Lane Medical Library

Section I - Anatomy and physiology of bone -- Section II - Measurement tools in osteoporosis and arthritis -- Section III - Bone loss and fragility fractures in the rheumatic diseases -- Section IV - Bone loss due to medications -- Section V - Management of bone loss in patients with rheumatic diseases -- Section VI - Other bone disorders.

Bone disease after kidney transplantation / S.L-S Fan and John Cunningham -- Histologic abnormalities of bone before and after kidney transplantation / Marie-Claude Monier-Faugere and Hartmut H. Malluche --Bone disease following kidney-pancreas and pancreas transplantation / Stuart M. Sprague -- Bone disease after liver transplantation / Nuria Guañabens and Ana Monegal -- Bone disease in patients before and after cardiac transplantation / Adi Cohen and Elizabeth Shane -- Bone loss in patients before and after lung transplantation / Emily Stein and Elizabeth Shane -- Transplantation for cystic fibrosis: effect on the skeleton / Robert M. Aris and David A. Ontjes -- Bone disease after bone marrow transplantation / Peter R. Ebeling -- Osteonecrosis and organ transplantation / Neveen A.T. Hamdy -- Pediatric transplant bone disease / Mary B. Leonard and Craig B. Langman -- -- Management of bone disease in candidates for organ transplant / Susan M. Ott -- Management: prevention of bone loss after organ transplantation / Philip Sambrook -- Management: established osteoporosis in organ transplant recipients / Ian R. Reid.Principles of transplantation immunology / Mario C. Deng ... [et al.] -- Bone biology: bone structure and remodeling / Lawrence G. Raisz -- Skeletal effects of glucocorticoids: basic and clinical aspects / Ernesto Canalis -- Transplantation bone disease induced by non-steroid immunosuppressants / Solomon Epstein, Angela M. Inzerillo, and Mone Zaidi -- Molecular effects of calcineurin inhibitors / Adina E. Schneider, Mone Zaidi, and Solomon Epstein -- Bone and the immune system / W. Neale Weitzmann and Roberto Pacifici -- -- Fracture prevalence and incidence in solid organ transplant recipients / Bart L. Clarke and Gudrun Leidig-Bruckner -- Bone histomorphometetry and its application to transplantation bone disease / Juliet Compston -- The role of parathyroid hormone in the evolution of bone loss after organ transplantation / Mishaela R. Rubin and John P. Bilezikian -- The role of hypogonadism in the evolution of bone loss before and after cardiac transplantation / Hans-Ulrich Stempfle -- Pathogenesis of transplantation bone disease: a unifying hypothesis / Richard Eastell, Kim E. Naylor, and Annie M. Cooper --

"This book provides a rational basis for understanding how to ensure adequate bone health in children. It discusses the recommended dietary intakes of calcium and vitamin D in pediatric health as well as appropriate sources of these nutrients. The text presents information on the maintenance and improvement of bone health in children and adolescents. Chapters cover peak bone mass and prevention of bone loss diseases; bone formation; nutritional needs for calcium and vitamin D based on age; additional key nutrients needed for healthy bones; exercise and management of chronic illnesses; genetics and bone health; and future directions towards targeted dietary recommendations"--Provided by publisher.

The normal bone marrow -- Special techniques applicable to bone marrow diagnosis -- Infection and reactive changes -- Acute myeloid leukaemia, mixed phenotype acute leukaemia, the myelodysplastic syndromes, and histiocytic neoplasms -- Myeloproliferative and myelodysplastic/myeloproliferative neoplasms and related conditions -- Lymphoproliferative disorders -- Plasma cell neoplasms -- Disorders of erythropoiesis, granulopoiesis and thrombopoiesis -- Miscellaneous disorders -- Metastatic tumours -- Diseases of bone.

Overview / Sadmeet Singh and Gurmit Singh -- Parathyroid hormone-related peptide and malignancy / David Goltzman -- Vitamin D and vitamin D analogs in cancer / Richard Kremer and Shafaat A. Rabbani -- Role of TGF and IGF in tumor progression and bone metastases / Erin Giles and Gurmit Singh -- Biologic and therapeutic implications of osteomimicry and epithelial/mesenchymal transition in prostate cancer / Wen-Chin Huang, Valerie Odero-Marah, and Leland W.K. Chung -- The roles of immune-cell derived matrix metalloproteinases in tumor growth and metastasis / Kristina A. Szabo and Gurmit Singh -- Contribution of osteopontin to the development of bone metastasis / Alison L. Allan ... [et al.] -- The role of interleukin-11 in osteolytic bone metastasis / Ryan R. Simon ... [et al.] -- Cell adhesion moleculars in tumor metastasis / Sujata Persad ... [et al.] --Antithrombotics in tumor growth and metastasis / Shaker A. Mousa -- Challenges and strategies in the analysis of multiple events in oncology / Pierre P. Major and Richard J. Cook -- Integrins : novel targets for the treatment of bone metastasis / Graham C. Parry ... [et al.] -- Bone metastasis and pathological fractures : bone tissue engineering as a novel therapy / Laurie A. McDuffee, Nigel Colterjohn, and Gurmit Singh -- Role of photodynamic therapy for bone metastasis / Shane Burch and Albert J.M. Yee -- Docetaxel for metastatic cancer and its role in combination therapies for advanced prostate cancer / Ellen K. Wasan ... [et al.] -- The use of tetracyclines for bone metastasis / Eric Seidlitz, Zeina Saikali, and Gurmit Singh -- Role of bisphosphonates in skeletal metastases / Arif Hussain and Fred Saad -- Radiation treatment of bone metastases / Edward Chow, Jackson Wu, and Elizabeth Toni Barnes.

Bone structure, development and bone biology -- Structure and function of joints -- Biomechanics: part I -- Biomechanics: part II -- Laboratory in orthopedic practice -- Genetics and molecular biology of bone and soft tissue tumors -- Grossing of bone and soft tissue (common specimens and procedures) -- Bone histomorphometry and undecalcified sections -- Radiology of the musculoskeletal system -- Skeletal trauma and common orthopedic problems -- Surgical pathology of bone infections -- Arthropathies -- Surgical pathology of prosthetic materials -- Osteoporosis and metabolic bone disease -- Inherited and dysplastic conditions of the skeleton -- Musculoskeletal neoplasms: an introduction -- Medical management of sarcomas -- Radiation therapy for sarcomas -- Surgical pathology of bone tumors and tumor-like lesions -- Tumors of soft tissue.

Bone dynamics: morphogenesis, growth modeling, and remodeling / Jeffrey O. Hollinger -- Fracture repair / Charles Sfeir ... [et al.] -- Common molecular mechanisms regulating fetal bone formation and adult fracture repair / Theodore Miclau ... [et al.] -- Biology of bone grafts / Victor M. Goldberg and Sam Akhavan -- Cell-based strategies for bone regeneration: from developmental biology to clinical therapy / Scott P. Bruder and Tony Scaduto -- Biology of the vascularized fibular graft / Elizabeth Joneschild and James R. Urbaniak -- Growth factors and osteogenesis / Stephen B. Trippel -- Bone grafts and bone graft substitutes / Doug Sutherland and Mathias Bostrom --Gene transfer approaches to enhancing bone healing / Oliver Betz ... [et al.] -- Bone morphogenic proteins and other growth factors to enhance fracture healing and treatment of nonunions / Calin S. Moucha and Thomas A. Einhorn -- The Ilizarov technique for bone regeneration and repair / James Aronson -- Spinal fusion: biology and clinical applications / K. Craig Boatright and Scott D. Boden -- Bone allograft transplantation: theory and practice / Henry J. Mankin ... [et al.] -- Bone grafting for total joint arthroplasty: biology and clinical applications / Moussa Hamadouche and Daniel J. Berry -- Biophysical stimulation using electrical, electromagnetic, and ultrasonic fields: effects on fracture healing and spinal fusion / James T. Ryaby -- Vascularized fibula grafts: clinical applications / Richard S. Gilbert and Scott W. Wolfe -- Craniofacial repair / Bruce A. Doll ... [et al.] -- Bone regeneration techniques in the orofacial region / Samuel E. Lynch.

Osteoclast: origin and differentiation /Janet Rubin and Edward M. Greenfield --Osteolytic enzymes of osteoclasts /Merry Jo Oursler --Regulation of osteoclast activity /Roland Baron and William C. Horne --Structural aspects of bone resorption /Steven D. Bain and Ted S. Gross --Inflammatory cytokines /Mark S. Nanes and Roberto Pacifici --Genetics and mutations affecting osteoclast development and function /Mark C. Horowitz, Melissa A. Kacena, Joseph A. Lorenzo --Clinical disorders associated with alterations in bone resorption /Janet Rubin and Mark S. Nanes --Pharmaceuticals for bone disease targeting the osteoclast /Lorraine A. Fitzpatrick --Skeletal complications of malignancy: central role for the osteoclast /Gregory A. Clines, John M. Chirgwin, Theresa A. Guise.

Introduction to Bone Tumors --How to Evaluate a Bone Lesion --Imaging Modalities --Cartilage Tumors --Osseous Tumors --Fibrous Tumors --Miscellaneous Tumors --Bone Metastases --Bone Tumor Mimickers --Cases.

Introduction -- Evolution of the Miocene great apes -- Later Miocene and Pliocene hominids -- Our kind of hominins -- A systematic scheme for the Pliocene and Early Pleistocene hominids -- The first African exodus : the emergence of early homo in Europe and Asia -- Human evolution in the Middle Pleistocene -- "The grisly folk" : the emergence of the Neanderthals -- The second African exodus : the emergence of modern humans -- The emergence of modern humans in Asia and in Australia -- Epilogue.

The bonobo's adaptive potential : social relations under captive conditions / Jeroen M.G. Stevens, Hilde Vervaecke and Linda Van Elsacker -- What does agonistic dominance imply in bonobos? / Tommaso Paoli and Elisabetta Palagi -- Social play in bonobos : not only an immature matter / Elisabetta Palagi and Tommaso Paoli -- Gestures and multimodal signaling in bonobos / Amy S. Pollick, Annette Jeneson and Frans B.M. de Waal -- Longitudinal structure of a unit-group of bonobos : male philopatry and possible fusion of unit-groups / Chie Hashimoto ... [et al.] -- Seasonal changes in fruit production and party size of bonobos at Wamba / Mbangi Mulavwa ... [et al.] -- Relationships among fruit abundance, ranging rate, and party size and composition of bonobos at Wamba / Takeshi Furuichi ... [et al.] -- Bonobo (Pan paniscus) density estimation in the SW-Salonga National Park, Democratic Republic of Congo : common methodology revisited / Meike Mohneke and Barbara Fruth -- Ecological factors influencing bonobo density and distribution in the Salonga National Park : applications for population assessment / Gay Edwards Reinartz ... [et al.] -- Range occupation and population estimates of bonobos in the Salonga National Park : application to large-scale surveys of bonobos in the Democratic Republic of Congo / Falk Grossmann ... [et al.] -- Traditional land-use practices for bonobo conservation / Jo Myers Thompson, Lubuta Mbokoso Nestor and Richard Bovundja Kabanda -- Human hunting and its impact on bonobos in the Salonga National Park, Democratic Republic of Congo / John A. Hart ... [et al.] -- The bonobos of the Lake Tumba-Lake Maindombe hinterland : threats and opportunities for population conservation / Bila-Isia Inogwabini ... [et al.] -- Changes in the status of bonobos, their habitat, and the situation of humans at Wamba in the Luo Scientific Reserve, Democratic Republic of Congo / Gen'ichi Idani ... [et al.] -- The conservation value of Lola ya Bonobo sanctuary / Claudine André ... [et al.].

Ethical foundations of substance abuse treatment / Cynthia M.A. Geppert, Laura Weiss Roberts -- The therapeutic relationship in substance abuse treatment / Jennifer Knapp Manuel, Alyssa A. Forcehimes -- The ethics of harm reduction / William R. Miller -- Ethical issues in the treatment of persons with co-occurring disorders / Christie A. Cline, Kenneth Minkoff -- Cultural and spiritual dimensions of addiction treatment / Kamilla L. Venner, Michael P. Bogenschutz -- Forensic issues in the treatment of addictions / Joseph B. Layde -- Ethical issues in the treatment of women with substance abuse / Diane T. Castillo, Ann Waldorf -- Ethical aspects of the treatment of substance abuse in children and adolescents / Jerald Belitz -- Ethical dilemmas in treating chronic pain in the context of addiction / Joanna G. Katzman, Cynthia M.A. Geppert.

Radiobiologic concepts for brachytherapy / Alexandra J. Stewart and Bleddyn Jones -- Technical physics support for brachytherapy / Robert A. Cormack ... [et al.] -- Head and neck brachytherapy / Peter Han ... [et al.] -- Central nervous system brachytherapy / Arnab Chakravarti, Thomas F. DeLaney, and Jay S. Loeffler -- Breast brachytherapy / Joseph R. Kelley ... [et al.] -- Thoracic brachytherapy / Subhakar Mutyala and David J. Sugarbaker -- Gastrointestinal brachytherapy / Brian G. Czito ... [et al.] -- Prostate brachytherapy / Caroline L. Holloway ... [et al.] -- Gynecologic brachytherapy / Akila N. Viswanathan and Daniel G. Petereit -- Soft tissue sarcoma brachytherapy / Chandrajit P. Raut and Michele Albert -- Vascular brachytherapy / Huan Giap and Prahbakar Tripuraneni -- Role of brachytherapy in pediatrics / Thomas E. Merchant and Matthew J. Krasin -- Establishing a brachytherapy practice / Gerard Walsh ... [et al.].

Changes in cognitive function in human aging / Elizabeth Glisky -- Successful versus unsuccessful cognitive aging in Rhesus monkeys / Mark B. Moss ... [et al.] -- Neuropsychology of cognitive aging in rodents / Joshua S. Rodefer -- Design-based stereology in brain aging research / Cristoph Schmitz -- The effects of normal aging on nerve fibers and neuroglia in the central nervous system / Alan Peters -- Neurogenesis in the adult and aging brain / David R. Riddle -- Expression profile analysis of brain aging / Steve Ginsberg -- Subtle alterations in glutamatergic synapses underlie the aging-related declines in hippocampal function / Lei Shi, Michelle Adams, and Judy Brunso-Bechtold -- Assessment of second messenger function in the hippocampus of aged rats with cognitive impairment / Michelle M. Nicolle, H. Zhang, Jennifer L. Bizon -- Neurophysiology of old neurons and synapses / Ashok Kumar and Thomas C. Foster -- Imaging cognition in the aging human brain / Trey Hedden -- Regulation of cerebrovascular aging / William Sonntag, Jeremy Ingraham, and Delrae Eckman -- Stress and glucocorticoid contributions to normal and pathological aging / Ki A. Goosens and Robert Sapolsky -- Altered calcium homeostasis in old neurons / Emil Toescu -- Oxidative stress in aging / Jennifer Vila and Paula C. Bickford.Changes in cognitive function in human aging / Elizabeth L. Glisky -- Successful vs. unsuccessful aging in the Rhesus monkey / Mark B. Moss ... [et al.] -- Neuropsychology of cognitive aging in rodents / Joshua S. Rodefer and Mark G. Baxter -- Design-based stereology in brain aging research / Cristoph Schmitz and Patrick R. Hof -- The effects of normal aging on nerve fibers and neuroglia in the central nervous system / Alan Peters -- Neurogenesis in the adult and aging brain / David R. Riddle and Robin J. Lichtenwalner -- Expression profile analysis of brain aging / Stephen D. Ginsberg -- Subtle alterations in glutamatergic synapses underlie the aging-related decline in hippocampal function / Lei Shi, Michelle Adams, and Judy K. Brunso-Bechtold -- Assessment of second messenger function in the hippocampus of aged rats with cognitive impairment / Michelle M. Nicolle, Hai-Yan Zhang, and Jennifer L. Bizon -- Neurophysiology of old neurons and synapses / Ashok Kumar and Thomas C. Foster -- Imaging cognition in the aging human brain / Trey Hedden -- Regulation of cerebrovascular aging / William E. Sonntag ... [et al.] -- Stress and glucocorticoid contributions to normal and pathological aging / Ki A. Goosens and Robert M. Sapolsky -- Altered calcium homeostasis in old neurons / Emil C. Toescu -- Oxidative stress and the aging brain: from theory to prevention / Carmelina Gemma ... [et al.].

History of brain death -- Neurology of brain death -- Beliefs about brain death -- Critics and brain death -- Procurement after brain death -- Clinical problems in brain death.

The development of the Drosophila larval brain -- Anteroposterior regionalization of the brain: genetic and comparative aspects -- Dorsoventral patterning of the brain: a comparative approach -- Dissection of the embryonic brain using photoactivated gene expression -- Design of the larval chemosensory system -- Development of the Drosophila olfactory system -- The olfactory sensory map in drosophila -- Optic lobe development -- Clonal unit architecture of the adult fly brain.

Brain imaging in behavioral medicine and clinical neuroscience: an introduction -- Basic MR physics: considerations for behavioral medicine and neurophysiology -- Functional magnetic resonance imaging -- Diffusion-tensor imaging and behavioral medicine -- Perfusion MRI -- Proton magnetic resonance spectroscopy: a practical guide for the clinical neuroscientist -- Functional near-infrared spectroscopy -- Methodological considerations for using bold fMRI in the clinical neurosciences -- Application of functional neuroimaging to examination of nicotine dependence -- Relationship between mood, stress, and tobacco smoking -- Imaging substance use and misuse: psychostimulants -- Eating disorders -- Structural and functional neuroimaging in obesity -- Neuropsychology and neuroimaging in metabolic dysfunction -- Neuroimaging of cardiovascular disease -- Exercise and the brain -- Neuroimaging of pain: a psychosocial perspective -- Neuroimaging in acute ischemic stroke -- Neuroimaging of Alzheimer's disease, mild cognitive impairment, and other dementias -- Application of neuroimaging methods to define cognitive and brain abnormalities associated with HIV -- Neuroimaging and cognitive function in multiple sclerosis -- Neuroimaging of fatigue -- Brain imaging in behavioral medicine and clinical neuroscience: synthesis.

The Cytokine System --The Discovery of the Brain Immunomodulators --Brain Neuroendocrine Immune System: Neurosecretion of Interleukins and New Cytokines Produced by NSO and NPV of Hypothalamus --Antibacterial and Antiviral Activity of PRP-1 (Galarmin) and Some Immunological Mechanisms of its Action --Treatment and Prophylaxis of Anthrax by Galarmin: Receptor Tyrosine Kinases is a Target of Galarmin --Prophylaxis and Treatment of Methicillin-Resistant Staphylococcus Aureus (MRSA) Infection with Proline-Rich Polypeptides Galarmin and Its Structural Analogues in an Experimental Murine Model --Treatment of Clostridium Perfringens-induced Gas Gangrene by New Cytokines of Brain --Hypothalamic, Proline-Rich Polypeptide (Galarmin) has Protective and Immunogenic Activity on Experimental Mycobacterium Tuberculosis Infection --Brain-Bone Marrow Neurohumoral Axis: Galarmin Controls Differentiation, Proliferation and Mobilization of Bone Marrow Progenitor cells --Antioxidant-Antiradical and Electron Donating Function of Galarmin and Gx-NH2 --Discussion --Summary.

pt. 1.What educators need to know about the brain --1.Introduction and conceptual foundations --2.General principles of microstructure and microfunction --3.General principles of macrostructure and macrofunction --4.General principles of brain development --pt. 2.Linking brain research to literacy research --5.Building a reading brain neurologically --6.Building a writing brain neurologically --7.Building a computing brain neurologically --pt. 3.Linking literacy research to brain research --8.Building a reading brain pedagogically --9.Building a writing brain pedagogically --10.Building a computing brain pedagogically --pt. 4.Educational applications of brain-literacy links --11.Implications for educational policy --12.Implications for classroom practice.

Making the lifetime connection between brain and machine for restoring and enhancing function -- Out of the frying pan into the fire: the P300-based BCI faces real-world challenges -- Toward a whole-body neuroprosthetic -- Biocompatible multichannel electrodes for long-term neurophysiological studies and clinical therapy: novel concepts and design -- Deep brain stimulation: BCI at large, where are we going to? -- Deep brain stimulation: emerging indications -- Development of neuromodulation treatments in a large animal model: Do neurosurgeons dream of electric pigs? -- Few examples of the contribution of animal research in rodents for clinical application of deep brain stimulation -- Cochlear implants: matching the prosthesis to the brain and facilitating desired plastic changes in brain function -- Multimodal, longitudinal assessment of intracortical microstimulation -- Functional consequences of chronic, physiologically effective intracortical microstimulation -- Reducting surface area while maintaining implant penetrating profile lowers the brain foreign body response to chronically implanted planar silicon microelectrode arrays -- Can histology solve the riddle of the nonfunctioning electrode? Factors influencing the biocompatibility of brain machine interfaces -- Changes in CNS structures after spinal cord lesions: implications for BMI -- Modeling the potentiality of spinal-like circuitry for stabilization of a planar arm system -- Advances in the use of electrical stimulation for the recovery of motor function -- Intraspinal microstimulation for the recovery of function following spinal cord injury -- Interfacing neurons with carbon nanotubes: (re)engineering neuronal signaling -- Nanomodified surfaces and neurite outgrowth -- Direct local polymerization of poly(3,4-ethylenedioxythiophene) in rat cortex.

Molecular and biochemical basis of brain injury following heart surgery: interventions for the future -- Cardiopulmonary bypass circuit and the brain -- Neurological and cognitive sequelae of cardiac surgery -- Neurocognitive decline following cardiac surgery: incidence, risk factors, prevention, and outcomes -- Neuropathology of brain injury in cardiac surgery -- Biochemical markers of brain injury -- Pitfalls of neuropsychometric assessment and alternative investigative approaches -- Imaging of the brain in cardiac surgery as a tool in brain protection studies -- Current techniques of emboli detection and their utility in brain protection studies -- Intraoperative brain monitoring in cardiac surgery -- Near-infrared spectroscopy monitoring in cardiac surgery: theory, practice, and utility -- The design and methodology of clinical studies on neuroprotection in cardiac surgery -- Temperature and brain protection in cardiac surgery -- Studies of nonpharmacological interventions to reduce brain injury -- Pharmacological studies to reduce brain injury in cardiac surgery -- Off-pump and on-pump coronary artery surgery and the brain -- Experimental basis and clinical studies of brain protection in pediatric heart surgery -- Experimental basis and clinical studies of brain protection in aortic arch surgery -- The future of brain protection in cardiac surgery.

Cell cycle activation in neurons: the final exit of brain-morpho-dysregulation / Thomas Arendt -- Paved with good intentions: the link between cell cycle and cell death in the mammalian central nervous system / Yan Yang and Karl Herrup -- The role of presenilins in the cell cycle and apoptosis / Mervyn J. Monteiro -- Cell cycle activation and cell death in the nervous system / Zsuzsanna Nagy -- Cell cycle and chromosome segregation defects in Alzheimer's disease / Huntington Potter -- Alzheimer disease: a new beginning or a final exit? / Mark E. Obrenovich ... [et al.] -- From cell cycle activation to the inhibition of the Wnt pathway: a hypothesis of how neurons die in response to b-Amyloid / Agata Copani ... [et al.].

Epidemiology of brain tumors / Randa El-Zein, Melissa Bondy, and Margaret Wrensch -- Molecular genetics of tumors of the central nervous system / C. David James -- Molecular pathology of nervous system tumors / Catherine L. Nutt ... [et al.] -- Genetic modeling of glioma formation in mice / Martin Begemann ... [et al.] -- Biology of brain metastasis / Minsoo Kang ... [et al.] -- Analysis of neural precursor cells in the context of origin of brain tumors, their treatment, and repair of treatment-associated damage / Mark Noble and Joerg Dietrich -- Biology of primitive neuroectodermal tumors / John R. Hill, Shoichiro Ohta, and Mark A. Israel -- Molecular and cellular biology of the blood-brain barrier and its characteristics in brain tumors / Helga E. de Vries ... [et al.] -- Immune regulation in the brain : lessons from autoimmunity and implications for brain tumor therapy / Lois A. Lampson -- Genetic pathways in the evolution of gliomas / Hiroko Ohgaki and Paul Kleihues -- DNA damage and repair in the therapeutic response of tumors of the central nervous system / Henry S. Friedman, M. Eileen Dolan, and Francis Ali-Osman -- Role of urokinase-type plasminogen activator receptor in human glioma invasion / Sanjeeva Mohanam and Jasti S. Rao -- Regulation of the cell cycle and apoptosis in human brain tumors / Juan Fueyo, Candelaria Gomez-Manzano, and Timothy J. McDonnell -- Systemic chemotherapy for metastatic tumors of the central nervous system / Charles A. Conrad and W.K. Alfred Yung -- Radiation biology and therapy of tumors of the central nervous system / Nalin Gupta ... [et al.] -- Advances in the management of cerebral metastases / Fadi Hanbali and Raymond Sawaya -- Immunotherapy of central nervous system tumors: contemporary cancer research / Amy B. Heimberger ... [et al.] -- Targeting drugs to tumors of the central nervous system / Maciej S. Lesniak, James Frazier, and Henry Brem -- Rational design and development of targeted brain tumor therapeutics / Francis Ali-Osman ... [et al.].

Meet the increasing need for effective brain tumor management with the highly anticipated revision of Brain Tumors by Drs. Andrew H. Kaye and Edward R. Laws. Over the past decade, enormous advances have been made in both the diagnosis and the surgical and radiotherapeutic management of brain tumors. This new edition guides you through the latest developments in the field, including hot topics like malignant gliomas, functional brain mapping, neurogenetics and the molecular biology of brain tumors, and biologic and gene therapy. You'll also have easy access to the complete contents online, with links to PubMed and a downloadable image library, at www.expertconsult.com. Benefit from the knowledge and experience of Drs. Andrew H. Kaye and Edward R. Laws, globally recognized experts in the field of neurosurgery, as well as many other world authorities.

Sect. ISaccadic eye movements /section editor, D.P. Munoz --1.Vying for dominance: dynamic interactions control visual fixation and saccadic initiation in the superior colliculus --2.Neural control of saccades --3.The latency of saccades toward auditory targets in humans --4.Contribution of the primate prefrontal cortex to the gap effect --5.Influence of stimulus characteristics on the latency of saccadic inhibition --6.Commentary: Saccadic eye movements: overview of neural circuitry --Sect. II.Change blindness and transsaccadic integration /section editor, J. Hyönä --7.Converging evidence for the detection of change without awareness --8.Blinks, blanks and saccades: how blind we really are for relevant visual events --9.Multiple-object permanence tracking: limitation in maintenance and transformation of perceptual objects --10.What information survives saccades in the real world? --11.Transsaccadic memory of position and form --12.Transsaccadic memory for visual object detail --13.Commentary: Changes --Sect. III.Smooth pursuit eye movements /section editors, W. Heide and D.P. Munoz --14.Non-target influences on the initiation of smooth pursuit eye movements --15.Integration of motion cues for the initiation of smooth pursuit eye movements --16.The role of expectancy and volition in smooth pursuit eye movements --19Commentary: Smooth pursuit eye movements: from low-level to high-level vision --Sect. IV. Eye-hand coordination /section editor, R. Radach --20.Cortical frames of reference for eye-hand coordination --21.Neuropsychological perspectives on eye-hand coordination in visually-guided reaching --22.Visuomotor transformations for eye-hand coordination --23.Implications of distracter effects for the organization of eye movements, hand movements, and perception --24.Visual short-term memory and motor planning --25.Commentary: Coordination of eye and hand in time and space --Sect. V.Clinical aspects of eye movement research /section editor, W. Heide --26.Visual search in long-term cannabis users with early age of onset --27.Visual search in patients with left visual hemineglect --28.Saccadic adaptation in neurological disorders --29.Saccade sequences as markers for cerebral dysfunction following mild closed head injury --30.Cognition and the inhibitory control of saccades in schizophrenia and Parkinson's disease --31.Control of volitional and reflexive saccades in Tourette's syndrome --32.Oculomotor control in a group of very low birth weight (VLBW) children --33.A new framework for investigating both normal and abnormal eye movements --34.Commentary: Eye movement research with clinical populations --Subject index.

A. Introduction / Harry Whitaker, C.U.M. Smith, and Stanley Finger -- Chronology / C.U.M. Smith -- B. Background. Introduction / The editors -- Brain and mind in the 'long' eighteenth century / C.U.M. Smith -- Enlightening neurosciences : microscopes and microscopy in the eighteenth century / Brian J. Ford -- Corpus curricula : medical education and the voluntary hospital movement / Jonathan Reinarz -- Some thoughts on the medical milieu in the last quarter of the eighteenth century as reflected in the life and activities of James Parkinson (1755-1824) / Christopher Gardner-Thrope --C. The nervous system. Introduction / The editors -- John Hunter's contribution to neuroscience / James L. Stone, James T. Goodrich, and George R. Cybulski -- William Cullen (1710-1790) and Robert Whytt (1714-1766) on the nervous system / Julius Rocca -- 1710 : the introduction of experimental nervous system physiology and anatomy by François Pourfour du Petit / Lawrence Kruger and Larry W. Swanson -- Irritable glue: the Haller-Whytt controversy on the mechanism of muscle contraction / Eugenio Frixione -- The taming of the electric ray : from an wonderful and dreadful "art" to "animal electricity" and "electric battery" / Marco Piccolino -- Luigi Galvani, physician, surgeon, physicist: from animal electricity to electro-physiology / Miriam Focaccia and Raffaella Simili -- D. Brain and behavior. Introduction / The editors -- The vision of William Porterfield / Nicholas J. Wade -- David Hartley's neural vibrations and psychological associations / Robert B. Glassman and Hugh W. Buckingham -- Charles Bonnet's neurophilosophy / Harry A. Whitaker and Yves Turgeon -- Swedenborg and localization theory / Ulf Norrsell --E. Medical theories and applications. Introduction / The editors -- Neuroscience in the work of Boerhaave and Haller / Peter J. Koehler -- Apoplexy : changing concepts in the eighteenth century / Catherine E. Storey -- Benjamin Franklin and the electrical cure for disorders of the nervous system / Stanley Finger -- Gentleman's magazine, the advent of medical electricity, and disorders of the nervous system / Hannah Sypher Locke and Stanley Finger -- Therapeutic attractions: early applications of electricity to the art of healing / Paola Bertucci -- John Wesley on the estimation and cure of nervous disorders / James G. Donat -- Franz Anton Mesmer and the rise and fall of animal magnetism : dramatic cures, controversy, and ultimately a triumph for the scientific method / Douglas J. Lanska and Joseph T. Lanska -- Hysteria in the eighteenth century / Diana Faber --F. Cultural consequences. Introduction / The editors -- Technological metaphors and the anatomy of representations in eighteenth-century French materialism and dualist mechanism / Timo Kaitaro -- Explorations of the brain, mind and medicine in the writings of Jonathan Swift / Marjorie Perlman Lorch -- Temperament and the long shadow of nerves in the eighteenth century / George Rousseau.

Why a book on branching, and why now? / Jamie A. Davies -- Branching morphogenesis in vertebrate neurons / Katherine M. Kollins and Roger W. Davenport -- Branching of single cells in arabidopsis / Daniel Bouyer and Martin Hülskamp -- Branching in fungal hyphae and fungal tissues: growing mycelia in a desktop computer / David Moore, Liam J. McNulty, and Audrius Meskauskas -- Branching in colonial hydroids / Igor A. Kosevich -- How is the branching of animal blood vessels implemented? / Sybill Patan -- Extracellular matrix remodeling in mammary gland branching morphogenesis and breast cancer: the double-edged sword / Eva A. Turley and Mina J. Bissell --Branching morphogenesis in mammalian kidneys / Jamie A. Davies -- Embryonic salivary gland branching morphogenesis / Tina Jaskoll and Michael Melnick -- Branching morphogenesis of the prostate / A.A. Thomson and P.C. Marker -- Uterine glands / Thomas E. Spencer ... [et al.] -- Physical mechanisms of branching morphogenesis in animals: from viscous fingering to cartilage rings / Vincent Fleury ... [et al.].

Registration for examinations -- Test-taking tips -- Internal medicine -- Pediatrics -- Obstetrics and gynecology -- Psychiatry -- Surgery -- Geriatrics -- Pictorial atlas -- Clinical problem set 1 -- Clinical problem set 2 -- Clinical problem set 3.

"Bratton's Family Medicine Board Review, Fourth Edition, is a directed review of important topics that typically appear on American Board of Family Medicine (ABFM) in-training examinations, board certification examinations, and recertification examinations. This material is not intended for a comprehensive review but, instead, should direct the examinee to areas of weakness that may need further review. Family medicine is a broad field, and to provide a complete, comprehensive review of all topics that may be covered is extremely time consuming if not impossible. Several other courses attempt to provide this type of review; however, this book is more abbreviated and focuses on topics that are commonly found on board examinations. Adequate preparation for any test is the key to success and rewarding results. Given this, we all know the importance of practice tests and the benefits of testing our knowledge base before the actual examination. This review book is structured for the examinee with limited time and resources for review and should be used only by those individuals with an established foundation of knowledge within the field of family medicine. Its primary purpose is to identify areas of weakness that can be improved on"--Provided by publisher.

The theory of the sick lobe -- Lobar anatomy of human breast and its importance for breast cancer -- Breast cancer may originate in utero: the importance of the intrauterine environment for breast cancer development -- Genetic alterations in normal and malignant breast tissue -- The role of ductal lavage: a cautionary tale -- The distribution of the earliest forms of breast carcinoma -- The implications of the imaging manifestations of multifocal and diffuse breast cancers -- Lobar ultrasound of the breast -- The lobar distribution of the lesions in breast carcinoma: ductoscopy and surgery -- Strop breast cancer now!: imagining imaging pathways towards search, destroy, cure, and watchful waiting of premetastasis breast cancer -- Epilogue: the diseased breast lobe in the context of X-chromosome inactivation and differentiation waves.

Overview -- Common benign conditions of low concern -- Benign conditions associated with a risk for the subsequent development of cancer -- Precursor lesions and noninvasive cancers -- Breast cancer -- Things pathologists must always consider -- Nuances and details of the pathology report.

Overview of resistance to systemic therapy in patients with breast cancer / Ana Maria Gonzalez-Angulo, Flavia Morales-Vasquez and Gabriel N. Hortobagyi -- Roles of multidrug resistance genes in breast cancer chemoresistance / M. Tien Kuo -- Therapy-induced apoptosis in primary tumors / David J. McConkey -- Cell cycle deregulation in breast cancer: insurmountable chemoresistance or achilles' heel? / Laura Lambert and Khandan Keyomarsi -- p53, BRCA1 and breast cancer chemoresistance / Kimberly A. Scata and Wafik S. El-Deiry -- Integrin-mediated adhesion: tipping the balance between chemosensitivity and chemoresistance / Mary M. Zutter --Insulin-like growth factors and breast cancer therapy / Xianke Zeng and Douglas Yee -- EGF receptor in breast cancer chemoresistance / Robert B. Dickson and T.B. Deb -- Molecular mechanisms of ErbB2-mediated breast cancer chemoresistance / Ming Tan and Dihua Yu -- Estrogen receptors in resistance to hormone therapy / Matthew H. Herynk and Suzanne A.W. Fuqua -- Novel approaches for chemosensitization of breast cancer cells: the E1A story / Yong Liao, Dihua Yu and Mien-Chie Hung.

Global burden of breast cancer / Jacques Ferlay ... [et al.] -- Breast cancer biology and clinical characteristics / Amanda I. Phipps and Christopher I. Li -- In situ breast cancer / Brian L. Sprague and Amy Trentham-Dietz -- Endogenous hormones / Amanda I. Phipps and Christopher I. Li -- Exogenous hormones / Christopher I. Li and Elisabeth F. Beaber -- Reproductive factors / Mats Lambe -- Physical activity and anthropometric factors / Katherine D. Henderson, Jennifer Prescott, and Leslie Bernstein -- Diet and nutrition / Martin Lajous and Shumin M. Zhang -- Environmental and occupational exposures / Amanda I. Phipps ... [et al.] -- Shift work and circadian disruption / Scott Davis and Dana K. Mirick -- Non-hormonal medications and chronic diseases / Patricia F. Coogan -- Male breast cancer / Ian S. Fentiman -- Inherited predisposition: familial aggregation and high risk genes / Kathleen E. Malone and Kerryn W. Reding -- Common genetic susceptibility loci / Mikkel Z. Oestergaard and Paul Pharoah -- Mammographic density as a potential surrogate marker for breast cancer / Norman F. Boyd, Lisa J. Martin, and Salomon Minkin -- Breast cancer screening / Karla Kerlikowske -- Principles of breast cancer therapy / Allison W. Kurian and Robert W. Carlson -- Breast cancer outcomes / Graham A. Colditz and Courtney Beers.

Female breast cancer in California, an overview / Cyllene R. Morris, Sandy L. Kwong -- Risk factors for female breast cancer / Rosemary D. Cress -- Demographic aspects of breast cancer incidence and mortality in California, 1988-1999 / Sharan L. Campleman, Robyn L. Curtis -- Socioeconomic status and breast cancer incidence in California / Kathleen Yost -- Trends in female breast cancer incidence and mortality in California / Kiumarss Nasseri -- Risk of developing invasive femal breast cancer in California / Cyllene R. Morris -- Utilization of screening mammography in California, 1987-2000 / Holly Hoegh, Bonnie D. Davis -- State at diagnosis of female breast cancer in California, 1988-1999 / Paul K. Mills, Ratnali Jain -- Laterality, derailed site, and histology of female breast cancer, California, 1988-1999 / Sandy L. Kwong -- Surgical treatment of female breast cancer in California / Cyllene R. Morris -- Breast cancer survival in the San Francisco Bay Area / Cynthia O'Malley, Gem Le -- Technical notes.

Burden of breast cancer in developing and developed countries -- Genetics of breast cancer in women of African Descent: an overview -- Biology of breast cancer: molecular and pathologic features of ductal neoplasia of the breast: racial considerations -- Screening and early detection of breast cancer in women in Africa and the Middle East -- Breast cancer at diagnosis in women of Africa and the Middle East -- Breast cancer aggressiveness in women of African descent -- Radiotherapy of breast cancer -- Adjuvant therapy of breast cancer -- Endocrine therapy of breast cancer -- Palliative care for breast cancer in the African-American population -- Outcome of African American women with breast cancer in cooperative group clinical trials -- Traditional medicine in breast cancer management with a focus on the Chinese integrative approach -- Impact of culture, education and socio-economic status -- Barriers to successful management of breast cancer.

Breast tissue banking: collection, handling, storage, and release of tissue for breast cancer research / Linda Snell and Peter H. Watson -- Frozen biopsy collection and storage: frozen biopsy samples / Russell Leek -- Serial biopsies/fine-needle aspirates and their assessment / Irene Boeddinghaus and Stephen R.D. Johnson -- Breast tissue microarrays / Robert J. Springall and Cheryl E. Gillett -- Preparation of tumor homogenates for subsequent preparation of cytosols, membrane fractions, RNA, and DNA / Naomi Robertson and Russell Leek -- Isolation of RNA from tumor samples: single-step guanidinium acid-phenol method / Naomi Robertson and Russell Leek -- Isolation of DNA from tumor samples / Naomi Robertson and Russell Leek -- Laser-assisted microdissection and isolation of DNA and RNA / Ulrich Lehmann and Hans Kreipe --Fluorescence in situ hybridization and comparative genomic hybridization / Patricia Gorman and Rebecca Roylance -- Fluorescence in situ hybridization assessment of c-myc gene amplification in breast tumor tissues / Jan K. Blancato, Mary Steele Williams, and Robert B. Dickson -- Detection of HER2 gene amplification by fluorescence in situ hybridization in breast cancer / John M.S. Bartlett, and Amanda Forsyth -- In situ hybridization combined with immunohistochemistry to localize gene expression / Rosemary Jeffery, Toby Hunt, and Richard Poulsom -- Quantitation of RNA by ribonuclease protection assay / John W. Moore -- Identification of steroid hormone-regulated genes in breast cancer / Bruce R. Westley and Felicity E.B. May -- Sequencing of the tumor suppressor gene TP 53 / Barbro Linderholm, Torbjörn Norberg, and Jonas Bergh -- Expression profiling using cDNA microarrays / Chris Jones ... [et al.] -- Gene expression analysis using filter cDNA microarrays / Peter Simpson ... [et al.] --Immunohistochemistry / Cheryl E. Gillett -- Detection of aberrant glycosylation in breast cancer using lectin histochemistry / Tracey M. Carter and Susan A. Brooks -- SDS-PAGE and western blotting to detect proteins and glycoproteins of interest in breast cancer research / Chloe Osborne and Susan A. Brooks -- Breast cancer proteomics using two-dimensional electrophoresis: studying the breast cancer proteome / Miriam V. Dwek and Sarah L. Rawlings -- Procedures for the quantitative protein determination of urokinase and its inhibitor PAI-1 in human breast cancer tissue extracts using ELISA / Manfred Schmitt ... [et al.] --Methods to analyze the effects of the urokinase system on cancer cell adhesion, proliferation, migration, and signal transduction events / Ute Reuning ... [et al.] -- Phospho-specific antibodies as a tool to study in vivo regulation of BRCA1 after DNA damage / Kum Kum Khanna, Magtouf Gatei, and Gordon Tribbick -- Models of hormone resistance in vitro and in vivo / Jennifer MacGregor Schafer and V. Craig Jordan -- Generation of genetically modified embryonic stem cells for the development of knockout mouse animal model systems / Stephen D. Robinson, Stephen Wilson, and Kairbaan M. Hodivala-Dilke -- In vivo xenograft models of breast cancer metastatsis / Ursula Valentiner, Susan A. Brooks, and Udo Schumacher -- Neoadjuvant endocrine therapy models / Juliette Murray, William R. Miller, and J. Michael Dixon -- Primary mouse endothelial cell culture for assays of angiogenesis / Louise E. Reynolds and Kairbaan M. Hodivala-Dilke.Traditional and established indicators of prognosis and treatment success / Derek E. Roskell and Ian D. Buley -- Sentinel lymph node biopsy in breast cancer / Celia Chao and Kelly M. McMasters -- Pathological evaluation of axillary sentinel lymph nodes in breast cancer / Michael Z. Gilcrease and Aysegul Sahin -- Measurement of estrogen receptor status by immunocytochemistry in paraffin wax sections / Bharat Jasani ... [et al.] -- Markers of apoptosis / Falzul H. Sarkar and Yiwei Li -- Quantitative angiogenesis in breast cancer / Stephen B. Fox --

Part I. Prevention -- Risk Factors / Polly A. Newcomb and Karen J. Wernli -- Lifestyle Factors and Risk of Breast Cancer: A Review of Randomized Trial Findings / Garnet L. Anderson -- Breast Cancer Chemoprevention / Mary B. Daly -- Surgical Management of Inherited Susceptibility to Breast Cancer / Francis Freisinger and Susan M. Domchek -- Part II. Early Detection -- Clinical Breast Examination and Breast Self-Examination / William H. Goodson -- Mammography / Barbara C. Cavanaugh and Sorcha McNally -- Current Status and Future Prospects in Breast Carcinoma of Positron Emission Tomography / Sandip Basu, Joshua I. Rosenbaum and Abass Alavi -- Breast MRI / Barbara C. Cavanaugh and Sorcha McNally -- Genetic and Molecular Approaches to Imaging Breast Cancer / Eric Wickstrom and Mathew L. Thakur -- Intraductal Approaches: Nipple Aspirate Fluid to Assist in Breast Cancer Detection / Edward R. Sauter -- Intraductal Approaches: Mammary Ductoscopy and Ductal Lavage to Assist in the Diagnosis of Breast Cancer / William C. Dooley -- Blood Markers / Mark W. Duncan -- Circulating Tumor Cells in Breast Cancer / Michail Ignatiadis and Dimitris Mavroudis.

Breast cancer: an overview -- Regulatory issues -- Quality control -- Technical considerations -- Screening mammography -- Diagnostic mammography and problem solving -- Breast ultrasound -- Magnetic resonance imaging -- Skin -- Nipple-areolar complex -- Major subareolar ducts -- Terminal ducts -- Lobules -- Stroma -- The altered breast -- The male breast -- Interventional procedures -- Documentation and the mammographic report -- Mammography audit.

Breast anatomy and basic histology, physiology, and pathology -- A pathologist's overview of the pathology of breast disease / Joseph Rabban -- Epidemiology, etiology, risk factors, and survival from breast cancer -- Screening for breast cancer -- Radiation risk -- Staging breast cancer -- Ductal carcinoma in situ and early-stage breast cancer: detection, diagnosis, and prognostic indicators -- Mammography: equipment and basic physics -- Quality assurance and quality control / Debra Deibel -- Mammographic positioning -- A systematic approach to breast imaging -- Mammography and the normal breast -- Interpreting the mammogram -- Benign lesions -- Probably benign findings appropriately managed with short-interval follow-up --Suspicious lesions and lesions with a high probability of malignancy -- Breast ultrasound -- The altered breast: pregnancy, lactation, abscess, post biopsy changes, mastectomy, radiation, and implants -- The male breast -- Magnetic resonance imaging of the breast / Carol A. Hulka and Daniel B. Kopans -- Evaluating women with lumps, thickening, discharge or pain: imaging women with signs or symptoms that might indicate breast cancer -- Image sequencing: problems and solutions in breast evaluation -- Histological, pathological and imaging correlation -- Interventional procedures in the breast -- The breast imaging report: data management and the breast imaging audit -- The medical-legal problem and breast imaging -- Digital mammography -- Digital breast tomosynthesis -- Cytopathology.

Anatomy and physiologic morphology -- Inflammatory and reactive tumors -- Specific infections -- Benign papillary tumors -- Myoepithelial neoplasms -- Adenosis and microglandular adenosis -- Fibroepithelial neoplasms -- Ductal hyperplasia and intraductal carcinoma -- Invasive duct carcinoma -- Tubular carcinoma -- Papillary carcinoma -- Medullary carcinoma -- Carcinoma with metaplasia -- Squamous carcinoma -- Mucinous carcinoma -- Apocrine carcinoma -- Adenoid cystic carcinoma -- Secretory carcinoma -- Cystic hypersecretory carcinoma -- Other special types of invasive duct carcinoma -- Lobular carcinoma in situ and atypical lobular hyperplasia -- Invasive lobular carcinoma -- Mesenchymal neoplasms -- Lymphoid and hematopoietic tumors -- Metastases in the breast from nonmammary malignant neoplasms -- Pathologic effects of therapy -- Breast lesions in men and children -- Pathologic changes associated with needling procedures -- Needle core biopsy specimens of the breast: pathologic processing, examination, and reporting thereof / Syed A. Hoda -- Techniques for imaging-guided needle core biopsy / D. David Dershaw -- Impact of percutaneous image-guided core biopsy on the clinical management of breast disease / Laura Liberman.

Pt. 1. Fundamentals -- pt. 2. Biologic principles -- pt. 3. Initial evaluation of the patient -- pt. 4. Common presenting complaints and concerns -- pt. 5. Diagnostic techniques -- pt. 6. Breast cancer overview -- pt. 7. Breast surgery : management of the primary tumor -- pt. 8. Breast surgery : sentinel node biopsy and axillary dissection -- pt. 9. Breast surgery : special issues -- pt. 10. Cytology and pathology -- pt. 11. Systemic therapy for breast cancer -- pt. 12. Radiation therapy of the breast -- pt. 13. The breast cancer survivor.

1. Growth and organ development / T.J. Cole -- 2. Nutrient transfer: mammary gland regulation / S.L. Kelleher, B. Lönnerdal -- 3. Micronutrient transfer: infant absorption / B. Lönnerdal, S. L. Kelleher -- 4. Developmental aspects of the mucosal immune system ... / P.L. Ogra -- 5. Infant feeding and growth / K.G. Dewey -- 6. Intestinal flora / C. Kunz, S. Kuntz, S. Rudloff -- 7. Transenteric signalling: mammary messages or white noise / L.T. Weaver -- 8. Immune function / L.Å. Hanson, ... et al. -- 9. Flavour programming during breast-feeding / J.A. Mennella -- 10. Methodological challenges in studying long-term effectors of breast-feeding / M.S. Kramer -- 11. Long term effects of early postnatal diet on adult health / S.E. Ozanne -- 12. Protective effect of breast-feeding against obesity in childhood ... / S. Arenz, R. Von Kries -- 13. Breast-feeding influences on later life - cardiovascular disease / D.A. Leon, G. Ronalds -- 14. Do infants who are breast-fed have an altered risk of developing cancer / R. Martin, G. Davey Smith, D.Gunnell --15. Effects of breast-feeding on cognitive function / K.F. Michaelsen, L. Lauritzen, E L. Mortensen -- 16. Developmental origins of osteoporotic fracture / C. Cooper, ... et al. -- 17. Long-term effects of breast-feeding on asthma and atopic disease / W.H. Oddy -- 18. Evolution of human lactation and complementary feeding: Implications for understanding contemporary cross-cultural variation / D.W. Sellen -- 19. Macy-György prize lecture: my milky way / L.Å. Hanson -- 20. Exclusive breast-feeding and HIV infection / L. Kasonka, S. Filteau, and The Breast-Feeding and Postpartum Health Project Team -- 21. Breast-feeding practices in relation to HIV in India / A.V. Shankar -- 22. Breast-feeding and HIV-1 infection: maternal health / P.A. Otieno -- 23. Early breast-feeding cessation and infant mortality in low-income countries: workshop summary / K.B. Simondon -- 24. Measuring trace immune factors in human milk: workshop summary / S. Filteau -- 25. Abstracts of poster presentations.

Central regulation of breathing -- Neurogeneration and neuroprotection -- Brain functions in health and disease -- Brain functions by the Dipole Tracing method.

Executive summary -- Report of the working-group meeting / Christos Louis and Bart G.J. Knols -- Review of previous applications of genetics to vector control / Chris F. Curtis -- Genomics and expected benefits for vector entomology / Christos Louis -- Genetic approaches for malaria control / Marcelo Jacobs-Lorena -- Current thoughts about the integration of field and laboratory sciences in genetic control of disease vectors / Thomas W. Scott -- Genetic approaches in Aedes aegypti for control of dengue: an overview / Kenneth Olson .... [et al.] -- Malaria and dengue vector biology and control in West and Central Africa / Didier Fontenille and Pierre Carnevale -- Malaria and dengue vector biology and control in Southern and Eastern Africa / Maureen Coetzee -- Malaria and dengue vector biology and control in Southeast Asia / Pattamaporn Kittayapong -- Malaria and dengue vector biology and control in Latin America / Mario H. Rodriguez -- Transition from the laboratory to the field and effective interplay / Christos Louis -- Evaluation of drive mechanisms (including transgenes and drivers) in different environmental conditions and genetic backgrounds / Anthony A. James ... [et al.] -- Tools for monitoring the genetic structure and stability of mosquito populations / Gregory C. Lanzaro, Sergey Nuzhdin and Frederic Tripet -- What are relevant assays for refractoriness / George K. Christophides ... [et al.] -- Fitness studies: developing a consensus methodology / Thomas W. Scott ... [et al.] --Mosquito mating behaviour / Willem Takken ... [et al.] -- Pathogen evolution issues in genetically modified mosquito vector strategies / Mario H. Rodriquez -- Models to investigate some issues regarding the feasibility of driving refractoriness genes into mosquito vector populations / Chris F. Curtis -- Identification and characterization of field sites for genetic control of disease vectors / Bart G.J. Knols and Hervé Bossin -- Application of genetically modified mosquitoes in national vector control programmes: thoughts on integrated control / Abraham Mnzava ... [et al.] -- Entomological correlates of epidemiological impacts: how do we know it is working? / Andrew Githeko -- Ethical, legal and social issues in the use of genetically modified vectors for disease control / Yeya T. Touré and Lucien Manga.

Hospital-based pain care for infants and children / Brenda C. McClain -- Treatment of acute and chronic pain in the outpatient setting / Neil L. Schechter -- Pain and pain relief in pediatric end-of-life care / John J. Collins and Gerri Frager -- Residential treatment settings for adolescent chronic pain management : rationale, development and evidence / Christopher Eccleston, Hannah Connell, and Nicola Carmichael -- Managing pediatric pain at school / Ronald T. Brown -- Efficacy of complementary and alternative medicine approaches for pediatric pain : state of the science / Jennie C.I. Tsao, Marcia Meldrum, and Lonnie K. Zeltzer -- Technology in pediatric pain management / Patrick J. McGrath, Carolyn Watters, and Erin Moon -- Developing pain services around the world / G. Allen Finley and Paula A. Forgeron -- Knowledge translation and pain management / Shannon Scott-Findlay and Carole A. Estabrooks.

Introduction to an unregarded killer -- The history of influenza -- Pandemic geographies -- The human cost -- Impacts and responses -- Cultural dimensions -- Repercussions -- Possible futures.

Microorganisms and microbiology -- An overview of microbial life -- Macromolecules -- Cell structure/function -- Nutrition, laboratory culture, and metabolism of microorganisms -- Microbial growth -- Essentials of molecular biology -- Metabolic regulation -- Essentials of virology -- Bacterial genetics -- Microbial evolution and systematics -- Prokaryotic diversity : the bacteria -- Prokaryotic diversity : the archaea -- Eukaryotic cell biology and eukaryotic microorganisms -- Microbial genomics -- Viral diversity -- Metabolic diversity -- Methods in microbial ecology -- Microbial ecology -- Microbial growth control -- Microbial interactions with humans -- Essentials of immunology -- Molecular immunology -- Diagnostic microbiology and immunology -- Epidemiology -- Person-to-person microbial diseases -- Animal-transmitted, arthropod-transmitted, and soilborne microbial diseases -- Wastewater treatment, water purification, and waterborne microbial diseases -- Food preservation and foodborne microbial diseases -- Industrial microbiology -- Genetic engineering and biotechnology.

The mysteries of heart attacks -- The case for plaque rupture -- The case against plaque rupture -- Learning by doing -- The plaque rupture consensus -- Rupture therapeutics -- Therapeutic ruptures -- Fear and unpredictability -- Surgical ambition and fear -- Suffering cerebrums -- Deliriogenic personalities -- The case of the missing complications -- Selective inattention -- The cerebral complications of coronary artery bypass surgery -- A taxonomy of inattention -- Competition's complications.

Occupational asthma: a special environmental interaction / Nicholas J. Kenyon, Brian M. Morrissey, and Timothy E. Albertson -- Anesthesia for patients with asthma / Dennis L. Fung -- How recreational drugs affect asthma / Timothy E. Albertson, Steve Offerman, and Nicholas J. Kenyon -- Self-management in asthma: empowering the patient / Arvind Kumar and M. Eric Gershwin -- The challenge of asthma in minority populations / Albin B. Leong -- Asthma and the law / Charles Bond.The origins and characteristics of asthma / Russell J. Hopp and Robert G. Townley -- Diagnosing allergic asthma / Gerald L. Klein -- How the pulmonary function laboratory contributes to the management of the patient with asthma / Richard E. Kanner and Theodore G. Liou -- Treatment of asthma in children / Christopher Chang -- Adult-onset asthma / Samuel Louie ... [et al.] -- The patient with asthma in the emergency department / Donna Kinser -- Severe asthma: from ICU to discharge / Brian M. Morrissey, Nicholas J. Kenyon, and Timothy E. Albertson -- Complementary/alternative therapies in asthma / Andrea Borchers, Carl L. Keen, and M. Eric Gershwin --The pregnant patient with asthma / Arif M. Seyal -- Infectious and environmental triggers of asthma / Laurel J. Gershwin -- Exercise-induced asthma: sports and athletes / Rahmat Afrasiabi -- How can foods, additives, and drugs affect the patient with asthma? / Suzanne S. Teuber -- Allergic bronchopulmonary aspergillosis: an evolving challenge in asthma / Brian M. Morrissey and Samuel Louie --

Smallpox : eradicating an ancient scourge -- Oral rehydration salts : a miracle cure -- Mental health : unlocking the asylum doors -- The tobacco trap : fighting back -- AIDS : fear, stigma, and hope -- Tuberculosis : complacency kills -- Outbreak : the world's emergency room.

Introduction -- Attracting visionary and courageous leaders -- Building a place for caring, healing and learning -- Holding steady when the earth gives way -- Fighting back against epidemics -- Saving lives and making them better with all the latest care -- Pioneering new methods of surgery -- Forging a strong partnership with physicians -- Setting the standard for nursing care -- Fulfilling a long commitment to children and families -- Remembering the human side of health care -- Keeping the community healthy -- Reaching out to people in their homes -- Unlocking the mysteries of the human body -- Inspiring the loyalty of donors and volunteers -- Teaming up with business and industry -- Managing change with skill and care -- Looking ahead -- Marking milestones in the history of health care.

What is bullying? /Cheryl E. Sanders --Who are the victims? /Xin Ma --Atheoretical review of bullying: can it be eliminated? /Adrienne Nishina --In the looking glass: a reciprocal effect model elucidating the complex nature of bullying, psychological determinants, and the central role of self-concept /Herbert W. Marsh...[et al.] -- Thebully in the family: family influences on bullying /James R. Holmes,Heather A. Holmes-Lonergan --Peer influences /Helen Cowie --Schools and bullying: school factors related to bullying and school-based bullying interventions /Allison Ann Payne,Denise C. Gottfredson --Bullying during middle school years /A.D. Pellegrini --Evaluating curriculum-based intervention programs: an examination of preschool, primary, and elementary school intervention programs /Faith L. Samples --Research based interventions on bullying /Jaana Juvonen,Sandra Graham.

Macroscopical characters of the medicinal species of Bupleurum and their distribution in China / Sheng-Li Pan and Yun Kang -- Microscopical characters of the medicinal species of Bupleurum in China / Sheng-Li Pan -- Chromosomes of Bupleurum l. especially for the classification and cross-breeding of B. falcatum L. sensu lato / Shigeki Ohta ... [et al.] -- Cultivation of Bupleurum falcatum in Japan / Osamu Iida -- Distribution of saikosaponins of Bupleurum falcatum and variation of its contents in plant organs by environmental factors / Nak-Sul Seong, Hae-Gon Chung and Kwan-Su Kim -- Main chemical constituents of Bupleurum genus / Sheng-Li Pan -- The chemistry and biological activity of the genus Bupleurum in Spain / Alejandro F. Barrero ... [et al.] -- The chemistry and biological activity of the genus Bupleurum in Italy / Luisa Pistelli --The pharmacological activity of Chinese "chaihu": the root of Bupleurum species / Xiao-Min Du, Hui Xie and Yun Kang -- Pharmacological activity of saikosaponins / Byung-Zun Ahn and Dai-Eun Sok -- Mitogenic substances of Bupleuri radix / Naohito Ohno and Toshiro Yadomae -- Clinical applications of prescriptions containing Bupleurum root / Bai-Can Yang and Jun Wang -- Anti-hepatofibrotic effect of xiao-chaihu-tang (sho-saiko-to) / Ichiro Shimizu -- Preventive effects of sho-saiko-to against septic shock symptoms / Shuhei Sakaguchi -- Patents containing Bupleurum.

"... provides an established, recognized, authoritative and comprehensive source on medicinal chemistry and drug discovery and development. This flagship reference for medicinal chemists and pharmaceutical professions has been thoroughly updated and expanded across 8 volumes to incorporate the entire process of drug development (preclinical testing, clinical trials, etc.) alongside the traditional strengths in medicinal chemistry and drug discovery"--Provided by publisher.

Visualization -- Angle of approach -- Creating a stable construct -- Understanding and recognizing pathology -- The tough stuff -- Exposing the hidden arthroscopic landmarks -- Insurmountable problems -- Gaining speed and tricks of the trade -- Order of steps -- Rotator cuff tear patterns -- Postoperative rehabilitation -- Operating room set-up -- Instability -- SLAP repair -- Subacromial procedures (non-cuff) -- Stiffness -- Rotator cuff -- Biceps -- Tricks and tips -- Assorted conditions -- The future.

1. Genetic variability provides the biochemical basis for our individuality, including differences in our susceptibility to many common diseases -- 2. Making the most of family history information, single gene disorders and Mendelian patterns of inheritance, and when to refer to a genetic specialist -- 3. Types of genetic tests and issues associated with the interpretation of their results -- 4. Toward the safer and more effective use of prescription drugs: pharmacogenetics -- 5. Taking a personalized medicine approach to breast and colon cancer -- 6. Personalized risk assessments and treatments for complex cardiovascular disease -- 7. Other multifactorial disorders for which genetic/genomic testing is providing insights -- Epilogue and list of resources.