Lane Medical Library

Pt. 1. Pharmacological-based models of addiction -- pt. 2. Neurocomputational models of addiction -- pt. 3. Economic-based models of addiction.

Empirical pharmacokinetics -- Numerical methods for PK parameter estimation -- Physiological aspects on pharmacokinetics -- Modelling the distribution process -- PK/PD modelling.

Part 1. Network components -- 1. Identification of cis-regulatory elements in gene co-expression networks using A-GLAM / Leonardo Mariño-Ramírez ... [et al.] -- 2. Structure-based Ab initio prediction of transcription factor-binding sites / L. Angela Liu and Joel S. Bader -- 3. Inferring protein-protein interactions from multiple protein domain combinations / Simon P. Kanaan ... [et al.] -- 4. Prediction of protein-protein interactions: a study of the co-evolution model / Itai Sharon, Jason V. Davis, and Golan Yona -- 5. Computational reconstruction of protein-protein interaction networks: algorithms and issues / Eric Franzosa, Bolan Linghu, and Yu Xia -- 6. Prediction and integration of regulatory and protein-protein interactions / Duangdao Wichadakul, Jason McDermott, and Ram Samudrala -- 7. Detecting hierarchical modularity in biological networks / Erzsebet Ravasz -- Part 2. Network inference -- 8. Methods to reconstruct and compare transcriptional regulatory networks / M. Madan Babu, Benjamin Lang, and L. Aravind -- 9. Learning global models of transcriptional regulatory networks from data / Aviv Madar and Richard Bonneau -- 10. Inferring molecular interactions pathways from eQTL data / Imran Rashid, Jason McDermott, and Ram Samudrala -- 11. Methods for the inference of biological pathways and networks / Roger E. Bumgarner and Ka Yee Yeung --Part 3. Network dynamics -- 12. Exploring pathways from gene co-expression to network dynamics / Huai Li, Yu Sun, and Ming Zhan -- 13. Network dynamics / Herbert M. Sauro -- 14. Kinetic modeling of biological systems / Haluk Resat, Linda Petzold, and Michel F. Pettigrew -- 15. Guidance for data collection and computational modelling of regulatory networks / Adam Christopher Palmer, and Keith Edward Shearwin -- Part 4. Function and evolutionary systems biology -- 16. Maximum likelihood method for reconstruction of the evolution of eukaryotic gene structure / Liran Carmel, ... [et al.] -- 17. Enzyme function prediction with interpretable models / Umar Syed and Golan Yona -- 18. Using evolutionary information to find specificity-determining and co-evolving residues / Grigory Kolesov and Leonid A. Mirny -- 19. Connecting protein interaction data, mutations, and disease using bioinformatics / Jake Y. Chen, Eunseog Youn, and Sean D. Mooney -- 20. Effects of functional bias on supervised learning of a gene network model / Insuk Lee and Edward M. Marcotte -- Part 5. Computational infrastructure for systems biology -- 21. Comparing algorithms for clustering of expression data: how to assess gene clusters / Golan Yona, William Dirks, and Shafquat Rahman -- 22. Bioverse API and web application / Michal Guerquin ... [et al.] -- 23. Computational representation of biological systems / Zach Frazier ... [et al.] -- 24. Biological network inference and analysis using SEBINI and CABIN / Ronald Taylor and Mudita Singhal.

Introducing computational systems biology / Andres Kriete and Roland Eils -- Enabling information and integration technologies for systems biology. Databases for systems biology / Jürgen Eils ... [et al.] -- Natural language processing and ontology-enhanced biomedical literature mining for systems biology / Xiaohua Hu -- Integrated imaging informatics / Barham Parvin ... [et al.] -- Simpathica : a computational systems biology tool within the valis bioinformatics environment / Bud mishra ... [et al.] -- Standards, platforms, and applications / Herbert M. Sauro -- Foundations of biochemical network analysis and modeling. Introduction to computational models of biochemical reaction networks / F.J. Bruggeman ... [et al.] -- Biological foundations of signal transduction and the systems biology perspective / Ursula Klingmüller -- Reconstruction of metabolic network from genome information and its structural and functional analysis / Hong-Wu Ma and An-Ping Zeng -- Integrated regulatory and metabolic models / Markus W. Covert -- Computer simulations of dynamic networks. A discrete approach to network modeling / Reinhard Laubenbacher and Pedro Mendes -- Gene networks : estimation, modeling and simulation / Seiya Imoto, Hiroshi Matsuno, and Satoru Miyano -- Computational models for circadian rhythms : deterministic versus stochastic approaches / Jean-Christophe Leloup, Didier Gonze, and Albert Goldbeter -- Multi-scale representations of cells and emerging phenotypes. Multistability and multicellularity : cell fates as high-dimensional attractors of gene regulatory networks / Sui Huang -- Spatio-temporal systems biology / Avijit ghosh ... [et al.] -- Cytomics--from cell states to predictive medicine / Günter Valet ... [et al.] -- The IUPS Physiome Project : progress and plans / Peter Hunter ... [et al.].

Functional Genomics and Molecular Networks Gene Expression Regulations in Complex Diseases: Down Syndrome as a Case Study /Marie-Claude Potier and Isabelle Rivals --Reconstructing Models from Proteomics Data /Lysimachos Zografos, Andrew J. Pocklington and J. Douglas Armstrong --Using Chemical Kinetics to Model Neuronal Signalling Pathways /Lukas Endler, Melanie I. Stefan, Stuart J. Edelstein and Nicolas Le Novère --Breakdown of Mass-Action Laws in Biochemical Computation /Fidel Santamaria, Gabriela Antunes and Erik De Schutter --Spatial Organization and Diffusion in Neuronal Signaling /Sherry-Ann Brown, Raquell M. Holmes and Leslie M. Loew --The Performance (and Limits) of Simple Neuron Models: Generalizations of the Leaky Integrate-and-Fire Model /Richard Naud and Wulfram Gerstner --Multi-compartmental Models of Neurons /Upinder S. Bhalla --Noise in Neurons and Other Constraints /A. Aldo Faisal --Methodological Issues in Modelling at Multiple Levels of Description /Kevin Gurney and Mark Humphries --Virtues, Pitfalls, and Methodology of Neuronal Network Modeling and Simulations on Supercomputers /Anders Lansner and Markus Diesmann --Co-operative Populations of Neurons: Mean Field Models of Mesoscopic Brain Activity /David T. J. Liley, Brett L. Foster and Ingo Bojak --Cellular Spacing: Analysis and Modelling of Retinal Mosaics /Stephen J. Eglen --Measuring and Modeling Morphology: How Dendrites Take Shape /Todd A. Gillette and Giorgio A. Ascoli --Axonal Growth and Targeting /Duncan Mortimer, Hugh D. Simpson and Geoffrey J. Goodhill --Encoding Neuronal Models in SBML /Sarah M. Keating and Nicolas Le Novère --NeuroML /Padraig Gleeson, Volker Steuber, R. Angus Silver and Sharon Crook --XPPAUT /Bard Ermentrout --NEST by Example: An Introduction to the Neural Simulation Tool NEST /Marc-Oliver Gewaltig, Abigail Morrison and Hans Ekkehard Plesser.

Basic principles of computed tomography physics and technical considerations / Kyongtae T. Bae and Bruce R. Whiting -- Magnetic resonance imaging principles and applications / Mark A. Brown and Richard C. Semelka -- Interventional computed tomography / Charles T. Burke, Matthew A. Mauro, and Paul L. Molina -- Neck / Franz J. Wippold II -- Thorax: techniques and normal anatomy / Fernando R. Gutierrez, Santiago Rossi, and Sanjeev Bhalla -- Mediastinum / Alvaro Huete-Garin and Stuart S. Sagel -- Lung / Stuart S. Sagel -- Pleura, chest wall, and diaphragm / David S. Gierada and Richard M. Slone -- Heart and pericardium / Pamela K. Woodard ... [et al.] -- Normal abdominal and pelvic anatomy / Dennis M. Balfe, Brett Gratz, and Christine Peterson -- Gastrointestinal tract / Cheri L. Canon -- Liver / Jay P. Heiken, Christine O. Menias, and Khaled Elsayes -- The biliary tract / Franklin N. Tessler and Mark E. Lockhart -- Spleen / David M. Warshauer -- The pancreas / Desiree E. Morgan and Robert J. Stanley -- Abdominal wall and peritoneal cavity / Jay P. Heiken, Christine O. Menias, and Khaled Elsayes -- Retroperitoneum / David M. Warshauer, Joseph K. T. Lee, and Harish Patel -- The kidney and ureter / Mark E. Lockhart, J. Kevin Smith, and Philip J. Kenney -- The adrenal glands / Suzan M Goldman and Philip J. Kenney -- Pelvis / Julia R. Fielding -- Computed tomography of thoracoabdominal trauma / Paul L. Molina ... [et al.] -- Musculoskeletal system / Robert Lopez-Ben, Daniel S. Moore, and D. Dean Thornton -- The spine / Zoran Rumboldt, Mauricio Castillo, and J. Keith Smith -- Pediatric applications / Marilyn J. Siegel.

Heart -- Aorta, arch vessels, and great veins -- Pulmonary arterial disease -- Mediastinum -- Airways -- Focal lung disease -- Lung cancer -- Diffuse lung disease -- Pleura, chest wall, and diaphragm.

Scheduling and preparing for the exam -- Conquering the CCS -- Managing time -- CCS versus reality -- Scoring -- Sample cases.

[Publisher-supplied data] Is our society color-blind? Trans-racial? Post-racial? And what if anything should this mean to professionals in clinical practice with diverse clients? The ambitious volume The Concept of Race and Psychotherapy probes these questions, compelling readers to look differently at their clients (and themselves), and offering a practical framework for more effective therapy. By tracing the racial folk taxonomies of eight cultures in the Americas and the Caribbean, the author elegantly defines race as a fluid construct, dependent on local social, political, and historical context for meaning but meaningless in the face of science. This innovative perspective informs the rest of the book, which addresses commonly held assumptions about problem behavior and the desire to change, and presents a social-science-based therapy model, applicable to a wide range of current approaches, that emphasizes both cultural patterns and client uniqueness. Among the highlights of the coverage: Common elements in therapy and healing across cultures.The psychological appeal of racial concepts despite scientific evidence to the contrary.Lessons psychology can learn from anthropology.Three types of therapeutic relationships, with strategies for working effectively in each.The phenomenon of discontinuous change in brief therapy.Solution-focused therapy from a cross-cultural perspective. Thought-provoking reading for psychologists, psychiatrists, clinical social workers, and other mental health professionals as well as graduate students in these fields, The Concept of Race and Psychotherapy affirms the individuality and the interconnectedness of every client.

The fundamentals : human rights and health -- Humanitarian medicine -- International, UN and WHO cooperation -- Disasters and conflicts -- Science, research and perspectives -- Society, health and equity.

Fundamentals of endotoxin structure and function / Bishop, R.E -- Bacterial exotoxins / Popoff, M.R -- Capsular polysaccharides and their role in virulence / Taylor, C.M., Roberts, I.S -- Fimbriae, pili, flagella and bacterial virulence / Jonson, A.-B., Normark, S., Rhen, M -- Gram-positive adhesins / Talay, S.R -- Microbial pathogenesis and biofilm development / Reisner, A. ... [et al.] -- Bacterial peptidases / Potempa, J., Pile, R.N -- Bacterial invasins : molecular systems dedicated to the invasion of host tissues / Cambronne, E.D., Schneewind, O -- Bacterial iron transport related to virulence / Braun, V -- Pathogenicity islands and their role in bacterial virulence and surviva / Hochhut, B., Dobrindt, U., Hacker, J. -- Horizontal and vertical gene transfer: the life history of pathogens / Lawrence, J.G.

Pharmacogenomics : past, present, and future / Martin M. Zdanowicz -- The genetic basis of pharmacogenomics / Taimour Y. Langaee, Jaekyu Shin -- Methodologies in pharmacogenomics / Christiana L. Aquilante -- The pharmacogenetics of drug metabolism / G. Scott Weston -- Pharmacogenomics and drug transport/efflux / Arthur G. Cox -- Pharmacodynamics and pharmacogenomics / Kathy D. Webster -- Cardiovascular disease / Kathryn M. Momary, Michael A. Crouch -- Hematology/oncology pharmacogenomics / Todd A. Thompson -- Central nervous system / Megan Jo Ehret --Infectious diseases / Tawanda Gumbo, John D. Cleary -- Respiratory diseases / Emily Weidman-Evans, W. Greg Leader -- Toxicogenomics / Helen E. Smith -- The role of pharmacists in pharmacogenomics / Ajoy Koomer, Miriam A. Ansong -- Pharmacogenomics and clinical testing / James W. Fetterman, Jr., Pamela F. Hite -- Pharmacogenomics in pharmacy education / Ajoy Koomer -- Ethical considerations in pharmacogenomics / Sally A. Huston -- Future promise of pharmacogenomics in clinical practice / Jeffery D. Evans.

ch. 1. Introduction to catalysis -- ch. 2. Kinetics -- ch. 3. Reaction rate theory -- ch. 4. Catalyst characterization -- ch. 5. Solid catalysts -- ch. 6. Surface reactivity -- ch. 7. Kinetics of reactions on surfaces -- ch. 8. Heterogeneous catalysis in practice: hydrogen -- ch. 9. Oil refining and petrochemistry -- ch. 10. Environmental catalysis.

Physical examination of the cardiovascular system / Clarke G. Daniels, David V. Daniels, and Kamalendu Chatterjee -- Stress testing / Ian Brown and Donald Schreiber -- Chest pain and the acute coronary syndromes / David V. Daniels, Todd J. Brinton, and David P. Lee -- Cardiogenic shock / David V. Daniels, Todd J. Brinton, and Randall Vagelos -- Bradyarrhythmias and pacing / James V. Freeman and Paul J. Wang -- Wide and narrow complex tachyarrhythmias / David V. Daniels and Amin Al-Ahmad -- Sudden cardiac death and ICD therapy / David V. Daniels and Henry Hsia -- Atrial fibrillation / Anurag Gupta and Paul J. Wang -- Heart failure / David Kao, David V. Daniels, and Euan Ashley -- Pulmonary hypertension / François Haddad ... [et al.] -- Transplant medicine / Michael Pham -- Valvular diseases / Shriram Nallamshetty and Stanley G. Rockson -- Endocarditis / Todd L. Kiefer, Fred A. Lopez, and Randall Vagelos -- Pericardial disease / Todd L. Keifer and Randall Vagelos.

Ethics : principles and professionalism -- Clinical decision-making and ethic skills -- The psychotherapeutic relationship -- Informed consent and decisional capacity -- Ethical use of power in high-risk situations -- Confidentiality and truth telling -- Caring for children -- Caring for people with addictions -- Caring for "difficult" patients -- Caring for people in small communities -- Caring for people at end of life -- Ethical issues in psychiatric genetics -- Ethical issues in managed and evolving systems of care -- Ethical issues in clinician health -- Ethical issues in clinical training -- Ethical issues in psychiatric research -- Health care ethics committees.

Basic Considerations -- Genitourinary System -- Digestive and Hepatobiliary System -- Endocrine System -- Soft Tissue Infection and Inflammation -- Respiratory System -- Skeletal System -- Cardiovascular System -- Central Nervous System -- Nuclear Oncology -- Therapeutic Applications of Nuclear Medicine.

General principles and philosophy -- Resources and strategy -- Common terms -- Combining multiple impairments -- General guidelines for impairment ratings -- Upper extremity -- Lower extremity -- Spine and pelvis -- Skin -- Complex regional pain syndrome, causalgia, reflex sympathetic dystrophy.

"Continuing the tradition of the bestselling first edition, this second edition provides comprehensive coverage of neurobehavioral disorders in children and adults following impact and acceleration accidents. Completely revised and updated, the book includes comprehensive coverage of consciousness including normal, acute, and persistent alterations. Drawing on his training, education, and experience in human physiology, neuroanatomy, and endocrinology, the author not only gives readers a solid foundation for understanding, diagnosing, and treating concussive brain trauma, but also gives them tools to increase standards of care"--Provided by publisher.

Conditional somatic mutagenesis in the mouse using site-specific recombinases -- Cre/loxP-mediated chromosome engineering of the mouse genome -- Tetracycline-controlled genetic switches -- Novel gene switches -- Improved embryonic stem cell technologies -- Gene trap mutagenesis -- RNA interference in mice -- Viral vectors: a wide range of choices and high levels of service -- Conditional mutagenesis by cell-permeable proteins: potential, limitations and prospects -- Analysis of mouse development with conditional mutagenesis -- Conditional mouse models of cancer -- Conditional mutagenesis reveals immunological functions of widely expressed genes: activation thresholds, homeostatic mechanisms and disease models -- Conditional transgenesis and recombination to study the molecular mechanisms of brain plasticity and memory -- A novel conditional knockout strategy applied to serotonin receptors -- Conditional mouse models for Friedreich Ataxia, a neurodegenerative disorder associating cardiomyopathy -- Animal models in cardiovascular diseases: new insights from conditional models -- Conditional animal models for the study of lipid metabolism and lipid disorders -- Conditional mouse models to study developmental and pathophysiological gene function in muscle -- Analysis of calcuim channels by conditional mutagenesis -- Conditional mutagenesis of G-protein coupled receptors and G-proteins -- Contribution of targeted conditional somatic mutagenesis to deciphering retinoid X receptor functions and to generating mouse models of human diseases.

Prologue: The dangerous difference (1778-1954) -- Bk. 1. The sanction of the victim (1954-1969) -- Bk. 2. Interrogations (1969-1975) -- Bk. 3. Trials (1975-1976) -- Bk. 4. The family (1977-1980) -- Bk. 5. Lesbian vampires of Bavaria (1981-1985) -- Bk. 6. HOMOVAC (1986-1990) -- Epilogue: Promises to keep.

The Hungarian congenital abnormality registry (HCAR) -- Certain infectious and parasitic diseases -- Neoplasms -- Diseases of the blood and blood-forming organs -- Endocrine, nutritional and metabolic diseases -- Mental and behavioural disorders -- Diseases of the nervous system -- Diseases of the eye and adnexa -- Diseases of the ear and the mastoid process -- Diseases of the circulatory system -- Diseases of the respiratory system -- Diseases of the digestive system -- Diseases of the skin and subcutaneous tissue -- Diseases of the musculoskeletal system and connective tissue -- Diseases of the urinary tract -- Diseases of the genital organs -- Pregnancy, childbirth, and the puerperium -- Congenital malformations, deformations, and chromosomal abnormalities -- Association of maternal diseases during pregnancy with higher risk of congenital abnormalities (CAs) in their children -- Associations of maternal diseases with higher risk for preterm birth (PB) and low birth weight (LBW) newborns.

The fetal circulation -- Perinatal and postnatal changes in the circulation -- Oxygen uptake and delivery -- Functional assessment -- Prenatal and postnatal pulmonary circulation -- The ductus arteriosus and persistent patency of the ductus arteriosus -- Ventricular septal defect -- Atrial septal defect : partial anomalous drainage of pulmonary veins -- Atrioventricular septal defect -- Bicuspid aortic valve and aortic stenosis -- Aortic atresia, mitral atresia, and hypoplastic left ventricle -- Aortic arch obstruction -- Total anomalous pulmonary venous connection -- Pulmonary stenosis and atresia with ventricular septal defect (tetralogy of Fallot) -- Pulmonary stenosis and atresia with intact ventricular septum -- Tricuspid atresia and hypoplastic right ventricle -- Ebstein malformation of the tricuspid valve -- Aortopulmonary transposition -- Truncus arteriosus communis.

Genomic approaches in genetic research for endocrine diseases / Ravazzolo, R. -- Genetic defects of the growth-hormone-IGF axis associated with growth hormone insensitivity / Woods, K. -- Late effects of disturbed IGF signaling in congenital diseases: intrauterine and postnatal growth retardation / Cianfarani, S. ... [et al.] -- Growth hormone receptor polymorphisms: controversies and outcome of growth hormone treatment / Buzi, F. ... [et al.] -- Genetic disorders involving adrenal development / Lin, L., Ferraz-de-Souza, B., Achermann, J.C. -- Early management and gender assignment in disorders of sexual differentiation / Hughes, I.A -- Prenatal and early postnatal treatment of congenital adrenal hyperplasia / Ghizzoni, L. ... [et al.] -- Neonatal diabetes: the role of KCNJ11 (Kir6.2) / Tammaro, P. -- Diagnosis of neonatal and infancy-onset diabetes / Barbetti, F. -- Management of neonatal and infancy-onset diabetes mellitus / Søvik, O. ... [et al.] -- Insights in congenital hyperinsulinism / Hussain, K. -- A clinical approach to severe insulin resistance / Savage, D.B. ... [et al.] -- Inherited endocrine diseases involving G proteins and G protein-coupled receptors / Spiegel, A.M. -- Stem cells: from animal research to clinical applications / Redi, C.A. ... [et al.].

Introduction to CT scan and MRI; Anomalous systemic venous connections; Anomalous pulmonary venous connections; Atrial septal defect; Unroofed coronary sinus; Atrioventricular septal defect; Ventricular septal defect; Tetralogy of Fallot; Tetralogy of Fallot with absent pulmonary valve; Pulmonary atresia with intact ventricular septum; Ebstein's anomaly; Patent ductus arteriosus; Left ventricular outflow tract obstruction; Aortic coarctation; Aortic arch interruption; Complete transposition of the great arteries; Hypoplastic left heart syndrome; Cor triatriatrum; Tricuspid atresia.

Historical perspective / Joseph K. Perloff -- National and international scope / Joseph K. Perloff, Amy Verstappen -- Specialized facilities for adults with congenital heart disease / Joseph K. Perloff, Pamela D. Miner, Linda Houser -- Survival patterns without cardiac surgery or interventional catheterization : a narrowing base / Joseph K. Perloff -- Survival patterns after cardiac surgery or interventional catherterization : a broadening base / Joseph K. Perloff, Mark D. Plunkett -- Echocardiography in anatomic imaging and hemodynamic evaluation of adults with congenital heart disease / John S. Child -- Cardiac magnetic resonance imaging and computed tomography in the assessment of adult congenital heart disease / Jamil Aboulhosn, Howard Dinh, John P. Finn -- Infective endocarditis and congenital heart disease / John S. Child, David A. Pegues, Joseph K. Perloff -- Management of pregnancy and contraception in congenital heart disease / John S. Child, Koseph K. Perloff, Brian Koos --Genetics, epidemiology, and counseling / Fabian Chen, Emmanuèle Délot, Joseph K. Perloff -- Exercise and athletics in adults with congenital heart disease / Jamil Aboulhosn, Joseph K. Perloff -- Cyanotic congenital heart disease : a multisystem disorder / Joseph K. Perloff -- Psychiatric and psychosocial disorders in congenital heart disease / Barry H. Guze, Elisa A. Moreno, Joseph K. Perloff -- Neurological disorders / Joseph K. Perloff, Jerffrey L. Saver -- Cardiac surgery in adults with congenital heart disease : Operation and reoperation / Daniel Marelli ... [et al.] -- Prosthetic materials : selection, use, and long-term effects / Mark D. Plunkett, Joseph K. Perloff -- Cardiac transplantation in patients with congenital heart disease / Jon A. Kobashigawa, Daniel Marelli -- Transcatheter interventions in adults with congenital heart disease / Jamil Aboulhosn, Daniel Levi, John W. Moore --Noncardiac surgery / Joseph K. Perloff, Michael Sopher -- Residua and sequelae : a perspective / Joseph K. Perloff -- Residua and sequelae involving cardiac valves / Joseph K. Perloff, Mark D. Plunkett -- Electrophysiologic abnormalities : unoperated occurrence and postoperative residua and sequelae / Kalyanam Shivkumar, Joseph K. Perloff -- Myocardial growth and the development and regression of increased ventricular mass / Joseph K. Perloff.

Genetics of cardiac septation defects and their pre-implantation diagnosis / Deborah A. McDermott, Craig T. Basson, and Cathy J. Hatcher -- Molecular and genetic aspects of DiGeorge/velocardiofacial syndrome / Deborah A. Driscoll -- Mutation screening for the genes causing cardiac arrhythmias / Jeffrey A. Towbin -- Mutation analysis of the FBN1 gene in patients with Marfan syndrome / Paul Coucke, Petra Van Acker, and Anne De Paepe -- Mutation analysis of PTPN11 in Noonan syndrome by WAVE / Navaratnam Elanko and Steve Jeffery -- Williams-Beuren syndrome diagnosis using fluorescence in situ hybridization / Lucy R. Osborne, Ann M. Joseph-George, and Stephen W. Scherer -- Congenital heart disease: molecular diagnostics of supravalvular aortic stenosis / May Tassabehji and Zsolt Urban -- "Chip"ping away at heart failure / J. David Barrans and Choong-Chin Liew --Molecular diagnostics of catecholaminergic polymorphic ventricular tachycardia using denaturing high-perfomance liquid chromatography and sequencing / Alex V. Postma, Zahurul A. Bhuiyan, and Hennie Bikker -- Mutation detection in tumor suppressor genes using archival tissue specimens / Aristotelis Astrinidis and Elizabeth Petri Henske -- Friedreich ataxia: detection of GAA repeat expansions and frataxin point mutations / Massimo Pandolfo -- The cardiovascular manifestations of Alagille syndrome and JAG1 mutations / Elizabeth Goldmuntz, Elizabeth Moore, and Nancy B. Spinner -- Array analysis applied to malformed hearts: molecular dissection of tetralogy of Fallot / Silke Sperling -- DNA mutation analysis in heterotaxy / Stephanie M. Ware -- Use of denaturing high-performance liquid chromatography to detect mutations in pediatric cardiomyopathies / Amy J. Sehnert.

Introduction -- Deformities of the anterior thoracic wall -- Diagnostics -- Aspects of indication setting for selection of individual therapy and informed consent -- Therapy -- Special techniques in the funnel chest deformity -- Special techniques in the keel chest deformity -- Special techniques in pectus arcuatum and mixed deformities -- Special aspects in females -- Special technique in the Poland syndrome -- Surgery of other congenital anomalies of the anterior thoracic wall -- Complications, special problems -- Actual technical improvements, future aspects -- Final conclusions.

Conductive polymers as organic nanometals -- Conducting polymer fibre for smart fabric and interactive textile applications -- Inkjet printing and patterning of PEDOT-PSS -- Printing organic electronics on flexible substrates -- Light emitting polymers -- Organic electro-optic materials -- Conjugated polymer electronics -- Electrical bistable polymer films and their applications in memory devices -- Electroactive polymers for batteries and supercapacitors -- Conjugated polymer based photovoltaic devices -- Biomedical applications of ICPs -- Biosensors based on conducting electroactive polymers -- Optical biosensors based on conjugated polymers -- Conducting polymers for MEMS and other micro-devices -- Corrosion protection using conducting polymers -- Artificial muscles.

Chapter 1. Constitutive Activity at the Cannabinoid CB1 Receptor and Behavioral Responses / Katherine E. Hanlon, Todd W. Vanderah -- Chapter 2. Detecting Constitutive Activity and Protean Agonism at Cannabinoid-2 Receptor / Massimiliano Beltramo, Rossella Brusa, Isabella Mancini, Paola Scandroglio -- Chapter 3. Modulation of the Constitutive Activity of the Ghrelin Receptor by Use of Pharmacological Tools and Mutagenesis / Jacek Mokrosiński, Birgitte Holst -- Chapter 4. Assessment of Constitutive Activity and Internalization of GPR54 (KISS1-R) / Macarena Pampillo, Andy V. Babwah -- Chapter 5. Assessment of Constitutive Activity in E-Type Prostanoid Receptors / Hiromichi Fujino, Toshihiko Murayama, John W. Regan -- Chapter 6. α1D-Adrenergic Receptors: Constitutive Activity and Reduced Expression at the Plasma Membrane / J. Adolfo García-Sáinz, M. Teresa Romero-Ávila, Luz del Carmen Medina -- Chapter 7. Constitutive Activity of the Histamine H1 Receptor / Saskia Nijmeijer, Rob Leurs, Henry F. Vischer -- Chapter 8. Constitutive Activity of Somatostatin Receptor Subtypes / Anat Ben-Shlomo, Kolja Wawrowsky, Shlomo Melmed -- Chapter 9. Assessment of Homologous Internalization of Constitutively Active N111G Mutant of AT1 Receptor / Mohiuddin Ahmed Bhuiyan, Takafumi Nagatomo -- Chapter 10. Methods to Detect Cell Surface Expression and Constitutive Activity of GPR6 / Balakrishna M. Prasad, Bettye Hollins, Nevin A. Lambert -- Chapter 11. β3-Adrenoceptor Agonists and (Antagonists as) Inverse Agonists: History, Perspective, Constitutive Activity, and Stereospecific Binding / Maria Grazia Perrone, Antonio Scilimati -- Chapter 12. Constitutive Activity of the Lutropin Receptor and Its Allosteric Modulation by Receptor Heterodimerization / Deborah L. Segaloff -- Chapter 13. Assessing Constitutive Activity of Extracellular Calcium-Sensing Receptors In Vitro and in Bone / Wenhan Chang, Melita Dvorak, Dolores Shoback -- Chapter 14. Constitutive Activity of Neural Melanocortin Receptors / Ya-Xiong Tao, Hui Huang, Zhi-Qiang Wang, Fan Yang, Jessica N. Williams, Gregory V. Nikiforovich -- Chapter 15. Measurement of Constitutive Activity of BMP Type I Receptors / David J.J. de Gorter, Maarten van Dinther, Peter ten Dijke --Chapter 16. Probing the Constitutive Activity Among Dopamine D1 and D5 Receptors and Their Mutants / Bianca Plouffe, Jean-Philippe D'Aoust, Vincent Laquerre, Binhui Liang, Mario Tiberi -- Chapter 17. Identification of Gain-of-Function Variants of the Human Prolactin Receptor / Vincent Goffin, Roman L. Bogorad, Philippe Touraine -- Chapter 18. Investigations of Activated ACVR1/ALK2, a Bone Morphogenetic Protein Type I Receptor, That Causes Fibrodysplasia Ossificans Progressiva / Frederick S. Kaplan, Petra Seemann, Julia Haupt, Meiqi Xu, Vitali Y. Lounev, Mary Mullins, Eileen M. Shore -- Chapter 19. Identification and Evaluation of Constitutively Active Thyroid Stimulating Hormone Receptor Mutations / Joaquin Lado-Abeal, Leah R. Quisenberry, Isabel Castro-Piedras -- Chapter 20. Assessment of Constitutive Activity of a G Protein-Coupled Receptor, Cpr2, in Cryptococcus neoformans by Heterologous and Homologous Methods / Chaoyang Xue, Yina Wang, Yen-Ping Hsueh -- Chapter 21. In Vitro and In Vivo Assessment of Mu Opioid Receptor Constitutive Activity / Edward J. Bilsky, Denise Giuvelis, Melissa D. Osborn, Christina M. Dersch, Heng Xu, Richard B. Rothman -- Chapter 22. Constitutively Active μ-Opioid Receptors / Mark Connor, John Traynor -- Chapter 23. Protein Kinase CK2 is a Constitutively Active Enzyme that Promotes Cell Survival: Strategies to Identify CK2 Substrates and Manipulate its Activity in Mammalian Cells / Jacob P. Turowec, James S. Duncan, Ashley C. French, Laszlo Gyenis, Nicole A. St. Denis, Greg Vilk, David W. Litchfield -- Chapter 24. Assessment of CK2 Constitutive Activity in Cancer Cells / Maria Ruzzene, Giovanni Di Maira, Kendra Tosoni, Lorenzo A. Pinna -- Chapter 25. Structural Basis of the Constitutive Activity of Protein Kinase CK2 / Birgitte B. Olsen, Barbara Guerra, Karsten Niefind, Olaf-Georg Issinger -- Chapter 26. Measuring the Constitutive Activation of c-Jun N-terminal Kinase Isoforms / Ryan T. Nitta, Shawn S. Badal, Albert J. Wong -- Chapter 27. Measurement of Constitutive MAPK and PI3K/AKT Signaling Activity in Human Cancer Cell Lines / Kim H.T. Paraiso, Kaisa Van Der Kooi, Jane L. Messina, Keiran S.M. Smalley -- Chapter 28. Constitutive Activity of GPR40/FFA1: Intrinsic or Assay Dependent? / Leigh A. Stoddart, Graeme Milligan -- Chapter 29. Constitutive Activity of TRP Channels: Methods for Measuring the Activity and Its Outcome / Shaya Lev, Baruch Minke -- Chapter 30. Measurement of Orexin (Hypocretin) and Substance P Effects on Constitutively Active Inward Rectifier K+ Channels in Brain Neurons / Yasuko Nakajima, Shigehiro Nakajima -- Chapter 31. Characterization of G Protein-Coupled Receptor Kinase 4 and Measuring Its Constitutive Activity In Vivo / Bradley T. Andresen -- Chapter 32. Voltage-Clamp-Based Methods for the Detection of Constitutively Active Acetylcholine-Gated IK,ACh Channels in the Diseased Heart / Niels Voigt, Samy Makary, Stanley Nattel, Dobromir Dobrev -- Chapter 33. Assaying WAVE and WASH Complex Constitutive Activities Toward the Arp2/3 Complex.

Chapter 1. Identification and Characterization of Steroidogenic Factor-1 Inverse Agonists / Mabrouka Doghman, Franck Madoux, Peter Hodder, Enzo Lalli -- Chapter 2. Assessment of Inverse Agonism for the Angiotensin II Type 1 Receptor / Hiroshi Akazawa, Noritaka Yasuda, Shin-ichiro Miura, Issei Komuro -- Chapter 3. Measurement of Inverse Agonism in β-Adrenoceptors / Carlos A. Taira, Federico Monczor, Christian Höcht -- Chapter 4. Techniques for Studying Inverse Agonist Activity of Antidepressants at Recombinant Nonedited 5-HT2C-INI Receptor and Native Neuronal 5-HT2C Receptors / Mathieu Seimandi, Joël Bockaert, Philippe Marin -- Chapter 5. Differential Inverse Agonism at the Human Muscarinic M3 Receptor / Paola Casarosa, Tobias Kiechle, Remko A. Bakker -- Chapter 6. Ghrelin Receptor: High Constitutive Activity and Methods for Developing Inverse Agonists / Sylvia Els, Annette G. Beck-Sickinger, Constance Chollet -- Chapter 7. Constitutive Activity and Inverse Agonism at the α1a and α1b Adrenergic Receptor Subtypes / Susanna Cotecchia -- Chapter 8. Measurement of Inverse Agonism of the Cannabinoid Receptors / Tung M. Fong -- Chapter 9. Constitutively Active Thyrotropin and Thyrotropin-Releasing Hormone Receptors and Their Inverse Agonists / Susanne Neumann, Bruce M. Raaka, Marvin C. Gershengorn -- Chapter 10. Inverse Agonists and Antagonists of Retinoid Receptors / William Bourguet, Angel R. de Lera, Hinrich Gronemeyer -- Chapter 11. γ-Aminobutyric Acid Type A (GABAA) Receptor Subtype Inverse Agonists as Therapeutic Agents in Cognition / Guerrini Gabriella, Ciciani Giovanna -- Chapter 12. Assays for Inverse Agonists in the Visual System / Masahiro Kono -- Chapter 13. Receptor-Driven Identification of Novel Human A3 Adenosine Receptor Antagonists as Potential Therapeutic Agents / Silvia Paoletta, Stephanie Federico, Giampiero Spalluto, Stefano Moro -- Chapter 14. Inverse Agonist Activity of Steroidogenic Factor SF-1 / Fabrice Piu, Andria L. Del Tredici -- Chapter 15. Methods to Measure G-Protein-Coupled Receptor Activity for the Identification of Inverse Agonists / Gabriel Barreda-Gómez, M. Teresa Giralt, Rafael Rodríguez-Puertas --Chapter 16. Use of Pharmacoperones to Reveal GPCR Structural Changes Associated with Constitutive Activation and Trafficking / Jo Ann Janovick, P. Michael Conn -- Chapter 17. Application of Large-Scale Transient Transfection to Cell-Based Functional Assays for Ion Channels and GPCRs / Jun Chen, Sujatha Gopalakrishnan, Marc R. Lake, Bruce R. Bianchi, John Locklear, Regina M. Reilly -- Chapter 18. Quantification of RNA Editing of the Serotonin 2C Receptor (5-HT2CR) Ex Vivo / Maria Fe Lanfranco, Noelle C. Anastasio, Patricia K. Seitz, Kathryn A. Cunningham -- Chapter 19. Strategies for Isolating Constitutively Active and Dominant-Negative Pheromone Receptor Mutants in Yeast / Mercedes Dosil, James B. Konopka -- Chapter 20. Development of a GPR23 Cell-Based β-Lactamase Reporter Assay / Paul H. Lee, Bonnie J. Hanson -- Chapter 21. Computational Modeling of Constitutively Active Mutants of GPCRs: C5a Receptor / Gregory V. Nikiforovich, Thomas J. Baranski -- Chapter 22. TSH Receptor Monoclonal Antibodies with Agonist, Antagonist, and Inverse Agonist Activities / Jane Sanders, Ricardo Núñez Miguel, Jadwiga Furmaniak, Bernard Rees Smith -- Chapter 23. Current Standards, Variations, and Pitfalls for the Determination of Constitutive TSHR Activity In Vitro / Sandra Mueller, Holger Jaeschke, Ralf Paschke -- Chapter 24. Toward the Rational Design of Constitutively Active KCa3.1 Mutant Channels / Line Garneau, Hélène Klein, Lucie Parent, Rémy Sauvé -- Chapter 25. Fusion Proteins as Model Systems for the Analysis of Constitutive GPCR Activity / Erich H. Schneider, Roland Seifert -- Chapter 26. Screening for Novel Constitutively Active CXCR2 Mutants and Their Cellular Effects / Giljun Park, Tom Masi, Chang K. Choi, Heejung Kim, Jeffrey M. Becker, Tim E. Sparer -- Chapter 27. A Method for Parallel Solid-Phase Synthesis of Iodinated Analogs of the Cannabinoid Receptor Type I (CB1) Inverse Agonist Rimonabant / Alan C. Spivey, Chih-Chung -- Chapter 28. Coexpression Systems as Models for the Analysis of Constitutive GPCR Activity / Erich H. Schneider, Roland Seifert -- Chapter 29. Modeling and Simulation of Inverse Agonism Dynamics / L.J. Bridge -- Chapter 30. Design and Use of Constitutively Active STAT5 Constructs / Michael A. Farrar -- Chapter 31. In Vitro and In Vivo Assays of Protein Kinase CK2 Activity / Renaud Prudent, Céline F. Sautel, Virginie Moucadel, Béatrice Laudet, Odile Filhol, Claude Cochet.

Consumer health informatics / Deborah Lewis, Betty L. Chang, Charles P. Friedman -- Empowered consumers / Patricia Flatley Brennan and Charles Safran -- Tailored health communication / Rita Kukafka -- Design and evaluation of consumer health information web sites / Gunther Eysenbach -- Information delivery methods / James H. Harrison, Jr. -- Delivery of online learning for healthcare consumers / Deborah Lewis -- Qualitative evaluation in consumer health informatics / Bonnie Kaplan -- Patient-to-patient communication: support groups and virtual communities / Gunther Eysenbach -- Electronic patient-centered communication: e-mail and other e-ways to communicate clinically / Daniel Z. Sands -- Consumer health vocabulary / Catherine Arnott Smith and P. Zoë Stavri --Disability informatics / Richard Appleyard -- Ethical issues in consumer health informatics / Holly B. Jimison -- Social informatics and consumer health / Steve Sawyer -- Security of healthcare information systems / Roy Schoenberg -- The National Library of Medicine reaches out to consumers / Joyce E.B. Backus and Eve-Marie Lacroix -- Baby CareLink: collaborative tools to support families / Charles Safran and Denise Goldsmith -- CHOICEs: patients as participants in shared care planning at the point of care / Cornelia M. Ruland -- MedCERTAIN/MedCIRCLE: using semantic web technologies for quality management of health information on the web / Gunther Eysenbach -- The MI-HEART Project / Rita Kukafka, Yves A. Lussier, and James J. Cimino -- CHESS: 10 years of research and development in consumer health informatics for broad populations, including the underserved / David H. Gustafson ... [et al.].

pt. 1. Understanding consumer food choice and acceptance: 1. Integrating consumer responses to food products / H.L. Meiselman -- 2. Sensory perception as a basis of food acceptance and consumption / H. Tuorila -- 3. How does culture affect choice of foods? / P. Rozin -- 4. Psychobiological mechanisms in food choice / M.R. Yeomans -- 5. How do risk beliefs and ethics affect food choice? / A. Saba -- 6. Consumer attitudes to food innovation and technology / M. Siegris -- pt. 2. Determining consumers' food-related attitudes for food product development -- 7. Methods to understand consumer attitudes and motivations in food product development / D. Buck -- 8. Using means-end chains to understand food consumers' knowledge structures / A. Krystallis -- 9. Consumer attitude measures and food product development / K. Bruns and K. G. Grunert -- 10. Measuring consumer expectations to improve food product development / A.V. Cardello -- 11. Boredom and the reasons why some new food products fail / E.P. Koster and J. Mojet -- 12. SensoEmotional optimisation of food products and brands / D. Thomson -- pt. 3. Methods for consumer-led food product development -- 13. Sensory research and consumer-led food product development / H. Stone and J.L. Sidel -- 14. Opportunity identification in new product development and innovation in food product development / E. van Kleef and H.C.M. van Trijp -- 15. Consumer-driven concept development and innovation in food product development / H. Moskowitz -- 16. Consumer testing of food products using children / R. Popper and J.J. Kroll -- 17. The use of just-about-right (JAR) scales in food product development and reformulation / L. Rothman -- 18. Conducting difference testing and preference trials properly for food product development / M. O'Mahony -- 19. Thurstonian probabilistic approaches to new food product development / J.F. Delwiche -- 20. Using auctions to estimate prices and value of food products / Y. Loheac and S. Issanchou-- 21. The use of partial least squares methods in new food product development / M. Martens ... [et al.] -- 22. Case study of consumer-oriented food product development: reduced-calorie foods / J. Bogue and D. Sorenson -- 23. Preference mapping and food product development / H. MacFie.

Examination and grading --Anterior eye examination --Grading scales --Grading morphs --Eyelids --Blinking abnormalities --Eyelid ptosis --Meibomian gland dysfunction --Eyelash disorders --Tear film --Dry eye --Mucin balls --Conjunctiva --Conjunctival staining --Conjunctival redness --Papillary conjunctivitis --Limbus --Limbal redness --Vascularized limbal keratitis --Superior limbic keratoconjunctivitis --Corneal epithelium --Corneal staining --Epithelial microcysts --Epithelial oedema --Epithelial wrinkling --Stromal oedema --Stromal thinning --Deep stromal opacities --Corneal neovascularization --Corneal infiltrative events --Microbial keratitis --Corneal warpage --Corneal endothelium --Endothelial bedewing --Endothelial blebs --Endothelial cell redistribution --Endothelial polymegethism --Grading scales for contact lens complications --Guillon tear film classification system.

"A rude place and an unpolisht man" : William Penn and the nature of Pennsylvania -- "An infancy of government" : population, authority, and the problem of proprietorship -- "A suitable charity or an effectual security" : community, contagion, and the care of strangers -- "A body corporate and politick" : association, interest, and improvement in a provincial city -- "Improvement in every part of the healing art" : transatlantic cultures of medical improvement -- "A fine field for professional improvement" : sites and sources of medical authority in the Revolutionary War -- "In a yielding state" : nervous nationalism in the new republic -- "Those friendly reciprocities" : panic and participation in the age of yellow fever -- "A matter of police" : fever and betrayal in the federal union.

Introduction: Colorectal Surgery - The Specialty --Hemorrhoids --Anal Fissure and Its Management --Anorectal Fistula --The Management of Pilonidal Sinus Disease --Hidradenitis Suppurativa --Pruritus Ani --Anorectal Sexually Transmitted Infections --Colorectal Cancer Screening and Surveillance --Imaging in Colorectal Cancer --Early Colorectal Cancer Management --Colon Cancer: Advantages of the Laparoscopic Approach and the Principles of Enhanced Recovery --Evidence-Based Management of Rectal Cancer --Chemotherapy and Biomarkers --Biomarkers in Colorectal Cancer: Present and Future --Colorectal Liver Metastases --Anal Cancer --Medical Management of Ulcerative Colitis --Surgical Options in Ulcerative Colitis --Surgery for Fulminant Colitis --Failing Pouch --Surgery for Small Bowel Crohn's Disease --Perianal Crohn's Disease --Surgical Nutrition --Diverticular Disease --Assessment and Investigation of Fecal Incontinence and Constipation --Interventions for Fecal Incontinence --The Management of Constipation --Solitary Rectal Ulcer Syndrome and Pelvic Pain --Rectal Prolapse --Acute Colonic Pseudo-obstruction --Colonic Volvulus --Rectovaginal Endometriosis --Stomas --Intensive Care: The Basics --Critical Care Scoring Systems --Surgical Fluid Management --Colonic Bleeding --Fecal Peritonitis --Large Bowel Obstruction --Miscellaneous (Non-IBD) Colitides --Colon and Rectal Trauma --Postoperative Complications.

"Preface In pharmaceutical/clinical development of a test drug or treatment, relevant clinical data are usually collected from subjects with the diseases under study in order to evaluate safety and efficacy of the test drug or treatment under investigation. To provide accurate and reliable assessment, well-controlled clinical trials under valid study design are necessarily conducted. Clinical trial process is a lengthy and costly process, which is necessary to ensure a fair and reliable assessment of the test treatment under investigation. Clinical trial process consists of protocol development, trial conduct, data collection, statistical analysis/interpretation, and reporting. In practice, controversial issues evitably occur regardless the compliance of good statistical practice (GSP) and good clinical practice (GCP). Controversial issues in clinical trials are referred to as debatable issues that are commonly encountered during the conduct of clinical trials. In practice, controversial issues could be raised from, but are not limited to, (1) compromises between theoretical and real/common practices, (2) miscommunication and/or misunderstanding in perception/interpretation among regulatory agencies, clinical scientists, and biostatisticians, and (3) disagreement, inconsistency, miscommunication/misunderstanding, and errors in clinical practice"--Provided by publisher.

Prostate cancer and active surveillance / Abrahamsson, P.A. -- Radical Prostatectomy in the 21th Century: the gold standard for localized and locally advanced prostate cancer / Schostak, M.; Miller, K.; Schrader, M. -- Radiotherapy as primary treatment modality / Sia, M.; Rosewall, T.; Warde, P. -- Combined radiotherapy and hormonal therapy in the treatment of prostate cancer / Boehmer, D. -- Postoperative adjuvant radiotherapy: standard of care? / Bottke, D.; Wiegel, T. -- Adjuvant hormonal treatment: the bicalutamide early prostate cancer program / Wirth, M.P.; Hakenberg, O.W.; Froehner, M. -- Hormone therapy for prostate cancer: immediate initiation / Schostak, M.; Miller, K.; Schrader, M. -- Lymphadenectomy in prostate cancer: radioguided lymph node mapping: an adequate staging method / Winter, A.; Wawroschek, F. -- Radiotherapy in lymph-node positive prostate cancer patients: potentially curable?: single institutional experience regarding outcome and side effects / Goldner, G.; Pötter, R. -- Radiotherapy in biochemical recurrences after surgery for prostate cancer / Hocht, S. ... [et al.] -- Recurrence following radiotherapy / Desgrandchamps, F. -- Secondary hormonal manipulation / Merseburger, A.S. ... [et al.] -- Chemotherapy in hormone-refractory prostate cancer / Wolff, J.M. -- A randomized phase II trial comparing weekly taxotere + prednisone (P) versus prednisone alone in androgen-independent prostate cancer / Fossa, S.D. -- Hormone-refractory and metastatic prostate cancer: palliative radiotherapy / Moser, L.; Schubert, T.; Hinkelbein, W.

Cutaneous lymphomas - radiotherapeutic strategies / Wilson, L.D., Jones, G.W., Smith, B.D. -- The clinical impact of T cell receptor rearrangement analysis in cutaneous T cell lymphoma / Assaf, C. -- Classification of primary cutaneous lymphomas / Assaf, C. ... [et al.] -- Basal cell and squamous cell carcinoma - radiotherapeutic approaches / Panizzon, R.G. -- Kaposi's sarcoma - radiotherapeutic aspects / Niewald, M.; Räbe, C. -- Pathogenesis and clinical manifestation of Kaposi's sarcoma / Geilen, C.C., Husak, R., Steinhoff, M. -- Merkel cell carcinoma - clinical presentation and treatment / Moll, I. -- Merkel cell carcinoma - uncommon and aggressive cutaneous tumour / Greiner, R.H. ... [et al.] -- Potential of radiation therapy in the multimodal management of Merkel cell carcinoma / Becker, G., Bottke, D. --Skin and other reactions to radiotherapy - clinical presentation and radiobiology of skin reactions / Dörr, W. -- Management of skin and related reactions to radiotherapy / Seegenschmiedt, H. -- Malignant melanoma - markers for progression and prognosis in malignant melanoma / Geilen, C.C. ... [et al.] -- Malignant melanoma - sentinel lymph node biopsy and surgical procedures / Kaufmann, R. -- The role of radiotherapy in malignant melanoma / Marnitz, S., Hoecht, S., Hinkelbein, W. -- Malignant melanoma: classification and staging of malignant melanoma / Eigentler, T.K., Garbe, C. -- Malignant melanoma: PET/CT as a staging procedure / Müller, S.P. -- Malignant melanoma - clinical development of peptide-based melanoma vaccines / Schmittel, A. ... [et al.].

Introducing a transdisciplinary approach to applied urban health research -- Benefits and challenges of transdisciplinary research for urban health researchers -- In search of empowering health research for marginalized populations in urban settings: the value of a transdisciplinary approach -- Reducing health disparities experienced by refugees resettled in urban areas: a community-based transdisciplinary intervention model -- The Street Health Report 2007: community-based research for social change -- Safety as a social value: revisiting a participatory case study in Scotland -- Methodological notes on conducting transdisciplinary research -- Collaborative processes in transdisciplinary research -- From complex problems to complex problem-solving: transdisciplinary practice as knowledge translation -- Transdisciplinary training in health research: distinctive features and future directions -- Funding agencies and transdisciplinary research -- Moving forward: the future of transdisciplinary health research.

Cooperation in primates and humans :closing the gap /Carel P. Van Schaik,Peter M. Kappeler --Practicing Hamilton's rule :kin selection in primate groups /Joan B. Silk --Kinship, competence and cooperation in primates/Bernard Chapais --Reciprocal altruism :30 years later /Robert L. Trivers --Simple and complex reciprocity in primates /Frans B.M. de Waal,Sarah F. Brosnan --Reciprocal exchange in chimpanzees and other primates /John C. Mitani --Causes, consequences and mechanisms of reconciliation :the role of cooperation /Filippo Aureli,Colleen Schaffner --Cooperative hunting in chimpanzees :kinship or mutualism? /Christophe Boesch,Hedwige Boesch,Linda Vigilant --Toward a general model for male-male coalitions in primate groups /Carel P. Van Schaik,Sagar A. Pandit,Erin R. Vogel --Cooperative breeding in mammals /Tim Clutton-Brock --Non-offspring nursing in mammals :general implications from a case study on house mice /Barbara König --Monkeys, markets and minds :biological markets and primate sociality /Louise Barrett,S. Peter Henzi --Digging for the roots of trading /Ronald Noë --Reputation, personal identity and cooperation in a social dilemma /Manfred Milinski --Human cooperation from an economic perspective /Simon Gächter,Benedikt Hermann.

Correlations of cellular activities in the nervous system : Physiological and methodological considerations -- Synchronization between sources : Emerging methods for understanding large-scale functional networks in the human brain -- Approaches to the detection of direct directed interactions in neuronal networks -- The phase oscillator approximation in neuroscience : An analytical framework to study coherent activity in neural networks -- From synchronisation to networks : Assessment of functional connectivity in the brain -- The size of neuronal assemblies, their frequency of synchronization, and their cognitive function -- Synchrony in neural networks underlying seizure generation in human partial epilepsies -- Detection of phase synchronization in multivariate single brain signals by a clustering approach -- Denoising and averaging techniques for electrophysiological data -- Dissection of synchronous population discharges in vitro -- Time-frequency methods and brain rhythm signal processing -- Complex network modeling : A new approach to neurosciences.

Multiple components of COPD -- Clinical assessment of COPD -- Physiologic assessment of COPD -- Outcome measures and prognostic markers for COPD -- Management guidelines for chronic obstructive pulmonary disease -- Pharmacological therapy: bronchodilators -- Pharmacological therapy: inhaled corticosteroids -- Pharmacological therapy: novel approaches -- Smoking cessation -- Pulmonary rehabilitation -- Exacerbations of COPD -- Home management issues -- Co-morbidities and systemic effects of COPD -- Non-pharmacological and surgical management of COPD -- Depression and anxiety in COPD: diagnosis and management issues -- Disease management programs for COPD -- General management issues in COPD: sleep, travel, and preoperative management.

Part I: An introduction to coping theory and research / H. Livneh and E. Martz -- Psychodynamic adn cognitive theories of coping / C.L. Radnitz and L. Tiersky -- Hierarchical coping : a conceptual framework for understanding coping within the context of chronic illness and disability / J. Chronister and F. Chan -- The social context of coping / J.F. Kosciulek -- Reauthoring the self : chronic sorrow and posttraumatic stress following the onset of CID / S. Roos and R.A. Neimeyer -- Adaptive tasks and methods of coping with illness and disability / R.H. Moos and C.J. Holahan. Part II: Coping with AIDS : the challenges of an evolving disease / J. Walkup and L. Cramer-Berness -- Coping with arthritis : from vulnerability to resilience / B.W. Smith and J. Dalen -- Coping with burn injury: research summary and a new model of the influence of coping on psychological complications / J.A. Fauerbach, M.G. Bresnick and M.T. Smith -- Coping with cancer : findings on research and intervention studies / S.L. Manne -- Coping with diabetes : psychological determinants of diabetes outcomes / J. Wagner and H. Tennen -- Coping with epilepsy : research and interventions / M. Bishop and C.A. Allen -- Coping with heart disease : implications for prevention and treatment / K.K. Bennett and J.L. Boothby -- Coping with multiple sclerosis : considerations and interventions / K. McNulty -- Coping with chronic pain : a stress-appraisal coping model / B.E. Thorn and K.E. Dixon -- Coping with severe mental illness : a multifaceted approach / S. Kravetz and D. Roe -- Coping with spinal cord injuries : wholeness is a state of mind / E. Martz and H. Livneh -- Coping with traumatic brain injury : existential challenges and managing hope / J.H. Hinkebein and R.C. Stucky -- Appendix of commonly used coping instruments.

Introduction /Henry J. Aaron,William B. Schwartz --Impact of the revolution in biomedical research on life expectancy by 2050 /John T. Potts,William B. Schwartz.Comment byNicholas Wade --Our uncertain demographic future /Henry J. Aaron,Benjamin H. Harris.Comment byStephen Goss --The changing face of health care /Alan M. Garber,Dana P. Goldman --Labor market effects of dramatic longevity improvement /Gary Burtless.Comment byDora L. Costa --The impact of major improvements in life expectancy on the financing of Social Security, Medicare, and Medicaid /John B. Shoven.Comment byWilliam G. Gale --Ethical aspects of major increases in life span and life expectancy /Alexander M. Capron.Comment byMargaret P. Battin --Increased life expectancy: a global perspective /Barry P. Bosworth,Benjamin Keys.Comment byMartin Baily.

History / Franca Buffoni -- Nomenclature and potential functions of copper amine oxidases / Sinéad Boyce ... [et al.] -- Cofactors of amine oxidases : copper ion and its substitution and the 2,4,5-trihydroxylphenylalanine quinone / Shinnichiro Suzuki ... [et al.] -- Copper amine oxidases from plants / Rosaria Medda ... [et al.] -- Soluble copper amine oxidases from mammals / Paola Pietrangeli ... [et al.] -- Membrane-bound copper amine oxidases / Andrew Holt -- Copper amine oxidase genes / Ivo Frébort and Hubert G. Schwelberger -- Mechanism of TPQ biogenesis in prokaryotic copper amine oxidase / Toshihide Okajima and Katsuyuki Tanizawa -- Copper amine oxidase crystal structures / J. Mitchell Guss, Giuseppe Zanotti, and Tiina A. Salminen -- Plasma amine oxidases in various clinical conditions and in apoptosis / Frans Boomsma, Anton H. van den Meiracker, and Antonio Toninello -- Copper amine oxidases in intestinal diseases / Wieslawa Agnieszka Fogel, Ewa Toporowska-Kowalska, and Anna Stasiak -- Copper amine oxidases in adipose tissue-related disorders / Christian Carpéné -- Copper amine oxidases in adhesion molecules in renal pathology and in Alzheimer's disease and VAP-1 in leukocyte migration / Peter Boor ... [et al.] -- Inhibitors of copper amine oxidases : past, present, and future / Marek Šebela and Lawrence M. Sayre -- Pharmacological applications of copper amine oxidases / Emanuela Masini and Laura Raimondi -- Copper amine oxidases as antioxidant and cardioprotective agents / Mircea Alexandru Mateescu and Réginald Nadeau -- Biotechnological aspects of copper amine oxidases / Roberto Stevanato -- Concluding remarks / David M. Dooley.

The development of new digital technologies has led to fundamental changes in the ways that cultural institutions fulfill their public missions of access, preservation, research, and education. Many institutions are developing publicly accessible Web sites that allow users to visit online exhibitions, search collection databases, access images of collection items, and in some cases create their own digital content. Digitization, however, also raises the possibility of copyright infringement. It is imperative that staff in libraries, archives, and museums understand fundamental copyright principles and how institutional procedures can be affected by the law. "Copyright and Cultural Institutions" was written to assist understanding and compliance with copyright law. It addresses the basics of copyright law and the exclusive rights of the copyright owner, the major exemptions used by cultural heritage institutions, and stresses the importance of "risk assessment" when conducting any digitization project. Case studies on digitizing oral histories and student work are also included.

1. Copyright basics -- 2. Copies for users -- 3. Library reserves -- 4. Permissions and licensing -- 5. Performance and display: libraries and other organizations -- 6. Performance and display: nonprofit educational institutions -- 7. Audiovisual works, sound records, and software -- 8. Photographs and graphics -- 9. The Internet and the Web -- 10. Interlibrary loan and document delivery -- 11. Preservation and archiving -- 12. Digitization -- 13. Miscellaneous issues -- Epilogue. Emerging challenges in copyright -- Appendix. When U.S. works pass in the public domain.

History / Jean-Pierre Vidalain and Louis Setiey -- Basic Science / Tarik Aït Si Selmi, Jean-Marc Semay, Valéry Barbour, Michel-Henri Fessy and Michel Bonnin, et al. -- The Corail® Hip Stem / Steve Young, Markus C. Michel, Tarik Aït Si Selmi, Camdon Fary and Jean-Charles Rollier, et al. -- Corail® Outcomes / Scott Brumby -- The Corail Revision Family / Tim Board -- Part II. Approaches, Bearings, Cups and Direction: The ABC ... and D of Corail® -- Approaches / David Beverland -- Bearings / David Beverland -- Cups / David Beverland -- Direction / David Beverland -- Part III. Case Studies -- Case Studies: Pot-Pourri / Tarik Aït Si Selmi -- Part IV. The Next 25 Years -- Medico-Economic Considerations: Money Does Not Buy Happiness / Jens Boldt -- Educational Programme in Eastern Europe: The Russian Experience / Jens Boldt -- Educational Programme from Europe to Asia Pacific: Travelling the Seven Seas / Jens Boldt -- Erratum / Jean-Pierre Vidalain, Tarik Aït Si Selmi, David Beverland, Steve Young and Tim Board, et al.

Comfort / Jeannine M. Brant -- Coping: psychosocial issues / Patricia M. Grimm -- Coping: altered body image and alopecia / Beth A. Freitas -- Coping: cultural issues / Joanne K. Itano -- Coping: survivorship issues and financial concerns / Susan Leigh -- Sexuality / Patricia W. Nishimoto -- Supportive care: dying and death / MargaretJ. Crowley -- Supportive care: rehabilitation and resources / Sue L. Frymark -- Supportive care: support therapies and procedures / Janis M. Petree -- Supportive care: pharmacologic interventions / Robert J. Ignoffo, Carol S. Viele, and Zoe Ngo -- Supportive care: nonpharmacologic interventions / Denise Murray Edwards -- Alterations in mobility, skin integrity, and neurologic status / Jennifer Douglas Pearce -- Myelosuppression / Dawn Camp-Sorrell -- Alterations in nutrition / Marilynn Berendt and Sherri D'Agostino -- Alterations in elimination / Annette W. Kuck and Elisa Ricciardi -- Alterations in ventilation / Leslie V. Matthews -- Alterations in circulation / Kristine Turner Story -- Metabolic emergencies / Barbara Holmes Gobel -- Structural emergencies / Jane C. Hunter -- Biology of cancer and carcinogenesis / Deborah L. Volker -- Immunology / Kristi V. Schmidt --Genetics / Kathleen A. Calzone -- Nursing care of the client with breast cancer / Marjorie Bernice -- Nursing care of the client with lung cancer / Marie Flannery -- Nursing care of the client with cancers of the gastrointestinal tract / Roberta Anne Strohl -- Nursing care of the client with cancers of the reproductive system / Susan Vogt Temple and Cynthia H. Umstead -- Nursing care of the client with cancers of the urinary system / Maureen E. O'Rourke -- Nursing care of the client with skin cancer / Alice J. Longman -- Nursing care of the client with head and neck cancer / Ellen Carr -- Nursing care of the client with cancers of the neurologic system / Shirley J. Kern -- Nursing care of the client with leukemia / Molly J. Moran and Susan Ezzone -- Nursing care of the client with lymphoma or multiple myeloma / Ryan R. Iwamoto -- Nursing care of the client with bone and soft tissue cancers / Ellen Carr -- Nursing care of the client with HIV-related cancers / Theresa A. Moran --Nursing implications of surgical treatment / Thomas J. Szopa -- Nursing implications of radiation therapy / Mary Ellyn Witt -- Nursing implications of biotherapy and molecular targeted therapy / Danielle M. Gale -- Nursing implications of antineoplastic therapy / Susan Vogt Temple and Barbara C. Poniatowski -- Principles of preparation, administration, and disposal of hazardous drugs / Jean M. Ellsworth-Wolk and Jan Hawthorne Maxson -- Nursing implications of hematopoietic stem cell transplantation / Terry Wikle Shapiro -- Complementary and alternative medicines / Paul Jay Ross -- Epidemiology and prevention of cancer / Sharon J. Olsen -- Early detection of cancer / Candis Morrison -- Application of the statement on the scope and standards of oncology nursing practice and evidence-based practice / Linda U. Krebs -- The education process / Patricia Agre -- Legal issues influencing cancer care / Mary Magee Guillatte -- Selected ethical issues in cancer care / Paul Nelson-Marten and Jacqueline J. Glover -- Cancer economics and health care reform / Molly Loney -- Professional issues in cancer care / Dianne N. Ishida.

The Cornea and external eye disease volumes of the series Essentials in Ophthalmology aim to present recent developments regarding the cornea, with a discussion of diagnostic measures and particular emphasis being placed on treatment.

History of topography / Tracy Swartz ... [et al.] -- Anatomy and physiology of the cornea / Keming Yu ... [et al.] -- The optics of the cornea / David Coward, Tracy Swartz, Ming Wang -- Topographic technologies / Tracy Swartz ... [et al.] -- Axial, elevation, and pachymetric mapping / Ilan Cohen ... [et al.] -- Topographical scales / Ralph Chu and Megan Buliano -- Topography of normal cornea / Zuguo Liu, Xiao Yang, and Mei Zhang -- Topographic presentation of common corneal diseases / Zhenpin Zhang -- Pre-refractive surgery evaluation / Guillermo Avalos ... [et al.] -- Post-refractive surgery topographies / Roberto Pinelli -- Posterior corneal changes in refractive surgery / Amar Agarwal ... [et al.] -- Corneal topography and wavefront sensing: complementary tools / Gustavo E. Tamayo and Mario G. Serrano -- Combined wavefront and topography approach to refractive surgery treatments / Noel Alpins and George Stamatelatos -- LaserSight alternatives in topography-based custom ablation / Aleksandar Stojanovic -- Topography-guided corneal refractive treatment: the VISX model / Rejean Munger and Bruce Jackson -- The Magellean mapper / Michael Endl, Claus Fichte, and Jason Zornek -- The iTrace combination corneal topography and wavefront system by Tracey Technologies / Joe S. Wakil, Tom D. Padrick, and Sergey Molebny -- Bausch & Lomb Orbscan II/IIz anterior segment analysis system / Paul M. Karpecki -- Artemis VHF digital ultrasound technology / Dan Z. Reinstein and Ronald H. Silverman -- The Keratron and Keratron Scout corneal topographers / Renzo Mattioli and Nancy K. Tripoli -- The Tomey TMS corneal topographer / Stephen D. Klyce -- Topcon KR-9000PW / Naoyuki Maeda -- Three-dimensional stereo corneal topographic system: the AstraMax / Ming Wang, Shawna Hill, and Tracy Swartz -- Pentacam / Matthias Maus ... [et al.] -- Precisio / Tracy Swartz ... [et al.] -- The future of corneal topography / Arun C. Gulani and Ming Wang.

Healthy Living, p. 1-24 -- Lipids, p. 25-47 -- Diabetes Mellitus, p. 48-67 -- Hypertension, p. 68-91 -- Cardiac Investigations, p. 92-106 -- Coronary Artery Disease, p. 107-150 -- Chronic Stable Angina, p. 151-166 -- Acute Coronary Syndrome, p. 167-198 -- Heart Failure, p. 199-207 -- Arrhythmias, p. 208-212.

Coronary Anatomy / Gonda J. de Jonge, Peter M. A. van Ooijen, Jean-Louis Sablayrolles, Guido Ligabue and Felix Zijlstra -- Invasive Coronary Imaging / Michael R. Rees, Felix Zijlstra, Johan H. C. Reiber, Joan C. Tuinenburg and Gerhard Koning, et al. -- Non-Invasive Coronary Imaging / Thomas G. Flohr, Bernd Ohnesorge, Robert R. Edelman, Debiao Li and Hatem Alkadhi, et al. -- Non-Invasive Measurement of Coronary Atherosclerosis / Wilfred F. A. den Dunnen, Albert J. H. Suurmeijer, Rozemarijn Vliegenthart Proença, Christopher Herzog and Jaap M. Groen, et al. -- Multi-Dimensional Computed Cardiac Visualization / Peter M. A. van Ooijen, Wisnu Kristanto, Gonda J. de Jonge, Caroline Kuehnel and Anja Hennemuth, et al.

Coronavirus genome structure and replication / D.A. Brian and R.S. Baric -- Coronavirus transcription : a perspective / S.G. Sawicki and D.L. Sawicki -- The coronavirus replicase / J. Ziebuhr -- Viral and cellular proteins involved in coronavirus replication / S.T. Shi and M.M.C. Lai -- Coronavirus reverse genetics by targeted RNA recombination / P.S. Masters and P.J.M. Rottier -- Coronavirus reverse genetics and development of vectors for gene expression / L. Enjuanes ... [et al.] -- Reverse genetics of coronaviruses using vaccinia virus vectors / V. Thiel and S.G. Siddell -- Development of mouse hepatitis virus and SARS-CoV infectious cDNA constructs / R.S. Baric and A.C. Sims.

Phylogenetic, structural, and functional relationships between WD and kelch repeat proteins / Andrew M. Hudson and Lynn Cooley -- Diversity of WD repeat proteins / Temple F. Smith -- A brief history of the coronin family / Eugenio L. de Hostos -- Molecular phylogeny and evolution of the coronin gene family / Reginald O. Morgan and M. Pilar Fernandez -- Coronin structure and implications / Bernadette McArdle and Andreas Hofmann -- Coronin : the double-edged sword of actin dynamics / Meghal Gandhi and Bruce L. Goode -- Invertebrate coronins / Maria C. Shina and Angelika A. Noegel -- Evolutionary and functional diversity of coronin proteins / Charles Peter Xavier ... [et al.] -- Role of mammalian coronin 7 in the biosynthetic pathway / Vasily Rybaki -- Coronin 1 in innate immunity / Jean Pieters -- The role of mammalian coronins in development and disease / David W. Roadcap, Christoph S. Clemen, and James E. Bear.

History of OSHA -- OSHA inspection procedures -- Corporate compliance management -- Preparing for an inspection OSHA inspection checklist -- OSHA penalty structure -- Defenses to an OSHA citation -- Criminal sanctions under the OSH act and beyond -- Occupational safety and health review commission -- Occupational safety and health review commission appeal procedures -- Operational compliance -- Multi-employer worksite issues -- Workers' compensation and safety -- Other litigation issues -- Other laws affecting the safety function -- Ethics in the safety profession -- Emerging issues in safety.

Schizophrenia genes: searching for common features, functions, and mechanisms -- Towards a molecular classification of illness: effects of schizophrenia susceptibility loci on clinical symptoms and cognitive function -- Homer: a genetic factor in schizophrenia? -- Neuroregulin-erbB signaling and the pathogenesis of schizophrenia -- Nicotinic cholinergic cortical dysfunction in schizophrenia -- Role for glutamate receptors, transporters, and interacting proteins in cortical dysfunction in schizophrenia -- Cortical circuit dysfunction in the NMDA receptor hypofunction model for the psychosis of schizophrenia -- Alterations in hippocampal function in schizophrenia: its genetic associations and systems implications -- Identifying novel target genes in psychotic disorder network association analyses -- Alterations in cortical GABA neurotransmission in schizophrenia: causes and consequences -- Increased cortical excitability as a critical element in schizophrenia pathophysiology.

Alzheimer's disease -- Assessment -- Counseling the caregiver -- Family counseling -- Ad hoc counseling -- Support groups for the caregiver -- Helping caregivers adapt to change -- Relationship-related issues -- Managing behavioral and psychological symptoms of Alzheimer's disease -- Medical care for the person with Alzheimer's disease -- Caring for the patient living at home -- Residential care -- The end stage of Alzheimer's disease, death, and bereavement.

The United States is a high priority target, and the goal of today's terrorist is body count. Our enemies can kill thousands with just a small amount of chemical or biological agent. This book details the characteristics, actions, identification, and containment of possible agents. With chapters on chemical agents, biological agents, explosive, nuclear, and incendiary devices, the author prepares the first responder to handle everything from re-establishing control and on-scene triage, to monitoring and detection techniques, decontamination, and training resources. It provides step-by-step procedures for recognizing and identifying terrorist incidents. Explores scene security, crime scene, isolation issues and recommended protective equipment and decontamination procedures. Provides guidance for all emergency responders to terrorist incidents, including fire, EMS, and law enforcement.

Foreword / Robert Kupperman, Stephanie Lanz -- Acknowledgments -- Introduction -- 1. What is terrorism, who are terrorists, what do they do? -- 2. Common elements of terrorism -- 3. Terrorism defense planning -- 4. Bomb defense planning -- 5. Hostage situations -- 6. Kidnapping -- 7. Threat of weapons of mass destruction -- 8. Domestic terrorism -- 9. Bomb incidents -- 10. Hostage incidents -- 11. Postblast environment -- 12. Hostage/Kidnapping aftermath -- 13. Interviewing victims -- 14. Role of the commander -- 15. The command post -- 16. A closer look at 9/11 -- Appendix A. Government-sponsored terrorism -- Appendix B. Foreign terrorist organizations (FTOs) -- Index.

Coupled bioluminescent reactions in practice -- Coupled bioluminescent cytotoxicity assays -- The role of coupled bioluminescent assays in kinase screening and study -- Coupled bioluminescent phosphatase assays -- Acetylcholinesterase -- Measurement of nitric oxide synthase activity by coupled bioluminescence -- The coupled bioluminescent pyrophosphorolysis assay -- Coupled luminescent assays of G-protein-coupled receptors -- Coupled bioluminescent protease assays -- Coupled luminescent assays involving aequorin -- Coupled bioluminescent reporter assays -- Coupled bioluminescent assays : regulatory concerns -- Coupled bioluminescent determination of bioburden and sterility -- Environmental applications of coupled bioluminescent assays.

"Trouble in the Beth Israel Hospital Association" -- The formative years -- From little house on the hill to modern institution -- A modern hospital surviving depression and war -- Medicine at the Beth, 1928-1947 -- The modern institution at midcentury -- Medical research at midcentury -- Redefining the Beth's community -- The changing shape of health care.

History and Prospects of Coxiella burnetii Research /Karim E. Hechemy --Phylogenetic Diversity, Virulence and Comparative Genomics /Erin J. van Schaik and James E. Samuel --Defense Mechanisms Against Oxidative Stress in Coxiella burnetii: Adaptation to a Unique Intracellular Niche /Katja Mertens and James E. Samuel --Lipopolysaccharide of Coxiella burnetii /Craig T. Narasaki and Rudolf Toman --Components of Protective Immunity /Guoquan Zhang, Yan Zhang and James E. Samuel --Proteome of Coxiella burnetii /Robert Ihnatko, Edward Shaw and Rudolf Toman --Coxiella Subversion of Intracellular Host Signaling /S. Kauser Hussain and Daniel E. Voth --The Coxiella burnetii Parasitophorous Vacuole /Eric Ghigo, María I. Colombo and Robert A. Heinzen --Coxiella burnetii Secretion Systems /Justin A. McDonough, Hayley J. Newton and Craig R. Roy --Role of Lipids in Coxiella burnetii Infection /Stacey D. Gilk --Axenic Growth of Coxiella burnetii /Anders Omsland --Developmental Biology of Coxiella burnetii /Michael F. Minnick and Rahul Raghavan --Genetic Manipulation of Coxiella burnetii /Paul A. Beare --Role of Innate and Adaptive Immunity in the Control of Q Fever /Christian Capo and Jean-Louis Mege --Immune Response and Coxiella burnetii Invasion /Amira Ben Amara, Yassina Bechah and Jean-Louis Mege --Antigenic Analysis for Vaccines and Diagnostics /Laura R. Hendrix and Chen Chen --Epidemic Q Fever in Humans in the Netherlands /Wim van der Hoek, Gabriëlla Morroy, Nicole H. M. Renders, Peter C. Wever and Mirjam H. A. Hermans, et al. --Coxiella-like Endosymbionts /Jianmin Zhong --Molecular Typing of Coxiella burnetii (Q Fever) /Robert F. Massung, Sally J. Cutler and Dimitrios Frangoulidis.

Mechanisms of embryology -- Early embryonic development -- Early orofacial development -- Pharyngeal arches -- Pharyngeal pouches and pharyngeal grooves-- Bone development and growth -- Calvaria -- Cranial base -- Facial skeleton -- Palate -- Paranasal sinuses -- Mandible -- Temporomandibular joint -- Skull growth : sutures and cephalometrics -- Tongue and tonsils -- Salivary glands -- Muscle development -- Special sense organs -- Development of the dentition (Odontogenesis) -- Craniofacial disorders with known single gene mutations.

Developmental anatomy of craniofacial sutures / Rice, D.P. -- Locate, condense, differentiate, grow and confront: developmental mechanisms controlling intramembranous bone and suture formation and function / Rice, D.P.; Rice, R. -- Mechanical influences on suture development and patency / Herring, S.W. -- Suture neontology and paleontology: the bases for where, when and how boundaries between bones have been established and have evolved / Depew, M.J.; Compagnucci, C.; Griffin, J. -- Single suture craniosynostosis: diagnosis and imaging / Hukki, J.; Saarinen, P.; Kangasniemi, M. -- Clinical features of syndromic craniosynostosis / Rice, D.P. --Genetics of craniosynostosis: genes, syndromes, mutations and genotype-phenotype correlations / Passos-Bueno, M.R. ... [et al.] -- Roles of FGFR2 and twist in human craniosynostosis: insights from genetic mutations in cranial osteoblasts / Marie, P.J.; Kaabeche, K.; Guenou, H. -- Fibroblast growth factor signaling in cranial suture development and pathogenesis / Hajihosseini, M.K. -- Tgf-€ regulation of suture morphogenesis and growth / Rawlins, J.T.; Opperman, L.A. -- The BMP pathway in skull vault development / Maxson, R.; Ishii, M. -- Current treatment of craniosynostosis and future therapeutic directions / Wan, D.C. ... [et al.].

"Following in the tradition of its popular predecessors, the <STRONG>CRC Desk Reference for Nutrition, Third Edition</STRONG> explains hundreds of terms commonly used in medicine, food science, metabolism, physiology, and nutrition. Thoroughly updated and expanded to reflect major advances over the past decade, this reference lists entries alphabetically and even cross-references them when multiple terms are used for the same definition. Each entry is followed either by a definition, paragraph, essay, composition, article, or feature article. Many of the more complex entries are supported with figures or tables. <STRONG>New Material in the Third Edition</STRONG><UL><LI>Gut hormones and their functions</LI><LI>Food intake recommendations </LI><LI>New drugs with nutritional applications</LI><LI>Novel discoveries of transport and messenger proteins</LI><LI>Gene polymorphisms involved in nutritional responses</LI></UL>A compilation of terms of interest to the nutritionist and non-nutritionist, this book is an alphabetical list of medical terms, drugs, biochemical, genetic and physiological terms relevant to understanding the need for and use of nutrients"--Provided by publisher."Preface to the third edition As in the previous editions of this Desk Reference, terms of interest to the nutritionist are listed alphabetically. Included are medical terms, food science terms, metabolic terms, physiologic terms, drug terms, biotechnology terms and nutrition terms. Since Nutrition and Foods are integrated sciences not all of these terms will be useful to all readers. However, there should be a large number useful to many readers. The third edition provides many more terms than were provided in the earlier editions. There have been some notable changes and inclusions that hopefully will make this edition more useful than the earlier ones. A web address has been included to give the reader access to the extensive Tables of Food Composition maintained by USDA. In addition, a web address for Dietary Reference Intakes has been included to again provide the most current recommendations for nutrient intakes. These recommendations are in a state of flux. As the information base expands with respect to nutrient use and need, the DRIs are changed to reflect this newer knowledge. The RDA Table found in the first edition has been omitted, as have the many tables of food composition. Included in this edition are the many drugs that are used to manage nutrition-related conditions. Cardiovascular disease, diabetes, hypertension, obesity, and so forth are diseases that, while incurable, are manageable. Many medical conditions have a nutrient component to their development as well as a genetic component and the major ones are described. Some of the rare genetic diseases relevant to nutrition and metabolism are also listed. Many drugs used in the management of chronic disease are of interest to the nutritionist so these drugs are listed"--Provided by publisher.

Development of the cerebellum -- Structural cerebellar plasticity -- Cell physiological cerebellar plasticity -- Imaging of cerebellar activity -- Oscillations and synchrony in cerebellar cortex and inferior olive -- Cerebellar motor control -- Cerebellar neuro-anatomical organization -- Excitability in cerebellar cortex -- Cerebellar pathology -- Epilogue.

Latinos and the Changing Demographic Landscape: Key Dimensions for Infrastructure Building --Latino Mental Health: Acculturation Challenges in Service Provision -- Building Response Capacity: The Need for Universally Available Language Services -- Increasing Service Parity Through Organizational Cultural Competence -- Building Infrastructure Through Training and Interdisciplinary Collaboration -- Investing in the Future: Expanding Educational Opportunities for First-Generation Latino College Students -- Putting Students to Work: Spanish Community Service Learning as a Countervailing Force -- Serving Latino Families Caring for a Person with Serious Mental Illness -- The Plight of Latino Youth in the Juvenile Justice System: Considerations for Mental Health Treatment -- Promoting the Well-Being of Unaccompanied Immigrant Minors -- Latinos in Rural Areas: Addressing Mental Health Disparities in New Growth Communities -- Life During and After Breast Cancer: Providing Community-based Comprehensive Services to Latinas -- Lessons Learned from HIV Service Provision: Using a Targeted Behavioral Health Approach -- Private Practice with Latinos: Brief Reflections and Suggestions.

Poisoners throughout history -- Types of poisons -- Poisoners -- Victims -- Crime scene investigation -- The forensic autopsy -- Proving poisoning -- Poisoners in court -- Poisoning in fiction -- Conclusion.

Peface : The evolution of crime action profiling -- What is criminal profiling? -- Smoke and mirrors : the illusions of accuracy in criminal profiles -- Rhetoric vs reality : investigating the skills and accuracy of criminal profiling -- The components and processes of criminal profiling -- Defining serial violent crime -- Operational interpretation of the CAP models -- Criminal profiling of serial rape offenses -- Criminal profiling of sexual murder offenses -- Criminal profiling of serial arson offenses -- Offense location patterns : geographic profiles -- Procedural considerations and format guidelines -- Fighting fire with fire -- Understanding descriptive and inferential statistics : a beginner's guide -- Variable and coding tables.

The human factors: errors and skills -- The challenge of acute healthcare -- The nature of error -- The psychology of human action -- Human perception: the way we see things -- Information processing and mental models: world views -- Goals and plans: turning points for success -- Attention: in the focus of consciousness -- Stress -- Strategies for action: ways to achieve good decisions -- The key to success: teamwork -- Speech is golden: communication -- Leadership -- Organizations and human error -- Reliable acute care medicine.

Angela Dawson, M.D., appears to have it all: at the age of thirty-seven, she owns a fabulous New York City apartment, a stunning seaside house on Nantucket, and enjoys the perks of her prosperous lifestyle. But her climb to the top was rough, marked by a troubled childhood, a failed marriage, and the devastating blow of bankruptcy as a primary-care internist. Painfully aware of the role of economics in modern life, particularly in the health-care field, Angela returned to school to earn an MBA. Armed with a shiny new degree and blessed with determination, intelligence, and impeccable timing, Angela founded a start-up company, Angels Healthcare, then took it public. With her controlling interest in three busy specialty hospitals in New York City and plans for others in Miami and Los Angeles, Angela's future looked very bright.Then a surge of drug-resistant staph infections in all three hospitals devastates Angela's carefully constructed world. Not only do the infections result in patient deaths, but the fatalities also cause stock prices to tumble, leaving market analysts wondering if Angela will be able to hold her empire together. New York City medical examiners Laurie Montgomery and Jack Stapleton are naturally intrigued by the uptick in staph-related post-procedure deaths. Aside from their own professional curiosity, there's a personal stake as well: Laurie and Jack are newly married, and Jack is facing surgery to repair a torn ligament at Angels Orthopedic Hospital. Despite Jack's protests, Laurie can't help investigating-opening a Pandora's box of corporate intrigue that threatens not just her livelihood, but her life with Jack as well.Danger in the Hospital! MRSA strikes multiple hospitals-- in Robin Cook's new novel, Critical. This tightly written medical thriller interweaves drug resistance, cross infection, and the perils of postoperative complications in standalone surgicenters. It also juxtaposes the perspective of an orthopedic patient/physician with the business interests of a physician/entrepreneur.

Hemodynamics -- Hemodynamic monitoring -- Support of the failing circulation -- Arrhythmias, pacing, and cardioversion -- Respiratory monitoring -- Airway intubation -- Indications and options for mechanical ventilation -- Practical problems and complications of mechanical ventilation -- Positive end-expiratory and continuous positive airway pressure -- Weaning and discontinuation of mechanical ventilation -- Intensive care unit imaging -- Acid-base disorders -- Fluid and electrolyte disorders -- Blood conservation and transfusion -- Pharmacotherapy -- Nutritional assessment and support -- Analgesia, sedation, and therapeutic paralysis -- General supportive care -- Quality improvement and cost control -- Cardiopulmonary arrest -- Acute coronary syndromes -- Hypertensive emergencies -- Venous thromboembolism -- Oxygenation failure, ARDS, and acute lung injury -- Ventilatory failure -- ICU infections -- Severe sepsis -- Thermal disorders -- Acute kidney injury and renal replacement therapy -- Clotting and bleeding disorders and anticoagulation therapy -- Hepatic failure -- Endocrine emergencies -- Drug overdose and poisoning -- Neurological emergencies -- Chest trauma -- Acute abdomen -- Gastrointestinal bleeding -- Burns and inhalational injury.

Transition from the fetal to the neonatal circulation -- Triage and transport of infants and children with cardiac disease -- Airway control, mechanical ventilation, and respiratory care -- Heart-lung interactions -- Cardiac catheterization -- Echocardiography -- Cardiac anesthesia -- A pharmacokinetic and pharmacodynamic review -- Sedation and analgesia -- Monitoring of the cardiac patient -- The effects of cardiopulmonary bypass following pediatric cardiac surgery -- Nursing care of the pediatric cardiac patient -- Cardiac database and risk factor assessment. Outcomes analysis for congenital cardiac disease -- Patent ductus arteriosus -- Atrial septal defects -- Ventricular septal defects -- Complete atrioventricular septal defects -- Aortopulmonary window -- Tetralogy of Fallot -- Tetralogy of Fallot with absent pulmonary valve -- Tetralogy of Fallot with pulmonary atresia -- Pulmonary atresia with intact interventricular septum -- Pulmonary stenosis -- Left ventricular outflow tract obstruction -- Coarctation of the aorta -- Interrupted aortic arch -- Mitral valve anomalies and related disorders -- Mitral stenosis -- Prosthetic valves -- Hypoplastic left heart syndrome -- Single ventricle. General aspects -- Anomalous pulmonary veins -- Dextro-transposition fo the great arteries -- Congenitally corrected transposition of the great arteries (ccTGA) or Levo-transposition of the great arteries (l-TGA) -- Truncus arteriosus -- Double outlet right ventricle -- Ebstein's disease -- Anomalous coronary arteries -- Aortic valve regurgitation -- Vascular rings and pulmonary sling -- Takayasu arteritis -- Aortic dissection -- Tracheal resection -- Acute pulmonary hypertension -- Chronic pulmonary hypertension -- Acute myocarditis and cardiomyopathies -- Pericardial diseases -- Infective endocarditis -- Cardiac failure -- Shock in the cardiac patient: a brief overview -- Mechanical circulatory support in pediatric cardiac surgery -- Heart transplantation -- Arrhythmias in the intensive care unit -- Pacemakers (temporary and permanent), implantable cardioverter defibrillators (ICDs) and cardiac resynchronization therapy --Discontinuation of life: ethical and legal issues -- Respiratory complications: acute respiratory distress syndrome, chylothorax, diaphragmatic palsy, and functional and respiratory physiotherapy -- Gastrointestinal complications: necrotizing enterocolitis, malrotation, and protein losing enteropathy -- Malnutrition and feeding difficulties: guidelines for enteral and parenteral nutrition -- Hematological aspects: anticoagulation, heparin-induced thrombocytopenia, plasma exchange -- Renal failure and replacement therapy -- Neurological complications: intracranial bleeding, stroke and seizures -- Infections in the cardiac intensive care unit -- Skin protection.

Goals, design, and implementation of critical pathways in cardiovascular medicine /Christopher P. Cannon and Patrick O'Gara --Part I. --Prehospital critical pathways --Prehospital fibrinolysis /Freek W.A. Verheught --Regional transfer programs for primary PCI /David M. Larson and Timothy D. Henry --Public access defibrillation /Joseph P. Ornato --Part II. --Critical pathways in the emergency department --Non-ST elevation ACS in the emergency department /Richard J. Ryan, Christopher P. Cannon, and W. Brian Gibler --Thrombolysis for ST-elevation mi in the emergency department /Joshua M. Kosowsky --Heart failure in the emergency department /W. Frank Peacock --Atrial fibrillation in the emergency department /Ray Bahr --Stroke and TIA /Lee Schwamm --The Role of exercise testing in chest pain units: evolution, application, results /Ezra A. Amsterdam, Deborah B. Diercks, and Samuel D. Turnipseed --Part III --Critical pathways in the hospital --Critical pathway for non-ST elevation ACS /Christopher P. Cannon and Patrick T. O'Gara --Primary PCI /Amr E. Abbas and Cindy L. Grines --Primary PCI at community hospitals without on-site cardiac surgery /Nancy Sinclair and Thomas P. Wharton, Jr. --Approach to the patient with complicated myocardial infarction /Richard C. Becker --Cardiac catheterization and percuraneous coronary intervention /Jeffrey J. Popma --Pathways for coronary artery bypass surgery /Rashid M. Ahmad, Frances Wadlington, Tiffany Street, James P. Greelish, Jorge M. Balaguer, and John G. Byrne --Acute aortic syndromes /Piotr Sobieszcyk and Patrick O'Gara --Intensive management of hyperglycemia in ACS /Vera T. Fajtova --Management of atrial fibrillation and atrial flutter /Eyal Herzog and Jonathan S. Steinberg --Heart failure /Greg Fonarow --Device therapy in patients with heart failure /Peter J. Zimetbaum and Eli V. Gelfand --Venous thromboembolism /Samuel Z. Goldhaber --Part IV. --Critical pathways in the outpatient setting /--Hyperlipidemia /Frederick F. Samaha and Daniel J. Rader --Diabetes and metabolic syndrome /Emily Deborah Szmuilowicz and Merri Pendergrass --Hypertension /Michael A. Weber --Smoking cessation /Beth C. Bock --Secondary prevention overview /Sidney Smith --Overview of the AHA "get with the guidelines" programs /Yuling Hong, Kenneth A. LaBresh --Cardiac rehabilitation in the post myocardial infarction patient /Daniel E. Forman.

Genetic factors in ethnic disparities in health / Richard S. Cooper -- Race/ethnicity, socioeconomic status, and health / Eileen M. Crimmins, Mark D. Hayward and Teresa E. Seeman -- The role of social and personal resources in ethnic disparities in late-life health / Carlos F. Mendes de Leon and Thomas A. Glass -- What makes a place healthy? neighborhood influences on racial and ethnic disparities in health over the life course / Jeffrey D. Morenoff and John W. Lynch --Racial and ethnic disparities in health behaviors: a challenge to current assumptions / Marilyn A. Winkleby and Catherine Cubbin -- Cumulative psychosocial risks and resilience: a conceptual perspective on ethnic health disparities in late life / Hector F. Myers and Wei-Chin Hwang -- Significance of perceived racism: toward understanding ethnic group disparities in health, the later years / Rodney Clark -- A neurovisceral integration model of health disparities in aging / Julian F. Thayer and Bruce H. Friedman -- Geography and racial health disparities / Amitabh Chandra and Jonathan S. Skinner -- Behavioral health interventions: what works and why? / David M. Cutler -- Ethnic disparities in aging health: what can we learn from the United Kingdom? / James Y. Nazroo -- An exploratory investigation into racial disparities in the health of older South Africans / Debbie Bradshaw ... [et al.].Racial and ethnic identification, official classifications, and health disparities / Gary D. Sandefur, Mary E. Campbell, and Jennifer Eggerling-Boeck -- Racial and ethnic disparities in health and mortality among the U.S. elderly population / Robert A. Hummer, Maureen R. Benjamins, and Richard G. Rogers -- Ethnic differences in dementia and Alzheimer's disease / Jennifer J. Manly and Richard Mayeux -- The life-course contribution to ethnic disparities in health / Clyde Hertzman -- Selection processes in the study of racial and ethnic differentials in adult health and mortality / Alberto Palloni and Douglas C. Ewbank -- Immigrant health: selectivity and acculturation / Guillermina Jasso ... [et al.] --

Etiology / Marzia Marrollo, Alessandro Armuzzi and Fabio Zannoni -- Epidemiology / Marina Rizzi -- Genetics / Marco Castori and Paola Grammatico -- The Role of the Pathologist in the Management of Patients with Crohn's Disease / Roberto Pisa, Maria Cristina Macciomei and Alvaro Leone -- Clinical Presentation / Anna Kohn, Caterina Maria Camastra, Rita Monterubbianesi and Marina Rizzi -- Diagnostic and Therapeutic Role of Endoscopy / Arnaldo Andreoli, Patrizia Meddi, Paolo Pantanella and Antonio Tesi -- Laboratory Tests / Giuseppe Famularo and Giovanni Minisola -- Imaging / Loredana Adami, Maurizio Atzori, Paola Cerro, Andrea Cortese and Pasquale Ialongo, et al. -- Diagnosis of Anorectal Disease / Pasquale Ialongo, Loredana Adami, Maurizio Atzori, Cesare Hassan and Andrea Cortese, et al. -- Role of Interventional Radiology / Francesco Colucci, Paolo Agresti, Stefano Pieri, Maurizio Morucci and Lorenzo de' Medici -- Standard Therapeutic Approach / Roberto Mangiarotti -- New Therapies / Maria Lia Scribano and Maria Laura Annunziata -- Cell and Stem-Cell Therapies of Crohn's Disease and Complications / Luca Pierelli, Sergio Rutella and Giuseppina Bonanno -- Surgical Treatment / Roberto Tersigni -- Crohn's Disease in Children / Salvatore Cucchiara and Laura Stronati -- Perianal Disease / Luciano Alessandroni -- Crohn's Disease and Pregnancy / Claudio Donadio, Rocco Cosintino, Giuliano Rigon, Claudio Donadio and Fabrizio Signore -- Rheumatological Manifestations of Crohn's Disease / Giovanni Minisola and Giuseppe Famularo -- Cutaneous Manifestations / Luciano Alessandroni and Andrea Scotti -- Ocular Manifestations / Vincenzo Petitti and Stefano Tamburi -- Hepatopathologies / Leone Nauri -- Infectious Complications / Nicola Petrosillo and Cecilia M. J. Drapeau -- Kidney Disease / Margherita Rosa and Salvatore Di Giulio -- Crohn's Disease and Cancer / Fabio Calabrò and Cora N. Sternberg -- Crohn's Disease and Malignant Lymphomas / Valerio Zoli, Anna Proia and Ignazio Majolino -- Psychological and Social Aspects / Susan Levenstein and Vilma Varvo.

Signal transduction in DC differentiation: winged messengers and Achilles' heel / Inna Lindner ... [et al.] -- Shaping naive and memory CD8+ T cell responses in pathogen infections through antigen presentation / Gabrielle T. Belz ... [et al.] -- Understanding the role of innate immunity in the mechanism of action of the live attenuated yellow fever vaccine 17D / Troy D. Querec and Bali Pulendran -- The function of local lymphoid tissues in pulmonary immune responses / Juan Moyron-Quiroz ... [et al.] -- The yin and yang of adaptive immunity in allogeneic hematopoietic cell transplantation: donor antigen-presenting cells can either augment or inhibit donor T cell alloreactivity / Jian-Ming Li and Edmund K. Waller -- It's only innate immunity but I like it / Emanuela Marcenaro ... [et al.] -- Innate tumor immune surveillance / Mark J. Smyth, Jeremy Swann, and Yoshihiro Hayakawa -- Regulation of adaptive immunity by cells of the innate immune system: bone marrow natural killer cells inhibit T cell proliferation / Prachi P. Trivedi ... [et al.] -- Induction and maintenance of CD8+ T cells specific for persistent viruses / Ester M.M. van Leeuwen, Ineke J.M. ten Berge, and René A.W. van Lier -- Germinal center-derived B cell memory / Craig P. Chappell and Joshy Jacob -- CD28 and CD27 costimulation of CD8+ T cells: a story of survival / Douglas V. Dolfi and Peter D. Katsikis -- CD38: an ecto-enzyme at the crossroads of innate and adaptive immune responses / Santiago Partida Sánchez ... [et al.] -- Vascular leukocytes: a population with angiogenic and immunosuppressive properties highly represented in ovarian cancer / George Coukos ... [et al.] -- CD4+ T cells cooperate with macrophages for specific elimination of MHC class II-negative cancer cells / Alexandre Corthay -- Receptors and pathways in innate antifungal immunity: the implication for tolerance and immunity to fungi / Teresa Zelante ... [et al.].

Protective effects of type1 interferon in models of intestinal inflammation / Jongdae Lee ... [et al.] -- NK/DC complot / Emanuela Marcenaro ... [et al.] -- Detection of microbes by natural killer T cells / Yuki Kinjo, Mitchell Kronenberg -- Ontogeny of the secondary antibody response, origins and clonal diversity / Craig P. Chappell, Joseph Dauner, Joshy Jacob -- Role of PI3K signalling in the B cell response to antigen / Daniel J. Hodson, Martin Turner -- CD28, old dog, new tricks / Jayakumar R. Nair, Cheryl Rozanski, Kelvin P. Lee -- Initial TCR transgenic precursor frequency alters functional behaviour of CD8 T cells responding to acute infection / Thomas Wirth, John T. Harty -- Effects of cancer immunotherapy regimens on primary vs. secondary immune responses and the potential impact on long-term antitumor responses / Kory L. Alderson, William J. Murphy -- New insights into classical costimulation of CD8+ T cell responses / Christine M. Bucks, Peter D. Katsikis -- Peripheral tolerance induction by lymph node stroma / Erika D. Reynoso, Je-Wook Lee, Shannon J. Turley.

Is transcription the dominant force during dynamic changes in gene expression? -- MicroRNAs: key components of immune regulation -- KIR/HLA: genetic clues for a role of NK cells in the control of HIV -- Natural killer cell licensing during viral infection -- Bridging innate NK cell functions with adaptive immunity -- Control of innate immunity by memory CD4 T cells -- Strategies and implications for prime-boost vaccination to generate memory CD8 T cells -- Blimp1: driving terminal differentiation to a T -- New role for myeloid HO-1 in the innate to adaptive crosstalk and immune homeostasis -- Impact of differential glycosylation on IgG activity -- Murine model of chronic respiratory inflammation -- Incorporation of innate immune effector mechanisms in the formulation of a vaccine against HIV-1 -- Influenza vaccines: what do we want and how can we get it?

Historical perspective. 3D reconstruction from electron micrographs: a personal account of its development / David DeRosier -- Chapter 1. Preparation of 2D crystals of membrane proteins for high-resolution electron crystallography data collection / Priyanka D. Abeyrathne ... [et al.] -- Chapter 2. Helical crystallization of soluble and membrane binding proteins / Elizabeth M. Wilson-Kubalek, Joshua S. Chappie, Christopher P. Arthur -- Chapter 3. Plunge freezing for electron cryomicroscopy / Megan J. Dobro ... [et al.] -- Chapter 4. A Practical guide to the use of monolayer purification and affinity grids / Deborah F. Kelly, Danijela Dukovski, Thomas Walz -- Chapter 5. GraFix: stabilization of fragile macromolecular complexes for single particle cryo-EM / Holger Stark -- Chapter 6. Cryonegative staining of macromolecular assemblies / Sacha De Carlo, Holger Stark -- Chapter 7. Liposomes on a streptavidin crystal: a system to study membrane proteins by cryo-EM / Liguo Wang, Fred J. Sigworth -- Chapter 8. Micromanipulator-assisted vitreous cryosectioning and sample preparation by high-pressure freezing / Mark S. Ladinsky -- Chapter 9. Site-specific biomolecule labeling with gold clusters / Christopher J. Ackerson, Richard D. Powell, James F. Hainfeld -- Chapter 10. How to operate a cryo-electron microscope / Jingchuan Sun, Huilin Li -- Chapter 11. Collecting electron crystallographic data of two-dimensional protein crystals / Richard K. Hite ... [et al.] -- Chapter 12. Automated data collection for electron microscopic tomography / Shawn Q. Zheng, J.W. Sedat, D.A. Agard -- Chapter 13. Correlated light and electron cryo-microscopy / Ariane Briegel ... [et al.] -- Chapter 14. Phase plates for transmission electron microscopy / Radostin Danev, Kuniaki Nagayama -- Chapter 15. Radiation damage in electron cryomicroscopy / Lindsay A. Baker, John L.

Chapter 1. Fundamentals of three-dimensional reconstruction from projections / Pawel A. Penczek -- Chapter 2. Image restoration in cryo-electron microscopy / Pawel A. Penczek -- Chapter 3. Resolution measures in molecular electron microscopy / Pawel A. Penczek -- Chapter 4. 3D reconstruction from 2D crystal image and diffraction data / Andreas D. Schenk ... [et al.] -- Chapter 5. Fourier-Bessel reconstruction of helical assemblies / Ruben Diaz, William J. Rice, David L. Stokes -- Chapter 6. Reconstruction of helical filaments and tubes / Edward H. Egelman -- Chapter 7. Three-dimensional asymmetric reconstruction of tailed bacteriophage / Jinghua Tang, Robert S. Sinkovits, Timothy S. Baker -- Chapter 8. Single particle analysis at high resolution / Yao Cong, Steven J. Ludtke -- Chapter 9. The Orthogonal tilt reconstruction method / Andres Leschziner -- Chapter 10. An Introduction to maximum-likelihood methods in cryo-EM / Fred J. Sigworth ... [et al.] -- Chapter 11. Classification of structural heterogeneity by maximum-likelihood methods / Sjors H.W. Scheres -- Chapter 12. Methods for three-dimensional reconstruction of heterogeneous assemblies / Elena V. Orlova, Helen R. Saibil -- Chapter 13. Alignment of cryo-electron tomography datasets / Fernando Amat ... [et al.] -- Chapter 14. Correcting for the Ewald sphere in high-resolution single-particle reconstructions / Peter A. Leong ... [et al.] -- Chapter 15. Software tools for molecular microscopy: an open-text wikibook / Neil R. Voss ... [et al.].

Chapter 1. Analyses of subnanometer resolution cryo-EM density maps / Matthew L. Baker ... [et al.] -- Chapter 2. Methods for segmentation and interpretation of electron tomographic reconstructions / Niels Volkmann -- Chapter 3. Integration of cryo-EM with atomic and protein-protein interaction data / Friedrich Förster, Elizabeth Villa -- Chapter 4. Unified data resource for cryo-EM / Catherine L. Lawson -- Chapter 5. Electron crystallography and aquaporins / Andreas D. Schenk ... [et al.] -- Chapter 6. Cryoelectron microscopy applications in the study of tubulin structure, microtubule architecture, dynamics and assemblies, and interaction of microtubules with motors / Kenneth H. Downing, Eva Nogales -- Chapter 7. Helical crystallization of two example membrane proteins: MsbA and the Ca2+-ATPase / John Paul Glaves ... [et al.] -- Chapter 8. Multiparticle cryo-EM of ribosomes / Justus Loerke, Jan Giesebrecht, Christian M.T. Spahn -- Chapter 9. Single-particle electron microscopy of animal fatty acid synthase: describing macromolecular rearrangements that enable catalysis / Edward J. Brignole, Francisco Asturias -- Chapter 10. Tomography of actin cytoskeletal networks / Dorit Hanein -- Chapter 11. Visual proteomics / Friedrich Förster, Bong-Gyoon Han, Martin Beck -- Chapter 12. Cryoelectron tomography of eukaryotic cells / Asaf Mader, Nadav Elad, Ohad Medalia -- Chapter 13. 3D visualization of HIV virions by cryoelectron tomography / Jun Liu, Elizabeth R. Wright, Hanspeter Winkler -- Chapter 14. Automation in single-particle electron microscopy: connecting the pieces / Dmitry Lyumkis ... [et al.].

History of cardiac cryosurgery and cryoablation / Daniel L. Lustgarten -- Mechanisms of cryoablation / Kristi K. Snyder ... [et al.] -- Factors that determinine cryolesion formation and cryolesion characteristics / Audrius J. Bredikis and David J. Wilber -- Canine model of esophageal injury during atrial fibrillation ablation : comparison of cryothermal, radiofrequency, and ultrasound ablation injury / Hiroshi Nakagawa ... [et al.] -- Cryoablation effects on pulmonary veins in experimental settings / Mauricio Arruda ... [et al.] -- Cryoablation effects on coronary arteries and veins / Audrius J. Bredikis -- Medtronic cryocath technology / Jeffrey Silver ... [et al.] -- Boston scientific technology / Victoria Carr-Brendel and Joann Heberer -- Evolving concepts : near-critical cooling-based technologies / Peter J. Littrup and Alex Babkin -- Reversible effects of cryoablation and atrioventricular node modification / Frédéric Franceschi, Marc Dubuc, and Paul Khairy -- AVNRT cryoablation and comparison with RF ablation / Luc Jordaens ... [et al.] -- Cryoablation of septal accessory pathways / Felipe Atienza and Jesus Almendral -- Cryoablation of atrial flutter / Peter S. Andrew and Annibale S. Montenero -- Focal cryoablation of atrial fibrillation / Chung-Wah Siu and Hung-Fat Tse -- Balloon-based cryoablation of atrial fibrillation / Thomas Neumann and Malte Kuniss -- Cryocatheter ablation of ventricular tachycardia / Heinz T. Pitschner and Damir Erkapic -- Role of cryoablation for superior vena cava isolation and ablation of inappropriate sinus tachycardia / John Roshan ... [et al.] -- Cryoablation in pediatrics / Bryan Canon -- Endocardial cryoablation of atrial fibrillation / Fiorenzo Gaita ... [et al.] -- Cryosurgery for ventricular tachycardia / Jean-Marc Frapier ... [et al.].

General biology / Ronald Fayer -- Genomics / Jessica C. Kissinger -- Biochemistry / Guan Zhu -- Epidemiology / Gordon Nichols -- Molecular epidemiology / Lihua Xiao and Una M. Ryan -- Diagnostics / Huw Smith -- Immune responses / Vincent McDonald -- Clinical disease and pathology / Cirle Alcantara Warren and -- Richard l. Guerrant -- Prophylaxis and chemotherapy / Heather D. Stockdale, Jennifer A. Spencer, and Byron L. Blagburn -- Foodborne transmission / Ynes R. Ortega and Vitaliano A. Cama -- Waterborne: drinking water / Jennifer L. Clancy and Thomas M. Hargy -- Waterborne: recreational water / Michael Beach -- Waste management / Dwight D. Bowman -- Fish, amphibians and reptiles / Thaddeus Graczyk -- Birds / Una Ryan and Lihua Xiao -- Zoo and wild mammals / Olga Matos -- Companion animals / Mónica Santín and James M. Trout -- Livestock / Mónica Santín and James M. Trout -- Animal models / Saul Tzipori and Giovanni Widmer -- In vitro cultivation / Michael J. Arrowood.

Model and molecule. -- An overview of protein crystallography. -- Protein crystals. -- Collecting diffraction data. -- From diffraction data to electron density. -- Obtaining phases. -- Obtaining and judging the molecular model. -- A user's guide to crystallographic models. -- Other diffraction methods. -- Other kinds of macromolecular models. -- Tools for studying macromolecules. -- Appendix: Viewing stereo images.

Principles of computed tomographic angiography -- Principles of magnetic resonance angiography -- Conventional angiography in the noninvasive era -- Contrast medium administration in computed tomographic angiography -- Contrast medium administration in magnetic resonance angiography -- Postprocessing and data analysis -- Atherosclerosis : epidemiology and pathology -- Atherosclerosis : in vivo characterization -- Thromboembolism -- Vasculitides and connective tissue disorders -- Cerebral arteries and veins -- Cervical vasculature -- Quantifying coronary artery calcium -- Coronary arteries -- Thoracic vascular anomalies -- Pulmonary vasculature -- Thoracic aorta -- Abdominal aorta -- Mesenteric vasculature -- Renal vasculature -- Lower extremities vasculature -- Upper extremities vasculature -- Pediatric techniques and vascular anomalies -- Venous system.

Liver and biliary system -- Pancreas -- Gastrointestinal tract -- Spleen -- Mesentery, omentum, and peritoneum -- Kidneys, ureter, and bladder -- Pelvis -- Retroperitoneum and adrenal glands -- Abdominal wall.

CT of the heart: past, present, and future / William Stanford -- Electron beam CT of the heart / David G. Hill -- Scan techniques for cardiac and coronary artery imaging with multislice CT / Bernd M. Ohnesorge, Brian R. Westerman and U. Joseph Schoepf -- Image reconstruction for ECG-triggered and ECG-gated multi-slice CT / Thomas Flohr and Tinsu Pan -- Phase-correlated image reconstruction without ECG / Marc Kachelriess and Willi A. Kalender -- Radiation dose from CT of the heart / Cynthia H. McCollough -- Coronary calcium screening: an epidemiologic perspective / Christopher J. O'Donnell and Udo Hoffmann -- Coronary calcium scanning: why we should perform it / Axel Schmermund, Stefan Möhlenkamp and Raimund Erbel -- Detection and quantification of coronary calcium with electron beam CT -- Axel Schmermund, Stefan Möhlenkamp and Raimund Erbel -- Detection and quantification of coronary calcium with dual slice CT / Joseph Shemesh --Detection and quantification of calcified coronary plaque with multidetector-row CT / J. Jeffrey Carr -- Coronary calcium scoring with multidetector-row CT: rationale and scoring techniques / Roman Fischbach and David Maintz -- Noninvasive quantification of coronary calcium: quantification methods, scanner types, scan protocols, accuracy, and reproducibility / Stefan Ulzheimer, Kaiss Shanneik and Willi A. Kalender -- CT of the pericardium / Reinhard Groell -- Multidetector-row CT for assessment of cardiac valves / Jürgen K. Willmann and Dominik Weishaupt -- Multislice CT of the heart and great vessels in congenital heart disease patients / Jean-François Paul -- Imaging of cardiac and paracardiac masses and pseudotumors / Bernd J. Wintersperger -- Multidetector-row CT assessment of left-ventricular function / Kai Uwe Juergens and Roman Fischbach -- Imaging intramyocardial microcirculatory function using fast computed tomography / Stefan Möhlenkamp ... [et al.] --Approaches for assessing myocardial viability with multidetector-row CT / Yasushi Koyama and Teruhito Mochizuki -- Anatomy of the coronary arteries and veins in CT imaging / Robert J.M. van Geuns and Filipo Cademartiri -- Techniques and protocols for acquisition and display of contrast-enhanced CT coronary angiography / Christoph R. Becker -- Contrast material injection techniques for CT angiography of the coronary arteries / Filippo Cademartiri and Koen Nieman -- Visualization techniques for contrast-enhanced CT angiography of coronary arteries / Jean-Louis Sablayrolles and Pascal Giat -- CT angiography for assessment of coronary artery anomalies / Steffen C. Froehner ... [et al.] -- Multidetector-row CT for assessment of Kawasaki's disease / Toru Sakuma and Kunihiko Fukuda -- Multidectector-row CT of the coronary arteries for planning of minimally invasive bypass surgery / Christopher Herzog, Selami Dogan and Thomas J. Vogl --CT angiography for assessment of coronary bypass grafts / Marcello De Santis -- Contrast-enhanced electron beam CT and multidetector-row CT in the evaluation of coronary stent patency / Heiko Pump ... [et al.] -- CT angiography for the detection of coronary artery stenosis / Koen Nieman and Filippo Cademartiri -- Complementary use of coronary calcium scoring and CT angiography / Alexander W. Leber -- CT vs magnetic resonance for imaging of the coronary arteries / Armin Huber -- Pathology and pathophysiology of coronary atherosclerotic plaques / Renu Virmani ... [et al.] -- Pathogenesis of the vulnerable atherosclerotic plaque / Masanori Aikawa -- Multidetector-row CT imaging of clinical and preclinical coronary atherosclerosis / Christoph R. Becker -- Multidetector-row CT vs intravascular ultrasound for coronary plaque characterization / Axel Kuettner -- Multidetector-Row CT vs magnetic resonance imaging for coronary plaque characterization / Konstantin Nikolaou, Christoph R. Becker, and Zahi Fayad -- Multidetector-row CT for detection of noncalcified and calcified coronary lesions: clinical significance / Stephen Schroeder.

1. Afghans -- 2. African Americans -- 3. American Indians/Alaskan natives -- 4. Arabs -- 5. Brazilians -- 6. Cambodians (Khmer) -- 7. Central Americans (Guatemalans, Nicaraguans, and Salvadorans) -- 8. Chinese -- 9. Colombians -- 10. Cubans -- 11. Dominicans -- 12. East Indians -- 13. Ethiopians and Eritreans -- 14. Filipinos -- 15. Germans -- 16. Greeks -- 17. Haitians -- 18. Hawaiians -- 19. Hmong -- 20. Iranians -- 21. Irish -- 22. Italians -- 23. Japanese -- 24. Koreans -- 25. Mexicans -- 26. Nigerians -- 27. Pakistanis -- 28. Polish -- 29. Puerto Ricans -- 30. Roma (Gypsies) -- 31. Russians and others from the former Soviet Union -- 32. Samoans -- 33. Vietnamese -- 34. West Indians/Caribbeans -- 35. (Former) Yugoslavians.

D.H. Saklofske, L.G. Weiss, A.L. Beal, and D. Coalson / The Wechsler Scales for Assessing Children's Intelligence: Past to Present -- J. Georgas / Cross-Cultural Psychology, Intelligence and Cognitive Processes -- L.G. Weiss / The WISC-III in the United States -- D.H. Saklofske / Canada -- P. McKeown / United Kingdom -- J. Gregoire / France and French-Speaking Belgium -- M. Schittekatte, W. Kort, W. Resing, G. Vermeir, P. Verhaeghe / The Netherlands and Flemish-Speaking Belgium -- U. Tewes / Germany -- P. Rossmann and U. Schallberger / Austria and German-Speaking Switzerland -- K. Sonnander and B. Ramund / Sweden -- G. Gintiliene and S. Girdzijauskiene / Lithuania -- D. Boben and V. Bucik / Slovenia -- J. Georgas, I.N. Paraskevopoulos, E. Besevegis, N. Giannitsas, and K. Mylonas / Greece -- K. Ueno and I. Nakatani / Japan -- K. Kwak / South Korea -- H.Y. Chen, Y.H. Chen, and J. Zhu / Taiwan -- F.J.R. van de Vijver / Principles of Adaptation of Intelligence Tests to Other Cultures -- F.J.R. van de Vijver, K. Mylonas, V. Pavlopoulos, and J. Georgas / Methodology of Combining the WISC-III Data Sets -- J. Georgas, F.J.R. van de Vijver, L.G. Weiss, and D.H. Saklofske / A Cross-Cultural Analysis of the WISC-III.

Introduction : culture and well-being works by Ed Diener / Ed Diener -- Culture and subjective well-being / William Tov and Ed Diener -- Factors predicting the subjective well-being of nations / Ed Diener, Marissa Diener and Carol Diener -- Cross-cultural correlates of life satisfaction and self-esteem / Ed Diener and Marissa Diener -- Goals, culture and subjective well-being / Shigehiro Oishi and Ed Diener -- Cross-cultural variations in predictors of life satisfaction : perspectives from needs and values / Shigehiro Oishi, Ed Diener, Richard E. Lucas and Eunkook M. Suh -- From culture to priming conditions : self-construal infulences on life satisfaction judgments / Eunkook M. Suh, Ed Diener and John A. Updegraff -- The dynamics of daily events and being well across cultures : when less is more / Shigehiro Oishi, Ed Diener, Dong-Won Choi, Chu Kim-Prieto and Incheol Choi -- Norms for experiencing emotions in different cultures : inter- and intranational differences / Michael Eid and Ed Diener -- Emotions across cultures and methods / Christie Napa Scollon, Ed Diener, Shigehiro Ioshi and Robert Biswas-Diener -- Positivity and the contruction of life satisfaction judgments : global happiness is not the sum of its parts / Ed Diener, Christie Napa Scollon, Shigehiro Oishi, Vivian Dzokoto and Eunkook M. Suh -- Most people are pretty happy, but there is cultural variation : the Inughuit, the Amish and the Maasai / Robert Biswas-Diener, Joar Vittersø and Ed Dierner -- Making the best of a bad situation : satisfaction in the slums of Calcutta / Robert Biswas-Diener and Ed Diener -- Conclusion : what we have learned and where we go next / Ed Diener.

Culture care diversity and universality theory and evolution of the ethnonursing method / Madeleine M. Leininger -- Ethnonursing research method and enablers / Madeleine M. Leininger -- Globalization of transcultural nursing theory and research / Margaret Andrews -- Culture care of the Gadsup Akuna of the eastern highlands of New Guinea: first transcultural nursing study / Madeleine M. Leininger -- Clinical nursing aspects discovered with the culture care theory / Debra A. Curren -- Culture care of German American elders in a nursing home context / Madeleine M.. Mcfarland and Norma Zehnder -- Culture care of the Potawatomi Native Americans who experienced family violence / Linda S. Farrell -- Use of the culture care theory and as a framework for the recruitment, engagement, and retention of culturally diverse nursing students in a traditionally European American baccalaureate nursing program / Marilyn S. McFarland ... [et al.] -- Culture care theory with southern Sudanese of Africa / Madeleine M. Leininger --Selected culture care findings of diverse cultures using culture care theory and ethnomethods / Madeleine M. Leininger -- Generic care of Lebanese Muslim women in the midwestern USA / Hiba Wehbeh-Alamah -- Culture care and health of Russian and Vietnamese refugee communities in the United States / Anna Frances Z. Wenger -- Application of the culture care theory for clinical nurse administrators and managers / Ann O. Hubbert -- Culture care theory and uses in nursing administration / Madeleine M. Leininger -- Synopses of classic research studies on Philippine and U.S. nurses and the culture care of dying patients in hospital and hospice / Madeleine M. Leininger -- Envisioning the future of culture care theory and the ethnonursing method / Madeleine M. Leininger.

Acclimatization, climatology, and the possibility of empire -- Colonial hydrotherapy -- Highland hydrotherapy in Guadeloupe -- The spas of Réunion Island: antechambers to the tropics -- Leisure and power at the spa of Antsirabe, Madagascar -- Korbous, Tunisia: negating the hammam -- Vichy: taking the waters back home.

Includes more than 400 clinical photographs and line drawings and a comprehensive radiology chapter with more than 150 images.--excerpted from p. 4 of cover.

Screening guidelines for sexually transmitted diseases, including HIV infection /Jeffrey D. Klausner --I.Syndromes --Vaginal discharge /Jane Schwebke --Urethral discharge /Jonathan M. Zenilman --Genital ulcer disease /Daniel E. Cohan and Kenneth Mayer --Lower abdominal pain in women /Mark H. Yudin and Harold C. Wiesenfeld --Epididymitis & the acute scrotum syndrome /William M. Geisler and John N. Krieger --Persistent & recurrent urethtitis /Philip M. Grant and Thomas M. Hooton --Pelvic inflammatory disease /Craig R. Cohen --Proctitis & proctocolitis /Anne M. Rompalo --Cervicitis /Jeanne M. Marrazzo --Bacterial vaginosis /Jane R. Schwebke --II.Infections --Chancroid /Stephanie N. Taylor and David H. Martin --Genital chlamydial infections /William M. Eisler and Walter E. Stamm --Genital herpes /Peter Leone --External genital warts /Peter V. Chin-Hong and Joel M. Palefsky --Gonorrhea /Heidi Swygard, Arlene C. Sena, Peter Leone, and Myron S. Cohen --Lymphogranuloma venereum /Christopher S. Hall --Trichomoniasis /Jane R. Schwebke --Syphilis /Michael Augenbraun --Neurosyphilis /Roger P. Simon --III.Special topics --Sexually transmitted diseases in HIV-infected persons /Lisa A. Mills and Thomas C. Quinn --Sexually transmitted diseases in pregnancy /Natali Aziz and Craig R. Cohen --Sexually transmitted diseases in adolescents /Renata Arrington-Sanders, Jeri Dyson, and Jonathan Ellen --Sexually transmitted diseases in men who have sex with men /William Wong --Sexually transmitted diseases in women who have sex with women /Jeanne M. Marrazzo --Principles of serologic testing or syphilis /Edward W. Hook III --Principles of risk reduction counseling /Cornelis A. Rietmeijer --Partner notification & management /Thomas A. Peterman and Richard H. Kahn --Management of abnormal pap smears /Michael E. Hagensee --Commonly encountered genital dermatoses /Laura Hinkle Bachmann --The sexual history /Jeffrey D. Klausner.

Clinical decision making in psychiatry / Barry Nurcombe -- Psychiatric epidemiology / Dan G. Blazer -- Psychiatric genetics / John I. Nurnberger, Jr. & Wade Berrettini -- The psychiatric interview / Barry Nurcombe & Michael H. Ebert -- Diagnostic encounter for children and adolescents / Barry Nurcombe -- Psychological and neuropsychological assessment / James S. Walker, Howard B. Roback, & Larry Welch -- Diagnostic evaluation for children and adolescents / Barry Nurcombe & Michael G. Tramontana -- Developmental psychology / Kenneth A. Dodge -- Psychopharmacologic interventions / Richard C. Shelton -- Behavioral and cognitive-behavioral interventions / Travis Thompson & Steven D. Hollon -- Psychodynamic and social interventions / James I. Nash & James W. Lomax -- Diagnostic formulation, treatment planning, and modes of treatment in children and adolescents / Barry Nurcombe -- Preventive psychiatry / Barry Nurcombe -- Delirium, dementia, and amnestic syndromes / Joseph A. Kwentus & Howard Kirshner -- Substance-related disorders / Richard C. Shelton -- Schizophrenia / Herbert Y. Meltzer ... [et al.] -- Other psychotic disorders / Richard C. Shelton -- Mood disorders / Peter T. Loosen & Richard C. Shelton -- Anxiety disorders / Richard C. Shelton -- Posttraumatic stress disorder and acute stress disorder / Douglas C. Johnson, John H. Krystal, & Steven M. Southwick -- Obsessive-compulsive disorder / William A. Hewlett -- Somatoform disorders / Charles V. Ford -- Factitious disorders and malingering / Charles V. Ford -- Dissociative disorders / Barry Nurcombe -- Sexual dysfunction and paraphilias / Richard Balon & R. Taylor Segraves -- Eating disorders / Harry E. Gwirtsman, James E. Mitchell, & Michael H. Ebert -- Sleep disorders / Camellia P. Clark, Polly J. Moore, & J. Christian Gillin -- Impulse-control disorders / John W. Thompson, Jr. & Daniel K. Winstead -- Adjustment disorders / Ronald M. Salomon & Lucy Salomon -- Personality disorders / David Janowsky -- Intellectual disability / Ludwik S. Szymanski, Sandra L. Friedman, & Elizabeth L. Leonard -- Learning disorders / Michael G. Tramontana -- Motor skills disorder and communication disorders / Michael G. Tramontana & Barry Nurcombe -- Autism and pervasive developmental disorders / Fred R. Volkmar -- Attention-deficit/hyperactivity disorder / Thomas Spencer -- Oppositional defiant disorder and conduct disorder / Barry Nurcombe -- Substance-related disorders in adolescents / Yifrah Kaminer & Deborah R. Simkin -- Depressive disorders in children and adolescents / David A. Brent & Lisa Pan -- Pediatric bipolar disorder / David A. Brent & Raymond J. Pan -- Suicidal behavior in children and adolescents / Robert A. King -- Anxiety disorders in children and adolescents / Barry Nurcombe -- Child maltreatment / William Bernet -- Posttraumatic stress disorder in children and adolescents following a single-event trauma / Brett McDermott -- Tourette disorder and obsessive-compulsive disorder in children and adolescents / Michael H. Bloch & James F. Leckman -- Developmental disorders of attachment, feeding, elimination, and sleeping / Barry Nurcombe -- Gender identity disorder / William Bernet -- Psychological reactions to acute and chronic systemic illness in pediatric patients / Barry Nurcombe -- Emergency psychiatry / Michael J. Sernyak, Jr. & Robert M. Rohrbaugh -- Consultation-liaison psychiatry / Catherine Chiles & Thomas N. Wise -- Forensic psychiatry / William Bernet.

Volume/weight measurement -- Concentration measurement -- Reagent preparation -- Cell culture techniques -- Sample preparation -- Chromatography -- Electrophoresis -- Blotting -- Microscopy -- Enzymatic reactions.

ch. 1. Using biological databases -- ch. 2. Recognizing functional domains -- ch. 3. Finding similarities and inferring homologies -- ch. 4. Finding genes -- ch. 5. Modeling structure from sequence -- ch. 6. Inferring evolutionary relationships -- ch. 7. Analyzing expression patterns -- ch. 8. Analyzing molecular interactions -- ch. 9. Building biological databases -- ch. 10. Comparing large sequence sets -- ch. 11. Assembling sequences -- ch. 12. Analyzing RNA sequences and structures -- ch. 13. Using proteomics techniques -- ch. 14. Cheminformatics -- Appendix 1. User fundamentals -- Appendix 2. Glossary of bioinformatics terms -- Appendix 3. Fundamentals of bioinformatics.

ch. 1. Cell Culture -- ch. 2. Preparation and Isolation of Cells -- ch. 3. Subcellular Fractionation and Isolation of Organelles -- ch. 4. Microscopy -- ch. 5. Characterization of Cellular Proteins -- ch. 6. Electrophoresis and Immunoblotting -- ch. 7. Protein Labeling and Immunoprecipitation -- ch. 8. Cell Cycle Analysis -- ch. 9. Cell Adhesion -- ch. 10. Extracellular Matrix -- ch. 11. In Vitro Reconstitution -- ch. 12. Cell Motility -- ch. 13. Organelle Motility -- ch. 14. Signal Transduction: Protein Phosphorylation -- ch. 15. Protein Trafficking -- ch. 16. Antibodies as Cell Biological Tools -- ch. 17. Macromolecular Interactions in Cells -- ch. 18. Cellular Aging and Death -- ch. 19. Whole Organism and Tissue Analysis -- ch. 20. Expression and Introduction of Macromolecules into Cells -- ch. 21. Fluorescent Protein Technology -- ch. 22. Cell Biology of Chromosomes and Nuclei -- ch. 23. Stem Cells -- ch. 24. Lipids -- ch. 25. Nanotechnology -- ch. 26. Viruses -- ch. 27. RNA-Based Methods in Cell Biology -- Appendix 1. Useful Information and Data -- Appendix 2. Laboratory Stock Solutions and Equipment -- Appendix 3. Commonly Used Techniques -- Appendix. Suppliers.

Current Protocols in Chemical Biology provides validated protocols and overviews about specialized chemical techniques and tools for studies of biology and drug design. These tools include small-molecule design, synthesis, derivatization, handling, and detection as well as advances in laboratory automation, robotics, and medicinal chemistry as applied to high-throughput screening (HTS). Methods for modification of proteins, nucleic acids, carbohydrates and lipids for their use as tools in the study of particular biological systems are also included

Consists of a core publication dated Apr. 1997, and updated by supplements 1 (July 1997)-<57 (July 2010)>. Content is peer-reviewed protocols for flow and image cytometry updated quarterly.

ch. 1. Genetic Mapping -- ch. 2. Genotyping -- ch. 3. Somatic Cell Hybrids -- ch. 4. Cytogenetics -- ch. 5. Strategies for Large-Insert Cloning and Analysis -- ch. 6. Identifying Candidate Genes in Genomic DNA -- ch. 7. Searching Candidate Genes for Mutations -- ch. 8. Clinical Cytogenetics -- ch. 9. Clinical Molecular Genetics -- ch. 10. Cancer Genetics -- ch. 11. Transcriptional Profiling -- ch. 12. Vectors for Gene Therapy -- ch. 13. Delivery Systems for Gene Therapy -- ch. 14. Forensic Genetics -- ch. 15. Model Systems for the Analysis of Human Disease -- ch. 16. Automation and Robotics in Genetic Analysis -- ch. 17. Biochemical Genetics --ch. 18. High-Throughput Sequencing -- ch. 19. Mitochondrial Genetics -- ch. 20. Epigenetics -- Appendix 1. Abbreviations and Useful Data -- Appendix 2. Laboratory Guidelines, Equipment, and Stock Solutions -- Appendix 3. Commonly Used Techniques -- Appendix 4. Chromosome Karyotyping and Idiograms -- Appendix 5. Genetic Linkage Reference Maps: Access to Internet-Based Resources -- Appendix 6. Human-Mouse Comparative Maps -- Appendix. Suppliers.

ch. 1. Care and Handling of Laboratory Animals -- ch. 2. Induction of Immune Responses -- ch. 3. In Vitro Assays for Mouse Lymphocyte Function -- ch. 4. In Vivo Assays for Lymphocyte Function -- ch. 5. Immunofluorescence and Cell Sorting -- ch. 6. Cytokines and Their Cellular Receptors -- ch. 7. Immunologic Studies in Humans -- ch. 8. Isolation and Analysis of Proteins -- ch. 9. Peptides -- ch. 10. Molecular Biology -- ch. 11. Biochemistry of Cell Activation -- ch. 12. Detection and Analysis of HIV -- ch. 13. Complement -- ch. 14. Innate Immunity -- ch. 15. Animal Models for Autoimmune and Inflammatory Disease -- ch. 16. Antigen Processing and Presentation -- ch. 17. Engineering Immune Molecules and Receptors -- ch. 18. Ligand-Receptor Interactions in the Immune System -- ch. 19. Animal Models for Infectious Diseases -- ch. 20. Animal Models for Tumor Immunology -- ch. 21. Microscopy -- ch. 22. Isolation and Differentiation of Stem and Progenitor Cells -- Appendix 1. Abbreviations and Useful Data -- Appendix 2. Commonly Used Reagents and Equipment -- Appendix 3. Commonly Used Immunological Techniques -- Appendix 4. The CD System of Leukocyte Surface Molecules -- Appendix 5. Suppliers.

Emerging technologies -- Microscopy -- Alpha proteobacteria -- Beta proteobacteria -- Enteric gamma proteobacteria -- Nonenteric gamma proteobacteria -- Delta proteobacteria -- Epsilon proteobacteria -- Firmicutes (low G+C gram positive) -- Actinobacteria (high G+C gram positive) -- Chlamydiae -- Spirochetes -- Other eubacteria -- Animal DNA viruses -- Animal RNA viruses -- Plant RNA viruses.

ch. 1. Escherichia coli, Plasmids, and Bacteriophages -- ch. 2. Preparation and Analysis of DNA -- ch. 3. Enzymatic Manipulation of DNA and RNA -- ch. 4. Preparation and Analysis of RNA -- ch. 5. Construction of Recombinant DNA Libraries -- ch. 6. Screening of Recombinant DNA Libraries -- ch. 7. DNA Sequencing -- ch. 8. Mutagenesis of Cloned DNA -- ch. 9. Introduction of DNA into Mammalian Cells -- ch. 10. Analysis of Proteins -- ch. 11. Immunology -- ch. 12. DNA-Protein Interactions -- ch. 13. Yeast -- ch. 14. In Situ Hybridization and Immunohistochemistry -- ch. 15. The Polymerase Chain Reaction -- ch. 16. Protein Expression -- ch. 17. Preparation and Analysis of Glycoconjugates -- ch. 18. Analysis of Protein Phosphorylation -- ch. 19. Informatics for Molecular Biologists -- ch. 20. Analysis of Protein Interactions -- ch. 21. Chromatin Assembly and Analysis -- ch. 22. Nucleic Acid Arrays -- ch. 23. Manipulating the Mouse Genome -- ch. 24. Generation and Use of Combinatorial Libraries -- ch. 25. Discovery and Analysis of Differentially Expressed Genes in Single Cells and Cell Populations -- ch. 26. Gene Silencing -- ch. 27. RNA-Protein Interactions -- ch. 28. Mammalian Cell Culture -- ch. 29. Mouse Phenotyping -- ch. 30. Metabolomics -- Appendix 1. Standard Measurements, Data, and Abbreviations -- Appendix 2. Commonly Used Reagents and Equipment -- Appendix 3. Commonly Used Techniques in Biochemistry and Molecular Biology -- Appendix 4. Suppliers -- Appendix 5. Vectors -- Appendix 6. Pathway Modulators and Inhibitors.

ch. 1. Neuroanatomical Methods -- ch. 2. Imaging -- ch. 3. Cellular and Developmental Neuroscience -- ch. 4. Gene Cloning, Expression, and Mutagenesis -- ch. 5. Molecular Neuroscience -- ch. 6. Neurophysiology -- ch. 7. Neurochemistry/Neuropharmacology -- ch. 8. Behavioral Neuroscience -- ch. 9. Preclinical Models of Neurologic and Psychiatric Disorders -- ch. 10. Human Neuroscience -- Appendix 1. Molecular Biology Techniques -- Appendix 2. Stock Solutions, Equipment, and Laboratory Guidelines -- Appendix 3. Commonly Used Techniques -- Appendix 4. Animal Techniques -- Appendix 5. Databases -- Suppliers.

Includes methods for isolating, maintaining, and differentiating embryonic and adult stem cells.

Development of a conditional mouse model for head and neck squamous cell carcinoma / Bindels, E.M.J., van de Brekel, M.W.M. -- Hypofolatemia as a risk factor for head and neck cancer / Almadori, G. ... [et al.] -- Reduced DNA repair capacity in laryngeal cancer subjects: a comparison of phenotypic and genotypic results / Gajacka, M. ... [et al.] -- Intratumoral genomic heterogeneity in advanced head and neck cancer detected by comparative genomic hybridization / Götte, K. ... [et al.] -- Function and importance of p63 in normal oral mucosa and squamous cell carcinoma of the head and neck / Thurfjell, N. ... [et al.] -- p53, p63 and p73 expression in squamous cell carcinomas of the head and neck and their response to cisplatin exposure / Balz, V. ... [et al.] --Expression of p16 protein is associated with human papillomavirus status in tonsillar carcinomas and has implications on survival / Wittekindt, C. ... [et al.] -- EGFR-antibody-supplemented TPF chemotherapy: preclinical investigations to a novel approach for head and neck cancer induction treatment / Knecht, R. ... [et al.] -- Nuclear factor kappa B as a common target and activator of oncogenes in head and neck squamous cell carcinoma / Chang, A.A., Van Waes, C. -- Antiangiogenic therapy of head and neck squamous cell carcinoma by vascular endothelial growth factor antisense therapy / Riedel, F. ... [et al.] -- Expression pattern of chemokine receptors 6 and 7 in squamous cell carcinoma of the head and neck identifies a novel metastatic phenotype / Wang, J. ... [et al.] -- p53-based immunotherapy of cancer / De Leo, A.B. --p53 as an immunotherapeutic target in head and neck cancer: approaches to reversing unresponsiveness of T lymphocytes and preventing tumor escape / Hoffmann, T.K. ... [et al.] -- Imbalance in absolute counts of T lymphocyte subsets in patients with head and neck cancer and its relation to disease / Kuss, I. ... [et al.] -- Antitumor immunization of head and neck squamous cell carcinoma patients with a virus-modified autologous tumor cell vaccine / Herold-Mende, C. ... [et al.] -- Prognostic factors: confusion caused by bad quality of design, analysis and reporting of many studies / Sauerbrei, W.

Written by expert surgeons and educators, Current Therapy in Oral and Maxillofacial Surgery covers the latest treatment strategies, surgical techniques, and potential complications in OMS. Emphasizing an evidence-based approach, it covers all 12 subspecialties of OMS, addressing topics from surgical principles to oral surgery, anesthesia, cranio-maxillofacial trauma surgery, head and neck surgery, maxillofacial reconstructive surgery, orthognathic surgery, pediatric craniofacial surgery including cleft lip and palate, temporomandibular joint disorders, facial plastic surgery including rhinoplasty and facelifts, obstructive sleep apnea, and oral and maxillofacial infections. At the end of each chapter, Pearls and Pitfalls summarize the authors' insight, recommendations, and experience on that topic. Editor Dr. Shahrokh Bagheri is a noted professor, researcher, and speaker on OMS, and he leads an expert author team including Dr. R. Bryan Bell and Dr. Husain Ali Khan to help you master and apply the latest advances in OMS. More than 1,200 full-color photos and 200 color line drawings illustrate concepts and provide visual guidance in clinical areas. Comprehensive sections and chapters represent essential topics, the newest advances, and controversial topics. Clinical coverage brings together the latest knowledge in OMS in a concise, easy-to-apply way. Resident-specific coverage describes the wide array of subspecialties and treatments available in the armamentarium of the modern OMS. A focus on complications ensures that you are knowledgeable in this important part of any therapy or surgical discipline. Expert contributors include the "best of the best," featuring leading, well-established, and respected surgeons and educators writing on their areas of specialty and providing current treatment strategies.

1. Cross-disciplinary research stirs new challenges into the study of the structure, function, and systems biology of complement / Dimitrios Mastellos and John D. Lambris -- 2. Liver regeneration: a link to inflammation through complement / Robert A. DeAngelis, Maciej M. Markeiwski, and John D. Lambris -- 3. The Role of third complement component (C3) in homing of hematopoietic stem/progenitor cells into bone marrow / Ryan Reca ... [et al.] -- 4. Complement system and the eye / Purushottam Jha ... [et al.] -- 5. To regeneration ... with complement / Panagiotis A. Tsonis, John D. Lambris, and Katia Del Rio-Tsonis -- 6. Self, non-self and danger: a complementary view / Jörg Köhl -- 7. gClqR/p33 serves as a molecular bridge between the complement and contact activation systems and is an important catalyst in inflammation / Berhane Ghebrehiwet ... [et al.] -- 8. Possible immunoprotective and angiogenesis-promoting roles for malignant cell-derived prostasomes: a new paradigm for prostatic cancer? / Kristina Nilsson Ekdahl ... [et al.] -- 9. Diversified components of the bony fish complement system: more genes for robuster innate defense? / Miki Nakao ... [et al.] -- 10. C5b-9 complement complex in autoimmune demyelination: dual role in neuroinflammation and neuroprotection / Horea Rus, Cornelia Cudrici, and Florin Niculescu -- 11. The Double-edged flower: roles of complement protein C1q in neurodegenerative diseases / Andrea J. Tenner and Maria I. Fonseca -- 12. The Role of the complement system in the pathogenesis of experimental autoimmune encephalomyelitis and multiple sclerosis / Nóra Terényi, József Prechl, and Anna Erdei -- 13. The Complement system: a potential target for stroke therapy / J. Mocco ... [et al.] -- 14. Observations on complement activity in the two-stage inflammatory/hemostatic response in the baboon and human models of E. coli sepsis and endotoxemia / Fletcher B. Taylor, Jr., Eric Hack, and Florea Lupu -- 15. Complement activation during sepsis in humans / Heike Schreiber ... [et al.] -- 16. Three distinct profiles of serum complement C4 proteins in pediatric systemic lupus erythematosus (SLE) patients: tight associations of complement C4 and C3 protein levels in SLE but not in healthy subjects / Yee-Ling Wu ... [et al.] -- 17. A Minimum CR2 binding domain of C3d enhances immunity following vaccination / Joseph F. Bower and Ted M. Ross -- 18. Structure and function of ficolins / Yuichi Endo, Yu Liu, and Teizo Fujita -- 19. Role of mannose-binding lectin (MBL2) genotyping in predicting the risk of recurrent otitis media (rOM) / Lieve Nuytinck ... [et al.] -- 20. Conformational complexity of complement component C3 / Bert J.C. Janssen and Piet Gros -- 21. Disease-associated sequence variations in factor H: a stuctural biology approach / Andrew P. Herbert ... [et al.] -- 22. Transdermal pharmacology of small molecule cyclic C5a antagonists / Lavinia M. Proctor ... [et al.] -- 23. Inactivation of complement by recombinant human C3 derivatives / Edzard Spillner, Johanna Kölln, and Reinhard Bredehorst -- 24. Complement analysis in clinic and research / Tom E. Mollnes and Michael Kirschfink -- 25. Cell-bound complement activation products (CB-CAPs) as a source of lupus biomarkers / Sarah J. Calano ... [et al.].

Pentraxins in Humoral Innate Immunity / Antonio Inforzato, Barbara Bottazzi, Cecilia Garlanda, Sonia Valentino and Alberto Mantovani -- Galectins as Pattern Recognition Receptors: Structure, Function, and Evolution / Gerardo R. Vasta -- The Role of Innate Immunity in Trafficking of Hematopoietic Stem Cells - An Emerging Link Between Activation of Complement Cascade and Chemotactic Gradients of Bioactive Sphingolipids / Mariusz Z. Ratajczak, ChiHwa Kim, Wan Wu, Dong Myung Shin and Ewa Bryndza, et al. -- Interaction of the Microbiome with the Innate Immune Response in Chronic Wounds / Elizabeth A. Grice and Julia A. Segre -- Pathogenic Microbes and Community Service Through Manipulation of Innate Immunity / George Hajishengallis, Jennifer L. Krauss, Shuang Liang, Megan L. McIntosh and John D. Lambris -- A Conserved Host and Pathogen Recognition Site on Immunoglobulins: Structural and Functional Aspects / Bruce D. Wines, Halina M. Trist, William Farrugia, Chloe Ngo and John Trowsdale, et al. -- Advances in Understanding the Structure, Function, and Mechanism of the SCIN and Efb Families of Staphylococcal Immune Evasion Proteins / Brandon L. Garcia, Kasra X. Ramyar, Daniel Ricklin, John D. Lambris and Brian V. Geisbrecht -- Granzyme B: A New Crossroad of Complement and Apoptosis / Mario Perl, Stephanie Denk, Miriam Kalbitz and Markus Huber-Lang -- Role of C3, C5 and Anaphylatoxin Receptors in Acute Lung Injury and in Sepsis / Markus Bosmann and Peter A. Ward --Complement Involvement in Neovascular Ocular Diseases / Ryoji Yanai, Aristomenis Thanos and Kip M. Connor -- Platelets, Complement, and Contact Activation: Partners in Inflammation and Thrombosis / Osama A. Hamad, Jennie Bäck, Per H. Nilsson, Bo Nilsson and Kristina N. Ekdahl -- Nuclear Factor-κB in Immunity and Inflammation: The Treg and Th17 Connection / Qingguo Ruan and Youhai H. Chen -- Function of Act1 in IL-17 Family Signaling and Autoimmunity / Ling Wu, Jarod Zepp and Xiaoxia Li -- Differential Effect of Inhibiting MD-2 and CD14 on LPS- Versus Whole E. coli Bacteria-Induced Cytokine Responses in Human Blood / D. Christiansen, O. L. Brekke, J. Stenvik, J. D. Lambris and T. Espevik, et al. -- Zebrafish: Model for the Study of Inflammation and the Innate Immune Response to Infectious Diseases / Beatriz Novoa and Antonio Figueras -- Monocyte-derived Inflammatory Dendritic Cells in the Granuloma During Mycobacterial Infection / Heidi A. Schreiber and Matyas Sandor -- NK/DC Crosstalk in Anti-viral Response / Emanuela Marcenaro, Simona Carlomagno, Silvia Pesce, Alessandro Moretta and Simona Sivori -- Innate-Adaptive Crosstalk: How Dendritic Cells Shape Immune Responses in the CNS / Benjamin D Clarkson, Erika Héninger, Melissa G Harris, JangEun Lee and Matyas Sandor, et al. -- Nutritional Immunity: Homology Modeling of Nramp Metal Import / Mathieu F. M. Cellier.

Cushing's Disease: An Historical Perspective -- Molecular Biology of Cushing's Disease -- Pathology of Cushing's Disease -- The Diagnosis of Cushing's Syndrome -- Pseudo-Cushing's Syndrome -- Cyclic Cushing's Disease -- Differential Diagnosis of Cushing's Syndrome -- Radiologic Imaging Techniques in Cushing's Disease -- Surgical Treatment of Cushing's Disease -- Postoperative Management and Assessment of Cure -- Radiation Therapy in the Management of Cushing's Disease -- Medical Management of Cushing's Disease -- Recurrent Cushing's Disease -- Diagnosis and Treatment of Pediatric Cushing's Disease -- Silent Corticotroph Adenomas -- Cushing's Syndrome in Pregnancy -- Nelson's Syndrome: Corticotroph Tumor Progression After Bilateral Adrenalectomy in Cushing's Disease -- Psychosocial Aspects of Cushing's Disease.

v. 2 Unusual cases.

Overview -- Occurance workgroup -- Causes, prevention, and mitigation workgroup -- Toxins workgroup -- Analytical methods workgroup -- Human health effects workgroup -- Ecosystem effects workgroup -- Risk assessment workgroup.

Part I. In vitro protocols for studying expression and activity of cyclooxygenase enzymes and characterisation of their inhibition patterns -- 1. In vitro cyclo-oxygenase expression and activity protocols : introduction to Part I / Roderick J. Flower -- 2. Techniques used to study regulation of cyclooxygenase-2 promoter sites / Hiroyasu Inoue and Rieko Nakata -- 3. Purification of recombinant human COX-1 and COX-2 / James K. Gierse -- 4. Cloning and expression of cyclooxygenase-1 and cyclooxygenase-2 / Nicholas R. Staten and Beverly A. Reitz -- 5. Expression of cyclooxygenase isoforms in the baculovirus expression system / John C. Hunter, Natalie M. Myres, and Daniel L. Simmons -- 6. Peroxidase active site activity assay / Kelsey C. Duggan, Joel Musee, and Lawrence J. Marnett -- 7. Study of inhibitors of the PGH synthases for which potency Is regulated by the redox state of the enzymes / Olivier Boutaud and John A. Oates -- 8. Different methods for testing potential cyclooxygenase-1 and cyclooxygenase-2 inhibitors / Stefan Laufer and Sabine Luik -- 9. In vitro cyclooxygenase activity assay in tissue homogenates / Samir S. Ayoub -- 10. Techniques used to characterize the binding of cyclooxygenase Inhibitors to the cyclooxygenase active site / William F. Hood -- 11. In vitro Assays for cyclooxygenase activity and inhibitor characterization / Mark C. Walker and James K. Gierse -- -- Part II. Extraction and measurement of prostanoids and isoprostanes -- 12. Extraction and measurement of prostanoids and isoprostanes : introduction to Part II / Paola Patrignani -- 13. Prostanoid extraction and measurement / Lorenzo Polenzani and Samir S. Ayoub -- 14. Measurement of 8-iso-prostaglandin F2a in biological fluids as a measure of lipid peroxidation / Stefania Tacconelli, Marta L. Capone, and Paola Patrignani -- -- Part III. In vivo models to study involvement of cyclooxygenase products in health and disease -- 15. In vivo models to study cyclooxygenase products in health and disease: introduction to Part III / Derek W. Gilroy, Melanie Stables, and Justine Newson -- 16. Protocols to assess the gastrointestinal side effects resulting from inhibition of Cyclo-Oxygenase isoforms / Brendan J.R. Whittle -- 17. Cyclooxygenase enzymes and their products in the carrageenan-induced pleurisy in rats / Adrian R. Moore, Samir S. Ayoub, and Michael P. Seed -- 18. Iloprost-induced nociception : determination of the site of anti-nociceptive action of cyclooxygenase inhibitors and the Involvement of cyclooxygenase products in central mechanisms of nociception / Samir S. Ayoub and Regina M. Botting.

"Cysteine proteases expressed by pathogenic organisms play key roles in virulence including host entry, feeding and suppression of host immune responses. This book gives comprehensive coverage to all aspects of pathogen cysteine proteases and brings together numerous scientific advances which have been made over many years. Thus, the biochemistry, molecular biology and structure function relationships of these important pathogen enzymes are covered in detail. Written by leading researchers from Europe, Australia and North America, this book is essential reading for students and professionals interested in human medicine and infectious disease research"--Provided by publisher.

The CFTR gene: structure, mutations and specific therapeutic approaches / Nissim-Rafinia, M., Linde, L., Kerem, B. -- Exquisite and multilevel regulation of CFTR expression / Trezise, A.E.O. -- Intracellular processing of CFTR / Barriere, H., Lukacs, G.L. -- Structure of the cystic fibrosis transmembrane conductance regulator / Stratford, F.L.L., Bear, C.E. -- Function of CFTR protein: ion transport / Chen, J.-H. ... [et al.] -- Cystic fibrosis. Function of CFTR Protein: regulatory functions / Coakley, R.D., Stutts, M.J. -- Function of CFTR protein: developmental role / Gill, D., Larson, J.E. -- Genotype-phenotype correlations in cystic fibrosis / Dorfman, R., Zielenski, J. -- Diagnosis of cystic fibrosis, CFTR-related disease and screening / Karczeski, B.A., Cutting, G.R. -- CF modifier genes / Griesenbach, U., Alton, E.W.F.W., Davies, J.C. -- Animal models / Dorin, J.R -- In vitro/ex vivo fluorescence assays of CFTR chloride channel function / Verkman, A.S., Galietta, L.J.V. -- In vivo measurement of airway potential difference to assess CFTR function in man / Middleton, P., Alton, E.W.F.W. -- Arrays and proteomics / Ogilvie, V.C., MacGregor, G. -- Pathogenesis of pulmonary disease in cystic fibrosis / Mall, M., Boucher, R.C. -- Infection versus inflammation / Ziady, A.G., Davis, P.B. -- Pseudomonas aeruginosa: clinical research / Armstrong, D. -- Pseudomonas aeruginosa: basic research / Scott, F.W., Pitt, T.L. -- Other gram-negative organisms: Burkholderia cepacia complex and Stenotrophomonas maltophilia / Govan, J.R.W. -- Staphylococcus aureus and MRSA / Conway, S., Denton, M. -- Nontuberculous mycobacterial lung disease in patients with cystic fibrosis / Griffith, D.E -- Respiratory fungal infections and allergic bronchopulmonary aspergillosis / Que, C., Geddes, D. -- Advanced disease management and advances in transplant medicine / Carby, M.R., Hodson, M.E. -- Current and novel antimicrobial approaches / Davies, J.C. -- Anti-inflammatory agents: a clinical perspective / Hilliard, T.N., Balfour-Lynn, I.M. -- Recent advances in infant and pre-school lung function / Ranganathan, S. -- Recent advances in imaging / Oikonomou, A., Hansell, D.M. -- New pharmacological approaches for treatment of cystic fibrosis / Rubenstein, R.C. -- Gene and stem cell therapy / Boyd, A.C. -- Gut disease: clinical manifestations, pathophysiology, current and new treatments / Taylor, C.J., Hardcastle, J. -- Pancreatic involvement: clinical manifestations, pathophysiology and new treatments / Lindley, K.J. -- Cystic fibrosis: liver disease / Westaby, D. -- Fertility, contraception, incontinence and pregnancy / Thorpe-Beeston, J.G. -- Arthritis, vasculitis and bone disease / Elkin, S. -- Diabetes in cystic fibrosis / Bridges, N., Spowart, K. -- Challenges for nurses / Madge, S. -- Dietetics / Wolfe, S., Morton, A. -- Physiotherapy / Pryor, J.A. ... [et al.] -- Psychological interventions / Bryon, M. -- The future / Bush, A. ... [et al.].

History of cystic fibrosis / James M. Littlewood -- Epidemiology of cystic fibrosis / Sarah Walters and Anil Mehta -- Molecular biology of cystic fibrosis : CFTR processing and functions, and classes of mutations / Malka Nissim-Rafinia, Batsheva Kerem, and Eitan Kerem -- Pathophysiology : epithelial cell biology and ion channel function in the lung, sweat gland, and pancreas / Raymond D. Coakley and Richard C. Boucher -- Immunology of cystic fibrosis / Gerd Döring and Felix Ratjen -- Genotype-phenotype correlations and modifier genes / Jane C. Davies -- Variability of clinical course in cystic fibrosis / Michael Schechter -- Diagnosis of cystic fibrosis / Colin Wallis -- The challenge of screening newborn infants for cystic fibrosis / Kevin W. Southern -- How to manage the screened patient / Philip Robinson -- Microbiology of cystic fibrosis : role of the clinical microbiology laboratory, susceptibility and synergy studies, and infection control / Samiya Razvi and Lisa Saiman -- Respiratory disease : infection / Ian M. Balfour-Lynn and J. Stuart Elborn -- Respiratory disease : non-infectious complications / Margaret Hodson and Andrew Bush -- Sleep, lung mechanics, and work of breathing, including NIPPV / Brigitte Fauroux and Annick Clément -- Delivery of therapy to the cystic fibrosis lung / Harm A.W.M. Tiddens and Sunalene G. Devadason -- The upper airway in cystic fibrosis / William E. Grant -- Gastrointestinal disease in cystic fibrosis / Ian Gooding and David Westaby -- Liver, biliary, and pancreatic disease / Vicky Dondos and David Westaby -- Insulin deficiency and diabetes related to cystic fibrosis / Christopher D. Sheldon and Lee Dobson -- Growth and puberty / Nicola Bridges -- Cystic-fibrosis-related low bone mineral density / Sarah L. Elkin and Charles S. Haworth -- Other system disorders in cystic fibrosis / Khin Ma Gyi -- Sexual and reproductive health / Susan M. Sawyer -- Transplantation / Paul Aurora, Khin Gyi, and Martin Carby -- Using databases to improve care / Sheila G. McKenzie and Margaret E. Hodson -- Infant and pre-school children : lung function / Sarath Ranganathan -- Infant and pre-school children : role of bronchoscopy / Gary Connett -- Infant and pre-school children : imaging the lungs / Samatha Sonnappa and Catherine M. Owens -- Physiological monitoring of older children and adults / Mark Rosenthal -- Exercise : testing / David M. Orenstein and Wolfgang Gruber -- Exercise : use in therapy / David M. Orenstein and Linda W. Higgins -- Clinical outcome measures to assess new treatments for CF lung disease / Jane C. Davies and Eric W.F.W. Alton on behalf of the UKCF Gene Therapy Consortium -- Cystic fibrosis center care / Penny Agent and Susan Madge -- Nursing care / Susan Madge and Christine Hockings -- Physiotherapy / Craig Lapin, Anne Lapin, and Jennifer A. Pryor -- Nutritional aspects / Sue Wolfe and Sarah Collins -- Psychological aspects of cystic fibrosis / Alistair J.A. Duff and Helen Oxley -- Palliative care in cystic fibrosis / Catherine E. Urch and Margaret E. Hodson -- Gene and stem cell therapy / Uta Griesenbach and Eric W.F.W. Alton on behalf of the UKCF Gene Therapy Consortium -- Non-gene therapy treatments : what will they deliver? / Adam Jaffé and Pierre Barker -- The future : how will management change? / Andrew Bush and Duncan Geddes -- Transition form / Susan Madge and Jacqueline Francis -- Practical nursing care required by the cystic fibrosis patient and its delivery / Frances Duncan-Skingle and Tracey Catling.

Cytochrome P450 nomenclature, 2004 / David R. Nelson -- Spectral analyses of cytochromes P450 / John B. Schenkman and Ingela Jansson -- Establishment of functional human cytochrome P450 monooxygenase systems in Escherichia coli / Michael P. Pritchard, Lesley McLaughlin, and Thomas Friedberg -- Purification of cytochromes P450: products of bacterial recombinant expression systems / F. Peter Guengerich and Martha V. Martin -- Expression of recombinant flavin-containing monooxygenases in a baculovirus/insect cell system / Azara Janmohamed ... [et al.] -- Cytochrome P450 reconstitution systems / Hiroshi Yamazaki and Tsutomu Shimada -- Catalytic assays for human cytochrome P450: an introduction / Thomas K.H. Chang and David J. Waxman -- Enzymatic analysis of cDNA-expressed human CYP1A1, CYP1A2, and CYP1B1 with 7-ethoxyresorufin as substrate / Thomas K.H. Chang and David J. Waxman -- Spectrofluorometric analysis of CYP2A6-catalyzed coumarin 7-hydroxylation / David J. Waxman and Thomas K.H. Chang -- Determination of CYP2B6 component of 7-ethoxy-4-trifluoromethylcoumarin O-deethylation activity in human liver microsomes / Thomas K.H. Chang, Charles L. Crespi, and David J. Waxman -- High-performance liquid chromatography analysis of CYP2C8-catalyzed paclitaxel 6[alpha]-hydroxylation / Charles L. Crespi, Thomas K.H. Chang, and David J. Waxman -- Determination of CYP2C0-catalyzed diclofenac 4'-hydroxylation by high-performance liquid chromatography / Charles L. Crespi, Thomas K.H. Chang, and David J. Waxman -- CYP2C19-mediated (S)-mephenytoin 4'-hydroxylation assayed by high-performance liquid chromatography with radiometric detection / Charles L. Crespi, Thomas K.H. Chang, and David J. Waxman -- CYP2D6-dependent bufuralol 1'-hydroxylation assayed by reverse-phase ion-pair high-performance liquid chromatography with fluorescence detection / Charles L. Crespi, Thomas K.H. Chang, and David J. Waxman -- Spectrophotometric analysis of human CYP2E1-catalyzed p-nitrophenol hydroxylation / Charles L. Crespi, Thomas K.H. Chang, and David J. Waxman -- Thin-layer chromotography analysis of human CYP23A-catalyzed testosterone 6[beta]-hydroxylation / David J. Waxman and Thomas K.H. Chang -- Determination of CYP4A11-catalyzed lauric acid 12-hydroxylation by high-performance liquid chromotography with radiometric detection / Charles L. Crespi, Thomas K.H. Chang, and David J. Waxman -- An isocratic high-performance liquid chromatography assay for CYP7A1-catalyzed cholesterol 7[alpha]-hydroxylation / David Waxman and Thomas K.H. Chang -- Use of 7-ethoxycoumarin to monitor multiple enzymes in the human CYP1, CYP2, and CYP3 families / David J. Waxman and Thomas K.H. Chang -- Benzydamine N-oxygenation as a measure of flavin-containing monooxygenase activity / Catherine K. Yeung and Allan E. Rettie -- Prochiral sulfoxidation as a probe for flavin-containing monooxygenases / Catherine K. Yeung and Allan E. Rettie -- Targeting antipeptide antibodies toward cytochrome P450 enzymes / Robert J. Edwards -- The Human Cytochrome P450 Allele Nomenclature Committee web site: submission criteria, procedures, and objectives / Sarah C. Sim and Magnus Ingelman-Sundberg -- Genotyping for cytochrome P450 polymorphisms / Ann K. Daly, Barry P. King, and Julian B.S. Leathart -- Hepatocyte cultures in drug metabolism and toxicological research and testing / Tamara VanHaecke and Vera Rogiers -- Isolation of rat hepatocytes / Peggy Papeleu ... [et al.] -- Rat hepatocyte cultures: conventional monolayer and cocultures with rat liver epithelial cells / Tom Henkens ... [et al.] -- Rat hepatocyte cultures: collagen gel sandwich and immobilization cultures / Mathieu Vinken ... [et al.] -- Hepatocytes in suspension / Greetje Elaut ... [et al.] -- Isolation of rat bone marrow stem cells / Sarah Snykers, Tamara Vanhaecke, and Vera Rogiers -- Transfection of primary cultures of rat hepatocytes / Mina Edwards -- Human hepatocyte culture / Lydiane Pichard ... [et al.] -- Determination of cellular localization of the expression of flavin-containing monooxygenase genes in mouse tissues by in situ hybridization / Azara Janmohamed, Ian R. Phillips, and Elizabeth A. Shephard -- Deletion of genes from the mouse genome using cre/loxP technology / Diana Hernandez ... [et al.] -- Characterization of targeted mouse embryonic stem cell chromosomes: karyotyping and fluorescence in situ hybridization of metaphase spreads / Diana Hernandez, Ian R. Phillips, and Elizabeth A. Shephard -- Microinjection of targeted embryonic stem cells and establishment of knockout mouse lines for fmo genes / Diana Hernandez ... [et al.] -- Use of reporter genes to measure xenobiotic-mediated activation of CYP gene transcription / Nick Plant.

The biology of cytokines : general principles, properties and lessons from animal models / Davide Agnello and Massimo Gadina -- Genetics of multifactorial disorders / Jorge R. Oksenberg and John D. Rioux -- Statistical approaches to analysis of polymorphisms in multifactorial disorders / An Goris and Mariza de Andrade -- Introduction to integrated bioinformatic resources for cytokine genetics research / Ross Lazarus -- Cytokine gene nucleotide sequence alignments / Jeffrey Bidwell -- SNP genotyping techniques / Pui-Yan Kwok -- The IL1 cluster / Tanja Pessi ... [et al.] -- IL-2 biology and polymorphisms in multifactorial conditions / Fuencisla Matesanz, María Fedetz, and Antonio Alcina -- The chromosome 5q23.1-q 31.1 cluster of cytokines / Tarja Laitinen -- IL10 / Ross Lazarus --; The IL19 subfamily of cytokines / Sulev Kõks ... [et al.] -- The IFNG-IL26-IL22 cytokine gene cluster / Koen Vandenbroeck and An Goris -- TNF polymorphisms and disease / Reginald M. Gorczynski and Ivo Boudakov -- Macrophage migration inhibitory factor (MIF) / Zaynab Alourfi, David W. Ray, and Rachelle Donn -- Polymorphisms of chemokines and their receptors / Bénédicte Puissant, Christophe Combadière, and Elise Lavergne -- Asthma and atopy / Jussi Karjalainen ... [et al.] -- Common rheumatic diseases / Rachael Kilding and Anthony G. Wilson -- Systemic lupus erythematosus / Sandra D'Alfonso -- Sjögren's syndrome / Marja Pertovaara -- Multiple sclerosis / Orhun H. Kantarci and Brian G. Weinshenker --; Type 1 and 2 diabetes / Regine Bergholdt and Flemming Pociot -- Psoriasis / Sulev Kõks ... [et al.] -- Diseases of the gastrointestinal tract / Thomas Höhler -- Pulmonary fibrosis / Berran Yucesoy and Michael I. Luster -- Atherosclerosis / Giuseppina Candore ... [et al.] -- Longevity / Irene Maeve Rea ... [et al.] -- AIDS / Alexandre Vasilescu, Hervé Do, and Jean-Francois Zagury -- Tropical infectious diseases / Thereza Quirico-Santos ... [et al.] -- Suseptibility to infection and severe disease in schistosomiasis / Violaine Arnaud and Christophe Chevillard.

Introduction to cytokines as targets for immunomodulation / Theresa L. Whiteside -- Cytokine measurement tools for immunotoxicology / Rob J. Vandebriel -- The relevance of the T1/T2 paradigm in immunotoxicology: example of drug hypersensitivity reactions / Hervé Lebrec and John Vasilakos -- Microbial exploitation and subversion of the human chemokine network / James E. Pease -- The use of cytokines in the identification and characterization of chemical allergens / Rebecca J. Dearman and Ian Kimber -- Inflammatory cytokines and lung toxicity / Debra L. Laskin ... [et al.] -- Cytokine polymorphisms and relationship to disease / Berran Yucesoy ... [et al.] -- Effects of drugs of abuse on cytokine responses / Stephen B. Pruett -- Preclinical approaches for safety assessment of cytokines / Peter T. Thomas and Melissa S. Beck-Westermeyer -- Flu-like syndrome and cytokines / Jacques Descotes and Thierry Vial -- Cytokine-induced vascular leak syndrome / Roxana G. Baluna -- Cytokines and autoimmune diseases: from the control of autoimmune diseases with anti-cytokine treatment to the induction of autoimmunity with cytokine treatment / Pierre Miossec -- Evaluation of antibodies in clinical trials of cytokines / Steven Swanson -- Cytokines and pharmacokinetic drug interactions / Kenneth W. Renton -- Evaluation of the immunological effects of cytokines administered to patients with cancer / Michael J. Robertson -- Clinical adverse effects of cytokines on the immune system / Thierry Vial and Jacques Descotes.

Helicobacter pylori and cytokines in the genesis of gastric cancer / Richard M. Peek, Jr. -- HTLV-1, cytokines, and cancer / Michael Lairmore and Lee Ratner -- Herpesviruses, cytokines, and cancer / Frank J. Jenkins and Heather R. Hensler -- Tumor necrosis factor and cancer / Mark DeWitte ... [et al.] -- Transforming growth factor-[beta] and cancer / Alyssa R. Bonine-Summers, Brian K. Law, and Harold L. Moses -- Interleukin-1 family of cytokines and cancer / Michael T. Lotze--Interleukin-4/13 and cancer / Koji Kawakami and Raj K. Puri -- Interleukin-6 and Castleman's disease / Norihiro Nishimoto -- Interleukin-10 (IL-10): biology, immune, regulation, and cancer / Shin-ichiro Fujii and Michael T. Lotze -- Cytokines in multiple myeloma: therapeutic implications / Dharminder Chauhan, Teru Hideshima, and Kenneth C. Anderson -- In vivo murine cytokine models and the genesis of cancer / Todd A. Fehniger, Megan A. Cooper, Michael A. Caligiuri --Experimental models of cytokines and cancer prevention / Mark J. Smyth ... [et al.] -- Cytokines in the tumor stroma / Michael C. Ostrowski -- Cytokines and tumor angiogenesis / Sharmila Roy-Chowdhury and Charles K. Brown -- Chemokine and receptor expression in tumor progression / Paola Allavena, Federica Marchesi, and Alberto Mantovani -- The biology of cancer cachexia and the role of TNF-[alpha] / Denis C. Guttridge -- Interleukin-2 and cancer therapy / Kim Margolin and Joseph Clark -- Interleukin-12 and cancer therapy / Timothy E. Bael and Jared Gollob -- The type I interferon system with emphasis on its role in malignancies: interferons are more than "antivirals" / Stergios J. Moschos ... [et al.] -- Combination cytokine therapy / Seth M. Cohen and Howard L. Kaufman -- Novel strategies for cytokine administration via targetting / Paul M. Sondel ... [et al.] -- Cytokines and cancer vaccines / Hideho Okada and Michael T. Lotze -- Anticytokine therapy / Miguel A. Villalona-Calero -- Cytokines in the supportive care of cancer / John A. Glaspy.

1. Behavioral Effects of Cytokines: A Psychiatrist's Perspective / Ziad Kronfol -- 2. Worried to Death? Stress, Worry, and Immune Dysregulation in Health and HIV -- 3. Psychological Stress and Its Relationship to Cytokines and Inflammatory Diseases / Rama Murali, Margaret D. Hanson, and Edith Chen -- 4. Role of Cytokines in Depression / Ghanshyam N. Pandey and Yogesh Dwivedi -- 5. Loneliness, Dysphoria, Stress, and Immunity: A Role for Cytokines / Louise C. Hawkley, Jos A. Bosch, Christopher G. Engeland, Phillip T. Marucha, and John T. Cacioppo -- 6. Stress, Cytokines, and Peripheral Analgesia / Peter John Cabot -- 7. Alexithymia, Stress, and Immunity / Olivier Guilbaud, Maurice Corcos, and Philippe Jeammet -- 8. Roles of Mu-Opioid Receptor and Endogenous Opiates in Stress-Induced Immunosuppression / Jennifer Kelschenbach, Horace H. Loh, and Sabita Roy -- 9. Stress, Opioid Peptides, and Immune Reponse / Javier Puente, Marion E. Wolf, M. Antonieta Valenzuela, and Aron D. Mosnaim -- 10. Met-Enkephalin in Oxidative Stress / Tihomir Balog, Sandra Soboc̆anec, Vis̆nja S̆verko, Helena Haberstock-Debić, and Tatjana Marotti -- 11. Chronic Stress Induces Death of Lymphocytes / Erwei Sun, Lixin Wei, Arthur I. Roberts, Catherine Liu, and Yufang Shi -- 12. Interleukin-10 and the Hypothalamic--Pituitary--Adrenal Axis / Eric M. Smith, Huolin Tu, and Thomas K. Hughes, Jr. -- 13. Cytokines, Stress, and Depression / Adrian J. Dunn -- 14. Immunoconversion in Acute Phase Response / Istvan Berczi, Andres Quintanar-Stephano, and Kalman Kovacs -- 15. Interferon in Health and Disease / Nachum Dafny, Pamela B. Yang, and Stanley A. Brod -- 16. Neuropeptide Precursor Processing in Immunocytes: Involvement in Neuroimmune Communication / Robert Day and Michel Salzet -- 17.Clinical Relevance of Opioid-Induced Immunosuppression: Are All Drugs Similar? / Paola Sacerdote, Sivia Franchi, and Cataldo Martucci -- 18. Human Retroviruses and the Cytokine Network / Massimo Alfano and Guido Poli -- 19. Psychiatric Toxicity of Interferon: A Model for Understanding the Etiology of Major Depression and Chronic Fatigue Syndrome? -- 20. Role of Genetic Predisposition, Cytokines, and Neuroendocrine Response in Development of Thyroid Autoimmunity / Antonio Martocchia and Paolo Falaschi -- 21. Gender Differences, Stress, and Immunity / Nicholas P. Plotnikoff and Robert E. Faith.

Cervical and vaginal cytology / Edmund S. Cibas -- Respiratory tract / Christopher A. French -- Urine and bladder washings / Andrew A. Renshaw -- Pleural, pericardial, and peritoneal fluids / Edmund S. Cibas -- Peritoneal washings / Edmund S. Cibas -- Cerebrospinal fluid / Edmund S. Cibas -- Gastrointestinal tract / David W. Kindelberger and Helen H. Wang -- Breast / Barbara S. Ducatman and Helen H. Wang -- Thyroid / Edmund S. Cibas -- Salivary gland / Jeffrey F. Krane and William C. Faquin -- Lymph nodes / Paul E. Wakely, Jr., and Edmund S. Cibas -- Liver / Barbara S. Ducatman -- Pancreas and biliary tree / Jian Shen and David W. Kindelberger -- Kidney and adrenal gland / Andrew A. Renshaw and Edmund S. Cibas -- Ovary / Edmund S. Cibas -- Soft tissue / Xiaohua Qian -- Laboratory management / Edmund S. Cibas.

Part 1.Basics of the Cytoskeleton --ACTIN /Vera Dugina, Richard Arnoldi, Paul A. Janmey and Christine Chaponnier --Microtubules /Pavel Dráber and Eduarda Dráberová --The Kinesin Superfamily /Linda Wordeman --Basics of the Cytoskeleton: Myosins /Omar A. Quintero, Judy E. Moore and Christopher M. Yengo --Part 2.Actin and Disease --The Actin Cytoskeleton and Membrane Organisation in T Lymphocytes /Rhea Cornely, Thomas Grewal and Katharina Gaus --Thin Filament Diseases of Striated Muscle /Anthony J. Kee and Edna C. Hardeman --Filamins and Disease /Stephen P. Robertson and Philip B. Daniel --LIM Kinase and Cancer Metastasis /Alice Schofield and Ora Bernard --Actin Mutations and Deafness /Matías Morín, Fernando Mayo, Felipe Moreno and Miguel A. Moreno-Pelayo --Therapeutic Targeting of the Actin Cytoskeleton in Cancer /Teresa Bonello, Jason Coombes, Galina Schevzov, Peter Gunning and Justine Stehn.Part 3.Microtubules and Disease --Microtubules as a Target in Cancer Therapy /April L. Risinger and Susan L. Mooberry --Microtubules, Drug Resistance, and Tumorigenesis /Joshua A. McCarroll and Maria Kavallaris --Posttranslational Modifications of Tubulin /Suzan K. Chao, Chia-Ping H. Yang and Susan Band Horwitz --Stathmin and Cancer /Dominic Chi Hiung Ng and Frances Byrne --The Biology and Pathobiology of Tau Protein /Garth F. Hall --Tubulin-Related Malformations of Cortical Development /Xavier H. Jaglin, Jamel Chelly and Nadia Bahi-Buisson --Part 4.Intermediate Filaments and Disease --Spectrins in Human Diseases /Marie-Christine Lecomte --Laminopathies /Nadir M. Maraldi and Giovanna Lattanzi --Desmin and Heart Disease /J. Scott Pattison and Jeffrey Robbins --Neurodegenerative Diseases and Intermediate Filaments /Rodolphe Perrot and Jean-Pierre Julien.

Central axonal development and pathology in early life / Robin L. Haynes and Hannah C. Kinney -- Microtubules in the nervous system / Nobuyuki Fukushima -- Tau phosphorylation / Jesús Avila and Félix Hernández -- Tau pathology / Nicolas Sergeant and Luc Buée -- Tauopathy and brain aging / Akihiko Takashima -- Microtubule-associated protein 4 / Kiyotaka Tokuraku ... [et al.] -- Structure of neural intermediate filaments / David A.D. Parry -- Alpha-internexin: the fourth subunit of neurofilaments in the mature CNS / Aidong Yuan and Ralph A. Nixon -- Peripherin pathology / Jesse R. McLean and Janice Robertson -- Neurofilament cross-bridge: a structure associated specifically with the neurofilament among the intermediate filament family / Takahiro Gotow -- Neurofilament transport / Andrew J. Grierson and Christopher C.J. Miller -- Knockout models of neurofilament proteins / Rodolphe Perrot and Jean-Pierre Julien -- Neurofilaments and radial growth: deconstruction of a hypothesis through the construction of gene targeted mice / Michael L. Garcia and Devin M. Barry -- Deregulation of cytoskeletal protein phosphorylation and neurodegeneration / Jyotshnabala Kanungo ... [et al.] -- Neurofilaments in aged animals / Shin-ichi Hisanaga, Takahiro Sasaki, and Atsuko Uchida -- Neurofilament changes in multiple sclerosis / Elizabeth Gray and Alastair Wilkins -- Intermediate filament interactions in neurons / Kevin G. Young and Rashmi Kothary -- Tropomyosins in neuronal morphogenesis and development / Nikki Margarita Curthoys, Peter William Gunning, and Thomas Fath -- The driving machinery for growth cone navigation / Takuro Tojima and Hiroyuki Kamiguchi -- Glial fibrillary acidic protein: the intermediate filament protein of astrocytes / Douglas L. Eng and Lawrence F. Eng -- Axonal transport mechanisms in cytoskeleton formation and regulation / Aidong Yuan and Ralph A. Nixon -- Axonal transport and motor neuron disease / Anna-Lena Ström ... [et al.] -- In vivo imaging of axonal transport in aging and Alzheimer's disease / Donna J. Cross and Satoshi Minoshima -- Regulation of cytoskeletal composition in neurons: transcriptional and post-transcriptional control in development, regeneration, and disease / Ben G. Szaro and Michael J. Strong -- Crosstalks between myelinating cells and the axonal cytoskeleton / Rodolphe Perrot and Joël Eyer -- Topographic regulation of neuronal intermediate filament proteins by phosphorylation: in health and disease / Parvathi Rudrabhatla and Harish C. Pant -- Cytoskeleton, axonal transport, and the mechanisms of axonal neuropathy / Hsinlin T. Cheng ... [et al.] -- Effects of insulin on tau and neurofilament / R. Schechter and K.E. Miller -- Ethanol effects on the cytoskeleton of nerve tissue cells / Sergio G. Evrard and Alicia Brusco.