    Upper tract (pelvicalyceal system and ureter)
    Lower tract (bladder and urethra)
    Male genital (prostate, penis, scrotum)
    Female genital i (uterus and cervix)
    Female genital ii (ovary, fallopian tube, vagina, and vulva)
    Retroperitoneum
    Review and miscellaneous.
    Print Unavailable: Checked out Recall Item
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    Items
    Books: General Collection (Downstairs)
    RC874 .D38 2015
    1
  • Digital
    Ron Zagoria, Ray Dyer, Christopher Brady.
    Contents:
    An introduction to radiologic methods
    The kidney and retroperitoneum : anatomy and congenital abnormalities / Raymond Dyer
    Renal masses / Ronald Zagoria
    The kidney : the diffuse parenchymal abnormality / Raymond Dyer
    The renal sinus, pelvocalyceal system, and ureter / Ronald Zagoria
    The lower urinary tract / Christopher Brady
    The female genital tract / Christopher Brady
    The male genital tract / Raymond Dyer
    Imaging of the adrenal glands / Christopher Brady
    Interventional genitourinary radiology / Ronald Zagoria.
    Digital Access ClinicalKey 2016
  • Digital
    edited by Ming Zhou, Cristina Magi-Galluzzi.
    Contents:
    Nonneoplastic diseases of the prostate / Kiril Trpkov
    Neoplastic diseases of the prostate / Ming Zhou, Cristina Magi-Galluzzi
    Nonneoplastic diseases of the urinary bladder / Fang-Ming Deng, Jonathan Melamed
    Neoplasms of the urinary bladder / Jesse K. McKenney, Ming Zhou, Cristina Magi-Galluzzi
    Nonneoplastic diseases of the kidney / Stephen M. Bonsib
    Neoplasms of the kidney / Ming Zhou, Eyas M. Hattab, John N. Eble, Liang Cheng
    Introduction to renal biopsy / Laura Barisoni, Lois J. Arend, David B. Thomas
    Diseases of the ureter and renal pelvis / Ximing J. Yang
    Diseases of penis, urethra, and scrotum / Rajal B. Shah
    Nonneoplastic diseases of the testis / Cristina Magi-Galluzzi, Howard S. Levin
    Neoplasms of the testis / Charles C. Guo.
    Digital Access ClinicalKey 2015
  • Digital
    Cristina Magi-Galluzzi, Christopher G. Przybycin, editors.
    Summary: This book provides a comprehensive, state-of-the art review of the genitourinary tumor pathology field and the most contemporary insights regarding specimen submission, histologic morphology, immunohistochemistry, and molecular studies useful in the diagnosis of genitourinary neoplasms. Discussion of the clinical implications of pathological findings is contributed by renowned clinicians in the field. This handsome volume guides the reader through the intricacies of genitourinary tumor pathology, diagnosis, reporting, and prognosis. Written by experts in the field, Genitourinary Pathology: Practical Advances is of great value to anatomic pathologists, urologists, fellows in genitourinary pathology, as well as upper level residents training in pathology .

    Contents:
    Anatomy of the Prostate Revisited: Implications for Prostate Biopsy and Zonal Origins of Prostate Cancer
    Contemporary Gleason Grading System
    Contemporary Prostate Cancer Staging
    Prostate Cancer Reporting on Biopsy and Radical Prostatectomy Specimens
    Unusual Epithelial and Non-Epithelial Neoplasms of the Prostate
    Management Implications Associated with Unusal Morphologic Entities of the Prostate
    Nomograms for Prostate Cancer Decision-Making
    Genetic Determinants of Familial and Hereditary Prostate Cancer
    New Molecular Markers of Diagnosis and Prognosis in Prostate Cancer
    Intraoperative Consultation for Prostate Tumors: Challenges and Implications for Treatment
    Genomics and Epigenomics of Prostate Cancer
    Anatomy of the Urinary Bladder Revisited: Implications for Diagnosis and Staging of Bladder Cancer
    Classification and Histologic Grading of Urothelial Neoplasms by the WHO 2004 (ISUP 1998) Criteria
    Reporting of Bladder Cancer in TURBT and Cystectomy Specimens
    Urothelial Carcinoma Variants: Morphology and Association with Outcomes
    Independent Predictos of Clinical Outcomes and Prediction Models on Bladder and Upper Urinary Tract Cancer
    Familial Urothelial Carcinomas
    New Molecular Markers with Diagnostic and Prognostic Values in Bladder Cancer
    Intraoperative Consultation for Bladder Tumors: Challenges and Implications for Treatment
    Genetic and Epigenetic Alterations in Urothelial Carcinoma
    Urine Cytology
    Anatomy of the Kidney Revisited: Implications for Diagnosis and Staging of Renal Cell Carcinoma
    Classification of Adult Renal Tumors and Grading of Renal Cell Carcinoma
    Tumor Staging for Renal Pathology
    Surgical Pathology Reporting of Renal Cell Carcinomas
    Newly Described Entities in Renal Tumor Pathology
    Clinical and Management Implications Associated with Histologic Subtypes of Renal Cell Carcinomas
    Independent Predictors of Clinical Outcomes and Prediction Models for Renal Tumor Pathology
    Pathology of Inherited Forms of Renal Carcinoma
    The Utility of Immunohistochemistry in the Differential Diagnosis of Renal Cell Carcinomas
    Intraoperative Consultations for Renal Masses: Challenges and Implications for Treatment
    Genetic and Epigenetic Alterations in Renal Cell Carcinoma
    Role of Needle Biopsy in Renal Masses: Past, Present, Future
    Anatomy of the Testis and Staging of its Cancers: Implications for Diagnosis
    Classification of Testicular Tumors
    Testicular Cancer Reporting on Radical Orchiectomy and Retroperitoneal Lymph Node Dissection After Treatment
    Difficult or Newly Described Morphologic Entities in Testicular Neoplasia
    Clinical Implications of the Differnt Histologic Subtypes of Testicular Tumors
    Familial Syndromes Associated with Testicular Tumors
    Molecular and Immunohistochemical Markers of Diagnostic and Prognostic Value in Testicular Tumors
    Intraoperative Consultations for Testicular Tumors: Challenges and Implications for Treatment
    Genetic and Epigenetic Alterations in Testicular Tumors.
    Digital Access Springer 2015
  • Digital
    N. Reed Dunnick, Jeffrey H. Newhouse, Richard H. Cohan, Katherine E. Maturen.
    Contents:
    Congenital anomalies
    Functional renal anatomy, renal physiology, and contrast media
    The adrenal gland
    The retroperitoneum
    Renal cystic disease
    Renal tumors
    Renal inflammatory disease
    Renal failure
    Renal transplantation
    Vascular diseases
    Urolithiasis and nephrocalcinosis
    Pelvicalyceal system and ureter
    The urinary bladder
    Prostate and seminal vesicles
    Urethra and penis
    Scrotum and contents
    Ovaries and adnexae
    Uterus and cervix
    Female perineum and vagina
    Urinary tract trauma.
    Digital Access Ovid 2018
  • Digital
    Christopher J. VanderBussche, Carla L. Ellis, editors.
    Summary: This book covers the full spectrum of benign and malignant conditions of the genitourinary tract with emphasis on common entities encountered in daily practice. The volume is heavily illustrated and contains useful algorithms that guide the reader through the differential diagnosis and cyto-histologic correlation of common and uncommon entities with appropriate clinical correlations. This book will serve as a valuable quick reference for pathologists, cytopathologists, cytotechnologists, fellows and residents in the field. Genitourinary system cytopathology specimens and small biopsies are common specimens, with a growing number of renal fine needle aspirations and core biopsy procedures being performed each year. Genitourinary System Cytology and Small Biopsy Specimens focuses on the correlation between urinary tract cytology and surgical pathology, including the evaluation of germ cell tumor metastasis to distant sites. Aspiration and exfoliative cytology samples obtained from all areas of and related to the genitourinary tract are highlighted in individualized chapters for these entities. The growing body of information in personalized medicine and molecular discoveries in the field of genitourinary pathology demands focus as well; hence an integrated approach to molecular diagnostics is presented in each chapter. In summary, this book will provide an illustrative and algorithmic approach to every day practice of genitourinary cytopathology and small biopsy material, using appropriate cytologic-histologic correlation format and incorporating recent updates in terminology, guidelines, and ancillary studies.

    Contents:
    Urinary Tract Exfoliative Cytology & Biopsy Specimens: Non-Neoplastic Findings
    Urinary Tract Exfoliative Cytology & Biopsy Specimens: Low Grade Urothelial Neoplasms
    Urinary Tract Exfoliative Cytology & Biopsy Specimens: High Grade Urothelial Carcinoma
    Urinary Tract Exfoliative Cytology & Biopsy Specimens: Other Urothelial Tract Neoplasms
    Renal Fine Needle Aspiration & Core Biopsy Specimens: Renal Cell Carcinomas
    Renal Fine Needle Aspiration & Core Biopsy Specimens: Urothelial Carcinoma and other Non-Renal Malignancies
    Renal Fine Needle Aspiration & Core Biopsy Specimens: Benign Entities and Non-Neoplastic Findings
    Adrenal Gland
    Fine Needle Aspiration & Core Biopsy Specimens: Germ Cell Neoplasms
    Miscellaneous Lesions of the Genitourinary System.
    Digital Access Springer 2022
  • Print
    volume editors, Bruce Birren ... [et al.].
    Contents:
    v. 1. Analyzing DNA
    v. 2. Detecting genes
    v. 3. Cloning systems
    v. 4. Mapping genomes.
    Print Access Request
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    Stored offsite. Please request print.
    QH445.2 .G4645
    4
  • Digital
    K.V. Chaitanya.
    Summary: This book provides a detailed and up-to-dated information on the genomes belonging to three major life forms on Earth - archaea, prokaryotes and eukaryotes. Each section describes about the genome of a specific group of organisms, such as viruses, archaea, bacteria, eukaryotes and organellar genomes. Individual chapters provide details of their organization, structure, evolution, sequencing strategies and functions. Further, this book discusses the technologies that are applied for genome sequencing; assembly, annotation and gene prediction. Other topics include the genomes of important model organisms, mitochondria genome of Neanderthal fossil, etc. This book also examines the evolution of chloroplast and mitochondria genomes by comparing with bacteria, addresses the diseases that occur in humans due to the mutations in mitochondrial genome, gene therapy and engineering of chloroplast and mitochondrial genomes. Lastly, it features an overview of the role of proteomics, exposomics, connectomics, metabolomics, and microbiomics. This book is a fascinating read for students, lecturers and researchers in the field of genetics, genomics, microbiology and life sciences.

    Contents:
    Chapter 1. Structure and Organization of Virus Genomes
    Chapter 2. Archaeal Genomics
    Chapter 3. Structure, Function, and Evolution of Bacterial Genomes
    Chapter 4. Organellar Genome Analysis
    Chapter 5. Eukaryotic Genome Organization, Regulation, Evolution, and Control
    Chapter 6. Genome sequencing, Assembly and Annotation
    Chapter 7. Other Omics Integrated into Biosciences
    Chapter 8.Application of genomics
    Chapter 9. Important Databases Related to the Genomes.
    Digital Access Springer 2019
  • Digital
    Ju Han Kim.
    Summary: This textbook describes recent advances in genomics and bioinformatics and provides numerous examples of genome data analysis that illustrate its relevance to real world problems and will improve the reader's bioinformatics skills. Basic data preprocessing with normalization and filtering, primary pattern analysis, and machine learning algorithms using R and Python are demonstrated for gene-expression microarrays, genotyping microarrays, next-generation sequencing data, epigenomic data, and biological network and semantic analyses. In addition, detailed attention is devoted to integrative genomic data analysis, including multivariate data projection, gene-metabolic pathway mapping, automated biomolecular annotation, text mining of factual and literature databases, and integrated management of biomolecular databases. This textbook is primarily intended for life scientists, medical scientists, statisticians, data processing researchers, engineers, and other beginners in bioinformatics who are experiencing difficulty in approaching the field. However, it will also serve as a simple guideline for experts unfamiliar with the new, developing subfield of genomic analysis within bioinformatics.

    Contents:
    Part 1. BIOINFORMATICS FOR LIFE AND PERSONAL GENOME INTERPRETATION
    Chapter 1. Bioinformatics For Life
    Chapter 2. Next Generation Sequencing and Personal Genome Data Analysis
    Chapter 3. Personal Genome Data Analysis
    Chapter 4. Personal Genome Interpretation and Disease Risk Prediction
    Part 2. ADVANCED MICROARRAY DATA ANALYSIS
    Chapter 5. Advanced Microarray Data Analysis
    Chapter 6. Gene Expression Data Analysis
    Chapter 7. Gene Ontology and Biological Pathway-based Analysis
    Chapter 8. Gene-set Approaches and Prognostic Subgroup Prediction
    Chapter 9. MicroRNA Data Analysis
    Part 3. NETWORK BIOLOGY, SEQUENCE, PATHWAY AND ONTOLOGY INFORMATICS
    Chapter 10. Network Biology, Sequence, Pathway and Ontology Informatics
    Chapter 11. Motif and Regulatory Sequence Analysis
    Chapter 12. Molecular Pathways and Gene Ontology
    Chapter 13. Biological Network Analysis
    Part 4. SNPS, GWAS AND CNVS, INFORMATICS FOR GENOME VARIANTS
    Chapter 14. SNPs, GWAS, CNVs: Informatics for Human Genome Variations
    Chapter 15. SNP Data Analysis
    Chapter 16. GWAS Data Analysis
    Chapter 17. CNV Data Analysis
    Part 5. METAGENOME AND EPIGENOME, BASIC DATA ANALYSIS
    Chapter 18. Metagenome and Epigenome Data Analysis
    Chapter 19. Metagenome Data Analysis
    Chapter 20. Epigenome Databases and Tools
    Chapter 21. Epigenome Data Analysis
    Appendix A. BASIC PRACTICE USING R FOR DATA ANALYSIS
    Appendix B. APPLICATION PROGRAM FOR GENOME DATA ANALYSIS INSTALL GUIDE.
    Digital Access Springer 2019
  • Digital/Print
    Toni Cathomen, Matthew Hirsch, Matthew Porteus, editors.
    Contents:
    Gene editing 20 years later
    The development and use of zinc-finger nucleases
    The use and development of TAL effector nucleases
    Genome editing for neuromuscular diseases
    Phage integrases for genome editing
    Precise genome modification using triplex forming oligonucleotides and peptide nucleic acids
    Genome editing by Aptamer-Guided Gene Targeting (AGT)
    Stimulation of AAV gene editing via DSB repair
    Engineered nucleases and trinucleotide repeat diseases
    Using engineered nucleases to create HIV-resistant cells
    Strategies to determine off-target effects of engineered nucleases
    Cellular engineering and disease modeling with gene-editing nucleases
    Index.
    Digital Access Springer 2016
  • Digital
    edited by Krishnarao Appasani ; with a foreword by George M. Church.
    Summary: Recent advances in genome editing tools using endonucleases such as TALENs, ZFNs, and CRISPRs, combined with genomic engineering technologies, have opened up a wide range of opportunities from applications in the basic sciences and disease biology research, to the potential for clinical applications and the development of new diagnostic tools. This complete guide to endonuclease-based genomic engineering gives readers a thorough understanding of this rapidly expanding field. Chapters cover the discovery, basic science, and application of these techniques, focusing particularly on their potential relevance to the treatment of cancer, and cardiovascular and immunological disease. The final section discusses the legal and ethical issues which accompany the technology. Providing authoritative coverage of the potential that genome editing and engineering have, this is an ideal reference for researchers and graduate students and those working in the biotechnology and pharmaceutical industries, as well as in a clinical setting.
    Digital Access Cambridge 2018
  • Digital
    Bidyut Kumar Sarmah, Basanta Kumar Borah, editors.
    Summary: This book serves the teachers, researchers and the students as a handy and concise reference as well as guidebook while designing and planning for use of the advanced technologies for crop improvement. The content of the book is designed to cover the latest genome engineering techniques for crop improvement. The conventional breeding has got its limitations such as non-availability of desired genes within the genepool. In many cases, breeding has been highly used and it has nearly reached its highest limit so far as the productivity and production of crops are concerned. However, with increasing need of food and decreasing resources, including water, land, labour, etc., to feed the growing population, the alternative available ways of increasing crop productivity need to be explored and exploited. Genome engineering has a wide scope that includes technologies such as genetic engineering and transgenesis, RNA technologies, CRISPR, cisgenics and subgenics for better productivity and more efficient biotic and abiotic stress management. Therefore, the book is planned to enlighten the readers with the advanced technologies with examples and case studies, whenever possible. Efforts will be made to emphasize on general efforts on various major food crops; however, it would also be made clear that such efforts could be taken as proofs of concepts and that this could be extrapolated keeping the demand in mind.

    Contents:
    Source-Sink relationships and its effect on plant productivity: manipulation of primary carbon and starch metabolism
    Transgenic Approaches to Develop Virus Resistance in Rice
    Virus free improved food in the era of bacterial immunity
    Host-induced gene silencing (HIGS): An emerging strategy for the control of fungal plant diseases
    Genetic Engineering for Biotic Stress Management in Rice
    Genome improvement for rust disease resistance in wheat
    Novel technologies for transgenic management for plant virus resistance
    Cisgenesis: Engineering plant genomes by harnessing compatible gene pools
    Improving biotic and abiotic stress tolerance in plants: A CRISPR-Cas approach
    RNA interference (RNAi) in Functional Genomics of Wheat.
    Digital Access Springer 2021
  • Print
    Euan Angus Ashley, M.D., Ph.D.
    Summary: "In The Genome Odyssey, Dr. Euan Ashley, Stanford professor of medicine and genetics, brings the breakthroughs of precision medicine to vivid life through the real diagnostic journeys of his patients and the tireless efforts of his fellow doctors and scientists as they hunt to prevent, predict, and beat disease. Since the Human Genome Project was completed in 2003, the price of genome sequencing has dropped at a staggering rate. It's as if the price of a Ferrari went from $350,000 to a mere forty cents. Through breakthroughs made by Dr. Ashley's team at Stanford and other dedicated groups around the world, analyzing the human genome has decreased from a heroic multibillion dollar effort to a single clinical test costing less than $1,000. For the first time we have within our grasp the ability to predict our genetic future, to diagnose and prevent disease before it begins, and to decode what it really means to be human. In The Genome Odyssey, Dr. Ashley details the medicine behind genome sequencing with clarity and accessibility. More than that, with passion for his subject and compassion for his patients, he introduces readers to the dynamic group of researchers and doctor detectives who hunt for answers, and to the pioneering patients who open up their lives to the medical community during their search for diagnoses and cures. He describes how he led the team that was the first to analyze and interpret a complete human genome, how they broke genome speed records to diagnose and treat a newborn baby girl whose heart stopped five times on the first day of her life, and how they found a boy with tumors growing inside his heart and traced the cause to a missing piece of his genome. These patients inspire Dr. Ashley and his team as they work to expand the boundaries of our medical capabilities and to envision a future where genome sequencing is available for all, where medicine can be tailored to treat specific diseases and to decode pathogens like viruses at the genomic level, and where our medical system as we know it has been completely revolutionized"-- Provided by publisher.

    Contents:
    Preface
    Part I: The early genomes. Patient Zero
    Team of teams
    Once removed
    Genome illumination
    First family
    Buffalo buffalo buffalo
    Starting up, reaching out
    Part II: Disease detectives. Undiagnosed
    The luck of the Irish
    Next-day delivery
    Hoofbeats in Central Park
    Part III: Affairs of the heart. Whisky à go-go
    How many genomes are you?
    Shake, rattle, and roll
    River of the land of pine trees
    Songs in the key of life
    Part IV: Precisely accurate medicine. Superhumans
    Precision medicine
    Genome surgery
    The road ahead.
    Print Unavailable: Checked out Recall Item
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    Books: General Collection (Downstairs)
    QH447 .A84 2021
    1
  • Digital
    Tatsuhiko Tsunoda, Toshihiro Tanaka, Yusuke Nakamura, editors.
    Summary: This book examines the utility of genome-wide association studies (GWAS) in the era of next-generation sequencing and big data, identifies limitations and potential means of overcoming them, and looks to the future of GWAS and what may lay beyond. GWAS are among the most powerful tools for elucidating the genetic aspects of human and disease diversity. In Genome-Wide Association Studies, experts in the field explore in depth the impacts of GWAS on genomic research into a variety of common diseases, including cardiovascular, autoimmune, diabetic, cancer, and infectious diseases. The book will equip readers with a sound understanding both of the types of disease and phenotypes that are suited for GWAS and of the ways in which a road map resulting from GWAS can lead to the realization of personalized/precision medicine: functional analysis, drug seeds, pathway analysis, disease mechanism, risk prediction, and diagnosis.

    Contents:
    Genotyping and Statistical Analysis
    Genetics of coronary artery disease
    Genetic and Functional Genetics of Autoimmune Diseases
    Genome-Wide Association Study for Type 2 diabetes
    The association of single nucleotide polymorphisms with cancer risk
    Genetics of Infectious Diseases
    Pharmacogenomics
    The Future of and Beyond GWAS.
    Digital Access Springer 2019
  • Digital
    edited by Geoffrey S. Ginsburg, Huntington F. Willard.
    Contents:
    Family health history and health risk assessment for cardiovascular disease in health care
    Personalized lifestyle medicine
    Lipoprotein disorders
    Metabolic syndrome
    Hypertension
    Novel approaches to cardiovascular diagnostics : focus on coronary artery disease and myocardial infarction
    Hypertrophic cardiomyopathy in the era of genomic medicine
    Genomics to predict risk of coronary artery disease
    Genomics-guided antithrombotic therapy for acute coronary syndromes
    Heart failure : impact of genetics and genomics
    Arrhythmia genomics
    Genetics and genomics of peripheral arterial disease
    Genetic basis of congenital heart disease
    Perioperative genomics
    Genomics of ischemic stroke and prospects for clinical applications
    Cardiovascular pharmacogenetics.
    Digital Access ClinicalKey 2018
  • Digital
    edited by Geoffrey S. Ginsburg, Huntington F. Willard.
    Summary: "Genomic and Precision Medicine: Translation and Implementation highlights the various points along the continuum from health to disease where genomic information is impacting clinical decision-making and leading to more personalization of health care. The book pinpoints the challenges, barriers, and solutions that have been, or are being, brought forward to enable translation of genome based technologies into health care. A variety of infrastructure (data systems and EMRs), policy (regulatory, reimbursement, privacy), and research (comparative effectiveness research, learning health system approaches) strategies are also discussed. Readers will find this volume to be an invaluable resource for the translational genomics and implementation science that is required to fully realize personalized health care"--Publisher's description.

    Contents:
    Application of human genome information to clinical practice
    Genome sequencing: new technologies, approaches, applications
    Clinical applications of whole-genome chromosomal microarray analysis
    Transcriptomics in the age of ultra high-throughput sequencing
    Quantitative proteomics in genomic medicine
    Translating genome information into clinical practice and human health
    Big data and translational bioinformatics genomic and personalized medicine
    Biospecimen banking linked to phenotype data
    Electronic health records
    Data sharing and privacy
    Designing genome-based clinical studies
    Developing the evidence to support clinical use genomic biomarkers as diagnostics
    Strategies in the adoption of genome-based diagnostics
    Companion diagnostics
    Health risk assessment and family history
    Clinical decision support
    Implementation science and integration into healthcare systems
    Pharmacogenetics and pharmacogenomics
    Drug repurposing and repositioning
    Point of care devices
    Overview of policy, ethical and social considerations
    Educational issues and strategies for genomic medicine:
    For professionals
    For the public
    Regulation of genomic technologies
    Economic value of genomic medicine
    Reimbursement
    Impact of patents on genomic medicine.
    Digital Access ClinicalKey 2017
  • Digital
    series editors: Geoffrey S. Ginsburg, Huntington F. Willard; volume editors: Ephraim L. Tsalik, Christopher W. Woods.
    Digital Access ClinicalKey 2019
  • Digital/Print
    edited by Sean P. David ; series editors, Geoffrey S. Ginsburd, Huntington F. Willard.
    Contents:
    Genomic medicine in primary care / Samuel G. Johnson
    Overview of policy, ethical, and social considerations in genomic and personalized medicine / Susanne B. Haga
    Educational issues and strategies for genomic medicine / Jean Jenkins and Laura Lyman Rodriguez
    Genetic testing for rare and undiagnosed diseases / Thomas Morgan
    Health risk assessments, family health history, and predictive genetic/pharmacogenetic testing / Maria Esperanza Bergendahl, Lori A. Orlando and Latha Palaniappan
    Pharmacogenetics and pharmcogenomics / J. Kevin Hicks and Howard L. McLeod
    Hypertension / Patricia B. Munroe and Helen R. Warren
    Coronary artery disease / Themistocles L. Assimes
    Lung cancer / Yaron B. Gesthalter, Ehab Billatos and Haseena Kathuria
    Breast cancer / Paul K. Marcom
    Colorectal cancer / Roland P. Kuiper, Robbert D.A. Weren and Ad Geurts van Kessel --Prostate cancer / Wennuan Liu, Rong Na, Carly Conran and Jianfeng Xu
    Asthma / Michael J. McGeachie, Damien C. Croteau-Chonka and Scott T. Weiss
    Diabetes / Miriam S. Udler and Jose C. Florez
    Metabolic syndrome / Matthew B. Lanktree and Robert A. Hegele
    Autism spectrum disorder / Akanaksha Saxena and Maria Chahrour
    Viral hepatitis / Thomas Tu, Keyur Patel and Nicholas A. Shackel.
    Digital Access
    Provider
    Version
    ScienceDirect
    ClinicalKey
    Print Access Request
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    Books: General Collection (Downstairs)
    RB155 .G46 2017
    1
  • Digital
    George Jabboure Netto, Iris Schrijver, editor.
    Summary: Genomic Applications in Pathology provides a state-of-the art review of the scientific principles underlying next generation genomic technologies and the required bioinformatics approaches to analyses of the daunting amount of data generated by current and emerging genomic technologies. Implementation roadmaps for various clinical assays such as single gene, gene panels, whole exome and whole genome assays are discussed together with issues related to reporting, including the pathologist?s role in interpretation and clinical integration of genomic tests results. Genomic applications for site-specific solid tumors and hematologic neoplasms are detailed, as well as genomic applications in pharmacogenomics, inherited genetic diseases, and infectious diseases. The latest iteration of practice recommendations and guidelines in genomic testing, put forth by stakeholder professional organizations such as the Association for Molecular Pathology and the College of American Pathologists, are also discussed in the volume, as well as regulatory issues and laboratory accreditation related to genomic testing. Written by experts in the field, Genomic Applications in Pathology provides a comprehensive resource that is of great value to practicing molecular pathologists, hematopathologists, other subspecialized pathologists, general pathologists, pathology trainees, oncologists, and geneticists.

    Contents:
    Current Massively Parallel Sequencing Technologies: Platforms and Reporting Considerations
    Emerging Next Generation Sequencing Technologies
    Transcriptome Sequencing (RNA-Seq)
    miRNA Expression Assays
    Circulating Tumor Cells: Enrichment and Genomic Applications
    Circulating Cell-free DNA for Molecular Diagnostics and Therapeutic Monitoring
    Genomic Pathology: Training for New Technology
    Implementation of Genomic Sequencing Assays
    Regulatory and Reimbursement Issues in Genomic Testing
    Patents and Proprietary Assays
    Ethical Issues in Clinical Genetics and Genomics
    Transitioning Discoveries from Cancer Genomics Research Laboratories into Pathology Practice
    Bioinformatics Tools in Clinical Genomics
    Next Generation Sequencing for Single Gene Analysis
    Next Generation Sequencing for Gene Panels
    Implementation of Exome Sequencing Assays
    Implementation of Genome Sequencing Assays
    Clinical Information Systems in the Era of Personalized Medicine
    Reporting Clinical Genomic Assay Results and the Role of the Pathologist
    Genomic Applications in Hematologic Oncology
    Genomic Applications in Brain Tumors
    Genomic Applications in Head and Neck Cancers
    Genomic Applications in Breast Carcinoma
    Genomic Applications in Pulmonary Malignancies
    Genomic Applications in Colorectal and Pancreatic Tumors
    Molecular Pathology of Genitourinary Cancers: Translating the Cancer Genome to the Clinic
    Genomic Applications in Gynecologic Malignancies
    Genomic Applications in Epithelial Ovarian Malignancies
    Genomic Applications in Soft Tissue Sarcomas
    Genomic Applications in Inherited Genetic Disorders
    Genomic Applications in Pharmacogenomics
    Sequencing Cell Free DNA in the Maternal Circulation to Screen for Down Syndrome and Other Common Aneuploidies
    Genomic Applications in the Clinical Management of Infectious Diseases. .
    Digital Access Springer 2015
  • Digital
    George Jabboure Netto, Karen L. Kaul, editors.
    Digital Access Springer 2019
  • Digital
    edited by Yihong Yao, Bahija Jallal, Koustubh Ranade.
    Summary: Genomic Biomarkers for Pharmaceutical Development: Advancing Personalized Health Care provides an in-depth review of the state of translational science across all stages of pharmaceutical development with a special focus on personalized health care. This book provides a complete picture of biomarker development and validation in a pharmaceutical setting while addressing the inherent challenges of targeting the appropriate indications, biomarker robustness, regulatory hurdles, commercialization and much more. It features case studies devoted to the applications of pharmacogenomics, toxicogenomics, and other genetic technologies as they support drug discovery and development. With chapters written by international authorities in industry and academia, this work is a truly unique presentation of the thoughts and approaches that lead to the development of personalized medicine. Intended for all those involved in clinical translational research, this book is the ideal resource for scientists searching for the applications, strategies and successful approaches of translational science in pharmaceutical development. Provides case studies in applications of pharmacodynamic and predictive markers in drug development in oncology, autoimmunity, respiratory diseases and infectious diseases. Shows how to identify potential new therapeutic targets in different diseases and provides examples of potential new disease indications for life cycle management of drugs. Authored by leading international experts from industry and academia.

    Contents:
    1. Application of translational science to clinical development / Koustubh Ranade [and five others]
    2. Personalized health care (PHC) in cancer / Nicholas C. Dracopoli, Katie Streicher
    3. Personalized healthcare in autoimmune diseases / Cornelis L. Verweij, Brandon W. Higgs, Yihong Yao
    4. Molecular heterogeneity, biomarker discovery, and targeted therapy in asthma / Joseph R. Arron, Jeffrey M. Harris
    5. microRNA biomarkers as potential diagnostic markers for cancer / Elizabeth Mambo [and five others]
    6. Toxicogenomics
    a drug development perspective / Yuping Wang, Jurgen Borlak, Weida Tong
    7. Translating biomarker discovery into companion diagnostics through validation and regulatory consideration / Philip Brohawn [and four others].
    Digital Access ScienceDirect 2014
  • Digital
    Chittaranjan Kole, editor.
    Summary: This book highlights modern methods and strategies to improve cereal crops in the era of climate change, presenting the latest advances in plant molecular mapping and genome sequencing. Spectacular achievements in the fields of molecular breeding, transgenics and genomics in the last three decades have facilitated revolutionary changes in cereal- crop-improvement strategies and techniques. Since the genome sequencing of rice in 2002, the genomes of over eight cereal crops have been sequenced and more are to follow. This has made it possible to decipher the exact nucleotide sequence and chromosomal positions of agroeconomic genes. Most importantly, comparative genomics and genotyping-by-sequencing have opened up new vistas for exploring available biodiversity, particularly of wild crop relatives, for identifying useful donor genes. -- Provided by publisher.

    Contents:
    Genomics-assisted breeding of climate-smart inbred and hybrid rice varieties / Jauhar Ali, Anumalla Mahender, G. D. Prahalada, Ma. Anna Lynn Sevilla, Angelito Galang, Erik Jon De Asis et al.
    Advanced genomics and breeding tools to accelerate the development of climate resilient wheat / Yuanfeng Hao, Awais Rasheed, Robert Jackson, Yonggui Xiao, Yong Zhang, Xianchun Xia et al.
    Increasing genetic gains in maize in stress-prone environments of the tropics / B. M. Prasanna, Sudha K. Nair, Raman Babu, Manje Gowda, Xuecai Zhang, Yunbi Xu et al.
    Genomic approaches for climate resilience breeding in oats / Julio Isidro-Sánchez, Elena Prats, Catherine Howarth, Tim Langdon, Gracia Montilla-Bascón
    Genomic designing for climate smart sorghum / Ganapathy Kuyyamudi Nanaiah, Sujay Rakshit
    Genomic designing of pearl millet : a resilient crop for arid and semi-arid environments / Desalegn D. Serba, Rattan S. Yadav, Rajeev K. Varshney, S. K. Gupta, Govindaraj Mahalingam, Rakesh K. Srivastava et al.
    Genomic designing for climate smart finger millet / Damaris Achieng Odeny, Adnan Niazi, Kassahun Tesfaye, Dagnachew Lule, Solomon Wanyonyi, Josephine Sarah Kunguni.
    Digital Access Springer 2020
  • Digital
    Chittaranjan Kole, editor.
    Summary: This edited book provides a comprehensive overview of modern strategies in fruit crop breeding in the era of climate change and global warming. It demonstrates how advances in plant molecular and genomics-assisted breeding can be utilized to produce improved fruit crops with climate-smart traits. Agriculture is facing a number of challenges in the 21st century, as it has to address food, nutritional, energy and environmental security. Future fruit varieties must be adaptive to the varying scenarios of climate change, produce higher yields of high-quality food, feed, and fuel and have multiple uses. To achieve these goals, it is imperative to employ modern tools of molecular breeding, genetic engineering and genomics for precise plant breeding to produce designed fruit crop varieties. This book is of interest to scientists working in the fields of plant genetics, genomics, breeding, biotechnology, and in the disciplines of agronomy and horticulture.

    Contents:
    Intro
    Preface
    Contents
    Abbreviations
    1 Genomic Designing for New Climate-Resilient Almond Varieties
    1.1 Introduction
    1.2 Designing Climate-Resilient Almond Varieties
    1.3 Prioritizing Climate-Smart (CS) Agronomic Traits
    1.3.1 Flowering Time
    1.3.2 Cold Tolerance
    1.3.3 Drought Resistance
    1.3.4 Chemical and Nutritional Values
    1.4 Marker-Assisted Breeding for CS Traits
    1.4.1 Development and Application of DNA Markers
    1.4.2 Development and Application of RNA Markers
    1.4.3 Development and Application of Epigenetic Marks 1.5 Concluding Remark and Future Prospects
    References
    2 Challenges and Strategies for Developing Climate-Smart Apple Varieties Through Genomic Approaches
    2.1 Introduction
    2.2 Impact of Climate Change on Apple
    2.3 Need for Adaptation to Climate Change
    2.4 Efforts to Develop Climate-Smart Apple Varieties
    2.4.1 Dormancy and Dormancy Release
    2.4.2 Abiotic Stress
    2.4.3 Biotic Stress
    2.4.4 Fruit Quality
    2.4.5 Root Stock Characterization
    2.5 Molecular Mapping of Genes/QTLs
    2.6 Digital Breeding for Development of Climate-Smart Apple Varieties 2.6.1 Apple Databases
    2.6.2 Other Digital Resources Available for the Apple Breeders
    2.6.3 Data Repositories for the Gene Banks
    2.6.4 Digital Image-Based Phenotyping
    2.7 Concluding Remark and Future Prospects
    References
    3 Genomic Designing for New Climate-Resilient Apricot Varieties in a Warming Context
    3.1 Introduction
    3.2 Design of New Climate-Resilient Apricot Varieties
    3.3 Prioritizing Climate-Smart (CS) Agronomic Traits
    3.3.1 Flowering Time
    3.3.2 Drought Resistance
    3.3.3 Fruit Quality and Nutritional Values
    3.4 Marker-Assisted Selection 3.4.1 Development and Application of DNA Markers
    3.4.2 Development and Application of RNA Markers
    3.4.3 Development and Application of Epigenetic Markers
    3.5 Concluding Remark and Future Prospects
    References
    4 Breeding Climate-Resilient Bananas
    4.1 Introduction
    4.2 The Structure and Physiology of Banana
    4.3 Plant Physiological Responses to Water Deficit
    4.4 Molecular Approaches to Drought Stress in Banana
    4.5 Breeding
    4.5.1 Defining the Scope of the Breeding Program
    4.5.2 Challenges Specific to Banana Breeding
    4.5.3 Phenotyping 4.5.4 Defining the Appropriate Environment for Phenotyping
    4.6 Recommendations
    References
    5 Toward Development of Climate-Resilient Citrus
    5.1 Introduction
    5.2 Prioritizing Climate-Smart (CS) Traits
    5.2.1 Role of Exogenous and Endogenous Factors in Flowering
    5.2.2 An Insight into the Responses of Citrus to Different Abiotic Stresses
    5.2.3 Molecular Mechanism of Citrus-Xylella Fastidiosa Interactions Revealed by Transcriptome Characterization
    5.3 Linkage Mapping and Quantitative Trait Loci (QTL) Analysis
    5.3.1 Genomics-Aided Breeding for CS Traits
    Digital Access Springer 2020
  • Digital
    Chittaranjan Kole, editor.
    Summary: This book highlights modern strategies and methods to improve oilseed crops in the era of climate change, presenting the latest advances in plant molecular breeding and genomics-driven breeding. Spectacular achievements in the fields of molecular breeding, transgenics and genomics in the last three decades have facilitated revolutionary changes in oilseed- crop-improvement strategies and techniques. Since the genome sequencing of rice, as the first crop plant, in 2002, the genomes of about one dozen oilseed crops have been sequenced and more are to follow. This has made it possible to decipher the exact nucleotide sequence and chromosomal positions of agroeconomic genes. Most importantly, comparative genomics and genotyping-by-sequencing have opened up new vistas for exploring available biodiversity, particularly of wild crop relatives, for identifying useful donor genes.

    Contents:
    Intro; Preface; Contents; Contributors; Abbreviations; 1 Approaches, Applicability, and Challenges for Development of Climate-Smart Soybean; Abstract; 1.1 Introduction; 1.2 Prioritizing Climate-Smart Traits; 1.2.1 Flowering Time and Maturity; 1.2.1.1 Overview of Flowering and Maturity Regulating Genes in Soybean; 1.2.1.2 Cloning Genes Underlying the Flowering and Maturity Traits; 1.2.1.3 Application of Classification of Maturity Group (MG) in Soybean; 1.2.2 Seed Composition; 1.2.2.1 Oil; Genetic Regulation of Seed Oil Production; Metabolic Engineering of Fatty Acid Composition 1.12.1 Achievements of Transgenic Approaches1.12.1.1 Insect Resistance; 1.12.1.2 Disease Resistance; 1.12.1.3 Abiotic Stress Resistance; 1.12.1.4 Herbicide Resistance; 1.12.1.5 Increased Oil Content; 1.13 Recent Concepts and Strategies Development; 1.13.1 Gene Editing; 1.13.1.1 Concerns and Compliances About Gene Editing and Genetically Modified Crops; 1.13.2 Nanotechnology; 1.14 Brief Account on the Role of Bioinformatics as a Tool; 1.14.1 Gene and Genome Databases; 1.14.1.1 Phytozome (http://www.phytozome.net/soybean); 1.14.1.2 SoyBase (http://soybase.org/index.php) 1.14.1.3 SoyGD (http://soybeangenome.siu.edu/)1.14.2 Soybean Omics Databases; 1.14.2.1 Gene Networks in Seed Development (http://estdb.biology.ucla.edu/seed/); 1.14.2.2 The Soybean Genomics and Microarray Database (SGMD) (http://psi081.ba.ars.usda.gov/SGMD/Default.htm); 1.14.2.3 SoyXpress (http://soyxpress.agrenv.mcgill.ca/); 1.14.2.4 The Soybean Proteome Database (SPD, http://proteome.dc.affrc.go.jp/soybean/); 1.14.2.5 Soybean Knowledge Base (SoyKB) (http://soykb.org/); References; 2 Genetic Solutions to Improve Resilience of Canola to Climate Change; Abstract; 2.1 Introduction 1.2.2.2 ProteinSeed Protein Composition; Genetic Regulation of Protein Content; 1.2.3 Abiotic Stress Tolerance; 1.2.3.1 Drought Tolerance; Root System Architectures and Anatomy; Water Use Efficiency and Canopy Wilting; Sustained N-Fixation Under Drought; 1.2.3.2 Waterlogging Tolerance; 1.2.3.3 Salt Tolerance; 1.2.3.4 Heat Tolerance; 1.2.3.5 Cold Tolerance; 1.2.4 Biotic Stress Tolerance; 1.2.4.1 Insect Resistance; 1.2.4.2 Disease Resistance; 1.2.5 Nutrient Use Efficiency; 1.3 Genetic Resources of Climate-Smart Genes; 1.4 Brief on Diversity Analysis 1.4.1 Phenotype-Based Diversity Analysis in Soybean Varieties1.4.2 Genotype-Based Diversity Analysis: Molecular Markers; 1.4.3 Relationship with Other Cultivated Species and Wild Relatives; 1.4.4 Relationship with Geographical Distribution; 1.5 Population Structures of Soybean in Nature; 1.6 Association Mapping Studies; 1.7 Brief Account of Molecular Mapping of CS Genes and QTLs; 1.8 Map-Based Cloning of CS Genes; 1.9 Marker-Assisted Breeding for CS Traits; 1.10 Genomic Resources; 1.11 Genomics-Assisted Breeding for CS Traits; 1.12 Brief on Genetic Engineering for CS Traits
    Digital Access Springer 2019
  • Digital
    Chittaranjan Kole, editor.
    Summary: This book describes the concepts, strategies and techniques for pulse-crop improvement in the era of climate change, highlighting the latest advances in plant molecular mapping and genome sequencing. Genetic mapping of genes and QTLs has broadened the scope of marker-assisted breeding and map-based cloning in almost all major pulse crops. Genetic transformation, particularly using alien genes conferring resistance to herbicide, insects and diseases has facilitated the development of a huge number of genetically modified varieties of the major pulse crops. Since the genome sequencing of rice in 2002, genomes of over 7 pulse crops have been sequenced. This has resulted in the possibility of deciphering the exact nucleotide sequence and chromosomal positions of agroeconomic genes. Most importantly, comparative genomics and genotyping-by-sequencing has opened up a new vista for exploring wild crop relatives for identification of useful donor genes.

    Contents:
    Common bean
    Pigeonpea Genomic interventions to improve resilience of pigeonpea in changing climate
    Chickpea Breeding and genomic approaches for sustaining chickpea yield under changing climate
    Lentil Towards climate resilient lentils-advances in abiotic and biotic stress resistance
    MungbeanGenomic perspectives towards development of climate-smart mungbean: Perspective and future
    Pea Title: Pea and Climate Change: Possibilities of Adaptation through Genomic Selection and Breeding
    Faba Bean Genomics-aided breeding for CS traits in Faba bean
    Bambara Groundnut: An old crop for the climate change era
    Lathyrus "Grass pea: Remodelling an ancient insurance crop for the 21st century."
    Digital Access Springer 2019
  • Digital
    Chittaranjan Kole, editor.
    Summary: This book reviews modern strategies in the breeding of vegetables in the era of global warming. Agriculture is facing numerous challenges in the 21st century, as it has to address food, nutritional, energy and environmental security. Future vegetable varieties must be adaptive to the varying scenarios of climate change, produce higher yields of high- quality food and feed and have multiple uses. To achieve these goals, it is imperative to employ modern tools of molecular breeding, genetic engineering and genomics for 'precise' plant breeding to produce 'designed' vegetable varieties adaptive to climate change. This book is of interest to scientists working in the fields of plant genetics, genomics, breeding, biotechnology, and in the disciplines of agronomy and horticulture.

    Contents:
    Climate-smart potato: An integrated breeding, genomics and phenomics approach
    Genomic designing for climate-smart tomato
    The importance of genetic and epigenetic research in the Brassica vegetables in the face of climate change
    Eggplant breeding and improvement for future climates.
    Digital Access Springer 2020
  • Digital
    Chris Maxwell, Cal Roskelley, editors.
    Summary: Metastasis is the primary cause of mortality associated with cancer, and tumor genomic heterogeneity is a likely source for the cells that support cancer progression, resistance to therapy, and disease relapse. This book connects cancer metastasis with genomic instability in a comprehensive manner. Section 1 outlines the fundamental mechanisms responsible for these cellular and tissue phenotypes. Section 2 discusses in silico, in vitro, and in vivo models used for the experimental study of these processes. Section 3 reviews emerging themes (ex., microenvironment, mechanotransduction, and immunomodulation), and Section 4 highlights new therapeutic approaches to overcome the unique challenges presented by the heterogeneous and metastatic tumor. This book is intended for undergraduates and postgraduates with an interest in the areas of medicine, oncology, and cancer biology as well as for the content expert searching for thorough reviews of current knowledge in these areas.

    Contents:
    Preface.- Cancer Metastasis: Tracking and Attacking a Moving Target.- The generation, detection, and prevention of genomic instability during cancer progression and metastasis.- DNA damage response pathways in cancer predisposition and progression.- Mathematical modeling for DNA repair, carcinogenesis and cancer detection.- Animal models of metastasis.- Microenvironmental Control Of Metastatic Progression.- 7 Mechanotransduction, metastasis and genomic instability
    8 Immunomodulation and Genomic Instability
    9 Synthetic Genetic Approaches in Colorectal Cancer: Exploiting and Targeting Genome Instability
    Nanomedicine ? Nanoparticles in Cancer Imaging and Therapy
    Index.
    Digital Access Springer 2015
  • Digital
    Laura J. Tafe, Maria E. Arcila, editors.
    Summary: The field of Molecular Diagnostics is rapidly evolving and molecular characterization of neoplasms is becoming an increasingly important part of the pathologic work up and diagnosis of many tumor types. This work provides a high-yield reference book that compiles critical information related to molecular biomarkers for various solid tumor and hematologic malignancy subtypes. It is succinct yet comprehensive enough to be suitable for fellows in training and medical professionals with an interest in molecular pathology and biomarkers. The book covers many aspects of molecular diagnostics, from techniques to applications and comprehensive summaries of the current molecular biomarkers of critical importance in solid and liquid tumors. Attention is also specifically devoted to bioinformatics and next generation sequencing, as well as pre-analytical issues that must be considered for accurate interpretation of molecular results in the context of overall patient care. This text focuses on clinical utility and validity and serves as an "owners manual" in Genomic Diagnostics for the practicing pathologist, pathology fellows and residents and other health care providers. Physicians will find this book invaluable as a quick reference for current molecular testing modalities and guidelines, tumor board preparation, deciding which test to order and interpreting genomic laboratory results. In addition, it is an accessible for trainees as a board review preparation reference.

    Contents:
    Pre-Analytics, Current Testing Technologies, and Limitations of Testing
    Next Generation Sequencing
    Cell Free DNA Testing
    Role of Bioinformatics in Molecular Medicine
    Interpreting Genomic Reports
    Lung Carcinoma
    GI including GIST
    Breast
    Genitourinary Tumors
    Gynecologic Malignancies
    Sarcomas
    Salivary Gland Carcinomas
    Sinonasal Carcinomas
    Acute Myeloid Neoplasms
    Chronic Myeloid Neoplasms
    Lymphomas.
    Digital Access Springer 2020
  • Digital
    edited by Catalina Lopez-Correa, George P. Patrinos.
    Summary: Genomic Medicine in Resource-limited Countries: Genomics for Every Nation provides in-depth analysis and key examples of the implementation of medical genomics in low-income nations across the globe, demonstrating how this advancing medical science has not only transformed health systems, but also led to improved patient care in Indonesian, Nepalese, Chilean, Malaysian, Tanzanian, Argentinian, Chinese, Sri Lankan and Columbian populations, among others. In addition to defining tools, diagnostics and treatment pathways at the population-wide level for medical geneticists, genomic researchers and public health workers, this book offers a case-study based approach that helps users understand how genomic medicine is used in disease-management.

    Contents:
    Front matter
    Copyright
    Contributors
    Genomic Medicine in Developing and Emerging Economies: State-of-the-Art and Future Trends
    Taking Genomics From the Bench to the Bedside in Developing Countries
    Genomics and Public Health: China’s Perspective
    Leveraging International Collaborations to Advance Genomic Medicine in Colombia
    Screening for Hereditary Cancer in Latin America
    Implementing Genomics in the Care of Neuropsychiatric Patients in Latin America
    Experience in the Development of Genomics Companies During the Last 20 Years in Argentina
    Economic Evaluation and Cost-Effectiveness Analysis of Genomic Medicine Interventions in Developing and Emerging Countries
    Raising Genomics Awareness Among the General Public and Educating Healthcare Professionals on Genomic Medicine
    The Genomic Medicine Alliance: A Global Effort to Facilitate the Introduction of Genomics into Healthcare in Developing Nations
    Index
    Digital Access ScienceDirect 2018
  • Digital
    Joel Ira Weller.
    Contents:
    Historical overview
    Types of current genetic markers and genotyping methodologies
    Advanced animal breeding programs prior to genomic selection
    Economic evaluation of genetic breeding programs
    Least squares, maximum likelihood and Bayesian parameter estimation
    Trait-based genetic evaluation, the mixed model
    Maximum likelihood and Bayesian estimation of QTL parameters with random effects included in the model
    Maximum likelihood, restricted maximum likelihood and Bayesian estimation for mixed models
    Distribution of genetic effects, theory and results
    The multiple comparison problem
    Linkage mapping of QTL
    Linkage disequilibrium mapping of QTL
    Marker assisted selection, basic strategies
    Genetic evaluation based on dense marker maps, basic strategies
    Genetic evaluation based on analysis of genetic evaluations or daughter-yield evaluations
    Genomic evaluation based on analysis of production records
    Validation of methods for genomic estimated breeding values
    Byproducts of Genomic evaluation analysis: pedigree validation and determination
    Imputation of missing genotypes : methodologies, accuracies, and effects on genomic evaluations
    Detection and validation of quantitative trait nucleotides (QTN)
    Future directions and conclusions.
    Digital Access Wiley 2016
  • Digital
    Babak Arjmand, editor.
    Contents:

    Chapter 1: Trying to reveal the mysteries of stem cells using "omics" strategies.-
    Chapter 2: Genomics, Proteomics, and Metabolomics for Stem Cells Monitoring in Regenerative Medicine.-
    Chapter 3: Metabolic profiling of the Mesenchymal Stem Cells' Secretome.-
    Chapter 4: Different Gene Expression Profile of Mesenchymal Stem Cells from Various Sources.-
    Chapter 5: Genomic and Proteomic Monitoring of Stem Cell-Derived Exosomes.-
    Chapter 6: Proteomics Approaches Applied to Regenerative Medicine; Perspectives in stem cell Proteomics.-
    Chapter 7: Lipidomics of Adipogenic Differentiation of Mesenchymal Stem Cells.-
    Chapter 8: OMICs Profiling of Cancer Cells.-
    Chapter 9: Genomics, Proteomics and Metabolomics of Cancer Stem Cells (CSCs).-
    Chapter 10: From OMICs to Ethics, points to start the debate.- Index.
    Digital Access Springer 2019
  • Digital
    György Marko-Varga, editor.
    Summary: This book offers a valuable resource that allows students, researchers, educators and the general public to learn about proteomics and genomics. Chromosomes form the basis for our genetic heritage and are the code for protein synthesis. The Human Genome Map was presented in 2002, and the Proteome Sequence Map is currently being created by a global consortia initiative. Proteome and genome building blocks already form the basis of scientific research areas and shape major areas of the pharmaceutical and biomedical industries. The book provides background information on and our current understanding of these gene and protein areas, and explains in detail how cutting-edge science is using these resources to develop new medicines and new diagnostics for patient treatment and care. The book will benefit all students and researchers who need a good understanding of genomics and proteomics within the clinical field. Its content is also suitable for a broad readership, including those not specialized in this field. Dr. Marko-Varga is head of Div. Clinical Protein Science & Imaging at the Biomedical Center, Dept. of Measurement Technology and Industrial Electrical Engineering, Lund University. He's also Professor at the 1st Department of Surgery, Tokyo Medical University, Tokyo, Japan.

    Contents:
    Introduction
    The Unknown Proteins Coded by the Human Chromosome
    Chromosome Transcript Profiling
    Standardization of Proteome Annotations
    Mass Spectrometry Protein Sequencing Technology Platforms
    Post Translational Modifications within the Human Proteome
    NAPPA Array
    Protein Microarray Technology
    Clinical Bioinformatics
    A New Emerging Science
    Computational Science within Genomics and Proteomics
    Rapid Advances in the Field of Epigenetics.
    Digital Access Springer 2014
  • Digital
    Vijay Rani Rajpal, Deepmala Sehgal, Avinash Kumar, S.N. Raina, editors.
    Summary: Abiotic Stress Tolerance Related Genomics-assisted Breeding for Crop Improvement Volume 2 is a compilation of the status of genomics-assisted breeding in various crops in the era of high throughput genotyping and phenotyping platforms. How scientists have utilized these new platforms on their germplasm for identification of novel genes and alleles for abiotic stress tolerance is described. The articles in the book include topics specifically in the areas of genetics and genomics of stomatal traits for improving drought tolerance, genomics-based approaches for improving abiotic stress tolerance, quantitative trait loci (QTL) mapping and association mapping for abiotic stress tolerance related traits and candidate genes for abiotic stress tolerance. In addition, chapters have been included on innovative role of double haploids in genomics-assisted crop improvement for abiotic stress tolerance. Overall, the collation will be very useful to scientists working in similar areas as well as to graduate and undergraduate students who want to get information of QTLs, genes etc. for a particular crop at one place.

    Contents:
    1. Progress towards identification of candidate genes for abiotic stress tolerance in wheat
    2. Genomics and molecular breeding for improving tolerance to abiotic stress in barley
    3. Genomics-Assisted Selection for Drought Tolerance in Maize
    4. Genomics-assisted breeding for enhanced drought tolerance in chickpea (Cicer arietinum L.)
    5. Genomics assisted approaches for improving abiotic stress tolerance in forage grasses
    6. Genomics-Assisted Breeding for Drought Tolerance in Cowpea
    7. Hybrid wheat and abiotic stress tolerance
    8. Innovative role of DH breeding in genomics assisted-crop improvement: focus on drought tolerance in Wheat
    9. Field Phenotyping Strategies for Peanut to Drought and Molecular Markers for Crop Improvement
    10. Developing Climate Resilient Versions of Popular Rice Varieties by Genomics-Assisted Backcross Breeding
    11. Genomics based approaches for enhancing abiotic stress tolerance in rice
    12. QTLs for abiotic stress resistance and their effectiveness for breeding in rice
    13. Molecular aspects of responses to cold stress in temperate fruit crops with emphasis on Rosaceae species
    14. Genomics-assisted breeding of foxtail millet (Setaria italica)
    15. Genomics of abiotic stress tolerance in soybeans
    16. Genetics and Genomics of Stomatal and Epidermal Cell Traits for Improving Drought Tolerance in cereals
    17. Genomics of abiotic stress response and management in sugarcane.
    Digital Access Springer 2019
  • Digital
    Yashwant Pathak, editor.
    Summary: This book evaluates trends arising in "--Omics" sciences in terms of their current and potential future application to therapeutic design and understanding of disease. Chapters consider the impact of pharmacogenomics and bioinformatics on drug development, as well as trends in genomics, as applied to understanding of neurodegenerative and lung disease, psychiatry and oncology. Following the genome studies released in early part of this century, the advent of the -Omics sciences (genomics and pharmacogenomics, proteomics, metabolomics, transcriptomics) has seen the expansion of a vast knowledgebase with utility in preventing and treating disease, and improving health for all. Bioinformatics and improved pharmacogenetic understanding forge a path for improved drug discovery and design methods accounting for differences in delivery and disposition across populations.

    Contents:
    Intro; Foreword; Preface; Omics-Driven Trends in Disease Prevention and Better Healthcare; Contents; Contributors;
    1: Rethinking Drug Discovery and Targeting After the Genomic Revolution; 1.1 Introduction; 1.2 Genomic Revolution; 1.3 Changing Scenario in Drug Discovery and Targeting; 1.3.1 A New Pattern for Drug Development in the Form of Pharmacogenomics; 1.3.2 Personalized Medicine for Individual Genomes; 1.4 Paradigm Shift in the Treatment of Disease in the Postgenomic Era; 1.4.1 Shift in Treatment and Drug Development for Cancer 1.4.2 Shift in Treatment and Drug Development for Cardiovascular Disease1.4.3 Shift in Treatment and Drug Development for Tuberculosis; References;
    2: Living Between Sickness and Health: Where Is the Human Genome Leading Us?; 2.1 Introduction; 2.2 Cancer; 2.2.1 Lung Cancer; 2.2.2 Breast Cancer; 2.2.3 Prostate Cancer; 2.2.4 Colorectal Cancer; 2.3 Cardiovascular System; 2.3.1 Coronary Heart Disease; 2.3.2 Pulmonary Arterial Hypertension; 2.3.3 Stroke; 2.3.4 Dyslipidemia; 2.4 Mental Illness; 2.4.1 Depression/Bipolar Disorder; 2.4.2 Parkinson's Disease; 2.4.3 Alzheimer's Disease 2.4.4 SchizophreniaReferences;
    3: Pharmacogenomics: Setting Newer Paradigms of Genetics in Therapy and Medicine; 3.1 Introduction; 3.2 Pharmacogenomics: Genetic Variability and Pharmacokinetics; 3.3 Pharmacogenetics and Drug Pharmacodynamics; 3.4 Different Types of Genetic Polymorphisms and Their Impact on Pharmacotherapy; 3.4.1 Single-Nucleotide Polymorphisms (SNPs); 3.4.2 Noncoding Region Polymorphisms; 3.4.2.1 Promoter Polymorphism; 3.4.2.2 5' and 3' UTR Polymorphism; 3.4.2.3 Splice Site Polymorphism; 3.4.2.4 Short Tandem Repeat Polymorphism 3.4.2.5 Insertion/Deletion Polymorphism (Indels)3.5 Technologies of Pharmacogenomics; 3.6 Clinical Relevance of Pharmacogenomics; 3.6.1 Side Effects and Toxicity; 3.6.2 Therapeutic Efficacy; 3.7 Applications of Pharmacogenomics; 3.7.1 Pharmacogenomics: Improving Productivity of Drug Development Process; 3.7.2 Pharmacogenomics: Establishing Drug Safety; 3.7.3 Pharmacogenomics: Development of Molecular Diagnostics; 3.7.4 Pharmacogenomics: Application for Personalized Medicine; 3.8 Pharmacogenomics and Its Impact on Pharmaceutical Market; 3.8.1 Market Segmentation 3.8.2 Market Expansion3.9 Challenges of Pharmacogenomics; 3.9.1 Financing Personalized Healthcare; 3.9.2 Ethical and Legal Issues; 3.9.3 Scientific Uncertainty; 3.10 Future Prospects of Pharmacogenomics; References;
    4: Bioinformatics and Pharmacogenomics: Tools to Understand and Accelerate Infectious Disease Control; 4.1 Introduction; 4.2 Infectious Diseases Scenario in Developing Countries; 4.3 Need for Developing Bioinformatics Tools; 4.4 Clinical Bioinformatics; 4.5 Bioinformatics Tools for Population Science Study; 4.5.1 Google Trends
    Digital Access Springer 2018
  • Digital
    Susan G. Dorsey, Angela R. Starkweather, editors.
    Summary: This book provides an overview of the field of pain genomics and the genomics of related, or co-occuring, symptoms, the current state-of-the-science, and challenges that remain. It brings differing views in the field together and provides examples of translational science from using cellular and rodent models to human clinical trials. This book's structure leads the reader through the physiology of pain and genomics into how pain is studied, mechanisms of acute and chronic pain, various protocols that are used throughout the field along with the pros/cons of the current methods used, and project into the future of pain genomics. This work is intended for classroom teaching, for nurses, for novice researchers in symptom science and pain research as well as students and postdoctoral fellows.

    Contents:
    Intro
    Contents
    1: History of Integrating Genomics in Nursing Research: The Importance of Omics in Symptom Science
    1.1 The Unique Perspective Nurse Scientists Bring to Symptom Science Research
    1.2 The History of Promoting Precision Health Research at NINR
    1.2.1 Harnessing the Future with Genetics and Genomics: Education and Funding Initiatives
    1.3 Efforts to Develop Nursing Research Expertise in Genomics and Symptom Science
    1.4 NIH Symptom Science Model
    1.5 NINR's Division of Intramural Research and Symptom Science 1.6 NINR's Support of Symptom Science and Omics Research
    1.6.1 Extramural Symptom Science and Omics Research Training
    1.7 Trans-NIH Initiatives
    1.7.1 The NIH Pain Consortium
    1.7.2 The All of Us Research Program
    1.7.3 Common Data Elements
    1.7.4 Repurposing Omics Data
    1.8 Conclusion
    References
    2: Introduction to Omics Approaches in Symptom Science
    2.1 Genomics
    2.2 Transcriptomics
    2.3 Epigenomics
    2.4 Proteomics
    2.5 Metabolomics
    2.6 Microbiomics
    2.7 Overall Omics Study Design Considerations and Challenges
    References 3: Pain Physiology and the Neurobiology of Nociception
    3.1 Pain Defined
    3.2 Categories of Pain
    3.2.1 Ascending Pain Pathway
    3.2.2 Descending Pain Modulation
    References
    4: Pre-Clinical Models of Pain
    4.1 Reflexive Pain Testing
    4.2 Non-reflexive Pain Testing
    4.3 Disease- or Injury-Specific Pain Models
    4.4 Conclusions
    References
    5: Clinical Pain Phenotyping for Omics Studies
    5.1 Introduction
    5.2 Special Considerations for Omics Studies
    5.3 Pain Phenotyping
    5.3.1 Demographic and Environmental Characteristics
    5.4 Clinical Pain Phenotyping 5.4.1 Diagnostic Criteria
    5.4.2 Self-report Measures
    5.4.3 Controls
    5.5 Psychosocial Phenotyping
    5.5.1 Anxiety
    5.5.2 Depression
    5.5.3 Stress and Mood
    5.5.4 General Symptoms and Somatization
    5.5.5 Catastrophizing and Coping
    5.5.6 Fatigue and Sleep
    5.6 Experimental Pain Phenotyping
    5.6.1 Best Practices for QST Experiments
    5.6.2 Tests of Thermal Sensitivity
    5.6.3 Tests of Mechanical Sensitivity
    5.6.4 Dynamic QST Measures
    5.7 Electronic Phenotyping
    5.8 Summary
    References 6: Genomics of Breast Cancer and Treatment-Related Pain and Comorbid Symptoms
    6.1 Introduction
    6.2 Theoretical Models Used in Cancer Symptom Research
    6.3 Incorporation of Salient Factors in Cancer Symptoms Research
    6.4 Genotypic Studies in Breast Cancer Populations: Focus on Pain
    6.5 Focus on the Psychoneurological Symptom Cluster
    6.6 Additional Considerations of Sex, Race, Ethnicity, and Social Determinants of Health
    6.7 Capturing Changes Over Time: Gene Expression and Epigenomics
    6.8 Conclusions
    References
    7: Low Back Pain
    7.1 Introduction
    7.2 Muscles of the Lower Back.
    Digital Access Springer 2020
  • Digital
    edited by L. María Sierra, Isabel Gaivão.
    Summary: Genotoxicity and DNA Repair: A Practical Approach provides a key reference for determining how to analyze the genotoxic activity of molecules or materials and, at the same time, serves as a useful tool for researchers in the Environmental Mutagenesis and DNA Repair fields. Focused on genotoxicity assays recommended by the "OECD guidelines for the testing of chemicals", this volume also covers other useful assays, such as some gene mutation assays, the comet assay in different species and applications, and the SMART assays of Drosophila. For all the assays, the book presents brief theoretical introductions to the topics and updated standard and modified step-by-step protocols to perform them. Special emphasis is placed on the analysis of nanoparticles, including an integrative approach analysis. The DNA Repair section includes several assays that provide information on repair activity in vitro and in vivo, as well as recent applications to study DNA repair in humans, cell cultures, and animal models. As a volume in the Methods in Pharmacology and Toxicology series, the chapters contain the kind of detail and key implementation advice that ensures reproducible results in the lab.
    Digital Access Springer 2014
  • Digital
    edited by K. N. Nair.
    Contents:
    Taxonomy of Syzygium / Wuu Kuang Soh
    Phylogeny of Syzygium / K.N. Nair and T.S. Rana
    The genus Syzygium in western Ghats / P. Sujanapal and C. Kunhikannan
    Diversity, distribution and life history of Syzygium cumini / Arun Kumar Kushwaha and Lal Babu Chaudhary
    Syzygium cumini in Ayurveda and other traditional medicare systems in India / S. Rajasekharan and Vinodkumar T.G. Nair
    Chemistry of Syzygium cumini / Sudhir Kumar and Rakesh Maurya
    Pharmacognosy and pharmacopoeial standards for Syzygium cumini / Madan Mohan Pandey and Aks Rawat
    Biological activities of Syzygium cumini and allied species / Varughese George and Palpu Pushpangadan
    Cancer immunology of Syzygium cumini / Sabira Mohammed and K.B. Harikumar
    The use of Syzygium cumini in nanotechnology / Avnesh Kumari, Vineet Kumar and Sudesh Kumar Yadav
    Genetic resources of Syzygium cumini in India: present status and management / S.K. Malik, Sanjay Singh, Rekha Chaudhury and Vartika Srivastava
    Horticultural management of Syzygium cumini / S.K. Tewari, Devendra Singh and R.C. Nainwal
    Potential of Syzygium cumini for biocontrol and phytoremediation / S.K. Tewari, R.C. Nainwal and Devendra Singh
    The usage of selected Syzygium species / Roland Hardman.
    Digital Access TandFonline 2017
  • Digital
    Olivier Walusinski.
    Contents:
    Origins and family life
    Education, medical studies, medical practice
    Secretary, colleague, and friend of Jean-Martin Charcot
    The assassination attempt
    Glimpses of Gilles de la Tourette's personality : hospital life and the driout scandal
    Gilles de la Tourette, chief physician for the 1900 World's Fair in Paris
    A sad end : eclipse, twilight, and death
    Doctoral thesis
    Gilles de la Tourette syndrome
    Vibratory medicine and therapeutic suspension techniques
    L'hypnotisme et les états analogues (hypnotism and analogous states)
    Clinical and therapeutic treatise on hysteria : 'hystérie normale'
    Clinical and therapeutic treatise on hysteria : 'paroxysmic hysteria'
    Soeur Jeanne des Anges, supérieure des Ursulines de Loudun (Sister Jeanne of the angels, superior of the Ursuline Convent in Loudun)
    Théophraste Renaudot (1586-1653), Gilles de la Tourette's hero
    Gilles de la Tourette, commentator for la Revue Hebdomadaire, 1892-1900
    Correspondence between Octave Lebesgue, known as Georges Montorgueil, and Gilles de la Tourette
    Gilles de la Tourette, a poet
    Recapitulative list of all Gilles de la Tourette's publications.
    Digital Access Oxford 2019
  • Digital
    David Berrigan, Nathan A. Berger, editors.
    Summary: This volume familiarizes readers with what has now become a very specific research endeavor, Geospatial Factors Impacting Breast Cancer. Cancer occurs in specific places and spaces, each of which have identifiable geographic coordinates, characterized by unique natural, built and social characteristics. These factors contribute significantly to cancer across the spectrum, from etiology through diagnosis, treatment, and outcomes. The book provides important insights into this relatively new and rapidly developing field as a wide-ranging introduction to problems in cancer prevention and control for geographers, demographers and other researchers with a geospatial perspective. Experts share important information for all oncologists, endocrinologists, and behavioral modification professionals to better understand their patients in the context of their environment. The book also outlines important considerations for physicians, scientists, public health professionals and disparity investigators planning clinical trials, community interventions, and community planning.

    Contents:
    Part One
    Overview and Spatial Methods
    Chapter 1: Connecting Population, Health and Place (With Geospatial Tools and Data)
    Chapter 2: Analyzing cancer and breast cancer in space and time
    Chapter 3: Creating Maps and Mapping Systems for Cancer Control and Prevention
    Chapter 4: Physical Activity and Exposure in Breast Cancer Survivors Using GPS, GIS, and Accelerometry
    Chapter 5: Towards Systematic Methods in an Era of Big Data: Neighborhood Wide Association Studies
    Chapter 6: Geospatial Approaches to Environmental Determinants of Breast Cancer in the California Teachers Study
    Chapter 7: Systematic Review of Geospatial Approaches to Breast Cancer Epidemiology
    Part Two
    Environment and Context
    Chapter 8: Studying the Influence of the Neighborhood Obesogenic Environment on Breast Cancer in Epidemiological Cohorts: the Multiethnic Cohort
    Chapter 9: Spatial analyses of Environmental Exposures and Breast Cancer: Natural Vegetation, Ambient Air Pollution and Outdoor Light at Night as Examples
    Chapter 10: Neighborhoods and Breast Cancer Survival: The Case for an Archetype Approach
    Chapter 11: Environmental Modification of Adult Weight Loss, Physical Activity, and Diet Intervention Effects
    Part Three
    Screening, Diagnosis and Beyond
    Chapter 12: Geographic Influences on Screening Mammography
    Chapter 13: Spatial and Contextual Analyses of Stage at Diagnosis
    Chapter 14: Geographic Variation in Medical Neighborhoods for Breast Cancer Care: Diagnosis and Beyond
    Part Four
    Cross-cutting Topics
    Chapter 15: Persistent racial disparities in breast cancer mortality between Black and White women: what SR
    Chapter 16: Rural-Urban Disparities in Breast Cancer: Six Suppositions and Future Directions
    Chapter 17: Microenvironmental Influences on Team Performance in Cancer Care
    Chapter 18: Opportunities and Challenges in Geospatial Approaches to Breast Cancer Prevention and Control
    Index.
    Digital Access Springer 2019
  • Digital
    Parakrama T. Chandrasoma.
    Summary: GERD: A New Understanding of Pathology, Pathophysiology, and Treatment transforms the assessment of gastroesophageal reflux disease (GERD) from its present state, which is largely dependent on clinical definition and management, to a more objective scientific basis that depends on pathologic assessment. Sequential chapters in this single-author book describe the fetal development of the esophagus, the normal adult state, and the way exposure to gastric juice causes epithelial and lower esophageal sphincter damage at a cellular level. It allows recognition of the pathologic manifestations of lower esophageal sphincter damage and develops new histopathologic criteria for quantitating such damage. This understanding provides new pathologic criteria for definition and diagnosis of GERD from its earliest cellular stage. Algorithms based on measurement of sphincter damage can identify, even before the onset of clinical GERD, persons who will never develop GERD during life, those who develop GERD but remain with mild and easily controlled disease, and those who will progress to severe GERD with failure to control symptoms, Barrett esophagus and adenocarcinoma. Aggressive early intervention in the last group with the objective of preventing disease progression to its end points of uncontrolled symptoms and adenocarcinoma becomes feasible.

    Contents:
    Definition of gastroesophageal reflux disease
    Present diagnosis and management of gastroesophageal and reflux disease
    Fetal and postnatal development of the esophagus and proximal stomach
    Histologic definition and diagnosis of epithelia in the esophagus and proximal stomach
    Definition of the normal state
    Definition of the gastroesophageal junction
    The normal lower esophageal sphincter
    The pathogenesis of early GERD
    Correlation of LES damage and GERD
    The effect of damage to the abdominal segement of the LES
    Columnar-lined esophagus
    Esophageal adenocarcinoma
    Progression of GERD at the clinical level
    Progression of GERD at a pathological level
    Molecular evolution of esophageal epithelial metaplasia
    Progression of GERD from the perspective of LES damage
    New pathologic test of LES damage
    New method of functional assessment of the LES
    Prediction of future progression of LES damage
    Proof of cencept of the new diagnostic method
    Application of the new method to present and future management of GERD.
    Digital Access ScienceDirect 2018
  • Digital
    Nages Nagaratnam, Kujan Nagaratnam, Gary Cheuk.
    Summary: This volume provides a comprehensive overview of the unique clinical entities of diseases in older patients. The book arranges the organ systems in 21 sections, which include over 100 collective chapters on various age-related diseases in these organ systems. The text is specifically designed for ease-of-use and include learning tools that include multiple choice, short answer, and extended matching questions, case vignettes, self-assessments, and rich tables and illustrations. Each section includes a review of the anatomy, physiology and pathology that are specific to aging patients. The text covers the complex factors that present diagnosis challenges, including the interaction of the disease process with co-existing morbidities, aged- related physiological changes and pre-existing functional challenges and psychosocial circumstances. The text also works with the previously published text Diseases in the Elderly: Age-Related Changes and Pathophysiology, which is tailored to complement this resource. Written by experts in the field, Geriatric Diseases: Clinical Expression, Management and Impact is the ultimate guide on clinical expression and management of diseases in the elderly for medical students, residents, fellows, geriatricians, gerontologists, primary care physicians, internal medicine specialists, emergency room physicians, specialist nurses, and all other physicians and medical professionals treating older patients.

    Contents:
    Introduction to cardiovascular disease
    Cardiac failure in the elderly
    Cardiac arrhythmias in the elderly
    Infective endocarditis in the elderly
    Coronary heart disease in the elderly
    Valvular heart disease in the elderly
    Hypertension in the elderly
    Peripheral arterial disease in the elderly
    Introduction to respiratory diseases
    Pneumonia in the elderly
    Chronic obstructive airway disease
    Chronic asthma
    Carcinoma of the lung
    Pulmonary embolism
    Introduction to the gastrointestinal system
    Oesophagus and oesophageal disorders
    Peptic ulcer
    Colorectal cancer
    Inflammatory bowel disease in older adults
    Introduction to the hepato-biliary system
    Viral hepatitis in the elderly
    Chronic liver disease in the elderly
    Ascites in the elderly
    Obstructive jaundice in the elderly
    Introduction to blood disorders
    The Anaemias
    Haematological neoplastic disorders
    Introduction to renal and lower urinary tract disorders
    Glomerular disease in the elderly
    Renovascular disease
    Acute renal failure
    Chronic renal failure
    Prostate gland and related disorders
    Sexuality sexual dysfunction in the elderly
    Introduction to chronic neurological disorders
    Pasrkinson’s disease,Secondary Parkinsons and Parkinson plus syndromes
    Multisystem atrophy
    Amyotrophic lateral sclerosis
    Multiple sclerosis
    Polyneuropathy
    Epilepsy in the elderly
    Disorders in neuromuscular transmission
    Introduction to metabolic bone disorders
    Osteoporosis
    Osteomalacia
    Osteoporotic fractures and management
    Paget’s disease
    Introduction to endocrine disorders
    Diabetes Mellitus
    Thyroid disorders
    Hyperparathyroidism
    Introduction to electrolyte and mineral metabolism disorders
    Sodium metabolism
    Potassium metabolism
    Calcium metabolism
    Introduction to the musculo-skeletal system
    Neck pain (Cervical)
    Low back pain (Lumbosacral)
    Shoulder pain
    Hip pain
    Knee pain
    Introduction to arthritides
    Rheumatoid Arthritis
    Polymyalgia Rheumatica
    Psoriatic arthropathy
    Osteoarthritis
    Crystal induced arthritis
    Vasculitis
    General considerations
    Systemic lupus erythematosus
    Systemic sclerosis
    Sjogren’s syndrome
    Overlap syndromes
    Introduction to organic brain disorders
    Anatomical and physiological changes with aging-Brain
    Acute confusional state
    Chronic organic disorders-Dementias
    General considerations
    Neurodegenerative dementias
    Vascular dementias
    Symptomatic dementias
    Behavioural and psychological symptoms of demented (BPSD)
    Drug management of dementias
    Mild Cognitive Impairment
    Introduction to psychiatry and functional disorders
    Mood disorders (Major depression, bipolar disorders)
    Anxiety and Anxiety disorders
    Paranoia in the elderly
    Substance abuse
    Suicide in the elderly
    Introduction to cerebrovascular disease
    Stroke in the elderly
    Diagnosis management and complications
    Transient Ischaemic Attack (TIA)
    Long term sequel post-stroke
    Prevention of stroke
    General considerations
    Anatomy of the ear
    Common ear problems in the elderly
    Vertigo/dizziness in the elderly
    Tinnitus
    Introduction to vision care
    Anatomy of the eye
    Common eye problems in the elderly
    Blurred vision
    Dry eye
    Red eye
    Introduction to skin diseases
    Anatomy and physiology of the skin
    Common skin diseases in the elderly
    Parasitosis
    Pruritis in the elderly
    Introduction to oral care
    Anatomy of the tooth
    Oral issues in the elderly
    Related disorders
    Oral manifestations of system disease.
    Digital Access Springer 2018
  • Digital
    Iona Murdoch, Sarah Turpin, Bree Johnston, Alasdair MacLullich, Eve Losman.
    Contents:
    Introduction to geriatric emergency medicine
    Essentials of assessment and management in geriatric emergency medicine
    Special skills in geriatric emergency medicine
    Vulnerable adults and elder abuse
    Chest pain and atrial fibrillation
    Dyspnoea
    Infection and sepsis
    Falls and immobility
    Syncope
    Dizziness
    Major trauma
    Fractures and back pain
    Skin trauma
    Head injury
    Abdominal emergencies
    Diabetic and environmental emergencies
    Acute kidney injury and metabolic emergencies
    Delirium
    Stroke and transient ischaemic attack.
    Digital Access Wiley 2015
  • Digital
    Lee A. Lindquist, Scott M. Dresden, editors.
    Summary: This book introduces the unique medical needs of aging patients in the emergency department and outlines the challenges that leave many clinicians struggling to adequately care for this demographic, including limited resources, management concerns, and other barriers. The text presents strategies for screening, diagnosing, and treating geriatric syndromes seen in the emergency care of the older adult patient. Topics include pharmacological interventions, transitioning care, and sustainability. The text includes complex cases that demonstrate the caution necessary to treat this delicate patient group. Each case concludes with a set of concise "take-home points" to make the guidelines easy to remember and/or reference. Geriatric Emergencies: A Case-Based Approach to Improving the Acute Care of Seniors is an excellent resource for geriatricians, emergency medicine specialists, internal medicine physicians, hospitalists, nurses, social workers, students, residents, trainees, and all medical professionals working with older patients in an emergency setting.

    Contents:
    Growing Older in the Emergency Department
    Components of an effective Geriatric Emergency Department
    Cognitive Impairment in the ED
    Syncope in a rural emergency department setting
    ER referrals and hospitalizations from Post-Acute and Long-Term Care Facilities
    Can Home Visits Make a Difference to Emergency Department Visits? "I will just stop by his place on the way home: Who knew it would be a journey?"
    Medication Errors in Aging Adults: A Case-Based Approach to Medication Management
    Pain, Opioid Use, and Palliative Care of Older Adults in the Emergency Department
    Acute Mental Status Changes and Over-the-Counter Medications in Older Adults
    Identifying fall risk in the Emergency Department
    Capacity, Advanced Planning, and Buying Time.
    Digital Access Springer 2019
  • Digital
    edited by Amal Mattu, Shamai A. Grossman, Peter L. Rosen.
    Digital Access Wiley 2016
  • Digital
    edited by Kim A. Collins, Roger W. Byard.
    Summary: "A major historical impediment to the study of the diseases of the elderly has been the relative lack of elderly patients. For much of our history, human populations have been characterized by high fertility and high infant and child mortality. Those who did survive to adulthood died at high rates (compared to modern standards) of either natural disease or violence. Reaching old age was considered an achievement. Displayed graphically, this population dynamic resulted in a characteristic bottom-heavy population pyramid with lots of infants born, lots of infants and children dying, and a sharp taper to a narrow peak of the very elderly"-- Provided by publisher.

    Contents:
    A history of geriatric medicine and geriatric path / Sanchez
    Pathophysiology of ageing / Ibrahim
    Medicolegal investigation of elder maltreatment and deaths / Howe
    The autopsy / Schandl
    Fatal & non-fatal accidents / Payne-James
    Euthanasia / Stephen Cordner
    Starvation, dehydration, malnutrition, and neglect / Burkhard Madea, Elke Doberentz
    Physical abuse and elder homicide / Kim A. Collins and Rebekah Jaques
    The ageing foot
    forensic considerations / Jones
    Forensic entomology / Jeffery K. Tomberlin, Jonathan A. Cammack, Lauren M. Weidner, and Robert T. Puckett
    Non-lethal elder abuse / Alex K Williamson
    Sexual assault in the elderly / Dayman
    Hypothermia and Hyperthermia in the Geriatric Population / Christopher M. Milroy and Jacqueline L. Parai
    Suicide and social isolation In elders / Roger W. Byard
    Cardiovascular diseases in the elderly / Stephen D Cohle and Dylan V. Miller-Lungs / Anja C. Roden
    Infectious conditions and the immune system in elderly / Warner
    Neurodegenerative diseases in the elder / Ross R. Reichard, Barbara J. Crain, and Linda Iles
    Other neurological conditions and age-related changes / Iles and Crain
    Genitourinary conditions / Georgia Aitken, Noha Ferrah, Janaka Lovell, Tamsin Santos, Nicola Cunningham, and Joseph Elias Ibrahim
    The elder organ and tissue donor / Kim A. Collins, Dilhani Amarasinghe, and Muditha Amarasinghe
    Conditions in gastrointestinal tract / Xuchen Zhang and Dhanpat Jain
    Hematologic conditions / R.M. Wright, M.F. Cole-Sinclair, and J.E. Ibrahim
    The oral cavity of the elder / Kim A. Collins and Paige J. Collins
    The anthropology of aging / S. Blau
    Endocrinology and diabetes / David Levy
    Geriatric toxicology / Laura M. Labay
    Cardiopulmonary resuscitation related injuries in elders / Kim A. Collins
    Imaging of elders / Amma N. Maurer, Anousheh Sayah, Juan M. Coca Guzman, and Angela D. Levy
    The 'virtual autopsy' and special radiographic applications / Noel Woodford, Chris O'Donnell, Matthew Lynch
    Iatrogenic deaths / Joseph A. Prahlow
    Residential care facility deaths / Joyce Lynn deJong-Monroe
    Morbid obesity and frailty / Roger W. Byard
    Ancillary testing and special dissections / Mary Ann Sens and Richard Conran
    The legal regulation of the consequences of aging / Freckelton
    Death certification / Cynthia A. Schandl.
    Digital Access Cambridge 2020
  • Digital
    C.S. Pitchumoni, T.S. Dharmarajan, editors.
    Summary: Aging trends in the United States and Europe continue to demonstrate an increasingly older society, a trend that is unlikely to change for decades to come. This trend renders it prudent for health care providers to better prepare for the changes in society and their health needs. The current number of older adults (aged over 65), about 13% of the U.S. population, is expected to grow to over 20% in the next 20 years. Preparation for the changes in society involves provision of training for current and future generations of physicians to deal with health problems of older adults. Training programs in internal medicine and gastroenterology are required to deal with disorders of aging in the present day hospitalized, long-term care and community older adults. Physiological changes and disease processes in older adults differ significantly from those of the young; these are aspects that trainees and practicing physicians need to have an understanding of. Yet texts devoted to gastrointestinal illness in the elderly are scant at this stage and are clearly in demand. This text provides a comprehensive overview of gastrointestinal disease and disorders in older adults. Divided into sixteen sections, this major reference work covers all aspects of gastroenterology as it pertains to older adults, including epidemiology, gastrointestinal physiology, motility disorders, luminal disorders, hepatobiliary disease, systemic manifestations, neoplastic disorders, gastrointestinal bleeding, and gastrointestinal cancer. In addition to fully revised chapters from the previous edition of Geriatric Gastroenterology, the latest edition features new chapters on drug injury to the GI tract, gut microbiota and aging, dysphagia, diabetes and its manifestations, and nursing for GI disorders. Nutrition and related disorders, as well as capsule endoscopy and its utility in the geriatric population, are also highlighted in the text. Presented in a simple, easy to read format, the volume includes numerous figures, tables, and key points to enable ease of understanding.

    Contents:
    Geriatric Gastroenterology: the Geriatrician's Perspective
    Geriatric Gastroenterology: The gastroenterologist's perspective
    Geriatric gastroenterology: future trends
    The Physiology of Aging
    The Gastrointestinal System and Aging
    Epidemiology of Gastrointestinal disease
    Comprehensive Geriatric Assessment
    Drug effects on the gastrointestinal tract
    Pharmacokinetics of aging
    Drug-nutrient interactions
    Probiotics
    Geriatric Nutritional assessment
    Tube feeding: techniques and procedure
    Enteral and Parenteral nutrition
    Ethical aspects, expectations and outcomes associated with PEG in Dementia
    Water, Potassium, Sodium, and Chloride in Nutrition
    Intravenous Fluid Administration
    B12 and Folic acid
    Iron, copper and zinc
    Vitamin D and calcium
    Dietary Fiber in Health and Disease
    Healthy Diet for the Older adult
    Endoscopy in Older Adults: Risks, benefits, considerations
    Wireless capsule endoscopy
    Gastrointestinal Radiology
    Advanced Imaging of Geriatric Gastrointestinal Pathology
    Laboratory tests in Older Adults: Indications, Interpretations, Issues
    Gastrointestinal Pathology in the Older Adult
    Dysphagia
    Gastroparesis in older adults
    Esophageal Reflux disease and its Complications
    Abdominal pain
    Intestinal Gas
    Constipation
    Diarrhea
    Upper and Lower Gastrointestinal Bleeding
    Liver function tests and interpretation
    Viral Liver Diseases
    Tumors of the liver
    Non-alcoholic Fatty Liver Disease (NAFLD) and Non-alcoholic Steatohepatitis (NASH)
    Drug induced liver injury
    Gall bladder disease
    Acute Pancreatitis
    Chronic Pancreatitis
    Oral health in Older Adults
    Small intestinal bacterial overgrowth syndrome
    Peptic ulcer
    Irritable bowel syndrome
    Intestinal ischemia
    Inflammatory bowel disease
    Non-IBD and Non-Infectious colitis
    Celiac disease
    Diverticular disease
    Clostridium Difficile Associated Diseases
    Gastrointestinal Infections
    Anal Incontinence
    Rectal prolapse
    Colorectal Cancer Screening In The Older Adult: A Case Based Approach
    Gastrointestinal polyps
    Gastric neoplasms
    Esophageal cancer
    Pancreatic cancer
    Colorectal cancer
    Palliative Care of GI issues at the End of Life
    The Surgical Abdomen
    Colostomy and Ileostomy care
    Gastrointestinal and Hepatic Manifestations of Systemic Diseases
    Abdominal aortic aneurysm
    Rheumatological manifestations of Gastrointestinal Disease
    Mucocutaneous manifestations with Gastrointestinal disease
    HIV disease
    Gastrointestinal Disorders in the Older Adult: the Psychiatrist's Role
    Nursing aspects for GI disorders
    Diabetes and manifestations in the old
    Imaging of GI disorders, case based
    Anemia of GI origin
    Mesenteric ischemia
    Anticoagulation in relation to GI disorders
    Gut microbiota and aging
    Drug injury to the gastrointestinal tract
    NPO: benefits and consequences
    Dysphagia
    Anorexia of aging
    Colonic pseudo-obstruction.
    Digital Access Springer 2021
  • Digital
    Nicholas C. Danford, Justin K. Greisberg, Charles M. Jobin, Melvin P. Rosenwasser, Marcella D. Walker, editors.
    Summary: The global burden of geriatric hip fractures is enormous. From both the patient's and physician's perspective, the injury is complex. A hip fracture often changes a patient's life and/or the life of the patient's family permanently. From the physician's perspective, care of geriatric hip fracture patients requires a multidisciplinary team, which is led by the surgeon and which includes internists and other subspecialists within internal medicine, anesthesiologists, nurses, operating room technicians, social workers, physical therapists, and rehabilitation center coordinators and staff. Nowhere in the orthopedic literature is there a text that guides care for these complex patients from injury through recovery. This text is the first to do so by organizing and synthesizing a large body of literature. Its main themes include pre-operative, operative, and post-operative care of the patient who sustains a geriatric hip fracture. Its main objective is to organize the current body of literature into a cohesive whole so that the busy orthopedic surgeon does not have to undertake a literature search each time he or she wants an answer to the myriad questions that characterize a patient's injury, treatment, and recovery course. With regard to pedagogy, because orthopedic surgeons in training will utilize this book, and because the case study is the central pedagogical tool in the field of orthopedic surgery, this book includes case studies within each chapter, with the author's preferred treatment and decision-making rationale for each case. Selected video supplements reinforce real-world application of knowledge. Practicing orthopedic surgeons, as well as orthopedic residents and fellows in training, will find Geriatric Hip Fractures: A Practical Approach a highly useful and informative resource.

    Contents:
    Introduction: History of Geriatric Hip Fracture Treatment
    Initial Workup, Diagnosis, and Fracture Classification for Geriatric Hip Fractures
    Peri-operative Medical Co-management of Patients with Geriatric Hip Fractures
    Applied Anatomy for Treatment of Geriatric Hip Fractures
    Surgical Treatment of Peritrochanteric Hip Fractures
    Surgical Treatment of Femoral Neck Fractures
    Periprosthetic Femur Fractures after Total Hip Arthroplasty
    Pathologic Hip Fractures in the Geriatric Patient
    Outcome Assessment and Quality Improvement for Geriatric Hip Fractures
    Rehabilitation After Geriatric Hip Fractures
    Post-Operative Bone Mineral Health Optimization in the Geriatric Patient
    Geriatric Hip Fracture Care in Low- and Middle-Income Countries
    Geriatric Hip Fractures: Economics of Care.
    Digital Access Springer 2021
  • Digital
    Jennifer L. Hayashi, Bruce Leff, editors ; Linda DeCherrie, Theresa A. Soriano, associate editors.
    Summary: This book is a practical reference for any clinician who has struggled to care for an older adult in a home setting. The volume is written by experts in the field who describe fundamental principles and clinical approaches of geriatric home-based care and their application to specific diseases and conditions, including delirium, incontinence, falls, and chronic pain and disability. The book also details house calls for special populations, from the developmentally disabled to those afflicted with neurologic or psychiatric diseases. The volume explores house calls within the context of the US healthcare system. Geriatric Home-Based Medical Care: Principles and Practice is a valuable resource for geriatricians, geriatric nurses, primary care physicians, social workers, public health officials, and all medical professions who need tools to provide timely, compassionate, and high-quality care for their older adult patients.

    Contents:
    Introduction: Why house calls medicine?
    Myths and pitfalls
    Getting started with house calls (with reference to AAHCM guide)
    How to make a house call
    Handling common clinical situations in the home
    House calls for special populations
    Advance care planning for house calls patients
    Locations
    Working with community resources critical to house calls
    Conclusion: rationale, scope, impact of house calls.
    Digital Access Springer 2016
  • Digital
    edited by Robert P. Roca, Micheline Dugué, Maria D. Llorente.
    Summary: "Geriatric Mental Health Care addresses the disproportionate impact that the COVID-19 pandemic has had on older adults with mental illness. Topics covered include inpatient geriatric psychiatry during a pandemic, telehealth models of care, health care staff concerns, and social determinants of health. The authors also explore the pandemic's effects on research and the economy, analyzing the impact of nonclinical factors on the broader clinical care effort. Geriatric Mental Health Care provides techniques that health care providers can use to overcome the challenges of the current pandemic and prepare for the next one"-- Provided by publisher.

    Contents:
    Pandemics and Mental Health : Epidemiology and Public Health. / Joshua C. Morganstein, M.D., Holly B. Herberman Mash, Ph.D., Madeline B. Teisberg, D.O., Shannon C. Ford, M.D., Carol S. Fullerton, Ph.D., Robert J. Ursano, M.D.
    Historical Overview of Pandemics / Matthew Louis Edwards, M.D., Yolonda Pickett, M.D., Maria D. Llorente, M.D., FAPA
    Emergency Psychiatric Care for Older Adults During the COVID-19 Pandemic : Workflow, Common Presentations, and Overall Trends / Dwight Kemp, M.D., M.S., Neha N. Sharma, M.D., Alan Akira, M.D., Eitan Z. Kimchi, M.D.
    Inpatient Geriatric Psychiatry During a Global Pandemic. / Antoinette M. Valenti, M.D., Ebony Dix, M.D., Col. (Ret.) Elspeth Cameron Ritchie, M.D., M.P.H.,
    Geriatric Mental Health Care : Lessons From a Pandemic / Marc Agronin, M.D., DFAPA, DFAAGP
    Dementia Care and the COVID-19 Pandemic / Mari Umpierre, Ph.D., LCSW, Shehan Chin, LMSW, Karla Steinberg, LMSW, Micheline Dugué, M.D.
    Telehealth Models of Care for Geriatric Behavioral Health During a Pandemic / Magdalena Bednarczyk, M.D., Donald M. Hilty, M.D., M.B.A.
    Shilpa Srinavasan, M.D., DFAPA, DFAAGP, Sandra Swantek, M.D., FAPA
    Managing Health Care Staff Concerns During Pandemics : Acute Phase and Recovery Phase / Jonathan M. DePierro, Ph.D., Laura Bevilacqua, M.D., Ph.D.
    Geriatric Psychiatry Among Older Adults From Diverse Backgrounds in the Age of COVID-19 / Rita Hargrave, M.D., FAPA, Sharwat Jahan, M.D., Kanya Nesbeth, M.D., Yee Xiong, M.D., Maria D. Llorente, M.D., FAPA
    Social Determinants of COVID-19 Morbidity and Mortality / Linda Nix, M.D, M.P.H., Emily Tan, B.A., Nhi-Ha Trinh, M.D., M.P.H., Iqbal "Ike" Ahmed, M.D., FRCPsych (UK)
    The Effect of COVID-19 on Research : Tales From a Pandemic / Maria Loizos, Ph.D., Judith Neugroschl, M.D.
    Social Isolation and Loneliness in Older Adults During the COVID-19 Pandemic ./ Susan W. Lehmann, M.D., Mari Umpierre, Ph.D., LCSW, Shehan Chin, LMSW, Janet Baek, M.D.
    The COVID-19 Economy : Mental Health Impact on Older Adults / Sarah E. LaFave, Ph.D., M.P.H., R.N., Robert P. Roca, M.D., M.P.H., M.B.A.
    Ethical Dilemmas and Resource Scarcities During Pandemics : Geriatric Mental Health Care : Lessons From a Pandemic. / Marilyn Price, M.D., Donna M. Norris, M.D., Samara E. Rainey, B.A., Raya E. Kheirbek, M.D., M.P.H.
    Neuropsychiatric Manifestations of COVID-19 / Rebecca Grossman-Kahn, M.D., O. Joseph Bienvenu, M.D., Ph.D.
    Psychopharmacological Challenges of Treating Older Adults With COVID-19 / Badr Ratnakaran, M.B.B.S., Daniel C. Dahl, M.D.
    Challenging Times : Consultation-Liaison Psychiatry in the Era of COVID-19 / Farah Tabaja, M.D., Paul B. Hill, M.D.
    Digital Access
    Provider
    Version
    PsychiatryOnline
    ProQuest Ebook Central
  • Digital
    edited by Anil K. Nair and Marwan N. Sabbagh.
    Contents:
    Part 1. The aging brain in neurology
    part 2. Assessment of the geriatric neurology patient
    part 3. Neurologic conditions in the elderly
    part 4. Therapeutics for the geriatric neurology patient
    part 5. Important management issues beyond therapeutics in the geriatric neurology patient.
    Digital Access Wiley 2014
  • Digital
    edited by Steven T. Dekosky, Sanjay Asthana.
    Digital Access ScienceDirect 2019
  • Digital
    Jamie W. Smith, Bradley J. Goad.
    Summary: "Geriatric Notes is an essential quick reference for the advanced practice provider (APP) who provides care to elders in the outpatient setting, such as nursing homes, family practice, or home health. With a practical, accessible, and concise approach, it offers an easy to understand overview of the most common diagnoses, topics, and symptoms encountered in the aging population. Designed to offer access to the basics, this guide provides tables and bullet points for easy reference. Sections include health promotion, neurology and psychiatry, cardiovascular, pulmonary, gastroenterology, genitourinary, rheumatology, dermatology, endocrinology, labs and imagery, Beers list, and common presentations"--Provided by publisher

    Contents:
    Machine generated contents note: Section I Prevention & health promotion
    Section II Neurology & psychiatry
    SectionIII Cardiovascular
    Section IV Pulmonary
    Section V Gastroenterology
    Section VI Genitourinary
    Section VII Rheumatology
    Section VIII Dermatology
    Section IX Endocrinology
    Section X Labs and imaging
    Section XI Beers list
    Section XII Common presentations
    Section XIII Topics of discussion.
    Digital Access R2Library 2019
  • Digital
    Martine Extermann, editor.
    Summary: This book is intended as a comprehensive resource for clinicians and researchers seeking in-depth information on geriatric oncology. The coverage encompasses epidemiology, the biology and (patho)physiology of aging and cancer, geriatric assessment and management, hematologic malignancies, solid tumors, issues in patient care, and research methods. Since cancer is a disease of aging and people are living longer, most cancer patients are now aged 70 and older. Yet the more we age, the more diverse we become in terms of our health, biologic fitness, and cancer behavior. Typically, however, general oncology clinical trials address only a selected healthier and younger population of patients. Geriatric oncology is the area of oncology that addresses these issues but while a wealth of knowledge has been accumulated, information is often difficult to retrieve or insufficiently detailed. The SpringerReference program, in which this book is published, offers an ideal format for overcoming these limitations since it combines thorough coverage with access to living editions constantly updated chapter by chapter via a dynamic peer-review process, ensuring that information remains current and pertinent.
    Digital Access Springer 2020
  • Digital
    Hilary A. Beaver, Andrew G. Lee, editors.
    Summary: Geriatric patients have unique responses to treatment and disease, often harboring co-morbidities that can impact evaluation, treatment, and prognosis, which can require specialized expertise or experience. Geriatric Ophthalmology, Second Edition draws upon the successful first edition by applying a competency-based approach to these patients, improving awareness, increasing understanding, and encouraging expertise about geriatric issues among eye care professionals. These intersecting conditions and their treatment are comprehensively discussed in this fully updated second edition, complete with additional high-quality illustrations and photos. Each chapter utilizes illustrative cases to exemplify the points of care encompassed by the competencies. Topics of special interest are included, such as diabetic retinopathy, age-related macular degeneration, cataracts, glaucoma, diabetic retinopathy, low vision, all diseases of aging, and the effect of vision loss on the geriatric patient’s quality of life. Medical students, residents, fellows, clinicians, and allied health personnel alike will find this to be a comprehensive resource and exceptional guide to the care of older patients with geriatric ophthalmology problems.
    Digital Access Springer 2019
  • Digital
    [edited by] Robert T. Sataloff, Michael M. Johns III, Karen M. Kost.
    Contents:
    The science of aging / Alessandro Bitto, Chad A. Lerner, and Christian Sell
    Geriatric otolaryngology : an overview / Karen M. Kost
    Understanding geriatric syndromes, the geriatric interdisciplinary team, and resources to optimize care for older patients / Sarah H. Kagan
    Evaluation of the outpatient geriatric patient / David Eibling
    Operative evaluation of the geriatric patient / Natalie Justicz and Jeanne Hatcher
    Age-related hearing loss / Kourosh Parham, Frank R. Lin, and Brian W. Blakley
    Regenerative therapies for sensorineural hearing loss : current research implications for future treatment / Cynthia L. Chow and Samuel P. Gubbels
    Hearing aids : considerations in the geriatric population / Amanda Kantor, Erica Miele, John Luckhurst, Mary Hawkshaw, and Robert T. Sataloff
    Cochlear implantation in the elderly / Daniel H. Coelho and Brian J. McKinnon
    Subjective idiopathic tinnitus in the geriatric population / Paul F. Shea and Brian J. McKinnon
    Dizziness, imbalance, and age-related vestibular loss in the geriatric population / Yuri Agrawal, Allan Rubin, and Stephen J. Wetmore
    Sinonasal disease in the elderly / David R. Edelstein
    Taste and smell in the elderly / Richard L. Doty and Hussam Tallab
    Inhalant allergies and asthma in the geriatric population / Karen H. Calhoun
    Voice disorders in the elderly / Robert T. Sataloff and Karen M. Kost
    Swallowing disorders in the elderly / Ozlem E. Tulunay-Ugur
    Sleep disturbance in the geriatric population / Christopher G. Larsen and M. Boyd Gillespie
    Facial plastic surgery in geriatric patients / J. Regan Thomas
    Oral cavity disorders in geriatric patients / Elliot Regenbogen and Denise A. Trochesset
    Advanced cutaneous malignancies in the elderly / Kelly Michele Malloy and Chaz L. Stucken
    Head and neck cancer in the elderly / Mihir R. Patel, Raymond L. Chai, and Ara A. Chalian
    The role of neuropsychology in the evaluation and treatment of geriatric patients / Thomas Swirsky-Sacchetti and Caterina B. Mosti.
    Digital Access
    Provider
    Version
    Thieme-Connect
    Thieme MedOne Otolaryngology
  • Digital
    editor, William Staples.
    Summary: The most definitive, balanced case-based guide to effectively managing geriatric disorders. The definitive case-based guide to effectively managing geriatric disorders Geriatric Physical Therapy provides the most authoritative overview available on managing the special needs of the elderly in all health care settings. Through nearly 200 cases, the text offers a skill-building balance of theory and clinical application of knowledge in caring for the older adult population. This timely book addresses and incorporates aspects of prevention, fitness, and wellness into the rehabilitative model of care for elders with and without pathological conditions. Features:Nearly 200 cases examine both acute and chronic stage settings, and provides suggested tests and measures. Cases focus on orthopedics and neurology for consistency with board exams, which concentrate in these therapeutic areas Tables and boxes organize and summarize important information and highlight key points for quick reference A well-referenced and scientific approach provides the depth to understand integral processes and procedures Each case in Geriatric Physical Therapy is designed to help you learn how to apply geriatric physical therapy concepts to specific patient situations. The cases are presented in a consistent manner?similar to what you would see in a clinical setting?and focus on one primary topic or problem. Chapters open with a brief overview of the topic, which reviews basic information on that topic, followed by related cases. Excellent pedagogy includes board-type review questions and chapter summaries that conclude each chapter.

    Contents:
    Musculoskeletal cases
    Neuromuscular cases
    Cardiovascular and pulmonary cases
    Integumentary cases
    Medically complex cases
    Other geriatric issues.
    Digital Access AccessPhysiotherapy 2016
  • Digital
    editor, William H. Staples ; section editors, Jill Heitzman, Meri Goehring, Deborah A. Kegelmeyer, William H. Staples.
    Summary: "This text is designed to be utilized as an adjunct throughout a doctor of physical therapy curriculum. The cases have all been updated with additional questions and references added. Many new cases have also been added. This text can be used with a general pathology course; an aging, lifespan, or gerontology (geriatric physical therapy) course. This text can also be a helpful study guide for the licensing examination, and even the geriatric specialty examination." -- Preface

    Contents:
    Introduction to geriatric physical therapy
    Musculoskeletal cases
    Neuromuscular cases
    Cardiovascular and pulmonary cases
    Integumentary cases
    Complex medical problems in the older adult
    Other important issues for the aging adult.
    Digital Access
    Provider
    Version
    AccessPhysiotherapy
    AccessPhysiotherapy
  • Digital
    edited by Audrey Chun.
    Summary: This book serves as a comprehensive reference for the basic principles of caring for older adults, directly corresponding to the key competencies for medical student and residents. These competencies are covered in 10 sections, each with chapters that target the skills and knowledge necessary for achieving competency. Each of the 45 chapters follow a consistent format for ease of use, beginning with an introduction to the associated competency and concluding with the most salient points for mastery. Chapters also includes brief cases to provide context to the clinical reasoning behind the competency, strengthening the core understanding necessary to physicians of the future. Written by expert educators and clinicians in geriatric medicine, Geriatric Practice is key resource for students in geriatric medicine, family and internal medicine, specialties, hospice and nursing home training, and all clinicians studying to work with aging patients.

    Contents:
    History and Trends
    Identifying the Unique Needs of the Aging Population
    Education of Current and Future Providers
    Physiology of Aging
    Normal vs. Abnormal Physical Exam
    Testing in the Elderly
    Differential Diagnoses in the Setting of Advanced Age and Multiple Conditions
    Common Acute Illness
    Patient-Centered Care for Persons with Multiple Conditions
    Geriatric Pre-Operative Evaluation of the Older Adult
    Common Chronic Conditions
    Geriatric Considerations in Common Surgical Conditions
    Prescription Selection and Dosing
    High-Risk Prescriptions for Aging Patients
    Dietary Botanicals and Supplements
    Understanding the Medication List and Addressing Polypharmacy in Older Adults
    Depression in Older Adults: Principles of Diagnosis and Management
    Behavioral and Psychiatric Symptoms in Dementia (BPSD)
    Diagnosis and Management of Delirium
    Assessment of Memory and Function
    Non-pharmacologic Management of BPSD: Agitation and Behavioral Problems in Dementia
    Assessment of Capability and Capacit
    Developing a Management Plan Safety and Risk Assessment
    Falls Screening, Differential Diagnosis, Evaluation, and Treatment
    Driving
    Individualized Decision-Making for Preventive Medicine in Older Adults
    Advance Care Planning for Older Adults
    Patient Preference, Prognosis, and Decision-Making in Screening and Treatment
    Sites of Care for the Older Adult
    Hospice, Clinic and Home-based Care
    Acute Care in the Home Setting: Hospital at Home
    Hazards of Hospitalization
    Prevention of the Hazards of Hospitalization
    Managing Medications and Addressing Polypharmacy
    Foley Catheter Use and Management of Urinary Symptoms
    High-Risk Pressure Ulcers
    Discharge Planning
    Interprofessional Care: Why Teamwork Matters
    Chronic Care Management
    Registries/Data in Population Health Management
    Management of Pain Symptoms
    Non-Pain Symptoms
    Psychosocial, Social, and Spiritual Needs of Geriatric Patients
    Introduction to Palliative Care.
    Digital Access Springer 2020
  • Digital
    Ana Hategan, James A. Bourgeois, Calvin H. Hirsch, Caroline Giroux, editors.
    Contents:
    I: Principles in the Assessment and Treatment of Late-Life Neuropsychiatric Syndromes
    Physiology and Pathology of Aging / Calvin H. Hirsh and Ana Hategan
    Comprehensive Geriatric Assessment / Calvin H. Hirsh and Tricia K. W. Woo
    Neuroimaging in Clinical Geriatric Psychiatry / Amer M. Burhan, Udunna C. Anazodo and Jean-Paul Soucy
    Neuropsychology in Late Life / Heather E. McNeely and Jelena P. King
    Pharmacotherapy: Safe Prescribing and Adverse Druge Events / Calvin H. Hirsch, Shyam Maharaj and James A. Bourgeois
    Somatic Therapies: Electroconvulsive Therapy / Carole Lazaro, Lisa A. McMurray, Milena Rogan Ducic and Timothy E. Lau
    Somatic Therapies: Repetitive Transcranial Magnetic Stimulation (rTMS) and Deep Brain Stimulation (DBS)
    Psychotherapy in Late Life / Caroline Giroux and W. Edwin Smith
    Ethics, Mental Health Law, and Aging / Daniel L. Ambrosini, Calvin H. Hirsch and Ana Hategan. II: Common Clinical Psychiatric Diagnoses in Late Life
    Late-Life Depression / Tracy Cheng
    Late-Life Bipolar Disorders / Tracy Cheng and Karen Saperson
    Late-Life Anxiety Disorders / Sachin Sarin and Zainab Samaan
    Obsessive-Compulsive and Related Disorders in Older Age / Shannon Suo and Puja Chadha
    Trauma and Stressor-Related Disorders in Late Life / Caroline Giroux and Andrés F. Sciolla
    Late-Life Psychosis / Jessica E. Waserman and Karen Saperson
    Substance Use Disorders in Late Life / Jeffrey DeVido, Calvin H. Hirsch, Nitika Sanger, Tea Rosic, Zainab Samaan and James A. Bourgeois
    Delirium in Older Adults / Ana Hategan, Calvin H. Hirsch, Deborah Francis and James A. Bourgeois
    Major or Mild Neurocognitive Disorder Due to Alzheimer Disease / Ana Hategan and Glen L. Xiong
    Major or Mild Frontotemporl Neurocognitive Disorder / Ana Hategan, James A. Bourgeois and Calvin H. Hirsch
    Major or Mild Neurocognitive Disorders wit Lewy Bodies / Poh Choo How, Pachida Lo and Glen X. Xiong
    Major or Mild Vascular Neurocognitive Disorder / Amer M. Burnham, Manoosh Moradizadeh and Nicole E. Marlatt
    Neuropsychiatric Symptoms of Major or Mild Neurocognitive Disorders / Amer M. Burnham, Calvin H. Hirsch and Nicole E. Marlatt
    Neuropsychiatric Manifestations of Systemic Medical Conditions / Mariam Abdurrahman
    Sleep Wake Disorders in Late Life / Zahida Maghji, Ana Hategan and Akua Amoako-Tuffour
    Personality Disorders in Late Life / Caroline Giroux and W. Edwin Smith III: Special Topics
    Psychosomatic Medicine/Consultation-Liaison Psychiatry in Late Life / James A. Bourgeois and Caroline Giroux
    Aging with Intellectual and Development Diabilities / Kerry Boyd and Veronique Baril
    Psychoatric Emergencies in Older Adults / Timothy E. Lau, Sarah Russell, Elizabeth Kozyra and Sophiya Benjamin
    Geriatric Forensic Psychiatry: Risk Assessment and Management / Joseph C. Ferencz, Gary A. Chaimowitz and Caroline Giroux
    Marginalized Geriatric Patients / Albina Veltman and Tara La Rose
    Sexuality and Sexual Dysfunction in Later Life / Daniel L. Ambrosini, rosemary Chackery and Ana Hategan
    Againg and Mental Health in the Era of Globalization / Mariam Abdurrahman
    Palliative Care for Geriatric Psychiatric Patients with Life-Limiting Illness / Margaret W. Leung, Lawrence E. Kaplan and James A. Bourgeois
    Caregiver Burnout / Kurtis S. Kaminishi, Reza Safavi and Calvin H. Hirsch
    Geriatric Telepsychiatry: Opportunities, Models and Outcomes / Donald M. Hilty, Shilpa Srinivasan amd Terry Rabinowitz.
    Digital Access Springer 2018
  • Digital
    Ana Hategan, James A. Bourgeois, Tracy Cheng, Julie Young.
    Summary: This book features approximately 300 short-answer questions on geriatric psychiatry topics, each comprising the stem of a brief clinical scenario or concise question with expected number of answers. The book also features detailed teaching notes, graphics, and the respective source references. The format is consistently structured from chapter to chapter, practical and concise, and designed to enhance the reader's diagnostic and management ability and clinical understanding. Each answer includes a concise discussion, pertinent illustrations, and source references. This text is a valuable reference and teaching tool that provides an opportunity for learning across a rapidly growing field. The material covered matches the existing postgraduate curricula in geriatric psychiatry and helps prepare candidates for their specialty and subspecialty certification examinations. The cases map well to both the American Geriatric Psychiatry Association and Canadian Academy of Geriatric Psychiatry as well as other international postgraduate curricula. Geriatric Psychiatry Study Guide is the ultimate resource for students, residents, fellows, psychiatrists, psychologists, family practitioners, nurses, social workers, and all clinicians rising to the challenges of the mental health segment of the geriatric workforce.

    Contents:
    Physiology and Pathology of Aging
    Neuropsychology and Neuroimaging in Clinical Geriatric Psychiatry
    Pharmacotherapy, Somatic Therapies, and Psychotherapy in Late Life
    Ethics and Law
    Late-life Depressive Disorders, Bipolar Disorders, and Psychotic Disorders
    Late-life Anxiety Disorders, Obsessive-Compulsive and Related Disorders, and Trauma- and Stressor-Related Disorders
    Substance Use Disorders in Older Adults
    Comorbid Systemic Medical and Psychiatric Illness in Older Adults
    Common Major and Mild Neurocognitive Disorders: Alzheimer Disease, Frontotemporal, Lewy Body, and Vascular Types
    Other Major and Mild Neurocognitive Disorders: Parkinson Disease, Atypical Parkinsonism, and Traumatic Brain Injury Types
    Neuropsychiatric Symptoms due to Major and Mild Neurocognitive Disorders
    Sleep-Wake Disorders in Late Life
    Personality Disorders in Late Life
    Aging with Neurodevelopmental Disorders: Intellectual Disability and Autism Spectrum Disorder
    Emergencies in Geriatric Psychiatry
    Sexuality and Sexual Dysfunctions in Later Life
    Elder Abuse and Neglect
    End-of-Life Care
    Caregiver Burnout
    Physicians as Leaders in Improving Health Care.
    Digital Access Springer 2018
  • Digital
    K. Rao Poduri.
    Contents:
    Section I. Basics of aging
    section II. Geriatric syndromes
    section III. Systemic disorders in geriatric rehabilitation
    section IV. Health maintenance, caregiving, and postacute rehabilitation : bedside to curbside.
    Digital Access TandFonline 2017
  • Digital
    Shilpa Srinivasan, Juliet Glover, James G. Bouknight, editors.
    Digital Access Springer 2017
  • Digital
    Aurelio Rodriguez, Robert D. Barraco, Rao R. Ivatury, editors.
    Summary: The purpose of this book is to give providers of all levels a simple and essential source of practical information in treating the elderly trauma and emergency surgery patient. The Introduction instructs practitioners how to evaluate and assess risk including frailty and use this information in Goals of Care discussions to facilitate shared decision making so crucial to this population. The individual chapters consist of best practices and care guidelines from some of the most well-known thought leaders and best trauma centers in the country across the spectrum from geriatricians to trauma and acute care surgeons and nurses. Each chapter contains easy-to-read algorithms and references that the readers can use and adapt for their own setting. Chapters on Pre-hospital care will help guide EMS organizations and even systems in the right care and triage of the elderly. Each chapter also contains a Nursing Focus section for helpful nursing tips in caring for the eld erly with those injuries and problems. These sections make this book a must-have for any center looking to improve its care of the elderly patient or just trying to be sure its care is already the best it can be. A special section on Post Acute Care will introduce the provider to the common issues surrounding particular disposition destinations for the elderly patient. This will facilitate discussions with families, case managers and facilities to help improve time to disposition.

    Contents:
    Section I: Introduction
    Rationale
    Systems Impact
    Comorbidities
    Goals of Care
    Section II: Trauma
    Introduction
    Trauma
    Prehospital Care
    Head Injury
    Spine Injury
    Orthopedic Injury
    Cardiothoracic Injury
    Abdominal Injury
    Urologic Injury
    Plastics/Skin and Soft Tissue Injury
    Thermal Injury
    Section III: Acute Care Surgery
    Background
    Common Abdominal Emergencies
    Section IV: Post-Acute Care
    Considerations in Disposition.
    Digital Access Springer 2018
  • Digital
    edited by Jay A. Yelon, Fred A. Luchette.
    Summary: Geriatric Trauma and Critical Care provides a multidisciplinary overview of the assessment and management of the elderly patient presenting with surgical pathology. By utilizing current literature and evidence-based resources, the textbook elucidates the unique nature of caring for the elderly population. The structure of the volume provides the reader with an overview of the physiologic and psychological changes, as well as the impact on the healthcare system, associated with the aging process. Emphasis is placed on the impact of aging, pre-existing medical problems, effects of polypharmacy, advanced directives and end-of-life wishes on acute surgical problems, including trauma and surgical critical care. Special attention is given to the ethical implications of management of the aged. The multidisciplinary contributors provide a unique point of view not common to surgical texts. The textbook is the definitive resource for practicing surgeons, emergency medicine physicians, intensivists, anesthesiologists, hospitalists, geriatricians, as well as surgical residents, nurses and therapists, all who care for elderly patients with surgical emergencies.

    Contents:
    SECTION I: IMPACT OF AGING ON HEALTH
    1. Changing Demographics of the American Population
    2. Cardiovascular Physiology
    3. Pulmonary Artery
    4. Renal Function in the Elderly
    5. Skin, Soft Tissue, and Wound Healing in the Elderly
    6. Immunologic
    7. Hematological Changes with Aging
    8. Geriatric Psychology and the Injured Elderly
    9. Health Care Economics and the Impact of Aging on Rising Health Care Costs
    10. Operative Risk Stratification
    SECTION II: SURGICAL EMERGENCIES IN THE ELDERLY
    11. Appendicitis
    12. Biliary
    13. Diverticulitis
    14. Intestinal Obstruction
    15. Intestinal Hemorrhage in the Elderly
    16. Acute Abdomen
    17. Necrotizing Soft Tissue Infections
    18. Acute Vascular Insufficiency in the Elderly
    19. Thoracic Diseases in the Elderly
    SECTION III: TRAUMATIC INJURY IN THE ELDERLY
    20. Epidemiology of Injury in the Elderly
    21. Geriatric Trauma and Injury Prevention
    22. Outcomes for Surgical Care in the Elderly
    23. Geriatric Neurotrauma
    24. Chest Wall Injury
    25. Thoracic
    26. Pelvic Fracture
    27. Extremity Injury
    28. Penetrating Injury in the Elderly
    29. Critical Care Epidemiology and Outcomes/Resource Use in the Elderly
    30. Cardiovascular/Invasive Monitoring
    SECTION IV: CRITICAL CARE MANAGEMENT OF THE ELDERLY PATIENT
    31. Pulmonary Critical Care and Mechanical Ventilation
    32. Renal Replacement Therapy (RRT)
    33. Nutrition Support
    34. Pharmacology
    35. Rehabilitation Concerns in Geriatric Trauma
    36. End-of-Life Care
    37. Ethics in Geriatric Trauma.
    Digital Access Springer 2014
  • Digital
    Tomas Lindor Griebling, editor.
    Summary: Geriatric urology represents one of the largest overall sectors of care provided within the specialty of urology. As the incidence and prevalence of many clinical urologic conditions increase significantly in older adults, the practice of urology involves a need for advanced knowledge of the basic principles of geriatrics. Geriatric Urology outlines important topics in the care of elderly urology patients. The first section covers the biology of aging, changes in the genitourinary system, and common diseases including urologic conditions that may serve as warning signs of other disorders. Section two covers geriatric syndromes and implications for urologic care including frailty, polypharmacy, dementia, , and wound healing. Urologic conditions in older adults are explored in detail including urinary incontinence, pelvic organ prolapse, urinary tract infection, nocturia, and benign prostate diseases. Other topics covered include obtaining informed consent, development of advance directives, palliative medicine and care of the dying patient. Geriatric Urology is of great value to urologists, geriatricians, internists, residents and family practitioners.
    Digital Access Springer 2014
  • Digital
    John R. Burton, Andrew G. Lee, Jane F. Potter, editors.
    Summary: This book focuses on the circumstances that lead to the marked increased vulnerability of seniors and are most challenging to clinicians including the presence of multiple chronic medical conditions, variable losses of physiological function, and heterogeneity among individuals. Written by the experts who lead the initiative to deliver high quality surgical and medical care to the elderly, Geriatrics for Specialists is the first book of its kind to provide the comprehensive knowledge specialists and associated generalists need to deliver quality health care to seniors. With topics on important cross cutting issues like frailty, delirium and polypharmacy and specialty chapters on emergency medicine, anesthesia, many surgical and medical disciplines and rehabilitation, this book provides clinicians the knowledge and tools needed to evaluate, treat and manage the unique needs of seniors. Geriatrics for Specialists was created as a resource for specialist, generalists and allied health professionals and their students and trainees who care for elderly patients.

    Contents:
    Frailty
    Delirium
    Emergency Medicine
    Anesthesiology
    General and Trauma Surgery
    Ophthalmology
    Otolaryngology
    Urology
    Orthopedic Surgery
    Vascular Surgery
    Cardiovascular/Thoracic Surgery
    Gynecology
    Physical Medicine and Rehabilitation
    The Specialties of Internal Medicine
    Cardiology
    Nephrology
    Gastroenterology
    Endocrinology
    Rheumatology
    Pulmonary Medicine.
    Digital Access Springer 2017
  • Digital
    Andrew G. Lee, Jane F. Potter, G. Michael Harper, editors.
    Summary: This book aims to be a single point of reference for advances in the care of geriatric populations across medical and surgical specialties. The aging population is a unique demographic with its own health challenges. Geriatricians are specifically trained to address these challenges but few medical students or residents enter geriatrics, even as the demand for geriatric expertise increases. The practices of many medical and surgical specialists are dominated by older patients who may themselves see many specialists but rarely visit geriatricians. This updated edition elucidates the most common medical conditions seen in aging patients and translates approaches to those conditions for physicians across specialties. Divided into three sections that assemble crosscutting issues, medical specialties, and surgical and related specialties, this book serves as a guide for clinicians of all backgrounds who will work with older patients as the demographic ages further. This second edition of Geriatrics for Specialists expands the number of specialist chapters to reflect growth in research in aging and clinical care for older people in dermatology, plastic surgery, and behavioral neurology. All original chapters from the first edition are extensively revised and updated to reflect the rapid growth of new knowledge in the field.

    Contents:
    Frailty
    Delirium
    Preoperative Evaluation
    Psychiatric Disorders in Older Adults
    Medication Management
    Palliative Care and End-of-Life Issues
    Hospital Medicine
    Screening Tools for Geriatric Assessment by Specialists
    Cardiothoracic Surgery
    Emergency Medicine
    Geriatric Trauma and Emergency General Surgery
    Special Evidence-Based Considerations in Geriatric Gynecologic Care: Pelvic Floor Disorders
    Geriatric Cross-Cutting Issues in Ophthalmology
    Geriatric Orthopaedic Surgery
    Rehabilitation
    Urology
    Vascular Surgery
    Rheumatology
    Cardiovascular Disease
    Endocrinology
    Gastroenterology
    Infection and Immunity in Older Adults
    Kidney Disease
    A Geriatric Perspective on Oncology Care
    Pulmonary and Critical Care Medicine
    Behavioral Neurology
    Geriatric Dermatology.
    Digital Access Springer 2021
  • Digital
    Michael L. Malone, Elizabeth A. Capezuti, Robert M. Palmer, editors.
    Contents:
    Section One: Hospital-based models of care:1. Acute Care for Elders
    2. Hospital Elder Life Program
    3. The ACE Consult program
    4.The Advanced Dementia Consult program
    5. Acute Care for Elders (ACE) Tracker and "e-Geriatrician" telemedicine program
    6. The NICHE program to prepare the workforce to address the needs of older patients
    Section Two: Models to address the needs of seniors in transition from hospital to home: 7. Care Transitions Intervention.-8. The Mary Naylor Advanced Practice Nurse model
    9. Project BOOST
    Section Three: Outpatient-based models of care: 10. The GRACE model. 11. The Guided Care model
    12. The Stanford Chronic Disease Self-Management program
    13. Patient Centered Medical Home
    14. Hospital at Home model
    15. The Physician Home Visit program.-16. Geriatrics Evaluation and Management (GEM) program
    Section Four: Emergency Department models of care: 17. Geriatrics Emergency Department
    the GEDI WISE program
    Section Five: Models which address the needs of vulnerable populations: 18. The Evercare program to care for vulnerable elders in skilled nursing facilities
    19. The UCLA Dementia coordinator program
    20. The Wisconsin Alzheimer's Institute memory assessment program. 21. Memory Care Connections and LEEPS program for early memory assessment
    Section Six: Community related- models of care: 22. Stepping On-falls prevention program
    23. Program of All-Inclusive Care of Elders (PACE model)
    24. Wisconsin Family Care social model to support seniors in their homes.
    Digital Access Springer 2015
  • Digital
    Anastassia Kossioni, editor.
    Summary: This book provides basic knowledge and skills for non-dental healthcare practitioners, helping them recognize the importance of oral health, perform initial oral health assessments, consult dentists when necessary, and offer preventive advice and counseling. As people age, they tend to refrain from routine dental care, while the number of consultations with non-dental healthcare providers (physicians, nurses, pharmacists, physician assistants, physical therapists, occupational therapists etc.) increases. However, few healthcare providers are adequately trained to assess oral problems. The relevance of this book is underscored by the recently published European policy recommendations on oral health in older adults by the European College of Gerodontology and the European Geriatric Medicine Society, which highlight the importance of the active involvement of non-dental primary care practitioners in oral health assessment and promotion. These two respected European Societies have identified a significant gap in education, practice and health policies and described the necessary action plans. This book helps to fill the educational gap identified in the recommendations and will be an invaluable tool for all healthcare providers working with older people.

    Contents:
    Intro
    Foreword
    Preface
    Contents
    1: Introduction to Gerodontology: Demography, Epidemiology, and Access to Dental Care
    1.1 The Demography of Ageing
    1.2 Healthy Life Expectancy and Healthy Ageing
    1.3 Oral Health: An Important Element of Healthy Ageing
    1.4 Barriers and Enablers to Oral Health and Care in Old Age
    1.4.1 Barriers to Oral Health
    1.4.1.1 Personal Barriers
    1.4.1.2 Lack of Professional Support
    Dental Professionals
    Non-dental Healthcare Professionals
    1.4.1.3 Lack of Appropriate Health Policies and Legislations 1.4.2 Enablers to Oral Health Promotion in Older Adults
    1.4.2.1 Gerodontology Education and Research
    Education for Dental Professionals
    Education for Non-dental Healthcare Professionals
    Education for Formal Caregivers
    Interprofessional Education and Collaborative Practice
    Research and Development of Good Practice Guidelines for the Dental Management of Older People
    1.4.2.2 Health Policy Actions
    1.5 Conclusion
    References
    2: The Ageing Mouth
    2.1 Introduction
    2.2 Normal Anatomy and Physiologic Age-Related Changes in the Oro-Facial System
    2.2.1 Teeth 2.2.2 Periodontium and Alveolar Bone
    2.2.3 Oral Mucosa
    2.2.4 Salivary Glands
    2.2.5 Oral Function
    2.3 Common Oral Diseases in the Elderly
    2.3.1 Caries and Pulpitis
    2.3.2 Gingivitis and Periodontitis
    2.3.3 Replacement of Lost Teeth with Dental Prostheses
    2.3.4 Pathologies of the Oral Mucosa
    2.3.5 Xerostomia and Hyposalivation
    2.3.6 Impairment of Oral Food Processing, Dysphagia
    2.3.6.1 Oral Phase
    2.3.6.2 Pharyngeal Phase
    2.3.6.3 Evaluation of Oral Function
    2.4 Conclusion
    References
    3: The Association Between Oral and General Health 3.1 Introduction
    3.2 Association Between Oral Health and Pneumonia
    3.3 Oral Health and Cardiovascular Disorders
    3.4 Oral Health and Diabetes Mellitus (DM)
    3.5 Oral Health and Dementia
    3.6 Oral Health and Nutrition
    3.7 Oral Health and Other Disorders
    3.8 Oral Health and Frailty
    3.9 Conclusion
    References
    4: Medications and Oral Health: Points to Consider in Older People
    4.1 Polypharmacy and Medication-Related Problems in Older People
    4.2 Medication-Related Oral Health Problems
    4.2.1 Dry Mouth
    4.2.2 Mucosal Lesions
    4.2.3 Oral Lichen Planus 4.2.4 Taste Alteration-Dysgeusia
    4.2.5 Angioedema
    4.2.6 Gingival Enlargement
    4.2.7 Altered Haemostasis
    4.2.8 Altered Alveolar Bone
    4.2.9 Medication-Related Osteonecrosis of the Jaw
    4.2.10 Oral Pigmentation
    4.2.11 Points to Consider when Prescribing Medications in Older People
    4.2.12 Approaches to Optimize Medication Use
    4.2.13 Medication Reconciliation and Medication Review
    4.2.14 Criteria to Assess Quality of Prescribing
    4.2.14.1 Explicit Tools
    4.2.14.2 Implicit Tools
    4.2.15 Comprehensive Geriatric Assessment (CGA) and Tailored Care
    4.3 Conclusion
    Digital Access Springer 2020
  • Digital
    José García-Alonso, César Fonseca, editors.
    Summary: This book gathers revised selected papers from the 3rd International Workshop on Gerontechnology, IWoG 2020, held on October 5-6, 2020, in Évora, Portugal. They reports on cutting-edge technologies and optimized workflows for promoting active aging and assisting and elderly people at home, as well as in healthcare centers. It discusses the main challenges in the development, use and delivery of health care services and technologies. Not only they proposes solutions for improving in practice the monitoring and management of health parameters and age-related diseases, yet they also describes improved approaches for helping seniors in their daily tasks and facilitating their communication and integration with assistive technologies, thus improving their quality of life, as well as their social integration. The book provides health professionals, researchers, and service providers with extensive information on the latest trends in the development and practical application of gerontechnology in elderly care.

    Contents:
    Smarts technologies and algorithms for Health
    Detecting and Monitoring Depression Symptoms According to People’s Behaviour Through Mobile Devices
    Time series forecasting to predict the evolution of the functional profile of the elderly persons
    The Role of the Blockchain Technology in the Elderly Care Solutions: a Systematic Mapping Study
    MoRES: A mobile app to help elderly people grasp and comply with COVID-19 restrictions
    Qualitative research in evaluation. An usability evaluation protocol for the Assistant on Care and Health Offline (ACHO)
    Technologies to increase the quality of life of the elderly population
    A self-sustainable DTN solution for isolation monitoring in remote areas
    Training Proposal for the Elderly with Changes in Self Care and for their Caregiver: Rehabilitation Nursing Care Contributions
    PSIQUE: A computerised neuropsychological assessment App
    Indicators sensitive to rehabilitation nursing care: a functional and technological respiratory rehabilitation program for elderly people
    Experiences and definitivions of loneliness. The use of technology for anthropological analyses.
    Digital Access Springer 2021
  • Digital
    [edited by] Sue E. Meiner, Jennifer J. Yeager.
    Summary: This disorder-focused gerontologic nursing text features an enhanced focus on nursing management and care coordination across health care delivery settings. It emphasizes topics such as nutrition, chronic illness, emergency treatment, patient teaching, home care, and end-of-life care -- and includes the latest guidelines for mammograms, colonoscopies, pneumonia, and shingles vaccinations--Publisher.

    Contents:
    Overview of gerontologic nursing / Jennifer J. Yeager
    Theories related to care of the older adult / Jennifer J. Yeager
    Legal and ethical issues / Carol Ann Amann
    Assessment of the older adult / Jennifer J. Yeager
    Cultural influences / Carol Ann Amann
    Family influences / Jennifer J. Yeager
    Socioeconomic and environmental influences / Colleen Steinhauser
    Health promotion and illnesses/disability prevention / Ashley N. Davis
    Nutrition / Neva L. Crogan
    Sleep and activity / Jennifer J. Yeager
    Safety / Debra L. Sanders
    Sexuality and aging / Jennifer J. Yeager
    Pain / Joanne Alderman
    Infection and inflammation / Jennifer J. Yeager
    Laboratory and diagnostic tests / Jennifer J. Yeager
    Drugs and aging / Jennifer J. Yeager
    Integumentary function / Jennifer J. Yeager
    Sensory function / Beth Culross
    Cardiovascular function / Mary B. Winton
    Respiratory function in aging / Debra L. Sanders
    Gastrointestinal function / Jennifer J. Yeager
    Urinary function / Jennifer J. Yeager
    Musculoskeletal function / Laurie Kennedy-Malone
    Cognitive and neurologic function / Jennifer J. Yeager
    Endocrine function / Mary B. Winton
    Health care delivery settings and older adults / Linda Bub
    Chronic illness and rehabilitation / Beth Culross
    Cancer / Jennifer J. Yeager
    Loss and end-of-life issues / Linda Bub
    Appendix A: Values history form
    Appendix B: U.S. advocacy organizations for older adults
    Appendix C: Chronic illness and rehabilitation resources.
    Digital Access ClinicalKey Nursing 2019
  • Digital
    [edited by] Kristen L. Mauk.
    Summary: "Gerontological Nursing takes a holistic, interdisciplinary approach, arming pre-licensure nursing students with the essential competencies required to provide quality patient care for the older adult. As the older adult population grows, gerontological nursing remains a critical specialty area for nursing, and this text prepares students to effectively care for this population. Following the framework laid out by the AACN's Recommended Baccalaureate Competencies and Curricular Guidelines for the Nursing Care of Older Adults, the current edition leads nursing students through the core foundations of gerontological nursing as a specialty and emphasizes essential competencies alongside management of geriatric syndromes - such as falls, sleep disorders and depression/anxiety - and various issues affecting gerontological care, ranging from cultural to spiritual to elder abuse. Research highlights, critical thinking/personal reflection exercises and case studies introduce real-world examples that help students fully grasp the material"-- Provided by publisher.

    Contents:
    Introduction to Gerontological Nursing
    The Aging Population
    Theories of Aging
    Review of the Aging of Physiological Systems
    Therapeutic Communication with Older Adults, Families and Caregivers
    Comprehensive Assessment of the Older Adult
    Promoting Healthy Aging, Independence and Quality of Life
    Identifying and Preventing Common Risk Factors
    Review of the Management of Common Illnesses, Diseases, or Health Conditions
    Nursing Management of Dementia
    Polypharmacy
    Falls in Older Adults
    Delirium
    Anxiety and Depression in the Older Adult
    Urinary Incontinence
    Sleep Disorders
    Dysphagia and Malnutrition
    Pressure Ulcers
    The Interdisciplinary Team
    Culture and Spirituality
    Sexuality
    Elder Abuse and Mistreatment
    Pain Management and Alterative Health Modalities
    Disaster Preparation, Response and Recovery
    End-of-Life Care
    Care Transitions, System Models, and Health Policy in Aging.
    Digital Access R2Library 2023
  • Digital
    Patricia A. Tabloski.
    Summary: "Are you looking into how to advance your professional development through certification? Need a reliable and credible reference resource? No matter where you are in the process, make sure you have the most valuable review and resource tool at your disposal. The Gerontological Nursing Review and Resource Manual, 4th Edition is a must-have tool for nurses planning to take the American Nurses Credentialing Center's (ANCC's) Gerontological Nursing certification exam. Based on the official ANCC certification exam test content outline, this review and resource manual will help you: Study and analyze comprehensive material and concepts written by nursing experts. Develop a recommended seven-step plan to equip you for the exam and map out what to do on the day of the exam. Prepare for and familiarize yourself with gerontological nursing standards of practice. And much more ... Make the Gerontological Nursing Review and Resource Manual a key resource in your certification preparation"-- Provided by publisher

    Contents:
    Preparing for the Certification Examination
    The Older Adult
    Development of Gerontological Nursing Practice
    Theories of Aging
    Gerontological Nursing Issues
    Mental Health
    Medications
    Nutrition
    Health Promotion and Wellness
    Lifestyle, End of Life Care, and Recognizing Vulnerability in the Older Adult
    Chronic Illness and Pain
    Assessment of Laboratory Values
    Cardiovascular Disease
    Respiratory Diseases
    Gastrointestinal Diseases
    Urinary and Reproductive Diseases
    Chronic and End-Stage Kidney Disease, Hematology, Sexually Transmitted Infections, and Immunologic Disorders
    Musculoskeletal Diseases
    Disorders of the Integumentary System
    Sleep Disorders/Sensory Disorders.
    Digital Access R2Library 2020
  • Digital
    Jozef Rovensky, editor.
    Contents:
    Pathogenesis, clinical symptoms and therapy of rheumatoid arthritis
    Osteoporosis in rheumatoid arthritis in elderly patients
    Biological therapy of rheumatoid arthritis
    Systemic lupus erythematosus
    Sjogren's syndrome
    Systemic scleroderma
    Vasculitis
    Polymyalgia rheumatic and giant cell arteritis
    Aortic aneurysm as a cause of death in giant cell arteritis
    Relapsing polychondritis
    RS3PE : a disease or a syndrome?
    Clinical and laboratory features of paraneoplastic rheumatic syndromes
    Osteoarthritis
    Arthropathy in hemochromatosis
    Diabetic Charcot's neurogenic osteoarthropathy
    Changes of musculoskeletal system in metabolic syndrome
    Clinical symptoms in gouty arthritis
    X-ray and ultrasound picture of chondrocalcinosis
    Alkaptonuria and ochronosis
    Metabolic osteopathy in celiac disease manifested in elderly patients
    Celiac disease in elderly patients
    Bone and joint involvement in celiac disease
    Diffuse idiopathic skeletal hyperostosis
    Senile osteoporosis
    Nutrition and osteoporosis
    Neck and shoulder pain
    Vertebrogenic diseases
    Pain
    Pharmacological treatment of rheumatic diseases
    Drug-induced rheumatic syndromes
    Rehabilitation in rheumatic diseases
    Surgical treatment of the consequences of rheumatic diseases
    Paget's disease of bone
    Involutional osteoporosis: sarcopenia, frailty syndrome and falls
    Systemic enzyme therapy in complex treatment of degenerative rheumatic diseases in the elderly patients.
    Digital Access Springer 2017
  • Digital/Print
    Neuburger, Max.
    Digital Access
    Provider
    Version
    Google Books
    Print Access Request
    Location
    Version
    Call Number
    Items
    Stored offsite. Please request print.
    R131 .N479
    2
  • Print
    ... von Dozent Dr. Wilhelm Thomsen ... ; mit einem Geleitwort von Prof. Dr. Georg Hohmann ...
    Contents:
    I. T. Die Ideen Hermann von Meyer's über die Schuhfrage auf Grund seiner Originalschriften.
    Print Access Request
    Location
    Version
    Call Number
    Items
    Stored offsite. Please request print.
    M781 .T41 1940
    1
  • Digital
    volume editors, Annunziata Lapolla, Boyd E. Metzger.
    Summary: "Diabetes mellitus, one of the most important complications of pregnancy, can cause a wide range of problems during pregnancy for women and their developing babies. This book is published with the objective of providing a comprehensive overview of the clinical characteristics/features of types 1 and 2 diabetes in pregnancy as well as gestational diabetes mellitus (GDM). To reach this aim, the focus is on up-to-date information on physiopathology, diagnosis, autoimmunity, genetic, omics, management, and treatment"-- Provided by publisher.
    Digital Access Karger 2020
  • Digital
    Bhagyalaxm Nayak, Uma Singh, editors.
    Summary: This book covers the entire spectrum of gestational trophoblastic disease from the most benign to the most malignant form. It addresses etiopathogenesis, molecular basis of the disease, risk assessment, management and follow-up. Management in the form of surgical, medical and supportive care is discussed in detail to help the practitioner in making treatment decisions. Special and rare varieties of the disease are dealt separately. A separate section in each chapter covers critical conditions arising from the disease. Case based discussions make the chapters more lively and interesting. The recent trials and studies are also covered in the book. Topics such as fertility preservation, gestational trophoblastic diseases registry and development of voluntary organizations for supporting patients are value additions to this book. This book is meant for the general obstetrician and gynecologist and for the gynecologic oncologist as well.

    Contents:
    Introduction or overview of Gestational Trophoblastic Disease
    Epidemiology of Gestational Trophoblastic Disease
    Genetics and Pathogenesis : A recent update
    Human chorionic Gonadotropin
    Molecular markers in Gestational Trophoblastic Disease
    Imaging in Gestational Trophoblastic Disease and Implication of uterine artery Doppler study
    Hydatidiform mole with coexisting with live foetus : management guidelines
    Management of low risk Gestational Trophoblastic Neoplasia
    High risk Gestational Trophoblastic Neoplasia
    Ultrahigh-risk Gestational Trophoblastic Neoplasia
    The dynamic scoring system and staging
    Surgical mnagement of Gestational Trophoblastic Disease
    Placental site and epithelioid trophoblastic tomours: rare varieties of Gestational Trophoblastic Neoplasia
    Critical conditions in Gestational Trophoblastic Diseases
    Recurrent Molar Pregnancy
    Fertility preservation in Gestational Trophoblastic Neoplasia (GTN)
    Follow up Gestational Trophoblastic Disease: how often and how long?
    Establishment of regional centers for Gestational Trophoblastic Disease follow up and Referral and Gestational Trophoblastic Disease registry.
    Digital Access Springer 2021
  • Digital/Print
    Digital Access Google Books 1894-
    Print Access Request
    Location
    Version
    Call Number
    Items
    Stored offsite. Please request print.
    I776 .G37 1899
    1
  • Digital
    Michael Sabel.
    Contents:
    Planning a procedure : the importance of visualization
    The craniotomy
    Working with the microscope
    Removing a gyrus : the principle of subpial resection
    Removing an artificial brain tumor
    Microsurgical training : the chicken wing model.
  • Digital
    Margaret L. Andersen.
    Summary: "The purpose of this book is to provide an accessible introduction to understanding racial inequality-and to do so with the hope that a more informed understanding will help readers know what to do about it"-- Provided by publisher.

    Contents:
    Introduction
    Race
    Feeling race in everyday life
    Who, me?
    What did you say?
    But that was then-I didn't have anything to do with it
    Getting smart about race, then doing something about it
    Appendix A Finding common ground: questions for conversation
    Appendix B Further resources
    Notes
    Index
    About the author.
    Digital Access 2020
  • Digital
    Arthur L. Caplan, Barbara K. Redman, editors.
    Summary: This book represents the first comprehensive, gold standard reader on research integrity in the biomedical sciences. Now more than ever, the responsible conduct of research (RCR) has become critically important as new technologies affect research practices in both positive and negative ways. Since learning to do science and practicing it brings researchers into contact with a vast array of ethical issues, it is critical to know the standards and how they are evolving. Indeed, research integrity requires scientists at all levels to operate ethically in a system that supports ethical practice. This unique, foundational text covers all the relevant areas -- subject protection, research misconduct and conflict of interest as well as newly quantified concerns about research bias and non-reproducibility, as well as other unique issues. Developed by renowned experts, this compelling title discusses the full range of practices and policies that should support research that is honestly produced and disseminated. It also specifically incorporates topics noted by the National Institutes of Health as essential and required for training in RCR. Getting to Good - Research Integrity in the Biomedical Sciences is a major contribution to the literature on bioethics and will serve as an invaluable resource for all researchers, students, administrators and professionals interested in research ethics and integrity.

    Contents:
    Chapter 1. Methodology
    Chapter 2. Policy
    Chapter 3. Reproducibility
    Chapter 4. Human Subjects Proction
    Chapter 5. Responsible Authorship
    Chapter 6. Mentor-Mentee Responsibilities and Relationships
    Chapter 7. Plagarism
    Chapter 8. Peer Review
    Chapter 9. Research Misconduct
    Chapter 10. Whistleblowing
    Chapter 11. Confict of Interest
    Chapter 12. Date Acquisition, Management and Transparency
    Chapter 13. International Research Involving Resource-Constrained Countries
    Appendix.
    Digital Access Springer 2018
  • Digital
    Louis M. Wong kee Song, Emmanuel C. Gorospe, Todd H. Baron, editors.
    Contents:
    Triage Sedation and Monitoring
    Peri-procedural Management of Antithrombotic Agents
    Suspected Non-variceal Upper Gastrointestinal Bleeding
    Approach to Suspected Acute Variceal Bleeding
    Suspected Small Intestinal Hemorrhage
    Suspected Lower Gastrointestinal Bleeding
    Approach to Foreign Body Ingestion, Food Impaction and Caustic Injury
    Non-endoscopic Management of Acute Mechanical Colonic Obstruction and Pseudo-obstruction
    Approach to Acute Cholangitis
    Approach to Endoscopic Adverse Events
    Endoscopic Hemostasis of Acute Non-Variceal Upper Gastrointestinal Bleeding
    Hemostasis of Acute Esophageal Variceal Bleeding
    Hemostasis of Acute Gastric Variceal Bleeding
    Hemostasis of Acute Small Intestinal Bleeding
    Hemostasis of Acute Lower GI Bleeding
    Endoscopic Management of Food Impaction and Foreign Bodies
    Endoscopic Management of Acute Colonic Obstruction and Pseudo-obstruction
    Endoscopic Management of Pancreaticobiliary Emergencies
    Endoscopic Management of Procedure-related Bleeding and Perforation.
    Digital Access Springer 2016
  • Digital
    [edited by] Peter R. McNally.
    Contents:
    Swallowing disorders and dysphagia
    Gastroesophageal reflux disease
    Esophageal causes of chest pain
    Achalasia
    Esophageal cancer
    Esophageal anomalies, infections, and nonacid injuries
    Barrett's esophagus
    Esophageal and stomach pathology
    Gastritis, peptic ulcer disease, NSAIDs, and Helicobacter pylori infection
    Gastric cancer
    Thickened gastric folds
    Gastroparesis
    Evaluation of abnormal liver tests
    General concepts on viral hepatitis
    Antiviral therapy for hepatitis C
    Antiviral therapy for hepatitis B
    Autoimmune hepatitis : diagnosis
    Autoimmune hepatitis : treatment
    Primary biliary cirrhosis and primary sclerosing cholangitis
    Vaccinations and immunoprophylaxis in gastrointestinal and liver disorders
    Pregnancy and liver disease
    Rheumatologic manifestations of hepatobiliary diseases
    Evaluation of focal liver masses
    Drug-induced liver disease
    Alcoholic liver disease, alcoholism, and alcohol withdrawal syndrome
    Vascular liver disease
    Nonalcoholic fatty liver disease and nonalcoholic steatohepatitis
    Liver transplantation
    Ascites
    Liver abscess
    Inheritable forms of liver disease
    Liver histopathology
    Hepatobiliary cystic disease
    Gallbladder disease : stones, crystals, and sludge
    ERCP plus sphincter of Oddi dysfunction
    Acute pancreatitis
    Chronic pancreatitis
    Pancreatic cancer
    Cystic lesions of the pancreas
    Celiac disease
    Crohn's disease
    Ulcerative colitis
    Eosinophilic gastrointestinal disease and eosinophilic esophagitis
    Small intestinal bacterial overgrowth
    Colon disorders and colon cancer
    Constipation and fecal incontinence
    Diverticulitis
    Diseases of the appendix
    Colitis : pseudomembranous, microscopic, and radiation
    Upper gastrointestinal hemorrhage
    Lower gastrointestinal tract bleeding
    Occult and obscure gastrointestinal bleeding
    Evaluation of acute abdominal pain
    Evaluation of acute infectious diarrhea
    Chronic diarrhea
    Aids and the gastrointestinal tract
    Ischemic bowel disease
    Nutrition, malnutrition, and probiotics
    Small bowel and colon pathology
    Foreign bodies and the gastrointestinal tract
    Functional gastrointestinal disorders and irritable bowel
    Endoscopic cancer screening and surveillance
    Rheumatologic manifestations of gastrointestinal diseases
    Dermatologic manifestations of gastrointestinal disease
    Endocrine aspects of gastrointestinal system
    Plain film, barium, and virtual radiography
    Interventional radiology I : cross-sectional imaging procedures
    Interventional radiology II : fluoroscopic and angiographic procedures
    Noninvasive GI imaging : ultrasound, computed tomography, and magnetic resonance imaging
    Nuclear imaging
    Endoscopic ultrasound
    Advanced therapeutic endoscopy
    Esophageal surgery
    Surgery for peptic ulcer disease
    Surgical approach to the acute abdomen
    Colorectal surgery : polyposis syndromes and inflammatory bowel disease
    Obesity and surgical weight loss
    Minimally invasive surgery
    Clinical vignettes.
    Digital Access ClinicalKey 2015
  • Digital
    T.K. Chattopadhyay, editor-in-chief ; Peush Sahni, Sujoy Pal, editors.
    Summary: The 24th volume of this highly successful series includes new contemporary topics such as corrosive injuries of the oesophagus, post-gastrectomy complications, advances in imaging of inflammatory bowel disease, unusual presentations of gallstones, gall bladder cancer with jaundice, minimally invasive pancreatic surgery, and enhanced recovery after surgery. Finally, the chapter on advances in GI surgery, like in each past volume, reviews important new developments in the field. The GI Surgery Annual 24th Volume provides an overall roundup of selected topics that were deemed particularly relevant and topical by the series editors.
    Digital Access Springer 2018
  • Digital
    T.K. Chattopadhyay, editor-in-chief ; Peush Sahni, Sujoy Pal, editors.
    Digital Access Springer 2019
  • Digital
    Peush Sahni, Sujoy Pal, editors ; Editor-in-Chief T. K. Chattopadhyay.
    Summary: The twenty-sixth volume of GI Surgery Annual includes chapters on current and upcoming topics in gastrointestinal surgery pertaining to cholangiopancreatoscopy, robotic liver resections and transplants, primary familial intrahepatic cholestasis, managing a patient after total pancreatectomy, transplant immunology and immunosuppression as well as the chapter on advances in gastrointestinal surgery. The authors have expertise and excellent academic track record in the relevant subspecialties. Marrying academic excellence with publishing expertise is going to be the new mantra for the present as well as the upcoming issues of GI Surgery Annual. .

    Contents:
    1 Total Pancreatectomy and Islet Auto-Transplantation for Chronic Painful Pancreatitis
    2 Cholangiopancreaticoscopy: A distinct diagnostic and therapeutic tool in the current era
    3 Non Cirrhotic Portal Fibrosis
    4 Recent advances in Benign anorectal disorders
    5 Progressive familial intrahepatic cholestasis
    6 Training and Credentialing in Multi-organ retrieval: Indian perspective
    7 Robotic Surgery in Living Donor Liver Transplantation.-8 Assessing of Tumour Response to Neoadjuvant Therapy for the Treatment of Oesophageal Cancer
    9 PROTON BEAM THERAPY IN GASTROINTESTINAL CANCERS: A paradigm shift in radiotherapy
    10 IMMUNOSUPPRESSION IN LIVER TRANSPLANTATION
    11 Advances in Gastrointestinal Surgery.
    Digital Access Springer 2022
  • Digital
    Naci Kocer.
    Summary: This atlas focuses on the imaging and treatment options available for giant intracranial aneurysms since 1990s in the beginning of the so-called modern endovascular era. During this period, there were significant advances made in the therapy of small intracranial aneurysms though the treatment of giant aneurysms continued to pose an insurmountable challenge. At the turn of this century, this grim scenario gradually improved with better understanding of the pathophysiology of giant intracranial aneurysms. This changed scenario in giant intracranial aneurysm therapy has been illustrated with the aid of informative clinical case studies. The clinical presentation of giant aneurysms in adults and children is described as are the merits of different imaging modalities explained and illustrated. Extensive consideration has been given to modern fusion imaging that has improved our insight into the nature of the disease. Endovascular treatment approaches (including illustrative open surgical approaches) and reconstructive and deconstructive strategies are fully documented, with careful attention given to factors that influence management strategies, treatment choice and complications.The atlas will be a valuable reference and practical aid for neuroradiologists, neurosurgeons, neurologists, fellowship trainees, postgraduate & graduate students.
    Digital Access Springer 2016
  • Digital
    Adrian Kasaj editor.
    Summary: This book is designed to serve as a clear and concise clinical manual that covers all aspects of the current management of gingival recession, with a particular focus on surgical techniques with the adjunctive use of autogenous tissues or soft tissue substitutes for recession coverage. A structured overview of the various surgical techniques is provided with the aid of high-quality illustrations, delivering an evidence-based clinical treatment guideline. In addition, individual chapters are dedicated to the classification of gingival recession, etiology and prevalence, clinical examination and diagnosis, decision making, potential complications, and postsurgical care. Gingival recession is a common condition in the adult population and is related to several undesirable conditions such as unaesthetic appearance, root caries, and hypersensitivity. Periodontal plastic surgery is now an important tool in the armamentarium of the clinician treating gingival recessions, and practitioners at all levels will find this book to be an invaluable source of guidance.

    Contents:
    Intro; Contents;
    1: Definition of Gingival Recession and Anatomical Considerations; 1.1 Introduction; 1.1.1 Definition of Gingival Recession; 1.1.2 Clinical Features of Healthy Human Gingiva; 1.1.2.1 Free Gingiva; 1.1.2.2 Attached Gingiva; 1.1.2.3 Interdental Gingiva; 1.1.3 Periodontal Biotype; 1.1.4 Microstructural Anatomy; 1.1.4.1 Oral Epithelium; 1.1.4.2 Sulcular Epithelium; 1.1.4.3 Junctional Epithelium; 1.1.4.4 Gingival Connective Tissue; 1.1.5 How Much Gingival Tissue Do We Need?; References;
    2: Classification of Gingival Recession; 2.1 Introduction; 2.2 Classifications of Gingival Recession; References;
    3: Etiology and Prevalence of Gingival Recession; 3.1 Introduction; 3.2 Predisposing Factors for Gingival Recession; 3.2.1 Bone Dehiscence/Fenestration Defects; 3.2.2 Dimensions of Gingiva; 3.2.3 Aberrant Frenal Attachment; 3.3 Precipitating Factors for Gingival Recession; 3.3.1 Toothbrushing Trauma; 3.3.2 Oral Piercings; 3.3.3 Subgingival Restorations/Partial Dentures; 3.3.4 Deep Traumatic Overbite; 3.3.5 Self-Inflicted Injuries; 3.3.6 Orthodontic Therapy; 3.3.7 Plaque-Induced Periodontal Inflammation; 3.3.8 Herpes Simplex Virus (HSV) Infection; 3.3.9 Smoking; 3.4 Prevalence of Gingival Recession; References;
    4: Gingival Recession: Clinical Examination and Diagnostics; 4.1 Chief Complaint, Specific Reason for the Visit or Referral; 4.1.1 Medical History; 4.1.2 Dental History; 4.2 Clinical Examination; 4.2.1 Aesthetic Assessment; 4.2.2 Mucosa; 4.2.3 Gingiva; 4.2.4 Periodontal Assessment; 4.2.5 Teeth; 4.2.6 Restorations/Appliances; 4.3 Radiographic Assessment; 4.3.1 Periapical Radiograph; 4.3.2 Bitewing Radiograph; 4.3.3 Panoramic Radiograph; 4.3.4 Cone Beam Computed Tomography; 4.4 Data Collection and Documentation; References;
    5: Nonsurgical Management of Gingival Recession and Associated Tooth Hypersensitivity; 5.1 Introduction; 5.1.1 Prevalence and Etiology; 5.1.1.1 Aggressive Toothbrushing; 5.1.1.2 Toothpaste: Relative Dentin Abrasivity; 5.1.1.3 Plaque Control; 5.1.1.4 Periodontal Disease; 5.1.1.5 Facial and Oral Piercings; 5.1.1.6 Orthodontic Treatment; 5.1.2 Toothpastes/Dentifrice; 5.1.2.1 Potassium Nitrate; 5.1.2.2 Strontium; 5.1.2.3 Arginine and Calcium Carbonate; 5.1.2.4 Calcium Sodium Phosphosilicate; 5.1.2.5 High Fluoride Concentration; 5.1.2.6 Fluoride; 5.1.2.7 Hydroxyethyl Methacrylate and Glutaraldehyde; 5.1.2.8 Oxalate; 5.1.2.9 Root Canal Treatment; 5.1.2.10 Surgery; 5.1.2.11 Laser; References;
    6: Basic Principles of Periodontal Plastic Surgery; 6.1 Introduction; 6.2 Primary Intention Healing; 6.2.1 Systemic Factors; 6.2.2 Blood Supply of the Wound; 6.2.3 Flap Preparation; 6.2.4 Flap Mobilization; 6.2.5 Measures to Reduce Tissue Trauma; 6.2.5.1 Magnification Methods; 6.2.5.2 Microsurgical Instruments; 6.2.5.3 Suture Material; 6.3 Wound Stability.
    Digital Access Springer 2018

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