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  • 2015
    Specific information in this year's Alzheimer's Disease Facts and Figures includes: Proposed criteria and guidelines for diagnosing Alzheimer's disease from the National Institute on Aging and the Alzheimer's Association; Overall number of Americans with Alzheimer's disease nationally and for each state; Proportion of women and men with Alzheimer's and other dementias; Estimates of lifetime risk for developing Alzheimer's disease; Number of deaths due to Alzheimer's disease nationally and for each state, and death rates by age; Number of family caregivers, hours of care provided, economic value of unpaid care nationally and for each state, and the impact of caregiving on caregivers; Use and costs of health care, long-term care and hospice care for people with Alzheimer's disease and other dementias; Challenges surrounding the disclosure of an Alzheimer's disease diagnosis to individuals with the disease. The Appendices detail sources and methods used to derive data in this report. This report frequently cites statistics that apply to all individuals with dementia. When possible, specific information about individuals with Alzheimer's disease is provided; in other cases, the reference may be a more general one of individuals with "Alzheimer's disease and other dementias."
  • 2014
    2014 Alzheimer's Disease Facts and Figures is a statistical resource for U.S. data related to Alzheimer's disease, the most common type of dementia, as well as other dementias. Background and context for interpretation of the data are contained in the Overview. This information includes definitions of the various types of dementia and a summary of current knowledge about Alzheimer's disease. Additional sections address prevalence, mortality and morbidity, caregiving and use and costs of care and services. The Special Report discusses women and Alzheimer's disease.
  • Rosado-de-Christenson, Melissa L.
    Status: Not Checked OutLane Catalog Record
  • de Christenson, Melissa R.
    Status: Not Checked OutLane Catalog Record
  • de Christenson, Melissa R.
    Status: Not Checked OutLane Catalog Record
  • 2014 CRCnetBASE
    Gossage, James A.; Burnand, Kevin G.; Modarai, Bijan; Sahai, Arun; Worth, Richard.
    General and colorectal -- Upper gastrointestinal -- Breast and endocrine -- Vascular -- Urology -- Orthopaedic -- Ear, nose, and throat -- Neurosurgery -- Anaesthesia -- Postoperative complications.
  • 2010 ProQuest Safari
    Kachinske, Timothy; Kachinske, Judith.
    Getting started as a Grant writer -- Finding and securing a Grant-writing position -- Expertise -- Research -- Managing relationships -- Writing -- Organizing information -- Queries and short proposals -- Proposals for projects, programs, or bricks and mortar -- Proposals for endowment support -- Federal Grants -- Managing Grant awards.
  • v. 1-3, 2013.
    Huang, Kun; Johnston, Calvin; McMurrich, Jamie; Woodford, Curtis; Yao, Christopher; Yin, Penny.
    Status: Not Checked OutLane Catalog Record
    V 1. 2013 essential med notes clinical handbook; V. 2. Clinical handbook, 2013 essential med notes; V. 3. Stat notes, 2013 essential med notes.
  • 2012
    Cooley, Denton A.
    Status: Not Checked OutLane Catalog Record
    Pioneering surgeon Dr. Denton Cooley performed his first human heart transplant in 1968 and astounded the world in 1969 when he was the first surgeon to successfully implant a totally artificial heart in a human being. Over the course of his career, Cooley and his associates have performed thousands of open heart operations and have been forerunners in implementing new surgical procedures. Of all his achievements, however, Cooley is most proud of the Texas Heart Institute, which he founded in 1962 with a mission to use education, research, and improved patient care to decrease the devastating effects of cardiovascular disease. In his new memoir, 100,000 Hearts, Cooley tells about his childhood in Houston and his experiences as a basketball scholarship recipient at the University of Texas. After medical school at the University of Texas Medical Branch in Galveston and Johns Hopkins, Cooley served in the Army Medical Corps. While at Johns Hopkins, Cooley assisted in a groundbreaking operation to correct an infant's congenital heart defect, which inspired him to specialize in heart surgery. Cooley's detailed descriptions of what it was like to be in the operating room at crucial points in medical history offer a fascinating perspective on how far medical science has progressed in just a few decades. Dr. Denton Cooley and the Texas Heart Institute are responsible for much of that progress.
  • 2015
    Forword by David Beckmann -- Executive summary -- Introduction -- Chapter 1. Hunger and health over the life course -- Chapter 2. Partnering for collective impact -- Chapter 3. Unprecendented gains, undeniable challenges: hunger, health, and inequality in developing countries -- Conclusion: A transformational agenda.
  • 2015 ClinicalKey
    Gahart, Betty L.; Nazareno, Adrienne R.; Ortega, Meghan Q.
    General dilution charts -- Format and content of intravenous medications -- Key to abbreviations -- Important IV therapy facts -- Resources -- IV drugs -- Appendix A: Recommendations for the safe use and handling of cytotoxic drugs -- Appendix B: FDA pregnancy categories) -- Appendix C: U.S. Department of Health and Human Services, National Institutes of Health, National Cancer Institute Common Terminology Criteria for adverse events (CTCAE) -- Appendix D: Information for patients receiving immunosuppressive agents -- Appendix E: Recently approved drugs -- Solution compatibility chart.
  • 2014 Ovid
    Karch, Amy Morrison.
    Nursing Process Guidelines -- Patient Safety and Medication Administration -- Pharmacologic Classes -- Alphabetical Listing of Drugs by Generic Name.
  • 2007 ProQuest Safari
    Joyce, Jerry; Moon, Marianne.
    About this book -- Working in Office -- Common tasks in Office -- Viewing and editing text in Word -- Formatting in Word -- Working with special content in Word -- Working in Excel -- Analyzing and presenting data in Excel -- Creating a PowerPoint presentation -- Presenting a PowerPoint slide show -- Working with messages in Outlook -- Organizing with Outlook -- Creating a publication in Publisher -- Working in Access -- Exchanging information among Office programs -- Customizing and securing Office.
  • 2007 Ovid
    Kirsch, Jeffrey R.; Sibell, David M.
  • 2005-06 Ovid
    Bartlett, John G.
  • 2006
    Taylor, George Jesse.
    Status: Not Checked OutLane Catalog Record
    How to interpret ECGs -- Baseline data -- Morphologic changes in P, QRS, ST, and T -- 150 practice ECGs -- Interpretation and comments.
  • 1980-
    Bell, Roy.
    Status: Not Checked OutLane Catalog Record
  • 2011 ProQuest Safari
    Teetor, Paul.
  • 2014
    Hochman, Michael E.
    Status: Not Checked OutLane Catalog Record
    Sect. 1: Preventive medicine -- Preventing diabetes: the diabetes prevention program -- A comparison of different dieting strategies -- Aspirin for the primary prevention of cardiovascular disease: the physician's health study and the women's health study -- Postmenopausal hormone therapy: the women's health initiative -- The European randomized study of screening for prostate cancer (ERSPC) -- The cochrane review of screening mammography -- The human papillomavirus vaccine: the future II trial -- Sect. 2: Internal medicine -- Arrhythmia suppression following myocardial infarction: the CASt trial -- Choosing first-line therapy for hypertension: the ALLHAT trial -- Statins in healthy patients with an elevated c-reactive protein: the JUPITER trial -- Rate control versus rhythm control for atrial fibrillation: the AFFIRM trial -- Lenient versus strict heart rate control for atrial fibrillation: the RACC II trial. -- Beta blockers for systolic heart failure: the MERIT-HF trial -- Initial treatment of stable coronary artery disease: the COURAGE trial -- Treating elevated blood sugar levels in patients with type 2 diabetes: the United Kingdom prospective diabetes study (UKPDS) -- Intensive versus conservative blood sugar for patients with type 2 diabetes: the ACCORD trial -- The African American heart failure trial (A-HeFT) -- Early versus delayed antiretroviral therapy for patients with HIV: the NA-ACCORD study -- Early versus late initiation of dialysis: the IDEAL trial -- Early goal-directed therapy in sepsis -- Red cell transfusion in critically ill patients: the TRICC trial -- Pulmonary artery catheters in critically ill patients -- Step-up versus step-down therapy for dyspepsia: the DIAMOND trial -- Opioids for chronic noncancer pain -- Sect. 3: Surgery -- Perioperative beta blockers in noncardiac surgery: the POISE trial -- Cardiac stents versus coronary artery bypass surgery for severe coronary artery disease: the SYNTAX trial -- Carotid endarterectomy for asymptomatic carotid stenosis: the ACST trial -- A trial of arthroscopic knee surgery -- Surgery versus rehabilitation for chronic low back pain: the MRC spine stabilization trial -- Mastectomy versus lumpectomy for invasive breast cancer: the B-06 trial -- Long-term impact of bariatric surgery: the Swedish obese subjects study -- Sect. 4: Obstetrics -- The Canadian multicenter post-term pregnancy trial (CMPPT) -- Antepartum glucocorticoids in premature labor -- Sect. 5: Pediatrics -- Treatment of acute otitis media in children -- A trial of early ear tube placement in children with persistent otitis media -- Inhaled corticosteroids for mild persistent asthma: the START trial -- The multimodal treatment study of children with attention deficit/hyperactivity disorder (MTA) -- Measles, mumps, and rubella vaccination and autism -- Sect. 6: Radiology -- Magnetic resonance imaging for low back pain -- Screening for coronary artery disease in asymptomatic patients with diabetes: the DIAD study -- Diagnosing acute pulmonary embolism: the Christopher study -- Identifying children with low-risk head injuries who do not require computed tomography -- Sect. 7: Neurology and psychiatry -- Thrombolysis 3 to 4.5 hours after an acute ischemic stroke: the ECASS III trial -- Initial treatment of depression -- Behavioral versus pharmacological treatment for insomnia in the elderly -- Sect. 8: Systems-based practice -- The group health medical home demonstration -- A program to improve care coordination at hospital discharge: project RED -- Reducing catheter-related blood stream infections in the intensive care unit: the keystone ICU project -- Early palliative care in non-small-cell lung cancer -- Directly observed therapy for the treatment of tuberculosis in Baltimore.
  • 2015 Springer
    Cho, Z.-H.
    The inaugural publication of the 7.0 Tesla MRI Brain Atlas: In-vivo Atlas with Cryomacrotome Correlation in 2010 provided readers with a spectacular source of ultra-high resolution images revealing a wealth of details of the brainstem and midbrain structures. This second edition contributes additional knowledge gained as a result of technologic advances and recent research. To facilitate identification and comparison of brain structures and anatomy, a detailed coordination matrix is featured in each image. Updated axial, sagittal, and coronal images are also included. This state-of-the-art and user-friendly reference will provide researchers and clinicians with important new perspectives.
  • 2010 Springer
    Cho, Z.-H.
  • 2015 Springer
    Cho, Z.-H.
    The introduction of techniques that permit visualization of the human nervous system is one of the foremost advances in neuroscience and brain-related research. Among the most recent significant developments in this respect are ultra-high field MRI and the image post-processing technique known as track density imaging (TDI). It is these techniques (including super-resolution TDI) which represent the two major components of 7.0 Tesla MRI ? Brain White Matter Atlas. This second edition of the atlas has been revised and updated to fully reflect current application of these technological advancements in order to visualize the nervous system and the brain with the finest resolution and sensitivity. Exquisitely detailed color images offer neuroscientists, neurologists, and neurosurgeons a superb resource that will be of value both for the purpose of research and for the treatment of common brain diseases such as Alzheimer's disease and multiple sclerosis.
  • 2012 Springer
    Schüttler, Jürgen.
  • 2013 Springer
    Bower, James M.
  • 2013 Springer
    Burke, Thomas W.; Rodriguez, M. Alma; Walters, Ronald S.
    Introduction / M. Alma Rodriguez -- History of MD Anderson's tumor registry / Sarah H. Taylor -- Statistical methods / Geoffrey G. Giacco, Sarah H. Taylor and Kenneth R. Hess -- Breast cancer / Aman U. Buzdar ... [et al.] -- Prostate cancer / Deborah A. Kuban ... [et al.] -- Non-small cell lung cancer / Ritsuko Komaki, Anne S. Tsao, and Reza J. Mehran -- Small cell lung cancer / Frank V. Fossella -- Colon cancer / Cathy Eng, Patrick Lynch, and John Skibber -- Ovarian cancer / Robert L. Coleman and David M. Gershenson -- Cervical cancer / Patricia J. Eifel and Charles Levenback -- Endometrial cancer / Thomas Burke ... [et al.] -- Pancreatic cancer (exocrine) / Jason Fleming ... [et al.] -- Kidney cancer / Scott E. Delacroix Jr. ... [et al.] -- Bladder cancer / Robert S. Svatek ... [et al.] -- Cutaneous melanoma / Jeffrey E. Gershenwald, Geoffrey G. Giacco, and Jeffrey E. Lee -- Liver cancer / Evan S. Glazer and Steven A. Curley -- Esophageal cancer / Linus Ho ... [et al.] -- Gastric cancer / Alexandria T. Phan and Paul F. Mansfield -- Acute myeloid leukemia / Emil J. Freireich -- Chronic lymphocytic leukemia/small lymphocytic lymphoma / Apostolia-Maria Tsimberidou and Michael J. Keating -- Hodgkin lymphoma / Michelle Fanale ... [et al.] -- Non-hodgkin indolent B-cell lymphoma / Sattva S. Neelapu -- Non-hodgkin aggressive B-cell lymphoma / M. Alma Rodriguez -- Multiple myeloma / Donna Weber and Raymond Alexanian -- Head and neck cancer / Ehab Hanna ... [et al.] -- Thyroid cancer / Steven I. Sherman, Nancy Perrier, and Gary L. Clayman -- Soft tissue sarcomas / Vinod Ravi, Raphael Pollock, and Shreyaskumar R. Patel -- Sarcomas of bone / Valerae Lewis.
  • 2010 Springer
    Borea, Pier Andrea.
  • Ovid
  • 2008
    Lebet, Ruth M.; Verger, Judy Trivits.
    Status: Not Checked OutLane Catalog Record
  • 2005- HighWire
  • v. 1-3, 1992-93.
    Status: Not Checked OutLane Catalog Record
    Vol. 1 Contains standards for equipment, decontamination of medica by steam, ethylene oxide, gamma radiation, and electron beam radiation. -- Vol. 2 Contains standards for biomedical equipment. -- Vol. 3 Contains all documents developed under the auspices of the Renal Disease and Detoxification Committee and Hemodialyzer Reuse Submittee.
  • 2008 ClinicalKey
    Fisk, John R.; Hsu, John D.; Michael, John W.
    Also available: Print – 2008
  • v. 1-, 2011- Springer
  • 2001 CRCnetBASE
    Stahl, Dean; De Sola, Ralph; Kerchelich, Karen.
  • 2010
    Cantillon, Peter; Wood, Diana.
    Status: Not Checked OutLane Catalog Record
    Applying educational theory in practice / David M. Kaufman -- Course design / John Bligh and Julie Brice -- Collaborative learning / Diana Wood -- Evaluation / Jillian Morrison -- Teaching large groups / Peter Cantillon -- Teaching small groups / David Jaques -- Feedback in medical education : skills for improving learner performance / Joan Sargeant and Karen Mann -- Learning and teaching in the clinical environment / John Spencer -- Written assessment / Lambert W.T. Schuwirth and Cees P.M. van der Vleuten -- Skill-based assessment / Val Wass -- Work-based assessment / John Norcini and Eric Holmboe -- Direct obvservation tools for workplace-based assessment / Peter Cantillon and Diana Wood -- Learning environment / Jill Thistlethwaite -- Creating teaching materials / Jean Ker and Anne Hesketh -- Learning and teaching professionalism / Sylvia R. Cruess and Richard L. Cruess -- Making it all happen : faculty development for busy teachers / Yvonne Steinert -- Supporting students in difficulty / Dason Evans and Jo Brown.
  • 2010 Springer
    Andronikou, Savvas.
  • 2015 ScienceDirect
    Ishikawa, Toshihisa; Schuetz, John D.
    ABC Transporters and Cancer provides invaluable information on the exciting and fast-moving field of cancer research. Here, outstanding and original reviews are presented on a variety of topics. This volume covers ABC transporters and cancer, and is suitable for researchers and students alike.
  • 2006 Springer
    Wong, Dominic W. S.
  • 2013 Springer
    Noffsinger, Edward B.
  • 2008
    Ramnerö, Jonas; Törneke, Niklas.
    Status: Not Checked OutLane Catalog Record
    Topographical aspects of behavior -- Observing behavior: when, where, and how much? -- Knowing your ABCs -- Learning by association: respondent conditioning -- Learning by consequences: operant conditioning -- Operant conditioning: stimulus control -- Learning by relational framing: language and cognition -- Applying your ABCs -- Functional knowledge -- Dialogue toward change -- Principles and practices -- Principles of treatment: one -- Principles of treatment: two.
  • 2013 Springer
    El-Baz, Ayman S.; Saba, Luca; Suri, Jasjit S.
    Covers novel, state-of-the-art strategies in engineering and clinical analysis. Explores approaches for analyzing abdominal imaging, including lung, mediastinum, pleura, liver, kidney and gallbladder. Offers present and future applications as applied to the abdomen and thoracic imaging with the most world-renowned scientists in these fields.
  • 2013 Springer
    Hamm, Bernd; Ros, Pablo R.
    In this book a team of leading experts come together to provide a comprehensive overview of modern imaging of the abdomen and pelvis, with detailed sections on both gastrointestinal and genitourinary imaging. Each chapter has an identical structure and focuses on a particular organ or organ system, allowing the reader to approach the field one topic at a time. Indications for a variety of imaging techniques and examination protocols are clearly described, and the imaging features of normal anatomy and pathologic entities are depicted in an abundance of high-quality images. Care is taken to consider all recent technical developments and new indications, and the diagnostic performance of different imaging modalities is carefully compared. It is anticipated that this book will come to be regarded as the standard work of reference on abdominal and pelvic radiology.
  • 2010 ClinicalKey
    Sahani, Dushyant V.; Samir, Anthony E.
    Plain Radiography of the Abdomen -- Fluoroscopic Study of the Abdomen and Fluoroscopic Contrast Media -- Ultrasound Physics and Instrumentation : A Condensed View -- Abdominal Ultrasound Imaging -- Harmonic Imaging -- Doppler Ultrasound Imaging -- Four-Dimensional Ultrasound Imaging -- Contrast Media and Contrast-Enhanced Ultrasound Evaluation -- Principles of CT Physics -- Instrumentation and Radiation Safety -- Recent Advances -- CT Contrast Media and Principles of Contrast Enhancement -- CT Contrast Media and Principles of Contrast Enhancement -- Principles of MRI Physics -- MRI Instrumentation and Safety -- MRI Pulse Sequences -- MRI Artifacts -- Contrast Media and Contrast-Enhanced MRI -- MR Angiography -- Advanced MRI Applications -- PET/CT Technique and Instrumentation -- Pearls and Pitfalls in PET and PET/CT Interpretation -- PET and PET/CT Clinical Applications -- Principles of 3D Postprocessing -- Advanced Applications in Postprocessing -- Ureteral and Kidney Stones -- Acute Appendicitis -- Hollow Viscus Perforation -- Acute Gastrointestinal Bleeding -- Conventional Imaging of the Stomach and Duodenum -- CT of the Stomach and Duodenum -- Anatomic Variants of the Stomach and Duodenum -- Benign Mucosal Diseases of the Stomach -- Malignant Mucosal Diseases of the Stomach -- Gastric Stromal Tumors -- Gastric Outlet Obstruction -- Abnormal Positions of the Stomach -- Gastric Function Imaging Techniques -- Clinical Applications of Gastric Function Imaging -- Conventional Imaging of the Small Bowel -- CT of the Small Bowel -- Ultrasound Imaging of the Small Bowel -- MRI of the Small Bowel -- Nuclear Medicine Techniques for the Small Bowel -- Small Bowel Obstruction -- Acute Small Bowel Ischemia -- Chronic Small Bowel Ischemia -- Benign Neoplasms and Wall Thickening of the Small Bowel -- Malignant Neoplasms and Wall Thickening of the Small Bowel -- Small Bowel Anomalies and Variants -- Conventional Imaging of the Colon and Rectum -- CT of the Colon and Rectum -- CT Colonography -- Normal Anatomy and Variants of the Colon -- Inflammatory and Infectious Colonic Lesions -- Colonic Vascular Lesions -- Colon Cancer and Screening Strategies -- Imaging of the Postoperative Bowel -- Ultrasonography of the Liver -- CT of the Liver -- MRI of the Liver : From Sequences to Protocol -- Nuclear Imaging of the Liver -- Benign Focal Lesions -- Malignant Focal Lesions -- Fatty Liver Disease -- Cirrhosis -- Hepataic Iron Overload -- Hepatic Storage Disorders -- Hepatitis -- Hepatic Veno-occlusive Diseases -- Cholestatic Hepatic Disorders -- Hepatic Variants -- Imaging of the Pancreas -- Pancreas Normal Variants -- Solid Pancreatic Masses -- Cystic Lesions of the Pancreas -- Imaging of Acute Pancreatitis -- Imaging of Chronic Pancreatitis -- Miscellaneous Pancreatitis -- Miscellaneous Pancreatitis -- Imaging Techniques for the Gallbladder and Bile Ducts -- Gallbladder and Bile Ducts Variants and Anomalies -- Dilated Bile Ducts -- Tumors of the Gallbladder -- Intrahepatic Bile Duct Tumors -- Extrahepatic Bile Duct Tumors -- Diffuse Gallbladder Wall Thickening -- Gallbladder and Bile Duct Functional Imaging -- Focal Splenic Lesions -- Diffuse Splenic Lesions -- Lymph Node Imaging Techniques -- Clinical Role of Lymph Node Imaging -- Conventional Imaging of the Kidneys and Urinary Tract -- CT of the Kidneys and Urinary Tract -- MRI of the Kidneys and Urinary Tract -- Nuclear Imaging of the Kidneys and Urinary Tract -- Benign Focal Renal Lesions -- Malignant Focal Renal Lesions -- Cystic Renal Lesions -- Diffuse Renal Parenchymal Diseases -- Renal Parenchymal Infections -- Renal Vascular Diseases -- Miscellaneous Diffuse Renal Diseases -- Urinary Tract Obstruction -- Benign Ureteral Strictures -- Malignant Ureteral Strictures -- Benign Bladder Lesions -- Malignant Bladder Lesions -- Urinary Tract Anomalies and Variants -- Imaging of Adrenal Glands -- Enlarged Adrenal Glands -- Adrenal Masses -- Imaging of the Prostate and Seminal Vesicles -- Benign Prostatic Hypertrophy -- Benign Focal Prostate Lesions -- Malignant Focal Prostate Lesions -- Seminal Vesicle Lesions -- Imaging of the Penis -- Erectile Dysfunction -- Penile Trauma and Miscellaneous Penile Lesions -- Imaging of the Scrotum -- Benign Testicular Lesions -- Malignant Testicular Lesions -- Imaging of the Urethra -- Imaging of Disorders of the Female Urethra -- Imaging of Disorders of the Male Urethra -- Anatomy of Peritoneum and Retroperitoneum -- Peritoneal Fluid Collections -- Peritonitis and Peritoneal Abscess -- Neoplastic Conditions of the Mesentery and Omentum -- Neoplastic Conditions of the Mesentery and Omentum -- Normal Anatomy of the Abdominal Wall -- Non-neoplastic Conditions of the Abdominal Wall -- Neoplastic Conditions of the Abdominal Wall -- Abdominal Wall Hernias.
  • 2006 HighWire
    Després, Jean-Pierre.
  • 2013 Wiley
    Forsythe, John L. R.; Fung, John Julian; Oniscu, Gabriel C.
    Provides transplant professionals with a step-wise approach to abdominal organ retrieval and bench surgery, illustrating complex anatomical situations and providing practice points and decision algorithms. A go-to reference for transplant surgeons, trainees and fellows, as well as for other professionals involved in abdominal organ transplantation.
  • 2015 Springer
    Ercolani, Giorgio; Pinna, Antonio Daniele.
    1. Immunosuppression in solid organ transplantation -- 2. Infection Complications after Abdominal Organ Transplantation -- 3. National Transplant Network. Donor selection and evaluation criteria -- 4. The safety of donor -- 5. Medical disease after abdominal solid organ transplantation and the risk of solid and hematologic malignant tumor after transplantation) -- 6 Indication and timing -- 7. The donor procurement -- 8. Orthotopic liver transplantation -- 9. Anesthetic and perioperative management for liver transplantation -- 10 Living donor liver transplantation -- 11. Hepatic Acute and chronic rejection -- 12. Postoperative technical complications -- 13. Percutaneous management of biliary and vascular complications -- 14. Re-transplantation (Causes, Outcome) -- 15. Indication and timing -- 16. The donor procurement: Standard technique for procurement in cadaveric donors -- 17. Live donor evaluation -- 18. Living donor nephrectomy -- 19. Renal Transplantation: Surgical technique -- 20. The intraoperative and perioperative management of Kidney transplantation -- 21. Kidney acute and chronic rejection -- 22. Kidney Transplantation: Post-Operative Technical Complications -- 23. Indications and timing -- 24. The donor procurement -- 25 Transplantation -- 26 Abdominal wall transplantation and technique -- 27. Anesthetic and perioperative management for Intestinal transplantation -- 28. Segmental Living-related Small Bowel Transplantation -- 29. Intestinal Acute and Chronic rejection -- 30. Combined Kidney-Liver Transplantation -- 31. Kidney-pancreas Transplantation.
  • 2014 Springer
    Hagopian, Ellen J.; Machi, Junji.
    Abdominal Ultrasound for Surgeons provides a comprehensive guide to the use of ultrasonography in surgical practice of abdominal diseases. The content is divided into three major sections focusing on basic principles of ultrasound, ultrasound anatomy and pathology of the abdomen, and employment of ultrasound of the abdomen in surgical practice. A final section is dedicated to the logistics of incorporating ultrasound into a surgical practice. The first section provides an introduction to the principles of ultrasonography focusing on ultrasound physics, equipment, and instrumentation. A detailed approach to the various scanning methods and image interpretation is demonstrated with illustrations, images, and video. The second section focuses on ultrasound anatomy of the abdomen. Each chapter demonstrates the normal and abnormal ultrasound anatomy of specific abdominal organ or organ systems (abdominal wall, liver, pancreas, biliary, stomach, anorectum, retroperitoneum, vascular) with illustrations and images. The current status and technique of endoscopic ultrasound of the upper and lower gastrointestinal tracks is addressed in this section. The third section provides a state-of-the-art review of the status of each major application of abdominal ultrasound in surgery. Topics range from trauma ultrasound and laparoscopic staging to techniques in ultrasound guidance and three-dimensional targeting. This section provides a comprehensive review of the employment of interventional, intraoperative, laparoscopic, transabdominal and endoscopic ultrasound. The fourth and last section addresses the practice aspects of incorporation of ultrasound into a surgical practice. Abdominal Ultrasound for Surgeons will serve as a very useful resource and guide for surgeons and students with little to some experience in ultrasound, including practicing surgeons, surgical fellows, and surgical residents.
  • 2014 ClinicalKey
    Abeloff, Martin D.; Armitage, James O.; Doroshow, James H.; Kastan, M. B.; Niederhuber, John E.; Tepper, Joel E.
    Part I. Science of Clinical Oncology -- Section A. Biology and Cancer -- 1. Molecular Tools in Cancer Research -- 2. Intracellular Signaling -- 3. The Cellular Microenvironment and Metastases -- 4. Control of the Cell Cycle -- 5. Pathophysiology of Cancer Cell Death -- 6. Cancer Immunology -- 7. Stem Cells, Cell Differentiation, and Cancer -- 8. Vascular and Interstitial Biology of Tumors -- Section B. Genesis of Cancer -- 9. Environmental Factors -- 10. DNA Damage Response Pathways and Cancer -- 11. Viruses and Human Cancer -- 12. Genetic Factors: Hereditary Cancer Predisposition Syndromes -- 13. Genetic and Epigenetic Alterations in Cancer -- 14. Immunodeficiency and Cancer -- Section C. Diagnosing Cancer -- 15. Flow Cytometry in Oncologic Diagnosis -- 16. WHO Classification of Hematologic Malignancies -- 17. Pathology, Biomarkers, and Molecular Diagnostics -- 18. Imaging -- Section D. Preventing and Treating Cancer -- 19. Biostatistics and Bioinformatics in Clinical Trials -- 20. Structures Supporting Cancer Clinical Trials -- 21. Oncology and Health Care Policy -- 22. Discovery and Characterization of Cancer Genetic Susceptibility Alleles -- 23. Cancer Prevention, Screening, and Early Detection -- 24. Nicotine Dependence: Current Treatments and Future Directions -- 25. Surgical Interventions in Cancer -- 26. Establishing and Maintaining Vascular Access -- 27. Basics of Radiation Therapy -- 28. Therapeutic Targeting of Cancer Cells: Era of Molecularly Targeted Agents -- 29. Cancer Pharmacology -- 30. Hematopoietic Stem Cell Transplantation -- 31. Gene Therapy in Oncology -- 32. Therapeutic Antibodies and Immunologic Conjugates -- 33. Complementary and Alternative Medicine -- Part II. Problems Common to Cancer and its Therapy -- Section A. Hematologic Problems and Infections -- 34. Disorders of Blood Cell Production in Clinical Oncology -- 35. Diagnosis, Treatment, and Prevention of Cancer-Associated Venous Thromboembolism -- 36. Infection in the Patient with Cancer -- Section B. Metabolic and Paraneoplastic Syndromes -- 37. Hypercalcemia -- 38. Tumor Lysis Syndrome -- 39. Paraneoplastic Neurologic Syndromes -- 40. Cancer-Related Pain -- 41. Cancer Cachexia -- 42. Nausea and Vomiting -- 43. Oral Complications -- 44. Dermatologic Toxicities of Anticancer Therapy -- 45. Fatigue -- 46. Caring for Patients at the End of Life -- Section C. Local Effects of Cancer and Its Metastasis -- 47. Acute Abdomen, Bowel/Biliary Obstruction, and Fistula -- 48. Superior Vena Cava Syndrome -- 49. Spinal Cord Compression -- 50. Brain Metastases and Neoplastic Meningitis -- 51. Bone Metastases -- 52. Lung Metastases -- 53. Liver Metastases -- 54. Malignant Effusions -- Section D. Complications of Therapy -- 55. Rehabilitation of Individuals with Cancer -- 56. Survivorship -- 57. Neurologic Complications -- 58. Pulmonary Complications of Anticancer Treatment -- 59. Cardiac Effects of Cancer Therapy -- 60. Reproductive Complications -- 61. Endocrine Complications -- 62. Second Malignant Neoplasms -- Section E. Special Populations -- 63. Cancer in the Elderly: Biology, Prevention, and Treatment -- 64. Special Issues in Pregnancy -- 65. Acquired Immunodeficiency Syndrome and Cancer -- Part III. Specific Malignancies -- 66. Cancer of the Central Nervous System -- 67. Eye, Orbit, and Adnexal Structures -- 68. Cancer of the Head and Neck -- 69. Melanoma -- 70. Nonmelanoma Skin Cancers: Basal Cell and Squamous Cell Carcinomas -- 71. Cancer of the Endocrine System -- 72. Cancer of the Lung: Non-Small Cell Lung Cancer and Small Cell Lung Cancer -- 73. Diseases of the Pleura and Mediastinum -- 74. Cancer of the Esophagus -- 75. Cancer of the Stomach and Gastroesophageal Junction -- 76. Cancer of the Small Bowel -- 77. Colorectal Cancer -- 78. Cancer of the Rectum -- 79. Cancer of the Anal Canal -- 80. Liver and Bile Duct Cancer -- 81. Carcinoma of the Pancreas -- 82. Cancer of the Kidney -- 83. Bladder Cancer -- 84. Prostate Cancer -- 85. Cancer of the Penis -- 86. Testicular Cancer -- 87. Cancers of the Cervix, Vulva, and Vagina -- 88. Uterine Cancer -- 89. Cancers Arising in the Ovary -- 90. Gestational Trophoblastic Disease -- 91. Cancer of the Breast -- 92. Sarcomas of Bone -- 93. Sarcomas of Soft Tissue -- 94. Carcinoma of Unknown Primary -- 95. Pediatric Solid Tumors -- 96. Childhood Leukemia -- 97. Childhood Lymphoma -- 98. Acute Leukemias in Adults -- 99. Myelodysplastic Syndromes -- 100. Myeloproliferative Neoplasms -- 101. Chronic Myeloid Leukemia -- 102. Chronic Lymphocytic Leukemia -- 103. Hairy Cell Leukemia -- 104. Multiple Myeloma and Related Disorders -- 105. Hodgkin Lymphoma -- 106. Non-Hodgkin Lymphoma -- 107. Cutaneous T-Cell Lymphoma and Cutaneous B-Cell Lymphoma -- 108. Adult T-Cell Leukemia-Lymphoma.
  • 2008
    Abeloff, Martin D.; Armitage, James O.; Kastan, M. B.; McKenna, W. Gillies; Niederhuber, John E.
    Status: Not Checked OutLane Catalog Record
  • 2009 ClinicalKey
    Abernathy, Charles; Harken, Alden H.; Moore, Ernest Eugene.
    The new edition of this leading volume in the Secrets Series® offers the very latest overview of surgical practice. A two-color page layout, question-and-answer approach, and a list of the "Top 100 Secrets" in surgery gives you the perfect concise board review or handy clinical reference, while updated coverage throughout equips you with all of the most current and essential knowledge in the field. Valuable pearls, tips, and memory aids make this the perfect resource for a fast surgical review or reference. Uses bulleted lists, tables, short answers, and a highly detailed index to expedite reference. Includes pearls, tips, and memory aids, making it perfect as a handy surgical review for board exams or clinical reference. Covers all of today's most common surgical procedures and techniques. Presents a "Controversies" section in many chapters that highlights the pros and cons of selected procedures and approaches. Features a compact trim size for enhanced portability.
  • 2007 Springer
    Barrow, Colin J.; Small, David H.
    A Brief Introduction to the History of the β-Amyloid Protein (Aβ) of Alzheimer's Disease / David Small and Colin Barrow -- The Aβcentric Pathway of Alzheimer's Disease / Victor Villemagne, Roberto Cappai, Kevin Barnham, Robert Cherny, Carlos Opazo, Kathy Novakovic, Christopher Rowe and Colin Masters -- The Function of the Amyloid Precursor Protein Family / Roberto Cappai, B. Elise Needham and Giuseppe Ciccotosto -- The Involvement of Aβ in the Neuroinflammatory Response / Piet Eikelenboom, Willem van Gool, Annemieke Rozemuller, Wiep Scheper, Rob Veerhuis and Jeroen Hoozemans -- Amyloid β-Peptide(1-42), Oxidative Stress, and Alzheimer's Disease / D. Butterfield -- Amyloid Toxicity, Synaptic Dysfunction, and the Biochemistry of Neurodegeneration in Alzheimer's Disease / Judy Ng, Marie-Isabel Aguilar and David Small -- Aβ Variants and Their Impact on Amyloid Formation and Alzheimer's Disease Progression / Laszlo Otvos -- Copper Coordination by β-Amyloid and the Neuropathology of Alzheimer's Disease / Cyril Curtain and Kevin Barnham -- Cholesterol and Alzheimer's Disease / Joanna Cordy and Benjamin Wolozin -- Amyloid β-Peptide and Central Cholinergic Neurons: Involvement in Normal Brain Function and Alzheimer's Disease Pathology / Satyabrata Karn, Z. Wei, David MacTavish, Doreen Kabogo, Mee-Sook Song and Jack Jhamandas -- Physiologic and Neurotoxic Properties of Aβ Peptides / Gillian Gregory, Claire Shepherd and Glenda Halliday -- Impact of β-Amyloid on the Tau Pathology in Tau Transgenic Mouse and Tissue Culture Models / Jürgen Götz, Della David and Lars Ittner -- Glial Cells and Aβ Peptides in Alzheimer's Disease Pathogenesis / Gilbert Siu, Peter Clifford, Mary Kosciuk, Venkat Venkataraman and Robert Nagele -- The Role of Presenilins in Aβ-Induced Cell Death in Alzheimer's Disease / Maria Ankarcrona -- Immunotherapeutic Approaches to Alzheimer's Disease / Josef Karkos -- Mouse Models of Alzheimer's Disease / Dwight German.
  • 2009 Springer
    Lemaire, Antoine.
  • 2009 Springer
  • 2008 Springer
    Bouet, Jean-François; Pire, Jean-Claude.
  • 2009 Springer
    Ritz, Patrick; Dargent, Jérôme.
  • 2010 Springer
    Hébert, Bernard.
  • 2010 Springer
    Turpin, Jean-Claude.
  • 2008 Springer
    Bretelle, Florence; Capelle, Marianne.
  • 2007 Springer
    Agutter, Paul S.; Wheatley, D. N.
    Ingredients of the simplest cells (prokaryotes and the sizes of their contents) -- Bigger cells (eukaryotic cells and their contents) -- Hives of industry (a survey of intermediary metabolism) -- Delights of transport (how the cell's contents are moved around) -- As if standing still (cellular homeostasis and regulatory processes) -- Internal state and gene expression (transcription and its control) -- Sustaining and changing the internal state (the interrelationship between gene expression and the cell's current composition and functional state) -- Responding to the environment (signal processing, gene expression and internal state) -- The living state (a characterization of 'life') -- Stability and change in DNA (how genes can be altered) -- The spice of life (diversity, natural selection and symbiosis) -- Curriculum vitae (an outline history of life on Earth) -- The origin of life (some major ideas and unanswered questions) -- Other worlds (the possibility of extraterrestrial life) -- Intelligent behavior and brains (the biological meaning of "intelligence") -- Human evolution (human intelligence and the question of human uniqueness) -- Cells, brains and computers: towards a characterisation of mind.
  • 2006
    Abrams, Herbert L.; Baum, Stanley; Pentecost, Michael J.
    Status: Not Checked OutLane Catalog Record
    Angiography of lower extremity peripheral vascular disease / Geoffrey A. Gardiner Jr., Steven C. Wagner -- Femoropopliteal revascularization / Eric C. Martin -- Infrapopliteal revascularization / Marcy B. Jagust, Thomas A. Sos -- Evaluation and endovascular therapy for renal artery stenosis / Alan H. Matsumoto ... [et al.] -- Endovascular interventions for acute and chronic mesenteric ischemia / Daniel A. Leung ... [et al.] -- Endovascular stent grafts for treatment of thoracic aortic diseases / David S. Wang, Michael D. Dake -- Endovascular repair of abdominal aortic aneurysms / Richard A. Baum, Roy K. Greenberg -- Percutaneous coronary intervention and related techniques / Sameer Rohatgi, Howard C. Herrmann, John W. Hirshfeld, Jr -- Arteriographic diagnosis and treatment of gastrointestinal bleeding / Stanley Baum -- Interventional therapies for hepatic malignancy / Michael J. Pentecost -- Benign biliary obstruction / Roy L. Gordon -- Malignant obstruction of the hepatobiliary system / Anthony C. Venbrux ... [et al.] -- Liver transplantation: associated interventions / Robert K. Kerlan, Jr., Jeanne M. LaBerge -- Percutaneous management of portal hypertension / Ziv J. Haskal -- Percutaneous gastrostomy and gastrojejunostomy / Daniel B. Brown, Daniel Picus -- Interventional radiology of the lacrimal system / Ho-Young Song, Deok Hee Lee, Sung-Gwon Kang -- Esophageal stent placement / Ho-Young Song, Hyun Ki Yoon, Kyu-Bo Sung -- Colonic stenting / Manuel Maynar ... [et al.] -- Percutaneous management of biliary calculi / Aalpen A. Patel, S. William Stavropoulos, Constantin Cope -- Percutaneous cholecystostomy / S. William Stavropoulos, Aalpen A. Patel, Constantin Cope -- Nephroureteral obstruction / Parvati Ramchandani -- Renal calculus disease / Parvati Ramchandani -- Lower genitourinary tract / Flavio Castaûeda -- Interventions in urinary diversions / Parvati Ramchandani -- Renal cysts and urinomas / Michael Darcy -- Perspectives of varicocele management / Richard Shlansky-Goldberg, Jeffery Arthur Solomon -- Uterine fibroid embolization / James B. Spies -- Obstetrical hemorrhage / Filip Banovac -- Pelvic venous incompetence: pelvic congestion syndrome / Anthony C. Venbrux -- Revascularization in the central nervous system / Robert W. Hurst -- Endovascular therapy of cerebral arteriovenous malformations / Tony P. Smith -- Intracranial aneurysm therapy / Michael J. Alexander -- Neuroendovascular therapy of intracranial, extra-axial lesions / Jason Allen, Tibor Bescke, Peter Kim Nelson -- Transcatheter bronchial artery embolization for inflammation (hemoptysis) / Matthew A. Mauro, Charles T. Burke, Paul F. Jaques -- Thoracic abscesses and malignant pleural effusions / Debra A. Gervais, Giles W. Boland, Steven L. Dawson -- Pulmonary arteriovenous malformations / Jeffrey S. Pollak, Robert I. White, Jr -- Management of chylothorax / Constantin Cope -- Preintervention assessment, intraprocedure management, postintervention care / Klemens H. Barth -- The emergency treatment of reaction to contrast material / Rebecca A. Barnett -- Interventional pain procedures for cancer pain / Phillip Phan, Allen W. Burton -- Intradiskal electrothermal therapy (IDET) and its role in spinal pain management / Jeffrey A. Saal -- Vascular ultrasound / Edward G. Grant -- Multidetector-row computed tomographic angiography technique and clinical applications / Jeffrey C. Hellinger, Geoffrey D. Rubin -- Magnetic resonance angiography / Frank J. Thornton, Thomas M. Grist -- Basic surgical techniques for the interventional radiologist / Jeffrey P. Carpenter, Edward Y. Woo -- Catheters, methods, and injectors for superselective catheterization / S. William Stavropoulos, Dheeraj Rajan, Constantin Cope -- Agents for small vessel/tissue embolization and transcatheter tissue ablation: current status and the future / Aalpen A. Patel, Michael C. Soulen -- Mechanical embolic agents / Herb Lustberg, Jeffrey S. Pollak -- Balloon angioplasty catheters / Gary J. Becker -- Vascular stents / Elliot Levy -- Principles of selective thrombolysis / Anne Roberts -- Thrombolysis: clinical applications / Anne Roberts -- Percutaneous image-guided biopsy / Jeffrey S. Moulton ... [et al.] -- Percutaneous aortoiliac intervention in vascular disease / Janice M. Newsome, Kenneth S. Rholl -- Tracheobronchial balloon dilatation and stent placement / Ji Hoon Shin, Gi-Young Ko, Ho-Young Song -- Interventional therapy of pulmonary embolism / Renan Uflacker -- Arteriography and transcatheter treatment of extremity trauma / Michael D. Katz, Sue E. Hanks -- Angiographic management of hemorrhage in pelvic fractures / John A. Kaufman, Arthur C. Waltman -- Transcatheter arterial embolization in the management of splenic trauma / Brian Stainken -- Arteriography and endovascular management of renal trauma / Sue E. Hanks, Michael D. Katz -- Embolotherapy of hepatic trauma / Michael D. Katz, Sue E. Hanks -- Pediatric interventional angiography / Josee Dubois, Laurent Garel, J.A. Gordon Culham -- Percutaneous treatment of abdominal abscesses / Debra A. Gervais, Steven L. Dawson -- Percutaneous drainage of pelvic abscesses and fluid collections / Debra A. Gervais, Steven L. Dawson -- Interventional radiology of venous insufficiency / Robert J. Min -- Percutaneous vertebroplasty / Mary E. Jensen, Avery J. Evans -- Venous thrombolysis and stenting / Paul C. Lakin, Sean M. Carr -- Venous access / Matthew A. Mauro, Susan M. Weeks -- Vena cava filters / Gregory M. Soares, Timothy P. Murphy -- Percutaneous vascular and nonvascular foreign body retrieval / Christoph A. Binkert, Frederick S. Keller, Josef Rösch -- Hemangiomas and vascular malformations / Robert J. Rosen, Francine Blei -- Recanalization of dialysis fistulas / Anne Roberts.
  • 2015 Springer
    Gloster, Hugh M.
  • 2016 Springer
    Conrad, Kevin.
    This concise guide covers the evolution and expanding scope of hospital medicine and the variety of clinical, ethical and administrative situations a Hospitalist encounters. 500 questions on inpatient care, co-management of patients and hospital system management are provided with the goal of assessing clinical and academic competency. Questions feature actual cases with evidence-based solutions. Useful to physicians, house staff and advanced nurse practitioners, this up-to-date referenced learning text encompasses all aspects of hospital care.
  • 2012 Wiley
    Avdeef, Alex.
    Introduction Transport model pKa determination -- Octanol-water partitioning -- Liposome-water partitioning -- Solubility -- Permeability -- Pampa -- Permeability Caco 2/MDCK -- Permeability blood brain barrier.
  • v. 1, 3-6, Supp. 1, 1967.
    Status: Not Checked OutLane Catalog Record
    1. [Symposia I-III] -- 2. [Symposia IV-VII] -- 3. Colloquia I-XIV -- 4. General sessions A-F -- 5. General sessions G-J -- [6] Author index -- [7] Supplement I-
  • 2008 Cold Spring Harb Lab Press
    Grodzicker, Terri; Stewart, David J.; Stillman, Bruce.
  • 1972-
  • v. 1-5, 1953-60.
    Berens, Conrad; Sheppard, Louis Benjamin.
    Status: Not Checked OutLane Catalog Record
  • 2016 Springer
    Krishnaswami, Sanjay; Swaroop, Mamta.
    Part 1. General Considerations -- 1. Global Burden of Surgical Disease and the Role of Academia -- 2. Promoting, Developing, and Sustaining Academic Global Surgery Programs.-3. Ethics in Global Surgery -- Part 2. Career -- 4. Preparing and Sustaining Your Career in Academic Global Surgery -- 5. Balancing Global Surgery with Traditional Career and Life Demands -- Part 3. Clinical -- 6. Guidelines and Parameters for Ideal Short-Term Interactions: Disaster Relief -- 7. How to Set Up for an Ideal Long Term Clinical Interaction -- Part 4. Research -- 8. Current Research Needs and Priorities -- 9. Research Methods Appropriate and Applicable to Global Surgery -- 10. Funding for Global Surgical Programs -- Part 5. Education -- 11. Developing Educational Opportunities for Trainees on Both Sides -- 12. The Role of Educational Research in the Global Setting -- Part 6. Resources -- 13. Tools Useful for the Academic Global Surgeon.
  • 2008 ebrary
    Vick, Julia Miller; Furlong, Jennifer S.
    What you should know before you start -- The structure of academic careers -- Hiring from the institution's point of view -- Planning and timing your search -- Becoming a job candidate: the timetable for your search -- Deciding where and when to apply -- The importance of advisors and professional networks -- Conference presentations and networking -- Letters of recommendation -- Learning about openings -- Written materials for the search: suggestions and samples -- Responding to position announcements -- Vitas -- Additional application materials -- Web sites -- Job hunting correspondence -- Conducting the search -- Interviewing -- Off-site interviews: conference/convention and telephone interviews -- Campus interviews -- Job offers, negotiations, acceptances, and rejections -- After you take the job -- Starting the job -- Knowing about and getting tenure -- Changing jobs -- Additional considerations -- Dual career couples, pregnant on the job market, and related concerns -- International scholars, older candidates, gaps in your vita -- Thinking about the expanded job market.
  • 2006 Springer
    Taylor, Robert B.
    Deciding on an academic career. -- About an academic career. -- What you need to know about the academic medical center. -- Finding the academic job you want. -- Basic academic skills: clinical practice, teaching, and scholarship. -- Advanced academic skills: doing research, getting grants, and writing for publication. -- Administrative skills. -- Academic medicine success skills. -- How to manage your career and your life. -- Planning for the future. -- Appendix 1: Glossary. -- Appendix 2: Collected academic medical aphorisms. -- Appendix 3: Allopathic medical schools in the United States. -- Appendix 4: Osteopathic medical schools in the United States. -- Appendix 5: Medical schools in Canada.
  • 2013 Springer
    Pizzo, Philip A.; Roberts, Laura Weiss.
    Attaining professional success and finding personal happiness in academic medicine is not an easy path, yet both are critical if the future is to be brighter through better science, better clinical care, better training, better responsiveness to communities, and better stewardship and leadership in the health professions. This concise, easy to read title consists of "mini" chapters intended as a resource to assist early- and middle-career physicians, clinicians, and scientists in understanding the unique mission of academic medicine and building creative, effective, and inspiring careers in a challenging field.
  • 2006. Springer
    Arthur, Douglas W.; Vicini, Frank A.; Wazer, David E.
    Also available: Print – 2006
  • 2009 Springer
    Arthur, Douglas W.; Vicini, Frank A.; Wazer, David E.
  • 2014 ScienceDirect
    Suh, Jung W.; Kim, Youngmin.
    "Beyond simulation and algorithm development, many developers increasingly use MATLAB even for product deployment in computationally heavy fields. This often demands that MATLAB codes run faster by leveraging the distributed parallelism of Graphics Processing Units (GPUs). While MATLAB successfully provides high-level functions as a simulation tool for rapid prototyping, the underlying details and knowledge needed for utilizing GPUs make MATLAB users hesitate to step into it. Accelerating MATLAB with GPUs offers a primer on bridging this gap. Starting with the basics, setting up MATLAB for CUDA (in Windows, Linux and Mac OS X) and profiling, it then guides users through advanced topics such as CUDA libraries. The authors share their experience developing algorithms using MATLAB, C++ and GPUs for huge datasets, modifying MATLAB codes to better utilize the computational power of GPUs, and integrating them into commercial software products. Throughout the book, they demonstrate many example codes that can be used as templates of C-MEX and CUDA codes for readers' projects. Download example codes from the publisher's website: http://booksite.elsevier.com/9780124080805/ Shows how to accelerate MATLAB codes through the GPU for parallel processing, with minimal hardware knowledge -- Explains the related background on hardware, architecture and programming for ease of use -- Provides simple worked examples of MATLAB and CUDA C codes as well as templates that can be reused in real-world projects."--Provided by publisher.
  • 2012 Springer
    Simonsen, Sigmund.
    This book is the first major work that addresses a core question in biomedical research: the question of acceptable risk. The acceptable level of risks is regulated by the requirement of proportionality in biomedical research law, which state that the risk and burden to the participant must be in proportion to potential benefits to the participant, society or science. This investigation addresses research on healthy volunteers, children, vulnerable subjects, and includes placebo controlled clinical trials.
  • 2013 Wiley
    Johns, Louise C.; Morris, Eric M. J.; Oliver, Joseph E.
    Introduction to mindfulness and acceptance-based therapies for psychosis / Joseph E. Oliver, Candice Joseph, Majella Byrne, Louise C. Johns and Eric M.J. Morris -- Theory on voices / Fran Shawyer, Neil Thomas, Eric M.J. Morris and John Farhall -- Emotional processing and metacognitive awareness / Claire Hepworth, Helen Startup and Daniel Freeman -- Clinical assessment and assessment measures / John Farhall, Fran Shawyer, Neil Thomas and Eric M.J. Morris -- Acceptance and commitment therapy case formulation / Patty Bach -- Engaging people with psychosis in acceptance and commitment therapy and mindfulness / Brandon A. Gaudiano and Andrew M. Busch -- Acceptance and commitment therapy for voices / Neil Thomas, Eric M.J. Morris, Fran Shawyer and John Farhall -- Acceptance and commitment therapy for delusions / José Manuel García Montes, Marino Pérez Álvarez and Salvador Perona Garcelán -- Acceptance and commitment therapy for emotional dysfunction following psychosis / Ross White -- Person-based cognitive therapy for distressing psychosis / Lyn Ellett -- Spirituality: a new way into understanding psychosis / Isabel Clarke -- The service user experience of acceptance and commitment therapy and person-based cognitive therapy / Joseph E. Oliver, Mark Hayward, Helena B. McGuiness -- Acceptance and commitment therapy for first-episode psychosis / Joseph E. Oliver and Eric M.J. Morris -- Acceptance and commitment therapy for psychosis in acute psychiatric admission settings / Gordon Mitchell and Amy McArthur -- Developing acceptance and commitment therapy for psychosis as a group-based intervention / Amy McArthur, Gordon Mitchell and Louise C. Johns -- Group person-based cognitive therapy for distressing psychosis / Clara Strauss and Mark Hayward -- Appendix A: chessboard metaphor -- Appendix B: leaves-on-the-stream metaphor -- Appendix C: passengers-on-the-bus metaphor -- Appendix D: person-in-the-hole metaphor -- Appendix E: polygraph metaphor -- Appendix F: see the wood for the trees (and other helpful advice for living life) -- Appendix G: skiing metaphor -- Appendix H: tug-of-war-with-the-monster metaphor.
  • 2007 ProQuest Safari
    MacDonald, Matthew.
  • Click LINK above for additional Print location/circulation status.
    2007 ProQuest Safari
    Bluttman, Ken; Freeze, Wayne S.
    Also available: Print – 2007
  • 2006
    Willinsky, John.
    Status: Not Checked OutLane Catalog Record
    Opening -- Access -- Copyright -- Associations -- Economics -- Cooperative -- Development -- Public -- Politics - Rights -- Reading -- indexing -- History -- Appendixes. A. Ten flavors of open access -- B. Scholarly association budgets -- C. Journal management economics -- D. An Open access cooperative.
  • 2014 WHO
    Also available: Print – 2014
  • McGraw-Hill, Users must register and log in to access some features. To maintain their personal accounts users must log in to AEM via the Stanford network every 90 days
    AccessEmergency Medicine is a complete online service that allows users to quickly search the diagnosis and treatment of a broad range of emergency cases with videos.
  • AccessEmergency Medicine, Users must register and sign in to take a test. To maintain their personal accounts users must log in to AEM via the Stanford network every 90 days
    Interactive self-assessment section of AccessEmergency Medicine website. Allows users to create and take custom tests based on standard review texts.
  • AccessMedicine
    Toy, Eugene C.
    Clinical cases selected from the LANGE Case Files series, edited by Eugene C. Toy, MD.
  • McGraw-Hill, Users must create a personal profile in AccessMedicine using a non-mobile browser, and log into AccessMedicine with that username and password on the mobile device (optimized for): iPhone, Android, and BlackBerry Bold.
    The AccessMedicine mobile website includes Harrison's Online, CURRENT Medical Diagnosis and Treatment, Picture Galleries from Fitzpatrick's Color Atlas and Synopsis of Clinical Dermatology, Clinician's Pocket Reference: The Scut Monkey, CURRENT Practice Guidelines in Primary Care, Diagnostic Tests from Pocket Guide to Diagnostic Tests, Quick Answers, Diagnosaurus, and Drug monographs.
  • McGraw-Hill
    A repository of medical knowledge from internal medicine, cardiology, genetics, pharmacy, diagnosis and management, basic sciences, patient care, and more. Continuously expanding, all databases in the repository contain the latest editions of selected medical titles.
  • 2014 AccessSurgery, Users must register and sign in to take a test
    Interactive self-assessment section of AccessSurgery website. Allows users to create and take custom tests based on standard review texts.
  • 2015 ClinicalKey
    Raby, Nigel; Berman, Laurence; De Lacey, Gerald; Morley, Simon.
    Since it was first published, Accident and Emergency Radiology: A Survival Guide has become the classic in-my-pocket-reference and an indispensable aid to all those who work in the Emergency Department. The core and substantial value lies in the step-by-step analytical approaches which help you to answer this question: "These images look normal to me, but . . . how can I be sure that I am not missing a subtle but important abnormality?" Ensure accuracy in reading and interpretation of any given image. Common sources of error and diagnostic difficulty are highlighted. Prevent mistakes. Pitfalls and associated abnormalities are emphasized throughout. Avoid misdiagnoses. Normal anatomy is outlined alongside schemes for detecting variants of the norm. Each chapter concludes with a summary of key points. Will provide a useful overview of the most important features in diagnosis and interpretation.Easily grasp difficult anatomical concepts. Radiographs accompanied by clear, explanatory line-drawings.
  • Benny Ho.
    Status: Not Checked OutLane Catalog Record
  • 2015 Springer
    Melvin, John; Nahum, Alan M.; Yoganandan, Narayan.
    This book provides a state-of-the-art look at the applied biomechanics of accidental injury and prevention. The editors, Drs. Narayan Yoganandan, Alan M. Nahum and John W. Melvin are recognized international leaders and researchers in injury biomechanics, prevention and trauma medicine. They have assembled renowned researchers as authors for 29 chapters to cover individual aspects of human injury assessment and prevention. This third edition is thoroughly revised and expanded with new chapters in different fields. Topics covered address automotive, aviation, military and other environments. Field data collection; injury coding/scaling; injury epidemiology; mechanisms of injury; human tolerance to injury; simulations using experimental, complex computational models (finite element modeling) and statistical processes; anthropomorphic test device design, development and validation for crashworthiness applications in topics cited above; and current regulations are covered. Risk functions and injury criteria for various body regions are included. Adult and pediatric populations are addressed. The exhaustive list of references in many areas along with the latest developments is valuable to all those involved or intend to pursue this important topic on human injury biomechanics and prevention. The expanded edition will interest a variety of scholars and professionals including physicians, biomedical researchers in many disciplines, basic scientists, attorneys and jurists involved in accidental injury cases, and governmental bodies. It is hoped that this book will foster multidisciplinary collaborations by medical and engineering researchers, and academicians and practicing physicians for injury assessment and prevention and stimulate more applied research, education and training in the field of accidental-injury causation and prevention.
  • 2007
    Linden, David J.
    "A guide to the strange and often illogical world of neural function, 'The accidental mind' shows how the brain is not an optimized, general-purpose problem-solving machine, but rather a weird agglomeration of ad-hoc solutions that have been piled on through millions of years of evolutionary history. Moreover Linden tells us how the constraints of evolved brain design have ultimately led to almost every transcendent human foible : our long childhoods, our extensive memory capacity, our search for love and long-term relationships, our need to create compelling narrative, and ultimately, the universal cultural impulse to create both religious and scientific explanations. With forays into evolutionary biology, this analysis of mental function answers some of our most common questions about how we've come to be who we are." --book jacket.
  • 2013
    Rodriguez, Jesse M.; Altman, Russ B.; Batzoglou, Serafim; Bustamante, Carlos.
    The predisposition to many diseases is strongly influenced by the genome of an individual. However, the association between the genome and most diseases is not fully understood, so there is an ongoing effort to characterize these associations. One way to characterize disease-genome associations is by studying the familial and ancestral origin of individuals in the context of disease. This kind of study relies on the fact that individuals with shared origins tend to have genomes and phenotypes that are similar to one another. Detailed information regarding familial and ancestral origin is often unknown, however, it can be inferred computationally by examining the genome. Therefore, it is important that we have accurate methods to infer this information in order to facilitate disease-genome associations. In this dissertation, I describe the contributions I have made to accurately inferring the ancestry and relatedness of individuals based on their genomes. First, I describe my work on ALLOY, a method to infer the ancestral origin of segments of the genome based on a factorial HMM. Next, I present PARENTE, a method to infer which individuals in a group are related to one another by detecting genomic segments that are identical-by-descent (IBD) using an embedded likelihood ratio test. Finally, I present PARENTE2, an extension of PARENTE that incorporates linkage disequilibrium information and results in significantly higher accuracy.
  • v. 4, 2009.
    Otis-Green, Shirley.
    Status: Not Checked OutLane Catalog Record
    "The primary aim of this innovative psycho-oncology educational initiative is to improve the delivery of palliative care by psychologists, social workers and spiritual care professionals through an intensive advocacy and leadership training program"--Website.
  • 2015 Springer
    Filardi, Pasquale Perrone.
    This book summarizes how the renin angiotensin system is implicated in the progression of atherosclerotic disease as well as of left ventricular dysfunction and reviews the action of angiotensin converting enzyme inhibitors and AT1 receptor antagonists on reducing morbidity and mortality in patients with left ventricular dysfunction or in those at high cardiovascular risk with preserved ventricular function. ACEi and ARBS in Hypertension and Heart Failure is a highly practical reference reviewing the evidence and providing a rationale for the appropriate use of RAS antagonists in cardiovascular diseases. It is written in an easy-to-follow format and with many illustrations to aid clarity and the assimilation of information. Each chapter is written by established authorities in their fields who are also experienced in explaining often complex concepts. The result is a unique book which is not only comprehensive but also clear and useful for the busy medical practitioner.
  • 2016 Springer
    Fisichella, P. Marco; Herbella, Fernando A. M.; Patti, Marco G.
  • 2011 ebrary
    Over, A. Mead.
    The global AIDS transition: a feasible objective for AIDS policy -- Using incentives to prevent HIV infections -- Sustaining and leveraging AIDS treatment -- Appendix A. Alternative approaches to estimating the average cost of antiretroviral treatment -- Appendix B. A meta-analysis of the health benefits of early initiation of antiretroviral therapy -- Appendix C. A model for projecting future AIDS treatment costs.
  • 2006 Springer
    Gunderman, Richard B.
    Education matters -- Theoretical insights -- Understanding learners -- Promoting learners -- Educational excellence -- Educational technique -- Obstacles to excellence -- Organizational excellence -- Center of excellence -- Educational leadership.
    Also available: Print – 2006
  • 2014 Wiley
    Abraham, Sasha; Leng, Gillian; Moore, Val.
    Practical actions for healthcare providers / Val Moore -- Identifying a high quality evidence base / Paul Chrisp and Sara Twaddle -- Key challenges to implementation and effective interventions / Elaine Whitby and Julie Royce -- Using financial systems to support improved care / Jennifer Field -- Using measurement to support change and improvements in healthcare / Nick Baillie -- Conclusion and reflections / Danny Keenan and Sasha Abraham.
  • 2014 CRCnetBASE
    Dishongh, Rhonda; Dibeehi, Qaalfa; Erickson, Gregory D.; Janevska, Kalina.
    1. Begin to spark -- 2. Personalize to motivate -- 3. Serve to lead -- 4. Connect to engage -- 5. Fail then account -- 6. Succeed then recognize -- 7. Inject fun to release pressure -- 8. Measure to coach -- 9. Action program spirit to achieve excellence -- 10. Get help to be independent.
  • v. 1-3, 1970-1975.
    Burmeister, Karl Heinz.
    Status: Not Checked OutLane Catalog Record
    v. 1. Biographie -- v. 2. Bibliographie -- v. 3. Briefwechsel
  • 2007 Springer
    Almekinders, Louis; Maffulli, Nicola.
    Also available: Print – 2007
  • 2009 Springer
    Nunley, James A.
  • v. 1-2, 1995-2001.
    Abad-Casintahan, Maria Flordeliz A.; Ackerman, A. Bernard; Cavegn, Brigitta M.; Mones, Joan M.; Robinson, Mary Jo.
    Status: Not Checked OutLane Catalog Record
  • 2013 Springer
    Fleming, Braden C.; Murray, Martha M.; Vavken, Patrick.
  • 2012 Springer
    Barber-Westin, Sue D.; Noyes, Frank R.
    Nearly a million anterior cruciate ligament (ACL) injuries occur each year worldwide, causing long-term problems in the knee joint. This textbook examines the short- and long-term impacts of ACL injuries on the basis of hundreds of published studies. Risk factors for such injuries are explored using data from hypothesis-driven investigations, and possible causes of the higher risk of noncontact ACL injuries in female athletes are analyzed. Neuromuscular training programs shown to reduce the rate of these injuries in female athletes are described in step-by-step detail with the aid of numerous color photographs and video demonstrations. In addition, detailed descriptions are provided for rehabilitation programs to be used after ACL reconstruction in order to reduce the risk of a future injury.
  • 2013 Springer
    Monllau, Joan Carles; Sanchis-Alfonso, Vicente.
    "The ACL-Deficient Knee: A Problem Solving Approach, focuses on problem analysis and problem solving, as well as analyzing the possibility of prevention. In each chapter, the biomechanics, anatomy, etc. that are relevant to the topic are reviewed. There are chapters where highly specialized surgical techniques are presented (v. gr. double bundle reconstruction or meniscal transplant), as well as developing areas such as ACL tears in children, where we are finding a growing number of injuries due to the increase of sports at early ages."--publisher's website
  • 2007
    Aehlert, Barbara.
    Status: Not Checked OutLane Catalog Record
  • NGC
  • 2014 Springer
    Zeichner, Joshua A.
    Dermatologists commonly treat acne, which affects 40 to 50 million Americans each year and about 85 percent of all patients at some point in their lives. Dermatologists, primary care doctors, and pediatricians see these patients every day in practice. It is important to treat the skin effectively not only to reduce the risk of physical scarring, but also to address the negative psychosocial impact this disease carries. Improving the skin can improve self-confidence, interpersonal relationships, and performance in school or at work. Acneiform Eruptions in Dermatology is a practical, full-color guide to the differential diagnosis of acne vulgaris and the treatment of acne-like conditions. It is organized into sections by subtype of condition (e.g., infections, genetic syndromes, medication-caused) and includes a section of variants of acne that may be misdiagnosed. Within the sections, individual chapters discuss each variant of the condition and begin with a helpful bulleted summary of its defining clinical features. Extensive color clinical images appear throughout the book.
  • 2007 Springer
    André, Michael P.
  • STAT!Ref, Access ending March 1, 2016.
    This point-of-care decision support tool provides access to hundreds of evidence-based recommendations on diagnosis, therapy, prevention, screening and more. Includes AHFS DI Essentials.
  • 2007 Springer
    Benson, Deborah M.; Elbaum, Jean.
  • 2007 Springer
    Ishikawa, Isao.
  • 2015 Springer
    Beigi, Pooya Khan Mohammad; Maverakis, Emanual.
    1. History of Acrodermatitis Enteropathica -- 2. Epidemiology and Etiology -- 2.1. Epidemiology -- 2.2. Etiology -- 2.2.1. Molecular Etiology of AE -- 2.2.2. Hypothetical Etiology 1: the Alteration of Zinc Bioavailability -- 2.2.3. Hypothetical Etiology 2: a Defective Zinc Transporter -- 2.2.4. Alternative Forms of AE-like Zinc Deficiencies -- 3. Analysis of Disorder -- 3.1. Clinical Forms of AE -- 3.2. Nomenclature of Zinc Deficiencies -- 3.3. Acquired Non-hereditary Zinc Deficiency -- 3.3.1. Zinc Deficient Maternal Breast Milk -- 3.3.2. Zinc Deficient Caused by Metabolism Disorders -- 4. Clinical Symptoms -- 5. Diagnosis -- 5.1. Laboratory Diagnosis of Zinc Deficiency -- 5.2. Histopathology -- 5.3. Biological Diagnosis of AE -- 5.4. Clinical Diagnosis -- 5.5. Molecular Diagnosis -- 5.6. Differential Diagnosis -- 6. Disease Course and Treatment -- 6.1. Treatment -- 7. The Role of Zinc in Different Body Systems -- 7.1. Biochemistry of Zinc Metabolism -- 7.2. Skin and Hair Physiology -- 7.3. Gastrointestinal System and Other Organs -- 7.4. Neurological Development, Growth, and Mental Status -- 7.5. Enzymes -- 7.6. Endocrine System -- 7.7. Metabolism of Nucleic Acids -- 7.8. Mitosis and Meiosis Cycles -- 7.9. Cell Membranes -- 7.10. Synthesis of Proteins and Collagen -- 7.11. Immune System -- 8. History of AE in Adults -- 9. Iranian Hospital Cases in Literature -- 9.1. Patient One -- 9.2. Patient Two -- 9.3. Patient Three -- 9.4. Patient Four -- 9.5. Zinc Deficiency Similarities to AE in Infants (Fifth Patient) -- 10. Clinical Research -- 10.1. Abstract -- 10.2. Synopsis of Study -- 10.3. Purpose of Study -- 10.4. The Considered Hypotheses -- 10.5. Introduction -- 10.5. Methods -- 10.6. Ethical Considerations -- 10.7. Results -- 10.8. Discussion -- 11. Evaluation of Symptoms in Razi Dermatology Hospital -- 12. Case Photos.
  • Mt Data Syst
    Dictionary of acronyms, abbreviations, and initialisms.
  • 2015
    Skopec, Laura.
    In 2014, the American Cancer Society Cancer Action Network (ACS CAN) analyzed coverage of cancer drugs in the health insurance marketplaces created by the Affordable Care Act (ACA) and found that transparency of coverage and cost-sharing requirements were insufficient to allow cancer patients to choose the best plan for their needs. In this updated analysis, we found that coverage transparency has improved somewhat since 2014, but significant barriers remain for cancer patients. To address these barriers, we provide nine recommendations to states and the U.S. Department of Health and Human Services to increase transparency of coverage and cost-sharing, ensure adequate access to medically necessary drugs via an exceptions process, make cost-sharing more predictable and affordable for patients, and monitor the marketplace for evidence of discrimination against persons with high-cost conditions such as cancer.
  • 2015
    Emerging public health information suggests that to reach the U.S. Centers for Disease Control and Prevention's goal to improve health and fitness, prevent disease and disability, and enhance quality of life for all Americans through physical activity, we must create a culture that integrates physical activity into our daily lives. The ACSM American Fitness Index[tm] (AFI) program developed a valid and reliable measure of health and community fitness at a metropolitan level to: Provide community leaders with information to understand the personal, community, societal and environmental influences on physical activity and healthy eating; Develop strategies to promote physical activity at multiple levels of influence; and Take action through local community mobilization with the AFI Community Action Guide, health promotion partners and other best practices
  • 2013
    Emerging public health information suggests that to reach the U.S. Centers for Disease Control and Prevention's goal to improve health and fitness, prevent disease and disability, and enhance quality of life for all Americans through physical activity, we must create a culture that integrates physical activity into our daily lives. The ACSM American Fitness Index[tm] (AFI) program developed a valid and reliable measure of health and community fitness at a metropolitan level to: Provide community leaders with information to understand the personal, community, societal and environmental influences on physical activity and healthy eating; Develop strategies to promote physical activity at multiple levels of influence; and Take action through local community mobilization with the AFI Community Action Guide, health promotion partners and other best practices
  • 2006
    Armstrong, Lawrence E.; Brubaker, Peter H.; Otto, Robert Michael; Whaley, Mitchell H.
    Status: Not Checked OutLane Catalog Record
  • 2007 Ovid
    McKeag, Douglas; Moeller, James L.
    1. Primary care perspective / Douglas B. McKeag and James L. Moeller -- 2. Epidemiology of athletic injuries / Eric D. Zemper and Randall W. Dick -- 3. Exercise physiology and exercise testing / Carl Foster, Matthew J. Faber and John P. Porcari -- 4. Nutrition / Leslie Bonci -- 5. Preparticipation screening / James L. Moeller and Douglas B. McKeag -- 6. Conditioning and training programs for athletes/nonathletes / Sally E. Nogle and Jeffrey S. Monroe -- 7. Exercise as medicine : the role of exercise in treating chronic disease / Eric J. Anish and Chris A. Klenck -- 8. Injury prevention / Michael P. Montico, Joanne Nguyen, Scott W. Eathorne and Martha A. Steele -- 9. Covering athletic competition / Thomas R. Terrell and James L. Moeller -- 10. Management of on-site emergencies / Brent S. E. Rich, Benjamin B. Betteridge and Spencer E. Richards -- 11. Respiratory system / Jeffrey R. Kovan and James L. Moeller -- 12. Gastrointestinal system / Scott A. Paluska -- 13. Cardiovascular system / Vivien Lim, Aravind Rao Kokkirala and Paul D. Thompson -- 14. Head injuries / Margot Putukian -- 15. Peripheral neuropathy / Philip D. Zaneteas -- 16. Genitourinary system / Kevin B. Gebke -- 17. Dermatologic conditions in athletes / Delmas J. Bolin -- 18. Acute infections / Christopher A. McGrew -- 19. Hematology / Thomas H. Trojian and Diana L. Heiman -- 20. Endocrine / Thomas H. Trojian -- 21. Environment / Thomas H. Trojian -- 22. Challenged athletes / Katherine L. Dec -- 23. Common sports-related injuries and illnesses : generic conditions / Douglas B. McKeag -- 24. Head and neck / Scott H. Grindel -- 25. Shoulder and upper extremity / David J. Petron and Umar Khan -- 26. Elbow / Roger L. McCoy II and C. Edward Clark III -- 27. Wrist, hand, and finger injuries / Wade A. Lillegard -- 28. Chest and abdominal wall / Sami F. Rifat -- 29. Thoracic and lumbar spine / Scott W. Eathorne -- 30. Pelvis, hip, and upper leg / David M. Peck -- 31. Knee injuries / E. James Swenson, Jr. -- 32. Lower leg and ankle / Neeru Jayanthi -- 33. Foot and toes / Katherine L. Dec -- 34. Imaging in sports medicine / Jonathan A. Staser and Kenneth A. Buckwalter -- 35. Rehabilitation / Michael D. Jackson -- 36. Sport psychology / Christopher M. Carr -- 37. Drug use / Richard T. Ferro -- 38. Building a sports medicine practice and network / Christopher Madden -- 39. Patient and community education on physical fitness / Eric D. Zemper.
  • 2010 Springer
    Carlier, Marie-France.
    Part 1. Cellular Aspects -- Elementary Cellular Processes Driven by Actin Assembly: Lamellipodia and Filopodia / J. Victor Small and Klemens Rottner -- Coupling Membrane Dynamics to Actin Polymerization / Shiro Suetsugu and Tadaomi Takenawa -- Endocytic Control of Actin-based Motility / Andrea Disanza, Emanuela Frittoli, Chiara Giuliani, Francesca Milanesi and Andrea Palamidessi, et al. -- Actin in Clathrin-Mediated Endocytosis / Marko Kaksonen -- Actin Cytoskeleton and the Dynamics of Immunological Synapse / Viveka Mayya and Michael L. Dustin -- Actin-based Motile Processes in Tumor Cell Invasion / Matthew Oser, Robert Eddy and John Condeelis -- Actin-based Chromosome Movements in Cell Division / Rong Li -- Roles for Actin Dynamics in Cell Movements During Development / Minna Roh-Johnson, Jessica Sullivan-Brown and Bob Goldstein -- Part 2. Molecular Aspects -- Regulation of the Cytoplasmic Actin Monomer Pool in Actin-based Motility / Pekka Lappalainen, Maarit Makkonen and Hongxia Zhao -- From Molecules to Movement: In Vitro Reconstitution of Self-Organized Actin-based Motile Processes / Marie-France Carlier and Dominique Pantaloni -- The WASP-Homology 2 Domain and Cytoskeleton Assembly / Roberto Dominguez -- Formin-Mediated Actin Assembly / David R. Kovar, Andrew J. Bestul, Yujie Li and Bonnie J. Scott -- Visualization of Individual Actin Filament Assembly / Emmanuèle Helfer -- Movement of Cargo in Bacterial Cytoplasm: Bacterial Actin Dynamics Drives Plasmid Segregation / Dyche Mullins -- Part 3. Physical Aspects -- Protrusive Forces Generated by Dendritic Actin Networks During Cell Crawling / Ovijit Chaudhuri and Daniel A. Fletcher -- Mathematical and Physical Modeling of Actin Dynamics in Motile Cells / Anders E. Carlsson and Alex Mogilner -- Force Production by Actin Assembly: Simplified Experimental Systems for a Thorough Modeling / C. Sykes, J. Prost and J.F. Joanny.
  • 2008 Springer
    Chhabra, Deepak; Dos Remedios, Cristobal G.
  • 2015 Karger
    Jemec, G. B. E.; Prow, Tarl W.; Soyer, H. Peter.
    Epidemiology of actinic keratosis / Green, A.C -- Patients' perspectives on actinic keratosis / Esmann, S. -- Photodamage : all signs lead to actinic keratosis and early squamous cell cancer / Wei, J.; Kok, L.F.; Byrne, S.N.; Halliday, G.M. -- Dysregulation of epidermal growth factor receptor in actinic keratosis and squamous cell carcinoma / Joseph, S.R.; Munoz, L.; Gaffney, D.C.; Saunders, N.A.; Simpson, F. -- The actinic keratosis virome : can we prevent squamous cell carcinoma with a vaccine? / Frazer, I.H. -- Do actinic keratoses and superficial squamous cell carcinomas have a specific immunoprofile? / Wells, J.W. -- Mouse models for actinic keratosis and squamous cell carcinoma / Handoko, H.Y.; Ferguson, B.; Walker, G.J. -- Keratinocyte cancer and its precursors in organ transplant patients / Jenni, D.; Hofbauer, G.F.L. -- Clinical features of actinic keratoses and early squamous cell carcinoma / Wheller, L.; Soyer, P. -- The many clinico-pathologic faces of actinic keratosis : an atlas / Massone, C.; Cerroni, L. -- Dermoscopy of actinic keratosis, intraepidermal carcinoma and squamous cell carcinoma / Zalaudek, I.; Argenziano, G. -- The future of keratinocyte skin cancer surveillance : automated image analysis to identify and monitor keratinocyte dysplasia / Hames, S.C.; Prow, T.W. -- Reflectance confocal microscopy : hallmarks of keratinocyte cancer and its precursors / Prow, T.W.; Tan, J.-M.; Pellacani, G. -- Optical coherence tomography and its role for delineating the thickness of keratinocyte dysplasia and neoplasia / Themstrup, L.; Jemec, G.B.E. -- Teledermatology : its use in the detection and management of actinic keratosis / Janda, M. -- Conventional treatment of actinic keratosis : an overview / Peris, K.; Fargnoli, M.C. -- Field cancerization : from molecular basis to selective field-directed management of actinic keratosis / Philipp-Dormston, W.G. -- Update on photodynamic treatment for actinic keratosis / Wiegell, S.R. -- Laser treatment and its implications for photodamaged skin and actinic keratosis / de Vries, K.; Prens, E.P. -- Ingenol mebutate : from common weed to cancer cure / Zarchi, K.; Jemec, G.B.E. -- Oral nicotinamide and actinic keratosis : a supplement success story / Kim, B.; Halliday, G.M.; Damian, D.L.
  • 2012 Springer
    Chen, Chang-Hwei.
  • 2012
    Hoover, Paul James; Dolmetsch, Ricardo E.; Lewis, Richard; Nachury, Maxence; Tsien, R. W.
    In excitable and non-excitable cells store-operated Ca2+ entry (SOCE) is a ubiquitous cellular mechanism that is critical for numerous processes such as gene expression, exocytosis, and metabolism. SOC channels are activated when stimulation of cell surface receptors initiates a signaling cascade leading to Ca2+ release from the endoplasmic reticulum (ER). ER Ca2+ release triggers activation of SOC channels in the plasma membrane (PM), the best characterized of which is the Ca2+ release-activated Ca2+ (CRAC) channel. An ER embedded protein, STIM1, acts as the ER Ca2+ sensor, and a tetramer of Orai1 subunits forms the pore of the active CRAC channel. After store depletion, STIM1 and Orai1 redistribute to sites of close apposition between the ER and the PM known as ER-PM junctions where they interact to produce Ca2+ entry. However, the fundamental question of how they interact to elicit Ca2+ entry was unknown. In our first line of inquiry, we show that the C-terminal polybasic domain of STIM1 targets STIM1 to ER-PM junctions independently of Orai1, that a cytosolic region of STIM1--CRAC activation domain (CAD)--binds directly to Orai1, that CAD is necessary and sufficient to cluster and activate CRAC channels, and that clustering and activation are functionally separable events. These results support a two-part diffusion trap mechanism for SOCE. After store depletion, STIM1 forms puncta independently of Orai1 underneath the PM where CAD is positioned to trap diffusing CRAC channels in the PM and induce a conformational change to activate channels. In the second line of inquiry we address the stoichiometric requirements for CRAC channel trapping and activation at ER-PM junctions. For this we developed a novel technique in single cells to control and measure the STIM1-Orai1 stoichiometry at ER-PM junctions while simultaneously recording channel activity. We find that binding of 1-2 STIM1s is sufficient to immobilize the tetrameric CRAC channel at ER-PM junctions but this fails to evoke significant activation, while binding of 8 STIM1s causes maximal CRAC channel activity. We also find that the extent of fast Ca2+-dependent inactivation parallels STIM1-CRAC channel stoichiometry. The data are well described by a modified Monod-Wyman-Changeux model where STIM1 binds to Orai1 with negative cooperativity and channels open with positive cooperativity due to stabilization of the open state by STIM1. These results suggest a highly nonlinear dependence of CRAC channel activation on STIM:Orai stoichiometry.
  • 2014 Springer
    Norman, Reid L.; Robert-McComb, Jacalyn J.; Zumwalt, Mimi.
    The purpose of the The Active Female: Health Issues Throughout the Lifespan, 2nd Edition is twofold: (1) to increase the awareness of wellness and fitness issues for active females and their family members; and (2) to provide an avenue for medical practitioners, allied health professionals, health educators, and certified individuals in sports medicine to gain critical, updated knowledge of a field specific to active females. Part I of the book offers a foundation to help the reader understand the interrelationship among body image concerns, the female reproductive cycle, and musculoskeletal anatomy/physiology of females that makes their health risks and concerns unique. Reproductive health is discussed by a prominent researcher in reproduction/endocrinology. An overview of the Female Athlete Triad which is a syndrome of three interrelated conditions (isordered eating, menstrual disturbances and bone loss) is presented in Part II. Physicians and certified professionals in sports medicine discuss the individual components of the triad, relating not only to the athletic female but also to the recreationally active woman throughout the lifespan. In Part III, Prevention and management of common musculoskeletal injuries is addressed by a female orthopedic surgeon who sub-specializes in treating female athletes. Finally, appropriate exercise and nutritional guidelines for active females are discussed in Parts IV-V of the book by certified professionals and licensed physicians in sports medicine. An invaluable addition to the literature, The Active Female: Health Issues Throughout the Lifespan, 2nd Edition will be of great interest to physicians, allied health care practitioners, medical/other wellness educators, and students who are interested in advancing women's health issues. Sports medicine specialists, family practitioners, gynecologists, team physicians, residents in sports medicine, athletic trainers, health educators, nurses, physicians assistants, physical therapists, sport psychologists, counselors, athletic trainers, and other members of the sports medicine team should also find this title of significant interest.
  • 2008 Springer
    Norman, Reid L.; Robert-McComb, Jacalyn J.; Zumwalt, Mimi.
    Pt.I: Focusing on active female's health issues: unique gender-related psychological and physiological characteristics of females -- Pt.II: Preoccupation with body image issues and disordered eating issues in the acitve female -- Pt.III: Reproductive health -- Pt.IV: Prevention and management of common musculoskeletal injuries in active females -- Pt.V: Safe exercise guidelines throughout the lifespan -- Pt.VI: Nutrition, energy balance, and weight control.
  • 2010 Karger
    Böheim, Klaus.
    The vibrant soundbridge : design and development / Ball, G.R. -- Cost-effectiveness of implantable middle ear hearing devices / Snik, A. ... [et al.] -- Indications and candidacy for active middle ear implants / Wagner, F. ... [et al.] -- Clinical results with an active middle ear implant in the oval window / Hüttenbrink, K.B., Beutner, D., Zahnert, T. -- Experiments on the coupling of an active middle ear implant to the stapes footplate / Zahnert, T., Bornitz, M., Hüttenbrink, K.B. -- The vibrant soundbridge for conductive and mixed hearing losses : European multicenter study results / Baumgartner, W.-D. ... [et al.] -- Clinical experience with the active middle ear implant vibrant soundbridge in sensorineural hearing loss / Pok, S.M., Schlögel, M., Böheim, K. -- The esteem system : a totally implantable hearing device / Maurer, J., Savvas, E. -- Totally implantable active middle ear implants : ten years' experience at the University of Tübingen / Zenner, H.P., Rodriguez Jorge, J.
  • 2007 Springer
    Fay, Richard R.; Manley, Geoffrey A.; Popper, Arthur N.
  • 2015
    Active Shooter events are becoming increasingly more common, and while there have been recommendations on how to respond since 2008, these guidelines focused on schools, government, and business settings. In January of 2014, the HPH SCC released "Active Shooter Planning and Response in a Healthcare Setting". That draft document was the first comprehensive guidance written for healthcare facilities to prevent, respond to, and recover from an active shooter event. This updated document expands upon the initial draft document to include law enforcement tactics and integrated medical and mental health response.
  • 2012 Springer
    Klotz, Laurence H.
  • v. 1, 1939.
    Soulié, Charles Georges.
    Status: Not Checked OutLane Catalog Record
    I. L'énergie (points, méridiens, circulation) -- II. Le maniement de l'énergie.
  • 2014 CRCnetBASE
    Dung, H. C.
    "The Chinese are known to have practiced acupuncture for approximately 2,000 years. Designed specifically for health care practitioners, this book demystifies acupuncture and explains it in anatomical terms. New emphasis is made to differentiate traditional acupuncture in Oriental medicine from scientific acupuncture, which is based entirely on medical sciences. This edition is completely updated and presents the most current research. New material includes information on how to quantify pain and a new way to define acute and chronic pain"--Provided by publisher.
  • 2012 Springer
    Cho, William C. S.
  • 2014 Springer
    Hsu, Eric S.; Lin, Yuan-Chi.
    Acupuncture for Pain Management is intended as the premier resource for learning the fundamentals of the art of medical acupuncture. Edited by top pain medicine specialists at Harvard and UCLA, and based on their popular annual workshop at the American Society for Anesthesiologists, the book is the perfect synthesis of Western and Chinese medicine. Anesthesiologists, pain medicine specialists, primary care physicians, osteopaths, neurologists, psychiatrists, physical medicine and rehabilitation specialists, and other health professionals looking to add acupuncture to their repertoire will benefit from the concise and practical approach of the book. Features: Each individual meridian discussed in detail acupuncture for 25 clinical conditions, including headache, menstrual pain, low back pain, insomnia, and more. Aimed at acupuncturists as well as practitioners who want to add acupuncture to their clinical armamentarium.
  • 2010 Springer
    Cao, Xiaoding; Cheng, Jieshi; Wu, Gencheng; Xia, Ying.
  • 2014 Springer
    Augustin, Goran.
    Part I. Surgery -- 1. Acute Appendicitis -- 2. Acute Biliary Tract Diseases -- 3. Acute Pancreatitis -- 4. Nontraumatic Gastroduodenal Perforations -- 5. Symptomatic Abdominal Wall Hernias -- 6. Symptomatic Diaphragmatic Hernia -- 7. Intestinal Obstruction -- 8. Acute Inflammatory Bowel Disease -- 9. Spleen -- 10. Abdominal Trauma -- 11. Miscellaneous Conditions -- Part II. Gynecology -- 12. Adnexal Torsion -- 13. (Isolated) Torsion of the Fallopian Tube -- 14. Ruptured/Bleeding Ovarian Cysts/Tumors -- 15. Ruptured Ectopic Pregnancy -- 16. Spontaneous Uterine Rupture -- 17. Torsion of the Gravid Uterus -- 18. Degenerating Uterine Myomas -- 19. Pelvic Inflammatory Disease and Tubo-ovarian Abscess.
  • 2013 Springer
    Chick, Grégoire.
    Neglected finger injuries may lead to chronic lesions that often have detrimental consequences for the practice of a ball sport, whether at a recreational level or at the top athlete level. The initial injury management is crucial. Depending on the type and the severity of the lesions, different people may get involved: the players themselves or their entourage, physiotherapists, club doctors, emergency physicians, family doctors, sports doctors or hand surgeons. Treatment is usually conservative: the long fingers require rapid mobilization to prevent stiffness and contrary to that, the thumb requires stability. Surgery may be necessary to reach these goals especially for athletes, because of the demands of their sport. Chronic lesions are also in part related to repeated trauma, requiring specialized long-term multidisciplinary treatment. They can often lead to the end of a sporting career, but also may limit the functionality of the fingers at the time of conversion.
  • 2014 Springer
    Varon, Joseph; Fromm, Robert E.
    This pocket guide is a single-volume source of the most common and important formulas and laboratory values used in the daily practice of acute care and critical care medicine. Information is presented in outline format and as tables, graphics, and algorithms to facilitate quick look up. Acute and Critical Care Formulas and Laboratory Values is designed to help clinicians interpret clinical data, apply formulas, understand laboratory values, and integrate this information with their knowledge of pathophysiology to promote the delivery of evidence-based care. Essential formulas and laboratory values. Multiple ways to derive a value, where appropriate. Non-clinical formulas useful for understanding physiologic concepts or that underlie diagnostic tests or clinical measurement.
  • 2010 Karger
    Hirasawa, Hiroyuki; Suzuki, Hiromichi.
    "Describes the use of hemodiafiltration to inhibit the cytokine storms which cause serious organ damage in patients with septic shock. Moreover, the technical construction of the blood purification system, which includes various machines, devices, membranes, fluids, etc., is explained in detail. Finally, leading experts discuss the concept of continuous renal replacement therapy as the standard care in critically ill patients with severe acute kidney injury."--Website.
  • 2008
    Bhardwaj, Anish; Ellegala, Dilantha B.; Kirsch, Jeffrey R.
    Status: Not Checked OutLane Catalog Record
    Decompressive hemicraniectomy for large hemispheric infarctions / Eric Jüttler, Alfred Aschoff, and Stefan Schwab -- Anticoagulation in ischemic stroke / Carolyn A. Cronin and Robert J. Wityk -- Angioplasty and stenting of cervical carotid, intracranial, and vertebral arteries / Aclan Dogan ... [et al.] -- Neuromonitoring in ischemic stroke / Kairash Golshani, Emun Abdu, and Anish Bhardwaj -- Surgical evacuation of intracerebral hemorrhage / Patrick C. Hsieh ... [et al.] -- Management of blood pressure and intracranial hypertension in intracerebral hemorrhage / Gustavo J. Rodríguez, Qaisar A. Shah, and Adnan I. Qureshi -- Decompressive hemicraniectomy in the management of severe traumatic brain injury / Ian F. Dunn and Dilantha B. Ellegala -- Cerebroprotective strategies in bedside management of traumatic brain injury / Ganesh M. Shankar, Ian F. Dunn, and Dong H. Kim -- Diffuse axonal injury and dysautonomia / Richard H. Singleton, David O. Okonkwo, and P. David Adelson -- Neuromonitoring in traumatic brain injury / Rene Celis and Claudia S. Robertson -- Hypothermia and pharmacologic coma in the treatment of traumatic brain injury / Gordon Li ... [et al.] -- Pediatric traumatic brain injury / Zachary N. Litvack and Nathan R. Selden -- Diagnostic evaluation of aneurysmal subarachnoid hemorrhage / Jonathan A. Edlow -- Surgical versus endovascular aneurysmal exclusion / Aaron W. Grossman, Anil V. Yallapragada, and Giuseppe Lanzino -- Diagnosis and medical management of vasospasm and delayed cerebral ischemia / Olga Helena Hernandez and Jose I. Suarez -- Pharmacologic cerebroprotection in aneurysmal subarachnoid hemorrhage / Yekaterina Axelrod, Salah Keyrouz, and Michael N. Diringer -- Use of anticonvulsants and corticosteroids in SAH / Panayiotis N. Varelas and Lotfi Hacein-Bey -- Management of electrolyte and metabolic derangements in subarachnoid hemorrhage / Tarik Hanane and Eelco F.M. Widjicks -- Management of cardiopulmonary dysfunction in subarachnoid hemorrhage / Thomas P. Bleck -- Neuroradiologic interventional procedures for cerebral vasospasm / Pascal M. Jabbour, Erol Veznedaroglu, and Robert H. Rosenwasser -- Intraoperative management of spinal cord injury / Dawn Dillman and Ansgar Brambrink -- Medical management of acute spinal cord injury / Steven Casha and R. John Hurlbert -- Pediatric spine injury / Brian Jankowitz, David O. Okonkwo, and Christopher Shaffrey.
  • 2014 Springer
    Capezuti, Liz; Malone, Michael L.; Palmer, Robert M.
    1. An Introduction to the Acute Care for Elders / Michael L. Malone, Ji Won Yoo, and James S. Goodwin -- 2. The Team Approach to Interdisciplinary Care / Maryjo Cleveland, Carolyn Holder, Ariba Khan, and Aileen Jencius -- 3. Patient and Hospital Factors That Lead to Adverse Outcomes in Hospitalized Elders / Edgar Pierluissi, Deborah C. Francis, and Kenneth E. Covinsky -- 4. An Overview of Hospital-Based Models of Care / Elizabeth A. Capezuti and Marie Boltz -- 5. The Acute Care for Elders Unit / Robert M. Palmer and Denise M. Kresevic -- 6. How to Develop, Start, and Sustain an Acute Care for Elders Unit / Ellen S. Danto-Nocton, Carolyn Holder, Rebecca Ramsden, Jonny Macias Tejada, Anita Steliga, and Karen Padua -- 7. How to Disseminate the ACE Model of Care Beyond One Unit / Roger Y. Wong, Marsha Vollbrecht, and Patti Pagel -- 8. How to Use the ACE Unit to Improve Hospital Safety and Quality for Older Patients: From ACE Units to Elder-Friendly Hospitals / Samir K. Sinha, Sandra Liliana Oakes, Selma Chaudhry, and Theodore T. Suh -- 9. ACE Unit Business Model / Kyle Allen, Peter DeGolia, Susan Hazelett, and Diane Powell -- 10. Models of Care to Transition from Hospital to Home / Ella Harvey Bowman, Kellie L. Flood, and Alicia I. Arbaje -- 11. What Is the Role of Hospitalists in the Acute Care for Elders? / Heidi L. Wald and Melissa L. P. Mattison -- 12. How to Improve Care for Seniors in the Emergency Department / Soryal Soryal, Marie Boltz, Scott Wilber, and Michael L. Malone -- 13. How to Improve Care for Older Patients in the Intensive Care Unit / Leanne Boehm, E. Wesley Ely, and Lorraine Mion -- 14. The Future of Acute Care for Elders / Kanwardeep Singh and Michael L. Malone.
  • 2014 ScienceDirect
    Paz, Jaime C.; West, Michele P.
    Part 1. Introduction -- 1. Acute Care Setting -- 2. The Medical Record -- Part 2. Body Systems -- 3. Cardiac System --4. Pulmonary System -- 5. Musculoskeletal System -- 6. Nervous System -- 7. Vascular System and Hematology -- 8. Gastrointestinal System -- 9. Genitourinary System -- 10. Endocrine System -- Part 3. Diagnoses -- 11. Oncology -- 12. Burns and Wounds -- 13. Infectious Diseases -- 14. Organ Transplantation -- 15. Fluid and Electrolyte Imbalances -- 16. Amputation -- 17. Physical Therapy Considerations for Patients Who Complain of Chest Pain -- Part 4. Interventions -- 18. Medical-Surgical Equipment in the Acute Care Setting -- 19. Pharmacologic Agents -- 20. Anesthesia: Perioperative Considerations for the Physical Therapist -- 21. Acute Pain Management -- 22. Postural Drainage -- 23. Functional Tests -- Appendix A. Preferred Practice Patterns.
  • 2009
    Chernecky, Cynthia C.; Murphy-Ende, Kathleen.
    Status: Not Checked OutLane Catalog Record
    Acute pancreatitis / Jean Ellsworth-Wolk -- Acute respiratory distress syndrome / Mercedes K. Young -- Malignant ascites / Deborah Murphy -- Bronchitis obliterans / Laura Milligan and Yvonne D. Martin -- Cardiac tamponade and pericardial effusions / Brenda K. Shelton -- Carotid artery rupture / Catherine Sargent -- Cognitive dysfunction / Nancy Jo Bush -- Depression and anxiety / Nancy Jo Bush -- Diabetes insipidus / Jennifer U. Varma -- Diabetes mellitus / Timothy L. Wren and Kathleen R. Wren -- Disseminated intravascular coagulation (DIC) / Brenda K. Shelton -- Dyspnea and airway obstruction / Cynthia C. Chernecky and Libby Montoya -- End-of-life care / Cynthia Brown and Kathleen Murphy-Ende -- Esophageal varices / Lori Ann Brown -- Ethics in adult oncology and critical care nursing / Marlene M. Rosenkoetter -- Fever / Angela L. Daniel -- Gastrointestinal obstruction : biliary, gastric, and bowel obstructions / Kathleen Murphy-Ende -- Graft versus host disease / Jill K. Burleson -- Heart failure / Jacqueline R. Gannuscio -- Hemorrhage secondary to cervical cancer / Brenda K. Cobb and Cynthia C. Chernecky -- Hemorrhagic cystitis / Cathy Fortenbaugh -- Hepatic encephalopathy / Kathleen Murphy-Ende -- Tumor-induced hypercalcemia / Kathryn E. Pearson -- Hyperkalemia / Mary Pat Lynch -- Hyperleukocytosis in childhood leukemia / Kristin Casey -- Hypernatremia / Mady Stovall -- Hypersensitivity reactions to chemotherapy / Teresa Kuntzsch and Cassie A. Voge -- Hyperurecemia / Libby Montoya -- Hypokalemia / Mary Pat Lynch -- Hypomagnesemia / Lyle Stuart Baker, Jr., Brenda K. Shelton, and Michael I. Agugo -- Hyponatremia / Cynthia C. Chernecky, Demica N. Jackson, and Angela L. Daniel -- Increased intracranial pressure / Kara L. Penne -- Lactic acidosis, type B / Catherine Sargent -- Lambert-Eaton myasthenic syndrome / Dionne T. Savage -- Malnutrition and cachexia / Kathy G. Kravits and Marcia Grant -- Pain management : nociceptive and neuropathic / Christine Miaskowski -- Pathological fractures / Cynthia C. Chernecky -- Pleural effusions : malignant / Diane G. Cope -- Pulmonary fibrosis / Cynthia C. Chernecky -- Seizures / Mary P. Lovely -- Sepsis and septic shock / Kathy A. Shane -- Sinusoid occlusive syndrome / Patricia C. Buchsel -- Spinal cord compression / Christine Miaskowski -- Spiritual distress in people with cancer / Martha Meraviglia, Carol D. Gaskamp, and Rebecca R. Sutter -- Suicidal ideation / Kathleen Murphy-Ende -- Superior vena cava syndrome / Molly Loney and Nancy Kelly -- Syndrome of inappropriate antidiuretic hormone (SIADH) / Jeanne Held-Warmkessel -- Tumor lysis syndrome / Brenda K. Shelton -- Typhlitis in pediatrics / Kaci L. Osenga.
  • 2007 Springer
    Britt, L. D.; Feliciano, David V.; Trunkey, Donald D.
    Part I. General Principles -- Initial Assessment and Early Resuscitation / Louis H. Alarcon and Andrew B. Peitzman -- The Operating Theater for Acute Care Surgery / Kenneth L. Mattox -- Anesthesia and Acute Care Surgery / Omid Moayed and Richard P. Dutton -- Fundamental Operative Approaches in Acute Care Surgery / David J. Ciesla and Ernest E. Moore -- The Perioperative Management of the Acute Care Surgical Patient / Craig M. Coopersmith and Timothy G. Buchman -- The Hemodynamically Labile Patient: Cardiovascular Adjuncts and Assist Devices / Edward E. Cornwell and Preeti R. John -- Principles and Practice of Nutritional Support for Surgical Patients / Maheswari Senthil, Bobby Rupani, Jondavid H. Jabush and Edwin A. Deitch -- The Intensive Care Unit: The Next-Generation Operating Room / Philip S. Barie, Soumitra R. Eachempati and Jian Shou -- Burns / Basil A. Pruitt and Richard L. Gamelli -- Electrical and Lightning Injuries / Raphael C. Lee -- Soft Tissue Infections / Anthony A. Meyer, Jeffrey E. Abrams, Thomas L. Bosshardt and Claude H. Organ -- The Open Abdomen: Management from Initial Laparotomy to Definitive Closure / Fred A. Luchette, Stathis J. Poulakidas and Thomas J. Esposito -- Acute Care Surgery and the Elderly / Patrick K. Kim, Donald R. Kauder and C. William Schwab -- Acute Care Surgery in the Rural Setting / Dana Christian Lynge, Nicholas W. Morris and John G. Hunter -- Prehospital Care in the Acute Setting / Norman E. McSwain -- Disaster and Mass Casualty Management / Eric R. Frykberg -- Principles of Injury Prevention and Control / M. Margaret Knudson and Larisa S. Speetzen -- Education: Surgical Simulation in Acute Care Surgery / Lenworth M. Jacobs and Karyl J. Burns -- Part II. Organ-Based Approach -- Pharynx and Larynx / Ernest M. Myers -- Head and Neck: Pediatrics / Reza Rahbar and Gerald B. Healy -- Esophagus / George C. Velmahos, Nahid Hamoui, Peter F. Crookes and Demetrios Demetriades -- Central Nervous System / Peter B. Letarte -- Chest Wall / John C. Mayberry and Donald D. Trunkey -- Lungs and Pleura / Riyad Karmy-Jones and J. Wayne Meredith -- Heart / Matthew S. Slater -- Thoracic Aorta / Peter I. Ellman and Irving L. Kron -- Diaphragm / Michel B. Aboutanos, Therèse M. Duane, Ajai K. Malhotra and Rao R. Ivatury -- Abdominal Wall / Jeffrey A. Claridge and Martin A. Croce -- Foregut / Philip E. Donahue -- Small Intestine / Juliet Lee, Todd Ponsky and Jeffrey L. Ponsky -- Liver and Biliary Tract / Spiros P. Hiotis and Hersch L. Pachter -- Pancreas / Juan A. Asensio, Patrizio Petrone and L. D. Britt -- Spleen / L. D. Britt -- Intraabdominal Vasculature / George H. Meier and Hosam F. El Sayed -- Colon and Rectum / Herand Abcarian -- Urogenital Tract / Nejd F. Alsikafi, Sean P. Elliott, Maurice M. Garcia and Jack W. McAninch -- Pelvis / Craig M. Rodner and Bruce D. Browner -- Lower Extremities / Tina A. Maxian and Michael J. Bosse -- Hand and Upper Extremities / David T. Netscher and Idris Gharbaoui -- Peripheral Vasculature / David V. Feliciano -- Part III. Administration, Ethics, and Law -- Understanding the Latest Changes in EMTALA: Our Country's Emergency Care Safety Net / Thomas R. Russell -- Informed Surgical Consent / Linda S. Laibstain and Robert C. Nusbaum -- Advance Directives / David G. Jacobs -- The Nonviable Patient and Organ Procurement / Frederic J. Cole, Jay N. Collins and Leonard J. Weireter -- Ethical Dilemmas and the Law / Ira J. Kodner, Daniel M. Freeman, Robb R. Whinney and Douglas J. E. Schuerer -- Part IV. System and Curriculum Development -- Development of a Regional System for Surgical Emergencies (RSSE) / A. Brent Eastman, David B. Hoyt and J. Wayne Meredith -- Acute Care Surgery: A Proposed Curriculum / L. D. Britt and Michael F. Rotondo -- Emergency General Surgery: The Vanderbilt Model / José J. Diaz, Oscar D. Guillamondegui and John A. Morris -- Part V. The International Communities -- Acute Care Surgery: United Kingdom / Bernard F. Ribeiro, Simon Paterson-Brown, Murat Akyol, Michael Walsh and Andrew Sim, et al. -- Acute Care Surgery: Australia / Thomas Kossmann and Ilan S. Freedman -- Acute Care Surgery: Japan / Kyoichi Takaori and Nobuhiko Tanigawa.
  • 2015 AccessSurgery
    Butler, Kathryn L.; Harisinghani, Mukesh G.
    Section I. Radiology basics -- Section II. Abdomen -- Section III. Chest -- Section IV. Soft tissue -- Section V. Trauma.
  • 2015 Springer
    Eachempati, Soumitra R.; Reed, R. Lawrence.
  • 2008 Springer
    Herzog, Eyal; Hong, Mun K.
  • 2011 ClinicalKey
    Théroux, Pierre.
    Acute Coronary Syndromes-a Companion to Braunwald₂s Heart Disease-covers the state-of-the-art scientific and clinical information you need to rapidly evaluate and manage acute coronary syndromes. Dr. Pierre Theroux and his team of expert contributors present advances in diagnostic and imaging techniques such as biomarkers, nuclear cardiology, echocardiography, and multislice CT; secondary prevention; and new antiplatelet, anti-ischemic, and gene therapies. Tap into the most definitive knowledge available from one of the leading experts in the field and a stellar cast of contributors. Understand the special considerations for the care of acute coronary syndromes in the emergency department and the coronary care unit. Effectively handle the treatment of special populations and chronic patients thanks to coverage of these challenges.
  • 2005 HighWire
    Bolognese, Leonardo; Ferrari, Roberto.
    Also available: Print – 2005
  • 2008 Springer
    Berghe, Greet Van den.
  • 2008 Springer
    Gheorghiade, M.; Mebazaa, Alexandre; Parrillo, Joseph E.; Zannad, F.
    Also available: Print – 2008
  • 2009 Springer
    Krüger, Wolfgang; Ludman, Andrew.
  • 2005 HighWire
    Gheorghiade, M.; Zannad, F.
    Also available: Print – 2005
  • 2006 Springer
    González, R. G.
  • 2011 Springer
    González, R. G.; Hirsch, Joshua A.; Lev, Michael H.; Schaefer, Pamela W.; Schwamm, Lee H.
  • 2007. Karger
    Bellomo, R.; Kellum, John A.; Ronco, C.
    Also available: Print – 2007
  • 2016 Karger
    Ding, Xiaoqiang; Ronco, C.
    Acute kidney injury epidemiology : from recognition to intervention / Wang, Y., Fang, Y., Teng, J., Ding, X. -- Acute kidney injury prevention / Chopra, T.A., Brooks, C.H., Okusa, M.D. -- Renal recovery after acute kidney injury / Macedo, E., Mehta, R.L. -- Pathophysiology of septic acute kidney injury / Mårtensson, J., Bellomo, R. -- Biomarkers for diagnosis, prognosis and intervention in acute kidney injury / Fuhrman, D.Y., Kellum, J.A. -- The acute kidney injury to chronic kidney disease transition : a potential opportunity to improve care in acute kidney injury / Palant, C., Amdur, R., Chawla, L.S. -- Electronic data systems and acute kidney injury / Cheungpasitporn, W., Kashani, K. -- Fluid management in acute kidney injury / Chuang, C.-L. -- Multidimensional approach to adequacy of renal replacement therapy in acute kidney injury / Villa, G., Ricci, Z., Romagnoli, S., Ronco, C. -- Timing of renal replacement therapy in acute kidney injury / Ostermann, M., Wald, R., Bagshaw, S.M. -- Pediatric continuous renal replacement therapy / Ricci, Z., Goldstein, S.L. -- Management of cardiac surgery-associated acute kidney injury / Ding, X., Xu, J., Jiang, W., Fang, Y., Teng, J.
  • OHR
  • 2008 HighWire
    Dudek, Dariusz.
  • 2014 Springer
    Kerkhoffs, Gino M.M.J; Servien, Elvire.
  • 2007 Springer
    Karp, Judith E.
    Approaching the treatment of AML from a biological perspective : an overview / Farhad Ravandi and Francis Giles -- Aberrant transcription factors in AML / Alan D. Friedman -- Myelodysplasia-related AML / Jane E. Parker -- Therapy-related AML / Lucy A. Godley and Michelle Le Beau -- The DNA damage response, DNA repair, and AML / David P. Steensma -- Altered apoptosis in AML : potential implications for pathogenesis and therapeutic response / Ruben A. Mesa and Scott H. Kaufmann -- Drug resistance transporters in AML / Douglas D. Ross -- Impact of cytogenetics on clinical outcome in AML / David Grimwade -- APL : a classic tale of bench to bedside / Olga Frankfurt ... [et al.] -- Emerging therapeutics for AML / Edward A. Sausville -- FLT3 : a prototype receptor tyrosine kinase target in AML / Mark Levis -- Farnesyl transferase inhibitors in the therapy of AML / Jeffrey E. Lancet -- Modulating gene expression as a therapeutic approach in the treatment of AML / Tamer Fandy, Hetty Carraway, and Steven D. Gore -- Differentiation therapy in AML / Tara L. Lin and William Matsui -- Stem cell transplantation for AML / Javier Bolaños-Meade and Richard J. Jones -- Tumor vaccines in leukemia / Ivan Borrello -- Treatment, outcomes, and challenges of newly diagnosed AML in children and adolescents / Robert J. Arceci -- AML in older adults / Richard M. Stone -- Dameshek smiles : molecular clues to the chronic myeloproliferative disorders unmasked / Jason Gotlib -- New designs for clinical trials / Elihu Estey.
    Also available: Print – 2007
  • 2010 Springer
    Nagarajan, Lalitha.
    Also available: Print – 2010
  • 2015 Springer
    Straaten, Heleen M. Oudemans-van.
    This practical guide provides the reader with answers to important clinically relevant questions regarding the evaluation and management of acute kidney injury (AKI). All aspects of critical care nephrology are covered, from pathophysiology and diagnosis to prevention and treatment. The questions considered relate to a wide range of issues, such as: How do I diagnose AKI? How can I protect the kidney in clinical practice? How do I manage patients with AKI? When should I initiate and how do I perform renal replacement therapy (RTT)? Which type of RTT is most appropriate for my patient? Should I give specific nutrients? In addition to providing practical guidelines and treatment algorithms, the book includes calculators for continuous RRT and anticoagulant dosing. The authors are internationally renowned experts in the fields of Intensive Care Medicine and Nephrology, and all contributions are written in a clear and concise style and have been peer reviewed. Acute Nephrology for the Critical Care Physician will serve as a very useful source for intensivists, internists, anesthesiologists, and nephrologists involved in the management and treatment of critically ill patients at risk of or affected by AKI.
  • 2010 Springer
    Fujikawa, Denson G.
  • 2014 Springer
    Sejersen, Thomas; Wang, Ching H.
    This book provides recommendations for evaluation and therapy in the area of acute pediatric neurology; these are presented didactically with frequent use of illustrations and algorithms. Chapters in the first part of the book discuss presenting symptoms of acute neurological conditions. The second part of the book covers major areas of acute pediatric neurology and each of these chapters has three key elements: description of presenting symptoms; recommended assessments; and recommended interventions. Acute Pediatric Neurology provides an accessible, clinically focused guide to assist physicians in the emergency ward or intensive care unit in decisions on diagnosis and therapeutic interventions in all major acute pediatric neurological diseases.
  • 2007 Springer
    Pandolfi, P. P.; Vogt, Peter K.
    APL as a paradigm in biomedical research : a journey toward the cure / P.P. Pandolfi -- Mouse models of acute promyelocytic leukemia / S.C. Kogan -- The PLZF gene of t(11;17)-associated APL / M.J. McConnell and J.D. Licht -- SUMO, the three Rs and cancer / J.-S. Seeler ... [et al.] -- Emerging role for microRNAs in acute promyelocytic leukemia / C. Nervi ... [et al.] -- The theory of APL revisited / P.P. Scaglioni and P.P. Pandolfi -- Treatment of acute promyelocytic leukemia by retinoids / P. Fenaux, Z.Z. Wang, and L. Degos -- Arsenic trioxide and acute promyelocytic leukemia : clinical and biological / Z. Chen ... [et al.] -- Front line clinical trials and minimal residual disease monitoring in acute promyelocytic leukemia / F. Lo-Coco and E. Ammatuna -- Histone deacetylase inhibitors in APL and beyond / K. Petrie, N. Prodomou, and A. Zelent -- Monoclonal antibody therapy of APL / P.G. Maslak, J.G. Jurcic, and D.A. Scheinberg -- Targeting APL fusion proteins by peptide interference / A. Melnick -- The design of selective and non-selective combination therapy for acute promyelocytic leukemia / Y. Jing and S. Waxman.
    Also available: Print – yyyy
  • 2010
    Choi, Augustine M. K.
    Status: Not Checked OutLane Catalog Record
    Definitions and clinical risk factors / Moss, Thompson -- Epidemiology of acute lung injury : a public health perspective / Rubenfeld -- Radiographic findings of the acute respiratory distress syndrome / Goodman, Quiñones -- Pulmonary pathology of ARDS : diffuse alveolar damage / Kobzik, Sholl -- Pathogenesis of acute lung injury : experimental studies / Baron, Perrella -- Pathogenesis of acute lung injury : clinical studies / Creagh-Brown, Evans -- Apoptosis in the pathogenesis and resolution of the acute lung injury / Matute-Bello, Martin -- Pathogenesis of ventilator-induced lung injury / Valenza, Frank, Imai, Slutsky -- Sepsis in the acute respiratory distress syndrome : treatment implications / Wheeler, Rice -- Transfusion related acute lung injury / Looney, Gajic -- Mechanisms of fibroproliferation in acute lung injury / Morse, Feghali-Bostwick -- Current approaches and recent advances in the genetic epidemiology of acute lung injury/acute respiratory distress syndrome / Gong, Christiani -- Gene expression profiling and biomarkers in ARDS / Howrylak, Choi -- Resolution of alveolar edema : mechanisms and relaltionship to clinical acute lung injury / Ware, Matthay -- Lung vascular dysfunction and repair in acute lung injury : role of the endothelial cytoskeleton / Lang, Chiang, Garcia -- Surfactant therapy in the acute respiratory distress syndrome / Spragg, Lewis -- Prone position in ARDS / Anzueto, Gattinoni -- Mechanical ventilation in the acute respiratory distress syndrome / Brower, Brochard -- Fluid therapy and hemodynamic monitoring in acute lung injury / Calfee, Gupta, Matthay -- Pathogenesis of sSepsis and septis-induced acute lung injury / Harris ... [et al.] -- Cell-based therapy for acute lung injury and acute respiratory distress syndrome / Gupta, Lee, Matthay -- Chemokines and cytokines in ARDS / Keane, Kelly, Streiter.
  • 2013
    Bochner, David; Clandinin, Thomas R.; Knudsen, Eric I.; Luo, Liqun; Shatz, Carla J.
    Neural plasticity is high during developmental critical periods, then declines by adulthood. Here by acutely disrupting PirB function at different ages, we show that Paired immunoglobulin like receptor B (PirB) actively restricts plasticity both during and after the critical periopd. Chapter 1 introduces ocular dominance (OD) plasticity as a model of circuit and synaptic change, and presents a review of the literature on the study of mechanisms of OD plasticity, critical period timing, and manipulations that can alter plasticity later in life. Chapter 2 presents an overview of the methodological approaches used. PirB function was disrupted with temporal precision via either a conditional PirB allele or by minipump infusion of a soluble PirB ectodomain into mouse visual cortex. Chapter 3 details the effects of disrupting PirB function on plasticity in healthy animals. OD plasticity is enhanced not only during the critical period, but also when PirB function is disrupted in adulthood. The effects of adult deletion can occur even when PirB is only lost in excitatory neurons of the forebrain. Acute blockade of PirB for 10 days after the close of the critical period increases spine density on apical and basolateral dendrites of Layer 5 pyramidal neurons. Chapter 4 presents a proof of concept for therapeutic disruption of PirB function in cases of neurological dysfunction and disease. Long term monocular deprivation (LTMD) during the critical period leads to a lasting loss of vision in the deprived eye and to a decrease in dendritic spine density that does not recover even with subsequent binocular vision. However, acute blockade of PirB following LTMD allows for full recovery of spine density. MeCP2308/y mice, a mouse model of Rett Syndrome (a syndromic autism), were found to have increased MHC Class I expression and a concurrent loss of OD plasticity during the critical period, which can be rescued by acute blockade of PirB. Taken together, these results imply that mechanisms for enhanced structural and functional plasticity are present in adult visual cortex but are actively repressed by PirB. By removing negative regulators such as PirB, we show that it is possible to engage these endogenous mechanisms to facilitate recovery from otherwise irreversible effects of dysfunctional development. Our observations suggest that similar manipulations may be useful in other situations where restoring synaptic plasticity and increasing spine density have therapeutic value.
  • 2007
    Bhardwaj, Anish.
    Status: Not Checked OutLane Catalog Record
  • 2012 Karger
    Lamprecht, Manfred.
    Beta-alanine supplementation in high-intensity exercise / Harris, R.C., Sale, C. -- Arginine and citrulline supplementation in sports and exercise : ergogenic nutrients / Sureda, A., Pons, A. -- Dietary nitrate and O2 consumption during exercise / Jones, A.M., Bailey, S.J., Vanhatalo, A. -- GABA supplementation and growth hormone response / Powers, M. -- Exercise, intestinal barrier dysfunction, and probiotic supplementation / Lamprecht, M., Frauwallner, A. -- Pleuran (glucan from pleurotus ostreatus) : an effective nutritional supplement against upper respiratory tract infections / Majtan, J. -- Bovine colostrum and immune function after exercise / Davison, G. -- Supplementation with mixed fruit and vegetable concentrates in relation to exercise, performance and sport : scientific insight and practical relevance / Lamprecht, M. -- Cherry juice targets antioxidant potential and pain relief / Kuehl, K.S. -- Impact of milk consumption and resistance training on body composition of female athletes -- Josse, A.R., Phillips, S.M. -- Glycerol use in hyperhydration and rehydration : scientific update -- Van Rosendal, S.P., Coombes, J.S. -- Salt and fluid loading : effects on blood volume and exercise performance / Mora-Rodriguez, R., Hamouti, N. -- Milk protein and the restoration of fluid balance after exercise / James, L. -- Chocolate milk : a post-exercise recovery beverage for endurance sports / Pritchett, K., Pritchett, R. -- Role of supplementary l-carnitine in exercise and exercise recovery / Huang, A., Owen, K. -- Supplements and inadvertent doping : how big is the risk to athletes? / Judkins, C., Prock, P.
  • 2014 AccessMedicine
    Ropper, Allan H.; Adams, Raymond D.; Klein, Joshua; Samuels, Martin A.; Victor, Maurice.
    Ch. 1. Approach to the patient with neurologic disease -- Ch. 2. Imaging, electrophysiologic, and laboratory techniques for neurologic diagnosis -- Ch. 3. Motor paralysis -- Ch. 5. Ataxia and disorders of cerebellar function -- Ch. 6. Tremor, myoclonus, focal dystonias, and tics -- Ch. 7. Disorders of stance and gait -- Ch. 10. Headache and other craniofacial pains -- Ch. 11. Pain i n the back, neck, and extreities -- Ch. 12. Disorders of smell and taste -- Ch. 13. Disturbances of vision -- Ch. 14. Disorders of ocular movement and pupillary function -- Ch. 15. Deafness, dizziness, and disorders of equilibrium -- Ch. 16. Epilepsy and other seizure disorders -- Ch. 17. Coma and related disorders of consciousness -- Ch. 18. Faintness and syncope -- Ch. 19. Sleep and its abnormalities -- Ch. 20. Delirium and other acute confusional states.
  • 2009 AccessMedicine
    Ropper, Allan H.; Adams, Raymond D.; Samuels, Martin A.; Victor, Maurice.
    Approach to the patient with neurologic disease -- Special techniques for neurologic diagnosis -- Motor paralysis -- Abnormalities of movement and posture caused by disease of the basal ganglia -- Incoordination and other disorders of cerebellar function -- Tremor, myoclonus, focal dystonias, and tics -- Disorders of stance and gait -- Pain -- Other somatic sensation -- Headache and other craniofacial pains -- Pain in the back, neck, and extremities -- Disorders of smell and taste -- Disturbances of vision -- Disorders of ocular movement and pupillary function -- Deafness, dizziness, and disorders of equilibrium -- Epilepsy and other seizure disorders -- Coma and related disorders of consciousness -- Faintness and syncope -- Sleep and its abnormalities -- Delirium and other acute confusional states -- Dementia and the amnesic (korsakoff) syndorme with comments on the neurology of intelligence and memory -- Neurologic disorders caused by lesions in specific parts of the cerebrum -- Disorders of speech and language -- Fatigue, asthenia, anxiety, and depressive reactions -- The limbic lobes and the neurology of emotion -- Disorders of the autonomic nervous system, respiration, and swallowing -- The hypothalamus and neuroendocrine disorders -- Normal development and deviations in development of the nervous system -- The neurology of aging -- Disturbances of cerebrospinal fluid and its circulation, including hydrocephalus, pseudotumor cerebri, and low-pressure syndromes -- Intracranial neoplasms and paraneoplastic disorders -- Infections of the nervous system (bacterial, fungal, spirochetal, parasitic) and sarcoidosis -- Viral infections of the nervous system chronic meningitis, and prion diseases -- Cerebrovascular diseases -- Craniocerebral trauma -- Multiple sclerosis and allied demyelinating diseases -- Inherited metabolic diseases of the nervous system -- Developmental diseases of the nervous system -- Degenerative diseases of the nervous system -- The acquired metabolic disorders of the nervous system caused by nutritional deficiency -- Alcohol and alcoholism -- Disorders of the nervous sytem caused by drugs, toxins, and other chemical agents -- Diseases of the spinal cord -- Electrophysiologic and laboratory aids in the diagnosis of neuromuscular disease -- Diseases of the peripheral nerves -- Diseases of the cranial nerves -- Principles of clinical myology: diagnosis and classification of disease of muscle and neuromuscular junction -- The infectious and inflammatory myopathies -- The muscular dystrophies -- The metabolic and toxic myopathies -- The congenital neuromuscular disorders -- Myasthenia gravis and related disorders of the neuromuscular junction -- Ion channel disorders: the periodic paralyses and hereditary nondystrophic myotonias (channelopathies) -- Disorders of muscle characterized by cramp, spasm, pain, and localized masses -- The anxiety neuroses, hysteria, and personality disorders -- Depression and bipolar disease -- The schizophrenias and paranoid states.
    Also available: Print – 2009
  • 2012 CRCnetBASE
    Chin, Richard Y.
    1. Background -- 2. Conventional statistics -- 3. Statistics used in adaptive clinical trials -- 4. Specific requirements for adaptive trials -- 5. Adaptive randomization and allocation -- 6. Sample size reestimation -- 7. Traditional dosing -- 8. Adaptive dosing -- 9. Interim analysis and adaptive termination of study and study arms -- 10. Adaptive changes in study design and decision rules -- 11. Seamless designs and adaptive clinical trial conduct -- 12. Analysis and interpretation of results.
  • 2013 Springer
    Laviola, G.; Macrì, Simone.
    1. The Inductive Agency of Stress: From Perinatal to Adolescent Induction / Trevor Archer and Richard M. Kostrzewa -- Part I. Introductory Concepts -- 2. Making Sense of Stress: An Evolutionary-Developmental Framework / Marco Del Giudice, Bruce J. Ellis, and Elizabeth A. Shirtcliff -- 3. Prenatal and Maternal Psychosocial Stress in Primates: Adaptive Plasticity or Vulnerability to Pathology? / Dario Maestripieri and Amanda C.E. Klimczuk -- Part II. Adaptive and Maladaptive Consequences of Developmental Stress In Humans -- 4. The Everyday Stress Resilience Hypothesis: Unfolding Resilience from a Perspective of Everyday Stress and Coping / Jennifer A. DiCorcia, Akhila V. Sravish, and Ed Tronick -- 5. Ontogeny of Stress Reactivity in the Human Child: Phenotypic Flexibility, Trade-Offs, and Pathology / Mark V. Flinn, Davide Ponzi, Pablo Nepomnaschy, and Robert Noone -- 6. Consequences of Developmental Stress in Humans: Prenatal Stress / Nadine Skoluda and Urs M. Nater -- 7. Consequences of Developmental Stress in Humans: Adversity Experienced During Childhood and Adolescence / Urs M. Nater and Nadine Skoluda -- Part III. Adaptive and Maladaptive Consequences of Developmental Stress in Animal Models -- 8. Behavioural and Neuroendocrine Consequences of Prenatal Stress in Rat / Sara Morley-Fletcher, Jérôme Mairesse, and Stefania Maccari -- 9. Developmental Consequences of Prenatal Administration of Glucocorticoids in Rodents and Primates / Jonas Hauser -- 10. Early Developmental Trajectories of Brain Development: New Directions in the Search for Early Determinants of Health and Longevity / F. Cirulli and A. Berry -- 11. Adaptive Regulations in Developing Rodents Following Neonatal Challenges / Laurence Coutellier -- 12. Adaptive and Maladaptive Regulations in Response to Environmental Stress in Adolescent Rodents / Simone Macrì and Giovanni Laviola -- 13. Oxidative Stress and Hormetic Responses in the Early Life of Birds / David Costantini.
  • 2013
    Granka, Julie Marie; Feldman, Marcus W.; Fraser, Hunter B.; Petrov, Dmitri A.; Tang, Hua.
    Organismic evolution involves both selective and neutral forces, although their relative contributions are often unknown. This thesis proposes novel statistical methods for analyzing genetic data from a variety of organisms, including yeast, Mycobacterium tuberculosis, and humans. The chapters of this thesis provide complimentary perspectives on the relative roles of selection and neutrality, from the molecular to the population level, and present various statistical tools for genetic data analysis. Chapter 2 proposes a maximum-likelihood based method with which to classify and identify interactions, or epistasis, between pairs of genes. Chapter 3 details a study of genetic data from Mycobacterium tuberculosis isolated from human Aboriginal Canadian communities; our analyses suggest that the bacterium spread to these communities via the Canadian fur trade in the 18th and 19th centuries. Chapter 4 discusses the detection of signatures of natural selection in the genomes of 12 diverse African human populations, and proposes novel considerations for identifying biological functions under selection and for comparing signals of selection between populations. Finally, Chapter 5 details the inference of the genetic basis and evolutionary history of light skin pigmentation and short stature in the genetically diverse [not equal to sign]Khomani Bushmen of the Kalahari Desert of South Africa, believed to be one of the world's most ancient human populations. These chapters emphasize that a more complete understanding of the evolutionary history of humans and other organisms requires not only the consideration of neutral and selective processes, but also both phenotypic and genetic information. The statistical methods and approaches presented in the following chapters have the potential to improve inferences of natural selection and demography from genetic data, as well as provide insight into the relative roles of both.
  • Click LINK above for Print location/circulation status.
    2007 CRCnetBASE
    Chow, Shein-Chung; Chang, Mark.
  • 2012 CRCnetBASE
    Chow, Shein-Chung; Chang, Mark.
    Protocol amendment -- Adaptive randomization -- Adaptive hypotheses -- Adaptive dose-escalation trials -- Adaptive group sequential design -- Statistical tests for adaptive seamless designs -- Adaptive sample size adjustment -- Two-stage adaptive design -- Adaptive treatment switching -- Bayesian approach -- Biomarker adaptive trials -- Target clinical trials -- Sample size and power estimation -- Clinical trial simulation -- Regulatory perspectives : a review of FDA draft guidance.
  • 2012
    Liao, Yueh-Wen; Lai, T. L.; Lavori, Philip W.; Shih, Mei-Chiung.
    When developing new drugs, Phase I and II trials are commonly conducted to determine the dose of the new treatment in preparation for the subsequent confirmatory Phase III trial. However, because these early-phase trials usually do not have large enough sample sizes to decide which dosage level or treatment regimen is the best, several of them may arise as candidates for the confirmatory Phase III trial. Conventional fixed sample size designs that carry out all the treatment arms of interest are obviously expensive. Therefore, the pharmaceutical industry is increasingly interested in adaptive designs that can use information acquired during the course of the trial to update certain of the design features. In this thesis we explore several existing designs and discuss their pros and cons. We then propose one that shares the flexibility of Bayesian adaptive designs, while still being able to maintain the frequentist type I error probability. We develop an asymptotic theory for efficient outcome-adaptive randomization schemes and optimal stopping rules. Our approach consists of developing asymptotic lower bounds for the expected sample sizes from the treatment arms and the control arm, and using generalized sequential likelihood ratio procedures to achieve these bounds. These allow us to allocate patients and study resources efficiently by using outcome-adaptive randomization schemes, or by arm suspension/selection if fixed randomization is used. We also derive an adaptive test with a p-value that can be evaluated by Monte Carlo simulation based on an ordering scheme of the sample space. We then show that the approach can also be applied to the closely related problem of multi-stage testing of multiple hypotheses.
  • 2007
    Bergan, Joseph Fossland.
    Status: Not Checked OutLane Catalog Record
  • 2012 CRCnetBASE
    Murphy, Martin J.
    "Preface External-beam radiotherapy has long been vexed by the simple fact that patients can (and do) move during the delivery of radiation. The most elegant and forward-looking solution to this reality is to actively adapt the radiation delivery process to the patient's natural movements. Recent advances in imaging and beam delivery technologies have now made this solution a practical reality. The purpose of this book is to present to researchers and clinical practitioners in radiation therapy an overview of the current and prospective state of the art in motion-adaptive radiation therapy. It presents technical reviews of each of the contributing elements of a motion-adaptive system (including target detection and tracking, beam adaptation, and patient realignment), discusses treatment planning issues that arise when the patient and internal target are mobile, describes several integrated motion-adaptive systems that are in clinical use or at advanced stages of development, and concludes with a review of the system control functions that must be an essential part of any therapy device that operates in a near-autonomous manner with limited human interaction. From these chapters, the reader will hopefully gain not only an understanding of the technical aspects and capabilities of motion adaptation but also practical clinical insights into planning and carrying out various types of motion-adaptive radiotherapy treatment"--Provided by publisher.
  • 2013 CRCnetBASE
    Kubby, Joel A.
    Adaptive Optics for Biological Imaging brings together groundbreaking research on the use of adaptive optics for biological imaging. The book builds on prior work in astronomy and vision science. Featuring contributions by leaders in this emerging field, it takes an interdisciplinary approach that makes the subject accessible to nonspecialists who want to use adaptive optics techniques in their own work in biology and bioengineering.Organized into three parts, the book covers principles, methods, and applications of adaptive optics for biological imaging.
  • 2011 CRCnetBASE
    Li, X. Allen.
  • 2008 Springer
    Nagarajan, Srikatan S.; Sekihara, Kensuke.
  • Google Books
    Also available: Print – 1981-
  • 2008 CRCnetBASE
    Karch, Steven B.
    The Principles of addiction medicine / Duncan Raistrick -- Substitute prescribing : opioid-specific prescribing / Kim Wolff -- Substitute prescribing : buprenorphine maintenance prescribing / Nick Lintzeris -- Treatment of withdrawal symptoms / Joanna Banbery -- Replacement prescribing / Kim Wolff -- Management of comorbidity / Duncan Raistrick -- Toxicologic issues / Kim Wolff -- Medical aspects of drug abuse / Shoshana Zevin and Neal L. Benowitz -- Emergency management of drug abuse / Brett A. Roth, Neal L. Benowitz, and Kent R. Olson.
  • 2011 Springer
    Johnson, Bankole A.
    This book attempts to "bridge the gap between the explosion of neuroscientific and behavioral knowledge in the past three decades and treatment delivery in clinical practice. As such, it should fulfill the role of a comprehensive textbook that integrates addiction medicine from its scientific underpinnings to the treatment of patients in clinical settings"--Preface, p. vii.
  • 2012 ScienceDirect
    Carter, Adrian; Hall, Wayne; Illes, Judy.
    What is addiction neuroethics and why does it matter? -- Brain Imaging in Addiction -- Molecular Neuroscience and Genetics -- Treating Opioid Dependence with Opioids: Exploring the Ethics -- Addiction Neuroscience and Tobacco Control -- Emerging Neurobiological Treatments of Addiction: Ethical and Public Policy Considerations -- Technical, Ethical and Social Issues in the Bioprediction of Addiction Liability and Treatment Response -- Autonomy, Responsibility and the Oscillation of Preference -- Consent and Coercion in Addiction Treatment -- Toward a Lay Descriptive Account of Identity in Addiction Neuroethics -- The Impact of Changes in Neuroscience and Research Ethics on the Intellectual History of Addiction Research -- The Diction of Addiction at the Intersection of Law and Neuroscience -- Social Epistemology: Communicating Neuroscience -- Population Approaches to Alcohol, Tobacco and Drugs: Effectiveness, Ethics and Interplay with Addiction Neuroscience -- Legal Regulation of Addictive Substances and Addiction -- Investment and Vested Interests in Neuroscience Research of Addiction: Ethical Research Requires More than Informed Consent -- Private and Public Approaches to Addiction Treatment: Evidence and Beliefs.
  • 2011 Springer
    Kelly, John F.; White, William L.
    Addiction Recovery Management: Theory, Research, and Practice is the first book on the recovery management approach to addiction treatment and post-treatment support services. Distinctive in combining theory, research, and practice within the same text, this ground-breaking title includes authors who are the major theoreticians, researchers, systems administrators, clinicians and recovery advocates who have developed the model. State-of-the art and the definitive text on the topic, Addiction Recovery Management: Theory, Research, and Practice is mandatory reading for clinicians and all professionals who work with patients in recovery or who are interested in the field.
  • 2015
    McDaniel, Marla.
    This brief offers strategies for service providers in public or assisted housing communities to develop strong home visiting services for highly distressed families battling challenges such as depression, substance abuse, or domestic violence. It also provides information on one strategy in particular--the SCRIPT model--that gives concrete instructions for better serving families' mental health and other needs in home visiting programs. The brief also offers insights into how the model's framework could be adapted to allow local communities to respond to their community's particular needs, challenges, and contexts.
  • 2013 Springer
    Saitz, Richard.
    "While there is a wealth of published information on addiction medicine, the psychological aspects of alcohol abuse, and behavioral medicine with regard to addiction, virtually none of the existing resources were written with the primary care provider in mind. Addressing Unhealthy Alcohol Use in Primary Care is a handy reference for primary care clinicians who are confronted by patients with these problems daily, and who wish to successfully address these issues in their practice. Focusing on the literature and science relevant to practicing providers, this book covers the range of interventions appropriate for this setting. Topics include assessment, brief counseling interventions, pharmacotherapy, referrals to both specialty care and Alcoholics Anonymous (and other self-help programs), psychiatric comorbidity and other drug use, and other information specific to the needs of the primary care clinician. The vast majority of people with health risks and consequences related to alcohol use receive little to no attention from healthcare, despite the fact that alcohol is a leading cause of early preventable death. This book is a guide to identifying and addressing unhealthy alcohol use in hopes of improving the lives of patients."--publisher's website
  • 2011 Future Med
    Bermel, Robert A.; Rudick, Richard A.
    Addressing unmet medical needs in RR-MS / Robert A. Bermel & Richard A. Rudick -- Current guidelines and standard treatments of RR-MS / R. Philip Kinkel & Augusto Miravalle -- Oral agents for the treatment of RR-MS / Douglas R. Jeffery -- Monoclonal antibodies / Jennifer Graves & Emmanuelle L. Waubant -- Other therapeutics in the pipeline and future directions / Yuval Karmon, Bijal K. Mehta & Bianca Weinstock-Guttman.
  • 2011 Springer Protocols
    Moullier, Philippe; Snyder, Richard O.
    Adeno-associated virus biology / Matthew D. Weitzman and R. Michael Linden -- Design and construction of functional AAV vectors / John T. Gray and Serge Zolotukhin -- AAV capsid structure and cell interactions / Mavis Agbandje-McKenna and Jürgen Kleinschmidt -- Exploring natural diversity of AAV for the design of vectors with novel properties / Guangping Gao, Li Zhong, and Olivier Danos -- Gene therapy in skeletal muscle mediated by adeno-associated virus vectors / Chunping Qiao ... [et al.] -- AAV mediated liver-directed gene therapy / Mark S. Sands -- Recombinant AAV delivery to the central nervous system / Olivier Bockstael ... [et al.] -- Adeno-associated virus mediated gene therapy for retinal degenerative diseases / Knut Steiger ... [et al.] -- Adeno-associated virus vector delivery to the heart / Lawrence T. Bish ... [et al.] -- Evaluation of the fate of rAAV genomes following in vivo administration / K. Reed Clark and Magalie Penaud-Budloo -- Measuring immune responses to recombinant AAV gene transfer / Ashley T. Martino ... [et al.] -- Modificaton and labeling of AAV vector particles / Hildegard Büning ... [et al.] -- AAV mediated gene targeting / Daniel G. Miller -- Preclinical study design for rAAV / Terence R. Flotte, Thomas J. Conlon, and Christian Mueller -- Biodistribution and shedding of AAV vectors / Caroline Le Guiner, Phillipe Moullier, and Valder R. Arruda -- Production and purification of recombinant adeno-associated vectors / Lijun Wang ... [et al.] -- rAAV vector product characterization and stability studies / Richard O. Snyder, Muriel Audit, and Joyce D. Francis -- rAAV human trial experience / Katherine A. High and Patrick Aubourg.
  • 2010 Springer
    Schneider, Paul M.
  • 2013 Springer
    Boison, Detlev; Masino, Susan.
    Adenosine and Metabolism--A Brief Historical Note / Bertil B. Fredholm -- Adenosine Metabolism, Adenosine Kinase, and Evolution / Jaoek Park and Radhey S. Gupta -- Adenosine and Energy Metabolism--Relationship to Brain Bioenergetics / Xuesong Chen, Liang Hui and Jonathan D. Geiger -- Adenosine and Autocrine Metabolic Regulation of Neuronal Activity / Masahito Kawamura Jr. and David N. Ruskin -- Physiologic and Metabolic Regulation of Adenosine: Mechanisms / Chris G. Dulla and Susan A. Masino -- The Double-Edged Sword: Gaining Adenosine at the Expense of ATP. How to Balance the Books / Stephanie zur Nedden, Alexander S. Doney and Bruno G. Frenguelli -- Downstream Pathways of Adenosine / Ana M. Sebastião, Sofia Cristóvão-Ferreira and Joaquim A. Ribeiro -- Astrocytic ATP Release / Dustin J. Hines and Philip G. Haydon -- Role of Striatal A2A Receptor Subpopulations in Neurological Disorders / Sergi Ferré, César Quiroz, Marco Orrú, Xavier Guitart and Seema Gulyani, et al. -- Sleep and Adenosine: Human Studies / Tarja Porkka-Heiskanen -- Adenosine and Other Purinergic Products in Circadian Timing / Christine Muheim and Steven A. Brown -- Adenosine in the Immune System / György Hask, Balázs Koscsó́ and Balázs Csóka -- The Bioenergetic Network of Adenosine in Hibernation, Sleep, and Thermoregulation / Kelly L. Drew and Tulasi R. Jinka -- Adenosine and Stroke / Felicita Pedata, Anna Maria Pugliese, Francesca Corti and Alessia Melani -- The Many Roles of Adenosine in Traumatic Brain Injury / Patrick M. Kochanek, Jonathan D. Verrier, Amy K. Wagner and Edwin K. Jackson -- Therapeutic Perspectives of Adenosine Receptor Compounds in Functional Restitution After Spinal Cord Injury / Kwaku D. Nantwi -- Adenosine and Pain / Jana Sawynok -- Symptomatic and Neuroprotective Effects of A2A Receptor Antagonists in Parkinson's Disease / Annalisa Pinna, Nicola Simola, Lucia Frau and Micaela Morelli -- Adenosine Receptors and Alzheimer's Disease / David Blum, Ursula Sandau, Cyril Laurent, Vânia Batalha and Antoine Leboucher, et al. -- Adenosine Receptors in Huntington's Disease / David Blum, Alberto Martire, Sylvie Burnouf, Bernard Sablonnière and Pierre Krystkowiak, et al. -- Adenosine and Multiple Sclerosis / Maria Victoria Sánchez-Gómez, Estibaliz González-Fernández, Rogelio O. Arellano and Carlos Matute -- Adenosinergic Perspectives on Schizophrenia: Opportunity for an Integrative Synthesis / Benjamin K. Yee, Philipp Singer and Detlev Boison -- The Role of Adenosine in the Ventral Striatal Circuits Regulating Behavioral Activation and Effort-Related Decision Making: Importance for Normal and Pathological Aspects of Motivation / John D. Salamone, Merce Correa, Patrick A. Randall, Eric J. Nunes and Marta Pardo, et al. -- Adenosine and Autism: Physiological Symptoms and Metabolic Opportunities / Julia Svedova, Inge-Marie Eigsti and Susan A. Masino -- Stress, Brain Adenosine Signaling, and Fatigue-Related Behavioral Processes / Traci N. Plumb, Sarah R. Sterlace, Kelly A. Cavanaugh and Thomas R. Minor -- Disruption of Adenosine Homeostasis in Epilepsy and Therapeutic Adenosine Augmentation / Detlev Boison -- Ketogenic Diet and Epilepsy: The Role of Adenosine / Jong M. Rho, Beth Zupec-Kania and Susan A. Masino -- Silk: A Biocompatible and Biodegradable Biopolymer for Therapeutic Adenosine Delivery / Eleanor M. Pritchard, Detlev Boison and David L. Kaplan -- Anatomical Distribution of Nucleoside System in the Human Brain and Implications for Therapy / Zsolt Kovács and Arpád Dobolyi.
  • 2012 Springer
    Samuel, Charles E.
    ADAR proteins : structure and catalytic mechanism / Rena A. Goodman, Mark R. Macbeth and Peter A. Beal -- ADAR proteins : double-stranded RNA and Z-DNA binding domains / Pierre Barraud and Frédéric H.-T. Allain -- Editing of neurotransmitter receptor and ion channel RNAs in the nervous system / Jennifer L. Hood and Ronald B. Emeson -- Modulation of microRNA expression and function by ADARs / Bjorn-Erik Wulff and Kazuko Nishikura -- Nuclear editing of mRNA 3'-UTRs / Ling-Ling Chen and Gordon G. Carmichael -- Control of ADAR1 editing of hepatitis delta virus RNAs / John L. Casey -- Bioinformatic approaches for identification of A-to-I editing sites / Eli Eisenberg -- ADARs : viruses and innate immunity / Charles E. Samuel -- Role of ADARs in mouse development / Carl R. Walkley, Brian Liddicoat and Jochen C. Hartner -- Regulation and functions of ADAR in Drosophila / Simona Paro, Xianghua Li, Mary A. O'Connell and Liam P. Keegan.
  • 2007 CRCnetBASE
    Cronstein, Bruce N.; Haskó, György; Szabó, Csaba.
  • 2009 Springer
    Abbracchio, M. P.; Mustafa, S. Jamal; Wilson, Constance N.
  • 2015 Springer
    Morelli, Micaela; Simola, Nicola; Wardas, Jadwiga.
  • 2012 Springer
    Tabery, Helena M.
    pt. 1. Adenovirus epithelial keratitis -- pt. 2. Thygeson's superficial punctate keratitis.
  • v. 1-2, 2006. Springer Protocols
    v. 2, 2006 Springer Protocols
    Tollefson, Ann E.; Wold, William S. M.
    v. 1. Adenoviruses, ad vectors, quantitation, and animal models -- v. 2. Ad proteins and RNA, lifecycle and host interactions, and phylogenetics.
  • 2014 Springer Protocols
    Bosch, Assumpció; Chillón, Miguel.
    Biophysical methods to monitor structural aspects of the adenovirus infectous cycle / Rosa Menéndez-Conejero ... [et al.] -- Proteome analysis of adenovirus using mass spectrometry / Sara Bergström Lind, Konstantin A. Artemenko, and Ulf Pettersson -- Capsid modification strategies for detargeting adenoviral vectors / Alan L. Parker ... [et al.] -- Use of dodecahedron "VLPs" as an alternative to the whole adenovirus / Pascal Fender -- Study of adenovirus and CAR axonal transport in primary neurons / Charleine Zussy and Sara Salinas -- The use of chromatin immunoprecipitation (hIP) to study the binding of viral proteins to the adenovirus genome in vivo / Yueting Zheng and Patrick Hearing -- DNA microarray to analyze adenovirus-host interactions / Stefania Piersanti, Enrico Tagliafico, and Isabella Saggio -- Determination of the transforming activities of adenovirus oncogenes / Thomas Speiseder, Michael Nevels, and Thomas Dobner -- Oncolytic adenovirus characterization : activity and immune responses / Raul Gil-Hoyos, Juan Miguel-Camacho, and Ramon Alemany -- The analysis of innate immune response to adenovirus using antibody arrays / Nelson C. Di Paolo and Dmitry M. Shayakhmetov -- Engineering adenovirus genome by bacterial artificil chromosome (BAC) technology / Zsolt Ruzsics, Frederic Lemnitzer, and Christian Thirion -- Construction, production, and purification of recombinant adenovirus vectors / Susana Miravet ... [et al.] -- Sealable production of adenovirus vectors / Ana Carina Silva ... [et al.] -- Canine adenovirus downstream processing protocol / Meritxell Puig ... [et al.] -- Production of high-capacity adenovirus vectors / Florian Kreppel -- Production of chimeric adenovirus / Marta Miralles ... [et al.]
  • 2013 Springer
    Koziol, Leonard F.; Budding, Deborah Ely; Chidekel, Dana.
    Neuroscience, Neuropsychology, and Attention-Deficit Hyperactivity Disorder: ADHD as a Model of Brain-Behavior Relationships -- ADHD, Attention, and DSM Diagnosis: History and Context -- ADHD and Neuropsychological Nomenclature -- Diagnostic Systems and Etiological Models -- Neuropsychological Models of Attention and ADHD -- Broad-Based Neuropsychological Test Batteries and ADHD -- Preliminary Answers to the Question -- Dimensional Approaches for Evaluating Disorders: Research Domain Criteria -- The Neocortex, Regional Functional Specialization, and Cognitive Networks -- Large-Scale Brain Networks and Functional Connectivity -- The Ontogeny of Functional Brain Networks -- Large-Scale Brain Network Disturbances in ADHD -- The Selection Problem -- The Basal Ganglia -- The Basal Ganglia and Intention Programs -- The Basal Ganglia: Focused Attention and Learning Through Integrative Networks -- Reward Circuitry and the Basal Ganglia -- The Cerebellum -- The Modular Organization of the Cerebellum -- The Development of Motor Skills, Executive Functions, and a Relationship to ADHD: A Preliminary Review -- Revisiting Neuropsychological Testing and the Paradox of ADHD -- Neural Network Dynamics: How Large-Scale Brain Networks Interact -- Concluding Remarks.
  • 2013 Springer
    Surman, Craig.
    ADHD in Adults: A Practical Guide to Evaluation and Management is the product of a unique collaboration of international specialists. This volume offers easy-to-read guidance, and includes checklists, rating scales and treatment planning tools. It was designed for a broad audience of caregivers working in diverse settings, including psychiatrists, social workers, primary care physicians, nurse specialists and psychologists. The authors are highly acclaimed clinicians, investigators and educators. They offer step-by-step guidance for implementation of best practices, drawing from clinical research and their experience treating thousands of patients. They cover diagnosis, treatment planning, and state-of-the-art application of pharmacology, psychotherapy, skill-building, family system and environmental interventions - for both simple and complex cases. The scales and worksheets in this Guide were developed to efficiently facilitate assessment and management. The Editor is an international leader in the field from the Clinical and Research Program in Adult ADHD at Massachusetts General Hospital (MGH) and Harvard Medical School, which has made pioneering and highly cited contributions to the understanding of ADHD. This Guide is a definitive, indispensable resource for all health providers who wish to optimize their approach to adult patients with ADHD.
  • 2014 Springer
    Fleischhacker, W. W. (W. Wolfgang); Sacchetti, Emilio; Vita, Antonio.
    Poor adherence to therapy is one of the main obstacles to treatment effectiveness in schizophrenia. It is the main determinant of relapse, hospitalization, symptom persistence, and poor psychosocial functioning and outcome. Adherence to treatment is affected by various factors related to the disease characteristics, to the patient him- or herself, to the treatment, and to the therapeutic relationship. Some of these factors are modifiable, and both pharmacological and non-pharmacological strategies have been developed for this purpose.This book addresses the different aspects of adherence to treatment in schizophrenia and related disorders in a systematic but easy-to-use manual format. Chapters focus on a full range of issues, including pharmacological and non-pharmacological strategies to enhance adherence and continuity of care, relevant psychological factors, the importance of the patient-doctor relationship, and the need for an alliance with other care-givers. Adherence to Antipsychotics in Schizophrenia will be an invaluable asset for all who are involved in the care of patients with schizophrenia.
  • 2010 Springer
    Rapoff, Michael A.
    Definitions of adherence, types of adherence, problems, and adherence rates -- Consequences of nonadherence and correlates of adherence -- Adherence theories: review, critique, and clinical implications -- Measurement issues: assessing adherence and disease and health outcomes -- Strategies for improving adherence to pediatric medical regimens -- Review of adherence intervention studies and top ten ways to advance research on adherence to pediatric medical regimens.
  • 2012 Springer
    Harris, Tony.
    Introduction to adherens junctions: from molecular mechanisms to tissue development and disease -- How AJs evolved -- Evolution of the cadherin-catenin complex -- How cadherins and catenins interact to assemble AJs -- Three-dimensional structure of the cadherin-catenin complex -- Biophysics of cadherin adhesion -- Adherens junction assembly -- How AJs interface with other cellular machinery -- Cytoskeleton and classical cadherin adhesions -- Immunoglobulin superfamily receptors and adherens junctions -- Signaling from the adherens junction -- Adherens junction turnover: regulating adhesion through cadherin endocytosis, degradation, and recycling -- How AJs affect cell behaviour and multicellular development -- Adherens junctions during cell migration -- Adherens junctions and cadherins in Drosophilia development -- Adherens junctions in C. elegans embryonic morphogenesis -- Cadherin function during xenopus gastrulation -- Adherens junctions in mammalian development, homeostasis and disease: lessons from mice -- How AJs affect tissue homeostasis and disease -- Adherens junctions and stem cells -- Adherens junctions and cancer -- Adherens junctions and pathogen entry.
  • 2006 CRCnetBASE
    Lacombe, Robert.
  • 2010 CRCnetBASE
    Preedy, Victor R.
    Adhesion molecules are a family of proteins located on the cell surface and are involved in cell-to-cell or cell-extracellular matrix binding. They have a role in maintaining the cellular integrity of tissues and the functional viability of organs. In many diseases the normative features of adhesion molecules are perturbed. Thus, understanding how adhesion molecules behave in health and disease is a key step in the advancement of science and health in general. In the first part of the hook, chapters cover the structure and classification of adhesion molecules, immunohistochemical localization, junctional and inflammatory adhesion molecules and molecular imaging. The other four parts of the book cover adhesion molecules in relation to signalling pathways, gene expression, arginine, stem cells, neutrophil migration, leukocytes, decompression sickness, ischemia reperfusion injury, diabetes, obesity, metabolic syndrome, weight loss, hypoxia, kidney disease, smoking, osteoprotegerin, tumors, biointormatics, high-throughput technologies, chemotherapy, hematopoiesis, lipoproteins, fatty acids, atrial fibrillation and heart disease, brain and dementia. The book is an essential book for research scientists, pathologists, molecular biologists, biochemists or cellular biochemists, clinicians, health care professionals, general practitioners as well as those interested in disease in general.
  • 2007 Springer
    Ley, Klaus.
    Also available: Print – 2007
  • 2007 Springer Protocols
    Coutts, Amanda S.
  • 2013 Springer Protocols
    Coutts, Amanda S.
  • 2010 Springer
    Stacey, Martin; Yona, Simon.
    The adhesion GPCRs : gene repertoire, phylogeny, and evolution / Helgi B. Schith, Karl J.V. Nordstrom, and Robert Fredriksson -- Cadherins : developmental roles and future challenges / Caroline J. Formstone -- Latrophilin signalling in tissue polarity and morphogenesis / Tobias Langenhan and Andreas P. Russ -- GPS proteolytic cleavage of adhesion-GPCRs / Hsi-Hsien Lin ... [et al.] -- The latrophilins : "split-personality" receptors / John-Paul Silva and Yuri A. Ushkaryov -- Studies on the very large G protein-coupled-receptor : from initial discovery to determining its role in sensorineural deafness in higher animals / D. Randy McMillan and Perrin C. White -- Adhesion-GPCRs in the CNS / Natalie Strokes and Xianhua Piao -- GPR56 interacts with extracellular matrix and regulates cancer progression / Lei Xu -- Adhesion-GPCRs in tumorigenesis / Gabriela Aust -- Immunity and adhesion-GPCRs / Simon Yona, Hsi-Hsien Lin, and Martin Stacey -- CD97 in leukocyte trafficking / Jorg Hamann ... [et al.] -- The role of CD97 in regulating adaptive T-cell responses / Ian Spendlove and Ruhcha Sutavani -- F4/80 : the macrophage specific adhesion-GPCR and its role in immunoregulation / Hsi-Hsien Lin ... [et al.] -- Signal transduction mediated through adhesion-GPCRs / Norikazu Mizuno and Hiroshi Itoh -- Emerging roles of brain specific angiogenesis inhibitor 1 / Daeho Park and Kodi S. Ravichandran -- Adhesion-GPCRs in the male reproductive tract / Ben Davies and Christiane Kirchhoff.
    Also available: Print – 2010
  • 2011 Springer
    Rovensky, Yury A.
    Extracellular matrix -- Cytoskeleton -- Pseudopodia and adhesion structures -- Adhesive interactions of tissue cells with the extracellular matrix -- Cell migration -- Cell responses to chemical heterogeneity of substrata: adhesive islets or paths -- Topographic cell responses -- Intercellular adhesive interactions.
  • 2012 CRCnetBASE
    Hunter, Ross J.; Preedy, Victor R.
    1. Acylation stimulating protein (ASP) as an adipokine / Thea Scantlebury-Manning -- 2. Adiponectin as an adipokine / Zhikui Wei and G. William Wong -- 3. Adipsin as an adipokine / Yu-Feng Zhao and Chen Chen -- 4. Adrenomedullin as a cytokine / Alexis Elias Malavazos and Gianluca Iacobellis -- 5. Angiotensinogen as an adipokine / Miki Nagase and Toshiro Fujita -- 6. Apelin as an adipokine / Despina D. Briana and Ariadne Malamitsi-Puchner -- 7. C1q/TNF-related proteins (CTRPs) as adipokines / Jonathan M. Peterson and G. William Wong -- 8. Fasting-induced adipose factor/angiopoietin-like protein 4 as an adipokine / Sander Kersten -- Interleukins as adipokines / Kirsten Prüfer Stone -- Leptin as an adipokine: important definitions and applications for cancer research / Barbara Stadterman [and others] -- Omentin as an adipokine: role in health and disease / Anne M. Lenz and Frank Diamond -- Plasminogen activator inhibitor 1 (Pai-1) as an adipokine / Francis Agyemang-Yeboah -- Resistin as an adipokine / Zhikui Wei and G. William Wong -- Retinol-binding protein 4 as an adipokine / Elmar Aigner and Christian Datz -- TNF-α as an adipokine / Theron C. Gilliland, Jr. and G. William Wong -- Transforming growth factor as an adipokine / Yutaka Yata and Terumi Takahara -- Vaspin as an adipokine: a link between obesity and metabolic alterations / Peter Kovacs, Matthias Blüher, and Gabriela Aust -- Visfatin as an adipokine / Ariadne Malamitsi-Puchner and Despina D. Briana -- Thermal stress and adipokines expression / Umberto Bernabucci, Patrizia Morera, and Loredana Basiricò -- Central nervous system roles for adiponectin in neuroendocrine and autonomic function / Ted D. Hoyda, Willis K. Samson, and Alastair V. Ferguson -- The astroglial leptin receptors and obesity / Weihong Pan [and others] -- Adipokines and obesity / Alberto O. Chavez and Devjit Tripathy -- Nonalcoholic fatty liver disease and adipokines / Stergios A. Polyzos, Jannis Kountouras, and Christos Zavos -- Endocrine disruptors, adipokines, and the metabolic syndrome / Eric R. Hugo and Nira Ben-Jonathan -- Adipokines and the heart / Gianluca Iacobellis -- Adipokines as mediators of rheumatic disease / Deborah M. Levy and Earl D. Silverman -- Adipokines and allergy / Giorgio Ciprandi [and others] -- Adipokines and sleep disorders / Kapil Dhawan [and others] -- Adipokines in children and adolescents and implications for disease / HuiLing Lu and Katherine Cianflone -- Role of leptin in immune cell development and innate immunity / Pamela J. Fraker and Afia Naaz -- Visfatin and hypocaloric diets / D.A. de Luis and R. Aller -- Apelin in energy metabolism / Isabelle Castan-Laurell and Philippe Valet -- Adiponectin deficiency / Wayne Bond Lau [and others] -- Adiponectin enhances inflammation in rheumatoid synovial fibroblasts and chondrocytes / Natsuko Kusunoki, Kanako Kitahara, and Shinichi Kawai -- Resistin, imflammation and seminal fluid / Uwe Paasch [and others] -- Resistin in amniotic fluid / Shali Mazaki-Tovi [and others].
  • 2011 Springer
    Illouz, Yves-Gérard; Sterodimas, Aris.
    Cellular and Molecular Aspects of Adipose Tissue -- Isolation of Stem Cells from Human Adipose Tissue: Technique, Problems, and Pearls -- Principles of Liposuction -- Clinical Applications of Liposuction -- Principles of Autologous Fat Transplantation -- Clinical Applications of Autologous Fat Transplantation -- Adipose Stem Cells: From Liposuction to Adipose Tissue Engineering -- Storage of Adipose Stem Cells -- Engineered Scaffolds and Matrices: Tailored Biomaterials for Adipose Stem Cell Engineering -- Fundamentals and Principles of Biomolecules in Adipose Stem Cell Engineering -- Gene Therapy Used for Adipose Stem Cell Engineering -- Stem Cells from Human Adipose Tissue: A New Tool for Pharmacological Studies and for Clinical Applications -- Role of Adipose Stem Cells Therapy in Obesity -- Stem Cell Based Cardioregeneration and Adipose Tissue -- Adipose Stem Cell Engineering: Characterization and Current Application in Neurological Tissue Repair -- Adipose Stem Cell Engineering: Clinical Applications in Plastic and Reconstructive Surgery -- Orthopedic Use of Adipose-Derived Stem Cells -- Adipose-Derived Stem Cells: Characterization and Application in Urology -- Adipose Stem Cell Engineering: Characterization and Current Application in Otolaryngology -- Adipose Stem Cell Technologies for Tissue Regeneration in Dentistry -- Adipose Stem Cells, Tissue Engineering, and Solid Organ Transplantation and Regeneration -- Industrial Approaches to Adipose Stem Cells Engineering -- Future Research in Adipose Stem Cell Engineering -- Conclusions and Future Directions.
  • 2007 Springer
    Fantuzzi, Giamila; Mazzone, Theodore.
    The adipose organ / Saverio Cinti -- Metabolism of white adipose tissue / Michel Beylot -- Leptin / Malaka B. Jackson and Rexford S. Ahima -- Adiponectin / Aimin Xu, Yu Wang, and Karen S.L. Lam -- Vasoactive factors and inflammatory mediators produced in adipose tissue / Gema Frohbeck -- Regulation of the immune response by leptin / Victor Sanchez-Margalet ... [et al.] -- Leptin in autoimmune disease / Giuseppe Matarese -- Leptin and gastrointestinal inflammation / Arvind Batra and Britta Siegmund -- Adiponectin and inflammation / Yuji Matsuzawa -- Macrophages, adipocytes, and obesity / Anthony W. Ferrante, Jr. -- Interactions of adipose and lymphoid tissues / Caroline M. Pond -- Adipose tissue and mast cells: adipokines as Yin-Yang modulators of inflammation / George N. Chaldakov ... [et al.] -- Bone marrow adipose tissue / Patrick Laharrague and Louis Castella -- Environmental aspects of obesity / Lisa Diewald, Myles S. Faith, and Meredith S. Dolan -- The genetics of obesity: five fundamental problems with the famine hypothesis / John R. Speakman -- Developmental perspectives on the origins of obesity / Cristopher W. Kuzawa, Peter D. Gluckman, and Mark A. Hanson -- The epidemiology of obesity / Carol A. Braunschweig -- Inherited and acquired lipodystrophies: disorders of adipose tissue, development, differentiation, and death / Vinaja Simha and Anil Agarwal -- Mechanisms of cachexia / Robert H. Mak and Wai W. Cheung -- Adipose tissue and insulin resistance / Stephen E. Borst -- Adipokines in non-alcoholic fatty liver disease / Ancha Baranova and Zobair M. Younossi -- Adiposity and cancer / Eugenia E. Calle -- Obesity and cardiovascular disease / Alison M. Morris, Paul Poirier, and Robert H. Eckel -- Obesity and asthma / Elisabeth Luder -- Adiposity and kidney disease / Srinivasan Beddhu and Bonnie Ching-Ha Kwan -- Obesity and joint disease / Andrew J. Teichtahl, Anita E. Wluka, and Flavia M. Cicuttini -- Effect of weight loss on disease / Sergio Jose Bardaro, Dennis Hong, and Lee Swanstrom.
  • 2014 Springer
    Fantuzzi, Giamila; Mazzone, Theodore.
    The field of adipose tissue biology has been expanding at a very rapid pace in the last few years. Numerous advances have been made since publication of the first edition of this book, in terms of basic adipocyte biology, understanding of the determinants of obesity, distribution of body fat and weight loss, as well as the mechanisms linking excess adiposity to various co-morbidities. Adipose Tissue and Adipokines in Health and Disease, Second Edition contains updated chapters from the previous volume but as the field has evolved, some areas covered in the first edition have been refocused to address the new knowledge. The volume is divided in four sections: the first two deal with basic adipose tissue and adipokine biology, while the last two address the problem of obesity and alterations in adipose tissue function from an epidemiological and clinical standpoint. The chapters are written by experts in their fields and include the most up to date scientific information. Adipose Tissue and Adipokines in Health and Disease, Second Edition is a useful resource for physicians interested in adipose tissue biology and basic scientists who want to know more about applied aspects of the field. The book targets endocrinologists, residents and fellows, internists, nutritionists and general practitioners who are exposed to an ever-expanding obese population.
  • 2013 Springer
    Kolonin, Mikhail G.
    Preface: Obesity, Adipose Tissue and Cancer Progression -- Metabolic Perturbations Associated with Adipose Tissue Dysfunction and the Obesity-Cancer Link -- Increased Adiposity and Colorectal Cancer -- Adiposity and Diabetes in Breast and Prostate Cancer -- Increased Adipocity and Endometrial Cancer Risk -- Adipokines: Soluble Factors from Adipose Tissue Implicated in Cancer -- Animal Models to Study the Interplay between Cancer and Obesity -- Unraveling the local influence of tumor-surrounding adipose tissue on tumor progression: cellular and molecular actors involved -- Trafficking of Cells from Adipose Tissue to Tumor Microenvironment -- The Impact of Obesity Intervention on Cancer: Clinical Perspectives -- Index.
  • 2012 Springer
    Symonds, Michael E.
    1. Adipocyte Precursors: Developmental Origins, Self-Renewal, and Plasticity / Christian Dani and Nathalie Billon -- 2. Adipocyte Differentiation / José María Moreno-Navarrete and José Manuel Fernández-Real -- 3. Brown Adipose Tissue / Martin Klingenspor and Tobias Fromme -- 4. White Adipose Tissue / Stephane Gesta and C. Ronald Kahn -- 5. Sex Differences in Body Fat Distribution / Alain Veilleux and André Tchernof -- 6. Macrophages and Inflammation / Elise Dalmas, Joan Tordjman, Michèle Guerre-Millo, and Karine Clément -- 7. Adipocyte Growth and Factors Influencing Adipocyte Life Cycle / Srujana Rayalam and Clifton A. Baile -- 8. The Evolution of Mammalian Adipose Tissue / Caroline M. Pond -- 9. Dietary Determinants of Fat Mass and Body Composition / María A. Zulet, María J. Moreno-Aliaga, and J. Alfredo Martínez -- 10. The Genetic Determinants of Common Obesity-Susceptibility / Ruth J.F. Loos -- 11. Early Origins of Obesity and Developmental Regulation of Adiposity / Shalini Ojha and Helen Budge.
  • 2010 Karger
    Levy-Marchal, C.; Pénicaud, Luc.
    Human lipodystrophies : genetic and acquired diseases of adipose tissue / Capeau, J. ... [et al.] -- The emergence of adipocytes / Laharrague, P.; Casteilla, L. -- Adipose tissue and the reproductive axis : biological aspects / Hausman, G.J.; Barb, C.R -- Unraveling the obesity and breast cancer links : a role for cancer-associated adipocytes? / Dirat, B. ... [et al.] -- Early determinants of obesity / Ong, K -- Metabolic syndrome in childhood : causes and effects / Weiss, R. -- Pathophysiology of insulin resistance in small for gestational age subjects : a role for adipose tissue? / Beltrand, J.; Meas, T.; Levy-Marchal, C. -- The neural feedback loop between the brain and adipose tissues / Pénicaud, L.
  • 2008 Springer Protocols
    Yang, Kaiping.
  • 2011 Springer Protocols
    Bunnell, Bruce A.; Gimble, Jeffrey M.
    Isolation and culture of rhesus adipose-derived stem cells -- Isolation of human adipose-derived stem cells from lipoaspirates -- Isolation of murine adipose-derived stem cells -- In vitro adult rat adipose tissue-derived stromal cell isolation and differentiation -- In vitro adult canine adipose tissue-derived stromal cell growth characteristics -- Adipogenic differentiation of adult equine mesenchymal stromal cells -- Isolation and culture of porcine adipose tissue-derived somatic stem cells -- Automated isolation and processing of adipose-derived stem and regenerative cells -- Methods for the purification and characterization of human adipose-derived stem cells -- Characterization of human adipose-derived stem cells using flow cytometry -- Evaluation of cellular and humoral immune responses to allogeneic adipose-derived stem/stromal cells -- Adipose-derived stromal cells: Cytokine expression and immune cell contaminants -- Gel-based and gel-free proteomic technologies -- Adipogenic differentiation of adipose-derived stem cells -- Three-dimensional culture systems to induce chondrogenesis of adipose-derived stem cells -- Neural differentiation of human adipose tissue-derived stem cells -- Osteogenic differentiation strategies for adipose-derived mesenchymal stem cells -- Generation of adipose stromal cell-derived hepatic cells -- Adipose stem cell differentiation into smooth muscle cells -- Endothelial and cardiac regeneration from adipose tissues -- Epithelial differentiation of human adipose-derived stem cells -- Screening for epigenetic target genes that enhance reprogramming using lentiviral-delivered shRNA -- Adipogenic differentiation of human adipose-derived stem cells on 3D silk scaffolds -- A first approach for the production of human adipose tissue-derived stromal cells for therapeutic use -- Viral transduction of adipose-derived stem cells -- Use of adipose-derived stem cells in high-throughput screening to identify modulators of lipogenesis -- Preservation protocols for human adipose tissue-derived adult stem cells -- Soft tissue reconstruction -- Methods for analyzing microRNA expression and function during osteogenic differentiation of human adipose tissue-derived mesenchymal stem cells -- The generation and the manipulation of human multipotent adipose-derived stem cells -- Cell sheet technology for tissue engineering: The self-assembly approach using adipose-derived stromal cells -- Differentiation of adipose-derived stem cells for tendon repair -- Adipose-derived stem cells for skin regeneration -- Adipose-derived stem cells for periodontal tissue regeneration.
  • 2009 Springer
    Castiglione, Monica; Piccart, Martine J.
    Also available: Print – 2009
  • 2011 ClinicalKey
    Adler, Francis Heed; Hoeve, James ver; Levin, Leonard A.; Nilsson, Siv F. E.; Wu, Samuel Miao-sin.
    Drs. Paul L. Kaufman, Albert Alm, Leonard A Levin, Siv F.E. Nilsson, James Ver Hoeve, and Samuel Wu present the 11th Edition of the classic text Adler's Physiology of the Eye, updated to enhance your understanding of ocular function. This full-color, user-friendly edition captures the latest molecular, genetic, and biochemical discoveries and offers you unparalleled knowledge and insight into the physiology of the eye and its structures. A new organization by function, rather than anatomy, helps you make a stronger connection between physiological principles and clinical practice; and more than 1,000 great new full-color illustrations help clarify complex concepts. You can also access the complete contents online at www.expertconsult.com. Deepen your grasp of the physiological principles that underlie visual acuity, color vision, ocular circulation, the extraocular muscle, and much more.
  • Tucker, David.
    AIR basics -- Application settings -- Application windows -- Screens -- HTML content -- PDF support -- Clipboard support -- Drag and drop support -- File system integration -- Embedded SQL database programming -- Encrypted local store -- Application and window native menus -- Taskbar and dock integration -- File types -- Service monitor framework -- Application updates -- AIR application distribution with the broswer API.
  • 2007 Springer
    Micheli, Lyle J.; Purcell, Laura Kathleen.
    Principles of rehabilitation / Michelina C. Cassella and Kathleen Richards -- Diagnostic Imaging / Vernon M. Chapman and Diego Jaramillo -- Traumatic head injuries / Laura Purcell -- Cervical and thoracic spine injuries / Pierre d' Hemecourt and Jessica Flynn Deede -- Lumbar spine injuries / Merrilee Zetaruk -- Thoracoabdominal injuries / Hamish Kerr, Christine Curtis, and Pierre d' Hemecourt -- Adolescent shoulder injuries / John A. Guido, Jr. and Treg Brown -- Elbow and forearm injuries / Anthony Luke, Margaret Lee, and Marc Safran -- Injuries to the wrist, hand, and fingers / Donald S. Bae -- Pelvic, hip, and thigh injuries / Jason H. Nielson -- Knee injuries / Michelle McTimoney -- Lower leg injuries / Angela D. Smith -- Foot and ankle injuries / Angus M. McBryde, Jr., Mark D. Locke, and John P. Batson.
  • 2010 Springer
    Dauchy, Sarah; Godet, Jacqueline; Razavi, Darius.
  • 2008 Ovid
    Neinstein, Lawrence S.
  • Google Books
    Also available: Print – 1991-
  • Google Books
    Also available: Print – 1991-
  • 2014 Springer
    Foelsch, Pamela A.; Schlüter-Müller, Susanne; Schmeck, Klaus.
    1. Introduction -- 2. Description of the Disorder -- 3. Theoretical Models and Rationale -- 4. Diagnosis and Treatment Indications -- 5. Treatment -- 6. Adolescent Identity Treatment (AIT) Case Illustration -- 7. Efficacy -- 8. Training and Supervision.
  • 2011 ClinicalKey
    Slap, Gail B.
    This concise, evidence-based resource covers all of today₂s need-to-know information to quickly and effectively diagnose and manage common adolescent conditions ... in an exceptionally user-friendly format. Because it's so compact, clinically oriented, and easy to read, Adolescent Medicine: The Requisites in Pediatrics is an ideal study tool as well as a convenient reference for practice. Includes detailed discussions on special health issues, common medical problems, sexual and reproductive health, behavioral problems, and the transition to adult health care to help you gain a better understanding of the unique needs of the adolescent patient. Features a logical, consistent chapter format that helps you find the guidance you need quickly. Presents abundant tables, differential diagnoses, lab values/radiologic studies, treatment/therapy recommendations, and guidance on when to refer to a specialist equipping you for every clinical challenge. Discusses controversies concerning the standard of care with the aid of thought-provoking clinical scenarios to help you to determine the best course of action in difficult situations. Provides highlighted boxes that emphasize relevant case studies, key points of each section, and other important information making you aware of considerations that impact today's practice. Uses a wealth of illustrations so you can see details more clearly.
  • 2009 Springer
    Gullotta, Thomas; Leukefeld, Carl G.; Staton-Tindall, Michele.
    1 A Selected Social History of the Stepping-Stone Drugs / Thomas P. Gullotta 1 -- 2 A Biological/Genetic Perspective: The Addicted Brain / Thomas H. Kelly, Alessandra N. Kazura, Karen M. Lommel, Shanna Babalonis, Catherine A. Martin 15 -- 3 Individual Characteristics and Needs Associated with Substance Misuse of Adolescents and Young Adults in Addiction Treatment / Michael L. Dennis, Michelle K. White, Melissa L. Ives 45 -- 4 Adolescent Substance Abuse Treatment: A Review of Evidence-Based Research / Ken C. Winters, Andria M. Botzet, Tamara Fahnhorst, Randy Stinchfield, Rachel Koskey 73 -- 5 Adolescent Outpatient Treatment / Richard Dembo, Randolph D. Muck 97 -- 6 Evidence-Based Family Treatment of Adolescent Substance Abuse and Dependence / Shaun I. Calix, Mark A. Fine 119 -- 7 Residential Treatment of Adolescents with Substance Use Disorders: Evidence-Based Approaches and Best Practice Recommendations / Robert W. Plant, Peter Panzarella 135 -- 8 Primary Prevention in Adolescent Substance Abuse / Martin Bloom, Thomas P. Gullotta 155 -- 9 Religious Involvement and Adolescent Substance Use / Terrence D. Hill, Amy M. Burdette, Michael L. Weiss, Dale D. Chitwood 171 -- 10 School Prevention / Zili Sloboda 191 -- 11 Community Prevention Handbook on Adolescent Substance Abuse Prevention and Treatment: Evidence-Based Practices / Elizabeth J. D'Amico, Matthew Chinman, Stefanie A. Stern, Abraham Wandersman 213 -- Epilogue: The Status of Knowledge Development and the Unknown / Michele Staton-Tindall, Thomas P. Gullotta, William Walton Stoops, Carl G. Leukefeld 251.
  • 2015 Wiley
    Woodhouse, C. R. J.
    Adolescent and transitional urology : an introduction -- Anatomical and cystic anomalies -- Stones -- Prune-belly syndrome -- Renal function in adolescents -- Structural anomalies and reconstruction of the ureter -- Vesico-ureteric reflux -- The neuropathic bladder and spina bifida -- Lower urinary tract replacement and reconstruction -- Urinary diversion and undiversion -- Other bladder conditions -- Exstrophy and epispadias -- Cloacal exstrophy -- Posterior urethral valves -- Hypospadias -- Scrotal abnormalities -- The overvirilized female -- The undervirilized male -- Adolescent sexuality and counseling -- Neoplastic disease : outcomes in survivors.
  • 2014
    Colbert, James; Kocot, S. Lawrence; McClellan, Mark B.; Monterastelli, Mark; Mostashari, Farzad; Seidman, Joshua; White, Ross.
    Part 1. Introduction-- Physician Practices and Their Critical Role in the Accountable Care Movement -- 1. Identifying and Managing High-Risk Patients -- 2. Developing High Value Referral Networks -- 3. Using Event Notifications -- 4. Engaging Patients -- Part 2. Case Studies in Accountable Care -- Case Studies in Accountable Care -- Appendix A. Sample ACO Annual Operating Budget -- Appendix B. Helpful Links and Resources -- Appendix C. Glossary of Key Terms.
  • 2013 Karger
    Kellum, John A.; McCullough, Peter A.; Mehta, Ravindra L.; Murray, Patrick T.; Ronco, C.
    Acute Dialysis Quality Initiative (ADQI) / Ronco, C., Kellum, J., Bellomo, R., Mehta, R. -- Implementation of novel biomarkers in the diagnosis, prognosis, and management of acute kidney injury : executive summary from the tenth consensus conference of the Acute Dialysis Quality Initiative (ADQI) / McCullough, P.A., for the Acute Dialysis Quality Initiative (ADQI) Consensus Group -- Diagnosis of acute kidney injury using functional and injury biomarkers : workgroup statements from the tenth Acute Dialysis Quality Initiative Consensus Conference / McCullough, P.A., for the ADQI 10 Workgroup -- Differential diagnosis of AKI in clinical practice by functional and damage biomarkers : workgroup statements from the tenth Acute Dialysis Quality Initiative Consensus Conference / Endre, Z.H., for the ADQI 10 Workgroup -- Use of biomarkers to assess prognosis and guide management of patients with acute kidney injury / Cruz, D.N., for the ADQI 10 Workgroup -- Physiological biomarkers of acute kidney injury : a conceptual approach to improving outcomes / Okusa, M.D., for the ADQI 10 Workgroup -- Pathophysiology of the cardiorenal syndromes : executive summary from the eleventh onsensus conference of the Acute Dialysis Quality Initiative (ADQI) / McCullough, P.A., for the Acute Dialysis Quality Initiative (ADQI) Consensus Group. Pathogenesis of cardiorenal syndrome type 1 in acute decompensated heart failure : workgroup statements from the eleventh consensus conference of the Acute Dialysis Quality Initiative (ADQI) / Haase, M., for the Acute Dialysis Quality Initiative (ADQI) Consensus Group -- Pathophysiology of cardiorenal syndrome type 2 in stable chronic heart failure : workgroup statements from the eleventh consensus conference of the Acute Dialysis Quality Initiative (ADQI) / Cruz, D.N., ; for the Acute Dialysis Quality Initiative (ADQI) Consensus Group -- Cardiorenal syndrome type 3 : pathophysiologic and epidemiologic considerations / Bagshaw, S.M., for the Acute Dialysis Quality Initiative 11 Working Group -- Cardiorenal syndrome type 4 : insights on clinical presentation and pathophysiology from the eleventh consensus conference of the Acute Dialysis Quality Initiative (ADQI) / Tumlin, J.A., for the Acute Dialysis Quality Initiative (ADQI) 11 Consensus Group -- Cardiorenal syndrome type 5 : clinical presentation, pathophysiology, and management strategies from the eleventh consensus conference of the Acute Dialysis Quality Initiative (ADQI) / Mehta, R.L., for the Acute Dialysis Quality Initiative (ADQI) 11 Working Group.
  • 2009 Springer
    Blake, Michael A.; Boland, Giles W. L.
    Adrenal embryology and pathology -- Adrenocortical dysfunction -- Adrenal medullary dysfunction -- Adrenals in oncology -- Adrenal surgery -- Imaging adrenal dysfunction -- Imaging of pheochromocytomas -- Adrenal imaging using computed tomography: differentiation of adenomas and metastasis -- MRI of the adrenal glands -- Single photon imaging of the adrenal gland -- PET and PET-CT imaging of adrenal lesions -- Adrenal trauma and intervention -- Evolving functional and advanced image analysis techniques for adrenal lesion characterization.
  • 1980-
    Andén, N.-E; Szekeres, L.
  • 2006 Springer
    Perez, Dianne M.
  • 2011 Springer
    Else, Tobias; Hammer, Gary D.
    "This first edition of the textbook “Adrenocortical Carcinoma: Basic Sciences and Clinical Concepts” provides a concise compilation of relevant data advancing our current understanding of this rare cancer. Chapters are dedicated to various aspects of both the basic biology and the clinical science relating to adrenocortical carcinoma (ACC). Expert clinicians introduce the reader to current state-of-the-art clinical care of patients with ACC. As a considerable body of knowledge on ACC has accumulated over the last decades, expert scientists have authored additional sections that serve as a reference source for the experienced researcher as well as an introduction for the trainee in the laboratory or clinic. Clinical topics span the epidemiology, diagnosis and therapy of ACC. Scientific topics areas span the pathology and pathophysiology of ACC with a special focus on experimental models of adrenocortical tumors and recent advances in the genetic aspects and signaling pathways in ACC. The content of this book was compiled and edited with the intent of facilitating the translation of knowledge into future diagnostic and therapeutic tools that will ultimately improve patient care."--Publisher's website.
  • 2006 CRCnetBASE
    Quirke, N.
  • 2011 Springer
    Advani, Anjali S.; Lazarus, Hillard M.
    A perspective on the treatment of acute lymphoblastic leukemia in adults -- Acute lymphocytic leukemia: clinical features and making the diagnosis -- The biology of adult acute lymphoblastic leukemia -- Minimal residual disease in acute lymphoblastic leukemia -- Cytogenetics -- Acute lymphoblastic leukemia: epidemiology -- Prognostic factors in adult acute lymphoblastic leukemia (ALL) -- The generalized care of the patient with acute lymphoblastic leukemia -- Treatment of acute lymphoblastic leukemia in middle-age and older adults -- Pharmacology of acute lymphoblastic leukemia therapy -- Assessment of response to treatment -- T-cell acute lymphoblastic leukemia -- Burkitt lymphoma and leukemia -- Treatment of acute lymphoblastic leukemia in young adults -- Philadelphia chromosome positive acute lymphoblastic leukemia -- Molecular therapies -- Treatment of relapsed acute lymphoblastic leukemia -- Allogeneic stem cell transplantation for acute lymphoblastic leukemia in adults -- Hematopoietic stem cell transplantation in Philadelphia-positive acute lymphoblastic leukemia -- Special challenges: genetic polymorphisms and therapy -- Late consequences of therapy of acute lymphoblastic leukemia -- Immunotherapy for acute lymphoblastic leukemia -- Unique subtypes in acute lymphoblastic leukemia.
  • 2013 Springer
    Kooij, J. J. Sandra.
    1. Introduction -- 2. Diagnostic assessment -- 3. Diagnostic instruments -- 4. Treatment -- 5. Treatment: coaching adults with ADHD -- 6. Setup and organization of a specialist department.
  • 2012 Springer
    Turksen, Kursad.
  • 2004 Ovid
    An, Howard S.; Frymoyer, John W.; Wiesel, Sam W.
    Also available: Print – v. 1-2, 2004.
  • 2002 Ovid
    Gillenwater, Jay Y.
    Also available: Print – v. 1-3, 2002.
  • 2015 AccessSurgery
    Bueno, Raphael; Colson, Yolonda L.; Jaklitsch, Michael T.; Krasna, Mark; Mentzer, Steven J.; Sugarbaker, David J.
  • 2009 AccessSurgery
    Sugarbaker, David J.
    Care and management of the thoracic surgery patient -- Esophageal and proximal stomach malignancy -- Esophageal motility disorders -- Esophageal reflux disorders -- Benign congenital and traumatic esophageal disorders -- Benign disorders of the upper airways -- Cancer of the upper airways -- Lung cancer -- Benign tumors and conditions of the lung -- Chronic obstructive pulmonary disease -- Lung infections and interstitial lung disease -- Lung transplantation -- Diffuse pleural malignancies and effusions -- Benign pleural conditions -- Chest wall and sternal tumors -- Benign disorders of the chest wall -- Diaphragmatic diseases, benign or malignant -- Mediastinal diseases, benign or malignant -- Robotics.
  • 2007 Ovid
    Callaghan, John J.; Rosenberg, Aaron G.; Rubash, Harry E.
    Also available: Print – v. 1-2., 2007
  • 2014
    Rigamonti, Daniele.
  • CDC
  • CDC
  • 1982-
    Bloomfield, Clara D.
    Status: Not Checked OutLane Catalog Record
  • NGC
  • 2012 Wiley
    Melsen, Birte.
    Who are the patients -- Chief complaints and problem -- Etiology -- Primary or secondary malocclusions -- Collaboration- Multidisciplinary -- Interdisciplinary -- Treatment planning -- Definition of treatment goal -- Tissue reaction -- Appliance design -- Bonding problem related to adult reconstructed dentitions -- Material related side effects in orthodontics -- Treatment sequence -- Anchorage problems -- Lingual orthdontics -- Patients with periodontal problems -- Patients with prosthodontic problems -- Patients with TMJ problems -- Surgical solution -- Where is the limit? -- Maintenance.
  • 2007 Ovid
    Berry, Daniel J.; Steinmann, S.
    Also available: Print – 2007
  • 2007 ClinicalKey
    Beredjiklian, Pedro K.; Garino, Jonathan P.
    Total hip arthroplasty / Sharat K. Kusuma and Jonathan P. Garino -- Total knee arthroplasty / Javad Parvisi, Peter Sharkey, and James A. Sanfilippo -- Ankle arthroplasty / Sudheer Reddy, David I. Pedowitz, and Enyi Okereke -- Shoulder arthroplasty / Joseph A. Abboud, Charles L. Getz, and Gerald R. Williams, Jr. -- Elbow arthroplasty / Bradford Parsons, Sudheer Reddy, and Matthew L. Ramsey -- Total joint replacement. Effects of materials and designs on osteolysis / Ian C. Clarke, Thomas Donaldson, and Christopher Jobe ; Greater expectations and greater loads : implications for biomechanics / Edward Ebramzadeh, Sophia N. Sangiorgio, and Ian C. Clarke -- Joint kinematics and biomechanics of the hip and knee / Craig L. Israelite ... [et al.] -- Joint biology / David Glaser -- Biology of bone graft / Gregory F. Carolan, Kingsley R. Chin, and Matthew Werger -- Joint anatomy / Mark I. Froimson, Robert Molloy, and Steve Maschke -- Arthritis / Neil P. Sheth and Charles L. Nelson -- Preoperative assessment / William G. Hamilton and Ehsan Tabaraee -- Total wrist arthroplasty / David J. Bozentka and Robert B. Carrigan -- Arthroplasty in the joints of the hand / Pedro K. Beredjiklian, Virak Tan, and Sanjiv Naidu -- Limb salvage techniques in lower extremity segmental bone defects / Harish S. Hosalkar, Kristofer J. Jones, and Richard D. Lackman -- Outcomes assessment / Norman A. Johanson and Douglas L. Cerynik -- Particle disease and implant allergy / Nadim J. Hallab and Joshua J. Jacobs.
    Also available: Print – 2007
  • 2006 ScienceDirect
    Klimanskaya, Irina; Lanza, R. P.
    Ectoderm -- Mesoderm -- Endoderm -- Extraembryonic and perinatal stem cells.
    Also available: Print – 2006
  • 2011 Springer
    Phinney, Donald G.
    Basic Biology of Adult Stem Cells -- Molecular Mechanisms Regulating Adult Stem Cell Self-Renewal -- Maintenance of Adult Stem Cells: Role of the Stem Cell Niche -- The Emerging Role of microRNAs in Adult Stem Cells -- Expression and Function of Pluripotency Genes in Adult Stem Cells -- Adult Stem Cell Plasticity Revisited --Characterization of Adult Stem Cells -- Lineage Tracing of Tissue-Specific Stem Cells In Vivo -- Surrogate Measures of Adult Stem Cell Self-Renewal: The Neural Stem Cell Paradigm -- ABC Transporters, Aldehyde Dehydrogenase, and Adult Stem Cells -- Regulation of Life Span and Immortalization -- Regulation of Life Span in Adult Stem Cells -- The Cancer Stem Cell Paradigm.
  • 2015 Karger
    Rudolph, K. Lenhard.
    Speakers at the symposium -- Stem cells in adult intestine / Feng, J., Sperka, T. -- Molecular mechanisms of muscle stem cell aging / Schwërer, S., Tümpel, S. -- Mechanism of functional alterations in hematopoietic stem cell aging / Morita, Y. -- The microenvironment, aging, and disease / Geiger, H. -- Sestrins in aging and metabolism / Tang, D., Tao S. -- Telomeres and stem cell aging / Felix, D.A. -- DNA damage and checkpoint responses in adult stem cells / Romanov, V., Shukla, A., Ju, Z.
  • 2014 Springer
    Biller-Andorno, Nikola; Brauer, Susanne; Lack, Peter.
    This volume gives an overview on the currently debated ethical issues regarding advance directives from an international perspective. It focuses on a wider understanding of the known and widely accepted concept of patient self-determination for future situations. Although advance directives have been widely discussed since the 1980s, the ethical bases of advance directives still remain a matter of heated debates. The book aims to contribute to these controversial debates by integrating fundamental ethical issues on advance directives with practical matters of their implementation. Cultural, national and professional differences in how advance directives are understood by health care professions and by patients, as well as in laws and regulations, are pinpointed.
  • 2015 Springer
    Wei, Dongqing.
    This text examines in detail mathematical and physical modeling, computational methods and systems for obtaining and analyzing biological structures, using pioneering research cases as examples. As such, it emphasizes programming and problem-solving skills. It provides information on structure bioinformatics at various levels, with individual chapters covering introductory to advanced aspects, from fundamental methods and guidelines on acquiring and analyzing genomics and proteomics sequences, the structures of protein, DNA and RNA, to the basics of physical simulations and methods for conformation searches. This book will be of immense value to researchers and students in the fields of bioinformatics, computational biology and chemistry. Dr. Dongqing Wei is a Professor at the Department of Bioinformatics and Biostatistics, College of Life Science and Biotechnology, Shanghai Jiaotong University, Shanghai, China. His research interest is in the general area of structural bioinformatics.
    Also available: Print – 2015
  • 2012 ClinicalKey
    Gillam, Linda D.; Otto, Catherine M.
    Transthoracic three dimensional echocardiography / Victor Mor-Avi, Roberto Lang -- Advanced echocardiography approaches: 3D transesophageal assessment of the mitral valve / Jonathan Passeri, Judy Hung -- Two -dimensional and three dimensional echocardiographic evaluation of the right ventricle / Takahiro Shiota -- Transthoracic and transesophageal echocardiography in the catheterization laboratory / Rebecca Hahn and Linda Gillam -- Intracardiac echocardiography for common interventions on structural heart disease / Anna Bortnick and Frank Silvestry -- Strain and strain-rate imaging / Thomas Marwick -- Assessing twist and torsion / Sherif Nagueh -- Echocardiographic tools for cardiac resynchronization therapy / Veronica Lea Dimaano, Kristian Eskesen, and Theadore Abraham -- Contrast perfusion echocardiography / Joan Olson, Feng Xie, and Thomas Porter -- Evaluation of coronary blood flow by echo doppler / Nozomi Watanabe -- Stress testing for structural heart disease / Catherine Otto and David Owens -- Multimodality cardiac imaging -- when is echo not enough? / Nuno Cortez Dias, Ana Almeida, and Fausto Pinto.
  • 2007 ScienceDirect
    Hughes, Kelly Thomas; Maloy, Stanley R.
    Strain collections and genetic nomenclature / S.R. Maloy ... [et al.] -- Use of antibiotic-resistant transposons for mutagenesis / S.R. Maloy -- In vivo mutagenesis using EZ-Tn5 / J.R. Kirby -- Identification of essential genes in bacteria / D.R. Hillyard ... [et al.] -- Isolation of transposon insertions / S.R. Maloy -- Localized mutagenesis / S.R. Maloy -- Generation of deletions and duplications using transposons as portable regions of homology with emphasis on Mud and Tn10 transposons / K.T. Hughes -- Target-directed proteolysis in vivo / M. Eser ... [et al.] -- Sets of transposon-generated sequence-tagged mutants for structure-function analysis and engineering / B. Traxler ... [et al.] -- Using genomic microarrays to study insertional/transposon mutant libraries / D.N. Baldwin ... [et al.] -- Screening transposon mutant libraries using full-genome oligonucleotide microarrays / K. M. Winterberg ... [et al.] -- Creating recombination-activated genes and sequence-defined mutant libraries using transposons / L. Gallagher ... [et al.] -- Use of operon and gene fusions to study gene regulation in Salmonella / K.T. Hughes ... [et al.] -- Genomic screening for regulatory genes using the T-POP transposon / C. Lee ... [et al.] -- Recombineering: In vivo genetic engineering in E. coli, S. enterica, and beyond / J.A. Sawitzke ... [et al.] -- [lambda]-red genetic engineering in Salmonella enterica serovar Typhimurium / J.E. Karlinsey -- Probing nucleoid structure in bacteria using phage lambda integrase-mediated chromosome rearrangements / N. Garcia-Russell ... [et al.] -- Dissecting nucleic acid-protein interactions using challenge phage / S.R. Maloy ... [et al.] -- Mud-P22 / J.A. Crain ... [et al.] -- Phage metagenomics / V. Casas ... [et al.].
    Also available: Print – 2007
  • 2012 CRCnetBASE
    Broemeling, Lyle D.
    1. Introduction -- 2. Medical tests and preliminary information -- 3. Preview of the book -- 4. Fundamentals of diagnostic accuracy -- 5. Regression and medical test accuracy -- 6. Agreement and test accuracy -- 7. Estimating test accuracy with an imperfect reference standard -- 8. Verification bias and test accuracy -- 9. Test accuracy and medical practice -- 10. Accuracy of combined tests -- 11. Bayesian methods of meta-analysis.
  • 2013 Springer
    Mizin, Volodymyr I.; Omelchenko, Alexander; Pierce, Grant N.
    "The probability for exposure to damaging radiation, toxic chemicals in the environment and adverse biological agents has increased exponentially today. The more frequent and faster travel that we experience today also escalates the risk of contraction and transmission of potentially deadly infections. This has created a very real and escalating risk for injuries and deaths. This is accentuated in the military and medical staff that is more frequently exposed to radiological, chemical, and biological agents in their normal working environment. Understanding the mechanisms whereby these toxic agents inflict damage to our bodies is essential to prepare us for these challenges. Much of the damage is inflicted through the generation of free radicals and non-radical oxidants which then act through oxidative mechanisms to injury the body. This volume will discuss the damage caused by these radiological, chemical, and biological environmental stressors, the mechanisms through which the damage can occur and the novel strategies that can be used to reduce the injury inflicted by these toxic compounds. Using basic and clinical research approaches, the contents of this book discuss new ideas for the development of bioactive products and environmental approaches to lessen or negate the biological damage inflicted by these noxious compounds."--Publisher's website.
  • 2007 Springer
    Qin, L.
  • 2014 Wiley
    Nordin, Anis N.; Tiwari, Ashutosh.
    1. Frotiers for bulk nanostructured metals in biomedical applications -- 2. Stimuli-responsive materials used as medical devices in loading and releasing of drugs -- 3. Recent advances with liposomes as drug carriers -- 4. Fabrication, properties of nanoshells with controllable surface charge and its applications -- 5. Chitosan as an advanced healthcare material -- 6. Chitosan and low molecular weight chitosan: biological and biomedical applications -- 7. Anticipating behaviour of advanced materials in healthcare -- 8. Label-free biochips -- 9. Polymer MEMS sensors -- 10. Assembly of polymers/metal nanoparticles and their applications as medical devices -- 11. Combination of molecular imprinting and nanotechnology: beginning of a new horizon -- 12. Prussian blue and analogues: biosensing applications in health care -- 13. Efficiency of biosensors as new generation of analytical approaches at the biochemical diagnostics of diseases -- 14. Nanoparticles: scope in drug delivery -- 14. Smart polypeptide nanocarriers for malignancy therapeutics -- Index.
  • 2015 ScienceDirect
    Gaemperli, Oliver; Lancellotti, Patrizio; Nieman, Koen; Plein, Sven.
    "Advances in Cardiac Imaging presents the latest information on heart disease and heart failure, major causes of death among western populations. In addition, the text explores the financial burden to public healthcare trusts and the vast amount of research and funding being channeled into programs not only to prevent such diseases, but also to diagnose them in early stages. This book provides readers with a thorough overview of many advances in cardiac imaging. Chapters include technological developments in cardiac imaging and imaging applications in a clinical setting with regard to detecting various types of heart disease"--Provided by publisher.
  • 2011
    Navarro, Kenneth; Sinz, Elizabeth.
    Status: Not Checked OutLane Catalog Record
    Course overview -- The systematic approach: the BLS and ACLS surveys -- Effective resuscitation: team dynamics -- Systems of care -- The ACLS cases.
  • 2014 Springer
    Sonoda, Toyooki.
    Endoscopic Instruments -- Difficult Polpys: Conventional methods -- Endoscopic Mucosal Resection (EMR) -- Endoscopic Submucosal Dissection (ESD) -- Combined Endoscopic and Laparoscopic Surgery (CELS) -- Colonic Stenting -- Endoscopic Treatment of Perforations of Fistulas.
  • v. 10, 2005. Springer
    Geddes, Chris D.; Lakowicz, Joseph R.
    pt. A. Small molecule sensing -- pt. B. Macromolecular sensing.
  • 2012 Thieme Book
    Alt, Volker; Bhandari, Mohit; Robioneck, Bernd; Schemitsch, Emil H.; Sprague, Sheila.
    1. Factorial Randomized Trials -- Summary -- Introduction -- Randomized clinical trial design strategies with multiple interventions -- Selecting a factorial randomized design -- Conclusion -- 2. Expertise-based randomized trials -- Summary -- Introduction -- Conventional RCT design -- Expertise-based RCT design -- Challenges of expertise-based RCTs -- Independent assessor -- Balanced and consecutive or random contributions to screening pool -- Perceived equivalence between practices -- Conclusion -- 3. Randomization systems and technology -- Summary -- Introduction -- Methods of patient allocation -- Other considerations -- Conclusion -- 4. Blinding and concealment -- Summary -- Introduction -- Concealment -- Blinding -- Conclusion -- 5. Composite outcome in orthopaedics: understanding the concepts -- Summary -- Introduction -- Rationale for use of a composite outcome -- Limitations of using composite outcomes -- Guidelines for creating a "good" composite outcome -- Reporting and interpreting composite outcomes -- Conclusion -- 6. Adjudication of outcomes-systems and approaches -- Summary -- Introduction -- Importance of adjudication -- Process of adjudication -- Existing methods of adjudication -- Web-based adjudication -- Conclusion -- 7. Subgroup analyses -- Summary -- Introduction -- Subgroup analysis defined -- Design of a subgroup analysis -- Reporting -- Interpretation -- Conclusion -- 8. Trial management-advance concepts and systems -- Summary -- Introduction -- Phases of clinical trials -- Common considerations in conducting a clinical trial -- Trial committees -- The search for funding -- Conclusion 9. Case-control studies -- Summary -- Introduction -- Definition of a case-control study -- Conclusion -- 10. Cohort studies -- Summary -- Introduction -- Cohort studies in the hierarchy of evidence -- Types of cohort study designs -- Methods for reducing confounding and assessing causality -- A checklist to evaluate or improve the strength of evidence -- Conclusion --; 11. Survey Design -- Summary -- Introduction -- Identifying a research question -- Survey development -- Survey design -- Using exiting surveys -- survey validataion -- Pilot testing -- Survey administration -- Ethical considerations -- Financial considerations -- Conclusion -- 12. Qualitative studies -- Summary -- Introduction -- What is qualitative research? -- How is qualitative research done? -- Conclusion -- 13. Economic analysis -- Summary -- Introduction -- Theoretical background -- Conducting health economics studies -- Conclusion -- 14. Literature searches -- Summary -- Introduction -- When to conduct a literature search -- How to conduct a literature search -- Study selection -- Assessing methodological quality of studies -- Data extraction and analysis -- Conclusion -- 15. Summary -- Introduction -- the P value does not assess the magnitude of a treatment effect -- The challenge of comparing results across studies -- Types of effect sizes -- Confidence intervals for effect sizes -- Use of effect size in meta-analysis -- Conclusion -- 16. Fixed effects versus random effects -- Summary -- Introduction -- the data pool: fixed effects versus random effects -- Deciding which model to use -- Conclusion -- 17. Heterogeneity -- Summary -- Introduction -- Heterogeneity defined -- Identifying heterogeneity -- Dealing with heterogeneity -- Conclusion -- 18. Uncovering publicatiion bias -- Summary -- Introduction -- Authors and publication bias -- Detecting and adjusting for publication bias -- Minimizing the effect of publication bias -- A possible solution: trial registers -- Conclusion -- 19. Statiecal pooling - programs and systems -- Summary -- Introduction -- Selectin the appropriate programs and systems: factors to consider --Review of programs and systems -- Types of programs and systems -- Recommendations -- Conclusion -- 20. Meta-analysis of observational studies -- Summary -- Introduction -- The observational data dilemma -- Conclusion -- 21. Meta-regression -- Summary -- Introduction -- Heterogeneity and meta-regression -- Meta-regression mechanics -- Interpreting a meta-regression -- Limitations of meta-regression -- Conclusion -- 22. Preparing a statistical analysis plan -- Summary -- Introduction -- Data management -- Statistical procedures -- Data safety and monitoring board -- Sample size -- Interim analysis -- Reports to investigators -- Sensitivity analysis -- Tables of presentation and publication -- Software -- Reporting guidelines -- General policies -- Privacy considerations -- Apendices -- What is in the literature about SAP? -- Conclusion --; 24. Survival analysis -- Summary -- Introduction -- Documenting time-to-event (survival) data -- the rationale for time-to-event (survival) analysis -- Methods for survival analysis -- Comparing groups -- Practical considerations in the desin of time-to-event studies -- Conclusion -- 25. Interim analyses in randomized trials -- Summary -- Introduction -- Interim analysis defined -- Design of an interim analysis -- Data monitoring committees -- Consequences of stopping early for benefit -- Conclusion -- 26. Conflicts of interest reporting -- Summary -- Introduction -- Legal implications -- Types of conflict of interest -- Who should disclose conflicts of interest? -- When must conflicts of interest be disclosed? -- Guidelines and recommendations for disclosure -- Why must personal financial interests be disclosed? -- Alternatives to disclosure policies -- Conclusion -- 27. Authorship-modern approaches and reporting -- Summary -- Introduction -- Academic stream -- Educational stream -- Industrial stream -- Popular media stream -- Conclusion -- 28. Randomized trials reporting checklists -- Summary -- Introduction -- Consort statement -- Nonpharmacological trials -- NPT extension to consort statement -- CLEAR NPT -- Conclusion -- 29. Observational studies reporting checklists -- Summary -- Introduction -- Checklist for observational studies: the STROBE statement -- Guide to investigators: how to used the STROBE statement -- The STROBE statement: explanations of checklist items -- Conclusion -- 30. Meta-analysis reporting checklists -- Summary -- Introduction -- Meta-analysis reporting checklists -- Conclusion -- Resources and contacts for surgical research -- Summary -- Introduction -- Mentorship -- Graduate programes -- Online courses -- Textbooks and journals -- Courses and workshops -- Contract research organizations -- Conclusion -- Glossary of terms.
  • 2013 Springer
    Shiffman, Melvin A.
    In this book, international experts present up-to-date techniques of otoplasty in which they have extensive personal experience. Both new and modified procedures are described with the aid of a wealth of high-quality illustrations. In addition to these detailed descriptions, ear embryology and anatomy, psychological issues, postoperative care, possible risks and complications, and outcomes are extensively covered in order to provide the reader with a state of the art account of all aspects of cosmetic otoplasty.
  • 2006
    Phibbs, Brendan.
    Status: Not Checked OutLane Catalog Record
  • 2010 CRCnetBASE
    Markov, Marko; Miklavčič, Damijan; Pakhomov, Andrei G.
    "A reflection of the intense study of the effects of electromagnetic fields on living tissues that has taken place during the last several decades, this book discusses the theoretical and experimental evidence and considerations the effects of strong electromagnetic fields and/or electric pulses and their importance in medicine and biology. The authors present the basic techniques applied in electroporation and the advanced methods for creation of nanopores, highlighting their basic science and clinical applications. Topics include nano electroporation, classic electroporation, experimental evidence for electroporation of living cells, and electroporation for cancer and wound healing"--Provided by publisher.
  • 2006 Springer
    Nakada, Stephen Y.; Pearle, Margaret Sue.
  • 2013
    Borer, Katarina T.
    Unique properties of endocrine and autonomic messengers -- Activation of non-hormonal signaling during exercise -- Autonomic and hormonal control of the cardiorespiratory system -- Body fluid balance -- Hormones and fuel use in exercise -- Hormonal control of energy expenditure and intake -- Exercise and reproductive hormones -- Hormonal mediation in training adaptations -- Exercise and endocrine rhythms.
  • 2015 Springer Protocols
    Verveer, Peter J.
    The physical basis of total internal reflection fluorescence (TIRF) microscopy and its cellular applications -- Two-photon excitation microscopy and its applications in neuroscience -- Live spheroid formation recorded with light sheet-based fluorescence microscopy -- Fluorescence microscopy-based RNA interference screening -- Fluorescence resonance energy transfer microscopy (FRET) -- Localizing protein-protein interactions in living cells using fluorescence lifetime imaging microscopy -- Analysis of biomolecular dynamics by FRAP and computer simulation -- Fluorescence correlation spectroscopy -- Homo-FRET imaging highlights the nanoscale organization of cell surface molecules -- Practical structured illumination microscopy -- 4Pi microscopy of the nuclear pore complex -- Application of STED microscopy to cell biology questions -- Three-dimensional photoactivated localization microscopy with genetically expressed probes -- Direct stochastic optical reconstruction microscopy (dSTORM) -- Optogenetics: Optical control of a photoactivatable Rac in living cells.
  • 2015 Springer
    Robbins, Lawrence D.
    Chapter 1. Migraine and Headache: General -- Chapter 2. Refractory(Difficult to Treat) Headache -- Chapter 3. Child and Adolescent Headaches -- Chapter 4. Cluster Headache. Chapter 5. Psychological Comorbidities -- Chapter 6. Case Studies -- Chapter 7. Miscellaneous.
  • 2014 Wiley
    Tiwari, Ashutosh.
    "Advanced Healthcare Nanomaterials summarises the current status of knowledge in the fields of advanced materials for functional therapeutics, point-of-care diagnostics, translational materials, up and coming bio-engineering devices"-- Provided by publisher.
  • 2006 Springer
    Skucas, Jovitas.
  • 2010 Springer
    Koizumi, Misako; Watanabe, Hideomi.
  • 2010 Springer
    Katkhouda, Namir.
    General concepts -- Cholecystectomy -- Common bile duct explorations and bilioenteric anastomosis -- Laparoscopic liver surgery -- Esophageal surgery -- Gastric surgery -- Appendectomy -- Colorectal procedures -- Small bowel obstruction -- Inguinal hernia repair -- Incisional and ventral hernia repair including component separation -- Splenectomy (total and partial) and splenopancreatectomy -- Adrenalectomy -- Bariatric surgery -- Single-access laparoscopic surgery (SALS) -- Advanced laparoscopic suturing techniques.
  • 2014 Springer
    Brandes, Steven B.; Morey, Allen F.
    Since the publication of the first edition of Urethral Reconstructive Surgery, important refinements have been added to the urologic surgical armamentarium. Extensively revised and updated, Advanced Male Urethral and Genital Reconstructive Surgery, Second Edition guides urologists in a practical manner on how to evaluate and manage complex urethral and male genital reconstructive challenges. Chapters have been added on wound healing, synchronous urethral strictures, non-transecting anastomotic urethroplasty (including muscle and vessel sparing), overlapping buccal grafts, male urethral slings, genital skin grafting, Peyronies surgery, priapism, pediatric strictures, and prosthetics. Such chapters greatly strengthen the overall appeal of the book. The volume closes with a new comprehensive appendix of preferred instruments. With broad contributions by international authorities in reconstructiveurologic surgery, Advanced Male Urethral and Genital Reconstructive Surgery, Second Edition is a valuable resource for all urologists, from residents to reconstructive surgeons.
  • 2007 ProQuest Safari
    Krieger, Stephanie.
  • 2014 Wiley
    Lomer, Miranda.
    Physiology and function of the gastrointestinal and hepatobiliary tract -- Dietary components relevant to gastrointestinal health -- Gastrointestinal disorders -- Hepatobiliary disorders.
  • 2011 ScienceDirect
    Bartlett, David W.; Ricketts, David.
    Management of dental caries / David Ricketts, Graham Chadwick and Andrew Hall -- Periodontal disease / Angela Gilbert -- Endodontic problems in advanced operative dentistry / William Saunders -- Tooth wear / David Bartlett -- Aesthetic problems / David Bartlett -- Occlusion / David Ricketts -- Cores / Carol Tait and David Rickett -- Gold crowns / John Radford, Brian Stevenson -- Gold restorations / Graham Chadwick, John Radford and David Ricketts -- Metal ceramic crowns / Brian Stevenson -- All ceramic crowns / Andrew Hal and Graham Chadwick -- Inlays, onlays, and veneers / David Bartlett and David Ricketts -- Impression materials and techniques / David Ricketts -- Provisional restorations / John Radford and David Ricketts -- Getting the appearance correct / Brian Stevenson -- Complex multiple fixed and combined fixed and removable prosthodontics / David Bartlett and David Ricketts -- When and how to replace missing teeth / David Ricketts -- Minimal preparation (resin retained) bridges / David Ricketts -- Conventional bridges / David Bartlett and David Ricketts.
  • pt. A-B, 2007. Springer
    pt. B, 2007 Springer
    Carey, Francis A.; Sundberg, Richard J.
    pt. A. Structure and mechanisms -- pt. B. Reactions and synthesis.
  • 2006 Thieme eNeurosurgery
    Brockmeyer, Douglas L.
    This text presents state-of-the-art techniques for surgery of the craniovertebral junction and cervical spine. It provides concise explanations of the underlying principles of each technique and insights into the unique issues in pediatric surgery.
  • 2009
    Hamric, Ann B.; Hanson, Charlene M.; Spross, Judith A.
    Status: Not Checked OutLane Catalog Record
    A brief history of advanced practice nursing in the United States / Arlene W. Keeling -- Conceptualizations of advanced practice nursing / Judith A. Spross and Marjorie Thomas Lawson -- A definition of advanced practice nursing / Ann B. Hamric -- Role development of the advanced practice nurse / Karen A. Brykczynski -- Direct clinical practice / Mary Fran Tracy -- Expert coaching and guidance / Judith A. Spross -- Consultation / Anne-Marie Barron and Patricia A. White -- Research / Judith A. DePalma -- Clinical, professional, and systems leadership / Judith A. Spross and Charlene M. Hanson -- Collaboration / Charlene M. Hanson and Judith A. Spross -- Ethical decision making / Ann B. Hamric and Sarah A. Delgado -- The clinical nurse specialist / Patricia S.A. Sparacino and Cathy C. Cartwright -- The primary care nurse practitioner / Ann Reid Anderson and Eileen T. O'Grady -- The acute care nurse practitioner / Marilyn Hravnak ... [et al.] -- The blended role of the clinical nurse specialist and the nurse pracitioner / Patricia M. Hentz and Ann B. Hamric -- The certified nurse-midwife / Cheryl A. Sarton and Maureen A. Kelley -- The certified registered nurse anesthetist / Margaret Faut-Callahan and Michael J. Kremer -- Evolving and innovative opportunities for advanced practice nursing / Jeanne Salyer and Ann B. Hamric -- Business planning and reimbursement mechanisms / Charlene M. Hanson and Sally D. Bennett -- Marketing and contracting considerations / Donna R. Hodnicki -- Understanding regulatory, legal, and credentialing requirements / Charlene M. Hanson -- Health policy issues in changing environments / Eileen T. O'Grady and Jean E. Johnson -- Strengthening advanced practice nursing in organizational structures : administrative considerations / Brenda M. Nevidjon and Cynthia J. Simonson -- Outcomes evaluation and performance improvement : an integrative review of research on advanced practice nursing / Gail L. Ingersoll -- Outcomes evaluation and performance improvement : using data and information technology to improve practice / Vicky A. Mahn-DiNicola.
  • 2006
    Enderle, John D.; Farden, David Charles; Krause, Daniel J.
  • 2011 Springer
    Pease, Shirley; Saunders, Thomas L.
    Patent and licensing issues in transgenic technology / Karen S. Canady -- Global resources : including gene trapped ES cell clones -- is your gene already knocked out / Lluis Montoliu -- Designing transgenes for optimal expression / Eduardo Molto, Cristina Vicente-Garcıa, and Lluis Montoliu -- Gene targeting vector design for embryonic stem cell modifications / Thomas L. Saunders -- Transgenic production benchmarks / Thomas J. Fielder and Lluis Montoliu -- Generation of transgenic mice by pronuclear microinjection / Katja Becker and Boris Jerchow -- Generation of transgenic rats using microinjection of plasmid DNA or lentiviral vectors / Severine Menoret ... [et al.] -- Generation of transgenic animals by use of YACs / Almudena Fernandez, Diego Munoz, and Lluis Montoliu -- BAC transgenes, DNA purification, and transgenic mouse production / Michael G. Zeidler, Margaret L. Van Keuren, and Thomas L. Saunders -- Generation of transgenic animals with lentiviral vectors / Carlos Lois -- Vertebrate transgenesis by transposition / Aron Geurts, Darius Balciunas, and Lajos Mates -- Rat spermatogonial stem cell-mediated gene transfer / Karen M. Chapman ... [et al.] -- Mouse cloning by nuclear transfer / Sayaka Wakayama, Nguyen Van Thuan, and Teruhiko Wakayama -- Gene targeting in embryonic stem cells / Elizabeth D. Hughes and Thomas L. Saunders -- Importance of mouse ES cell line selection / Wojtek Auerbach and Anna B. Auerbach -- Tetraploid complementation assay / Marina Gertsenstein -- Combining ES cells with embryos / Elizabeth Williams ... [et al.] -- Derivation of murine ES cell lines / Kristina Nagy and Jennifer Nichols -- Rat embryonic stem cell derivation and propagation / Ping Li ... [et al.] -- Induced pluripotency : generation of iPS cells from mouse embryonic fibroblasts / Han Li ... [et al.] -- Preparation and analysis of DNA for use in transgenic technology / Anna B. Auerbach, Peter J. Romanienko, and Willie H. Mark -- Colony management / Karen Brennan -- Cryopreservation / B. Pintado and J. Hourcade -- Shipment of mice and embryos / Shirley Pease -- Pathogen-free mouse rederivation by IVF, natural mating and hysterectomy / J.M. Sztein, R.J. Kastenmayer, and K.A. Perdue -- Refinement, reduction, and replacement / Jan Parker-Thornburg.
  • v.1-3=, 2008-2015 Springer Protocols
    v.2 (2010) Springer Protocols
    v.3 (2015) Springer Protocols
    Armstrong, D.
  • 2006 CRCnetBASE
    Peleg, Micha.
  • 2012 Springer
    Erian, Anthony; Shiffman, Melvin A.
  • 2015 Springer
    Borgstrom, David C.; Halverson, Amy L.
    This unique reference fulfills the unmet need of a textbook that addresses the scope of practice for surgeons practicing in rural regions. The text provides up-to-date content covering a wide breadth of topics relevant to surgical care in rural areas, with focus on the surgical diseases that are often treated by surgical subspecialists in the urban setting. Written by experts in each subspecialty, the text focuses on procedural aspects of surgical patient care. The first section discusses practice issues unique to rural surgery and provides an overview of applying principles of quality improvement to surgical practice. Subsequent chapters cover specific surgical procedures. Each chapter includes a brief discussion of indications and contraindications for surgery. The surgical technique is described with attention to important anatomic details. Key portions of the procedure are highlighted including potential complications and how to avoid them. Procedure specific perioperative care is also discussed. Supported with ample illustrations and images, Advanced Surgical Techniques for Rural Surgeons is a valuable resource for surgeons currently in practice or preparing to practice in a rural area, as well as surgical technicians, surgical nurse practitioners, and physician's assistants.
  • 2006 Springer
    Stratton, Charles W.; Tang, Yi-Wei.
  • 2013 Springer
    Stratton, Charles W.; Tang, Yi-Wei.
  • 2002 Thieme eNeurosurgery
    Germano, Isabelle M.
    Machine generated contents note: Contributors vii -- Preface xi -- Dedication x ii -- Acknowledgments xiii --PART I PRINCIPLES AND TECHNOLOGY -- 1. Historical Perspective of Image-Guided Neurosurgery2 -- 2. Sources of Error in Image Registration for Cranial Image-Guided Neurosurgery 10 -- 3. Spinal Registration Accuracy and Error37 -- 4. The Optical Digitizer 45 -- 5. The Mechanical Arm System 54 -- 6. The Magnetic System 60 -- 7. The Passive Navigational System68 -- 8. Image-Guided Neurosurgery Combining Mechanical Arm and Optical Digitizer 73 -- 9. Videotactic Surgery 80 -- 10. Endoscopic Image-Guided Surgery 87 -- 11. Robotic Microscopes 98 -- 12. Image-Guided Robotic Radiosurgery 107 --PART II CRANIAL APPLICATIONS -- 13. Image-Guided Brain Biopsy 116 -- 14. Cerebrovascular Applications of Image-Guided Surgery 121 -- 15. Image-Guided Brain Tumor Resection 132 -- 16. Intraoperative Image Update by Interface with Ultrasound 141 -- 17. Intraoperative Image Update by Magnetic Resonance Imaging 146 -- 18. Image-Guided Epilepsy Surgery 156 -- 19. New Directions in Atlas-Assisted Stereotactic Functional Neurosurgery 162 --PART III SPINAL APPLICATIONS -- 20. Image-Guided Cervical Instrumentation 176 -- 21. Thoracic Instrumentation: Stereotactic Navigation for Placementof Pedicle Screws in the Thoracic Spine 182 -- 22. Image Guidance for Scoliosis 191 -- 23. Image-Guided Lumbar Instrumentation 197 -- 24.Computer-Assisted Image-Guided Fluoroscopy (Virtual Fluoroscopy) 207 -- 25. Controversies in Image-Guided Spine Surgery218 --Index 224.
  • 2015 Springer
    Eralp, Levent; Kocaoğlu, Mehmet; Tsuchiya, Hiroyuki.
    As a result of recent advances in surgical techniques and implant technology it is now possible to perform limb reconstruction in patients with a range of congenital, posttraumatic, and postinfection pathologies. This book is a clear, practical guide to the state-of-the-art surgical procedures employed in limb reconstruction for diverse conditions. It includes precise descriptions of the techniques themselves, accompanied by numerous helpful drawings and photographs. Pearls and pitfalls are highlighted, and thorough advice is also provided on indications, preoperative planning, and postoperative follow-up. The editors have carefully selected the contributors based on their expertise, and many of the authors were themselves responsible for developing the techniques that they describe.
  • 2015 Springer
    Bardakcioglu, Ovunc.
    This book bridges gap between the practicing community of surgeons and the surgical innovators, and it provides a foundation for all classic and new techniques in minimally invasive colorectal surgery. It provides tips and tricks that allow the user to move up the learning curve, manage difficult scenarios, overcome challenges, increase the utilization of minimal invasive techniques and decrease the conversion to open surgery. By enhancing the surgical tool box, the surgeon will be able to progress from the novice to the master. Rather than describing operative procedures, which may be very biased by an individual author, the guide provides alternative building blocks of various difficulty for different procedures, thereby allowing the surgeon to tailored surgery to patient and surgeon's own comfort level and experience. Advanced Techniques in Minimally Invasive and Robotic Colorectal Surgery is an inspirational guide for the innovator of the future. This text allows surgeons of all levels to better adapt to inevitable changes in future techniques. Advanced Techniques in Minimally Invasive and Robotic Colorectal Surgery is of great value to general surgeons, colon and rectal surgeons, minimally invasive surgeons as well as residents and fellows.
  • 2016 Karger
    Cappa, Marco; Cianfarani, Stefano; Ghizzoni, Lucia; Loche, Sandro; Maghnie, Mohamad.
    Toward automation of insulin delivery : management solutions for type 1 diabetes / Nimri, R., Phillip, M. -- Islet transplantation in pediatric patients : current indications and future perspectives / Bertuzzi, F., Antonioli, B., Tosca, M.C., Galuzzi, M., Bonomo, M., Marazzi, M., Colussi, G -- Glucagon-like peptide-1 receptor agonist treatment for pediatric obesity / Kelly, A.S -- Docosahexaenoic acid and its role in g-protein-coupled receptor 120 activation in children affected by nonalcoholic fatty liver disease / Della Corte, C., Mosca, A., Ionata, A., Nobili, V -- Noninvasive prenatal diagnosis of congenital adrenal hyperplasia / Khattab, A., Yuen, T., Sun, L., Yau, M., Barhan, A., Zaidi, M., Lo, Y.M.D., New, M.I -- Recent advances in hydrocortisone replacement treatment / Mallappa, A., Debono, M -- Experience with the histrelin implant in pediatric patients / Eugster, E.A -- Different medications for hypogonadotropic hypogonadism / Rastrelli, G., Vignozzi, L., Maggi, M -- Long-acting growth hormone : an update / Saenger, P.H., Mejia-Corletto, J -- C-type natriuretic peptide analog as therapy for achondroplasia / Legeai-Mallet, L -- Therapeutic neuroendocrine agonist and antagonist analogs of hypothalamic neuropeptides as modulators of the hypothalamic-pituitary-gonadal axis / Newton, C.L., Anderson, R.C., Millar, R.P -- Aromatase inhibitors in the treatment of short stature / Hero, M -- Gene therapy for rare central nervous system diseases comes to age / Aubourg, P -- Novel therapeutic targets and drug candidates for modifying disease progression in adrenoleukodystrophy / Pujol, A.
  • 2006
    Mohler, Emile R.; Townsend, Raymond R.
    Status: Not Checked OutLane Catalog Record
  • 2012 ScienceDirect
    Butler, John M.
    Intended as a companion to the Fundamentals of Forensic DNA Typing volume published in 2009, Advanced Topics in Forensic DNA Typing: Methodology contains 18 chapters with 4 appendices providing up-to-date coverage of essential topics in this important field and citation to more than 2800 articles and internet resources. The book builds upon the previous two editions of John Butler's internationally acclaimed Forensic DNA Typing textbook with forensic DNA analysts as its primary audience. This book provides the most detailed information written to-date on DNA databases, low-level DNA, validation, and numerous other topics including a new chapter on legal aspects of DNA testing to prepare scientists for expert witness testimony. Over half of the content is new compared to previous editions. A forthcoming companion volume will cover interpretation issues. Contains the latest information - hot-topics and new technologies Well edited, attractively laid out, and makes productive use of its four-color format Author John Butler is ranked as the number one "high-impact author in legal medicine and forensic science, 2001 to 2011" by ScienceWatch.com.
  • Caponetto, R.; Fortuna, L.; Frasca, Mattia.
  • 2014 Springer
    Darie, Costel C.; Woods, Alisa G.
    "This volume explores the use of mass spectrometry for biomedical applications. Chapters focus on specific therapeutic areas such as oncology, infectious disease and psychiatry. Additional chapters focus on methodology as well as new technologies and instrumentation. This volume provides readers with a comprehensive and informative manual that will allow them to appreciate mass spectrometry and proteomic research but also to initiate and improve their own work. Thus the book acts as a technical guide but also a conceptual guide to the newest information in this exciting field. Mass spectrometry is the central tool used in proteomic research today and is rapidly becoming indispensable to the biomedical scientist. With the completion of the human genome project and the genomic revolution, the proteomic revolution has followed closely behind. Understanding the human proteome has become critical to basic and clinical biomedical research and holds the promise of providing comprehensive understanding of human physiological processes. In addition, proteomics and mass spectrometry are bringing unprecedented biomarker discovery and are helping to personalize medicine"--Publisher's description.
    Also available: Print – 2014
  • 2011
    John, Thomas S.; Glover, Gary H.; Nishimura, Dwight George; Pauly, John M.
    Magnetic resonance imaging (MRI) is a versatile imaging tool that can be used to detect changes in brain hemodynamics that accompany neuronal activity. This ability to observe both anatomy and the structures that participate in specific functions is often referred to as functional magnetic resonance imaging (fMRI). Echo planar imaging (EPI) is the most widely used data acquisition method for fMRI. Functional images are often distorted because EPI is highly sensitive to field inhomogeneities, eddy currents, and gradient delays. These distortions often lead to image misregistration, and this is an impediment to correctly interpreting functional studies, and to neurosurgical planning. Many methods have been developed to address this. However, none yields anatomical and functional images that may be directly overlaid onto each other with no post-processing. This dissertation demonstrates that automatic, inherent self co-registration is achieved when optimized flyback EPI with echo time shifting (ETS) is used for both functional and anatomical images. fMRI experiments validate the proposed method, and the result is high-quality functional and high-resolution anatomical images that are inherently self co-registered. EPI acquisitions are also prone to timing and phase errors that give rise to image ghosting. ETS is an effective ghost correction method in EPI. Although ETS corrects for ghosting in a robust, non-iterative, and automatic manner, it does so at the expense of increasing total scan time. This dissertation proposes a simple, yet effective scheme to increase the efficiency of ETS by acquiring partial echoes during the idle wait times present in ETS. Using the proposed technique, higher resolution images are acquired when total scan time is fixed. Alternately, shorter scan times are possible when the in-plane resolution is fixed. Equations that predict the expected improvement in resolution are derived and shown to be accurate through simulations and experiments. In vivo images obtained using conventional ETS and the proposed method show that the time savings obtained with the proposed method do not result in any visible degradation in image quality. Signal changes caused by cardiac pulsation and respiratory fluctuation are also a major confound in fMRI. These time-locked signal changes, also referred to as "physiological noise, " decrease the sensitivity of fMRI to neuronally-induced signal fluctuations. To date, no method exists that compensates for these detrimental effects in 3D fMRI acquisitions. This dissertation presents a novel algorithm that compensates for physiological noise in 3D echo-planar fMRI. The proposed method utilizes composite property mapping and efficient root-solving to estimate physiologically-induced signal fluctuations in 3D k-space data. These signal fluctuations are subsequently regressed from k-space data. Results show that the estimated signal fluctuations have significant power in the cardiac and respiratory frequency bands. Further, resting-state fMRI experiments show an increase in the number of activated voxels when the proposed compensation algorithm is employed. This is accompanied by an increase in the average z-score of activated voxels, and a more Gaussian distributed voxel time-course. In conclusion, this dissertation describes advances in data acquisition and post- processing in 3D fMRI that are easy to implement. Further, promising experimental results suggest the efficacy of all the proposed methods.
  • 2012 Future Med
    White, Harvey.
    Advances in acute coronary syndrome management / Harvey White -- Etiology and overview / Ralph A.H. Stewart -- Biomarkers in acute coronary syndromes / Harvey D. White -- Clinical risk scores in ACS management : current and future directions / Derek P. Chew & Leong Lee -- Antithrombotic therapies / Paul A. Gurbel & Udaya S. Tantry -- Lipid-lowering therapy / Joel A. Lardizabal & Prakash C. Deedwania -- Antihypertensive therapies / Grégoire Wuerzner, Olivier Muller & Michel Burnier -- Interventional approaches to acute coronary syndromes / Neal S. Kleiman -- Noninvasive imaging in acute coronary syndromes / Govind Srinivasan & Joseph Selvanayagam -- Electrocardiography in acute coronary syndromes / Cheuk-Kit Wong & Harvey D. White -- Current guidelines for acute coronary syndromes / Michel E. Bertrand -- Index.
  • 2006 Springer
    Stevenson, R. Jan.
  • 2008 Springer
    Fisher, Abraham; Hanin, Israel; Memo, Maurizio; Stocchi, F.
    The subject matter of the ADPD conferences is unique in that it deals not only with issues related individually to Alzheimer's disease and Parkinson's disease, but also with the integration of these and other related diseases. The most up-to-date techniques and research findings are illustrated in this volume.
  • 2012 Future Med
    Gauthier, Serge; Rosa-Neto, Pedro.
    Advances in Alzheimer's disease management / Serge Gauthier & Pedro Rosa-Neto -- Genetics of Alzheimer's disease / Jayashree Viswanathan, Hilkka Soininen & Mikko Hiltunen -- Diagnosis of Alzheimer's disease / Pedro Rosa-Neto, Jared Rowley, Antoine Leuzy, Sara Mohades, Monica Shin, Marina T. Dauar & Serge Gauthier -- Available symptomatic antidementia drugs / Marie-Pierre Thibodeau & Fadi Massoud -- New drugs under development for Alzheimer's disease / Lezanne Ooi, Kirubakaran Shanmugam, Mili Patel, Rachel Debono & Gerald Münch -- Management of agitation and aggression : controversies and possible solutions / Clive Ballard & Anne Corbett -- Guidelines for the diagnosis and treatment of Alzheimer's disease / Serge Gauthier & Christopher J.S. Patterson -- Ethical and clinically humane end-of-life care for those living with dementia / Michael Gordon -- Index.
  • 2014 Future Med
    Moneret-Vautrin, Denise Anne.
    Advances in anaphylaxis management / Denise Anne Moneret-Vautrin -- Anaphylaxis : classification and clinical symptoms / Johannes Ring, Jarmila Liptak & Knut Brockow -- Pathophysiology : IgE-mediated and non-IgE-mediated anaphylaxis / Denise Anne Moneret-Vautrin -- Risk factors for fatal anaphylaxis / Richard Pumphrey & Gunter Sturm -- Etiologies of anaphylaxis / Margitta Worm -- Biomarkers for the evaluation of severity of anaphylaxis / Julia Upton & Peter Vadas -- Role of specific IgE testing in allergy diagnosis / Sandrine Jacquenet, Denise-Anne Moneret-Vautrin & Bernard E. Bihain -- Treatment algorithm for anaphylaxis and prognosis / Ben Gibbison & Jasmeet Soar -- Food anaphylaxis prevention / Martine Morisset -- Hymenoptera anaphylaxis : indications and results of immunotherapy / Ulrich R. Müller & Arthur Helbling -- Index.
  • v. 177-, 2005- Springer
  • 2011 Future Med
    Patsalos, P. N.
    Advances in antiepileptic drug development / Philip N. Patsalos -- Current guidelines and standard treatments / Dieter Schmidt & G{uml}unter Kr{uml}amer -- Advances in screening models for identifying new antiepileptic drugs / Kinga K. Borowicz & Stanislaw J. Czuczwar -- New antiepileptic drugs : advances in pharmacokinetics, drug interaction and adverse effect profiles / Domenico Italiano & Edoardo Spina -- Antiepileptic drugs in clinical trials and future direction / Alberto Verrotti, Chiara Cirillo & Giulia Loiacono.
  • 2013 Wiley
    Colombo, Paolo; Narayan, Roger.
  • v. 2-, 2007- Springer
    Dhalla, Naranjan S.
  • 2008 CRCnetBASE
    Kendall, Ronald J.
    State of the science : background, history, and current threats / Steven M. Presley, Chris B. Pepper, Galen P. Austin, Ronald J. Kendall -- Threats and vulnerabilities associated with biological and chemical terrorism / Steven M. Presley, Galen P. Austin, Phil N. Smith, John White, Ronald J. Kendall -- Predicting and characterizing threat transport / Jeremy W. Leggoe, Chia-bo Chang, Stephen B. Cox, Steven M. Presley, Richard Zartman -- Assessment strategies for environmental protection from chemical and biological threats / Richard Zartman, Chai-Bo Chang, George P. Cobb, Joe Fralick, Steven M. Presley -- Chemical threat agent-induced latent (delayed) neurodegeneration / Jean Strahlendorf and Howard Strahlendorf -- Sensing biological and chemical threat agents / Gopal Coimbatore, Steven M. Presley, Jonathan Boyd, Eric J. Marsland, and George P. Cobb -- Phage display and its application for the detection and therapeutic intervention of biological threat agents / Joe A. Fralick and Prabhjit Chadha-Mohanty -- Personnel protective fabric technologies for chemical countermeasures / Seshadri Ramkumar, Utkarsh Sata, and Munim Hussain -- Pathogenic and toxic effects of select biological threat agents / Jia-Sheng Wang -- Conclusions and research needs for the future / Ronald J. Kendall, Galen P. Austin, Chia-bo Chang, George P. Cobb, Gopal Coimbatore, Stephen B. Cox, Joe A. Fralick, Jeremy W. Leggoe, Steven M. Presley, Seshadri S.Ramkumar, Philip N. Smith, Jean C. Strahlendorf, and Richard E. Zartman.
  • 2013 Springer
    Anderson, Kenneth C.; Munshi, Nikhil C.
    Despite the advances in conventional, and novel agent and high dose chemotherapy, multiple myeloma remains incurable. In order to overcome resistance to current therapies and improve patient outcome, novel biologically-based treatment approaches are being developed. Current translational research in multiple myeloma focusing on the development of molecularly-based novel targeted single-agent and combination therapies has great promise to achieve high frequency and durable responses in the majority of patients. This volume will focus on biology of multiple myeloma, especially on oncogenomic changes, cell signaling pathways and intermediate molecules that are being investigated for development of novel therapies. The book will present newer developments, providing an emphasis on basic science, as well as its significant clinical impact.
  • 2013 Springer
    Anderson, Kenneth C.; Munshi, Nikhil C.
    Despite the advances in conventional, and novel agent and high dose chemotherapy, multiple myeloma remains incurable. In order to overcome resistance to current therapies and improve patient outcome, novel biologically-based treatment approaches are being developed. Current translational research in multiple myeloma focusing on the development of molecularly-based novel targeted single-agent and combination therapies has great promise to achieve high frequency and durable responses in the majority of patients. This volume will focus on biology of multiple myeloma, especially on oncogenomic changes, cell signaling pathways and intermediate molecules that are being investigated for development of novel therapies. The book will present newer developments, providing an emphasis on basic science, as well as its significant clinical impact.
  • 1980-
    Cooney, David O.
    Status: Not Checked OutLane Catalog Record
  • 2007 CRCnetBASE
    Baust, J. G.; Baust, John M.
  • 2012 Future Med
    De Ruggieri, Pietro; Picci, Piero.
    Advances in bone metastasis management / Piero Picci & Pietro Ruggieri -- Pathways to metastases : how do metastases develop in bone / Jeff Toreson & Robert E. Turcotte -- Metastatic spread to bone : the role of chemotherapy / Stefano Ferrari, Emanuela Palmerini, Andreas F. Mavrogenis & Pietro Ruggieri -- Bone stroma inhibition in prostate cancer / Michael A. Carducci & Daniel Keizman -- Management of bone metastases in breast cancer / Toni Ibrahim & Dino Amadori -- Radiotherapy for bone metastases / Julia Di Giovanni, Janet Nguyen, Marko Popovic & Edward Chow -- Bisphosphonates for bone metastases / Esther Chan & Urban Emmenegger -- Surgical treatment for spinal metastases / Roberto Casadei, Andreas F. Mavrogenis, Marco Manfrini & Pietro Ruggieri -- Surgical treatment for pelvic bone metastases / Andreas F Mavrogenis, Eugenio Brunocilla, Giuseppe Bianchi, Nicola Fabbri & Pietro Ruggieri -- Surgical treatment for metastatic pathological fractures / Andreas F. Mavrogenis, Roberto Casadei & Pietro Ruggieri -- Palliative treatments : selective arterial embolization for bone metastases / Giuseppe Rossi, Andreas F. Mavrogenis, Piero Picci & Pietro Ruggieri -- Palliative treatments : electrochemotherapy and thermoablation / Giuseppe Bianchi, Laura Campanacci, Eugenio Rimondi & Pietro Ruggieri -- Novel targeted therapies of bone tumors and future directions / Dominique Heymann -- Index.
  • 2008 Springer
    Gradishar, William J.; Wood, William C.
    Also available: Print – 2008
  • 2010
    Rakow-Penner, Rebecca; Daniel, Bruce L.; Glover, Gary H.; Hargreaves, Brian A.
    Breast magnetic resonance imaging (MRI) is becoming an increasingly valuable technology for breast cancer detection, especially for women at high risk for the disease. Stanford Hospital alone performed approximately 1,000 breast MRIs last year. This demand and need to increase specificity of breast MRI motivates improving current breast MR protocols, as well as exploring new applications of MR technology to breast imaging. Most clinical breast MR exams are performed at a 1.5T field strength. 3T scanners, however, are becoming more prevalent in the clinical setting and thus the breast MR protocol needs to be tuned accordingly. The first project includes measurements of T1 and T2 of breast fat and glandular tissue at 1.5T and 3T and the corresponding recommendation for altering the TR and TE for 3T breast imaging. The beating heart posterior to the breast often produces artifacts in breast MR images. The second project is a cylindrical saturation method that reduces unwanted signal from the heart while avoiding signal loss from the breast tissue of interest. Detecting tumor oxygenation non-invasively may give insight on tumor differentiation, predict susceptibility to antiangiogenic therapeutics, and monitor chemotherapeutics. The third project introduces the application of BOLD contrast imaging, a technique usually applied in functional brain MR imaging for characterizing tumor oxygenation in the breast.
  • 2015 Springer Protocols
    Scatena, Roberto.
    "At present there are a growing number of biomolecules under investigation to understand their potential role as cancer biomarker for diagnostic, prognostic and therapeutic purposes. Intriguingly, the state of art on cancer biomarkers research shows interesting and promising results together to clamorous failures. Also from a clinical point of view, there are contradictory results on routine clinical use of the present cancer biomarkers. Some patients may be simply monitored in their course by a periodic blood sample, but sometimes this monitoring shows dramatic limits. A lot of patients show serious and extensive relapses without significant change in serum concentrations of biomarkers tested. Often the physician who should utilize these biomarker does not entirely know their limits and the total potential applications as well and sometimes this knowledge is influenced by economical and marketing strategies. This limited and "polluted" knowledge may have dramatic consequences for patient. The aim of this book is to diffuse all aspects of cancer biomarkers, from their biochemical peculiarities to all clinical implications by passing through their physiology and pathophysiology. This critical approach towards old and new cancer biomarkers should foster a deepened and useful understanding of the diagnostic and prognostic index of these fundamental parameters of laboratory medicine and in the same time facilitating the research of new and more sensitive-specific signals of the cancer cell proliferation"--Back cover.
    Also available: Print – 2015
  • 2012 Springer
    Giardina, B.; Mordente, Alvaro; Scatena, Roberto.
    1. Cancer Stem Cells: A Revisitation of the "Anaplasia" Concept / Roberto Scatena -- 2. Stem Cells and Cancer Stem Cells: New Insights / Toru Kondo -- 3. Molecular Biology of Cancer Stem Cells / Oswaldo Keith Okamoto -- 4. Biomarkers of Cancer Stem Cells / Jun Dou and Ning Gu -- 5. Cancer Stem Cells and the Microenvironment / Alfonso Colombatti, Carla Danussi, Eliana Pivetta, and Paola Spessotto -- 6. Leukemia Stem Cells / Steven W. Lane and David A. Williams -- 7. Cancer Stem Cells and the Central Nervous System / Serdar Korur, Maria Maddalena Lino, and Adrian Merlo -- 8. Cancer Stem Cells and Glioblastoma Multiforme: Pathophysiological and Clinical Aspects / Akio Soeda, Mark E. Shaffrey, and Deric M. Park -- 9. Breast Cancer Stem Cells / Nuria Rodríguez Salas, Enrique González González, and Carlos Gamallo Amat -- 10. Colon Cancer Stem Cells / Ugo Testa -- 11. Liver Tumor-Initiating Cells/Cancer Stem Cells: Past Studies, Current Status, and Future Perspectives / Kwan Ho Tang, Stephanie Ma, and Xin-Yuan Guan -- 12. Pancreatic Cancer Stem Cells / Erica N. Proctor and Diane M. Simeone -- 13. Cancer Stem Cells and Renal Carcinoma / Benedetta Bussolati and Giovanni Camussi -- 14. Cancer Stem Cells: Proteomic Approaches for New Potential Diagnostic and Prognostic Biomarkers / Patrizia Bottoni, Bruno Giardina, and Roberto Scatena -- 15. Cancer Stem Cells: An Innovative Therapeutic Approach / Roberto Scatena, Patrizia Bottoni, Alessandro Pontoglio, Salvatore Scarà, and Bruno Giardina -- 16. Cancer Stem Cell and ATP-Binding Cassette: Which Role in Chemoresistance? / Andrea Silvestrini, Elisabetta Meucci, Giuseppe Ettore Martorana, Bruno Giardina, and Alvaro Mordente -- 17. Stem Cells and Cancer Stem Cells: Biological and Clinical Interrelationships / Cinzia Bagalà and Carlo Barone -- 18. Immunomodulatory Functions of Cancer Stem Cells / Tobias Schatton, Jennifer Y. Lin, and Markus H. Frank.
  • 2015 Springer
    Foxhall, Lewis E.; Rodriguez, M. Alma.
    This volume presents the MD Anderson experience in providing care and services to the rapidly growing population of cancer survivors, which is currently estimated to be 12 million in the United States and more than 25 million worldwide. As cancer survival rates have increased, it has slowly become clear that the challenges faced by people with cancer do not end with treatment but simply change. This book aims to assist community oncologists, physicians, and their staff, who care for the vast majority of cancer survivors, by disseminating models of surveillance for disease recurrence, screening for second primary cancers, education regarding potential late effects of treatment, and psychosocial counseling. These models have proven valuable to cancer survivors who receive care at MD Anderson.
  • 2007 Springer
    Acharya U, Rajendra.
  • 2013 Springer
    Malek, Sami N.
    Chronic lymphocytic leukemia (CLL) is the most common leukemia in the Western world. CLL has a highly varied clinical course. While advances in CLL therapy are noted, many patients still succumb to this illness. Like most progress in medicine, solid advances in the diagnosis, prognosis and treatment of CLL are rooted in an in-depth understanding of the basic and translational biology of CLL. In this book, CLL experts have contributed state-of-the-art summaries of various important aspects of CLL biology and have discussed the translational implication of such findings. This book, which is directed at physicians and researchers alike, aims to educate broadly and deeply. Intentionally, the many aspects and nuances of CLL clinical care that can only really be appreciated through direct patient care are not covered here, but instead, the book presents basic aspects of CLL that underlie many of the contemporary decisions that are made in CLL research and clinical settings. We hope that this book will critically inform the community and stimulate interest in CLL, which will ultimately translate into better CLL research, prognostication and therapy, with the end goal of providing a better outlook for patients afflicted with this common leukemia.
    Also available: Print – 2013
  • 2016 Springer
    Pokorski, Mieczyslaw.
    Prevalence of olfactory impairment in granulomatosis with polyangiitis -- Biochemistry of oxidative stress -- Usage of over-the-counter and herbal products in common cold in Poland: findings from consumer survey -- RARβ promoter methylation as an epigenetic mechanism of gene silencing in non-small cell lung cancer -- Cardiovascular risk factors in obese children and adolescents -- Nutrition and immune system in children with simple obesity -- The influence of shockwave therapy on orthodontic tooth movement induced in the rat -- Thyroid hormone levels and TSH activity in patients with obstructive sleep apnea syndrome -- Age and gender-related changes in biogenic amine metabolites in cerebrospinal fluid in children -- The influence of primary cytomegalovirus or Epstein-Barr virus infection on the course of idiopathic thrombocytopenic purpura -- Index.
    Also available: Print – 2016
  • 2012 CRCnetBASE
    Hale, Kelly S.; Stanney, Kay M.
    "Preface This book brings together a wide-ranging set of contributed articles that address emerging practices and future trends in cognitive engineering and neuroergonomics. Both aim to harmoniously integrate human operator and computational system, the former through a tighter cognitive fit and the latter a more effective neural fit with the system. The chapters in this book uncover novel discoveries and communicate new understanding and the most recent advances in the areas of workload and stress, activity theory, human error and risk, and neuroergonomic measures, as well as associated applications.-- Provided by publisher.
  • 2011 Springer
    Gu, Fanji; Wang, Rubin.
    Within our knowledge, the series of the International Conference on Cognitive Neurodynamics (ICCN) is the only conference series dedicating to cognitive neurodynamics. This volume is the proceedings of the 2nd International Conference on Cognitive Neurodynamics held in 2009, which reviews the progress in this field since the 1st ICCN -2007. The topics include: Neural coding and realistic neural network dynamics, Neural population dynamics, Firing Oscillations and Patterns in Neuronal Networks, Brain imaging, EEG, MEG, Sensory and Motor Dynamics, Global cognitive function, Multi-scalar Neurodyn
  • 2013 Springer
    Yamaguchi, Yoko.
    This book contains the Proceedings of the 3rd International Conference on Cognitive Neurodynamics held in Japan, June 9-13, 2011. It reviews the progress in this field since the first ICCN in 2007. The participants were treated to an exciting and stimulating conference that left everyone with an enthusiastic vision for the future. The discussed topics in this book include: Neural coding and realistic neural network dynamics, Neural population dynamics, Firing Oscillations and Patterns in Neuronal Networks, Brain imaging, EEG, MEG, Sensory and Motor Dynamics, Global cognitive function, Multi-scalar Neurodynamics - from Physiology to Systems Theory, Neural computing, Emerging Technologies for Brain Computer Interfaces, Neural dynamics of brain disorders.
  • 2013 Springer
    Collins, Chiquita Ann; Pasch, Keryn E.; Williams, Jerome D.
    Overview, The IOM Report, and Integrated Marketing Communications -- Introduction: Childhood Obesity: Media, Advertising, Community, and Advocacy -- Progress on Public Policy: The Aftermath of the 2005 Institute of Medicine Report on Food Marketing and the Diets of Children and Youth -- Integrated Marketing Communications and Power Imbalance: The Strategic Nature of Marketing to Children and Adolescents by Food and Beverage Companies -- Legal, Ethical, and Policy Implications of Advertising -- The Role of Ethics in Food and Beverage Marketing to Children -- The New First Amendment and Its Implications for Combating Obesity Through Regulation of Advertising -- Self-regulation as a Tool for Promoting Healthier Children's Diets: Can CARU and the CFBAI Do More? -- Monitoring Food Company Marketing to Children to Spotlight Best and Worst Practices -- Measuring the Impact of Advertising Effects -- Children's Exposure to Food and Beverage Advertising on Television: Tracking Calories and Nutritional Content by Company Membership in Self-regulation -- The Role of Advertising on Attitudes and Consumption of Food and Beverage Products -- The Digital Food Marketing Landscape: Challenges for Researchers -- A Multi-Method Study to Understand How Youth Perceive and Evaluate Food and Beverage Advertisements -- A Global Perspective of Food Marketing and the Role of Place -- Adolescents' Response to Food Marketing in Delhi, India -- The Role of Schools in Food and Beverage Marketing: Significance, Challenges, Next Steps -- Outdoor Food and Beverage Advertising: A Saturated Environment -- Exploring Marketing Targeted at Youth in Food Stores -- Racial/Ethnic Minorities and Community Empowerment -- Understanding Community Perspectives: A Step Towards Achieving Food Marketing Equity -- Latino Youth and Obesity: Communication/Media Influence on Marketing -- Targeted Marketing of Junk Food to Ethnic Minority Youth: Fighting Back with Legal Advocacy and Community Engagement -- Communicating About Physical Activity -- Physical Activity, Media, and Marketing: Advances in Communications and Media Marketing -- Communities Leveraging the Assets of a National Social Marketing Campaign: Experiences with VERB[TM]. It's What You Do! -- Development and Release of the 2008 Physical Activity Guidelines for Americans: Children and Adolescents -- Thinking Outside the Box: Finding Solutions to Reverse Childhood Obesity -- Voluntary Health Organizations and Nonprofit Advocacy Organizations Play Critical Roles in Making Community Norms More Supportive of Healthier Eating and Increased Physical Activity -- Childhood Obesity and Exergames: Assessments and Experiences from Singapore -- Leveraging Industry Efforts to Fight Childhood Obesity: A Multi-Sectored Approach to Communications.
  • 2010 Springer
    Arabnia, Hamid R.
    Bioinformatics databases, data mining, and pattern discovery -- Microarray, gene expression analysis, and gene regulatory networks -- Protein classification & structure prediction, and computational structural biology -- Comparative sequence, genome analysis, genome assembly, and genome scale computational methods -- Drug design, drug screening, and related topics -- Computational methods and diagnostic tools in biomedical -- General topics in bioinformatics.
    Also available: Print – 2010
  • v. 2, ? CRCnetBASE
    Adlof, R. O.; Christie, William W.; Sebedio, J.-L.
    v. 2. Chapter 1. Analysis of Conjugated Linoleic Acid: An Overview / William W. Christie -- Chapter 2. Gas Chromatography-Mass Spectrometry of Conjugated Linoleic Acids and Metabolites / Gary Dobson -- Chapter 3. Application of Silver-Ion Chromatography to the Separation of Conjugated Linoleic Acid Isomers / Richard O. Adlof -- Chapter 4. Oxidation of Conjugated Linoleic Acid: Initiators and Simultaneous Reactions: Theory and Practice / Martin P. Yurawecz, Pierluigi Delmonte, Torben Vogel,
  • 2014 Springer
    Farghaly, Samir A.
    This volume is an up-to-date resource on the international state-of-the-art in the diagnosis and management of ovarian cancer. While this devastating disease has been considered mainly a disease of the Western hemisphere, the book moves beyond our conventional understanding and embraces knowledge from around the world. It focuses on recent advances in diagnosis, including genetic screening; improvements and expanded choices in management, such as gene therapy and the optimization of chemotherapeutic agents; and the latest laparoscopic and robotic surgical techniques. Further chapters address histopathologic features of this disease, and related psychosocial and quality of-life-issues. The book is aimed at the wide range of practitioners who care for patients with ovarian cancer and researchers who study the disease: general surgeons, surgical oncologists, gynecological oncologists, medical oncologists, pediatric oncologists, gynecological pathologists, gynecologists, gynecological cancer epidemiologists, gynecological onco-psychologist, genetic counselors, geneticists, and cancer research scientists.
  • 2006 Springer
    Bolondi, L.
  • 2013 Springer
    Alaoui-Jamali, Moulay A.; Aloyz, Raquel; Panasci, Lawrence C.
    Repair of DNA Interstrand Cross-links Produced by Cancer Chemotherapeutic Drugs / Anderson T. Wang, Peter J. McHugh -- DNA-PK, a Pharmacological Target in Cancer Chemotherapy and Radiotherapy? / Bernard Salles D.V.M., Ph.D. -- Growth Factor Receptor Signaling, DNA Damage Response, and Cancer Cell Susceptibility to Chemotherapy and Relapses / Moulay Alaoui-Jamali, Amine Saad, Gerald Batist -- The Relationship Between DNA-Repair Genes, Cellular Radiosensitivity, and the Response of Tumors and Normal Tissues to Radiotherapy / David Murray, Matthew Parliament -- Important Roles of ERCC1 in DNA Repair and Targeted Therapy / Jennifer J. Hu, Joseph de la Garza -- The Role of BRCA1 and BRCA2 in Anticancer Drug Therapy / Andrew Y. Shuen, Jorge S. Reis-Filho -- DNA-PK in CLL Chemotherapy / L. Amrein, D. Davidson, R. Aloyz, L. Panasci -- Poly(ADP) Ribose Polymerase at the Interface of DNA Damage Signaling and DNA Repair / Jana Krietsch, Michele Rouleau, Michel Lebel -- Cellular Protection Against the Antitumor Drug Bleomycin / Dindial Ramotar Ph.D., Mustapha Aouida Ph.D. -- ATR as a Therapeutic Target / Fiona K. Middleton, Nicola J. Curtin -- Telomeres, Telomerase, and DNA Damage Response in Cancer Therapy / Raina A. Tamakawa, Helen B. Fleisig -- RAD51 Is a Key Protein of DNA Repair and Homologous Recombination in Humans / Alexander V. Mazin Ph.D., Olga M. Mazina.
  • 2014 Future Med
    Aronow, Wilbert S.
    Advances in dyslipidemia / Wilbert S. Aronow -- Atherosclerosis : dyslipidemia, inflammation and lipoapoptosis / Fleur M. van der Valk, Dominik M. Schulte, Willem J.M. Mulder & Erik S.G. Stroes -- Familial hypercholesterolemia : bridging and minding the gap in healthcare / Jing Pang, Alistair W. Vickery & Gerald F. Watts -- PCSK9 inhibition : drug development for low-density lipoprotein lowering / Geetha Mukerji, Rawand M. Abdin & Dominic S. Ng -- Novel therapies for dyslipidemia / Anthony S. Wierzbicki -- The highs and lows of high-density lipoprotein / Daniel Soffer & Marisa Schoen -- Do we need to treat patients with heart failure with statins? / Sadip Pant, Guru S. Gurumurthy, Abhishek Deshmukh & Jawahar L. Mehta -- Management of dyslipidemia in patients with nonalcoholic fatty liver disease / Konstantinos Tziomalos, Vasilios G. Athyros & Asterios Karagiannis -- Dyslipidemia : current management and the challenge of residual cardiovascular risk reduction / Aaron Rockoff, Vaijinath S. Kamanna & Moti L. Kashyap -- Index.
  • v. 1-2, 1972-76.
    Abildskov, J. A.; Hurst, J. Willis; Schlant, Robert C.
    Status: Not Checked OutLane Catalog Record
  • 2014 Springer
    Gange, A. C.; Verma, Vijay.
    In recent years there has been significant attention paid on the endophytic research by various groups working within this domain. Mutualistic endophytic microbes with an emphasis on the relatively understudied fungal endophytes are the focus of this special book. Plants are associated with micro-organisms: endophytic bacteria and fungi, which live inter- and intra-cellularly without inducing pathogenic symptoms, but have active biochemical and genetic interactions with their host. Endophytes play vital roles as plant growth promoters, biocontrol agents, biosurfactant producers, enzymes and secondary metabolite producers, as well as providing a new hidden repertoire of bioactive natural products with uses in pharmaceutical, agrochemical and other biotechnological applications. The increasing interest in endophytic research generates significant progress in our understanding of the host-endophyte relationship at molecular and genetic level. The bio-prospection of microbial endophytes has led to exciting possibilities for their biotechnological application as biocontrol agent, bioactive metabolites, and other useful traits. Apart from these virtues, the microbial endophytes may be adapted to the complex metabolism of many desired molecules that can be of significant industrial applications. These microbes can be a useful alternative for sustainable solutions for ecological control of pests and diseases, and can reduce the burden of excess of chemical fertilizers for this purpose. This book is an attempt to review the recent development in the understanding of microbial endophytes and their potential biotechnological applications. This is a collection of literature authored by noted researchers having signatory status in endophytic research and summarizes the development achieved so far, and future prospects for further research in this fascinating area of research.
  • 2013 Springer
    Pletschke, Brett; Shukla, Pratyoosh.
    Improvement of thermostable enzyme with sugar metabolic activity by targeted mutagenesis -- Glycoside hydrolases for modification of glycosylation in polyphenolic antioxidants -- On the enzyme specificity for the synthesis of prebiotic galacto-oligosaccharides -- Microbial mannanases: properties and applications -- Enzyme Synergy for Enhanced Degradation of Lignocellulosic Waste -- Manganese peroxidase: molecular diversity, heterologous expression and applications -- Advance Techniques in Enzyme Research -- Regulatory motif identification in biological sequences: An overview of computational methodologies -- Structural, Molecular and Functional Aspects of Chitin deacetylase -- Role of enzymes and proteins in plant -- microbe interaction : A study of M. oryzae vs Rice -- Industrial enzyme applications in biorefineries for starchy materials.
  • 2014 Springer
    Ducsay, Charles Andrew; Zhang, Lubo.
    "To celebrate the Center for Perinatal Biology's 40th Anniversary, an illustrious group gathered at Loma Linda University in February 2013. That gathering of experts and this volume of the proceedings are a tribute to the founder of the Center, Lawrence D. Longo, M.D. These chapters present contributions from individuals who in some way or another were influenced by Dr. Longo. Covering a wide range of topics, and illustrating the diversity of thinking and scientific interests, these proceedings address basic science through to clinical problems in the developmental programming of health and disease"--Publisher's description.
    Also available: Print – 2014
  • 2012 Springer
    Engeser, Stefan.
  • 2006 Springer
    Hocking, Ailsa D.; Pitt, John I.; Samson, Robert A.; Thrane, U.
    Section 1. Understanding the fungi producing important mycotoxins -- Section 2. Media and method development in food mycology -- Section 3. Physiology and ecology of mycotoxigenic fungi -- Section 4. Control of fungi and mycotoxins in foods.
    Also available: Print – 2006
  • 2006 Springer
    Chang, J. W.; Katayama, Y.; Yamamoto, T.
    Also available: Print – 2006
  • 2009 Springer
    Valent, Barbara; Wang, Guo-Liang.
  • 2015 Springer
    Chang, Anne.
    This concise, easy-to-read book summarizes the current clinical evidence and basic science relating to aging and the skin, assisting the clinician in addressing skin problems in older dermatologic patients. Each chapter focuses on a particular area in which new knowledge has rapidly emerged over the past 5 years, ensuring that the book is completely up-to-date. Recent insights into aging skin from basic and translational science are first discussed, covering the underlying genetics and the potential role of topical agents and procedures in reversing the aging process. Evidence-based prescribing in older patients is then explained, and the evidence relating to treatments for psoriasis, reviewed. Further chapters in Geriatric Dermatology address non-surgical treatment options for basal cell carcinoma, the increase in and management of sexually transmitted diseases in older dermatology patients, and cutaneous signs of elder mistreatment. Case vignettes and informative illustrations assist the reader in quickly grasping the connection between an age-related process and its clinical impact. Geriatric Dermatology is written for dermatologists, research scientists with translational interest, geriatricians, and gerontologists.
    Also available: Print – 2015
  • 2006 Springer
    Spekowius, Gerhard; Wendler, Thomas.
  • 1977-
    Mason, Dean T.
    Status: Not Checked OutLane Catalog Record
  • 2012 Future Med
    Krum, Henry; Von Lueder, Thomas.
    Advances in heart failure management / Henry Krum & Thomas von Lueder -- Etiology and overview of heart failure / Yee Weng Wong & G. Michael Felker -- Pathophysiology and clinical manifestation / Thomas G. von Lueder & Dan Atar -- Imaging in heart failure / Sebastian Imre Sarvari & Thor Edvardsen -- Drug therapies for heart failure / Kaushik Guha & Theresa A. McDonagh -- Biomarkers in heart failure / Ashraf Mostafa, Mohamed El-Haddad & Jalal K. Ghali -- Atrial fibrillation in heart failure / Wanwarang Wongcharoen & Shih-Ann Chen -- Device therapy in heart failure / Evaldas Giedrimas & Bradley P. Knight -- Acute heart failure / Wolfgang Krûger -- Pediatric heart failure and adult congenital heart disease / Michael L. O'Byrne & Robert E. Shaddy -- Ventricular assist devices and heart transplantation / Jignesh Patel & Jaime D. Moriguchi -- Gene therapy / Henrike Tscheschner, Patrick Most & Philip Raake -- End-of-life care / Patricia M. Davidson & Phillip J. Newton -- Heart failure guidelines : translation into clinical practice / Nigel T. Lewis, Shanmugakumar Chinnappa, Gerald Partridge & Lip-Bun Tan.
  • 2013 Springer
    Freed, Eric O.
    Over the past decade, enormous progress has been made in understanding the late events in the HIV replication cycle. This has been made possible by major advances in cell biology, virology, and structural biology. The field continues to move forward rapidly, with important new discoveries being reported on a regular basis. The impact of this progress across a broad spectrum of biomedical research has been substantial. The increase in basic knowledge in the areas of HIV assembly, release, and maturation has been accompanied by new possibilities for therapeutic intervention.The work includes topics relating to basic molecular biology, cell biology, and structural biology of HIV assembly, coupled with more applied ideas of how this basic information can inform the field of antiretroviral research. The book covers all major topics pertaining to the late stages of HIV replication, with leaders in each area recruited to contribute chapters in their areas of expertise . The topics will be sufficiently focused to allow authors the opportunity to cover the latest developments in detail.
  • 2013 CRCnetBASE
    Duffy, Vincent G.
    "This book discusses how human factors and ergonomics principles can be applied to improve quality, safety, efficiency, and effectiveness in patient care. The topics will include the design of work environments to improve satisfaction and well-being of patients, healthcare providers, and professionals. The utility of this area of research is to aid the design of systems and devices for effective and safe healthcare delivery"-- Provided by publisher.
  • 2011 CRCnetBASE
    Duffy, Vincent G.
    "Based on recent research, this book discusses how to improve quality, safety, efficiency, and effectiveness in patient care through the application of human factors and ergonomics principles. It provides guidance for those involved with the design and application of systems and devices for effective and safe healthcare delivery from both a patient and staff perspective. Its huge range of chapters covers everything from the proper design of bed rails to the most efficient design of operating rooms, from the development of quality products to the rating of staff patient interaction. It considers ways to prevent elderly patient falls and ways to make best use of electronic health records. It covers staff interactions with patients as well as staff interaction with computers and medical devices. It also provides way to improve organizational aspects in a healthcare setting, and approaches to modeling and analysis specifically targeting those work aspects unique to healthcare. Explicitly, the book contains the following subject areas: I. Healthcare and Service Delivery. II. Patient Safety. III. Modeling and Analytical Approaches. IV. Human-System Interface: Computers & Medical Devices. V. Organizational Aspects"--Provided by publisher.
  • 2009 Am Chem Soc
    Bloomquist, Jeffrey R.; Clark, J. Marshall; Kawada, Hitoshi.
    Vector biology diagnostics and public health pesticides development through the product development partnership route / Janet Hemingway -- Pyrethroid resistance in the African malaria vector, Anopheles gambiae, and potential of alternative insecticides for indoor residual spraying and use on mosquito nets / Mark Rowland and Raphael N'Guessan -- Insecticide resistance in the mosquito Culex pipiens complex : concerns about development of pyrethroid resistance / Osamu Komagata, Shinji Kasai, and Takashi Tomita -- Vector control for prevention of dengue : current status and future strategies / Tessa B. Knox and Thomas W. Scott -- Current status and challenges of Chagas disease control initiatives in the Americas / Jun Nakagawa -- Human head lice : status, control, and resistance / J. Marshall Clark ... et al. -- ABC's of indoor health : allergens, baits, and cockroach mitigation strategies / Coby Schal -- Current status of house dust mites in Japan and prospects for control agents / Tomoyuki Hashimoto -- Controlling dengue virus transmission in the field with genetically modified mosquitoes / Ken E. Olson and Alexander W.E. Franz -- Pharmacological mapping of the acetylcholinesterase catalytic gorge in mosquitoes with bis(n)-tacrines / Troy D. Anderson ... et al. -- Olyset net : a long lasting insecticidal net for vector control / Takaaki Itoh ... [et al.] -- Biological efficacy of metofluthrin, a new pyrethroid insecticide, highly effective against mosquitoes / Takao Ishiwatari ... et al. -- An inconvenient truth of pyrethroids-do they have a promising future? / Hitoshi Kawada -- The body louse, Pediculus humanus humanus (Phthiraptera : Pediculidae), genome project : past, present, and opportunities for the futures / Barry R. Pittendrigh ... et al. -- Resistance management of the human head louse using molecular tools / Si Hyeock Lee ... et al. -- Monitoring of kdr-mediated pyrethroid resistance in head louse colonies in Japan / Shinji Kasai ... et al.
  • 2015 Springer
    Liao, Joseph; Su, Li-Ming.
    This book provides an overview of the current state-of-art in combining advances in biomedical imaging with intraoperative navigation and preoperative planning for urologic surgery. These advances hold great promise in improving diagnostic and therapeutic urologic interventions to improve patient outcomes. Leading experts in this exciting emerging field covers early clinical and pre-clinical applications of optical, ultrasound, cross-sectional, and computer-assisted imaging in urologic surgery. Advances in Image-Guided Urologic Surgery provides a unique and valuable resource for audience with clinical and research interest in minimally invasive surgery, endourology, urologic oncology, imaging, and biomedical engineering.
  • 2014 Springer
    Bellido Luque, Juan Antonio; Suarez Grau, Juan Manuel.
    With an increase in the use of laparoscopic techniques for the treatment of abdominal wall hernias, this comprehensive book provides a detailed description of the most up-to-date techniques used in the laparoscopic repair of inguinal and ventral incisional hernias. Advances in Laparoscopy of the Abdominal Wall Hernia takes the reader step-by-step through two laparoscopic techniques used in inguinal hernia correction: Extraperitoneal (TEP) and Transabdominal (TAPP), and guides the reader through the fundamentals of ventral hernia repair. The authors aim to show methods of dealing with rarer hernias and those of atypical location. This book will also inform the reader of the various kinds of meshes used and provides knowledge on how to fix them, as well as the advantages, disadvantages and indications of this type of prosthesis. Written by experts in the field, Advances in Laparoscopy of the Abdominal Wall Hernia is a valuable reference tool to surgeons and medical practitioners working in this field.
  • 2007 Springer
    Perner, Petra; Salvetti, Ovidio.
  • 2014 Springer
    Jeng, Bennie H.
    This book presents up-to-date information on the diagnosis and management of the spectrum of medical and surgical corneal diseases, with a special focus on new technology. The latest tools for diagnosing ocular surface disease, infectious keratitis, and ocular allergies are discussed, along with novel treatment options for these entities. The impact of progress in imaging and contact lens technology on the management of corneal conditions is fully described, and the efficacy of corneal collagen crosslinking for keratoconus and corneal ectasia is evaluated. Detailed attention is devoted to the latest surgical techniques, including lamellar keratoplasty, endothelial keratoplasty, keratoprosthesis, and laser-assisted penetrating keratoplasty. In addition, the role of the eye bank in facilitating corneal procedures is explained. Advances in Medical and Surgical Cornea is written by leading authorities who share a passion for effective, cutting-edge care. It will be invaluable for both experienced ophthalmologists and trainees.
  • v. 1-, 2011- Springer
  • 2007 Springer
    Buzug, Thorsten M.
  • 2016 Springer
    Donelli, Gianfranco.
    This Series will provide microbiologists, hygienists, epidemiologists and infectious diseases specialists with well-chosen contributed volumes containing updated information in the areas of basic and applied microbiology involving relevant issues for public health, including bacterial, fungal and parasitic infections, zoonoses and anthropozoonoses, environmental and food microbiology. The increasing threat of the multidrug-resistant microorganisms and the related host immune response, the new strategies for the treatment of biofilm-based, acute and chronic microbial infections, as well as the development of new vaccines and more efficacious antimicrobial drugs to prevent and treat human and animal infections will be also reviewed in this series in the light of the most recent achievements in these fields. Special attention will be devoted to the fast diffusion worldwide of the new findings of the most advanced translational researches carried out in the different fields of microbiological sciences, with the aim to promote a prompt validation and transfer at clinical level of the most promising experimental results.
  • 2011 Springer
    Alexandre, A.; Masini, Marcos; Menchetti, Pier Paolo Maria.
    Surgical anatomy of the sacral hiatus for caudal access to the spinal canal -- Radiologic anatomy of the sacral canal -- Imaging in degenerative spine pathology -- Operative management of lumbar disc herniation: the evolution of knowledge and surgical techniques in the last century -- Philosophy and concepts of modern spine surgery -- Minimally invasive treatment for refractory low back pain, targeted by epidural endoscopy with O2/O3 and steroid therapy -- Epidural injections: past, present and future -- Long term intrathecal infusion of opiates for treatment of failed back surgery syndrome -- Modic changes: anatomy, pathophysiology and clinical correlation -- Periduroscopy: general review of clinical features and development of operative models -- The effectiveness of endoscopic epidurolysis in treatment of degenerative chronic low back pain: a prospective analysis and follow-up at 48 months -- Endoscopic approaches to the spinal cord -- Application of pulsed radio frequency to the dorsal horn and dorsal roots -- Automated nucleotomy and nucleolysis with ozone -- Treatment of discogenic low back pain with intradiscal electrothermal therapy (IDET): 24 months follow-up in 50 consecutive patients -- Percutaneous coblation nucleoplasty in patients with contained lumbar disc prolapse: 1 year follow-up in a prospective case series -- Plasma-mediated disc decompression for contained cervical disc herniation: results through 5 years -- Percutaneous laser discectomy: experience and long term follow-up -- Mechanism of action of oxygen ozone therapy in the treatment of disc herniation and low back pain -- Treatment of symptomatic lumbar spinal degenerative pathologies by means of combined conservative biochemical treatments -- Oxygen-ozone therapy for degenerative spine disease in the elderly: a prospective study -- Ozone: the one and only drug -- Vertebral augmentation: 7 years experience -- Kyphoplasty in the treatment of osteoporotic vertebral compression fractures (VCF) procedure description and analysis of the outcomes of 128 patients -- Experience with coflex interspinous implant -- DIAM device for low back pain in degenerative disc disease: 24 months follow-up -- Percutaneous surgical treatment in lumbar spinal stenosis with Aperius-PercLID: indications, surgical technique and results -- Six level cervico-thoracic circumferential reconstruction: report of the second case of the literature -- Percutaneous vertebral augmentation: StabilitiT: a new delivery system for vertebral fractures -- Minimally invasive disc preserving surgery in cervical radiculopathies: the posterior microscopic and endoscopic approach -- The fullendoscopic anterior cervical fusion: a new horizon for selective percutaneous endoscopic cervical decompression -- Leucocyte-platelet haemocomponents for topical use: regenerative potentiality -- Current surgical options for articular cartilage repair -- Facial-hypoglossal nerve end-to-side neurorrhaphy: anatomical study in rats -- Anatomic study in cadaver of the motor branch of the musculocutaneous nerve -- Exposure of the sciatic nerve in the gluteal region without sectioning the gluteus maximus: an anatomical and microsurgical study -- Experimental and clinical employment of end-to-side coaptation: our experience -- Considerations on the treatment of anterior interosseous nerve syndrome -- Percutaneous balloon compression of the gasserain ganglion for the treatment of trigeminal neuralgia: personal experience of 206 patients.
    Also available: Print – 2011
  • 2012 Springer
    Bottoni, Patrizia; Giardina, B.; Scatena, Roberto.
    Also available: Print – 2012
  • 2007 Springer
    Hasegawa, Paul M.; Jain, S. Mohan; Jenks, Matthew A.
  • 2007 Springer
    D'Adda di Fagagna, Febrizio.
    Genome instability, checkpoints, and the cell cycle. Comparison of DNA replication in Xenopus laevis and simian virus 40 / Maren Oehlmann, Cathal Mahon, and Heinz-Peter Nasheuer. A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors / P. Mathijs Voorhoeve ... [et al.] An investigation into 53BP1 complex formation / Kevin C. Roche and Noel F. Lowndes. Short abstracts--session I -- Tumor and microenvironment interactions. Tumor promotion by tumor-associated macrophages / Chiara Porta ... [et al.] The AP-2[alpha] transcription factor regulates tumor cell migration and apoptosis / Francesca Orso ... [et al.] Modulatory actions of neuropeptide Y on prostate cancer growth: role of MAP kinase/ERK 1/2 activation / Massimiliano Ruscica ... [et al.] Short abstracts--session II -- Animal models. The Arf tumor suppressor in acute leukemias: insights from mouse models of Bcr-Abl-induced acute lymphoblastic leukemia / Richard T. Williams and Charles J. Sherr. Short abstracts--session III -- Transcription and epigenetics. Short abstracts--session IV -- High-throughput approaches and imaging. Identification and validation of the anaplastic large cell lymphoma signature / Roberto Piva, Elisa Pellegrino, and Giorgio Inghirami. Cell-cycle inhibitor profiling by high-content analysis / Fabio Gasparri, Antonella Ciavolella, and Arturo Galvani. Short abstracts-session V -- Novel pathways and therapeutic targets. Regulation for nuclear targeting of the Abl tyrosine kinase in response to DNA damage / Kiyotsugu Yoshida. Short abstracts--session VI -- Poster abstracts.
    Also available: Print – 2007
  • 2013 Future Med
    Ottervanger, Jan Paul.
    The different faces of myocardial infarction / Jan Paul Ottervanger -- Epidemiology and classification of myocardial infarction / Michael Connolly & Ian Menown -- Risk factors for prognosis and secondary prevention of myocardial infarction / Daisaku Nakatani & Masatsugu Hori -- Pathophysiology of acute myocardial infarction / Panagiota Christia & Nikolaos G. Frangogiannis -- Symptoms and diagnosis of myocardial infarction/ Amber Marie Otten & Jan Paul Ottervanger -- Myocardial infarction imaging / Jagadeesh K. Kalavakunta, Imad Ahmado, Oliver G. Abela & George S. Abela -- Emergency management of ST-elevation myocardial infarction / Elliott Elias, Piera Capranzano & George Dangas -- Long-term care and prevention / Rebecca F. Rosenwasser, Katie Anderson & Benjamin J. Epstein -- Prognosis following myocardial infarction / Brandon K. Itagaki & Somjot S. Brar -- Future directions in the treatment of myocardial infarction / Jerome Roncalli -- Index.
  • 2013 CRCnetBASE
    Scholey, Andrew; Stough, Con.
    Pt. 1. Methodologies to measure cognition in natural medicine trials -- pt. 2. Vitamins and nutrients -- pt. 3. Essential fatty acids and neurocognition -- pt. 4. Herbal medicines, nutraceuticals and neurocognition.
  • 2006 Springer
    Baudry, M.; Taketani, Makoto.
    Also available: Print – 2006
  • 2011 Future Med
    Öberg, Kjell.
    Advances in neuroendocrine tumor management / Kjell Öberg -- Classification of digestive neuroendocrine neoplasm / Guido Rindi & Frediano Inzani -- Molecular profile and diagnosis / Christos Toumpanakis -- Surgical approach / Rossella Bettini & Massimo Falconi -- Somatostatin analogs / Wouter W. de Herder -- Combinational chemotherapy and radiotherapy / Emilio Bajetta, Emilio Bombardieri, Laura Catena, Monica Valente & Nadia Bianco -- Which therapy for which patient? / Kjell Öberg.
  • 2012 Springer
    Kozma, Robert; Pazienza, Giovanni E.; Pino, Robinson E.
    Physical implementation of the memristor at industrial scale sparked the interest from various disciplines, ranging from physics, nanotechnology, electrical engineering, neuroscience, to intelligent robotics. As any promising new technology, it has raised hopes and questions; it is an extremely challenging task to live up to the high expectations and to devise revolutionary and feasible future applications for memristive devices. The possibility of gathering prominent scientists in the heart of the Silicon Valley given by the 2011 International Joint Conference on Neural Networks held in San Jose, CA, has offered us the unique opportunity of organizing a series of special events on the present status and future perspectives in neuromorphic memristor science. This book presents a selection of the remarkable contributions given by the leaders of the field and it may serve as inspiration and future reference to all researchers that want to explore the extraordinary possibilities given by this revolutionary concept.
  • 2011 Springer
    Adams, Niall M.; Freemont, Paul S.
  • 2014 Springer
    Zappia, Vincenzo.
    This book comprises proceedings from the Third International Conference on Advances in Nutrition and Cancer, held in Naples in May 2012. This highly multidisciplinary meeting analyzed nutrition and cancer from different perspectives and on the basis of distinct and up-to-date experimental approaches. Knowledge on the relation between lifestyle, diet, and cancer is explored in a number of contributions, and the role of dietary intervention in cancer patients is discussed. Issues of vital interest to the research community, such as epidemiological and experimental oncology (genetics, epigenetics, and the mechanisms of action of natural compounds in the diet), receive detailed consideration. A further key topic is the emerging molecular technologies (the -omics) that can cast light on the interplay between nutrition and human malignancies. Chapters take the form of reviews that include sections presenting expert opinions. Advances in Nutrition and Cancer will be an invaluable source of topical information for all researchers and clinicians with an interest in this field.
    Also available: Print – 2014
  • 2012 Future Med
    Schwartz, Peter E.
    Advances in ovarian cancer management / Peter E. Schwartz -- Etiology and overview / Gang Ye, Stefanie Bernaudo & Chun Peng -- Diagnostic imaging in the management of ovarian masses / Amit Mahajan, Indukala Doddamane & Shirley McCarthy -- Initial surgical management of ovarian cancer / Jason Knight & Peter G. Rose -- Initial chemotherapy for the treatment of ovarian cancer / Katherine M. Moxley & Robert S. Mannel -- Neoadjuvant chemotherapy in the management of advanced ovarian cancer / Peter E. Schwartz -- Intraperitoneal chemotherapy : its use in epithelial ovarian cancer / Neesha Dhani & Helen Mackay -- Chemotherapeutic management of recurrent ovarian cancer / Marcia Hall -- Emerging chemotherapy agents in ovarian cancer / Daliah Tsoref & Amit M. Oza -- Surgical management of recurrent ovarian cancer / Eelco de Bree -- Angiogenesis in ovarian cancer / Vincent Castonguay & Amit M. Oza -- Antigen-specific immunotherapy for ovarian cancer / Dana M. Roque & Alessandro D. Santin -- Poly(ADP-ribose) polymerase inhibitors and epithelial ovarian cancer -- Thomas P. McNally, Gillianne G.Y. Lai & Richard T. Penson -- Emerging targeted therapies / Mirko Marabese & Massimo Broggini -- Palliative care in ovarian cancer / Cynthia O'Sullivan, Elizabeth Ercolano & Ruth McCorkle -- Guidelines in ovarian cancer / Domenica Lorusso, Antonella Pietragalla & Giovanni Scambia -- Index.
  • 2011 Future Med
    Friess, Helmut; Hüser, Norbert.
    Advances in pancreatic cancer treatment / Helmut Friess & Norbert Hüser -- Pathophysiology of pancreatic cancer / J. Matthias Löhr, Stephan L. Haas & Rainer Heuchel -- Molecular diagnostics in pancreatic cancer / David K. Chang, Sean M. Grimmond & Andrew V. Biankin -- Surgical therapy for pancreatic cancer / Norbert Hüser, Volker Assfalg & Helmut Friess -- Multimodal treatment concepts in pancreatic cancer / Daniel Reim, Alexander Novotny & Helmut Friess -- Consensus guidelines in pancreatic cancer treatment / Wasif Saif -- Drugs in clinical trials & future directions / Zhiqiang Huang & Donald J. Buchsbaum.
  • 2011 Future Med
    Friedman, Joseph H.
    Advances in Parkinson's disease management / Joseph H. Friedman -- Etiology and overview / Witold Polanski -- Biomarkers of Parkinson's disease / Mauro Fasano & Tiziana Alberio -- Imaging Parkinson's disease / David J. Brooks -- Dopaminergic agents / Lawrence W. Elmer & Robert A. Hauser -- Combined dopaminergic and nondopaminergic therapies / Mary Ann Thenganatt & Cheryl H. Waters -- Future drug therapy / Makoto Naoi & Wakako Maruyama -- Drug therapies for neuropsychiatric and autonomic disturbances in patients with PD / Thomas Müller -- Surgical treatment for Parkinson's disease / Sumito Sato & Hideki Mochizuki -- Cell and gene transplantation for Parkinson's disease : from the clinic / Paul E. Greene -- Current evidence-based guidelines for the management of Parkinson's disease / Nicolas Phielipp & Janis Miyasaki -- Index.
  • v. 1, 1979.
    Guilleminault, Christian; Korobkin, Rowena.
    Status: Not Checked OutLane Catalog Record
  • 2007 Springer
    González-Moreno, S.
    Management of Peritoneal Surface Malignancy: A Short History / Paul H. Sugarbaker -- The Natural History of Free Cancer Cells in the Peritoneal Cavity / Yutaka Yonemura, Taiichi Kawamura, Etsurou Bandou, Gorou Tsukiyama and Yoshio Endou, et al. -- Pathological Evaluation and Implications of Serosal Involvement in Gastrointestinal Cancer / Linmarie Ludeman and Neil A. Shepherd -- Principles of Perioperative Intraperitoneal Chemotherapy for Peritoneal Carcinomatosis / Eelco de Bree and Dimitris D. Tsiftsis -- Experimental and Pharmacokinetic Studies in Intraperitoneal Chemotherapy: From Laboratory Bench to Bedside / Eelco de Bree and Dimitris D. Tsiftsis -- Technology for the Delivery of Hyperthermic Intraoperative Intraperitoneal Chemotherapy: A Survey of Techniques / Amod A. Sarnaik, Jeffrey J. Sussman, Syed A. Ahmad, Benjamin C. McIntyre and Andrew M. Lowy -- Adjuvant Intraperitoneal Chemotherapy: A Review / Paul H. Sugarbaker -- Clinical Research Methodology in Peritoneal Surface Oncology: A Difficult Challenge / François-Noël Gilly, Olivier Glehen, Annie C. Beaujard and Eddy Cotte -- Lessons Learnt from Clinical Trials in Peritoneal Surface Oncology: Colorectal Carcinomatosis / Frans A. N. Zoetmulder and Vic J. Verwaa -- Experimental Models and Questions in Basic Science Research for Pseudomyxoma Peritonei / Laura A. Lambert, Donald H. Lambert and Paul Mansfield -- Peritoneal Carcinomatosis of Colorectal Origin: Recent Advances and Future Evolution Toward a Curative Treatment / Dominique Elias and Diane Goere -- Pathologic Characterization and Differential Diagnosis of Malignant Peritoneal Mesothelioma / Nelson G. Ordóñez -- Advances in Clinical Research and Management of Diffuse Peritoneal Mesothelioma / Marcello Deraco, Dario Baratti, Nadia Zaffaroni, Antonello Domenico Cabras and Shigeki Kusamura -- Advances in the Management of Gastric Cancer with Peritoneal Dissemination / Yutaka Yonemura, Taiichi Kawamura, Etsurou Bandou, Gorou Tsukiyama and Masayuki Nemoto, et al. -- Intraperitoneal Chemotherapy in the Management of Ovarian Cancer / Maurie Markman.
    Also available: Print – 2007
  • 2011 Future Med
    Roukos, Dimitrios H.
    Personalized genomic medicine: is a cancer care revolution achievable? / Dimitrios H. Roukos -- Targeting the individual cancer patient / Georgios Baltogiannis, Christos S. Katsios & Dimitrios H. Roukos -- Biomarkers-guided targeted drugs: new clinical trials design and practice necessity / Ming-Wen An, Sumithra J. Mandrekar & Daniel J. Sargent -- Personalized management for breast cancer / George C. Zografos, Dimosthenis T. Chrysikos, Paraskevi Liakou & Flora Zagouri -- Personalized management for non-small-cell lung cancer / Martin Früh, Florent Baty, Lukas Kern, Martin P. Putora & Martin Brutsche -- Personalized management for colorectal cancer / Ana Custodio & Jaime Feliu -- Successes, challenges and future directions / Stephen J. Clarke.
  • 2011 Future Med
    Saijō, Nagahiro.
    Advances in personalized therapy for lung cancer / Nagahiro Saijo -- Biomarkers in lung cancer / Tobenna Nwizu & Ravi Salgia -- EGF receptor-targeted drugs / Tetsuya Mitsudomi -- Antiangiogenic therapies for non-small-cell lung cancer / Suresh S. Ramalingam & Chandra P. Belani -- DNA-targeted drugs / Judith Meza-Junco & Michael B. Sawyer.
  • 2007 Springer
    Xu, Fangsen.
  • v. 1-, 2012- Springer
    Golubnitschaja, Olga.
  • 2007 Springer
    Gámez, José A.; Lucas, Peter; Salmerón, Antonio.
  • 2014 Springer
    Lebwohl, Mark G.; Weinberg, J. M.
    The understanding and management of psoriasis have evolved dramatically over the last decades and, as a result, guidelines and treatment options have changed dramatically. To meet the need for a up-to-date practical resource in this area, the Editors have brought together a team of experts in the field to produce a highly informative and illustrated guide to the decision-making process for psoriasis. Advances in Psoriasis: A Multisystemic Guide provides physicians with a reference on the disease and its comorbidities and therapeutic options. It will help physicians further their knowledge of the science and therapy of psoriasis. As well as practicing dermatologists, fellows in dermatology will find this book to be an essential training resource to learn about the treatment and management of psoriasis.
  • 2013 Future Med
    Öberg, Kjell.
    Advances in pulmonary neuroendocrine tumor management / Kjell Öberg -- Classification / Mauro Papotti -- Molecular imaging & peptide receptor radionuclide therapy / Richard P. Baum, Harshad R. Kulkarni & Dieter Hörsch -- Biotherapy : somatostatin analogs and IFN-[alpha] / Dan Granberg -- Typical and atypical bronchial carcinoid tumors / Michael Beckles, Dalvinder Mandair, Christos Toumpanakis & Martyn Caplin -- Small-cell lung cancer and large-cell neuroendocrine tumors of the lung / David Planchard & Eric Baudin -- Thymic neuroendocrine tumors / Piero Ferolla -- Algorithm for management of bronchopulmonary neuroendocrine tumors / Kjell Öberg -- Index.
  • 2011 Springer
    Brady, Luther W.; Jeremić, Branislav.
  • 2012 Springer
    Castoria, Gabriella; Migliaccio, Antimo.
    [1.] Non-genomic Action of Steroid Hormones: More Questions than Answers / Antimo Migliaccio, Gabriella Castoria, Antonio Bilancio, Pia Giovannelli, Marzia Di Donato and Ferdinando Auricchio -- Part I. Breast Cancer -- [2.] Progesterone Signaling to Chromatin in Breast Cancer Cells. Two Initial Cycles of Remodeling / Guillermo P. Vicent, Roser Zaurin, Cecilia Ballaré, A. Silvina Nacht, Roni H. G. Wright, Francois Le Dily, Giancarlo Castellano, Jofre Font-Mateu and Miguel Beato -- [3.] Cooperative Interactions Between c-Src, Estrogen Receptors and Receptor Tyrosine Kinases in Breast Cancer / Sarah J. Parsons, Jessica E. Pritchard, Emily M. Fox and Margaret A. Shupnik -- [4.] Cross Talk Between ER[alpha] and Src Signaling and Its Relevance to ER Status and Hormone Responsiveness / Jun Sun, Wen Zhou, Zafar Nawaz and Joyce M. Slingerland -- [5.] Post-translational Modifications of ER Alpha in Rapid Estrogen's Action / Muriel Le Romancer, Coralie Poulard, Stéphanie Sentis, and Laura Corbo -- [6.] Sex-Steroid Rapid Action and Its Role in Invasiveness and Metastasis of Breast Cancer / Marina Ines Flamini, Angel Matias Sanchez, Xiao-Dong Fu and Tommaso Simoncini -- [7.] Unraveling the Role of GPER in Breast Cancer / Rosamaria Lappano and Marcello Maggiolini -- [8.] Nongenomic Actions of Estrogens and Xenoestrogens Affecting Endocrine Cancer Cells / Cheryl S. Watson, Dragoslava Zivadinovic, Yow-Jiun Jeng, Rebecca A. Alyea, Terumi Midoro-Horiuti, Randall Goldblum and Anannya Banga -- Part II. Prostate Cancer -- [9.] Differential Functions of Stromal and Epithelial Androgen Receptor in Prostate Cancer Before and After Castration Resistant Stage / S. Lee, K.-P. Lai, S. Yeh and C. Chang -- [10.] Role of Androgens and Androgen Receptor in Prostate Cancer: Genomic and Non-Genomic Actions / Sara Marchiani, Lara Tamburrino, Monica Muratori, Lorella Bonaccorsi, Gianni Forti and Elisabetta Baldi -- [11.] Mechanisms of Signal Transduction in Prostate Cancer: The Role of PI3-Kinase Pathway in Androgen Action / Laurent Morel and Silvère Baron -- [12.] The IGF-I Axis in Prostate Cancer: The Role of Rapid Steroid Actions / Antonino Belfiore -- Androgen Receptor Pathway in Prostate Cancer: Old Target and New Drugs / Christophe Massard and Karim Fizazi -- Part III. New Tools for Steroid Receptor Analysis and Regulatory Networks -- [13.] Quantitative Visualization of Sex Steroid Receptor Functions: AR and ER[alpha] / Michael J. Bolt, Sean M. Hartig, Adam T. Szafran, Sanjay N. Mediwala, Marco Marcelli and Michael A. Mancini -- [14.] Micropatterned Surfaces as Tools for the Study of the Rapid Non-genomic Actions of Steroid Receptors / Andrew C. B. Cato, Emmanuel Oppong and Sylwia Sekula-Neuner.
  • 2007 Ovid
    Kovac, S. Robert; Zimmerman, Carl W.
  • 2010 Springer
    Altankov, George; Lendlein, Andreas; Shastri, V. Prasad.
    Cell Adhesions and Signaling: A Tool for Biocompatibility Assessment / Roumen Pankov and Albena Momchilova -- Development of Provisional Extracellular Matrix on Biomaterials Interface: Lessons from In Vitro Cell Culture / George Altankov, Thomas Groth, Elisabeth Engel, Jonas Gustavsson and Marta Pegueroles, et al. -- Endothelial Progenitor Cells for Tissue Engineering and Tissue Regeneration Endothelial Progenitor Cells / Joyce Bischoff -- Dermal Precursors and the Origins of the Wound Fibroblast / Jeffrey M. Davidson -- Cell Based Therapies: What Do We Learn from Periosteal Osteochondrogenesis? / Peter J. Emans, Tim J. M. Welting and Venkatram Prasad Shastri -- Bioreactor Systems in Regenerative Medicine / Ivan Martin, Stefania A. Riboldi and David Wendt -- Biomimetic Approaches to Design of Tissue Engineering Bioreactors / Bojana Obradovic, Milica Radisic and Gordana Vunjak-Novakovic -- The Nature of the Thermal Transition Influences the Shape-Memory Behavior of Polymer Networks / Andreas Lendlein, Marc Behl and Stefan Kamlage -- Nanoengineered Systems for Regenerative Medicine Surface Engineered Polymeric Biomaterials with Improved Bio-Contact Properties / Todorka Vladkova and Natalia Krasteva -- Nanocomposites for Regenerative Medicine / Ryan Hoshi, Antonio R. Webb, Hongjin Qiu and Guillermo A. Ameer -- Role of Spatial Distribution of Matricellular Cues in Controlling Cell Functions / Daniela Guarnieri and Paolo A. Netti -- Materials Surface Effects on Biological Interactions / Josep A. Planell, Melba Navarro, George Altankov, Conrado Aparicio and Elisabeth Engel, et al. -- Chemical and Physical Modifications of Biomaterial Surfaces to Control Adhesion of Cells / Thomas Groth, Zhen-Mei Liu, Marcus Niepel, Dieter Peschel and Kristin Kirchhof, et al. -- Results of Biocompatibility Testing of Novel, Multifunctional Polymeric Implant Materials In-Vitro and In-Vivo / Dorothee Rickert, Rosemarie Fuhrmann, Bernhard Hiebl, Andreas Lendlein and Ralf-Peter Franke -- UFOs, Worms, and Surfboards: What Shapes Teach Us About Cell-Material Interactions / Julie A. Champion and Samir Mitragotri -- Nano-engineered Thin Films for Cell and Tissue-Contacting Applications / Richard F. Haglund -- Injectable Hydrogels: From Basics to Nanotechnological Features and Potential Advances / Biancamaria Baroli -- Polyelectrolyte Complexes as Smart Nanoengineered Systems for Biotechnology and Gene Delivery / Vladimir A. Izumrudov.
  • 2015 Springer
    Streckfus, Charles F.
    This book reviews the progress made in salivary diagnostics and identifies the likely direction of future endeavors. After an introductory section describing the histological and anatomical features of the salivary glands and salivary function, salivary collection devices and diagnostic platforms are reviewed. The field of ℓ́ℓsalivaomicsℓ́ℓ is then considered in detail, covering, for example, proteomics, the peptidome, DNA and RNA analysis, biomarkers, and methods for biomarker discovery. Salivary diagnostics for oral and systemic diseases are thoroughly discussed, and the role of salivary gland tissue engineering for future diagnostics is explored. The book closes by considering legal issues and barriers to salivary diagnostic development. Advances in Salivary Diagnostics will be an informative and stimulating reference for both practitioners and students.
  • 2010 Springer
    Busatto, Geraldo; Gattaz, W.-F.
  • 2012 Karger
    Rudolph, K. Lenhard.
    Speakers at the symposium / Morita, M. -- Aging of the niche and the microenvironment and its role in stem cell aging / Geiger, H. -- Hematopoietic stem cell aging and cancer / Chen, Y., Ju, Z. -- DNA damage, checkpoint responses, and cell cycle control in aging stem cells / Kleinhans, K.N., Burkhalter, M.D. -- Hematopoietic stem cell aging and fate decision / Illing, A., Morita, Y. -- Stem cell therapy and stress response in pancreas and intestine -- Sperka, T., Omrani, O. -- Niche-stem cell interations and environmental influences / Tang, D. -- Stem cells and metabolism / Missios, P., Guachalla, L. -- Molecular mechanisms of muscle stem cell aging / Baig, A.H., Tümpel, S. -- Neural stem cells in development and aging / Schmidt-Strassburger, U.
  • 2012 Springer
    Aghdami, Nasser; Baharvand, Hossein.
    Advances in stem cell research discusses recent advances in stem cell science, including therapeutic applications. This volume covers such topics as biomanufacturing iPS cells for therapeutic applications, techniques for controlling stem cell fate decisions, as well as current basic research in such areas as germ line stem cells, genomics and proteomics in stem cell research. It is a useful book for biology and clinical scientists, especially young investigators and stem cell biology students who are newly entering the world of stem cells research. The editors hope that the new knowledge and research outlined in this book will help contribute to new therapies for a wide variety of diseases that presently afflict humanity.
  • 2012 Springer
    Goryachev, Andrew B.; Goryanin, Igor I.
    Part 1. Multiscale biological networks: identification, modeling and analysis -- Modular Analysis of Biological Networks / Hans-Michael Kaltenbach and Jörg Stelling -- Modeling Signaling Networks Using High-throughput Phospho-proteomics / Camille Terfve and Julio Saez-Rodriguez -- An Integrated Bayesian Framework for Identifying Phosphorylation Networks in Stimulated Cells / Tapesh Santra, Boris Kholodenko and Walter Kolch -- Signaling Cascades: Consequences of Varying Substrate and Phosphatase Levels / Elisenda Feliu, Michael Knudsen and Carsten Wiuf -- Heterogeneous Biological Network Visualization System: Case Study in Context of Medical Image Data / Erno Lindfors, Jussi Mattila, Peddinti V. Gopalacharyulu, Antti Pesonen and Jyrki Lötjönen, et al. -- Evolution of the Cognitive Proteome: From Static to Dynamic Network Models / J. Douglas Armstrong and Oksana Sorokina -- Molecular Systems Biology of Sic1 in Yeast Cell Cycle Regulation Through Multiscale Modeling / Matteo Barberis -- Proteome-Wide Screens in Saccharomyces cerevisiae Using the Yeast GFP Collection / Yolanda T. Chong, Michael J. Cox and Brenda Andrews -- Unraveling the Complex Regulatory Relationships Between Metabolism and Signal Transduction in Cancer / Michelle L. Wynn, Sofia D. Merajver and Santiago Schnell -- Part 2. Cellular decision making: adaptation, differentiation and death -- The Cell as a Thermostat: How Much does it Know? / Dennis Bray -- Stem Cell Differentiation as a Renewal-Reward Process: Predictions and Validation in the Colonic Crypt / Kiran Gireesan Vanaja, Andrew P. Feinberg and Andre Levchenko -- A Dynamic Physical Model of Cell Migration, Differentiation and Apoptosis in Caenorhabditis elegans / Antje Beyer, Ralf Eberhard, Nir Piterman, Michael O. Hengartner and Alex Hajnal, et al. -- A Modular Model of the Apoptosis Machinery / E. O. Kutumova, I. N. Kiselev, R. N. Sharipov, I. N. Lavrik and Fedor A. Kolpakov -- An Ensemble Approach for Inferring Semi-quantitative Regulatory Dynamics for the Differentiation of Mouse Embryonic Stem Cells Using Prior Knowledge / Dominik Lutter, Philipp Bruns and Fabian J. Theis -- Cell Death and Life in Cancer: Mathematical Modeling of Cell Fate Decisions / Andrei Zinovyev, Simon Fourquet, Laurent Tournier, Laurence Calzone and Emmanuel Barillot -- Theoretical Aspects of Cellular Decision-Making and Information-Processing / Tetsuya J. Kobayashi and Atsushi Kamimura -- Zooming in on Yeast Osmoadaptation / Clemens Kühn and Edda Klipp -- Part 3. Spatial and temporal dymensions of intracellular dynamics -- Receptor Dynamics in Signaling / Verena Becker, Jens Timmer and Ursula Klingmüller -- A Systems-Biology Approach to Yeast Actin Cables / Tyler Drake, Eddy Yusuf and Dimitrios Vavylonis -- Modeling Morphodynamic Phenotypes and Dynamic Regimes of Cell Motion / Mihaela Enculescu and Martin Falcke -- Time-Structure of the Yeast Metabolism In vivo / Kalesh Sasidharan, Masaru Tomita, Miguel Aon, David Lloyd and Douglas B. Murray -- Coarse Graining Escherichia coli Chemotaxis: From Multi-flagella Propulsion to Logarithmic Sensing / Tine Curk, Franziska Matthäus, Yifat Brill-Karniely and Jure Dobnikar -- Self-Feedback in Actin Polymerization / Anders E. Carlsson -- Part 4. Computational tools, algorithms and theoretical methods for systems biology -- Global Optimization in Systems Biology: Stochastic Methods and Their Applications / Eva Balsa-Canto, J. R. Banga, J. A. Egea, A. Fernandez-Villaverde and G. M. de Hijas-Liste -- Mathematical Modeling of the Human Energy Metabolism Based on the Selfish Brain Theory / Matthias Chung and Britta Göbel -- Identification of Sensitive Enzymes in the Photosynthetic Carbon Metabolism / Renato Umeton, Giovanni Stracquadanio, Alessio Papini, Jole Costanza and Pietro Liò, et al. -- Formal Methods for Checking the Consistency of Biological Models / Allan Clark, Vashti Galpin, Stephen Gilmore, Maria Luisa Guerriero and Jane Hillston -- Global Parameter Identification of Stochastic Reaction Networks from Single Trajectories / Christian L. Müller, Rajesh Ramaswamy and Ivo F. Sbalzarini -- A Systems Biology View of Adaptation in Sensory Mechanisms / Pablo A. Iglesias -- Leveraging Modeling Approaches: Reaction Networks and Rules / Michael L. Blinov and Ion I. Moraru -- Part 5. Applications of systems biology in medicine, biotechnology and pharmaceutical industry -- Why and How to Expand the Role of Systems Biology in Pharmaceutical Research and Development / Robert D. Phair -- Multiscale Mechanistic Modeling in Pharmaceutical Research and Development / Lars Kuepfer, Jörg Lippert and Thomas Eissing -- Re-analysis of Bipolar Disorder and Schizophrenia Gene Expression Complements the Kraepelinian Dichotomy / Kui Qian, Antonio Di Lieto, Jukka Corander, Petri Auvinen and Dario Greco -- Bringing Together Models from Bottom-Up and Top-Down Approaches: An Application for Growth of Escherichia coli on Different Carbohydrates / Andeas Kremling -- A Differential Equation Model to Investigate the Dynamics of the Bovine Estrous Cycle / H. M. T. Boer, C. Stötzel, S. Röblitz and H. Woelders -- Reducing Systems Biology to Practice in Pharmaceutical Company Research; Selected Case Studies / N. Benson, L. Cucurull-Sanchez, O. Demin, S. Smirnov and P. van der Graaf -- System-Scale Network Modeling of Cancer Using EPoC / Tobias Abenius, Rebecka Jörnsten, Teresia Kling, Linnéa Schmidt and José Sánchez, et al. -- Early Patient Stratification and Predictive Biomarkers in Drug Discovery and Development / Daphna Laifenfeld, David A. Drubin, Natalie L. Catlett, Jennifer S. Park and Aaron A. Van Hooser, et al. -- Biomedical Atlases: Systematics, Informatics and Analysis / Richard A. Baldock and Albert Burger.
    Also available: Print – 2012
  • 2013 Future Med
    Fraidenburg, Dustin R.; Smith, Kimberly A.; Yuan, Jason X.-J.
    Current therapies for the treatment of pulmonary arterial hypertension / Kimberly A. Smith, Dustin R. Fraidenburg & Jason X.-J. Yuan -- Etiology and prevalence of pulmonary arterial hypertension / Catharina Belge & Marion Delcroix -- Pathology and diagnosis of pulmonary arterial hypertension / Carlyne D. Cool -- Conventional therapy / Stefania Cicalini & Nicola Petrosillo -- Targeted therapies : prostaglandins / Benton Ashlock & David Poch -- Targeted therapies : endothelin receptor antagonists / Kimberly A. Smith, Dustin R. Fraidenburg & Jason X.-J. Yuan -- Stimulators and activators of soluble guanylate cyclase : potential therapeutic indications / Bobby D. Nossaman, George F. Lasker, Edward A. Pankey, Raj D. Parikh & Philip J. Kadowitz -- Surgical approaches in pulmonary arterial hypertension / Vaidehi Kaza, Jodie Moore, Srinivas Bollineni & Fernando Torres -- Monitoring and prognosis of pulmonary arterial hypertension / Melanie J. Brewis & Andrew J. Peacock -- Right ventricular failure / Raj Parikh & Philip J. Kadowitz -- Index.
  • 2009. Karger
    Jones, T. Hugh.
    Current guidelines for the diagnosis of testosterone deficiency / S. Arver, M. Lehtihet -- Laboratory measurement of testosterone / M.J. Diver -- Advances in testosterone replacement therapy / L.J.G. Gooren -- The role of the CAG repeat androgen receptor polymorphism in andrology / M. Zitzmann -- Late-onset hypogonadism / L.J.G Gooren -- Testosterone in obesity, metabolic syndrome, and type 2 diabetes / R.D. Stanworth, T.H. Jones -- Testosterone and coronary artery disease / J.E. Nettleship ... [et al.] -- Erectile dysfunction and testosterone deficiency / M. Blute ... [et al.] -- Testosterone, bone, and osteoporosis / S.P. Tuck, R.M. Francis -- Frailty and muscle function : role for testosterone? / U. Srinivas-Shankar, F.C.W. Wu -- Testosterone effects on cognition in health and disease / M.M. Cherrier -- Anabolic applications of androgens for functional limitations associated with aging and chronic illness / S. Bhasin, T.W. Storer -- Testosterone in chronic heart failure / C.J. Malkin, T.H. Jones, K.S. Channer -- Testosterone and prostate safety / A. Morgentaler, C. Schulman.
  • 2011 Future Med
    Hudis, Clifford A.; Traina, Tiffany A.
    Advances in the management of triple-negative breast cancer / Tiffany A. Traina & Clifford A. Hudis -- Etiology and risk factors / Laura Fejerman & Elad Ziv -- Diagnosis and pathology / Govardhanan Nagaiah & Jame Abraham -- Molecular subtypes and emerging therapeutic opportunities / Anastasia Constantinidou, Robin L. Jones & Jorge S. Reis-Filho -- Molecular profile of triple-negative breast cancer / Leonel F. Hernandez-Aya & Ana Maria Gonzalez-Angulo -- Role of metabolic rehabilitation-based approach in TNBC : biguanide metformin and more / Lev M. Berstein, Garik A. Dashyan & Vladimir F. Semiglazov -- Poly(ADP-ribose) polymerase inhibitors in triple-negative breast cancer / Mark Robson -- Targeted therapies: EGFR inhibitors / Farrah M. Datko & Maura N. Dickler -- Targeted therapies : other agents in clinical trials / Brian R. Haney, Nathan M. Shumway & George E. Peoples -- Combined therapies and future directions / Anastasia Pazaiti & Ian S. Fentiman.
  • 2010 CRCnetBASE
    Koob, George F.; Kuhn, Cynthia.
    Advances in animal models of relapse for addiction research / Friedbert Weiss -- Application of chronic extracellular recording method to studies of cocaine self-administration : method and progress / Laura L. Peoples, Alexai V. Kravitz, and Karine Guillem -- Neurochemistry of addiction : monitoring essential neurotransmitters of addiction / Stefan G. Sandberg and Paul A. Garris -- Alcohol craving and relapse prediction : imaging studies / Andreas Heinz ... [et al.] -- Integrating behavioral and molecular approaches in mouse : self-administration studies / Danielle L. Graham and David W. Self -- Neuroeconomics : implications for understanding the neurobiology of addiction / Michael L. Platt ... [et al.].
  • 2012 Future Med
    Prados, Michael.
    Advances in the pathogenesis and treatment of glioblastoma multiforme / Michael Prados -- Pathogenesis, molecular characteristics and prognostic factors for survival / Keith L. Ligon -- Standard treatment approaches for newly diagnosed glioblastoma / Soon-Tae Lee & Patrick Y. Wen -- Targeted therapeutic strategies for relapsed disease / John F. de Groot & Howard Colman -- Genes, viruses, toxins and vaccines as therapeutic modalities / Tal Shahar, Manish K. Aghi & Zvi Ram -- Drug delivery strategies for glioblastoma / Pin-Yuan Chen, Dali Yin, John Forsayeth & Krystof S. Bankiewicz -- Index.
  • 2012 Future Med
    Keating, Michael J.; Tam, Constantine S.
    Advances in the treatment of B-cell chronic lymphocytic leukemia / Michael J. Keating & Constantine Tam -- Chronic lymphocytic leukemia : diagnosis and clinical staging / Stephen P. Mulligan & Constantine S. Tam -- Genetics in chronic lymphocytic leukemia / Stephan Stilgenbauer & Thorsten Zenz -- To treat or not to treat / Marco Montillo, Alessandra Tedeschi & Enrica Morra -- Chronic lymphocytic leukemia chemotherapy : two decades of progress / Carol Moreno & Emili Montserrat -- Stem cell transplantation / David G. Maloney -- Treatment options for refractory chronic lymphocytic leukemia / Marina Motta & Alessandra Ferrajoli -- Prognostic markers in chronic lymphocytic leukemia / Renata Walewska & David Oscier -- Therapeutic agents in development and future direction / Sarah Mougalian & Susan O'Brien -- Index.
  • 2013 Future Med
    Fava, Carmen; Saglio, Giuseppe Saglio.
    Advances in the treatment of chronic myeloid leukemia / Giuseppe Saglio & Carmen Fava -- Diagnosis and classification of the risk / Gabriele Gugliotta, Fausto Castagnetti, Francesca Palandri, Michele Baccarani & Gianantonio Rosti -- Genetics of chronic myeloid leukemia / Giovanna Rege-Cambrin, Emilia Giugliano & Patrizia Scaravaglio -- Molecular monitoring / Martin C. Müller, Christian Dietz & Benjamin Hanfstein -- Current targeted therapy with tyrosine kinase inhibitors / Massimo Breccia & Giuliana Alimena -- Stem cell transplantation and high-dose chemotherapy / Deena Iskander, Jane F. Apperley & Jirí Pavlu -- Treatment options for tyrosine kinase inhibitor-resistant chronic myeloid leukemia / Stephan Joseph Dorkhom, Hady Ghanem & Elias Jabbour -- Prognostic factors and future direction for chronic myeloid leukemia / David Marin & Antonia Rotolo -- Chronic myeloid leukemia : the possibility of a cure / Manuel Sobrinho-Simões, David M. Ross & Junia V. Melo -- Index.
  • 2011 Springer
    Feldmann, Marc; Kovalenko, Andrew; Wallach, David.
    Roles of the TNF family in tissue homeostasis and normal development -- Novel aspects of signaling activation by the TNF family: novel aspects of the functions of the TRAFs and cIAPs -- Novel aspects of signaling activation by the TNF: ubiquitin modification of signaling proteins -- Novel aspects of signaling activation by the TNF family: TNF signaling and gene regulatory networks -- Roles of the TNF family in infectious diseases and interrelationship of the TNF family and pattern recognition receptor signaling: roles of the TNF family in infectious diseases -- Roles of the TNF family in infectious diseases and interrelationship of the TNF family and pattern recognition receptor signaling: interrelationship of the TNF family and pattern recognition receptor signaling -- Novel aspects of immune regulation by the TNF family -- Control of lymphocyte function and repertoire by the TNF family -- Advances in applying our knowledge to therapy: mechanisms of pathological and therapeutic effects of the TNF family -- Advances in applying our knowledge to therapy: rational design of new means for therapeutic modulation of function of the TNF family -- Roles of the TNF family in neuronal development, function, and pathology -- Cell death mechanisms controlled by the TNF family -- Contributors to abstracts of talks and posters at the 12th TNF Conference -- Abstracts of talks and posters presented at the 12th TNF Conference.
    Also available: Print – 2011
  • 2007
    Dax, Elizabeth M.; Farrugia, Albert; Vyas, Girish N.
  • 2015 Springer
    Brown, Marc D.; Zwald, Fiona.
    This book provides an informative update on scientific advances relating to transplant dermatology that may be applicable to clinical practice. Commentary is provided on the emerging role of viruses in transplant dermatology, the management of skin disease secondary to transplant medication, sunscreen use in transplant recipients, the role of revision of immunosuppression, and advances in photodynamic therapy. The latest staging and management criteria for high-risk squamous cell carcinoma and the implications for clinical practice are then analyzed. Finally, the management of other cutaneous malignancies is discussed, covering malignant melanoma, Merkel cell carcinoma, and rarer tumors that also behave aggressively and require special consideration in solid organ transplant patients. Each particular advance is addressed in an individual chapter by leaders in the field. The book both expands current knowledge and complements previous textbooks on the subject.
  • 2014 Springer
    Rosenblatt, Joseph D.
    Recent advances in understanding of fundamental immunology have created new insights into the dynamic interactions between tumors and the immune system. This includes new understanding of T- and B-cell interaction, immune inhibitory mechanisms including the biology of T regulatory cells, myeloid suppressor cells, and dendritic cell subsets. Enhanced understanding of mechanisms underlying T-cell anergy such as arginine deprivation, immunosuppressive cytokines, defective innate and interferon response pathways, and NKG2D downregulation have all provided new insight into suppression of anti-tumors.
  • 2009 Springer
    Kazui, Teruhisa; Takamoto, Shinichi.
  • 2011 CRCnetBASE
    Karwowski, Waldemar; Marek, Tadeusz; Rice, Valerie J. Berg.
  • 2012 Springer
    Vreeland, Russell H.
    Approaches toward the study of halophilic microorganisms in their natural environments : who are they and what are they doing? / Aharon Oren -- Media and conditions for the growth of halophilic and halolerant bacteria and ardchaea / Mark A. Schneegurt -- Taxonomy of halophilic archaea and bacteria / Antonio Ventosa ... [et al.] -- Halophilic viruses / Shereen Sabet -- Microorganisms in evaporites : review of modern geomicrobiology / Tim K. Lowenstein -- Searching for microbes and DNA in ancient halite / Russell H. Vreeland -- DNA replication and repair in halophiles / Adrienne Kish and Jocelyne DiRuggiero -- Gene transfer mechanisms, population genetics/genimics and the evolution of haloarchaea / R. Thane Papke and Scott Chimileski -- Worth your salt : halophiles in education / Bonnie K. Baxter, Jaimi K. Butler and Betsy Kleba -- Halophiles in the public media / Russell H. Vreeland.
  • 2010 Springer
    Abraham, David.
  • 2008 ScienceDirect
    Landgraf, Rainer; Neumann, Inga D.
    Nonapeptides and the evolutionary patterning of sociality / J.L. Goodson -- Sex differences in vasopressin and oxytocin innervation of the brain / G.J. de Vries -- The parvocellular vasopressinergic system and responsiveness of the hypothalamic pituitary adrenal axis during chronic stress / G. Auilera ... [et al.] -- Experimental approaches for the study of oxytocin and vasopressin gene expression in the central nervous system / E.M. Scordalakes, C. Yue and H. Gainer -- Oxytocin knockout mice: a model for studying stress-related and ingestive behaviours / J.A. Amico ... [et al.] -- The role of the vasopressin 1b receptor in aggression and other social behaviours / H.K. Caldwell, S.R. Wersinger and W.S. Young III -- Behavioural studies using temporal and spatial inactivation of the oxytocin receptor / H.-J. Lee ... [et al.] -- New aspects of oxytocin receptor function revealed by knockout mice: sociosexual behavior and control of energy balance / K. Nishimori ... [et al.] -- Regulation of vasopressin release by co-released neurotransmitters: mechanisms of purinergic and adrenergic synergism / C.D. Sladek and Z. Song -- Neuron-glia interactions in the rat supraoptic nucleus / S.H.R. Oliet ... [et al.] -- Dynamic synapses in the hypothalamic-neurohypophyseal system / K.J. Iremonger and J.S. Bains -- Endogenous modulators of synaptic transmission: cannabinoid regulation in the supraoptic nucleus / N.A. McDonald ... [et al.] -- Oxytocin and appetite / G. Leng ... [et al.] -- Neural mechanisms underlying the milk ejection burst and reflex / G.I. Hatton and Y.-F. Wang -- Oxytocin receptor signaling / D. Devost, P. Wrzal and H.H. Zingg -- Neurosteroids are excitatory in supraoptic neurons but inhibitory in the peripheral nervous system: it is all about oxytocin and progesterone receptors / C. Viero and G. Dayanithi -- Oxytocin receptors: ligand binding, signaling and cholesterol dependence / G. Gimpl ... [et al.] -- Opposite effects of oxytocin and vasopressin on the emotional expression of the fear response / D. Viviani and R. Stoop -- Multi-factorial somato-dendritic regulation of phasic spike discharge in vasopressin neurons / C.H. Brown ... [et al.] -- Neurophysiology of supraoptic neurons in C57/BL mice studied in three acute in vitro preparations / R. Sharif-Naeini ... [et al.] -- Effects of oxytocin on GABA signalling in the foetal brain during delivery / R. Khazipov, R. Tyzio and Y. Ben-Ari -- Central vasopressin and oxytocin release: regulation of complex social behaviours / A.H. Veenema and I.D. Neumann -- Interactions between dopamine and oxytocin in the control of sexual behavior / T.A. Baskerville and A.J. Douglas -- Steroidal/neuropeptide interactions in hypothalamus and amygdale related to social anxiety / E. Choleris ... [et al.] -- Functional magnetic resonance imaging and the neurobiology of vasopressin and oxytocin / C.F. Ferris -- Evolution of the arginine vasopressin 1a receptor and implications for mammalian social behaviour / G. Heckel and S. Fink -- Oxytocin, vasopressin and sociality / C.S. Carter ... [et al.] -- Neuropeptides and social behaviour: effects of oxytocin and vasopressin in humans / M. Heinrichs and G. Domes -- Chronic stress plasticity in the hypothalamic paraventricular nucleus / J.P. Herman, J. Flak and R. Jankord -- Keeping oxytocin neurons under control during stress in pregnancy / P.J. Brunton and J.A. Russell -- Rapid synapse-specific regulation of hypothalamic magnocellular neurons by glucocorticoids / S. Di and J.G. Tasker -- Vasopressin in the septum: not important versus casually involved in learning and memory - two faces of the same coin? / M. Engelmann -- Role of the endocannabinoid system in regulation of the hypothalamic-pituitary-adrenocortical axis / M.A. Steiner and C.T. Wotjak -- Molecular genetic studies of the arginine vasopressin 1a receptor (AVPR1a) and the oxytocin receptor (OXTR) in human behaviour: from autism to altruism with some notes in between / S. Israel ... [et al.] -- Oxytocin and experimental therapeutics in autism spectrum disorders / J.A. Bartz and E. Hollander -- Impact of prosocial neuropeptides on human brain function / A. Meyer-Lindenberg -- Peptide and non-peptide agonists and antagonists for the vasopressin and oxytocin V₁[a], V₁[b], V₂ and OT receptors: research tools and potential therapeutic agents / M. Manning ... [et al.] -- Affinity and efficacy of selective agonists and antagonists for vasopressin and oxytocin receptors: an "easy guide" to receptor pharmacology / B. Chini, M. Manning and G. Guillon -- Prevention of hypoxic brain oedema by the administration of vasopressin receptor antagonist OPC-31260 / A.H. Molnár ... [et al.] -- Characterization of a novel and selective V₁[B] receptor antagonist / M. Craighead ... [et al.] -- Molecular mechanisms of clinical concentrating and diluting disorders / R.W. Schrier -- Action-binding channels / Y. Noda and S. Sasaki -- Opposite potentiality of hypothalamic coexpressed neuropeptides, apelin and vasopressin in maintaining body-fluid homeostasis / C. Llorens-Cortes and F. Moos -- Recent discoveries in vasopressin-regulated aquaporin-2 trafficking / R.A. Fenton and H.B. Moeller -- Pathophysiological role of aquaporin-2 in impaired water excretion / S.-e. Ishikawa ... [et al.] -- Potential utility of aquaporin modulators for therapy of brain disorders / M.C. Papadopoulos and A.S. Verkman.
  • 2012 Springer
    Almeida, Alzira Maria Paiva de; Leal, Nilma Cintra.
    Also available: Print – 2012
  • 2012 CRCnetBASE
    Kohlstadt, Ingrid.
    "This book features chapters leading physicians in disease management applying the latest scientific advances linking nutrition to the clinical practice of medicine. Each chapter offers adjuncts to standard care, fewer side-effects, improved risk-reduction or added quality of life"--Provided by publisher.
  • Tracy Davis.
    Status: Not Checked OutLane Catalog Record
  • 2013 Springer
    Carmont, Michael R.; Mei-Dan, Omer.
    1. The Management of the Extreme Sports Athlete / Omer Mei-Dan and Michael R. Carmont -- 2. Rock and Ice Climbing / Volker Schöffl -- 3. Alpine Skiing and Snowboarding Injuries / Mike Langran -- 4. Skydiving / Anton Westman -- 5. BASE Jumping / Omer Mei-Dan -- 6. Whitewater Canoeing and Rafting / Jonathan P. Folland and Kate Strachan -- 7. Surfing Injuries / Andrew T. Nathanson -- 8. Kite Surfing and Snow Kiting / Mark Tauber and Philipp Moroder -- 9. Windsurfing / Daryl A. Rosenbaum and Bree Simmons -- 10. Sailing and Yachting / Michael R. Carmont -- 11. Mountain Biking Injuries / Michael R. Carmont -- 12. Paragliding / Lior Laver and Omer Mei-Dan -- 13. Mountain, Sky, and Endurance Running / Denise Park and Michael R. Carmont -- 14. Personality Characteristics in Extreme Sports Athletes: Morbidity and Mortality in Mountaineering and BASE Jumping / Erik Monasterio -- 15. Endocrine Aspects and Responses to Extreme Sports / Karen Tordjman, Naama Constantini, and Anthony C. Hackney -- 16. Preventing Injuries in Extreme Sports Athletes / John Nyland and Yee Han Dave Lee -- 17. Rehabilitation of Extreme Sports Injuries / Peter Malliaras, Dylan Morrissey, and Nick Antoniou.
  • 2007 CRCnetBASE
    Kott, Alexander W.; McEneaney, William M.
    Featuring approaches that draw from disciplines such as artificial intelligence and cognitive modeling, this book describes technologies and applications that address a broad range of practical problems, including military planning and command, military and foreign intelligence, antiterrorism and domestic security, as well as simulation and training systems. The authors present an overview of each problem and then discuss approaches and applications, combining theoretical rigor with accessibility. This comprehensive volume covers intent and plan recognition, deception discovery, and strategy formulation.
  • 2012 Karger
    French, Lars E.
    "The skin is one of the most frequently involved organs in adverse drug reactions. Occurring with an incidence of 1 to 5 percent for certain types of drugs, cutaneous drug eruptions are mostly benign in nature, and comprise the maculopapular type of eruption and urticaria. However, about one third of them require hospital treatment, leading to a considerable burden for the health care system. In this book, a selected group of experts provide an up-to-date, condensed and clinically relevant overview of the field of cutaneous drug eruptions, ranging from epidemiology and genetic predisposition to available therapeutic measures, including rapid drug desensitization. Reflecting the great progress made in recent years in this field, this publication will be a useful tool for a better understanding, diagnosis and management of cutaneous drug eruptions, not only for general physicians, dermatologists and clinical allergologists, but also for nurses and scientists." -- publisher's site.
  • 2014 Springer
    Özkaya, Esen; Yazganoglu, K. Didem.
    This book describes adverse cutaneous drug reactions as among the most frequent events in patients receiving drug therapy. Cardiovascular drugs are an important group as there are a greater number of indications for the use of new drugs and their prescription continues to increase. The exact incidence of cutaneous side effects from cardiovascular drugs is difficult to estimate due to sporadic reporting. Moreover, a reliable connection between a certain drug and a certain type of reaction can only rarely be made, aside from the well-known angioedema/urticaria from angiotensin-converting enzyme inhibitors, lichen planus/lichenoid reaction from beta adrenergic blockers, and photosensitivity from thiazid diuretics. These reactions can extend to rare but life-threatening conditions such as erythroderma, Stevens-Johnson syndrome, toxic epidermal necrolysis and drug hypersensitivity syndrome. Adverse Cutaneous Drug Reactions To Cardiovascular Drugs reviews the reported types of reactions to cardiovascular drugs. Each is discussed according to drug class and the type of dermatologic reaction with special emphasize on cross-reactions and the role of patch testing in diagnosis. A total of 116 images are included featuring clinical appearance of common adverse cutaneous drug reactions and diagnostic procedures such as patch and photopatch testing with the suspected drugs. Complementary tables may allow to scan the most common cutaneous reactions and the related cardiovascular drugs along with the possible cross reactions at first glance. It will thus be of considerable importance to all dermatologists and medical professionals who manage the skin, while being an important reference resource for cardiologists in terms of identifying potential adverse reactions to the drugs they prescribe.
  • 2010 Springer
    Uetrecht, Jack P.
    Pt. 1. Target organ toxicity. -- Drug-induced liver injury / Michael Holt, Cynthia Ju.-- Drug herpersensitivity reactions involving skin / Oliver Hausmann, Benno Schnyder, Werner J. Pichler.-- Adverse drug reactions affecting blood cells / Richard H. Aster.-- Molecular mechanisms of adverse drug reactions in cardiac tissue / Reza Tabrizchi.-- Mechanisms of drug-induced nephrotoxicity / Thomas D. Nolin, Jonathan Himmelfarb.-- Receptor- and reactive intermediate-mediated mechanisms of teratogenesis / Peter G. Wells, Crystal J.J. Lee, Gordon P. McCallum, Julia Perstin, Patricia A. Harper.-- Pt. II. Mediators/Biochemical pathways.-- Role of reactive metabolites in drug-induced hepatotoxicity / A.M. Srivastava, J. L. Maggs, D. J. Antoine, D. P. Williams, D. A. Smith, B. K. Park.-- Role of cytokines in the mechanism of adverse drug reactions / Mary Jane Masson, Lindsay A. Collins, Lance R. Poh.-- Keap1-Nrf2 cellular defense pathway: mechanisms of regulation and role in protection against drug-induced toxicity / Ian M. Copple, Christopher E. Goldring, Neil R. Kitteringham, B. Kevin Park.-- Signal transduction pathways involved in drug-induced liver injury / Derick Han, Mie Shinohara, Maria D. Ybanez, Behnam Saberi, Neil Kaplowitz.-- Mictrochondrial involvement in drug-induced liver injury / Dominique Pessayre, Abdellah Mansouri, Alain Berson, Bernard Fromenty.-- Pt. III. Examples/Models.-- Mechanisms of acetaminophen-induced liver necrosis / Jack A. Hinson, Dean W. Roberts, Laura P. James.-- Drug-induced liver injury in humans: the case of Ximelagtran / M. Keisu, T.B. Andersson.-- Troglitazone / Tsuyoshi Yokoi.-- Neviropine hypersensitivity / M. Popovic, J.M. Shenton, J. Chen, A. Baban, T. Tharmanathan, B. Mannargudi, D. Abdulla, J.P. Uetrecht.-- Mechanisms of adverse drug reactions to biologics / Janet B. Clarke.-- Pt. IV. Risk factors/Screening drug candidates.-- Pharmacogenetics of idiosyncratic adverse drug reactions / Munir Pirmohamed.-- Danger hypothesis applied to idiosyncratic drug reactions / Jinze Li, Jack P. Uetrecht.-- Approaches for minimizing metabolic activation of new drug candidates in drug discovery / Sanjeev Kumar, Kaushik Mitra, Kelem Kassahun, Thomas A. Baillie.
  • 2012 ScienceDirect
    Fadeel, Bengt; Pietroiusti, Antonio; Shvedova, Anna A.
    A. Engineered nanomaterials: hazard, exposure and safety assessment. Interactions with the human body / Renato Colognato ... [et al.] -- Exposure assessment / Antonio Bergamaschi, Ivo Iavicoli and Kai Savolainen -- Biomonitoring / Enrico bergamaschi and Andrea Magrini -- Critical evaluation of toxicity tests / Maria Dusinska ... [et al.] -- Computational approaches / Vidana Epa, Dave Winkler and Lang Tran -- Regulation and legislation / Maureen R. Gwinn and Birgit Sokull-Klüttgen -- B. Engineered nanomaterials: impact on human health. Respiratory system / Ken Donaldson and Craig Poland -- Cardiovascular system / Jennifer B. Raftis, Nicholas L. Mills and Rodger Duffin -- Neurological system / Sandra Ceccatelli and Giuseppe Bardi -- Immune system / Diana Boraschi and Albert Duschl -- Skin / Nancy A. Monteiro-Riviere and Francesca Larese Filon -- Gastrointestinal tract / Mark A. Jepson -- Reproductive toxicity / Karin Sørig Hougaard and Luisa Campagnolo -- Genotocicity and cancer / Shareen H. Doak, Ying Liu and Chunying Chen -- C. Biomedical applications of engineered nanomaterials. Diagnostic applications / Kalcheng and Zhen Cheng -- Therapeutic applications / Cyrill Bussy ... [et al.] -- Annex: synthesis of engineered nanomaterials / Muhammet S. toprak, Gulaim A. Seisenbaeva and Vadim G. Kessler.
  • 2014 Springer
    Tridente, G.
    This monograph gathers and evaluates data on adverse events (AEs) associated specifically with those 'biomedicines' - monoclonal antibodies, fusion proteins, and cytokines - that have recently entered therapeutic use in humans. All AEs observed when using each member of this new drug class are covered, with a view to improving understanding of pathogenesis, facilitating prevention, monitoring, and control, and contributing to the development of better drugs that provide benefits while minimizing risk. Further aspects here examined include the role of drug mechanisms of action and immunogenicity in relation to AEs outcome and induction of systemic syndromes. Additional data on AEs in off-label treatments are also considered. Electronic data sheets, downloadable from the Springer Extra Materials platform, include more detailed safety data as well as additional basic information on product characteristics, pre- and post-marketing AEs classified according to frequency, and system/organ targeting. Data on excipients and selected information on drug interactions and associations are also provided. Adverse Events with Biomedicines: Prevention Through Understanding will serve as a detailed, practical guideline to this important new area, which demands the attention of clinicians, immunologists, oncologists, allergologists, public health professionals, and drug companies.
  • 2013 Springer
    Colgan, Richard; Colgan, Richard.
    Part I. Inspirational Perspectives from History -- -- Introduction -- Ancient times -- Chinese and medieval medicine -- The twentieth century -- Modern masters -- -- Part II. Practical Advice for the Modern-Day Healer -- -- Survival tips for the younger clinician -- Civility -- Lessons learned from private practice -- A doctor's journal -- Heal thyself -- The healer.
  • 2009 Springer
    Colgan, Richard.
  • 2013 ScienceDirect
    Fisher, Paul B.; Sarkar, Devanand.
    Ch. 1. AEG-1/MTDH/LYRIC, the beginning: initial cloning, structure, expression profile, and regulation of expression -- Ch. 2. AEG-1/MTDH/LYRIC: clinical significance -- Ch. 3. AEG-1/MTDH/LYRIC: signaling pathways, downstream genes, interacting proteins, and regulation of tumor angiogenesis -- Ch. 4. Pleiotropic roles of AEG-1/MTDH/LYRIC in breast cancer -- Ch. 5. Drug resistance mediated by AEG-1/MTDH/LYRIC -- Ch. 6. The role of AEG-1/MTDH/LYRIC in the pathogenesis of central nervous system disease -- Ch. 7. AEG-1/MTDH/LYRIC in liver cancer -- Index.
  • 2013 CRCnetBASE
    Harley, Naomi H.; Ruzer, Lev S.
    Ch. 1. Medical and pharmaceutical aerosols / Stephen R. Marek ... [et al.] -- ch. 2. Breathing zone exposure assessment / Charles E. Rodes and Jonathan W. Thornburg -- ch. 3. Mechanisms of particle deposition / Jacky A. Rosati, Kristin K. Isaacs, and Ted B. Martonen -- ch. 4. Aerosol dose / Lev S. Ruzer, Michael G. Apte, and Richard G. Sextro -- ch. 5. Modeling deposition of inhaled particles / Kristin K. Isaacs, Jacky A. Rosati, and Ted B. Martonen -- ch. 6. Aerosol chemistry and physics / Lara A. Gundel and Hugo Destaillats -- ch. 7. Chemical analyses of particle filter deposits / Judith C. Chow and John. G. Watson -- ch. 8. Health effects of ambient ultrafine particles / Beverly S. Cohen -- ch. 9. Nanoparticle cell penetration / Steven M. Hankin and Craig A. Poland -- ch. 10. High aspect ratio nanomaterials : characterization and toxicology / Steven M. Hankin and Craig A. Poland -- ch. 11. Research and development of a new safe form of drugs / T.G. Tolstikova ... [et al.] -- ch. 12. Bioaerosols / Janet M. Macher ... [et al.] -- ch. 13. Aerosols, global climate, and the human health co-benefits of climate change mitigation / George D. Thurston and Michelle L. Bell -- ch. 14. Health effects of metals in ambient air particulate matter / Morton Lippmann -- ch. 15. Radioactive aerosols / Lev S. Ruzer -- ch. 16. Unattached fraction of radon progeny as an experimental tool in the assessment of the risk of nanoparticles / Lev S. Ruzer -- ch. 17. Filtration and sampling of aerosols by fibrous filters / A.K. Budyka, A.A. Kirsch, and B.I. Ogorodnikov -- ch. 18. Radioactive aerosols of Chernobyl accident / A.K. Budyka and B.I. Ogorodnikov -- ch. 19. Classical nucleation theory : account of dependence of the surface tension on curvature and translation-rotation correction factor / S.V. Vosel ... [et al.] -- ch. 20. Radioactive aerosol standards / Lev S. Ruzer ... [et al.] -- ch. 21. Radon and thoron in the environment : concentrations and lung cancer risk / Naomi H. Harley -- ch. 22. Risk from inhalation of the long-lived radionuclides uranium, thorium, and fallout plutonium in the atmosphere / Isabel M. Fisenne -- ch. 23. Health effects of aerosols : mechanisms and epidemiology / Ira B. Tager.
  • 2010 ClinicalKey
    Evans, Gregory R. D.; Hall-Findlay, Elizabeth J.
    Drs. Hall-Findlay and Evans' new Aesthetic and Reconstructive Surgery of the Breast has a purely surgical focus that covers the full scope of breast surgery. Coverage of hot topics includes new implant types, gel implants, fat injections to the breast for aesthetic enhancement, and fat injections for reconstruction. The book is organized into seven sections including reduction, mastopexy, augmentation, and more. Expert, international contributors deliver practical advice on the latest techniques, with a special emphasis on what can go wrong and how to avoid it. This full-color, templated reference comes with case studies and 16 video clips (both on web and on DVD) with approximately three hours of footage demonstrating key procedures. Video coverage includes form-stable high cohesive silicone gel implants, short scar with inferior pedicle, and sub-fascial breast augmentation. Expert Consult access enables you to search full text online and download images. Get practical advice on handling problems that occur in both reconstructive and aesthetic surgery Study various operative steps in depth with real-life clinical detail Avoid and/or deal with complications by referencing case examples and analyses with expert international counsel Watch the techniques first-hand with videos online and on the accompanying DVD, and watch experts performing the procedures Search the text's full content electronically, or download images and video for teaching purposes.
  • 2011 Springer
    Fodor, Lucian; Elman, Monica; Ullmann, Yehuda.
    Skin anatomy -- Light tissue interactions -- Intense pulsed light safety: legal issues -- How to organize the IPL treatment room -- Patient selection -- Skin photorejuvenation -- Hair removal -- IPL treatment for vascular lesions -- Complications.
  • 2009 ClinicalKey
    Bucky, Louis P.; Mottura, A. Aldo.
    Pre-operative evaluation, preparation and education of the breast augmentation patient -- Breast augmentation: incision selection -- Subpectoral approach for primary breast augmentation -- Saline implants: indications, techniques and precautions -- Silicone implants -- Semi-cohesive gel implants -- Subfascial transaxillary breast augmentation -- Secondary augmentation -- Breast reconstruction and augmentation using pre-expansion and autologous fat transplantation -- Tubular breasts -- Mastopexy: augmentation -- Periareolar/vertical/small horizontal scars -- Circumvertical breast reduction technique -- Vertical breast reduction -- Vertical mammaplasty -- No vertical scar breast reduction/mastopexy -- Breast shaping in the massive weight loss patient -- Complications in breast augmentation: maximizing patient outcomes with some surgical solutions to common problems.
  • 2010 ClinicalKey
    Cantisano-Zilkha, Marian; Haddad, Alessandra.
    Overview of the aesthetic approach -- Combining non-invasive therapies -- Skincare -- Chemical peels -- Lasers and intense light sources -- Photodynamic treatment -- Skin tightening devices -- Botulinum toxin for oculofacial aesthetic rejuvenation -- Facial fillers and volumizers -- Fat transfer -- Dark circles: a combination approach -- Minimally invasive laser lipolysis for facial and neck rejuvenation -- Mesotherapy -- Carbon dioxide therapy: face and body rejuvenation -- Cosmetic dentistry of the perioral area: the odontological point of view -- Importance of aesthetician in a cosmetic practice -- From the inside out: a psychotherapist's views on aesthetic enhancement -- Future of oculofacial rejuvenation: a perspective.
  • 2009 ClinicalKey
    Aston, Sherrell J.; Steinbrech, Douglas S.; Walden, Jennifer L.
    Office practice of plastic surgery -- Clinical photography for the aesthetic patient -- Anesthesia in aesthetic surgery -- Postoperative nausea and vomiting -- Patient safety in aesthetic surgery -- Facelift anatomy, SMAS, retaining ligaments and facial spaces -- Facelift with SMAS technique and FAME -- Facelift with SMAS technique and FAME -- Short scar facelift -- Foundation facelift -- The "High SMAS" facelift technique -- MACS facelift -- The multi-vectored rhytidoplasty -- The male facelift -- Endoscopic mid and lower face rejuvenation -- Endoscopic facial rejuvenation -- Facial rejuvenation in non-Caucasians -- Aesthetic facial microsurgery -- Midface lift -- Deep plane procedures in the neck -- Treatment of the male neck -- Managing submandibular glands -- Non-endoscopic limited incision browlift -- Coronal browlift -- Endoscopic browlift with internal fixation -- Transblepharoplasty browlift -- Suture suspension for face and neck -- Suture suspension for brow and upper face -- Conventional upper and lower blepharoplasty -- Lateral canthal suspension techniques -- Lid-cheek blending: the tear trough deformity -- Tarsal strip canthoplasty -- Blepharoplasty in the East Asian patient -- Treatment of blepharoplasty complications -- Autologous contouring the lower face -- Alloplastic chin augmentation -- Primary closed rhinoplasty -- Primary open rhinoplasty -- Secondary rhinoplasty -- Nasal tip grafting with an "anatomic tip graft" and sizers -- Nasal tip grafting with an "anatomic tip graft" and sizers -- Correction of the deviated septum -- The ethnic rhinoplasty -- The Asian rhinoplasty -- Correcting the cleft lip nose -- Primary otoplasty and reconstruction -- Traditional inverted-T breast reduction -- Mastopexy with and without augmentation -- Pitanguy breast reduction -- Medial pedicle vertical mammaplasty -- Periareolar Benelli mastopexy and reduction: The "Round Block" -- Breast implants: background, safety and general considerations -- Breast augmentation -- The dual plane approach to breast augmentation -- Cohesive gel breast augmentation -- Difficult breast augmentations -- Breast reconstruction -- Nipple - areola reconstruction -- Pure aspiration lipoplasty -- Complications and corrections of lipoplasty -- New concepts in fat grafting -- Lipoabdominoplasty: Saldanha's technique -- Lipoabdominoplasty: Advanced techniques and technologies -- Non-surgical ultrasonic lipoplasty -- Ultrasound assisted liposuction -- Abdominoplasty techniques -- Brachioplasty -- Belt lipectomy: Lower body lift -- High lateral tension abdominoplasty -- Gluteal augmentation -- Botox® for face, neck and brow -- Lip augmentation -- Structural fat augmentation of the face and hands -- Hyaluronic acid injectable filler -- Non-hyaluronic acid fillers for facial augmentation -- Laser resurfacing -- Fractional resurfacing -- Total facial alloplastic augmentation -- Chemical peels and dermabrasion.
  • 2012 ClinicalKey
    Guyuron, Bahman; Kinney, Brian M.
    Patient Assessment -- Skin Care Including Chemical Peeling -- Non-surgical Facial Rejuventation with Fillers -- Botulinum Toxin -- Laser Facial Resurfacing and Dermabrasion -- Management of Alopecia -- Forehead Rejuvenation -- Periorbital Rejuvenation -- Facelift with SMAS Flaps -- Neck Rejuvenation -- Primary Rhinoplasty -- Secondary Rhinoplasty -- Genioplasty -- Aesthetic Contouring of the Craniofacial Skeleton -- Augmentation of Facial Structures with Autologous Fat -- Breast Augmentation -- Breast Reduction -- Mastopexy -- Liposculpture -- Abdominoplasty -- Bodylifts and Post Massive Weight Loss Body Contouring -- Surgical Management of Migraine Headaches.
  • 2016 Springer
    Çakir, Bariş.
  • 2015 Springer
    Mugea, Toma T.; Shiffman, Melvin A.
    This book covers all aspects of aesthetic breast surgery in an instructive, step-by-step format. The descriptions of procedures are completely up to date, encompassing newly introduced techniques and recent modifications of established techniques. Individual parts of the book are devoted to breast augmentation, mastopexy, and breast reduction. Detailed consideration is also given to risks and complications, with guidance on their avoidance and the treatment of complications. In addition, anatomy, anesthesia, and a range of miscellaneous procedures applicable in specific circumstances are all well covered. The authors are acknowledged experts in their fields who draw on a wealth of experience in describing and illustrating their personally favored techniques. Aesthetic Surgery of the Breast will be an ideal reference for both students (residents and fellows) and practicing cosmetic, plastic, and general surgeons.
  • 2007 Springer
    Panfilov, Dimitrije E.
  • 2008 Ovid
    Grimes, Pearl E.
  • 2010 Karger
    Staudenmaier, Rainer.
    History of auricular reconstruction / Weerda, H. -- State-of-the-art autogenous ear reconstruction in cases of microtia / Firmin, F. -- Ear reconstruction with porous polyethylene implants / Berghaus, A. ... [et al.] -- Auricular prostheses / Federspil, P.A. -- Combined aesthetic and functional reconstruction of ear malformations / Kiefer, J., Staudenmaier, R. -- Combined reconstruction of congenital auricular atresia and severe microtia / Siegert, R. -- Ear reconstruction through tissue engineering / Haisch, A. -- Customized tissue engineering for ear reconstruction / Staudenmaier, R. ... [et al.].
  • 2008 Springer
    Malone, P. Colm; Agutter, Paul S.
  • 2008 Springer Protocols
    Zachariou, Michael.
    Affinity chromatography : history, perspectives, limitations, and prospects / Ana Cecília A. Roque and Christopher R. Lowe -- Immobilized metal ion affinity chromatography of native proteins / Adam Charlton and Michael Zachariou -- Affinity precipitation of proteins using metal chelates / Ashok Kumar, Igor Yu. Galaev, and Bo Mattiasson -- Immunoaffinity chromatography / Stuart R. Gallant, Vish Koppaka, and Nick Zecherle -- Dye ligand chromatography / Stuart R. Gallant, Vish Koppaka, and Nick Zecherle -- Purification of proteins using displacement chromatography / Nihal Tugcu -- Rationally designed ligands for use in affinity chromatography : an artificial protein L / Ana Cecília A. Roque and Christopher R. Lowe -- Phage display of peptides in ligand selection for use in affinity chromatography / Joanne L. Casey, Andrew M. Coley, and Michael Foley -- Preparation, analysis, and use of an affinity adsorbent for the purification of GST fusion protein / Gareth M. Forde -- Immobilized metal ion affinity chromatography of histidine-tagged fusion proteins / Adam Charlton and Michael Zachariou -- Methods for the purification of HQ-tagged proteins / Becky Godat ... [et al.] -- Amylose affinity chromatography of maltose-binding protein : purification by both native and novel matrix-assisted dialysis refolding methods / Leonard K. Pattenden and Walter G. Thomas -- Methods for detection of protein-protein and protein-DNA interactions using HaloTag / Marjeta Urh ... [et al.] -- Site-specific cleavage of fusion proteins / Adam Charlton -- The use of TAGZyme for the efficient removal of N-terminal his-tags / José Arnau ... [et al.] -- Affinity processing of cell-containing feeds using monolithic macroporous hydrogels, cryogels / Igor Yu. Galaev and Bo Mattiasson -- Monolithic bioreactors for macromolecules / Mojca Benčina ... [et al.] -- Plasmid DNA purification via the use of a dual affinity protein / Gareth M. Forde -- Affinity chromatography of phosphorylated proteins / Grigoriy S. Tchaga -- Protein separation using immobilized phospholipid chromatography / Tzong-Hsien Lee and Marie-Isabel Aguilar -- Analysis of proteins in solution using affinity capillary electrophoresis / Niels H.H. Heegaard, Christian Schou, and Jesper Østergaard.
  • 2015 Springer Protocols
    Reichelt, Senta.
    Affinity chromatography : a historical perspective -- Protein purification by amniosquarylium cyanine dye-affinity chromatography -- One-step purification of phosphinothricin acetyltransferase using reactive dye-affinity chromatography -- Antibody purification from human plasma by metal-chelated affinity membranes -- Specific recognition of supercoiled plasmid DNA by affinity chromatography using a synthetic aromatic ligand -- Cell affinity separations on microfluidic devices -- Aptamer-modified magnetic beads in affinity separation of proteins -- The Strep-tag system for one-step affinity purification of proteins from mammalian cell culture -- Robotic high-throughput purification of affinity-tagged recombinant proteins -- Macroporous silica particles derivatized for enhanced lectin affinity enrichment of glycoproteins -- Immobilized magnetic beads-based multi-target affinity selection coupled with HPLC-MS for screening active compounds from traditional Chinese medicine and natural products -- Mixed-bed affinity chromatography : principles and methods -- Preparation and characterization of fluorophenylboronic acid-functionalized affinity monolithic columns for the selective enrichment of cis-diol-containing biomolecules -- Introduction to macroporous cryogels -- Cryogels with affinity ligands as tools in protein purification -- Direct capture of His₆-tagged proteins using megaporous cryogels developed for metal-ion affinity chromatography -- Ni(II) chelated IDA functionalized poly(HEMA-GMA) cryogels for urease adsorption -- A novel chromatographic media : histidine-containing composite cryogels for HIgG separation from human serum -- Molecularity imprinted cryogels for human serum albumin depletion -- Interpenetrating polymer network composite cryogels with tailored porous morphology and sorption properties -- Analysis of drug-protein interactions by high-performance affinity chromatography : interactions of sulfonylurea drugs with normal and glycated human serum albumin -- Accurate protein-peptide titration experiments by nuclear magnetic resonance using low-volume samples -- Characterization of the binding strengths between boronic acids and cis-diol-containing biomolecules by affinity capillary electrophoresis -- Determination if the kinetic rate constant of cyclodextrin supramolecular systems by high-performance affinity chromatography -- Molecular modeling of the affinity chromatography of monoclonal antibodies.
  • 2014 Springer
    Selker, Harry P.; Wasser, June S.
    This book examines the landmark 2010 Patient Protection and Affordable Care Act (ACA) from the perspective that health policy innovation is translational research directed at improving health. It delineates a new perspective about the creation and potential impact of the ACA and guides the development of health policy that is supported by best evidence that, in turn, transforms into practice, policy, and public benefit. Told by those involved in the creation and implementation of the ACA, the book reviews the history and impact of this ground-breaking legislation and recommends priorities, objectives, and next steps for translational research as the ACA is implemented. Featuring contributions from nationally renowned leaders in healthcare policy, this book adds to the public conversation about the ACA and its role in shaping health policy and contributes to a more realistic, nuanced, and productive understanding of this ground-breaking legislation by physicians, policy makers, and the public. It also provides a framework for next steps in continuing to improve U.S. health policy.
  • 2013
    Haseltine, William A.
    The Singapore healthcare system : an overview -- High quality, low cost -- Helping patients pay -- Controlling costs -- Financing -- Design and infrastructure -- Investing in the future through medical education and research -- Facing the future.
  • 2015
    Viveiros, Janet.
    This report examines several ways in which health care changes created by the ACA, and other health care reform initiatives, create the potential for affordable housing providers to collaborate with health care providers, insurers, and other institutions to support the wellbeing of low-income individuals and families.
  • 2010 Springer
    Jones, Kenneth T.; McCree, Donna Hubbard; O'Leary, Ann.
    The HIV/AIDS epidemic is burgeoning among African American men and women. Despite comprising only 13 percent of the population, 50 percent of new HIV diagnoses in 2004 were among African Americans. Among women and men who have sex with men (MSM), African Americans are grossly disproportionately affected by this epidemic, and this trend shows no sign of abating. This book seeks to explore some of the contextual factors that contribute to this disparity as well as ways to intervene to slow the growth of the epidemic in the U.S. This volume will focus on the history and context of HIV/AIDS in African Americans and interventions targeting specific subpopulations including adolescents, heterosexual men and women, men who have sex with men, incarcerated populations, and injection drug users. Context chapters will focus on specific contextual and structural issues related to HIV/AIDS transmission and prevention in African Americans including disparities in incarceration, racism, economic issues and substance abuse. Intervention chapters will focus on best-evidence and promising-evidence based interventions targeting HIV prevention in African Americans. These chapters will address the latest in intervention strategies, program evaluation, cost effectiveness and qualitative research methods and will include risk reduction, risk assessment, and testing and counseling.
  • 2013 IngentaConnect
    Richardson, Angelique.
    1. Love and hatred are common to the whole sensitive creation: animal feeling in the century before Darwin -- 2. 'The Book of the Season': the conception and reception of Darwin's Expression -- 3. The backbone shiver: Darwin and the arts -- 4. Becoming an animal: Darwin and the evolution of sympathy -- 5. George Eliot, G.H. Lewes, and Darwin: animals, emotions, and morals -- 6. Between medicine and evolutionary theory: sympathy and other emotional investments in life writings by and about Charles Darwin -- 7. From entangled vision to ethical engagement: Darwin, affect, and contemporary exhibition projects -- 8. Reckoning with the emotions: neurological responses to the theory of evolution, 1870-1930 -- 9. Darwin's changing Expression and the making of the modern state -- 10. Calling the wild: selection, domestication, and species -- 11. The development of emotional life -- Afterword. The emotional and moral lives of animals: what Darwin would have said -- Index.
    Also available: Print – 2013
  • 2013 ebrary
    Herrick, James A.; Hyde, Michael J.
    Faith in science : professional and public discourse on regenerative medicine / Tristan Keys, Nancy M. P. King, and Anthony Atala -- From Arrowsmith to Atwood : how did we come to disrespect science? / Ronald M. Green -- The "warfare" of science and religion and science's ethical profile / Thomas M. Lessl -- Is there a human nature? : an argument against modern excarnation / Jean Bethke Elshtain -- Crossing frontiers of science : trespassing into a godless space, or, Fulfilling our manifest destiny / Leah Ceccarelli -- The angels and devils of representing Prozac / Tod Chambers -- "Leave your medicine outside" : bioethics, spirituality, and the rhetoric of Appalachian serpent handlers / Bill J. Leonard -- Biovaluable stories and a narrative ethics of reconfigurable bodies / Arthur W. Frank -- Blacks and the language of their biotechnological future / Ezra E. H. Griffith -- Bioethics, economism, and the rhetoric of technological innovation / Howard Brody -- Technologies of the self at the end of life : pastoral power and the rhetoric of advance care planning / Lisa Kernen -- Suffering and the rhetoric of care / Judy Segal.
  • 2008
    Heinrich, Larissa.
    "In 1739 China's emperor authorized the publication of a medical text that included images of children with smallpox to aid in the diagnosis and treatment of the disease. Those images made their way to Europe, where they were interpreted as indicative of the ill health and medical backwardness of the Chinese. In the mid-nineteenth century, the celebrated Cantonese painter Lam Qua collaborated with the American medical missionary Peter Parker in the creation of portraits of Chinese patients with disfiguring pathologies, rendered both before and after surgery. Europeans saw those portraits as evidence of Western medical prowess. Within China, the visual idiom that the paintings established influenced the development of medical photography. In The Afterlife of Images, Larissa N. Heinrich investigates the creation and circulation of Western medical discourses that linked ideas about disease to Chinese identity beginning in the eighteenth century." "Combining literary studies, the history of science, and visual culture studies, Heinrich analyzes the rhetoric and iconography through which medical missionaries transmitted to the West an image of China as "sick" or "diseased" She also examines the absorption of that image back into China through missionary activity, through the earliest translations of Western medical texts into Chinese, and even through the literature of Chinese nationalism. Heinrich argues that over time "scientific" Western representations of the Chinese body and culture accumulated a host of secondary meanings, taking on an afterlife with lasting consequences for conceptions of Chinese identity in China and beyond its borders."--Jacket.
  • 2013
    Hornblum, Allen M.; Dober, Gregory J.; Newman, Judith L.
    "The sad history of young children, especially institutionalized children, being used as cheap and available test subjects - the raw material for experimentation - started long before the atomic age and went well beyond exposure to radioactive isotopes. Experimental vaccines for hepatitis, measles, polio and other diseases, exploratory therapeutic procedures such as electroshock and lobotomy, and untested pharmaceuticals such as curare and thorazine were all tested on young children in hospitals, orphanages, and mental asylums as if they were some widely accepted intermediary step between chimpanzees and humans. Occasionally, children supplanted the chimps. Bereft of legal status or protectors, institutionalized children were often the test subjects of choice for medical researchers hoping to discover a new vaccine, prove a new theory, or publish an article in a respected medical journal. Many took advantage of the opportunity. One would be hard-pressed to identify a researcher whose professional career was cut short because he incorporated week-old infants, ward-bound juvenile epileptics, or the profoundly retarded in his experiments. In short, involuntary, non-therapeutic, and dangerous experiments on children were far from an unusual or dishonorable endeavor during the last century."--Provided by publisher.
  • 2007 CRCnetBASE
    Dangour, Alan D.; Fletcher, Astrid E.; Grundy, Emily M. D.
    Nutritional concerns in old age / Lisette C.P.G.M. de Groot and Wija A. van Staveren -- Regular exercise, the best investment for our old age / Marion E.T. McMurdo -- Major eye diseases of later life: cataract and age related macular degeneration / Astrid E. Fletcher -- Reminiscence in everyday talk between older people and their carers: implications for the quality of life of older people in care homes / Fiona Wilson ... [et al.] -- Retention of cognitive function in old age: why initial intelligence is important / Lawrence J. Whalley -- Health inequalities in old age in Britain / Elizabeth Breeze -- Demographic change, family support, and ageing well: developed country perspectives / Emily M.D. Grundy -- Energy efficiency and health of older people / Paul Wilkinson -- Ageing, health, and welfare: an economic perspective / Charles Normand -- Methodological issues in assessing the cost-effectiveness of interventions to improve the health of older people / Damian Walker and Cristian Aedo -- Minimum income for healthy living: older people England 2005-2006 / Jerry Morris ... [et al.] -- Responding to increasing human longevity: policy, practice, and research / David Metz.
  • 2013
    Zhavoronkov, Alex.
    Status: Not Checked OutLane Catalog Record
    "Over the past twenty years, the biomedical research community has been delivering hundreds of breakthroughs expected to extend human lifespan beyond thresholds imaginable today. However, much of this research has not yet been adopted into clinical practice, nor has it been widely publicized. Just as the Internet and mobile communications were interwoven into our everyday lives over the past two decades, biomedicine will transform our society forever by allowing people to live longer and to continue working and contributing financially to the economy longer, rather than entering into retirement and draining the economy through pensions and senior healthcare. With a refocusing of medical national resources to regenerative medicine, old age will become a concept of the past, breakthroughs in regenerative medicine will continue, and an unprecedented boom to the global economy, with an influx of older able-bodied workers and consumers, will be a reality. A leading expert in aging research, author Alex Zhavoronkov provides a helicopter view on the progress science has already made, from repairing tissue damage to growing functional organs from a single cell, and illuminates the possibilities that the scientific and medical community will soon make into realities. The Ageless Generation is an engaging work that causes us to rethink our ideas of age and ability in the modern world"-- Provided by publisher.
  • 2008 Springer
    Annicchiarico, Roberta; Cortés, U.; Urdiales, Cristina.
  • 2008 Springer
    Cavallotti, Carlo; Cerulli, Luciano.
    Aging as risk factor in eye disease -- Age-related changes of the eyelid -- Aging effects on the optics of the eye -- Aging of the cornea -- The aging of the human lens -- The extracellular matrix of the aged human trabecular meshwork: changes of glucosaminoglycans -- Glial and mobile cells in the iris of the aging human eye -- Age-related diseases of the vitreous -- Age-related changes and/or diseases in the human retina -- Aging of the retinal pigmented epithelium -- The aging of the choroid -- Age-related macular degeneration I: types and future directions -- Age-related macular degeneration II: idiopathic macular holes -- Age-related macular degeneration III: epiretinal membranes -- Macular degeneration: ultrastructural age-related changes -- Non-exudative macular degeneration and management -- Treatment of intraocular pressure in elderly patients -- Aging of the lachrymal [lacrimal] gland -- The world according to blink: blinking and aging -- Age-related changes in the oculomotor system -- Rehabilitation of low vision in aged people -- Many suggestions to protect the eyes in aging people.
    Also available: Print – 2008
  • 2011 Springer
    Ho, Allen C.; Regillo, Carl D.
    1. Genetics of Age-Related Macular Degeneration / Daniel T. Kasuga, Yuhong Chen, and Kang Zhang -- 2. Modifiable Risk Factors of Age-Related Macular Degeneration / Hanna R. Coleman -- 3. Diagnosis of Age-Related Macular Degeneration / Jonathan Jonisch and Gaurav Shah -- 4. Fundus Imaging of Age-Related Macular Degeneration / Allen Chiang, Andre J. Witkin, Carl D. Regillo, and Allen C. Ho -- 5. Therapy of Nonexudative Age-Related Macular Degeneration / Annal D. Meleth, Veena R. Raiji, Nupura Krishnadev, and Emily Y. Chew -- 6. Management of Neovascular AMD / Fernando M. Penha and Philip J. Rosenfeld -- 7. Combination Therapy with Ocular Photodynamic Therapy for Age-Related Macular Degeneration / Nathan Steinle and Peter K. Kaiser -- 8. The Future of Non-neovascular Age-Related Macular Degeneration / Ketan Laud, Sri Krishna Mukkamala, Claudia Brue, and Jason S. Slakter -- 9. The Future of Neovascular Age-Related Macular Degeneration / Chirag P. Shah and Jeffrey S. Heier -- 10. The Economics of Age-Related Macular Degeneration / Gary C. Brown, Melissa M. Brown, Heidi B. Lieske, Philip A. Lieske, and Kathryn Brown.
  • 2008
    Lim, Jennifer I.
    Status: Not Checked OutLane Catalog Record
    Histopathology of age-related macular degeneration / Shin J. Kang and Hans E. Grossniklaus -- Immunology of age-related macular degeneration / Karl G. Csaky and Scott W. Cousins -- Genetics of age-related macular degeneration / Jennifer R. Chao, Amani A. Fawzi, and Jennifer I. Lim -- Risk factors for age-related macular degeneration and choroidal neovascularization / Kah-Guan Au Eong ... [et al.] -- Choroidal neovascularization / Frances E. Kane and Peter A. Campochiaro -- Non-exudative age-related macular degeneration / Neelakshi Bhagat and Christina J. Flaxel -- Geographic atrophy / Sharon D. Solomon and Janet S. Sunness -- Exudative (neovascular) age-related macular degeneration / Jennifer I. Lim and Jerry W. Tsong -- Indocyanine green angiography in age-related macular degeneration / Scott C.N. Oliver ... [et al.] -- Optical coherence tomography in the evaluation and management of age-related macular degeneration / David Eichenbaum and Elias Reichel -- Quantitative retinal imaging / Daniel D. Esmaili ... [et al.] -- Fundus autofluorescence in age-related macular degeneration / Rishi P. Singh, Jeffrey Y. Chung, and Peter K. Kaiser -- Laser photocoagulation for choroidal neovascularization / Catherine Cukras and Stuart L. Fine -- Photocoagulation of AMD-associated CNV feeder vessels: an optimized approach / Robert W. Flower -- Photodynamic therapy / ATul Jain, Darius M. Mosfeghi, and Mark S. Blumenkranz -- Radiation treatment in age-related macular degeneration / Christina J. Flaxel and Paul T. Finger -- Anti-VEGF drugs and clinical trials / Todd R. Klesert, Jennifer I. Lim, and Phillip J. Rosenfeld -- Laser prophylaxis for age-related macular degeneration / Jason Hsu and Allen C. Ho -- Macular translocation / Kah-Guan Au Eong ... [et al.] -- Age-related macular degeneration : use of adjuncts in surgery and novel surgical approaches / Richard Scartozzi and Lawrence P. Chong -- Clinical consideration for visual rehabilitation / Susan A. Primo -- Retinal prostheses : a possible treatment for end-stage age-related macular degeneration / Thomas M. O'Hearn ... [et al.] -- Retinal pigment epithelial cell transplantation and macular reconstruction for age-related macular degeneration / Lucian V. Del Priore, Henry J. Kaplan, and Tongalp H. Tezel -- Clinical research trials / A. Frances Walonker and Kenneth R. Diddie.
  • 2013 Springer
    Bird, Alan C.; Holz, Frank G.; Pauleikhoff, Daniel; Spaide, Richard F.
    pt. 1. Pathophysiology. Epidemiology of AMD / L. Ho, R. van Leeuwen, P. T. V. M. de Jong, J. R. Vingerling and C. C. W. Klaver -- Genetics / L. G. Fritsche, U. Friedrich and B. H. F. Wxeber -- Ageing of the Retina and Retinal Pigment Epithelium / M. E. Boulton -- The Complement System in AMD / P. Charbel Issa, N. V. Chong and H. P. N. Scholl -- Histopathology / A. Lommatzsch, S. Wasmuth, D. Pauleikhoff, F. G. Holz and A. C. Bird -- pt. 2. Clinical Manifestations. Early AMD / M. Dietzel, D. Pauleikhoff, F. G. Holz and A. C. Bird -- Clinical Manifestations of Choroidal Neovascularization in AMD / R. F. Spaide -- Geographic Atrophy / M. Fleckenstein, S. Schmitz-Valckenberg, J. S. Sunness and F. G. Holz -- pt. 3. Diagnostics. Fundus Imaging of AMD / R. F. Spaide -- Optical Coherence Tomography / S. Wolf -- Microperimetry / E. Midena and E. Pilotto -- pt. 4. Prophylaxis and Therapy. Nutritional Supplementation in AMD / A. D. Meleth, V. R. Raiji, N. Krishnadev and E. Y. Chew -- Laser Photocoagulation and Photodynamic Therapy / G. Soubrane -- Anti-VEGF Therapy: Basics and Substances / S. Grisanti, J. Lüke and S. Peters -- Anti-VEGF Therapy for AMD: Results and Guidelines / P. Mitchell and S. Foran -- Combination Therapies for the Treatment of AMD / M. Barakat, N. Steinle and P. K. Kaiser -- Treatment Approaches for Dry AMD / Z. Yehoshua and P. J. Rosenfeld -- Surgical Therapy / B. Kirchhof -- pt. 5. Rehabilitation. Reading with AMD / S. Trauzettel-Klosinski -- Low Vision Aids in AMD / K. Rohrschneider.
  • 2014 Karger
    Fülöp, Tamas; Robert, Ladislas.
    The Commitment of human cells to senescence / R. Holliday -- Evolutionary theories of aging can explain why we age / E. Le Bourg -- Control of cell replication during aging / A. Macieira-Coelho -- Cell senescence : role in aging and age-related diseases / J. Campisi, L. Robert, -- Aging of cell membranes : facts and theories / I. Zs.-Nagy -- Oxidative stress, mitochondrial dysfunction, and the mitochondria theory of aging / Y. Kong, S.E. Trabucco, H. Zhang -- Aging of connective tissues : experimental facts and theoretical considerations / J. Labat-Robert, L. Robert -- Aging of cell communication : loss of receptor function / L. Robert, T. Fulop -- On the immunological theory of aging / T. Fulop, J.M. Witkowski, G. Pawelec, C. Alan, A. Larbi -- Aging of the brain, dementias, role of infectious proteins : facts and theories / F. Morinet -- Aging as alteration / P.-A. Miquel -- Longevity and its regulation : centenarians and beyond / L. Robert, T. Fulop.
  • 2007 Springer
    Holliday, R.
    Longevity -- Body architecture -- Maintenance of the body -- Multiple causes -- The ancient origins of ageing -- Mice and men -- How many genes? -- The evolution of human longevity -- Myths of life extension -- Doctors' dilemma -- The modulation of longevity -- Ageing and the angels -- Longevity, population pressure and warfare -- Dialogue between life and death -- The road discovery -- Resolution of the paradox.
  • v. 1-3, 1981-83
    Danon, D.; Marois, M.; Shock, Nathan W.
    Status: Not Checked OutLane Catalog Record
    v. 1. Biology / edited by D. Danon, N.W. Shock, and M. Marois.--v. 2. Medicine / edited by A.J.J. Gilmore, A. Svanborg, M. Marois. Social sciences and social policy / edited by Walter M. Beattie, Jr., Jerzy Piotrowski, M. Marois.--v. 3. Behavioural sciences / edited by James E. Birren ... [et al.]. Conclusions and perspectives / edited by Maurice Marois.
  • 2010 Springer
    Bondy, Stephen C.; Maiese, Kenneth.
    Part 1. General Aspects of Aging -- Protein Redox-Regulation Mechanisms in Aging / Ufuk Çakatay -- Nitrosative Stress in Aging - Its Importance and Biological Implications in NF-κB Signaling / Predrag Ljubuncic, Einat Gochman and Abraham Z. Reznick -- Intervention with Multiple Micronutrients Including Dietary and Endogenous Antioxidants for Healthy Aging / Kedar N. Prasad -- Advanced Glycation End Products, RAGE, and Aging / Ravichandran Ramasamy, Loredana G. Bucciarelli, Shi Fang Yan and Ann Marie Schmidt -- Sirtuins and Mammalian Aging / Edward H. Sharman -- Estrogenic Modulation of Longevity by Induction of Antioxidant Enzymes / Jose Viña, Consuelo Borrás, Mari Carmen Gómez-Cabrera, Juan Gambini and Raul López-Grueso, et al. -- Mitochondrial Respiratory Function Decline in Aging and Life-Span Extension by Caloric Restriction / Shi-Bei Wu, Yu-Ting Wu, Chih-Hao Wang, Wan-Yu Lee and Yau-Huei Wei -- Methylglyoxal, Oxidative Stress, and Aging / Miklós Péter Kalapos, Kaushik M. Desai and Lingyun Wu -- Part 2. The Cardiovascular System -- Novel Strategies for Neurovascular Longevity During Aging / Kenneth Maiese, Zhao Zhong Chong, Jinling Hou and Yan Chen Shang -- Oxidative Stress in Vascular Disease / Isabelle Gorenne and Martin R. Bennett -- The Role of Mitochondrial Reactive Oxygen Species Formation for Age-Induced Vascular Dysfunction / Andreas Daiber, Joachim Kienhoefer, Rebecca Zee, Philip Wenzel and Volker Ullrich, et al. -- Aging, Oxidative Stress, and Cardiovascular Disorders / Yi Shi, Giovanni G. Camici and Thomas F. Lüscher -- Oxidative Stress, Aging, and Cardiovascular Disease / G. Riccioni, V. Sblendorio and N. D'Orazio -- Antioxidation in Prevention of Cardiovascular Diseases - An Effect of Polyphenols / Jun-ichi Suzuki, Mitsuaki Isobe, Ryuichi Morishita and Ryozo Nagai -- Vascular Aging and Oxidative Stress: Hormesis and Adaptive Cellular Pathways / Nathalie Thorin-Trescases and Eric Thorin -- Role of Oxidative Stress in Mediating Elevated Blood Pressure with Aging / Julio Sartori Valinotti, Licy Yanes and Jane F. Reckelhoff -- Part 3. The Nervous System -- Melatonin, Oxidative Stress, and the Aging Brain / Stephen Bondy and Edward H. Sharman -- The SAM Strain of Mice, a Higher Oxidative Stress, Age-Dependent Degenerative Disease, and Senescence Acceleration Model / Yoichi Chiba, Atsuyoshi Shimada and Masanori Hosokawa -- Antioxidants Combined with Behavioral Enrichment Can Slow Brain Aging / Elizabeth Head -- Role of Nitric Oxide in Neurodegeneration and Vulnerability of Neuronal Cells to Nitric Oxide Metabolites and Reactive Oxygen Species / Debomoy K. Lahiri, Chandramallika Ghosh, Jack T. Rogers, Stephen Bondy and Nigel H. Greig -- Free Radical-Mediated Damage to Brain in Alzheimer's Disease: Role of Acrolein and Preclinical Promise of Antioxidant Polyphenols / Charles Ramassamy, Madeleine Arseneault and Dang Thanh Nam -- An Epigenetic Model for Susceptibility to Oxidative DNA Damage in the Aging Brain and Alzheimer's Disease / Nasser H. Zawia and Fernando Cardozo-Pelaez.
  • 2007 Springer
    Morewitz, Stephen John; Goldstein, Mark L.
  • 2015 Karger
    Jazwinski, S. Michal; Yashin, Anatoli I.
    Introduction to the theory of aging networks / Witten, T.M. -- Applications to aging networks / Wimble, C., Witten, T.M. -- Computational systems biology for aging research / Auley, M.T., Mooney, K.M. -- How does the body know how old it is? Introducing the epigenetic clock hypothesis / Mitteldorf, J. -- The great evolutionary divide : two genomic systems biologies of aging / Rose, M.R., Cabral, I.G., Philips, M.A., Rutledge, G.A., Phung, K.H., Mueller, L.D., Greer, L.F. -- Development and aging : two opposite but complementary phenomena / Feltes, B.C., De Faria Poloni, J., Bonatto, D. -- Aging as a process of deficit accumulation : its utility and origin / Mitnitski, A., Rockwood, K. -- Low-grade systemic inflammation connects aging, metabolic syndrome and cardiovascular disease / Guarner, V., Rubio-Ruiz, M.E. -- Modulating mTOR in aging and health / Johnson, S.C., Sangesland, M., Kaeberlein, M., Rabinovitch, P. -- Melatonin and circadian oscillators in aging : a dynamic approach to the multiply connected players / Hardeland, R. -- Diet-microbiota-health interactions in older subjects : implications for healthy aging / Lynch, D.B., Jeffery, I.B., Cusack, S., O'Connor, E.M., O'Toole, P.W. -- Systems biology approaches in aging research / Chauhan, A., Liebal, U.W., Vera, J., Baltrusch, S., Junghanss, C., Tiedge, M., Fuellen, G., Wolkenhauer, O., Köhling, R. -- Conservative growth hormone/IGF-1 and mTOR signaling pathways as a target for aging and cancer prevention : do we really have an antiaging drug? / Anisimov, V.N.
  • 2014 Springer
    Jugdutt, Bodh I.
    This book synthesizes the major research advances in molecular, biochemical, and translational aspects of aging and heart failure over the last four decades and addresses future directions in management and drug discovery. It presents clinical issues and molecular mechanisms related to heart failure, including the changing demographics in the aging population with heart failure; hypertension and prevention of diastolic heart failure in the aging population; polypharmacy and adverse drug reactions in the aging population with heart failure; changes in the heart that accompany advancing age from humans to molecules; aging-associated alterations in myocardial inflammation and fibrosis; and aging-related changes in mitochondrial function and implications for heart failure therapy. The book succinctly summarizes the large volume of data on these key topics and highlights novel pathways that need to be explored. Featuring contributions from leading clinician-scientists, Aging and Heart Failure: Mechanisms and Management is an authoritative resource on the major clinical issues in heart failure therapy in the elderly for cardiologists, gerontologists, and internists.
  • 2012 Springer
    Pisani, Margaret A.
  • 2014 Springer
    Factora, Ronan M.
    Increasingly, we hear of more and more elders falling victim to financial exploitation. Although this form of elder abuse has been recognized for years, its incidence, prevalence, and impact on the common individual has been only more recently brought to the spotlight. Despite these circumstances, recognition of risk factors and indicators of financial exploitation are not widely disseminated. Additionally, once situations are identified and confronted, the knowledge of what to do next is lacking. These gaps are present within the medical community, law-enforcement, and the finance community ? areas where opportunities for recognition and intervention are common. Our elders often have no idea of what to do when they see their own risk or when they fall victim. Aging and Money: Reducing Risk of Financial Exploitation and Protecting Financial Resources helps clinicians to integrate identification of such indicators of abuse into their geriatric assessment as well as guide them in performing an assessment of an individuals? financial decision-making capacity when appropriate. Aging and Money: Reducing Risk of Financial Exploitation and Protecting Financial Resources is an essential new text that provides the practicing clinician with information on identifying risk factors and clinical clues associated with financial exploitation and how to incorporate these steps into their practice.
  • 2008 Springer
    Marín-García, José; Goldenthal, Michael J.; Moe, Gordon W.
    Post-genomic view of aging: definition, theories and observations -- Overview of cardiovascular aging -- Molecular and cellular methodologies: a primer -- Molecular and cellular phenotypes of cardiovascular aging -- Aging of the vasculature and related systems -- Aging and the cardiovascular-related systems -- Cardiomyopathy and heart failure in aging -- Atherosclerosis, hypertension and aging -- Metabolic syndrome, diabetes and cardiometabolic risks in aging -- Gender and cardiovascular diseases in aging -- Cardiac dysrhythmias and channelopathies in aging -- Genetics of life span: lessons from model organisms -- Profiling the aging cardiovascular system: transcriptional, proteomic, SNPs, gene mapping and epigenetics analysis -- Translational research: gene, pharmacogenomics and cell-based therapy in the aging heart -- Nutrition and exercise in cardiovascular aging: metabolic and pharmacological interventions -- Aging and the frontier ahead.
  • 2010
    Eggleston, Karen; Tuljapurkar, Shripad.
    Status: Not Checked OutLane Catalog Record
    Preface / Michael Armacost -- Introduction / Karen Eggleston and Shripad Tuljapurkar -- Population aging and economic growth / David E. Bloom -- How demography shapes individual, social, and economic transitions in Asia / Shripad Tuljapurkar -- Changing intergenerational transfers in aging Japan / Naohiro Ogawa, Amonthep Chawla and Rikiya Matsukura -- Gender, migration, and the well-being of the elderly in rural China / Shuzhuo Li ... [et al.] -- Marriage and the elderly in China / Maria Porter -- Financing health care in a rapidly aging Japan / Naoki Ikegami -- Population aging and the introduction of long-term care insurance in South Korea / Soonman Kwon -- Old-age pension reform in South Korea / Byongho Tchoe -- The diabetes epidemic in the Asia-Pacific / Karen Eggleston ... [et al.] -- Families dealing with dementia : insights from mainland China, Hong Kong, and Taiwan / Dolores Gallagher-Thompson ... [et al.] -- Elderly care in Singapore : the state as last resort / Meng-kin Lim.
  • 2010 Springer
    Fay, Richard R.; Frisina, Robert D.; Gordon-Salant, Sandra; Popper, Arthur N.
  • 2010 Springer
    Tobin, Desmond John; Trüeb, Ralph M.
    Gerontobiology of the Hair Follicle / Desmond J. Tobin -- Molecular Basis of Androgenetic Alopecia / Valerie Anne Randall -- Inflammatory Phenomena and Fibrosis in Androgenetic Alopecia / Ralph M. Trüeb -- Post-Menopausal Frontal Fibrosing Alopecia / Steven Kossard -- Female Pattern Hair Loss / M. Javed Mohungoo and Andrew G. Messenger -- Hair Growth Parameters in Pre- and Postmenopausal Women / Paradi Mirmirani, Fangyi Luo, Scott R. Youngquist, Brian K. Fisher and James Li, et al. -- Comparative Histopathology of Androgenetic Alopecia, Diffuse Alopecia, and Senescent Alopecia / David A. Whiting -- Comparative Gene Expression Profiling of Senescent and Androgenetic Alopecia Using Microarray Analysis / Paradi Mirmirani and Pratima Karnik -- The Aging Hair Pigmentary Unit / Desmond J. Tobin -- Oxidative Stress Associated Melanocyte-Loss and Hair Growth Capacity in the Aging Hair Follicle: A Model for Tissue-Specific Aging / Eva M. J. Peters -- Human Hair Follicle Melanocytes as a Proxy Cell Type in Neurodegeneration Research / Nikolaos Papageorgiou, Elisabeth Carpenter and Desmond J. Tobin -- Effect of UV Radiation on Scalp and Hair Growth / Claudine Piérard-Franchimont, Pascale Quatresooz and Gérald E. Piérard -- Hair Photoaging / Won-Soo Lee -- Effect of Tobacco Smoking on Hair / Ralph M. Trüeb -- Age-Related General Problems Affecting the Condition of Hair / Ralph M. Trüeb -- Aging of Scalp and Age-Related Disorders of Scalp / Desmond Gan and Rodney Sinclair -- Care of Aging Hair and Photoprotection / Zoe Diana Draelos -- Possibilities and Limitations for Reversal of Age-Related Hair Loss / Nina Otberg, Isabel Restrepo and Jerry Shapiro -- Possibilities and Limitations for Reversal of Age-Related Pigment Loss / Ralph M. Trüeb -- Evidence-Based Hair Transplantation / Andreas M. Finner -- Future Directions: Gene Polymorphism Diagnostics Relevant to Hair / Justine A. Ellis -- Future Directions : The Known and Unknown Roles of Hair-Follicle Stem Cell Types / Robert M. Hoffman -- Future Directions: Bioengineering the Hair Follicle / Kurt S. Stenn, Ying Zheng and Jen-Chih Hsieh -- Hair After Death / Andrew S. Wilson and Desmond J. Tobin.
  • Siegel, Jacob S.
  • 2008 Springer
    Cameron, J. Stewart; Macias Nuñez, Juan F.; Oreopoulos, D. G.
  • 2012 Springer
    Breitenbach, Michael; Jazwinski, S. Michal; Laun, Peter (Cell biologist).
    Introduction -- Oxidative stresses and ageing -- The role of mitochondria in the aging processes of yeast -- The retrograde response and other pathways of interorganelle communication in yeast replicative aging -- Chronological aging in Saccharomyces cerevisiae -- Aging and the survival of quiescent and non-quiescent cells in yeast stationary-phase cultures -- Maximising the yeast chronological lifespan -- Amino acid homeostasis and chronological longevity in Saccharomyces cerevisiae -- DNA damage and DNA replication stress in yeast models of aging -- Yeast aging and apoptosis -- Cellular homeostasis in fungi: impact on the aging process -- Genome-wide analysis of yeast aging -- Genetic approaches to aging in budding and fission yeasts: new connections and new opportunities -- Evolution of asymmetric damage segregaton: a modelling approach -- Cellular ageing and the actin cyoskeleton.
  • 2006 Springer
    Lessenger, James E.
  • v. 1-2, 2006. Springer Protocols
    v. 2, 2006 Springer Protocols
    Wang, Kan.
  • 2015 Springer Protocols
    Fulltext v. 2 (2015) Springer Protocols
    Wang, Kan.
    Volume 1. Gateway®-compatible plant transformation vectors /Mark A. Smedley and Wendy A. Harwood -- Brachypodium distachyon /Jennifer N. Bragg ... [et al.] -- Medicago truncatula transformation using cotyledonary explants /Elane Wright and Zeng-Yu Wang -- Medicago truncatula transformation using leaf explants /Viviane Cosson, Alexis Eschstruth , and Pascal Ratet -- Setaria viridis /Joyce Van Eck and Kerry Swartwood -- Barley (Hordeum vulgare L.) transformation using immature embryos /Cornelia Marthe, Jochen Kumlehn, and Goetz Hensel -- Barley (Hordeum vulgare L.) transformation using embryogenic pollen cultures /Ingrid Otto, Andrea Müller, and Jochen Kumlehn -- Maize (Zea mays L.) /Bronwyn Frame ... [et al.] -- Maize, tropical (Zea mays L.) /Shireen K. Assem -- Finger millet [Eleusine coracana (L.) Gaertn.] /Stanislaus Antony Ceasar and Savarimuthu Ignacimuthu -- Oat (Avena sativa L.) /Sebastian Gasparis and Anna Nadolska-Orczyk -- Rice, indica (Oryza sativa L.) /Yukoh Hiei, Yuji Ishida, and Toshihiko Komari -- Rice, japonica (Oryza sativa L.) /Marcy Main, Bronwyn Frame, and Kan Wang -- Sorghum (sorghum bicolor ) /Xiaomei Guo, Zhengxiang Ge, Shirley J. Sato, and Tom E. Clemente -- Wheat (Triticum aestivum L.) transformation using immature embryos /Yuji Ishida ... [et al.] -- Wheat (Triticum aestivum L.) transformation using mature embryos /Eva Medvecká and Wendy A. Harwood -- Alfalfa (Medicago sativa L.) /Chunxiang Fu ... [et al.] -- Clovers (Trifolium spp.) /Samira Rahimi-Ashtiani ... [et al.] -- Clover, red (Trifolium pratense) /Michael L. Sullivan and Kenneth H. Quesenberry -- Cowpea [Vigna unguiculata (L.) walp.] /Ratikanta Behura ... [et al.] -- Lentil (Lens culinaris medik) /Ufuk Celikkol Akcay, Meral Yücel, and Hüseyin Avni Öktem -- Soybean [Glycine max (L.) Merr.] /Diane Luth, Katey Warnberg, and Kan Wang -- Brassica oleracea and B. napus /Penny A. C. Hundleby née Sparrow and Judith A. Irwin -- Cucumber (Cucumis sativus L.) and kabocha squash (Cucurbita moschata Duch) /Yoshihiko Nanasato and Yutaka Tabei -- Pepper, chili (Capsicum annuum) /Jung Min ... [et al.] -- Pepper, sweet (Capsicum annuum) /Iris Heidmann and Kim Boutilier -- Sugar beet (Beta vulgaris L.) /Hiroyo Kagami ... [et al.] -- Tomato (Solanum lycopersicum) /Dora Garcia, Javier Narváez-Vásquez, and Martha L. Orozco-Cárdenas.
  • 2007 Ovid
    Alpert, Joseph S.; Nixon, J. V.
  • 2011 Ovid
    Aurigemma, Gerard P.; Nixon, J. V.
  • 2010 Springer
    Zelek, Laurent; Zernik, Nicole.
  • 2012
    Harden, Victoria A.
    Status: Not Checked OutLane Catalog Record
    Society was not prepared in 1981 for the appearance of a new infectious disease, but we have since learned that emerging and reemerging diseases will continue to challenge humanity. This work is the first history of HIV/AIDS written for a general audience that emphasizes the medical response to the epidemic. The author, a medical historian approaches the AIDS virus from philosophical and intellectual perspectives in the history of medical science, discussing the process of scientific discovery, scientific evidence, and how laboratories found the cause of AIDS and developed therapeutic interventions. Furthermore, her book places AIDS as the first infectious disease to be recognized simultaneously worldwide as a single phenomenon. After years of believing that vaccines and antibiotics would keep deadly epidemics away, researchers, doctors, patients, and the public were forced to abandon the arrogant assumption that they had conquered infectious diseases. By presenting a discussion of the history of HIV/AIDS and analyzing how aspects of society advanced or hindered the response to the disease, the book illustrates how medicine identifies and evaluates new infectious diseases quickly and what political and cultural factors limit the medical community's response.
  • 2012 ebrary
    Nattrass, Nicoli.
    The conspiratorial move against HIV science and its consequences -- AIDS origin conspiracy theories in the United States and South Africa -- Who believes AIDS conspiracy theories and why leadership matters -- Science, politics, and credibility : David Gilbert fights AIDS conspiracy beliefs in US prisons -- Science, conspiracy theory, and the South African AIDS policy tragedy -- Hero scientists, cultropreneurs, living icons, and praise-singers : AIDS denialism as community -- Defending the imprimatur of science : Duesberg and the medical hypotheses saga -- The conspiratorial move and the struggle for evidence-based medicine.
  • 2014
    Halkitis, Perry N.
    30 years and counting -- The men of the AIDS generation -- Enter HIV -- Surviving AIDS -- And then middle age -- Resilience.
  • 2008 ClinicalKey
    Dolin, Raphael; Masur, Henry; Saag, Michael S.
    AIDS treatments continues to evolve. Now, so does the definitive reference on this complex and challenging subject. "AIDS Therapy, 3rd Edition" not only brings you comprehensive guidance on the latest treatments for HIV/AIDS and the full range of related disorders and syndromes, but also comes with access to updates online--so you can always tap into the most current therapy guidelines. Written by a "who's who" of leading global experts, the new edition of this classic reference is a must for any clinician who manages patients with HIV/AIDS. The most comprehensive coverage available on AIDS treatment equips you to meet any clinical challenge. Contributions from a large cast of noted international authorities put global "best practices" at your fingertips. Advice from some of the most respected experts in the field helps you manage your patients confidently.
  • v. 1, 1984
    Harrison, M. J.; Healy, T. E. J.; Thornton, J. A.
    Status: Not Checked OutLane Catalog Record
    pt. 1. The Basic sciences -- pt. 2. Clinical practice.
  • v. 1-3, 1881-82. Google Books
    Fulltext (v.2 1881) Google Books
    Fulltext (v.3 1882) Google Books
    Fothergill, J. Milner; Thorowgood, John C.
    pt. 1. Semeiology, specially designed for students preparing for examinations (1883 : 75 p.) -- pt. 2. Physical (1881 : [2], 61 p.) / J.C. Thorowgood -- pt. 3. What to ask (1882 : 66 p.).
  • 2007 Springer
    Meyers, C.
    Also available: Print – 2007
  • 2010 CRCnetBASE
    Gurjar, B. R.; Molina, Luisa T.; Molina, Mario J.; Ojha, C. Shekhar P.
  • 2016 Wellcome Trust
    Jones, Emma M.; Overy, Caroline; Tansey, E. M.
  • 2006 Springer
    Lacey, Maureen; West, Jon.
  • 2010
    Jiang, Ruoting; Hildemann, Lynn M.; Jacobson, Mark Z.; Ott, Wayne R.
    Exposure to secondhand smoke (SHS) has been associated with a number of health outcomes including cardiovascular diseases, pulmonary malfunction, lung cancer, and mortality. To protect public health, over 100 countries have adopted comprehensive or partial legislations against smoking. In the United States, California was the first state to enact a statewide ban on smoking in indoor workplaces in 1994. However, due to the sovereign nation status of California Indian tribes, smoking is still allowed and exposure to SHS continues in nearly all California Indian casinos. Fine particulate matter (PM2.5) is a major component of SHS pollution, and has been implicated as a risk factor for a range of chronic and acute diseases. The EPA's reference method for quantifying PM2.5 mass concentrations uses filter-based gravimetric samplers, which must be operated for many hours to collect enough sample. Since the gravimetric approach cannot measure short-term variations in PM2.5 levels, many personal exposure and environmental monitoring studies have employed real-time monitors for measuring PM2.5 concentrations. However, real-time monitors require proper calibration to accurately represent particle mass concentrations. This study characterized PM2.5 concentrations with real-time SidePak particle monitors in a large sample of California Indian casinos, spanning all sizes and distributed widely across the state. By comparing the SidePak measurements with the standard gravimetric method, we first calibrated the SidePak monitors for different types of aerosols commonly encountered indoors and outdoors, including SHS. We then modeled the response of SidePak monitors to SHS for a range of relative humidity levels. Finally, we designed a systematic casino monitoring protocol, using the calibrated real-time monitors, to examine PM2.5 concentrations in a field survey of 36 California Indian casinos and 8 Reno casinos.
  • 2013 WHO
    Also available: Print – 2013
  • 2009 CRCnetBASE
    Zaccone, Giacomo.
  • 2014 Springer
    Khan, Zahid Hussain.
    1. Physiology of the Airway / Yoo Kuen Chan -- 2. Airway Assessment: A Critical Appraisal / Zahid H. Khan -- 3. Videolaryngoscopy and Indirect Intubating Aids in Airway Management / Sze-Ying Thong and Wendy H. L. Teoh -- 4. Perioperative Care of Ambulatory Anaesthesia / Anil Agarwal and Kamal Kishore -- 5. The Paediatric Airway: Normal and Abnormal / Ina Ismiarti Shariffuddin and Lucy Chan -- 6. Intubation of the Pediatric Patient / Josef Holzki -- 7. The Difficult Pediatric Airway: Management Options / Mahesh Vakamudi -- 8. Perioperative Management of Obstructive Sleep Apnea / Karen Mak and Edwin Seet -- 9. Airway Management in Traumatic Brain Injury (TBI) / Fauzia Anis Khan -- 10. Airway Management in Cervical Spine Injured Patients / Srikanth Sridhar and Carin A. Hagberg -- 11. Indigenous Devices in Difficult Airway Management / Virendra K. Arya -- 12. Cricothyrotomy / Virendra K. Arya -- 13. Surgical Airway / Jinbin Zhang and Orlando Hung -- 14. Surgical Approaches to Airway Management / Surender K. Malhotra -- 15. Difficult Airway in Obstetrics / Sunanda Gupta and Apoorva Gupta -- 16. Ultrasonography: Heralding a New Era in Airway Management / Michael Seltz Kristensen and Wendy H. L. Teoh.
  • 2006 Springer
    Greene, Frederick L.
  • 2012 Springer
    Compton, Carolyn C.
  • 2010 STAT!Ref, Limited to 7 simultaneous users
    Edge, Stephen B.
    General information on cancer staging and end-results reporting -- Head and neck -- Digestive system -- Thorax -- Musculoskeletal sites -- Skin -- Breast -- Gynecologic sites -- Genitourinary sites -- Ophthalmic sites -- Central nervous system -- Lymphoid neoplasms -- Personnel and contributors.
  • 2008 ClinicalKey
    Albert, Daniel M.; Jakobiec, Frederick A.; Miller, Joan W.
    Genetics -- Immunology -- Microbiology -- Pharmacology and toxicology -- Principles of epidemiology -- Cornea and conjunctiva -- Refractive surgery -- Uveitis -- Lens -- Retina and vitreous -- Glaucoma -- Oculoplastics -- Ophthalmic pathology -- Neuro-ophthalmology -- Pediatric ophthalmology -- The eye and systemic disease -- Ocular oncology -- Trauma -- Optics -- Low vision -- Ethics and professionalism.
    Also available: Print – v. 1-4, 2008.
  • 2008 Springer Protocols
    Nagy, Laura E.
    Acute models of ethanol exposure to mice / Timothy P. Plackett and Elizabeth J. Kovacs -- A voluntary oral-feeding rat model for pathological alcoholic liver injury / George L. Tipoe ... [et al.] -- Intragastric ethanol infusion model in rodents / Hide Tsukamoto, Hasmik Mkrtchyan, and Alla Dynnyk -- A practical method of chronic ethanol administration in mice / Ruth A. Coleman ... [et al.] -- Analysis of ethanol developmental toxicity in zebrafish / Robert L. Tanguay and Mark J. Reimers -- The avian embryo in fetal alcohol research / Susan M. Smith -- Artificial rearing / Hector D. Dominguez and Jennifer D. Thomas -- Intragastric intubation of alcohol during the perinatal period / Sandra J. Kelly and Charles R. Lawrence -- Human monocytes, macrophages, and dendritic cells : alcohol treatment methods / Gyongyi Szabo and Pranoti Mandrekar -- Generation and use of primary rat cultures for studies of the effects of ethanol / Amanda Lindke, Barbara Tremper-Wells, and Michael W. Miller -- Development and properties of HepG2 cells that constitutively express CYP2E1 / Defeng Wu and Arthur I. Cederbaum -- Modeling the impact of alcohol on cortical development in a dish : strategies from mapping neural stem cell fate / Rajesh C. Miranda ... [et al.] -- Acetaldehyde-induced barrier disruption and paracellular permeability in Caco-2 cell monolayer / R.K. Rao -- Alcohol-induced oxidative stress in the liver : in vivo measurements / Gavin E. Arteel -- Isolation of Kupffer cells from rats fed chronic ethanol / Megan R. McMullen, Michele T. Pritchard, and Laura E. Nagy -- Dendritic cells in chronic in vivo ethanol exposure models / Kevin L. Legge and Annette J. Schlueter -- Formation and immunological properties of aldehyde-derived protein adducts following alcohol consumption / Geoffrey M. Thiele, Lynell W. Klassen, and Dean J. Tuma -- Assessment of natural killer (NK) and NKT cells in murine spleens and livers / Michael R. Shey and Zuhair K. Ballas -- Polyclonal and antigen-specific responses of T cells and T cell subsets / Betty M. Young ... [et al.] -- B-cell studies in chronic ethanol mice / Shilpi Verma ... [et al.] -- Histological analysis of bone / Urszula T. Iwaniec, Thomas J. Wronski, and Russell T. Turner -- Assessing effects of alcohol consumption on protein synthesis in striated muscles / Thomas C. Vary and Charles H. Lang -- Methods to investigate the effects of chronic ethanol on adipocytes / Becky M. Sebastian ... [et al.] -- Proteomic approaches to identify and characterize alterations to the mitochondrial proteome in alcoholic liver disease / Shannon M. Bailey ... [et al.] -- Alcoholic liver disease and the mitochondrial ribosome : methods of analysis / Alan Cahill and Peter Sykora -- Microarray analysis of ethanol-induced changes in gene expression / Robnet T. Kerns and Michael F. Miles.
  • 2011 Springer
    Guo, Q. Max; Vasiliou, Vasilis; Zakhari, Samir.
    The World Health Organization has identified chronic alcohol consumption as one of the top ten risk factors for worldwide burden of disease. The International Agency for Research on Cancer has identified alcohol as carcinogenic to humans, including cancers of the upper aerodigestive tract, colon, liver and breast. Alcohol{u2019}s actions may be direct e.g. effects on retinoic acid and one-carbon metabolism, or indirect, through metabolites such as acetaldehyde and reactive oxygen species or through various signaling pathways that influence cell cycle and apoptosis that may contribute to carcinogenesis. This volume reviews the state of the art in alcohol-related cancer research in ten chapters.
  • 1979/80.
    Norback, Judith.
    Status: Not Checked OutLane Catalog Record
  • 2012 Wiley
    Abraha, Iosief; Cusi, Cristina.
    Part 1. Alcohol. Psychosocial interventions -- Effectiveness of brief alcohol interventions in primary care populations -- Brief interventions for heavy alcohol users admitted to general hospital wards -- Alcoholics Anonymous and other 12-step programmes for alcohol dependence -- Mentoring adolescents to prevent substance use disorders -- Universal school-based prevention programmes for alcohol misuse in young people -- Universal multicomponent prevention programmes for alcohol misuse in young people -- Universal family-based prevention programmes for alcohol misuse in young people -- Social norms interventions to reduce alcohol misuse in university or college students -- Psychosocial interventions for women enrolled in alcohol treatment during pregnancy -- Pharmacological interventions -- Benzodiazepines for alcohol withdrawal -- Anticonvulsants for alcohol withdrawal -- Acamprosate for alcohol dependence -- Baclofen for alcohol withdrawal -- Gamma-hydroxybutyrate for treatment of alcohol withdrawal and prevention of relapse -- Psychotropic analgesic nitrous oxide for alcohol withdrawal -- Efficacy and safety of pharmacological interventions for the treatment of alcohol withdrawal -- Opioid antagonists for alcohol dependence -- Pharmacologic interventions for pregnant women enrolled in alcohol treatment. Part 2. Drugs. Psychosocial interventions -- School-based prevention for illicit substance use disorders -- Interventions for prevention of substance use disorders by young people delivered in non-school settings -- Case management for persons with substance use disorders -- Motivational interviewing for substance use disorders -- Therapeutic communities for substance use disorders -- Interventions for drug-using offenders in the courts, secure estabishments and the community -- Psychosocial interventions for pregnant women in outpatient illicit drug treatment programmes compared to other interventions -- Cocaine dependence -- Psychosocial interventions for cocaine and psychostimulant amphetamine related disorders -- Antidepressants for cocaine dependence -- Antipsychotic medications for cocaine dependence -- Anticonvulsants for cocaine dependence -- Dopamine agonists for cocaine dependence -- Disulfiram for the treatment of cocaine dependence -- Efficacy of psychostimulant drugs for cocaine dependence -- Auricular acupuncture for cocaine dependence -- Psychosocial treatment for opiate dependence -- Psychosocial and pharmacological treatments versus pharmacological treatments for opioid detoxification -- Psychosocial combined with agonist maintenance treatments versus agonist maintenance treatments alone for treatment of opioid dependence -- Alpha2-adrenergic agonists for the management of opioid withdrawal -- Buprenorphine for the management of opioid withdrawal -- Psychosocial treatment for opiate dependence -- Psychosocial and pharmacological treatments versus pharmacological treatments for opioid detoxification -- Psychosocial combined with agonist maintenance treatments versus agonist maintenance treatments alone for treatment of opioid dependence -- Alpha2-adrenergic agonists for the management of opioid withdrawal -- Buprenorphine for the management of opioid withdrawal -- Buprenorphine maintenance versus placebo or methadone maintenance for opioid dependence -- Methadone at tapered doses for the management of opioid withdrawal -- Methadone maintenance at different dosages for opioid dependence -- Methadone maintenance therapy versus no opioid replacement therapy for opioid dependence -- Opioid antagonists under heavy sedation or anaesthesia for opioid withdrawal -- Opioid antagonists with minimal sedation for opioid withdrawal -- Oral naltrexone maintenance treatment for opioid dependence -- Sustained-release naltrexone for opioid dependence -- Heroin maintenance for chronic heroin-dependent individuals -- LAAM maintainance verus methadone maintenance for heroin dependence -- Detoxification treatments for opiate-dependent adolescents -- Maintenance treatments for opiate-dependent adolescents -- Maintenance agonist treatment for opiate-dependent adolescents -- Maintenance agonist treatments for opiate-dependent pregnant women -- Pharmacological treatments for depression during opoid dependence -- Inpatient versus other setttings for detoxification for opiod dependence -- Psychotherapeutic interventions for cannabis use or dependence in outpatient settings -- Pharmacological interventions for benzodiazepine mono-dependence management in outpatient settings -- Treatment for amphetamine dependence -- Treatment for amphetamine withdrawal -- Treatment for amphetamine psychosis -- Treatment for methaqualone dependence in adults.
  • 2009
    Cherpitel, Cheryl J.
    Status: Not Checked OutLane Catalog Record
  • 2015 ScienceDirect
    Dasgupta, Amitava.
  • NIAAA
  • 2014 ScienceDirect
    Pfefferbaum, Adolf; Sullivan, Edith V.
    "Alcohol is the most widely used drug in the world, yet alcoholism remains a serious addiction affecting nearly 20 million Americans. Our current understanding of alcohol's effect on brain structure and related functional damage is being revolutionized by genetic research, basic neuroscience, brain imaging science, and systematic study of cognitive, sensory, and motor abilities. Volume 125 of the Handbook of Clinical Neurology is a comprehensive, in-depth treatise of studies on alcohol and the brain covering the basic understanding of alcohol's effect on the central nervous system, the diagnosis and treatment of alcoholism, and prospect for recovery. The chapters within will be of interest to clinical neurologists, neuropsychologists, and researchers in all facets and levels of the neuroscience of alcohol and alcoholism"--Publisher's description.
  • 2011 Springer
    Lesch, Otto-Michael.
  • 2007
    Gilvarry, Eilish; McArdle, Paul.
    Policy : the principles of service organization and practice / Paul McArdle and Eilish Gilvarry -- Determinants of substance misuse / Paul McArdle -- Drug use in young people : short-term effects and long-term harms / Dan Lubman, Yvonne Bonomo and Murat Yücel -- Young people, substances and harm / Mandy Abbott, Fariah Khan and Eilish Gilvarry -- Trends in substance use and abuse in young people / Cecilia A. Essau and Peter Wennberg -- Substance use and psychiatric comorbidity in children and adolescents / Michael Farrell -- The effectiveness of universal youth substance abuse prevention programmes / David R. Foxcroft, Debby Allen and Lindsey Coombes -- Prevention of substance abuse : targeted approaches / Paul McArdle -- Treatment : course and outcome / Eilish Gilvarry and Giles Hayden -- Legal and ethical issues in the treatment of children and young people / Sarah Woolrich -- Principles of assessment for adolescents with substance use disorders / Oscar G. Bukstein and Theresa Lutka-Fedor -- Assessment instruments and outcome measurement / Oscar G. Bukstein and Theresa Lutka-Fedor -- Biological markers (drugs) / Kim Wolff -- Assessement and management in the emergency department and the paediatric unit / Joan Robson -- Brief alcohol interventions in young people : evidence and applicability / Malathi Natarajan and Eileen Kaner -- Psychological interventions for young people with substance misuse disorders / Gillian Tober -- Empirical and clinical foundations of family-based interventions for adolescent substance abuse / Howard A. Liddle, Cynthia L. Rowe and Gayle A. Dakof -- Pharmacological treatment of adolescent substance use disorder / E. Jane Marshall and K.A.H. Mirza -- The role of primary care in management of substance use/abuse / Clare Gerada -- Integrated treatment of substance use disorders and co-occurring psychiatric disorders in adolescents / Robert D. Davies and Paula D. Riggs.
  • 2013 Springer
    Preedy, Victor R.; Watson, Ronald R.; Zibadi, Sherma.
    Part I. Overview and General Nutrition During Alcohol Use -- 1. Alcohol and Nutrition: An Overview / Francisco Santolaria and Emilio González-Reimers -- 2. Genetics of Alcohol Metabolism / Vijay A. Ramchandani -- 3. Laboratory Models Available to Study Alcohol and Nutrition / Nympha B. D'Souza EL-Guindy -- 4. Ethanol-Induced Lipid Peroxidation and Apoptosis in Embryopathy / Robert R. Miller Jr. -- 5. Alcohol Use During Lactation: Effects on the Mother-Infant Dyad / Julie A. Mennella -- Part II. Nutrients and Foods as Modified by Alcohol -- 6. Moderate Alcohol Administration: Oxidative Stress and Nutritional Status / Lorenzo Leggio, Anna Ferrulli, and Giovanni Addolorato -- 7. Alcohol Use and Abuse: Effects on Body Weight and Body Composition / Stefan Gazdzinski and Timothy C. Durazzo -- 8. Alcohol: Nutrition and Health Inequalities / Adrian Bonner and Margherita Grotzkyj-Giorgi -- 9. The Effect of Diet on Protein Modification by Ethanol Metabolites / Simon Worrall -- 10. Vitamin B12 De fi ciency in Alcoholics / Alberto Fragasso -- 11. American Indians/Alaskan Natives and Alcohol: Biology, Nutrition, and Positive Programs / Felina M. Cordova, Michael H. Trujillo, and Roger Dale Walker -- Part III. Nutrient Effects on Alcohol Metabolism -- 12. Metabolism of Ethanol to Acetaldehyde in the Rat Mammary Tissue: Inhibitory Effects of Plant Polyphenols and Folic Acid / Gerardo Daniel Castro and José Albe -- 13. Dietary Zinc Supplementation and Prenatal Ethanol Exposure / Peter Coyle, Brooke Summers-Pearce, Carina J. Cowley, and Allan M. Rofe -- 14. Tocotrienol and Cognitive Dysfunction Induced by Alcohol / Kanwaljit Chopra and Vinod Tiwari -- 15. Soy Products Affecting Alcohol Absorption and Metabolism / Mitsuyoshi Kano and Norihiro Kubota -- 16. Oats Supplementation and Alcohol-Induced Oxidative Tissue Damage / Christopher B. Forsyth, Yueming Tang, Robin M. Voigt, Turan Rai, and Ali Keshavarzian -- 17. Fish Oil n-3 Fatty Acids to Prevent Hippocampus and Cognitive Dysfunction in Experimental Alcoholism / Nataliya A. Babenko -- 18. Alcohol in HIV and Possible Interactions with Antiretroviral Medications / Marianna K. Baum, Sabrina Sales-Martinez, and Adriana Campa -- Part IV. Alcohol Interactions with Foods -- 19. Popular Energy Drinks and Alcohol / Erin C. Duchan -- 20. The Psychological Synergistic Effects of Alcohol and Caffeine / Ambereen Ameer and Ronald Ross Watson -- 21. Alcohol and Smoking: A Correlation of Use in Youth? / Meghan Denning and Ronald Ross Watson -- 22. Are There Physiological Correlations Between Alcohol and Tobacco Use in Adults? / Cynthia Lee and Ronald Ross Watson -- 23. Alcohol, HIV/AIDS, and Liver Disease / Tamsin A. Knox, Logan Jerger, and Alice M. Tang -- Part V. Alcohol and Chronic Diseases -- 24. Nutritional Status, Socioeconomic Factors, Alcohol, and Cataracts / Vaishali Agte and Kirtan V. Tarwadi -- 25. Alcohol Intake and High Blood Pressure / Amy Z. Fan and Yueren Zhou -- 26. Alcohol and Dyslipidemia / Indrajit Chowdhury -- 27. Dietary Antioxidants in Chronic Alcoholic Pancreatitis / Mirosław Jarosz and Ewa Rychlik -- 28. Alcohol Consumption, Lifestyle Factors, and Type 2 Diabetes / Martin D. Stricker, Henk F.J. Hendriks, and Joline W.J. Beulens -- 29. Alcohol, Overweight and Obesity / Sasiwarang Goya Wannamet -- 30. Nutrition: Alcohol and Anorectic and Bulimic Adolescents / Konstantina Magklara -- 31. Viral Infections and Cancer During Alcohol Use / Malgorzata Schlegel-Zawadzka -- Part VI. Cancer as Modified and Induced by Alcohol -- 32. Ethanol and Hepatocarcinogenesis / Helmut K. Seitz and Felix Stickel -- 33. Alcohol, Diet, and Their Interaction in Colorectal and Urinary Tract Tumors / María Marta Andreatta , Aldo R. Eynard, and Alicia Navarro -- 34. Alcohol, Acetaldehyde, and Digestive Tract Cancer / Satu Väkeväinen and Mikko Salaspuro -- 35. Alcohol Intake and Esophageal Cancer: Epidemiologic Evidence / Jill Layton and Jianjun Zhang -- Part VII. Alcohol and Liver Diseases -- 36. A Nutritional Approach to Prevent Alcoholic Liver Disease / Samuel William French -- 37. Nutraceutical Potential of Indigenous Plant Foods and Herbs for Treatment of Alcohol-Related Liver Damage / Vaishali Agte and Upendra Raghunath Gumaste -- 38. Alcohol and Nutrition as Risk Factors for Chronic Liver Disease / Stefano Bellentani, Claudio Tiribelli, and Giorgio Bedogni -- 39. Alcohol-Related Liver Disease: Roles of Insulin Resistance, Lipotoxic Ceramide Accumulation, and Endoplasmic Reticulum Stress / Suzanne M. de la Monte -- 40. Nutrition and Alcoholic and Nonalcoholic Fatty Liver Disease: The Significance of Cholesterol / Munechika Enjoji , Kenichiro Yasutake, Motoyuki Kohjima, and Makoto Nakamuta -- 41. Dietary Fatty Acids and Alcoholic Liver Disease / Takayo Kawakami, Yasuko Murakami, and Misako Okita -- 42. Nutrition in Alcoholic Steatohepatitis / Juan Caballeria, Javier Michelena, and Jose Altamirano -- 43. Alcoholic and Nonalcoholic Fatty Liver Disease and Vitamin A / Gabriela Villaça Chaves and Wilza Arantes.
  • 2014 Springer
    Guidot, David M.; Mehta, Ashish J.
    Alcohol Use Disorders and the Lung: A Clinical and Pathophysiological Approach is an excellent resource for clinicians who care for individuals affected by alcohol use disorders in diverse settings. Although alcohol abuse alone does not cause acute lung injury, it renders the lung susceptible to dysfunction in response to the inflammatory stresses of sepsis, trauma, and other clinical conditions recognized to cause acute lung injury. In parallel, these same pathophysiological effects of alcohol abuse significantly increase the risk of a wide range of serious lung infections. Many clinicians involved in the primary treatment of alcohol use disorders, such as addiction psychiatrists, will find this text of interest as it will expand their understanding of the health consequences of alcohol use disorders. In parallel, clinicians who specialize in pulmonary and/or critical care medicine will have a unique resource that provides a comprehensive review of the pathophysiology of alcohol-related lung disorders and insights into evolving therapeutic options in these vulnerable individuals. Alcohol Use Disorders and the Lung: A Clinical and Pathophysiological Approach fills a gap in the literature and presents the evolving clinical research that may soon lead to novel therapies that can improve lung health in individuals with alcohol use disorders and co-existing conditions such as HIV infection.
  • 2016 Springer
    Chalasani, Naga; Szabo, Gyongyi.
  • Google Books
    v. 1. Final report -- v. 2. Alcohol abuse and alcoholism -- v. 4. Summary of Federal and state alcoholism programs.
    Also available: Print – v. 1, 1974.
  • 2009 Springer
    Hoessler, Jérôme.
  • 2014 Springer
    Constine, Louis S.; Marks, Lawrence B.; Rubin, Philip.
    The literature on the late effects of cancer treatment is widely scattered in different journals since all major organ systems are affected and management is based on a variety of medical and surgical treatments. The aim of ALERT Adverse Late Effects of Cancer Treatment is to offer a coherent multidisciplinary approach to the care of cancer survivors. The central paradigm is that cytotoxic multimodal therapy results in a perpetual cascade of events that affects each major organ system differently and is expressed continually over time. Essentially, radiation and chemotherapy are intense biologic modifiers that allow for cancer cure and cancer survivorship but accelerate senescence of normal tissues and increase the incidence of age-related diseases and second malignant tumors. Volume 1 of this two-volume work focuses on the general concepts and principles relevant to late effects and on the dynamic interplay of molecular, cytologic and histopathologic events that lead to altered physiologic and metabolic functions and their clinical manifestations. Chapters are also included on legal issues, economic aspects, nursing, psychological issues and quality of life.
  • 2014 Springer
    Constine, Louis S.; Marks, Lawrence B.; Rubin, Philip.
    The literature on the late effects of cancer treatment is widely scattered in different journals since all major organ systems are affected and management is based on a variety of medical and surgical treatments. The aim of ALERT Adverse Late Effects of Cancer Treatment is to offer a coherent multidisciplinary approach to the care of cancer survivors. The central paradigm is that cytotoxic multimodal therapy results in a perpetual cascade of events that affects each major organ system differently and is expressed continually over time. Essentially, radiation and chemotherapy are intense biologic modifiers that allow for cancer cure and cancer survivorship but accelerate senescence of normal tissues and increase the incidence of age-related diseases and second malignant tumors. Volume 2 of this two-volume work comprehensively documents potential late effects in all the normal tissue anatomic sites in the human body. The detection, diagnosis, management and prevention of effects are all considered in detail, and prognostic outcomes are discussed. Radiation risk factors and interactions with chemotherapy effects are clearly presented. The text is accompanied by numerous supportive illustrations and tables.
  • 2014 Springer
    Leff, Alexander; Starrfelt, Randi.
    This book is a comprehensive review of the main acquired disorders of reading: hemianopic, pure and central alexia. The authors review the diagnostic criteria for each of the different types of disorder, and the efficacy of the therapeutic studies that have attempted to remediate them. The different theoretical models of adult reading, which largely rest on how the reading system responds to injury, are also discussed and evaluated. Focal brain injury caused by stroke and brain tumors are discussed in depth as are the effects of dementia on reading. This book starts with a chapter on normal reading, followed by chapters on hemianopic alexia, pure alexia and central alexia, each structured in the same way, with: a description of the condition; a historical review of cases to date; psychophysics; consideration of the causative lesions; evidence from functional imaging studies on patients and, most importantly, a review of the evidence base for treating each condition. Finally, there is a chapter on how patient data has informed how we think about reading.
  • 2007 Springer
    Seckbach, J.
  • 2009 Springer
    Rehm, Bernd.
  • 2012
    Ryckman, Raymond Albert; Kuhl, Ellen; Lew, Adrian; Pinsky, P.
    In this work we present a series of scientific contributions made to the study of the impact of projectiles into tissue-like materials, specifically the synthetic artificial tissue simulant Perma-Gel. These contributions consist of a combination of experimental observations, algorithmic ideas and numerical tools which demonstrate a series of problems and solutions to trying to simulate nearly incompressible soft tissues using finite elements. A number of experiments were performed by taking high-speed footage of the firing of spherical steel bullets at different speeds into Perma-Gel, a new thermoplastic material used as a proxy to human muscle tissue. This work appears to be the first publicly released experimental work using Perma-Gel and is part of the small amount of non-classified work looking at ballistic gelatin behavior. A number of experimental observations were made regarding the material behavior, elastic and plastic deformation around the projectile, and the possibility of cavitation. This work introduces an explicit dynamic contact algorithm that takes advantage of the asynchronous time stepping nature of Asynchronous Variational Integrators (AVI) to improve performance when simulating elastic-body rigid-wall contact. We demonstrate a number of desirable properties over traditional one-time-step methods for the simulation of solid dynamics and provide a number of examples highlighting the advantages of this method. The explicit contact algorithm and AVI was used to simulate the impact of a projectile into a simulated block of gelatin, but was hindered by difficulties using the realistic material parameters. Using a parallelized version of the algorithm, large-scale simulations were performed for progressively smaller shear moduli. As the simulations approached realistic values for the shear modulus, unstable element configurations formed which required infeasibly small time steps to successfully resolve. The behavior observed for the shear moduli we could numerically simulate with did not resemble the experimental results. To simulate with smaller values, we had to go to an axisymmetric setting. The axisymmetric setting increased the range of shear moduli which could be simulated and demonstrated the same dynamic behavior, though the issue of unstable element configurations continued to occur in extreme cases. To deal with the issue of unstable elements, we created an axisymmetric remeshing strategy to compensate for the unstable element configurations and insufficient spatial resolution. This strategy consists of periodically applying a remeshing and transfer algorithm that updates highly deformed finite element meshes with configurations formed with elements having uniform aspect ratios and local refinement in important areas. The axisymmetric setting with remeshing increased the range of potential shear modulus values that could be simulated. This allowed for the identification of qualitative similarities in the transient behavior between the numerical results and the experimental footage.
  • 2009
    Davydov, Eugene V.; Batzoglou, Serafim; Dill, David; Sidow, Arend.
    Availability of massive amounts of genomic data from hundreds of species has introduced many challenging computational problems as well as the need for efficient algorithmic tools that leverage multiple species information to facilitate biological analysis. This dissertation discusses two such problems: noncoding RNA multiple structural alignment and constrained element detection. Noncoding RNA genes (ncRNAs) are regions of the genome that are transcribed but not translated into protein, and fold directly into secondary and tertiary structures which can have a variety of important biological functions. Because their function depends closely on the secondary structure, ncRNAs often do not exhibit enough primary sequence conservation to be properly aligned using standard sequence-based methods. I therefore consider the problem of RNA multiple structural alignment, i.e., performing sequence alignment and secondary structure prediction simultaneously. In the first part of this dissertation I introduce a novel graph theoretic framework for analyzing this problem and prove that when the number of sequences is not fixed it is NP-complete. I also provide a polynomial time algorithm that approximates the optimal solution to within a factor of O(log^2 n). Constrained elements are regions of the human genome exhibiting evidence of purifying selection and therefore biological function. Computational identification of such elements is one of the major goals of comparative genomics. In the second part of this dissertation I present GERP++, a new tool for efficient constrained element detection that significantly improves on one of the current leading methods, GERP. While retaining GERP's biological transparency and metric for quantifying position-specific constraint, GERP++ uses a more rigorous method for computing evolutionary rates and a novel algorithm for element identification that uses statistical significance directly to evaluate and rank candidate elements. These algorithmic improvements decrease the running time by several orders of magnitude in practice, enabling high-throughput analysis of large data sets. Furthermore, I present analysis and biological interpretation of constrained elements identified by GERP++ in the human genome from recently available multiple species alignments.
  • Heineman, George T.; Pollice, Gary; Selkow, Stanley.
  • Savas, Berkant.
  • 2007 Springer
    Fujii, Tateo; Goto, Keiichi; Yokota, Akira.
  • 2015
    Richardson, Liz.
    Recent initiatives have sought to close gaps between the two federal agencies' medical technology evaluation processes.
  • 2010
    Amat Gil, Fernando; Downing, Kenneth; Horowitz, Mark; Koller, Daphne.
    Cryo-Electron tomography (CET) is the only imaging technology capable of visualizing the 3D organization of intact bacterial whole cells at nanometer resolution in situ. However, quantitative image analysis of CET datasets is extremely challenging due to very low signal to noise ratio (well below 0dB), missing data and heterogeneity of biological structures. In this thesis, we present a probabilistic framework to align CET images in order to improve resolution and create structural models of different biological structures. The alignment problem of 2D and 3D CET images is cast as a Markov Random Field (MRF), where each node in the graph represents a landmark in the image. We connect pairs of nodes based on local spatial correlations and we find the "best'' correspondence between the two graphs. In this correspondence problem, the "best'' solution maximizes the probability score in the MRF. This probability is the product of singleton potentials that measure image similarity between nodes and the pairwise potentials that measure deformations between edges. Well-known approximate inference algorithms such as Loopy Belief Propagation (LBP) are used to obtain the "best'' solution. We present results in two specific applications: automatic alignment of tilt series using fiducial markers and subtomogram alignment. In the first case we present RAPTOR, which is being used in several labs to enable real high-throughput tomography. In the second case our approach is able to reach the contrast transfer function limit in low SNR samples from whole cells as well as revealing atomic resolution details invisible to the naked eye through nanogold labeling.
  • 2016 NLM
  • 2006 Springer
    Horikoshi, Kōki.
  • Google Books
    Schmidt, Julius.
    Also available: Print – 1908-11.
  • 2015 Springer
    Rovenský, Jozef.
    This book comprehensively describes alkaptonuria and ochronosis. Beginning with the history, genetics, pathophysiology and diagnostics of the disease, the authors subsequently present a detailed characterization of its clinical manifestation in the spine, peripheral joints, eyes, ears, visceral organs and respiratory tract, its pathological anatomy and histology, as well as differential diagnosis. This is complemented by the latest data on therapy and experimental models of alkaptonuria, and supported by several case reports. Numerous pictures and radiological images document the clinical symptoms, giving the reader a solid understanding of the disease. On the basis of the editor?s and authors? own extensive observations, the book offers an analysis of protein metabolism and aromatic amino acids in the context of alkaptonuria. Written by international experts in the field, the book offers a valuable reference guide for healthcare professionals working in rheumatology, dermatology, pulmonology, otolaryngology and histopathology.
  • v. 1-<15>, 1673/76F-<1704/07F>.
    Leeuwenhoek, Antoni van; Rijnberk, Gérard van.
    Status: Not Checked OutLane Catalog Record
    v 1. 1673-1676 -- v. 2. 1676-1679 -- v. 3. 1679-1682 -- v. 4. 1683-1684 -- v. 5. 1685-1686 -- v. 6. 1686-1687 -- v. 7. 1687-1688 -- v. 8. 1688-1692 -- v. 9. 1692-1694 -- v. 10. 1694-1695 -- v. 11. 1695-1696 -- v. 12. 1696-1699 -- v. 13. 1700-1701 -- v. 14. 1701-1704 -- v. 15. 1704-1707.
  • 2006 Springer
    Inderjit; Mukerji, K. G.
  • 2006 Springer
    González, Luís; Pedrol, Nuria; Reigosa Roger, Manuel Joaquín.
    General -- Methodological aspects -- Physiological aspects of allelopathy -- Ecophysiology and allelopathy -- Ecological aspects of allelopathy -- Allelopathy in different environments -- Applied aspects of allelopathy.
  • 2009 Springer
    Aimar, Elena; Schindler, Antonio; Vernero, Irene.
  • 2015 Springer
    Pokorski, Mieczyslaw.
    Respiratory allergy is constantly encountered and is sharply on the rise, particularly in the two most vulnerable age-groups: young children and seniors. Allergy results in airway hyperactivity and increased airway resistance, with all inflammatory sequelae being ensued. The chapters show how respiratory allergy research is interconnected with other disciplines by discussing neurotransmitter, membrane receptor, and ionic channel mechanisms of allergy and by giving diagnostic and pharmacological cues on desensitization and therapy.
    Also available: Print – 2015
  • 2007 Springer
    Anderson, John A.; Lieberman, Phil L.
    Allergic disease: pathophysiology and immunopathology -- Approach to the allergic patient -- Diagnostic tests in allergy -- Environmental allergens -- Anaphylaxis -- Insect sting allergy -- The child with asthma -- Asthma in adults: diagnosis and management -- Allergic rhinitis: diagnosis and treatment -- Sinusitis and otitis media -- Diagnosis and treatment of ocular allergy -- Urticaria and angioedema -- Atopic dermatitis -- Contact dermatitis and other contact reactions -- Food allergy and intolerance -- Allergic and allergic-like reactions to drugs and other therapeutic agents -- Antihistamines -- β-adrenergic agonists -- Theophylline -- Antileukotriene agents in the management of asthma -- Cromolyn and nedocromil: nonsteroidal anti-inflammatory therapy for asthma and other allergic diseases -- Anticholinergic agents in respiratory diseases -- Glucocorticoid therapy in asthma -- Anti-IgE therapy -- Environmental control of respiratory indoor allergens -- Allergen immunotherapy -- Controversies in allergy and allergy-like diseases -- The patient with 'too many infections'.
  • v. 1-2, 2008.
    Bousquet, Jean; Holt, Patrick G.; Kaplan, Allen P.; Kay, A. B.
    Status: Not Checked OutLane Catalog Record
  • 2006 Karger
    Crameri, Reto.
    Also available: Print – 2006
  • 2012 Karger
    Bienenstock, John.
    Relations between asthma and psychological distress: an old idea revisited -- Brain and asthma: what are the linkages? -- Stress-related programming of autonomic imbalance: role in allergy and asthma -- Role of parasympathetic nerves and muscarinic receptors in allergy and asthma -- Developmental programming of allergic diseases -- Mind-body interrelationship in DNA methylation -- Neurotrophins in chronic allergic airway inflammation and remodeling -- Pathways underlying afferent signaling of bronchopulmonary immune activation to the central nervous system -- Allergen-induced neuromodulation in the respiratory tract -- Role of microbiome in regulating the HPA axisd and its relevance to allergy -- Autonomic regulation of anti-inflammatory activities from salivary glands -- Mast cell-nerve functional unit: a key component of physiologic and pathophysiologic responses -- Neural and behavioral correlates of food allergy -- Neuroendocrine-immune connection regulates chronic inflammatory disease in allergy -- Itch and the brain.
  • 2015 Springer
    Raz, E.; Tao, Ailin.
    Allergic Disease Epidemiology -- The Pathogenesis of Allergy: A Brief Introduction -- Genetics and Epigenetic Regulation in Allergic Diseases -- Cross-Reactivity -- From Allergen Extracts to Allergen Genes and Allergen Molecules -- Allergen Gene Cloning -- High Throughput Screening of Allergy -- Surrogate Markers for Allergen-Specific Immunotherapy -- Immune Responses to Allergens in Atopic Disease: Considerations for Bioinformatics -- Antigenicity, Immunogenicity and Allergenicity -- Bioinformatic Classifiers for Allergen Sequence Discrimination -- Strategies for the Modification and Evaluation of Allergenicity -- Bioinformatics Methods to Predict Allergen Epitopes -- Allergen Database.
  • v. 1-6, 2009-2010. Springer
    v. 2, 2009 Springer
    v. 3, 2009 Springer
    v. 4, 2009 Springer
    v. 5, 2010 Springer
    v. 6, 2010 Springer
    Holgate, S. T.; Pawankar, Ruby; Rosenwasser, Lanny J.
    v. 1. Epigenetics, allergens and risk factors -- v. 2. Classification and pathomechanisms -- v. 3. Clinical manifestations -- v. 4. Diagnosis and health economics -- v. 5. Therapy and prevention -- v. 6. Future perspectives.
  • 2008 Springer Protocols
    Jones, Meinir G.; Lympany, Penny.
    Understanding of the molecular mechanisms of allergy / Meinir Jones -- T cell : primary culture from peripheral blood / Monika Raulf-Heimsoth -- Production of T-cell lines / Helga Kahlert -- Production of human T-cell clones / Adrienne Verhoef -- Mapping of human T-cell epitopes of allergens / Thomas Zeiler and Tuomas Virtanen -- Determining MHC restriction of T-cell responses / Mark Larché -- Short-term culture of CD8 cells and intracellular cytokine staining / Beejal Vyas and Alistair Noble -- Isolation, flow cytometric analysis, and suppression assay of CD4+ CD25+ T-regulatory cells / Hayley Jeal -- Monocyte-derived dendritic cells as antigen-presenting cells in T-cell proliferation and cytokine production / Sun-sang J. Sung -- Ultrasensitive ELISA for measurement of human cytokine responses in primary culture / William P. Stefura ... [et al.] -- Quantification of human chemokine production in TLR-stimulated and antigen-specific recall responses / Monique Stinson ... [et al.] -- Standardization of allergen extracts / Jørgen Nedergaard Larsen and Sten Dreborg -- Immunoelectrophoresis for the characterization of allergen extracts / Gitte Nordskov Hansen and Jørgen Nedergaard Larsen -- Conjugation of haptens / Ranulfo Lemus and Meryl H. Karol -- Monoclonal antibodies / Helga Kahlert and Oliver Cromwell -- Purification of antibodies / Per H. Larsson -- Collection of air samples to quantify exposure to airborne allergens / Susan Gordon -- Assay of air sample eluates / Anne Renström and Susan Gordon -- The halogen assay : a new technique for measuring airborne allergen / Euan Tovey ... [et al.] -- Measurement of specific IgG anti-Fel d 1 antibodies / Meinir G. Jones -- The facilitated antigen binding (FAB) assay : a protocol to measure allergen-specific inhibitory antibody activity / James N. Francis -- Microscopic identification and purity determination of pollen grains / Magdalena Rahl -- Biopanning for the characterization of allergen mimotopes / Isabella Pali-Schöll and Erika Jensen-Jarolim -- Identification of mast cells and mast cell subpopulations / Mark Buckley and Andrew F. Walls -- Purification and characterization of mast cell tryptase and chymase from human tissues / Alan R. McEuen and Andrew F. Walls -- Experimental activation of mast cells and their pharmacological modulation / Shaoheng He and Andrew F. Walls -- In situ hybridization / Kayhan T. Nouri-Aria.
  • 2012 ScienceDirect
    2011 ClinicalKey
    Broide, David H.; Church, Martin; Holgate, S. T.; Martinez, Fernando D.
    The new edition of Allergy, by Drs. Stephen Holgate, Martin Church, David Broide, and Fernando Martinez, uses an enhanced clinical focus to provide the clear, accessible guidance you need to treat allergy patients. A more consistent format throughout features new differential diagnosis and treatment algorithms, updated therapeutic drug information in each chapter, and additional coverage of pediatric allergies. With current discussions of asthma, allergens, pollutants, drug treatment, and more, as well as access to the full text and illustrations online at www.expertconsult.com, this comprehensive resource is ideal for any non-specialist who treats patients with allergies. Prescribe appropriate therapies and effectively manage patients' allergies using detailed treatment protocols. Identify allergic conditions quickly and easily with algorithms that provide at-a-glance assistance. Explore topics in greater detail using extensive references to key literature.
  • Google Books
    Lubarsch, Otto.
    Also available: Print – v. 1, 1905.
  • v. 1, 1916-24.
    Tschermak-Seysenegg, Armin von.
    Status: Not Checked OutLane Catalog Record
    Bd. 1. Groundlagen der allgemeinen Physiologie. T. 1. Allgemeine Charakteristik des Lebens physikalische und chemische Beschaffenheit der lebenden Substanz.
  • v. 1-3, 5, 7, 10, 1927-40.
    Kirschner, Martin.
    Status: Not Checked OutLane Catalog Record
  • v. 5, 1953.
    Guleke, N.; Zenker, Rudolf; Kirschner, Martin.
    Status: Not Checked OutLane Catalog Record
    Bd. 1. Allgemeine Operations lehre / Gerd Hegemann -- Bd. 2. Die Eingriffe am Gehirnschädel, Gehirn an der Wirbelsäule und am Rückenmark / N. Guleke -- Bd. 4. Gesicht/Gesichtsschädel Kiefer -- Bd. 5. Die Oto-Rhino-Laryngologischen operationen / H.J. Denecke -- Bd. 6, T.1. Die Eingriffe an der Brust und in der Brusthöhle / Alfred Brunner -- Bd. 7, T. 1. Die Eingriffe in der Bauchhöhle / Martin Kirschner -- Bd. 7, T. 2. Die Eingriffe bei den Bauchbüchen / Martin Kirschner -- Bd. 8. Die Eingriffe an den Harnorganen Nebennieren und männlichen Geschlechtsorganen / Leonhard Lurz -- Bd. 9 Gynäkologische Operationen / K.G. Ober [und] H. Meinrenken -- Bd. 10. Die Operationen an den Extremitäten / Werner Wachsmuth.
  • v. 1-[2], 1919-[1926]. Google Books
    Kraus, Friedrich.
    v. 1. Allgemeiner Teil -- v. 2. Besonderer Teil, I. Tiefenperson.
  • 2010 Springer
    Laughlin, Mary J.; Lazarus, Hillard M.
  • 2006 CRCnetBASE
    Bowery, N. G.
  • 2008 Springer
    Traut, Thomas.
    Section 1. Overview of enzymes. Introduction to enzymes ; The limits for life define the limits for enzymes ; Enzyme kinetics ; Properties and evolution of allosteric enzymes ; Kinetics of allosteric enzymes -- Section 2. K-type enzymes. Hemoglobin ; Glycogen phosphorylase ; Phosphofructokinase ; Ribonucleotide reductase ; Hexokinase -- Section 3. V-type enzymes. Introduction to V-type enzymes ; G proteins ; Protein kinases.
  • 2012 Springer Protocols
    Fenton, Aron W.
    Binding techniques to study the allosteric energy cycle -- Kinetic trapping of a key hemoglobin intermediate -- Allosteric coupling between transition metal-binding sites in homooligomeric metal sensor proteins -- Studying the allosteric energy cycle by isothermal titration calorimetry -- Detecting "Silent" Allosteric coupling -- Using mutant cycle analysis to elucidate long-range functional coupling in allosteric receptors -- A review of methods used for identifying structural changes in a large protein complex -- Allosteric mechanisms of g protein-coupled receptor signaling: A structural perspective -- Dynamic light scattering to study allosteric regulation -- Dissecting the linkage between transcription factor self-assembly and site-specific DNA binding: The role of the analytical ultracentrifuge -- Fluorescence correlation spectroscopy and allostery: The case of GroEL -- The morpheein model of allostery: Evaluating proteins as potential morpheeins -- Combining NMR and molecular dynamics studies for insights into the allostery of small GTPase-protein interactions -- Hydrogen-deuterium exchange study of an allosteric energy cycle -- Ensemble properties of network rigidity reveal allosteric mechanisms -- An in vivo approach to isolating allosteric pathways using hybrid multimeric proteins -- Mutations in the GABA(A) receptor that mimic the allosteric ligand etomidate -- Allosteric regulation of human liver pyruvate kinase by peptides that mimic the phosphorylated/dephosphorylated N-terminus -- In silico-screening approaches for lead generation: Identification of novel allosteric modulators of human-erythrocyte pyruvate kinase -- Identification of allosteric-activating drug leads for human liver pyruvate kinase -- A critical evaluation of correlated mutation algorithms and coevolution within allosteric mechanisms -- The advantage of global fitting of data involving complex linked reactions -- Predicting binding sites by analyzing allosteric effects.
  • 2011 Thieme eNeurosurgery
    Al-Mefty, Ossama; DeMonte, Franco; McDermott, Michael W.
    "This new edition of Meningiomas proves a valuable contribution to the literature on the fascinating aspects of meningioma biology, diagnosis, and management"--Provided by publisher.
  • 2015 Karger
    Ioannides, Dimitrios; Tosti, Antonella.
    Normal and aging hair biology and structure 'aging and hair' -- Evaluation of hair loss -- Scalp dermoscopy or trichoscopy -- Androgenetic, diffuse and senescent alopecia in men: practical evaluation and management -- Female pattern hair loss -- Hair loss in children -- Alopecia areata -- Primary scarring alopecias -- Molecular genetics of alopecias -- Alopecias due to drugs and other skin and systemic disorders -- Effect of ultraviolet radiation, smoking and nutrition on hair -- Hair care and dyeing -- Age-related hair pigment loss -- Ethnic hair disorders -- Advances in hair transplantation: longitudinal partial follicular unit transplantation.
  • 2016 Springer
    Sandhaus, Robert A.; Wanner, Adam.
    Alpha-1- Antitrypsin and the Serpins -- Alpha-1 Antitrypsin: The protein -- Misfolding and Polymerisation of Alpha1-Antitrypsin ? Conformational Pathology and Therapeutic Targeting -- Managing the Adaptive Proteostatic Landscape: Restoring Resilience in Alpha-1 Antitrypsin Deficiency -- United States Targeted Detection Program for Alpha-1 Antitrypsin Deficiency -- Lung Disease of Alpha-1 Antitrypsin Deficiency -- Alpha-1-Antitrypsin Deficiency: Role in Health and Disease -- Alpha-1 Antitrypsin as a Therapeutic Agents for Conditions not Associated with Alpha-1 Antitrypsin Deficiency -- The Alpha-1 Constellation of Voluntary Health Organizations as a Paradigm for Confronting Other Rare Diseases.
  • 2006
    Sandri-Goldin, Rozanne M.
    Status: Not Checked OutLane Catalog Record
  • Everett, Nicholas.
    The Alphabet of Galen is a critical edition and English translation of a text describing, in alphabetical order, nearly three hundred natural products - including metals, aromatics, animal materials, and herbs - and their medicinal uses. A Latin translation of earlier Greek writings on pharmacy that have not survived, it circulated among collections of 'authorities' on medicine, including Hippocrates, Galen of Pergamun, Soranus, and Ps. Apuleius. This work presents interesting linguistic features, including otherwise unattested Greek and Latin technical terms and unique pharmacological descriptions. Nicholas Everett provides a window onto the medieval translation of ancient science and medieval conceptions of pharmacy. With a comprehensive scholarly apparatus and a contextual introduction, The Alphabet of Galen is a major resource for understanding the richness and diversity of medical history.
  • 2011
    Valenzuela, Ricardo Andres; Goodman, Miriam Beth; Huguenard, John R.; MacIver, M. Bruce; Madison, Daniel V.
    Down Syndrome and Fragile X Syndrome are disorders of mental retardation that are characterized by cognitive impairments and changes to other physical characteristics. A goal in the study of these diseases has been to understand the mechanisms that underlie the cognitive impairments present in these two disorders of mental retardation. A great deal of effort has been made to study synaptic function and structure in these disorders of mental retardation in order to determine whether there are any alterations present. Alterations to synaptic structure and function present during these disorders may give insight to the neural basis of the cognitive impairments that are characteristic of this disorder of mental retardation. An area of the brain that may be affected by these disorders is the hippocampus. This area of the brain has been extensively studied for its role in memory and alterations to synaptic function and structure may underlie some of the memory deficits present in these disorders of mental retardation. Both Down Syndrome patients and Fragile X Syndrome patients have deficits in their performance on memory tests. Down Syndrome patients also have a reduction in the number of neurons present in the hippocampus (Carlesimo et al., 1997). Fragile X Syndrome patients had structural abnormalities in the hippocampus including an enlargement of ventricular spaces (Jakala et al., 1997). Synaptic function and structure in the hippocampus of mouse models of Down Syndrome and Fragile X Syndrome were studied in order to determine this region of the brain was affected. Electrophysiology recordings in area CA3 of the hippocampus of the Ts65Dn Down Syndrome mouse model indicated there were disruptions to synaptic connectivity, decreases in excitatory and inhibitory synaptic transmission, and also a reduction in intrinsic interneuron activity. Imaging studies of CA3 in the Ts65Dn mouse did not show alterations to the number of synapses or structure of synapses suggesting that the alterations found with electrophysiology recordings are the result of functional changes to synapses. Electrophysiology study of the hippocampus in mouse models of Fragile X Syndrome has shown that inhibitory function was generally intact but that excitatory axons from neurons that lacked the Fragile X Mental Retardation Protein (FMRP) were less competitive at forming synapses in a mosaic expression system of the Fmr1 gene the lack of which causes the disease. These studies indicate that alterations to synaptic structure and function are present in the hippocampus of these mouse models of mental retardation. The differences however, were not the same in Down Syndrome and Fragile X Syndrome mouse models. Nonetheless, it is possible that the changes to synaptic function found in both of these mouse models leads to altered network function in the hippocampus which may, in turn, be the underlying cause of the memory deficits present in these disorders of mental retardation. The data presented in these studies indicate that the study of these mouse models of mental retardation can give insight to alterations caused by these disorders of mental retardation which may also lead to the development of new treatments.
  • 2008 Springer
    Brody, Baruch A.; Lustig, B. Andrew; McKenny, Gerald P.
  • 2010
    Johnson, Brandon Eugene; Aldrich, R. W.; Clandinin, Thomas R.; Goodman, Miriam Beth; Lewis, Richard; Shen, Kang.
    Ion channels coordinate the movement of ions across biological membranes in response to a diversity of cellular signals to regulate most if not all aspects of physiology. The large-conductance Ca2+- and voltage-activated potassium (BK) channel is widely expressed across tissues and functions to repolarize action potentials, regulate smooth muscle tone and endocrine function, and tune auditory hair cells. In all tissues, BK channels provide a functional link between cytosolic Ca2+ and membrane excitation. Extensive alternate splicing of the slo-1 gene, encoding the BK channel, significantly diversifies channel function. We identified all twelve predicted BK channel splice variants expressed by the nematode Caenorhabditis elegans, and measured the Ca2+ and voltage dependence for each. Alternate exons encode portions of two regions of the cytoplasmic tail: the RCK domain, important for Ca2+ coordination, and an unstructured region, termed the C-linker. Using the patch clamp technique, we determined that alternate splicing across multiple sites diversifies activation kinetics and Ca2+ sensitivity by manipulating the functional interaction between the RCK domain and C-linker. We recovered two slo-1 alleles (pg34 and pg52) that contain point-mutations near an alternative splice site in the C-linker from a mutant screen. Using real-time PCR, we determined that both mutations change slo-1 splice variant expression profiles. The pg34 mutation encodes an A698T substitution, and the pg52 mutation is located in an intron. When heterologously expressed, the A698T mutation changes BK channel Ca2+ sensitivity in specific splice variant backgrounds by disrupting the functional connection between the C-linker and the RCK domain. Using in vivo electrophysiology, we determined that the pg34 mutation reduces but does not abolish BK channel function in C. elegans neurons. These results suggest that alternate splicing of slo-1 modulates the functional connection between the RCK domain and the C-linker of the BK channel to establish a proper balance between intracellular Ca2+ and membrane excitation in a variety of cell type and physiological conditions.
  • 2008
    Brenner, Jacob Samuel.
    Status: Not Checked OutLane Catalog Record
  • 2010 Springer
    Alaoui-Jamali, Moulay A.
    Overview of efficacy and limitation of standard and targeted therapy for malignant disease using lung cancer as a case study -- Overview of current TCM practice and potential impacts on conventional therapies -- Complementary and alternative medicine for cancer care in India: basic and clinical perspective -- Esophageal cancer -- Gastric cancer -- Colorectal cancer -- Liver cancer -- Pancreatic cancer -- Breast cancer -- Ovarian cancer -- Prostate cancer -- Kidney cancer -- Bladder cancer -- Brain cancer -- Complementary and alternative treatments for the management of cancer-related fatigue -- Complementary and alternative treatments for the management of cancer-related pain -- Challenges conducting clinical trials with herbal products in oncology -- Herbal product-drug interactions from a pharmacological perspective -- Patient-physician relationship: creating an optimal healing environment -- Legal issues in alternative treatment of cancer -- Intellectual property for alternative medicine -- Chemical-biology of natural products from medicinal plants for cancer therapy -- Flavonoids in cancer prevention and therapy: chemistry, pharmacology, mechanisms of action, and perspectives for cancer drug discovery -- Marine natural products and their synthetic derivatives for cancer therapy -- Natural product-like scaffolds for molecular dissection of macromolecular interactions and new therapeutic applications -- Mining natural product-derived molecules against cancer targets: the case of the androgen receptor in prostate cancer.
  • *Robbins-Roth, Cynthia.
    Status: Not Checked OutLane Catalog Record
  • 2006 ScienceDirect
    Robbins-Roth, Cynthia.
    A scientist gone bad : how I went from the bench to the boardroom / Cynthia Robbins-Roth -- Technical writing : making sense out of manuals / Clayton R. Randall (second edition updated by Cynthia Robbins-Roth) -- Science writing : communicating with the masses / Sue Goetinck Ambrose -- Creating a publishing empire : how I gave up academic and became an entrepreneurial editor / Roger Longman -- Business information services : providing the data for industry / Mark D. Dibner -- Becoming a venture capitalist / Deepa Pakianathan -- Investment banking : dreams and reality / Peter Drake (second edition updated by Cynthia Robbins-Roth) -- How I became an analyst : science-based investment advising / Mary Ann Gray -- Entrepreneur and company founder : starting your own company and surviving / Ron Cohen -- Business development : making deals with science / Ronald Pepin -- The growth of a manager : from pure research to policy administration / Philip W. Hammer -- Regulatory affairs : keeping product development on track / Elizabeth D. Moyer -- Patent law careers : protecting the intellectual property of science / Alexandra J. Baran -- Entering biomedical and scientific consulting / Robert Roth -- Sales and marketing : so you want to sell? / Erin Hall Meade -- From doing research to moving research : my life in tech transfer / Paula Szoka -- Corporate communications : helping companies sell their stories / Tony Russo -- Executive search : the hunt for exceptional talent / Bente Hansen -- Consultant to the stars : advising CEOs for fun and profit / Carol Hall -- Biomedical consultant : specializing in technology assessment, strategic planning, and grant writing / Gail Schechter -- Science and public policy : translating between two worlds / David Applegate -- Economic development advisor : building a biotech industry for an entire country / Gina Lento -- Government agencies : directing science in the military / Genevieve Haddad -- Appendix : information resources about alternative careers for scientists / Cynthia Robbins-Roth.
  • 2003 ebrary
    Fast, Avital; Wainapel, Stanley F.
  • 2006 Springer
    Jeanteur, Ph.
    Methods and platforms for the quantification of splice variants' expression / Laurent Bracco ... [et al.] -- Pre-mRNA missplicing as a cause of human disease / Tatyana Novoyatleva ... [et al.] -- Alternative splicing : therapeutic target and tool / Mariano A. Garcia-Blanco -- SR proteins as potential targets for therapy / Johann Soret, Mathieu Gabut, Jamal Tazi -- Misregulation of tau alternative splicing in neurodegeneration and dementia / Athena Andreadis -- Spinal muscular atrophy and therapeutic prospects / Brunhilde Wirth, Lars Brichta, Eric Hahnen -- Misregulation of alternative splicing causes pathogenesis in myotonic dystrophy / N. Muge Kuyumcu-Martinez, Thomas A. Cooper -- Redirecting splicing to address dystrophin mutations : molecular by-pass surgery / Stephen D. Wilton, Susan Fletcher -- Altered splicing in prelamin A-associated premature aging phenotypes / Annachiara De Sandre-Giovannoli, Nicolas Levy -- Splicing modulation as a modifier of the CFTR function / Malka Nissim-Rafinia, Batsheva Kerem.
  • 2007
    Blencowe, Benjamin J.; Graveley, Brenton R.
  • Status: Not Checked OutLane Catalog Record
  • 2015 Springer
    Erverdi, Nejat; Motro, Melih.
    This book describes a new method of alveolar distraction osteogenesis that offers important advantages and can be used for the treatment of various orthopedic abnormalities and congenital malformations. Detailed guidance is provided on selection of patients suitable for alveolar distraction, including those with cleft lip and palate, skeletal class II malocclusions, and cystic lesions involving the alveolus. All aspects of treatment using the ArchWise distraction appliance are then covered, including technical preparation, surgical set-up and osteotomies, docking site surgery, orthodontic finishing, implant placement, and prosthetic restorations. Relevant information is also included on the principles of distraction osteogenesis and bone histology and quality after the procedure. The book concludes with helpful case presentations covering different scenarios in which ArchWise distraction of alveolar bone is appropriate.
  • 2016
    Ludwig, David.
    Status: Not Checked OutLane Catalog Record
    "Inspired by the New York Times op-ed "Always Hungry," ALWAYS HUNGRY? will change everything readers ever thought about weight loss, diet, and health. Groundbreaking new research shows that calorie counting does not work for weight loss: one diet causes weight gain whereas another diet with the same calorie count doesn't. It's your fat cells that are to blame for causing excessive hunger and increased weight. By eating the wrong foods, our fat cells are triggered to take in too many calories for themselves, setting off a dangerous chain reaction of increased appetite and a slower metabolism. Now, Harvard Medical School's David Ludwig, MD, PhD, offers an impeccably researched diet that will turn dieting on its head, teaching readers to reprogram their fat cells, tame hunger, boost metabolism, and lose weight--for good"-- Provided by publisher.
  • 2006 Springer
    Jucker, M.
  • 2013
    Lock, Margaret M.
    Status: Not Checked OutLane Catalog Record
    Based on a careful study of the history of Alzheimer's disease and extensive in-depth interviews with clinicians, scientists, epidemiologists, geneticists, and others, Margaret Lock highlights the limitations and the dissent implicated in this approach. She stresses that one major difficulty is the well-documented absence of behavioral signs of Alzheimer's disease in a significant proportion of elderly individuals, even when Alzheimer neuropathology is present in their brains. This incongruity makes it difficult to distinguish between what counts as normal versus pathological and, further, makes it evident that social and biological processes contribute inseparably to aging. Lock argues that basic research must continue, but it should be complemented by a realistic public health approach available everywhere that will be more effective and more humane than one focused almost exclusively on an increasingly frenzied search for a cure.
  • 2007 Springer
    Sisodia, Sangram S.; Tanzi, Rudolph E.
  • 2012 Karger
    Carrillo, M. C.; Hampel, H.
    The global impact of Alzheimer's disease / M.C. Carrillo, W. Thies, L.J. Bain -- The genetics of Alzheimer's disease / M.C. Schu ... [et al.] -- Current conceptual view of Alzheimer's disease / K. Herrup -- Neuropathological basis of Alzheimer's disease and Alzheimer's disease diagnosis / J.A. Schneider ... [et al.] -- Diagnostic tools : fluid biomarkers for Alzheimer's disease / H. Zetterberg, H. Hampel, K. Blennow -- MRI-and PET-based imaging markers for the diagnosis of Alzheimer's disease / S. Teipel ... [et al.] -- Changing diagnostic concepts of Alzheimer's disease / G.M. McKhann, M.S. Albert, R.A. Sperling -- Pharmacological treatment of Alzheimer's disease / L.S. Schneider -- Regulatory requirements on clinical trials in Alzheimer's disease / K. Broich ... [et al.] -- Perspectives on Alzheimer's disease : past, present and future / Z.S. Khachaturian.
  • 2010 Springer Protocols
    Roberson, Erik D.
    Contemporary Approaches to Alzheimer's Disease and Frontotemporal Dementia / Erik D. Roberson -- Preparing Synthetic Aβ in Different Aggregation States / W. Blaine Stine, Lisa Jungbauer, Chunjiang Yu, Mary Jo LaDu -- Isolation of Low-n Amyloid β-Protein Oligomers from Cultured Cells, CSF, and Brain / Ganesh M. Shankar, Alfred T. Welzel, Jessica M. McDonald, Dennis J. Selkoe, Dominic M. Walsh -- Detecting Aβ*56 Oligomers in Brain Tissues / Mathew A. Sherman, Sylvain E. Lesné -- Assessing Aβ Aggregation State by Atomic Force Microscopy / Justin Legleiter -- Measuring APP Carboxy-Terminal Fragments / Luke A. Esposito -- Detection of APP Intracellular Domain in Brain Tissue / Sanjay W. Pimplikar, Anupama Suryanarayana -- Cell-Based Assays for Regulators of Tau Biology / Umesh K. Jinwal, Chad A. Dickey -- Split GFP Complementation Assay for Quantitative Measurement of Tau Aggregation In Situ / Wanjoo Chun, Geoffrey S. Waldo, Gail V. Johnson -- Apolipoprotein E Expression and Purification / Yvonne Newhouse, Karl H. Weisgraber -- Aβ Toxicity in Primary Cultured Neurons / Adriana Ferreira, Roxana C. Sinjoanu, Alexandra Nicholson, Sara Kleinschmidt -- Manipulation of Gene Expression in the Central Nervous System with Lentiviral Vectors / Binggui Sun, Li Gan -- Selecting a Mouse Model of Alzheimer's Disease / Jeannie Chin -- Monitoring Spatial Learning and Memory in Alzheimer's Disease Mouse Models Using the Morris Water Maze / Kimberly Scearce-Levie -- Step-by-Step In Situ Hybridization Method for Localizing Gene Expression Changes in the Brain / Jorge J. Palop, Erik D. Roberson, Inma Cobos -- Real-Time Visualization of Axonal Transport in Neurons / Yasuko Osakada, Bianxiao Cui -- Quantifying Biomarkers of Cognitive Dysfunction and Neuronal Network Hyperexcitability in Mouse Models of Alzheimer's Disease: Depletion of Calcium-Dependent Proteins and Inhibitory Hippocampal Remodeling / Jorge J. Palop, Lennart Mucke, Erik D. Roberson -- Epigenetic Changes in the Brain: Measuring Global Histone Modifications / Gavin Rumbaugh, Courtney A. Miller.
  • 2007
    Iverson, Cheryl.
    Status: Not Checked OutLane Catalog Record
    Types of articles -- Manuscript preparation -- References -- Visual presentation of data -- Ethical and legal considerations -- Editorial assessment and processing -- Grammar -- Punctuation -- Plurals -- Capitalization -- Correct and preferred usage -- Non-English words, phrases, and accent marks -- Medical indexes -- Abbreviations -- Nomenclature -- Eponyms -- Greek letters -- Units of measure -- Numbers and percentages -- Study design and statistics -- Mathematical composition -- Typography -- Manuscript editing and proofreading -- Glossary of publishing terms -- Resources.
    Also available: Print – 2007
  • 2006 Springer
    Flindt, Rainer.
  • 2015 Springer
    Mackway-Jones, Kevin; Wankhade, Paresh.
    Introduction: Understanding the Management of Ambulance Services / Paresh Wankhade and Kevin Mackway-Jones -- Historical Perspectives in the Ambulance Service / Alexander Pollock -- A Strategy for Managing Quality in Ambulance Services / Mary Peters, Steve Barnard, Michael Dorrian and Kevin Mackway-Jones -- Management of Emergency Demand / Bob Williams -- Ethical Commissioning of Emergency Ambulance Services / Mark Docherty -- Organisational and Professional Cultures: An Ambulance Perspective / Paresh Wankhade, James Radcliffe and Geoffrey Heath -- Leadership and System Thinking in the Modern Ambulance Service / Andy Newton and Graham Harris -- Ambulance Service Modernisation / Robert Till and Anthony Marsh -- Interoperability and Multiagency Cooperation / John Stephenson -- Responding to Diversity and Delivering Equality in Prehospital Care: Statutory Responsibilities, Best Practice and Recommendations / Viet-Hai Phung, Karen Windle and A. Niroshan Siriwardena -- Dealing with the Austerity Challenge / Robert Till and Anthony Marsh -- The Ambulance Service of the Future / Mark Docherty, Andrew Carson and Matthew Ward -- Future Perspectives for the UK Ambulance Services: Evolution Rather than Revolution / Kevin Mackway-Jones and Paresh Wankhade -- International Perspectives: Australian Ambulance Services in 2020 / Paul M Middleton -- International Perspectives: South African Ambulance Services in 2020 / Craig Vincent-Lambert -- International Perspectives: Finnish Ambulance Services in 2020 / Juha Jormakka and Simo Saikko -- Index.
  • 2010 Springer
    Neal-Perry, Genevieve; Santoro, Nanette.
    Amenorrhea: A Case-Based Clinical Guide is a comprehensive review of the current knowledge regarding normal female reproductive physiology. Replete with interesting case vignettes and providing diagnostic algorithms and therapeutic strategies for amenorrhea, Amenorrhea: A Case-Based Clinical Guide is divided into three sections. The first section is composed of two chapters that provide a thorough review of basic science and clinical knowledge about the organ systems responsible for normal physiology of the menstrual cycle. The second section includes discussion about menstrual cycle disruption as it relates to hypothalamic-pituitary dysfunction, surgical and natural menopause, genetic defects, premature ovarian failure/insufficiency and the effects of caloric excess and restriction. The third section offers an update on the physiological effects of prolonged amenorrhea induced surgically or by hypothalamic dysfunction and also includes an original chapter that focuses solely on the impact of race and ethnicity on the prevalence and diagnosis of amenorrhea. Amenorrhea: A Case-Based Clinical Guide brings together chapters from renowned experts who offer state-of-the-art, clinically useful information in a case-based, reader-friendly fashion. This title will be a welcome addition to the bookshelves of all clinicians who practice in women's health settings.
  • 1939-
    Hooton, Earnest Albert.
    Status: Not Checked OutLane Catalog Record
  • 1854-
    King, John; Felter, Harvey Wickes; King, John.
    Status: Not Checked OutLane Catalog Record
  • v. 1, 2000.
    Byrd, W. Michael; Clayton, Linda A.
    Status: Not Checked OutLane Catalog Record
    V. 1. A Medical history of African Americans and the problem of race : beginnings to 1900
  • 2010.
    Status: Not Checked OutLane Catalog Record
    Also available: Print – 1989/90-2009
  • v. 1-3. Google Books
    Fulltext (v. 3) Google Books
    Beach, W.
    Also available: Print – v. 1-3., 1833-
  • 2006 PsychiatryOnline
    Psychiatric evaluation of adults, second edition -- Treatment of patients with delirium -- Treatment of patients with Alzheimer's disease and other dementias of late life -- Treatment of patients with HIV/AIDS -- Treatment of patients with substance use disorders, second edition -- Treatment of patients with schizophrenia, second edition -- Treatment of patients with major depressive disorder, second edition -- Treatment of patients with bipolar disorder, second edition -- Treatment of patients with panic disorder -- Treatment of patients with acute stress disorder and posttraumatic stress disorder -- Treatment of patients with eating disorders, third edition -- Treatment of patients with borderline personality disorder -- Assessment and treatment of patients with suicidal behaviors. -- Appendix: Practice guideline development process.
  • 2015 PsychiatryOnline
    Blazer, Dan G.; Steffens, David C.; Thakur, Mugdha E.
    Demography and epidemiology of psychiatric disorders in late life / Celia F. Hybels, Ph.D., and Dan G. Blazer, M.D., Ph.D -- Physiological and clinical considerations of geriatric patient care / Robert M. Kaiser, M.D., M.H.Sc -- Genomics in geriatric psychiatry / Aaron M. Koenig, M.D., and Robert A. Sweet, M.D -- The psychiatric interview of older adults / Dan G. Blazer, M.D., Ph.D -- Use of the laboratory in the diagnostic workup of older adults / Sophia Wang, M.D., Mugdha Thakur, M.D., and P. Murali Doraiswamy, M.B.B.S., F.R.C.P -- Neuropsychological assessment of dementia / Kathleen A. Welsh-Bohmer, Ph.D., AND Deborah K. Attix, Ph.D -- Delirium / Jane S. Saczynski, Ph.D., AND Sharon K. Inouye, M.D., M.P.H -- Dementia and mild neurocognitive disorders / Eitan Z. Kimchi, M.D., and Constantine G. Lyketsos, M.D., M.H.S -- Mood disorders / David C. Steffens, M.D., M.H.Sc -- Bipolar disorder in late life / John L. Beyer, M.D -- Schizophrenia spectrum and other psychotic disorders / Jeanne E. Maglione, M.D., Ph.D., Ipsit V. Vahia, M.D., and Dilip V. Jeste M.D -- Anxiety disorders / Eric J. Lenze, M.D., Jan Mohlman, Ph.D., and Julie Loebach Wetherell, Ph.D -- Somatic symptom and related disorders / Marc E. Agronin, MD -- Sexuality and aging / Marc E. Agronin, MD -- Bereavement / Moria J. Smoski, Ph.D., Stephanie T. Jenal, Ph.D., and Larry W. Thompson, Ph.D -- Sleep and circadian rhythm disorders / Andrew D. Krystal, M.D., M.S., and Mugdha Thakur, M.D -- Alcohol and drug problems / Shahrzad Mavandadi, Ph.D., and David W. Oslin, M.D -- Personality disorders / Thomas E. Oxman, M.D -- Agitation and suspiciousness / Mugdha E. Thakur, M.D., and Lisa P. Gwyther, M.S.W -- Psychopharmacology / Benoit H. Mulsant, M.D., and Bruce G. Pollock, M.D., Ph.D -- Electroconvulsive therapy and other forms of brain stimulation / Richard D. Weiner, M.D., Ph.D., and Mustafa M. Husain, M.D -- Nutrition and physical activity / Kathryn Porter Starr, Ph.D., R.D., Connie Watkins Bales, Ph.D., R.D., and Martha E. Payne, Ph.D., R.D., M.P.H -- Individual and group psychotherapy / Moria J. Smoski, Ph.D., and Patricia A. Arean, Ph.D -- Working with families of older adults / Lisa P. Gwyther, M.S.W., and Diane E. Meglin, M.S.W -- Clinical psychiatry in the nursing home / Joel E. Streim, M.D.
  • 2014 PsychiatryOnline
    Hales, Robert E.; Roberts, Laura Weiss; Yudofsky, Stuart C.
  • 2009 PsychiatryOnline
    Nemeroff, Charles B.; Schatzberg, Alan F.
  • 2015 PsychiatryOnline
    Brady, Kathleen; Galanter, Marc; Kleber, Herbert D.
    Section I. The basis of addictive disorders -- Neurobiology of addiction -- Genetics of addiction -- Epidemiology of addiction -- Cross-cultural aspects of addiction -- Section II. The nature of treatment -- Science in the treatment of substance abuse -- Assessment of the patient -- Screening and brief intervention -- Patient placement criteria -- "Recovery" in chronic care disease management -- Section III. Specific drugs of abuse -- Neurobiology of alcohol use disorder -- Treatment of alcohol intoxication and alcohol withdrawal -- Neurobiology of stimulants -- Clinical management: cocaine -- Clinical management: methamphetamine -- Hallucinogens and club drugs -- Tobacco use disorder -- Benzodiazepines and other sedatives and hypnotics -- Treatment of anabolic-androgenic steroid-related disorders -- Neurobiology of opiates and opioids -- Opioid detoxification -- Methadone and buprenorphine maintenance -- Opioid antagonists -- Neurobiology of marijuana -- Treatment of cannabis use disorder -- Section IV. Treatment modalities -- Psychodynamic psychotherapy -- Cognitive-behavioral therapies -- Motivational enhancement -- Twelve-step facilitation -- Contingency management -- Network therapy -- Group therapy -- Family therapy -- Section V. Rehabilitation settings -- Inpatient treatment -- Therapeutic communities -- Community-based treatment -- History of alcoholics anonymous and the experiences of patients -- Psychological mechanisms in alcoholics anonymous -- Outcomes research on twelve-step programs -- Section VI. Special populations -- Women and addiction -- Perinatal substance use disorders -- Adolescent substance use disorders: epidemiology, neurobiology, and screening -- Adolescent substance use disorders: transition to substance abuse, prevention, and treatment -- Psychiatric consultation in pain and addiction -- Prevention of prescription drug abuse -- HIV/AIDS and hepatitis C -- Substance use disorders among physicians -- Substance use issues among gay, lesbian, bisexual, and transgender people -- Minorities -- Section VII. Special topics -- Testing to identify recent drug use -- Medical education on addiction -- Prevention of substance abuse -- Forensic addiction psychiatry -- Substance abuse and mental illness -- Substance-related and addictive disorders.
  • 2008
    Galanter, Marc; Kleber, Herbert D.
    Status: Not Checked OutLane Catalog Record
    Part 1 : The basis of addictive disorders -- Neurobiology of addiction / George F. Koob -- Genetics of addiction / Joel Gelernter, Henry R. Kranzler -- Epidemiology of addiction / Judith S. Brook, Kerstin Pahl, Elizabeth Rubenstone -- Cross-cultural aspects of addiction / Nady el-Guebaly -- Part 2 : The nature of treatment -- Assessment of the patient / Shelly F. Greenfield, Grace Hennessy -- Patient placement criteria / David Mee-Lee, David R. Gastfriend -- Evolution in addiction treatment concepts and methods / A. Thomas McLellan -- Part 3 : Specific drugs of abuse -- Alcohol -- Neurobiology of alcohol / Clifford M. Knapp, Domenic A. Ciraulo, Henry R. Kranzler -- Clinical management of alcohol abuse and dependence / Hugh Myrick, Tara Wright -- Stimulants -- Neurobiology of stimulants / Margaret Haney -- Clinical management : cocaine / Thomas R. Kosten, Mehmet Sofuoglu, Tracie J. Gardner -- Clinical management : methamphetamine / Richard A. Rawson, Walter Ling -- Hallucinogens and club drugs -- Neurobiology of hallucinogens / Richard A. Glennon -- Hallucinogens and club drugs / Michael F. Weaver, Sidney H. Schnoll -- Other substances -- Nicotine and tobacco / Tony P. George, Andrea H. Weinberger -- Benzodiazepines and other sedatives and hypnotics / Adam Bisaga -- Treatment of anabolic-androgenic steroid-related disorders / Harrison G. Pope, Jr., Kirk J. Brower -- Opioids -- Neurobiology of opiates and opioids / Mary Jeanne Kreek -- Detoxification of opioids / Soteri Polydorou, Herbert D. Kleber -- Opioid maintenance treatment / Richard S. Schottenfeld -- Buprenorphine maintenance / Eric C. Strain, Michelle R. Lofwall -- Antagonists of opioids / Charles O'Brien, Kyle M. Kampman -- Part 4 : Treatment modalities -- Psychodynamics / Hallie A. Lightdale, Avram H. Mack, Richard J. Frances -- Cognitive-behavioral therapies / Kathleen M. Carroll -- Motivational enhancement / Carlo C. DiClemente, Miranda Garay, Leigh Gemmell -- Twelve-step facilitation / Richard K. Ries, Marc Galanter, J. Scott Tonigan -- Contingency management / Stephen T. Higgins, Kenneth Silverman -- Network therapy / Marc Galanter -- Group therapy / David W. Brook -- Family therapy / Timothy J. O'Farrell, William Fals-Stewart -- Part 5 : Rehabilitation settings -- Inpatient treatment / Roger D. Weiss, Jennifer Sharpe Potter, Rocco A. Iannucci -- Therapeutic communities / George De Leon -- Community-based treatment / Jonathan I. Ritvo, Harvey L. Causey III -- Alcoholics anonymous and other 12-step programs -- Psychological mechanisms in alcoholics anonymous / J. Scott Tonigan, Gerard J. Connors -- The history of alcoholics anonymous and the experiences of patients / Edgar P. Nace -- Outcome research on 12-step and other self-help programs / Rudolf H. Moos, Christine Timko -- Part 6 : Special populations -- Adolescent substance abuse / Yifrah Kaminer -- The mentally ill substance abuser / Stephen Ross -- Women and addiction / Kathleen T. Brady, Sudie E. Back -- Perinatal substance abuse / Loretta P. Finnegan, Stephen R. Kandall -- HIV/AIDS and hepatitis C / Steven L. Batki, Kalpana I. Nathan -- Prescription drug abuse / Wilson M. Compton, Richard Denisco -- Substance use disorders among physicians / J. Wesley Boyd, John R. Knight -- Gay men and lesbians / Robert Paul Cabaj -- Minorities / Joseph Westermeyer, Daniel Dickerson -- Part 7 : Special topics -- Testing to identify recent drug use / Robert L. DuPont, Carl M. Selavka -- Medical education / Erik W. Gunderson, Frances R. Levin, Petros Levounis -- Prevention of substance abuse / Richard R. Clayton, Melissa J.H. Segress, Crystal A. Caudill -- Forensic addiction psychiatry / Avram H. Mack, Monica Barros.
  • Google Books
    Metcalf, Leonard; Eddy, Harrison Prescott.
    I. Design of sewers -- II. Construction of sewers -- III. Disposal of sewage.
    Also available: Print – 1916-
  • 2012 Springer Protocols
    Alterman, Michail A.; Hunziker, Peter.
    Rapid LC-MS/MS profiling of protein amino acids and metabolically related compounds for large-scale assessment of metabolic phenotypes -- Combination of an AccQ. Tag-ultra performance liquid chromatographic method with tandem mass spectrometry for the analysis of amino acids -- Isotope dilution liquid chromatography-tandem mass spectrometry for quantitative amino acid analysis -- Analysis of underivatized amino acids: Zwitterionic hydrophilic interaction chromatography combined with triple quadrupole tandem mass spectrometry -- Amino acid analysis via LC-MS method after derivatization with quaternary phosphonium -- Amino acid analysis by hydrophilic interaction chromatography coupled with isotope dilution mass spectrometry -- A universal HPLC-MS method to determine the stereochemistry of common and unusual amino acids -- Amino acid analysis by capillary electrophoresis-mass spectrometry -- New advances in amino acid profiling by capillary electrophoresis-electrospray ionization-mass spectrometry -- Optimal conditions for the direct RP-HPLC determination of underivatized amino acids with online multiple detection -- Absolute quantitation of proteins by acid hydrolysis combined with amino acid detection by mass spectrometry -- Amino acid analysis by means of MALDI TOF mass spectrometry or MALDI TOF/TOF tandem mass spectrometry -- Heptafluorobutyl chloroformate-based sample preparation protocol for chiral and nonchiral amino acid analysis by gas chromatography -- The EZ:Faast family of amino acid analysis kits: Application of the GC-FID kit for rapid determination of plasma tryptophan and other amino acids -- Amino acid analysis in physiological samples by GC-MS with propyl chloroformate derivatization and iTRAQ-LC-MS/MS -- Automated analysis of primary amino acids in plasma by high-performance liquid chromatography -- RP-LC of phenylthiocarbamyl amino acid adducts in plasma acetonitrile extracts: Use of multiple internal standards and variable wavelength UV detection -- Quantification of underivatised amino acids on dry blood spot, plasma, and urine by HPLC-ESI-MS/MS -- Capillary electrophoresis of free amino acids in physiological fluids without derivatization employing direct or indirect absorbance detection -- Measurement of 3-nitro-tyrosine in human plasma and urine by gas chromatography-tandem mass spectrometry -- Analysis of hydroxyproline in collagen hydrolysates -- Innovative and rapid procedure for 4-hydroxyproline determination in meat-based foods -- Multiple reaction monitoring for the accurate quantification of amino acids: Using hydroxyproline to estimate collagen content -- Sequential injection chromatography for fluorimetric determination of intracellular amino acids in marine microalgae -- Direct analysis of underivatized amino acids in plant extracts by LC-MS-MS -- Wheat gluten amino acid analysis by high-performance anion-exchange chromatography with integrated pulsed amperometric detection -- Preparative HPLC separation of underivatized amino acids for isotopic analysis -- Quantification of amino acids in a single cell by microchip electrophoresis with chemiluminescence detection.
  • 2007 Springer
    Wendisch, Volker F.
  • 2012 CRCnetBASE
    Ashmead, H. DeWayne.
    Ch. 1. The fundamentals of mineral nutrition -- ch. 2. The chemistry of chelation -- ch. 3. The history of nutritional chelates -- ch. 4. The requirements for a nutritionally functional chelate -- ch. 5. The development of analytical methods to prove amino acid chelation -- ch. 6. Absorption of amino acid chelates from the alimentary canal -- ch. 7. The pathways for absorption of an amino acid chelate -- ch. 8. The absorption of amino acid chelates by active transport -- ch. 9. The absorption of amino acid chelates by facilitated diffusion -- ch. 10. The fate of amino acid chelates in the mucosal cell -- ch. 11. The uptake of amino acid chelates into and out of the plasma -- ch. 12. Tissue metabolism of amino acid chelates -- ch. 13. Some metabolic responses of the body to amino acid chelates -- ch. 14. Toxicity of amino acid chelates -- ch. 15. The absorption and metabolism of amino acid chelates.
  • 2013 CRCnetBASE
    Wu, Guoyao.
    This up-to-date book presents basic concepts and recent advances in amino acid biochemistry and nutrition, providing comprehensive coverage of developments over the past 45 years. It includes information on absorption, metabolism, and excretion of amino acids while addressing protein quality and requirements. The text discusses metabolic pathways of amino acids in relation to health and disease in various organisms, as well as species differences in metabolism of amino acids. The author also presents a critical analysis of amino acid supplementation to humans and animals.
  • 2008 CRCnetBASE
    Di Pasquale, Mauro G.
  • v. 1A, 2A-B, 1969, 1965-66.
    Jeanloz, Roger W.; Balazs, Endre A. .
    Status: Not Checked OutLane Catalog Record
    v. 1A. Jeanloz, Roger W., ed. Chemistry of amino acids -- v. 2A. Distribution and biological role -- v. 2B. Metabolism and interactions.
  • 2012 ScienceDirect
    2012 ClinicalKey
    Aminoff, Michael J.
    The emergence of electrophysiology as an aid to neurology / Mary A.B. Brazier -- Electrophysiologic equipment and electrcial safety / John A. Cadwell and Richard A. Villarreal -- Electroencephalography and magnetoencephalography. Electroencephalography: general principles and clinical applications / Michael J. Aminoff -- Neonatal and pediatric electroencephalography / Jin S. Hahn -- Electroencephalographic artifacts and benign variants / Jeffrey W. Britton -- Video-EEG monitoring for epilepsy / John M. Stern and Jerome Engel, Jr. -- Invasive clinical neurophysiology in epilepsy and movement disorders / William J. Marks, Jr and Kenneth D. Laxer -- Topographic mapping, frequency analysis, and other quantitative techniques in electroencephalography / Marc R. Nuwer and Pedro Coutin-Churchman -- Intraoperative electroencephalographic monitoring during carotid endarterectomy and cardiac surgery / Gregory D. Cascino and Frank W. Sharbrough, III -- Magnetoencephalography / William W. Sutherling -- Electromyography, nerve conduction studies, and related techniques. Clinical electromyography / Michael J. Aminoff -- Quantitative electromyography / Mark B. Bromberg -- Nerve conduction studies / Jasper R. Daube and Devon I. Rubin -- Microneurography and its potential clinical applications / David Burke -- Nerve excitability: a clinical translation / Matthew C. Kiernan and Cindy Shin Yi Lin -- Neuromuscular ultrasound as a complement to the electrodiagnostic evaluation / Francis O. Walker and Michael S. Cartwright -- Electrophysiologic study of disorders of neuuromuscular transmission / Donald B. Sanders -- H-reflex and F-response studies / Morris A. Fisher -- The blink reflex and other cranial nerve reflexes / Josep Valls-Sole -- Electrophysiologic evaluation of movement disorders / Mark Hallett -- Evaluation of the autonomic nervous system / Michael J. Aminoff -- Evoked potentials and related techniques. Visual evoked potentials, electroretinography, and other diagnostic approaches to the visual system / Ari J. Green -- Visual evoked potentials in infants and children / Eileen E. Birch and Vidhya Subramanian -- Brainstem auditory evoked potentials: methodology, interpretation, and clinical application / Alan D. Legatt -- Brainstem auditory evoked potentials in infants and children / Terence W. Picton, margot J. Taylor, and Andree Durieux-Smith -- Somatosensory evoked potentials / Michael J. Aminoff and Andrew Eisen -- Somatosensory evoked potentials in infants and children / Michael J. Aminoff -- Diagnostic and therapeutic role of magnetic stimulation in neurologuy / Robert Chen and Nicolae Petrescu -- Event-related potentials / Douglas S. Goodin -- Intraoperative monitoring by evoked potential techniques / Ronald G. Emerson and David C. Adams -- Bladder, bowel, and sexual dysfunction. electrophysiologic evaluation of sacral function / Simon Podnar and David B. Vodusek -- Tests of vestibular function. Vestibular laboratory testing / Joseph M. Furman and Floris L. Wuyts -- Electrophysiologic evaluation in special situations. Polysomnographic evaluation fo sleep disroders / Vivien C. Abad and Christian Guilleminault -- Electrophysiologic evaluation of patients in the intensive care unit / G. Bryan Young and Charles F. Bolton -- Electrophysiologic evaluation of brain death: a critical appraisal / Thomas P. Bleck -- Electrophysiologic techniques in the evaluation of patients with suspected neurotoxic disorders / Michael J. Aminoff and James W. Albers.
  • 2014 ClinicalKey
    Aminoff, Michael J.; Josephson, Scott Andrew.
    Aminoff's Neurology and General Medicine is the standard and classic reference providing comprehensive coverage of the relationship between neurological practice and general medicine. As neurologists are asked to consult on general medical conditions, this reference provides an authoritative tool linking general medical conditions to specific neurological issues and disorders. This is also a valuable tool for the general practitioner seeking to understand the neurological aspects of their medical practice. Completely revised with new chapters covering metastatic disease, bladder disease, psychogenic disorders, dementia, and pre-operative and post-operative care of patients with neurologic disorders, this new edition will again be the go-to reference for both neurologists and general practitioners.
  • 2010 Springer
    Murray, Craig D.
  • 1973.
    Status: Not Checked OutLane Catalog Record
  • 2016 Springer
    Di Marino, Vincent.
    Preface -- Foreword -- History of the amygdala -- Formation of the amygdala -- Amygdala and Limbic system -- Functions of the amygdala -- Dissection of the amygdala -- Morphology of the amygdala -- Connections of the amygdala -- Projections from and toward amygdala -- The relationships of the amygdala -- The BST (bed nucleus of the stria terminalis) -- The extended amygdala -- Vascularization of the amygdala -- Consequences of the ablation -- Conclusions and prospects -- Bibliography -- Index.
  • 2015 Springer
    Dogan, Ahmet; Herrera, Guillermo A.; Picken, Maria M.
  • 2012 Springer
    Dogan, Ahmet; Herrera, Guillermo A.; Picken, Maria M.
    Abnormal proteins are known to be associated with various pathologies. Most notably, these include amyloidoses, monoclonal protein deposits associated with plasma cell dyscrasia/multiple myeloma, cryoglobulins and various related organized and non-organized deposits. Amyloid and Related Disorders presents an overview of the most recent developments in this area including clinical presentation, etiology, pathogenesis, and differential diagnosis. The rationale for various therapies, including transplantation, is discussed and tissue diagnosis (its pitfalls and strategies for avoiding them) and laboratory support are included. The involvement of all major organ systems including renal/genitourinary, cardiac, gastrointestinal, pulmonary, peripheral nerve/central nervous system, soft tissue and bone marrow pathology is covered. This approach provides a unifying concept of these pathologic processes, which have systemic involvement, and which have, hitherto, not been universally appreciated. Awareness of these diseases among a wider audience of pathologists may increase the rate of their diagnosis as well as that of earlier diagnosis. This volume will be invaluable to specialized and general pathologists as well as cytopathologists; other medical professionals may also benefit from this concise update on the systemic amyloidoses.
  • pt. [A]-C, 1999-2006. ScienceDirect
    pt. B, 2006 ScienceDirect
    pt. C, 2006 ScienceDirect
    Kheterpal, Indu; Wetzel, Ronald.
  • 2012 Springer Protocols
    Calero, Miguel; Gasset, Maria; Sigurdsson, Einar M.
    Rapid generation of dityrosine cross-linked A-[beta] oligomers via cu-redox cycling / Adam P. Gunn, Blaine R. Roberts, and Ashley I. Bush -- Application of photochemical cross-linking to the study of oligomerization of amyloidogenic proteins / Dahabada H.J. Lopes [and others] -- Preparation of stable amyloid b-protein oligomers of defined assembly order / Clark Rosensweig [and others] -- Purification and fibrillation of full-length recombinant PrP / Natallia Makarava and Ilia V. Baskakov -- Featuring amyloids with fourier transform infrared and circular dichroism spectroscopies / Miguel Calero and María Gasset -- Quasielastic light scattering study of amyloid b-protein fibrillogenesis / Aleksey Lomakin and David B. Teplow -- Conformations of microtubule-associated protein tau mapped by fluorescence resonance energy transfer / Sadasivam Jeganathan [and others] -- Measuring the kinetics of amyloid fibril elongation using quartz crystal microbalances / Alexander K. Buell, Christopher M. Dobson, and Mark E. Welland -- X-ray fibre diffraction studies of amyloid fibrils / Kyle L. Morris and Louise C. Serpell -- Structural characterization of prefibrillar intermediates and amyloid fibrils by small-angle x-ray scattering / Annette Eva Langkilde and Bente Vestergaard -- Atomic force fluorescence microscopy in the characterization of amyloid fibril assembly and oligomeric intermediates / Valeriy Ostapchenko, Maria Gasset, and Ilia V. Baskakov -- Investigating fibrillar aggregates of tau protein by atomic force microscopy / Susanne Wegmann, Daniel J. Muller, and Eckhard Mandelkow -- Structural studies of amyloids by quenched hydrogen-deuterium exchange by NMR / Marçal Vilar, Lei Wang, and Roland Riek -- Cyclic amplification of prion protein misfolding / Marcelo A. Barria, Dennisse Gonzalez-Romero, and Claudio Soto -- Search for amyloid-binding proteins by affinity chromatography / Miguel Calero, Agueda Rostagno, and Jorge Ghiso -- Establishing the links between A[beta] aggregation and cytotoxicity in vitro using biophysical approaches / Asad Jan and Hilal A. Lashuel -- Preparation of cultured human vascular cells / Ingvar H. Olafsson, Dadi Th. Vilhjalmsson, and Finnbogi R. Thormodsson -- Murine cerebrovascular cells as a cell culture model for cerebral amyloid angiopathy : isolation of smooth muscle and endothelial cells from mouse brain / Sebastien A. Gauthier [and others] -- In vitro assays measuring protection by proteins such as cystatin C of primary cortical neuronal and smooth muscle cells / Sebastien A. Gauthier [and others] -- Study of neurotoxic intracellular calcium signalling triggered by amyloids / Carlos Villalobos [and others] -- Bacterial amyloids / Yizhou Zhou [and others] -- Study of amyloids using yeast / Reed B. Wickner [and others] -- Cell-to-cell transmission of [alpha]-synuclein aggregates / Seung-Jae Lee [and others] -- Subcutaneous adipose tissue biopsy for amyloid protein studies / Per Westermark -- Analysis of s100 oligomers and amyloids / Hugo M. Botelho, Günter Fritz, and Cláudio M. Gomes -- S100A8/A9 amyloidosis in the ageing prostate : relating ex vivo and in vitro studies / Anna L. Gharibyan, Dina Raveh, and Ludmilla A. Morozova-Roche -- Isolation of amyloid by solubilization in water / Dadi Th. Vilhjalmsson, Indiana E. Ingolfsdottir, and Finnbogi R. Thormodsson -- Histological staining of amyloid and pre-amyloid peptides and proteins in mouse tissue / Hameetha B. Rajamohamedsait and Einar M. Sigurdsson -- Pentameric luminescent-conjugated oligothiophene for optical imaging of in vitro-formed amyloid fibrils and protein aggregates in tissue sections / K. Peter R. Nilsson, Mikael Lindgren, and Per Hammarström -- In vivo magnetic resonance imaging of amyloid-[beta] plaques in mice / Youssef Zaim Wadghiri [and others] -- Mouse model for scrapie : inoculation, clinical scoring, and histopathological techniques / Michele A. Di Bari, Romolo Nonno, and Umberto Agrimi -- Biochemical isolation of insoluble tau in transgenic mouse models of tauopathies / Carl Julien, Alexis Bretteville, and Emmanuel Planel -- Tissue processing prior to analysis of alzheimer's disease associated proteins and metabolites, including A[beta] / Stephen D. Schmidt, Ralph A. Nixon, and Paul M. Mathews -- A-[beta] measurement by enzyme-linked immunosorbent assay / Stephen D. Schmidt [and others] -- Cognitive and sensorimotor tasks for assessing functional impairments in mouse models of Alzheimer's Disease and related disorders / Allal Boutajangout [and others].
  • 2010
    Orr, Adrienne Lee; MacIver, M. Bruce; Madison, Daniel V.; Smith, Stephen J.; Wyss-Coray, Tony.
    Alzheimer's disease (AD) is a progressive neurodegenerative disorder affecting the elderly that is characterized by loss of short-term memory and cognitive decline. Studies in both human patients and animal models of AD point to over-accumulation of soluble oligomers of amyloid-beta peptide (Abeta) as a mediator of learning and memory impairments early in the disease (Rowan, Klyubin et al. 2005; Selkoe 2008). Support for Abeta's role in learning deficits comes from studies demonstrating impaired plasticity of synaptic inputs to neurons, as measured in the paradigm of long-term potentiation (LTP) of synaptic strength in hippocampal slices (Chen, Kagan et al. 2000; Freir, Holscher et al. 2001; Walsh, Klyubin et al. 2002; Wang, Pasternak et al. 2002; Townsend, Shankar et al. 2006), the prime candidate for the neuronal substrate of learning and memory behavior (Bliss and Collingridge 1993). Induced concurrently with synaptic LTP is an increase in the electrical coupling between the dendritic synaptic inputs and the soma, such that a greater proportion of the EPSP survives at the spike trigger zone, resulting in greater action potential output for a given EPSP. This potentiation of EPSP-spike coupling (E-S coupling) provides an additional boost to the efficacy of the EPSP on top of the potentiation (LTP) that occurs at the synapse (Bliss and Lomo 1973). While LTP of synaptic strength is an essential component of memory storage, in all models of learning, memory recall occurs only when spikes are evoked in the neurons participating in a representation. Thus E-S potentiation exerts control over the essential substrate of memory retrieval. Although LTP and E-S potentiation are mechanistically distinct processes, several features during the induction phase are shared. Studies have shown that Abeta impairs the induction, but not maintenance of LTP (Wang, Walsh et al. 2004; Townsend, Shankar et al. 2006), leaving the possibility that Abeta-mediated impairment to memory is not specific to LTP. Nevertheless, focus has centered on pathways central to LTP, while impairment to other forms of plasticity have not been explored. Here we show a mechanism by which Abeta peptides impairs post-tetanic suppression of inhibition, thereby inhibiting E-S potentiation. This impairment to E-S potentiation was occluded by GABAA-receptor, Cannabinoid 1 receptor (CB1R), and muscarinic acetylcholine receptor (mAChR), but not mGluR block. This suggests that the impairment is mediated by mAChR-initiated endocannbinoid signaling. Together, the results provide a mechanism to explain learning and memory impairments in early Alzheimer's disease.
  • 2010 Springer
    Gertz, Morie A.; Rajkumar, S. Vincent.
    Fibril structure and fibrillogenesis -- Imaging of systemic amyloidosis -- Diagnosis and classification -- Pathogenesis of systemic amyloidoses -- Supportive care for amyloidosis -- Assessing response and prognosis in AL amyloidosis -- Localized amyloidosis -- Amyloid heart disease -- Renal amyloidosis -- Primary systemic amyloid neuropathy -- Conventional treatment of amyloidosis -- High-dose therapy in amyloidosis -- Secondary, AA, amyloidosis -- ATTR: diagnosis, prognosis, and treatment -- Other systemic forms of amyloidosis.
  • 2006
    Brown, Robert H.; Pasinelli, Piera; Swash, Michael.
    Status: Not Checked OutLane Catalog Record
  • 2015
    Kılıç, Abdullah; Altıntaş, Ayten; Ekibi, Zeynep Alp ve.
    Status: Not Checked OutLane Catalog Record
    Discusses "houses of healing" established during the Seljuk and Ottoman eras which were visited by the authors. Evaluates these charitable institutions from the perspective of the history of medicine, the history of art, and cultural history. Presents medicine as practiced in the Anatolian Seljuk and Ottoman Empires, was well as their hospitals, followed by coverage of each facility (about 20, of which only two continue as hospitals).
  • 2013 ClinicalKey
    Yentis, S. M.; Hirsch, Nicholas; Ip, James K.; Smith, G. B.
    Building on the success of previous editions, Anaesthesia and Intensive Care A-Z (Fifth edition) remains the most comprehensive single volume source of relevant aspects of pharmacology, physiology, anatomy, physics, statistics, medicine, surgery, general anaesthetic practice, intensive care, equipment, and the history of anaesthesia and intensive care. Originally prepared as essential reading for candidates for the Fellowship of the Royal College of Anaesthetists and similar exams, this fully updated edition will also prove as invaluable as ever for all anaesthetists and critical care phys.
  • 2007
    Sykes, M. K.; Bunker, John P.
    Status: Not Checked OutLane Catalog Record
  • 2009 Springer
    Astuto, Marinella.
  • 2008 Springer
    Gullo, A.
    Advances on critical care -- Airway -- Trauma -- Obstetrics -- Paediatric anaesthesia -- Cardiac arrest -- Infections, sepsis, organ dysfunction -- Perioperative care -- Quality of care in the ICU.
  • 2007 Springer
    Gullo, A.
  • 2006 Springer
    Gullo, A.
  • 2014 Springer
    Gullo, A.
    The APICE 2013 yearbook examines recent advances in various aspects of critical care medicine and highlights the importance of effective communication among researchers, scientists, and clinicians. Among the many topics addressed are trauma care organization, the management of patients with cardiovascular, kidney, and lung disorders, issues relating to severe infections and sepsis, and the humanization of end of life care. The overriding goal of the book is to provide guidance and stimulate further thought on how professional performance in critical care medicine can be improved. Triple B translational research, from the bench to the bedside and back again (via the translation of clinical observations into new research questions), will play a major role in this context, and is particularly discussed in the chapter about sepsis and organ dysfunction. There is no doubt that the transfer of far-reaching and dynamic developments in molecular and cellular biology into clinical practice will be a key component in delivering the care required by individual patients.
  • 2011 Springer
    Gullo, A.
    pt. I. Continuing medical education -- 1. Can I Think what I Read? / Philip D. Lumb -- pt. II. Clinical pharmacology -- 2. Pharmacological Manipulation in ICU / Daniel De Backer, Katia Donadello and Sabino Scolletta -- pt. III. Kidney -- 3. Renal Injury / Vladimir Gašparović, Ivan Gornik -- pt. IV. Ventilation: adult and paediatric -- 4. Respiratory Mechanics: Principles, Utility and Advances / Alysson R. Carvalho, Walter A. Zin -- 5. Capnometry/capnography in Prehospital Cardiopulmonary Resuscitation / Štefek Grmec, Katia Lah and Štefan Mally -- 6. Weaning from Mechanical Ventilation / Irene Cortés Puch, Andrés Esteban -- 7. Ventilatory Strategies in Acute Lung Injury / Edoardo Calderini, Sara Sher and Eleonora Allegritti -- 8. Mechanical Ventilation Beyond the PICU / Giancarlo Ottonello, Alessia Franceschi -- pt. V. Cardiovascular monitoring 9. The Nexfin Monitor--A Totally Non-Invasive Cardiac Output Monitor / Azriel Perel, Wilbert Wesselink and Jos Settels -- 10. Doppler Echocardiography in ICU Patients: Does It Improve Outcome? / Jan Poelaert -- pt. VI. Management of cardiac arrest -- 11. Mild Therapeutic Hypothermia after Cardiac Arrest / Tommaso Pellis, Vincenzo Mione and Willy P. Mercante -- 12. Nasopharyngeal Cooling During Cardiopulmonary Resuscitation / Francesco Fumagalli, Giuseppe Ristagno -- 13. Amplitude Spectrum Area as a Predictor of Successful Defibrillation / Giuseppe Ristagno, Yongqin Li, Antonino Gullo and Joe Bisera -- pt. VII. Advances in experimental and clinical research -- 14. Physiopathology and Severity of Post-Resuscitation Myocardial Dysfunction: Effects of Sodium-Hydrogen Exchanger Isoform-1 (NHE-1) Inhibitors and Erythropoietin / Raúl J. Gazmuri, Iyad M. Ayoub and Jeejabai Radhakrishnan -- 15. Experimental Treatment for Preservation of Mechanically Competent Cardiac Activity Following Cardiac Arrest / Iyad M. Ayoub, Jeejabai Radhakrishnan and Raúl J. Gazmuri -- 16. Erythropoietin Facilitates Return of Spontaneous Circulation and Survival in Victims of Out-of-Hospital Cardiac Arrest / Štefek Grmec, Matej Strand and Raúl J. Gazmuri -- pt. VIII. Infections, sepsis and organ dysfunctions -- 17. Pathophysiology of Resistance amongst Aerobic Gram-negative Bacilli in Particular Acinetobacter Species / Nia Taylor, Luciano Silvestri and Hendrick K.F. Van Saene -- 18. What Have We Learned from the Surviving Sepsis Campaign? / Jean-Louis Vincent, Katia Donadello and Leonardo Gottin -- 19. Source Control / Gabriele Sganga, Valerio Cozza -- 20. Immunoglobulins in Sepsis / Giorgio Berlot, Claudio M. Vassallo and Nicola Busetto -- pt. IX. Perioperative medicine -- 22. Perioperative Medicine--An Introduction / Antonino Gullo, Chiara M. Celestre, Annalaura Paratore and Fortunato Stimoli -- 23. Neuraxial Analgesia for Caesarean and Vaginal Delivery and Childhood Learning Disabilities / Juraj Sprung, Randall Flick and David Warner -- 24. Off-label Drugs in Perioperative Medicine: Clonidine / Cesare Gregoretti, Paolo Pelosi -- pt. X. Spinal cord stimulation -- 25. Cost Effectiveness of Spinal Cord Stimulation in the Management of Severe Angina / Mats Börjesson, Clas Mannheimer -- pt. XI. Neurotrauma -- 26. Clinical Assessment and Diagnostic Procedures in Neurotrauma / Marco Zanello, Matteo Vincenzi and Marco Bandini -- pt. XII. Disaster medicine -- 27. Disaster Preparedness / Francesco Della Corte, Pier Luigi Ingrassia -- 28. Medical Emergency Response in Toxicological Mass Casualty / Pier Luigi Ingrassia, Luca Ragazzoni and Francesco Della Corte -- pt. XIII. Quality of care -- 29. Telemedicine to Improve Care in the Critically Ill / Gastón Murias, Bernat Sales Lluis Blanch -- 30. Professionalism, Quality of Care and Pay-for-Performance Services / Antonino Gullo, Cristina Santonocito, Paolo Murabito and Marinella Astuto.
  • 2012 Springer
    Avital, Shmuel; Ehrenpreis, Eli; Singer, Marc.
    Anal and Rectal Diseases: A Concise Manual provides a succinct reference on the subject for clinicians, including primary care physicians, gastroenterologists, general surgeons, physician's assistants and nurse practitioners. Presented in a consistent structural style that provides both a general summary of individual topics within the field along with additional details to assist those with some background knowledge in the subject area, this handy volume provides information related to the field of anorectal disease in a format that is easily accessible for rapid acquisition of knowledge. Each topic is outlined in a multidisciplinary fashion with the medical, surgical, and pathological aspects clearly detailed in each section. Each section clearly describes the condition with up-to-date management guidelines and precious clinical pearls. The volume features high quality illustrations in the form of elegant hand drawn figures, tables, photographs of physical findings, endoscopic finds and radiographs. The clinical photographs and x-rays will be of great value to gastroenterologists whose specialty is not coloproctology. Chapters on computerized tomographic colography (virtual colonoscopy) and others cover the newer technologies employed for diagnostic purposes in these diseases. Anal and Rectal Diseases: A Concise Manual provides clinicians with a tool for rapid consultation for direct patient care and management.
  • 2014 Springer
    Abcarian, Herand.
    1. Epidemiology, Incidence and Prevalence of Fistula in Ano / Richard L. Nelson and Herand Abcarian -- 2. Applied Anatomy / Russell K. Pearl -- 3. Relationship of Abscess to Fistula / Hernand Abcarian -- 4. Classification and Treatment of Anorectal Infections / Adrian E. Ortega and Kyle G. Cologne -- 5. Clinical Assessment of Anal Fistulas / Herand Abcarian -- 6. Clinical Assessment and Imaging Modalities of Fistula in Ano / Kyle G. Cologne, Juan Antonio Villanueva-Herrero, Enrique Montaño-Torres, and Adrian E. Ortega -- 7. Classification and Management Strategies / Herand Abcarian -- 8. Seton (Loose, Cutting, Chemical) / Varnsi R. Velchuru -- 9. Fistulotomy and Lay Open Technique / Philip Tozer and Robin K.S. Phillips -- 10. Fistulectomy with Primary Sphincter Reconstruction / Alexander Herold -- 11. Fibrin Sealant / Jose R. Cintron -- 12. Biologic Fistula Plugs / Samuel Eisenstein and Alex Jenny Ky -- 13. Synthetic Fistula Plug / Alex Jenny Ky, Michael Polcino, and Alero T. Nanna -- 14. Endorectal Advancement Flap / Christine C. Jensen -- 15. Dermal Advancement Flap / Christine C. Jensen -- 16. Ligation of Intersphincteric Fistula Tract (LIFT) / Ariane M. Abcarian -- 17. Video-Assisted Anal Fistula Teatment (VAAFT) / Piercarlo Meinero and Lorenzo Mori -- 18. Stem Cell Application in Fistula Disease / Damian Garcia-Olmo and Hector Guadalajara-Labajo -- 19. Crohn's Disease / James Fleshman and Rachel Tay -- 20. Tuberculosis Fistula / Pravin Jaiprakash Gupta -- 21. Fistula Surgery in the Era of Evidence-Based Medicine / Richard L. Nelson and Hernand Abcarian -- 22. Causes of Operative Failure / Mohammad Ali Abbass and Maher Aref Abbas 23. Recurrence/Persistence After Fistula Teatmcnt: What Next? / Hernand Abcarian.
  • 2007 Springer
    Benedetti, F.; Stein, Christoph.
    Part I. Introduction -- Peripheral and central mechanism of pain generation / H.G. Schaible -- Part II. Drugs in clinical use -- Opioids / C. Zöllner, C. Stein -- Antipyretic analgesics: nonsteroidal antiinflammatory drugs, selective COX-2 inhibitors, paracetamol and pyrazolionones / B. Hinz, K. Brune -- Local anesthetics / R. Yanagidate, G.R. Strichartz -- Serotonin receptor ligands: treatments of acute migraine and cluster headache / P.J. Goadsby -- Anti-convulsants and anti-depressants / A.H. Dickenson, J. Ghandehari -- Part III. Compounds in preclinical development -- Neuropeptide and kinin antagonists / R. G. Hill, K.R. Oliver -- Glutamate receptor ligands / V. Neugebauer -- Adrenergic and cholinergic compounds / R. D. Sanders, M. Maze -- Cannabinoids and pain / I.J. Lever, A.S.C. Rice -- Part IV. Future targets in analgesia research -- Adenosine and ATP receptors / J. Sawynok -- Ion channels in analgesia research / J.N. Wood -- Protein kinases as potential targets for the treatment of pathological pain / R. R. Ji, Y. Kawasaki, Z. Y. Zhuang, Y.R. Wen, Y.Q. Zhang -- Part V. Pain Management beyond pharmacotherapy -- Placebo and endogenous mechanisms of analgesia / F. Bededetti -- Limitations of pharmacotherapy: behavioral approaches to chronic pain / H. Flor, M. Diers -- Subject index.
  • 2012 Future Med
    Porecca, Frank.
    Analgesics for cancer pain / Tamara King & Frank Porreca -- Cancer pain assessment and consensus guidelines / Brian Wilhelmi & Paul J. Christo -- Role of step 2 opioid analgesics in mild-to-moderate pain intensity treatment / Wojciech Leppert -- Opioid analgesics for severe cancer pain / Phillip Good & Janet Hardy -- Alternative opioids and administration routes / Mellar P. Davis -- Adjuvant analgesics for cancer pain / Russell K. Portenoy & Ebtesam Ahmed -- Analgesics for breakthrough pain / Sebastiano Mercadante -- Emerging analgesics and future directions : targeting bone remodeling / Flaminia Coluzzi -- Emerging analgesics and future directions : targeting neuroplasticity / Alysia N. Lozano-Ondoua & Todd W. Vanderah -- Index.
  • 2013 Wiley
    Fischer, János; Ganellin, C. R.; Rotella, David P.
    General Aspects. Pioneer and Analogue Drugs / Janos Fischer, C Robin Ganellin, David P Rotella -- Competition in the Pharmaceutical Drug Development / Christian Tyrchan, Fabrizio Giordanetto -- Metabolic Stability and Analogue-Based Drug Discovery / Amit S Kalgutkar, Antonia F Stepan -- Use of Macrocycles in Drug Design Exemplified with Ulimorelin, a Potential Ghrelin Agonist for Gastrointestinal Motility Disorders / Mark L Peterson, Hamid Hoveyda, Graeme Fraser, Eric Marsault, Rene Gagnon -- Drug Classes. The Discovery of Anticancer Drugs Targeting Epigenetic Enzymes / A Ganesan -- Thienopyridyl and Direct-Acting P2Y Receptor Antagonist Antiplatelet Drugs / Joseph A Jakubowski, Atsuhiro Sugidachi -- Selective Estrogen Receptor Modulators / Amarjit Luniwal, Rachael Jetson, Paul Erhardt -- Discovery of Nonpeptide Vasopressin V2 Receptor Antagonists / Kazumi Kondo, Hidenori Ogawa -- The Development of Cysteinyl Leukotriene Receptor Antagonists / Peter R Bernstein -- Case Studies. The Discovery of Dabigatran Etexilate / Norbert Hauel, Andreas Clemens, Herbert Nar, Henning Priepke, Joanne van Ryn, Wolfgang Wienen -- The Discovery of Citalopram and Its Refinement to Escitalopram / Klaus P Bogeso, Connie Sanchez -- Tapentadol : From Morphine and Tramadol to the Discovery of Tapentadol / Helmut Buschmann -- Novel Taxanes: Cabazitaxel Case Study / Herve Bouchard, Dorothee Semiond, Marie-Laure Risse, Patricia Vrignaud -- Discovery of Boceprevir and Narlaprevir: A Case Study for Role of Structure-Based Drug Design / Srikanth Venkatraman, Andrew Prongay, George F Njoroge -- A New-Generation Uric Acid Production Inhibitor: Febuxostat / Ken Okamoto, Shiro Kondo, Takeshi Nishino.
  • Google Books
    Also available: Print – 1998
  • 2007 Springer
    Zuur, Alain F.; Ieno, Elena N.; Smith, Graham M.
  • 2007
    Pincus, Zachary S.
    Status: Not Checked OutLane Catalog Record
  • 2015 Springer
    Tatsuno, Masami.
    Since information in the brain is processed by the exchange of spikes among neurons, a study of such group dynamics is extremely important in understanding hippocampus dependent memory. These spike patterns and local field potentials (LFPs) have been analyzed by various statistical methods. These studies have led to important findings of memory information processing. For example, memory-trace replay, a reactivation of behaviorally induced neural patterns during subsequent sleep, has been suggested to play an important role in memory consolidation. It has also been suggested that a ripple/sharp wave event (one of the characteristics of LFPs in the hippocampus) and spiking activity in the cortex have a specific relationship that may facilitate the consolidation of hippocampal dependent memory from the hippocampus to the cortex. The book will provide a state-of-the-art finding of memory information processing through the analysis of multi-neuronal data. The first half of the book is devoted to this analysis aspect. Understanding memory information representation and its consolidation, however, cannot be achieved only by analyzing the data. It is extremely important to construct a computational model to seek an underlying mathematical principle. In other words, an entire picture of hippocampus dependent memory system would be elucidated through close collaboration among experiments, data analysis, and computational modeling. Not only does computational modeling benefit the data analysis of multi-electrode recordings, but it also provides useful insight for future experiments and analyses. The second half of the book will be devoted to the computational modeling of hippocampus-dependent memory.
  • 2012 Wiley
    Jiskoot, Wim; Mahler, Hanns-Christian.
    The critical need for robust assays for quantitation and characterization of aggregates of therapeutic proteins -- Separation based analytical methods for measuring protein aggregation -- Laser light scattering-based techniques used for the characterization of protein therapeutics -- Online detection methods and emerging techniques for soluble aggregates in protein pharmaceuticals -- Analytical methods to measure sub-visible particulates -- Detection of visible particles in parenteral products -- Characterization of aggregates and particles using emerging techniques -- Ultraviolet absorption spectroscopy -- Fluorescence spectroscopy to characterize protein aggregates and particles -- Infrared spectroscopy to characterize protein aggregates -- Raman microscopy for characterization of particles -- Microscopic methods for particle characterization in protein pharmaceuticals -- Comparison of methods for soluble aggregate detection and size characterization -- Protein purification and its relation to protein aggregation and particles -- Formulation development and its relation to protein aggregation and particles.
  • 2011 ScienceDirect
    Morris, Andrew Paul; Zeggini, Eleftheria.
    According to the National Institute of Health, a genome-wide association study is defined as any study of genetic variation across the entire human genome that is designed to identify genetic associations with observable traits (such as blood pressure or weight), or the presence or absence of a disease or condition. Whole genome information, when combined with clinical and other phenotype data, offers the potential for increased understanding of basic biological processes affecting human health, improvement in the prediction of disease and patient care, and ultimately the realization of the promise of personalized medicine. In addition, rapid advances in understanding the patterns of human genetic variation and maturing high-throughput, cost-effective methods for genotyping are providing powerful research tools for identifying genetic variants that contribute to health and disease. This burgeoning science merges the principles of statistics and genetics studies to make sense of the vast amounts of information available with the mapping of genomes. In order to make the most of the information available, statistical tools must be tailored and translated for the analytical issues which are original to large-scale association studies. This book will provide researchers with advanced biological knowledge who are entering the field of genome-wide association studies with the groundwork to apply statistical analysis tools appropriately and effectively. With the use of consistent examples throughout the work, chapters will provide readers with best practice for getting started (design), analyzing, and interpreting data according to their research interests. Frequently used tests will be highlighted and a critical analysis of the advantages and disadvantage complimented by case studies for each will provide readers with the information they need to make the right choice for their research.
  • 2014 CRCnetBASE
    Wang, Guanyu.
    Food intake and energy metabolism -- Glucose homeostasis -- Optimal glucose homeostasis -- Bistability as a fundamental phenomenon -- Biomolecular network -- P13K-AKT-TOR pathway -- Diseases related to metabolism -- Mathematical modeling of the P13K-AKT-TOR Pathway -- Fundamental decomposition -- Normal phenotype -- Disease phenotypes -- Tao of diseases.
  • 2007
    Shoukri, M. M.; Chaudhary, Mohammad A.
    Status: Not Checked OutLane Catalog Record
  • 2006
    Gordon, Michael Douglas.
    Status: Not Checked OutLane Catalog Record
  • 2007 CRCnetBASE
    Sater, Amy Katherine; Whitman, Malcolm.
  • v. 1-3, 1984 CRCnetBASE
    Milliken, George A.; Johnson, Dallas E.
    v. 1. Designed experiments -- v. 2. Nonreplicated experiments -- v. 3. Analysis of covariance
  • 2010 Atypon
    Ayres, Fábio José; Desautels, J. E. Leo; Rangayyan, Rangaraj M.
    The presence of oriented features in images often conveys important information about the scene or the objects contained; the analysis of oriented patterns is an important task in the general framework of image understanding. As in many other applications of computer vision, the general framework for the understanding of oriented features in images can be divided into low- and high-level analysis. In the context of the study of oriented features, low-level analysis includes the detection of oriented features in images; a measure of the local magnitude and orientation of oriented features over the entire region of analysis in the image is called the orientation field. High-level analysis relates to the discovery of patterns in the orientation field, usually by associating the structure perceived in the orientation field with a geometrical model. This book presents an analysis of several important methods for the detection of oriented features in images, and a discussion of the phase portrait method for high-level analysis of orientation fields. In order to illustrate the concepts developed throughout the book, an application is presented of the phase portrait method to computer-aided detection of architectural distortion in mammograms.
  • 2010 Springer
    Grün, Sonja; Rotter, Stefan.
    Part I: Basic Spike Train Statistics -- 1 Stochastic Models of Spike Trains -- 2 Estimating the Firing Rate -- 3 Analysis and Interpretation of Interval and Count Variability in Neural Spike Trains -- 4 Processing of Phase-Locked Spikes and Periodic Signals -- Part II: Pairwise Comparison of Spike Trains -- 5 Pair-Correlation in the Time and Frequency Domain -- 6 Dependence of Spike-Count Correlations on Spike-Train Statistics and Observation Time Scale -- 7 Spike Metrics -- 8 Gravitational Clustering -- Part III: Multiple-Neuron Spike Patterns -- 9 Spatio-Temporal Patterns -- 10 Unitary Event Analysis -- 11 Information Geometry of Multiple Spike Trains -- 12 Higher-Order Correlations and Cumulants -- Part IV: Population-Based Approaches -- 13 Information Theory and Systems Neuroscience -- 14 Population Coding -- 15 Stochastic Models for Multivariate Neural Point Processes: Collective Dynamics and Neural Decoding -- Part V: Practical Issues -- 16 Simulation of Stochastic Point Processes with Defined Properties -- 17 Generation and Selection of Surrogate Methods for Correlation Analysis -- 18 Bootstrap Tests of Hypotheses -- 19 Generating Random Numbers -- 20 Practically Trivial Parallel Data Processing in a Neuroscience Laboratory -- Index.
  • 2008 CRCnetBASE
    Tadeo, José L.
    Pesticides: classification and properties / José L. Tadeo, Consuelo Sánchez-Brunete, Lorena González -- Sample handling of pesticides in food and environmental samples / Esther Turiel, Antonio Martín-Esteban -- Analysis of pesticides by chromatographic techniques coupled with mass spectrometry / Simon Hird -- Immunoassays and biosensors / Jeanette M. Van Emon ... [et al.] -- Quality assurance / Árpád Ambrus -- Determination of pesticides in food of vegetal origin / Frank J. Schenck, Jon W. Wong -- Determination of pesticides in food of animal origin / Antonia Garrido Frenich, Jose Luis Martinez, Adrian Covaci -- Determination of pesticides in soil / Consuelo Sánchez-Brunete, Beatriz Albero, José L. Tadeo -- Determination of pesticides in water / Jay Gan, Svetlana Bondarenko -- Sampling and analysis of pesticides in the atmosphere / Maurice Millet -- Levels of pesticides in food and food safety aspects / Kit Granby ... [et al.] -- Monitoring of pesticides in the environment / Ioannus Konstantinou ... [et al.].
  • 2008
    Ching, Wendy.
    Status: Not Checked OutLane Catalog Record
  • 2011
    McElwain, Mark Allan; Kingsley, David M.; Nusse, Roeland; Schneider, David; Talbot, William S.
    Only a few signaling pathways control the majority of biological processes throughout animal development and homeostasis, indicating that each pathway regulates multiple processes. The Wnt family of secreted ligands is one interesting and important example of this paradigm. Evidence abounds that Wnt signaling impacts numerous biological events including embryonic patterning, stem cell self- renewal, cell proliferation, and tissue regeneration. While only a few Wnt proteins have been extensively characterized, it is likely that each family member signals to control a variety of critical biological processes; therefore, it is clear that by understanding the signaling mechanism used by a single Wnt protein, we can understand how many aspects of biology are regulated. WntD is one of 7 Wnt homologs encoded by the Drosophila genome. While most of these Wnt proteins likely signal through a pathway dependent on the [Beta]-catenin homolog Armadillo (Arm), WntD very likely utilizes an Arm-independent mechanism to control embryonic dorsal/ventral (D/V) patterning, migration of the primordial germ cells (PGC) to the embryonic gonad, and the innate immune response. It is therefore of great interest to identify genes involved in this signal transduction pathway and better characterize the effect WntD has on these important biological processes. To this end, a suppressor/enhancer deficiency screen based upon the role of WntD in D/V patterning was previously performed in the laboratory. From this screen, 30 strong candidates for suppressors and 13 strong candidates for enhancers were identified. Here, I present further characterization of two candidate WntD pathway members identified in the screen: Fz4, a likely WntD receptor and Dcerk, a lipid kinase. I show by both in vitro and in vivo assays that both Fz4 and Dcerk function in the WntD signal transduction pathway, and present evidence suggesting that this WntD-Fz4-Dcerk signaling cassette is utilized during both D/V patterning and PGC migration, yet another instance of a single signaling cascade mediating multiple developmental events. Interestingly, I show that both of these novel WntD signal transducers appear to act redundantly with a homologous protein: in both D/V patterning and PGC migration, WntD likely signals through Fz3 and Fz4 receptors to activate the lipid kinases Dcerk and Dmulk. I further show, in collaboration with the Saba Laboratory at Children's Hospital Oakland Research Institute, that these kinases are necessary for wild-type ceramide-1-phosphate (C1P) levels in the adult, and either is sufficient to increase embryonic C1P levels, suggesting that both Dcerk and Dmulk are bona fide ceramide kinases. My data linking WntD-ceramide kinase signaling to PGC migration is consistent with a model in which WntD signaling is responsible for generation of optimal levels of embryonic C1P, which is likely to be the long-undiscovered substrate that is formed into a gradient by the lipid phosphate phosphatases encoded by Wunen and Wunen2. Future experiments will be required to further test this model. Importantly, these results may suggest a mechanism for the regulation of a broad range of migratory cell types, including other cells that migrate to generate a specific tissue or organ during embryonic development, and immune cells that must travel long distances to fight off infections.
  • 2008 Springer
    Sobolev, Boris; Kuramoto, Lisa.
  • 2007 CRCnetBASE
    Kintz, Pascal.
    Drug incorporation into hair / Robert Kronstrand and Karen Scott -- Passive exposure, decontamination procedures, cutoffs, and bias: pitfalls in the interpretation of hair analysis results for cocaine use / David A. Kidwell and Frederick P. Smith -- Opioids testing in hair / Michel Yegles and Robert Wennig -- Hair analysis for cocaine / Carmen Jurado -- Determination of cannabinoids in human hair / Michael Uhl -- Amphetamine determination in hair / Vincent Cirimele -- Pharmaceuticals in hair / Marjorie Cheze, Marc Deveaux, Gaelle Duffort, Francis Billault, and Gilbert Pepin -- Screening strategies in hair analysis on drugs / Hans Sachs -- Clinical applications of hair analysis / Simona Pichini, Oscar Garcia-Algar, and Rafael de la Torre -- Hair in postmortem toxicology / Robert Kronstrand and Henrik Druid -- Detection of doping agents in human hair / Pascal Kintz -- Applications of hair in drug-facilitated crime evidence / Marion Villain -- Application of hair in driving-license regranting / Manfred R. Moeller, Hans Sachs, and Fritz Pragst -- Alcohol markers in hair / Fritz Pragst and Michel Yegles -- Workplace drug testing using hair samples / Thomas Cairns, Michael Schaffer, and Virginia Hill -- Metals / Jean-Pierre Goulle.
  • 2012 Wiley
    Caroli, Sergio; Záray, Gyula.
    Part I Exploring fundamentals -- Good clinical practice principles: legal background and applicability / Umberto Filibeck, Angela Del Vecchio, and Fabrizio Galliccia -- Clinical chemistry and the quest for quality / Sergio Caroli -- Uncertainty in clinical chemistry measurements including preanalytical variables / Marit Sverresdotter Sylte, Tore Wentzel-Larsen, and Bjorn J. Bolann -- The role and significance of reference values in the identification and evaluation of trace elements from diet / Pietro Apostoli and Maria Cristina Ricossa -- Sample collection, storage, and pretreatment in clinical chemistry / Andrew Taylor -- Metal toxicology in clinical, forensic, and chemical pathology / Jose A. Centeno [and others] -- Part II Selected applications -- Elemental speciation in clinical sciences / Douglas M. Templeton -- The role of analytical chemistry in the safety of drug therapy / Sandor Gorog -- Analytical techniques and quality control of pharmaceuticals / Fedele Manna, Francesca Rossi, and Rossella Fioravanti -- Detection of drugs in biological fluids for antidoping control / Sabina Strano Rossi and Marcello Chiarotti -- The applicability of plasma-based techniques to biological monitoring / Ilse Steffan and Goran Vujicic -- Atomic spectrometric techniques for the analysis of clinical samples / Pilar Bermejo Barrera, Antonio Moreda Pineiro, and Maria del Carmen Barciela Alonso -- Applications of ICP-MS in human biomonitoring studies / Peter Heitland and Helmut D. Koster -- Molybdenum in biological samples and clinical significance of serum molybdenum / Munehiro Yoshida -- Application of organometallic speciation in clinical studies / Bin He [and others] -- Biosensors for drug analysis / Daniela Deriu and Franco Mazzei -- Bioimaging of metals and proteomic studies of clinical samples by laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) / J. Sabine Becker and J. Susanne Becker -- Applications of LC-MS/MS in clinical laboratory diagnostics / Uta Ceglarek, Georg Martin Fiedler, and Joachim Thiery -- Metabolomics using UPLC/HPLC-tandem mass spectrometry in diagnosis and research of inherited metabolic diseases / Willem Kulik and Andre B.P. van Kuilenburg -- Biomarkers of oxidative stress in plasma and urine / Papasani V. Subbaiah -- The use of x-ray techniques in medical research / Imre Szaloki, Gyula Zaray, and Norbert Szoboszlai -- Part III Future trends -- A new tool based on the use of stable isotopes and isotope pattern deconvolution (IPD)-ICP-MS for nutritional and clinical studies / Hector Gonzalez Iglesias, Maria Luisa Fernandez-Sanchez, and Alfredo Sanz-Medel -- Breath analysis: analytical methodologies and clinical applications / Alessio Ceccarini [and others] -- Proteo-metabolomic strategies in the future of drug development / Uwe Christians [and others] -- Basics in laboratory medicine: past, present, and future / Lorand A. Debreczeni, Anna Kovacsay, and Sandor Nagy.
  • 2011 Springer
    Katoch, Rajan.
    Advances in biochemistry now allow us to control living systems in ways that were undreamt of a decade ago. This volume guides researchers and students through the full spectrum of experimental protocols used in biochemistry, plant biology and biotechnology.
  • 2015 ScienceDirect
    Cole, James L.
    Analytical Ultracentrifugation, the latest volume in Methods in Enzymology, focuses on analytical ultracentrifugation. The scope of this technique has greatly expanded in recent years due to advances in instrumentation, algorithms and software. This volume describes the latest innovations in the field and in the applications of analytical ultracentrifugation in the analysis of macromolecules, macromolecular assemblies, and biopharmaceuticals.
  • 2015 Wiley
    Chen, Dongmei; Moulin, Bernard; Wu, Jianhong.
    Introduction to analyzing and modeling spatial and temporal dynamics of infectious diseases / Dongmei Chen, Bernard Moulin, Jianhong Wu -- Modeling the spread of infectious diseases : a review / Dongmei Chen -- West Nile virus : a narrative from bioinformatics and mathematical modeling studies / U.S.N. Murty, Amit Kumar Banerjee and Jianhong Wu -- West Nile virus risk assessment and forecasting using statistical and dynamical models / Ahmed Abdelrazec, Yurong Cao, Xin Gao, Paul Proctor, Hui Zheng, and Huaiping Zhu -- Using mathematical modeling to integrate disease surveillance and global air transportation data / Julien Arino and Kamran Khan -- Mathematical modeling of malaria models with spatial effects / Daozhou Gao and Shigui Ruan -- Avian influenza spread and transmission dynamics / Lydia Bourouiba, Stephen Gourley, Rongsong Liu, John Takekawa, and Jianhong Wu -- Analyzing the potential impact of bird migration on the global spread of H5N1 avian influenza (2007-2011) using spatio-temporal mapping methods / Heather Richardson and Dongmei Chen -- Cloud computing-enabled cluster detection using a flexibly shaped scan statistic for real-time syndromic surveillance / P. Belanger and K. Moore -- Mapping the distribution of malaria : current approaches and future directions / L.R. Johnson, K.D. Lafferty, A. McNally, E. Mordecai, K. Paaijmans, S. Pawar, S.J. Ryan -- Statistical modeling of spatio-temporal infectious disease transmission / Rob Deardon, Xuan Fang and Grace Pui Sze Kwong -- Spatio-temporal dynamics of schistosomiasis in China : bayesian-based geostatistical analysis / Zhi-Jie Zhang -- Spatial analysis and statistical modeling of 2009 H1N1 pandemic in the greater Toronto area / Frank Wen, Dongmei Chen, Anna Majury -- West Nile virus mosquito abundance modeling using a non-stationary spatio-temporal geostatistics / Eun-Hye Yoo, Dongmei Chen, Curtis Russel -- Spatial pattern analysis of multivariate disease data / Cindy X. Feng and Charmaine Dean -- The zoonosismags project (part 1) : population-based geosimulation of zoonoses in an informed virtual geographic environment / Bernard Moulin, Mondher Bouden, Daniel Navarro -- Zoonosismags project (part 2) : complementarity of a rapid-propotyping tool and of a full-scale geosimulator for population-based geosimulation of zoonoses / Bernard Moulin, Daniel Navarro, Dominic Marcotte, Said Sedrati -- Web-mapping and behaviour pattern extraction tools to assess lyme disease risk for humans in peri-urban forests / Hedi Haddad, Bernard Moulin, Franck Manirakiza Christelle Maha, Vincent Godard and Samuel Mermet -- An integrated approach for communicable disease geosimulation based on epidemiological, human mobility and public intervention models / Hedi Haddad, Bernard Moulin, Marius Thariault -- Smartphone trajectories as data sources for agent-based infection spread modeling / M.R. Friesen and R.D. McLeod.
  • 2013
    Im, Jin Woo; Brandeau, Margaret L.; Shachter, Ross D.; Trafton, Jodie A.
    Using U.S. Department of Veterans Affairs (VA) records, this dissertation explores the staffing mix in substance use disorder treatment programs (SUDTPs) and the effectiveness of the current clinical practice guideline in reducing suicide risk associated with opioid therapy. The VA treats a large number of Veterans diagnosed with substance use disorders (SUDs) in four types of specialized SUDTPs at an annual cost of more than $350 million. The staffing mixes were not significantly different from 2001 to 2003, the years under review. However, given differences in treatment focus and provided services, the four types of SUDTPs may require different staffing mixes. We demonstrate how cost-effective staffing mixes for each type of VA SUDTP can be defined empirically. We derive prediction functions for benefits and costs based on patients' treatment outcomes at VA SUDTPs nationally from 2001 to 2003, and use them to formulate optimization problems to determine recommended staffing mixes that maximize net benefits per patient for four types of SUDTPs while conforming to limits of current practice. Compared to the actual staffing mixes in 2001-2003, the recommended staffing mixes would lower treatment costs while improving patient outcomes. We also introduce an approach to building a decision support system for staffing each type of SUDTP reflecting the dynamics of effectiveness and costs associated with the staffing changes. Compared to the actual staffing mixes, the staffing mixes suggested by the staffing decision support system are expected to treat significantly more Veteran patients under the existing staffing budget while improving patient outcomes. We also examine associations between adherence to guideline recommendations and the risk of suicide attempt based on Veterans Health Administration (VHA) records. Opioid therapy is often provided to reduce chronic pain in at-risk patients. Unfortunately, available opioid medications have been also used as a means for attempting suicide. In 2010, the VHA and the Department of Defense released a jointly developed clinical practice guideline (CPG) to reduce the risk of adverse events such as suicide attempt in patients prescribed opioids, primarily based on expert consensus. We conduct multivariate mixed-effects logistic regression analyses to define the associations between facility-level CPG adherence rates and risk of suicide attempt while controlling for the associations between individual-level delivery of CPG-based services and the risk of suicide attempt. Major findings include the following: suicide attempts were negatively associated with facility-level adherence rates for both consistent urine drug screenings and follow-up appointments, and were positively associated with facility-level risky sedative co-prescription rates.
  • 2010 Karger
    Ring, Johannes.
    History and epidemiology -- History and classification of anaphylaxis -- Epidemiology of anaphylaxis -- Mechanisms -- T-cell response to allergens -- Anaphylaxis: mechanisms of mast cell activation -- Kinins, airway obstruction, and anaphylaxis -- Role for basophils in systemic anaphylaxis -- Human cardiac mast cells in anaphylaxis -- Diagnosis and clinical symptomatology -- Mastocytosis -- In vitro diagnosis of anaphylaxis -- Allergens and elicitors -- Insect venoms -- Classification and pathophysiology of radiocontrast media hypersensitivity -- Analgesics -- Anaphylaxis to general anesthetics -- Anaphylactic reactions to local anesthetics -- Treatment and prevention -- Anaphylaxis: acute treatment and management -- Epinephrine (adrenaline) in anaphylaxis.
  • 2011 Springer
    Castells, Mariana C.
    Definition and criteria for the diagnoses of anaphylaxis -- An epidemiological approach to reducing the risk of fatal anaphylaxis -- Pathophysiology and organ damage in anaphylaxis -- Mast cells: effector cells of anaphylaxis -- Basophils in anaphylaxis -- Protease mediators of anaphylaxis -- Aspirin and NSAID reactions: diagnosis, pathophysiology, and management -- IgE-dependent and independent effector mechanisms in human and murine anaphylaxis -- Food-induced anaphylaxis -- Antibiotic-induced anaphylaxis -- Anaphylaxis during radiological procedures and in the peri-operative setting -- Hymenoptera-induced hypersensitivity reactions and anaphylaxis -- Idiopathic anaphylaxis -- Exercise-induced anaphylaxis and food-dependent exercise-induced anaphylaxis -- Mastocytosis and mast cell activation syndromes presenting as anaphylaxis -- Anaphylaxis in mastocytosis -- Flushing and urticarial syndromes presenting as anaphylaxis -- Pharmacologic management of acute anaphylaxis -- Drug desensitizations in the management of allergy and anaphylaxis to chemotherapeutic agents and monoclonal antibodies -- Rapid desensitizations for antibiotic-induced hypersensitivity reactions and anaphylaxis -- Induction of tolerance for food-induced anaphylaxis -- Management of anaphylaxis: relevance of causes and future trends in treatment.
  • 2011 Springer
    Chan, Kwan-Leung; Veinot, John P.
    General anatomy of the heart in the chest -- Age-related cardiac changes -- Aortic valve -- Mitral valve -- Tricuspid and pulmonary valve -- Cardiomyopathies -- Ischemic heart disease -- Right ventricular diseases -- Diseases of the aorta -- Pericardial diseases -- Prosthetic heart valves -- Infective endocarditis and related conditions -- Neoplasm, cardiac tumor -- Congenital heart disease -- Cardiac source of embolism -- Assessment of diastolic function -- Cardiac involvement by systemic diseases -- Interventional procedures.
  • 2009 Thieme
    Alberstone, Cary D.; Benzel, Edward C.
    Development and developmental disorders -- Neuroembryology -- Regional anatomy and related syndromes -- Peripheral nerves -- Plexuses -- Nerve roots and spinal nerves -- Spinal cord -- Brainstem -- Cranial nerves -- Cerebellum -- Thalamus -- Hypothalamus -- Basal ganglia -- Limbic system -- Cerebral cortex -- System-based anatomy and differential diagnosis -- Somatosensory system -- Visual system -- Auditory system -- Ocular motor system -- Motor system -- Autonomic nervous system -- Consciousness -- Fluid-system anatomy and function -- Vascular system -- Cerebrospinal fluid.
  • 2010 Springer
    Skandalakis, John Elias; Staley, C. A.; Wood, William C.
  • 2014 Springer
    Di Marino, Vincent; Lepidi, Hubert.
    "This eagerly awaited book offers a unique, comprehensive scientific study of the anatomy of the organ of female sexual pleasure. The authors use macroscopic and microscopic research to guide the reader from the glans, the visible part of the clitoris, where they explore the impressive sensory corpuscles, to the hidden roots of the bulbo-clitoral organ. They show its complexity, its exact location within the external genitalia and its intimate relationship with the urethro-vaginal pyramid. They also remind us that throughout history there has been a failure to understand this organ, and explain that this misunderstanding remains the cause of persistent excisions, criminal mutilating practices that have not yet been eradicated. Using extensive iconography, they demonstrate throughout this book that the bulbo-clitoral organ is an exceptional natural treasure that every woman possesses and that every man should know well."--Publisher's website.
  • 2008 Springer
    Endō, Hideki; Frey, R.
    Head anatomy of male and female Mongolian gazelle - a striking example of sexual dimorphism / R. Frey ... [et al.] -- Anatomical peculiarities of the vocal tract in felids / G.E. Weissengruber ... [et al.] -- The anatomical foundation for multidisciplinary studies of animal limb function : examples from dinosaur and elephant limb imaging studies / J.R. Hutchinson ... [et al.] -- Locomotion-related femoral trabecular architectures in primates - high resolution computed tomographies and their implications for estimations of locomotor preferences of fossil primates / H. Scherf -- Three-dimensional imaging of the manipulating apparatus in the lesser panda and the giant panda / H. Endo ... [et al.] -- Using CT to peer into the past : 3D visualization of the brain and ear regions of birds, crocodiles, and nonavian dinosaurs / L.M. Witmer ... [et al.] -- Evolutionary morphology of the autonomic cardiac nervous system in non-human primates and humans / T. Kawashima and H. Sasaki.
  • 2007
    Clemente, Carmine D.
    Status: Not Checked OutLane Catalog Record
  • 2015 Springer
    Hanna, Amgad S.
    Upper Body Nerves: Supraclavicular Brachial Plexus -- Infraclavicular Brachial Plexus -- Musculocutaneous Nerve -- Median Nerve -- Ulnar Nerve -- Axillary Nerve -- Radial Nerve -- Suprascapular Nerve -- Long Thoracic and Thoracodorsal Nerves -- Intercostal Nerves. Lower Body Nerves: Lumbosacral Plexus -- Femoral Nerve -- Lateral Femoral Cutaneous Nerve -- Sciatic Nerve Technical Notes.
  • 2007
    Edell, Dean.
    Status: Not Checked OutLane Catalog Record
  • 2014 Wiley
    Ellis, Harold; Lawson, Andrew.
    Part 1. The respiratory pathway, lungs, thoracic wall and diaphragm -- part 2. The heart and great veins of the neck -- part 3. The vertebral canal and its contents -- part 4. The peripheral nerves -- part 5. The autonomic nervous system -- part 6. The cranial nerves -- part 7. Miscellaneous zones of interest -- part 8. The anatomy of pain.
  • 1982-
    Hollinshead, W. Henry.
    Status: Not Checked OutLane Catalog Record
    v.1, The head and neck ; v. 3. The back and limbs.
  • 2007
    Enders, George C.; Klein, Robert M.
    Status: Not Checked OutLane Catalog Record
  • 2010
    Enders, George C.; Klein, Robert M.
    Status: Not Checked OutLane Catalog Record
  • 2011
    Markel, Howard.
    The astonishing account of the decades-long cocaine use of Sigmund Freud and William Halsted. The author discusses the physical and emotional damage caused by the constant use of the then-heralded wonder drug, and of how each man ultimately changed the world in spite of it--or because of it.
  • 2006
    Jamieson, Glyn G.
    Status: Not Checked OutLane Catalog Record
  • 2011
    Melillo, Stephanie Marie; Hadly, Elizabeth Anne; Haile-Selassie, Yohannes; Klein, Richard G.
    Striding bipedalism is a mode of locomotion that defines our lineage. Bipedality freed the hands, arms and shoulders from the mechanical constraints of locomotion, an evolutionary innovation that has had an obvious impact on our species' fitness. As I will discuss in this dissertation, the shoulder blade (scapula) is shaped to optimize use of the upper limb in certain positions. Our closest living relatives (chimpanzees and gorillas) possess adaptations that likely increase efficiency in overhead use of the arms, as in forearm suspension or vertical climbing. The modern human shoulder, on the other hand, lacks such adaptations. This difference may reflect an evolutionary change in shape that occurred as our ancestors transitioned to a terrestrial way of life and became increasingly dexterous, eventually losing ancestral adaptations. On the other hand, recent discoveries suggest our lineage may have never possessed adaptations to suspension. Fossils from the shoulder of our early human ancestors are scarce. A recently discovered partial skeleton from Woranso-Mille (Afar Depression, Ethiopia), KSD-VP-1/1, preserves the oldest and most complete scapula of an adult Australopithecus afarensis individual. The intended contribution of this dissertation is to provide a comparative description of the new scapula (KSD-VP-1/1g) and to detail its implications for our understanding of anatomy and adaptation in the Australopithecus shoulder, and the evolutionary history of the modern human shoulder more generally.
  • Gray, Henry; Lewis, Warren H.
    Also available: Print – 1918
  • Jackson Lab
    Cook, Margaret J.
    Also available: Print – 2005/1965
  • 2007 Springer
    Baldock, Richard; Burger, Albert G.; Davidson, Duncan.
    Existing anatomy ontologies for human, model organisms and plants -- Anatomical ontologies for model organisms : the fungi and animals / Jonathan Bard -- Plant structure ontology (PSO) : a morphological and anatomical ontology of flowering plants / Katica Ilic, ... [et al.] -- Anatomy for clinical terminology / Alan L. Rector -- The foundational model of anatomy ontology / Cornelius Rosse and José L. V. Mejino, Jr. -- Towards a disease ontology / Paul N. Schofield, Björn Rozell, Georgios V. Gkoutos -- Engineering and linking of anatomy ontologies -- Ontology alignment and merging / Patrick Lambrix, He Tan -- COBrA and COBrA-CT : ontology engineering tools / Stuart Aitken, Yin Chen -- XSPAN : a cross-species anatomy network / Albert Burger, Jonathan Bard -- Searching biomedical literature with anatomy ontologies / Thomas Wächter, ... [et al.] -- Anatomy ontologies and spatio-temporal atlases -- Anatomical ontologies : linking names to places in biology / Richard A. Baldock, Albert Burger -- Time in anatomy / Duncan Davidson -- The Edinburgh mouse atlas / Richard Baldock, Duncan Davidson -- The smart atlas : spatial and semantic strategies for multiscale integration of brain data / Maryann E. Martone, ... [et al.] -- Anatomy ontologies : modelling principles -- Modelling principles and methodologies : relations in anatomical ontologies / Fabian Neuhaus, Barry Smith -- Modeling principles and methodologies : spatial representation and reasoning / Thomas Bittner, ... [et al.] -- CARO : the common anatomy reference ontology / Melissa A. Haendel, ... [et al.]
  • 2008
    Swanson, Todd A.; Kim, Sandra I.; Kushen, Medina C.
    Status: Not Checked OutLane Catalog Record
  • 2013
    Decoteau, Claire Laurier.
    "In the years since the end of apartheid, South Africans have enjoyed a progressive constitution, considerable access to social services for the poor and sick, and a booming economy that has made their nation into one of the wealthiest on the continent. At the same time, South Africa experiences extremely unequal income distribution, and its citizens suffer the highest prevalence of HIV in the world. As Archbishop Desmond Tutu has noted, "AIDS is South Africa's new apartheid." In Ancestors and Antiretrovirals, Claire Laurier Decoteau backs up Tutu's assertion with powerful arguments about how this came to pass. Decoteau traces the historical shifts in health policy after apartheid and describes their effects, detailing, in particular, the changing relationship between biomedical and indigenous health care, both at the national and the local level. Decoteau tells this story from the perspective of those living with and dying from AIDS in Johannesburg's squatter camps. At the same time, she exposes the complex and often contradictory ways that the South African government has failed to balance the demands of neoliberal capital with the considerable health needs of its population." -- Publisher's description.
  • 2012 Springer Protocols
    Hofreiter, Michael; Shapiro, Beth Alison.
    Setting up an ancient DNA laboratory / Tara L. Fulton -- A phenol-chloroform protocol for extracting DNA from ancient samples / Ross Barnett and Greger Larson -- DNA extraction of ancient animal hard tissue samples via adsorption to silica particles / Nadin Rohland -- Case study : recovery of ancient nuclear DNA from toe pads of the extinct passenger pigeon / Tara L. Fulton, Stephen M. Wagner, and Beth Shapiro -- Extraction of DNA from paleofeces / Melanie Kuch and Hendrik Poinar -- DNA extraction from keratin and chitin / Paula F. Campos and Thomas M.P. Gilbert -- Case study : ancient sloth DNA recovered from hairs preserved in paleofeces / Andrew A. Clack, Ross D.E. MacPhee, and Hendrik N. Poinar -- Ancient DNA extraction from soils and sediments / James Haile -- DNA extraction from fossil eggshell / Charlotte L. Oskam and Michael Bunce -- Ancient DNA extraction from plants / Logan Kistler -- DNA extraction from formalin-fixed material / Paula F. Campos and Thomas M.P. Gilbert -- Case study : ancient DNA recovered from Pleistocene-age remains of a Florida armadillo / Brandon Letts and Beth Shapiro -- Nondestructive DNA extraction from museum specimens / Michael Hofreiter -- Case study : using a nondestructive DNA extraction method to generate mtDNA sequences from historical chimpanzee specimens / Elmira Mohandesan, Stefan Prost, and Michael Hofreiter -- PCR amplification, cloning, and sequencing of ancient DNA / Tara L. Fulton and Mathias Stiller -- Quantitative real-time PCR in aDNA research / Michael Bunce, Charlotte L. Oskam, and Morten E. Allentoft -- Multiplex PCR amplification of ancient DNA / Mathias Stiller and Tara L. Fulton -- Preparation of next-generation sequencing libraries from damaged DNA / Adrian W. Briggs and Patricia Heyn -- Generating barcoded libraries for multiplex high-throughput sequencing / Michael Knapp, Mathias Stiller, and Matthias Meyer -- Case study : targeted high-throughput sequencing of mitochondrial genomes from extinct cave bears via direct multiplex PCR sequencing (DMPS) / Mathias Stiller -- Target enrichment via DNA hybridization capture / Susanne Horn -- Case study : enrichment of ancient mitochondrial DNA by hybridization capture / Susanne Horn -- Analysis of high-throughput ancient DNA sequencing data / Martin Kircher -- Phylogenetic analysis of ancient DNA using BEAST / Simon Y.W. Ho.
  • Nutton, Vivian.
    1. Sources and scope -- 2. Patterns of disease -- 3. Before Hippocrates -- 4. Hippocrates, the Hippocratic Corpus and the defining of medicine -- 5. Hippocratic theories -- 6. Hippocratic practices -- 7. Religion and medicine in fifth- and fourth-century Greece -- 8. From Plato to Praxagoras -- 9. Alexandria, anatomy and experimentation -- 10. Hellenistic medicine -- 11. Rome and the transplantation of Greek medicine -- 12. The Consequences of empire: pharmacology, surgery and the Roman army -- 13. The Rise of Methodism -- 14. Humoral alternatives -- 15. The Life and career of Galen -- 16. Galenic medicine -- 17. All sorts and conditions of (mainly) men -- 18. Medicine and the religions of the Roman Empire -- 19. Medicine in the Later Roman Empire -- 20. Conclusion.
  • 2007
    Andreoli, Thomas E.; Benjamin, Ivor J.; Carpenter, Charles C. J.; Cecil, Russell L.; Griggs, Robert C.
    Status: Not Checked OutLane Catalog Record
  • 2016 ClinicalKey
    Benjamin, Ivor J.; Carpenter, Charles C. J.; Cecil, Russell L.; Fitz, J. Gregory; Griggs, Robert C.; Wing, Edward J.
    Introduction to molecular medicine -- Cardiovascular disease -- Pulmonary and critical care medicine -- Preoperative and postoperative care -- Renal disease -- Gastrointestinal disease -- Diseases of the liver and biliary system -- Hematologic disease -- Oncologic disease -- Endocrine disease and metabolic disease -- Women's health -- Men's health -- Diseases of bone and bone mineral metabolism -- Musculoskeletal and connective tissue disease -- Infectious disease -- Neurologic disease -- Geriatrics -- Palliative care -- Alcohol and substance abuse.
  • 2006
    James, William D.; Andrews, George Clinton; Berger, Timothy G.; Elston, Dirk M.
    Status: Not Checked OutLane Catalog Record
  • 2016 ClinicalKey
    James, William D.; Andrews, George Clinton; Berger, Timothy G.; Elston, Dirk M.
    1. Skin : basic structure and function -- 2. Cutaneous signs and diagnosis -- 3. Dermatoses resulting from physical factors -- 4. Pruritus and neurocutaneous dermatoses -- 5. Atopic dermatitis, eczema, and noninfectious immunodeficiency disorders -- 6. Contact dermatitis and drug eruptions -- Erythema and urticaria -- 7. Connective tissue diseases -- 8. Mucinoses -- 9. Seborrheic dermatitis, psoriasis, recalcitrant palmoplantar eruptions, pustular dermatitis, and erythroderma -- 11. Pityriasis rosea, pityriasis rubra pilaris, and other papulosquamous and hyperkeratotic diseases -- 12. Lichen planus and related conditions -- 13. Acne -- 14. Bacterial infections -- 15. Diseases resulting from fungi and yeasts -- 16. Mycobacterial diseases -- 17. Hansen's disease -- 18. Syphilis, yaws, bejel, and pinta -- 19. Viral diseases -- 20. Parasitic infestations, stings, and bites -- 21. Chronic blistering dermatoses -- 22. Nutritional diseases -- 23. Diseases of subcutaneous fat -- 24. Endocrine diseases -- 25. Abnormalities of dermal fibrous and elastic tissue -- 26. Errors in metabolism -- 27. Genodermatoses and congenital anomalies -- 28. Dermal and subcutaneous tumors -- 29. Epidermal nevi, neoplasms, and cysts -- 30. Melanocytic nevi and neoplasms -- 31. Macrophage/monocyte disorders -- 32. Cutaneous lymphoid hyperplasia, cutaneous t-cell lymphoma, other malignant lymphomas, and allied diseases -- 33. Diseases of the skin appendages -- 34. Disorders of the mucous membranes -- 35. Cutaneous vascular diseases -- 36. Disturbances of pigmentation -- 37. Dermatologic surgery -- 38. Cutaneous laser surgery -- 39. Cosmetic dermatology.
  • 2011 Springer Protocols
    Saatcioglu, Fahri.
    Section I : Reviews -- 1. Molecular mechanisms of androgen action : A historical perspective / Albert O. Brinkmann -- 2. Androgen action during prostate carcinogenesis / Diping Wang and Donald J. Tindall -- Section II : Analysis of androgens -- 3. Androgen quantitation in prostate cancer tissue using liquid chromatography tandem mass spectrometry / Mark Titus and Kenneth B. Tomer -- 4. Ligand competition binding assay for the androgen receptor / Clémentine Féau [and others] -- Section III : Androgen receptor biology -- 5. Analysis of androgen receptor activity by reporter gene assays / Harri Makkonen [and others] -- 6. Identification and characterization of androgen response elements / Reinhilde de Bruyn, Rita Bollen, and Frank Claessens -- 7. In vitro and in vivo silencing of the androgen receptor / Helen Cheng, Eric Leblanc, and Paul S. Rennie -- 8. Analysis of interdomain interactions of the androgen receptor / Elizabeth M. Wilson -- 9. Methods to study dynamic interaction of androgen receptor with chromatin in living cells / Hatice Zeynep Kirli and Fahri Saatcioglu -- 10. FRET analysis of androgen receptor structure and biochemistry In living cells / Fred Schaufele -- Section IV : Analysis of androgen receptor modifications and interactions -- 11. Analysis of nuclear receptor acetylation / Chenguang Wang [and others] -- 12. Analysis of androgen receptor SUMOylation / Miia M. Rytinki [and others] -- 13. Analysis of ligand-specific co-repressor binding to the androgen receptor / Claudia Gerlach, Daniela Roell, and Aria Baniahmad --14. Detection of ligand-selective interactions of the human androgen receptor by SELDI-MS-TOF / Thomas Linke, Martin Scholten, and Aria Baniahmad -- Section V : Recent advances in studying androgen receptor signaling --15. Global identification of androgen response elements / Charles E. Massie and Ian G. Mills --16. Tissue-specific knockout of androgen receptor in mice / Tzu-hua Lin, Shuyuan Yeh, and Chawnshang Chang -- 17. Methodology to investigate androgen-sensitive and castration resistant human prostate cancer xenografts in preclinical setting / Holly M. Nguyen and Eva Corey -- 18. Automated microscopy and image analysis for androgen receptor function / Sean M. Hartig [and others] -- Section VI : Cross-talk of androgen and other signalling pathways -- 19. Androgen regulation of ETS gene fusion transcripts in prostate cancer / Delila Basi and Jan Trapman -- 20. Regulation of apoptosis by androgens in prostate cancer cells / Yke Jildouw Arnoldussen, Ling Wang, and Fahri Saatcioglu -- 21. Analysis of androgen receptor rapid actions in cellular signaling pathways : receptor/src association / Antimo Migliaccio, Gabriella Castoria, and Ferdinando Auricchio -- 22. Analysis of androgen-induced increase in lipid accumulation in prostate cancer cells / Jorgen Sikkeland, Torstein Lindstad, and Fahri Saatcioglu.
  • 2009 Springer
    Mohler, James; Tindall, Donald.
    Androgen action and modulation of prostate and prostate cancer growth : an historical perspective / Shutsung Liao ... [et al.] -- Clinical progression to castration-recurrent prostate cancer / Mark Pomerantz and Philip Kantoff -- Differential roles of androgen receptor in prostate development and cancer progression / Shuyuan Yeh ... [et al.] -- Imaging androgen receptor function in vivo / Michael Carey and Lily Wu -- Increased expression of genes converting adrenal androgens to testosterone in castration-recurrent prostate cancer / Steven P. Balk -- Androgen-metabolic genes in prostate cancer predisposition and progression / Juergen K.V. Reichardt and Ann W. Hsing -- Effect of steroid 5[alpha]-reductase inhibitors on markers of tumor regression and proliferation in prostate cancer / Lynn N. Thomas and Roger S. Rittmaster -- 5[alpha]-reductase isozymes in castration-recurrent prostate cancer / Mark A. Titus and James L. Mohler -- Improving intermittent androgen-deprivation therapy : OFF cycle and the role of steroid 5[alpha]-reductase inhibitors / Shubham Gupta, Daniel Shevrin, and Zhou Wang -- Insights from AR gene mutations / Grant Buchanan ... [et al.] -- Functional motifs of the androgen receptor / Elizabeth M. Wilson -- The role of the androgen receptor polyglutamine tract in prostate cancer : in mice and men / Diane M. Robbins -- The androgen receptor coactivator-binding interface / Eva Estébanez-Perpiñá and Robert J. Fletterick -- Co-regulators and the regulation of androgen receptor action in prostate cancer / Irina U. Agoulnik and Nancy L. Weigel -- Androgen receptor coregulators and their role in prostate cancer / Latif A. Wafa, Robert Snoek, and Paul S. Rennie -- Interaction of the androgen receptor ligand-binding domain with the n-terminal domain and with coactivators / Jan Trapman -- Multitasking and interplay between the androgen receptor domains / F.Claessens, T. Tanner, and A. Haelens -- Chromatin remodeling and androgen receptor-mediated transcription / Li Jia ... [et al.] -- Ligand-independent androgen receptor activity / Scott M. Dehm and Donald J. Tindall -- Role of IL-6 in regulating the androgen receptor / Zoran Culig and Alfred Hobisch -- The role of cyclic AMP in regulating the androgen receptor / Marianne D. Sadar -- Cellular and molecular signatures of androgen ablation of prostate cancer / Clifford G. Tepper and Hsing-Jien Kung -- Tissue levels of androgens in castration-recurrent prostate cancer / James L. Mohler and Mark A. Titus -- Unique effects of wnt signaling on prostate cancer cells : modulation of the androgen signaling pathway by interactions of the androgen receptor gene and protein with key components of the canonical wnt signaling pathway / Matthew J. Tanner ... [et al.] -- The role of foxa proteins in the regulation of androgen receptor activity / David J. DeGraff ... [et al.] -- Androgen receptor as a licensing factor for DNA replication / Donald J. Vander Griend and John T. Isaacs -- Androgen-regulated genes in the prostate / Nigel Clegg and Peter S. Nelson -- Mapping the androgen receptor cistrome / Qianben Wang and Myles Brown -- Differential regulation of clusterin isoforms by the androgen receptor Tanya K. Day, Colleen C. Nelson, and Martin E. Gleave -- Androgen regulation of prostate cancer gene fusions / Rou Wang, Scott A. Tomlins, and Arul M. Chinnaiyan -- Androgens and the lipogenic switch in prostate cancer / Johannes V. Swinnen ... [et al.] -- Molecular biology of novel targets identified through study of castration-recurrent prostate cancer / Philip A. Watson and Charles L. Sawyers -- Selenium and androgen receptor in prostate cancer / Nagalakshmi Nadiminty and Allen C. Gao.
  • 2013 Springer
    Hellstrom, Wayne J. G.
    1. The Institute of Medicine White Paper on Testosterone: Current Perspective / Craig F. Donatucci -- 2. The Laboratory Diagnosis of Testosterone Deficiency / Akanksha Mehta and Darius A. Paduch -- 3. The Clinical Diagnosis of Androgen Deficiency / Gregory C. Mitchell, Ege Can Serefoglu, and Wayne J.G. Hellstrom -- 4. The Use of Patient Reported Outcome Questionnaires in the Diagnosis of Androgen Deficiency / Gregory J. Lowe, George C. Bailey, and Tracey L. Krupski -- 5. Testosterone and Its Association with Metabolic and Cardiovascular Disease / Giovanni Corona, Giulia Rastrelli, and Mario Maggi -- 6. The Role of Androgens in Prostate Cancer / Frances Alba, Claudio A. Romero, and Run Wang -- 7. Androgen Deficiency in the Adolescent Male / Erin R. McNamara and Sherry S. Ross -- 8. Effects of Androgen Deficiency and Replacement on Male Fertility / Andrew C. Kramer -- 9. HIV and Testosterone in Men / Gina Cambareri, Jane Ashby, David Goldmeier, and Hossein Sadeghi-Nejad -- 10. Treatment Options for Testosterone Replacement Therapy / Mohit Khera -- 11. Alternate Therapies for Testosterone Replacement / Ege Can Serefoglu, Ahmet Gokce, Wayne J.G. Hellstrom, and André T. Guay.
  • 2006 Springer
    Azziz, Ricardo; Dewailly, Didier; Nestler, John E.
    A brief history of androgen excess / Ricardo Azziz -- Ovarian and adrenal androgen biosynthesis and metabolism / Walter L. Miller, David H. Geller, and Mitchell Rosen -- Androgens throughout the life of women / C. Richard Parker, Jr. -- Physiological effects of androgens in women / T. Keta Hodgson and Glenn D. Braunstein -- Androgen measurements: methods, interpretation, and limitations / Frank Z. Stanczyk -- Androgen-secreting adrenal and ovarian neoplasms / Michel Pugeat ... [et al.] -- Cushing's syndrome, acromegaly, and androgen excess / Anne-Céline Reyss and Didier Dewailly -- The nonclassic adrenal hyperplasias / Didier Dewailly and Ricardo Azziz -- Pregnancy-related androgen excess / Howard D. McClamrock -- Drug-induced hyperandrogenism / Barbara Neraud and Didier Dewailly -- Severe insulin-resistant hyperandrogenic syndromes / David E. Moller, Antonio Vidal-Puig, and Ricardo Azziz -- Idiopathic hirutism / Enrico Carmina -- Definition and epidemiology of the polycystic ovary syndrome / Ricardo Azziz -- Clinical features of the polycystic ovary syndrome / Walter Futterweit, Evanthia Diamanti-Kandarakis, and Ricardo Azziz -- Biochemical features of the polycystic ovary syndrome / Adam H. Balen -- Ovarian histology, morphology, and ultrasonography in the polycystic ovary syndrome / Sophie Jonard ... [et al.] -- Hypothalamic-pituitary-gonadtrophic dysfunction in the polycystic ovary syndrome / R. Jeffrey Chang and Rinku V. Mehta -- Ovarian steroidogenic abnormalities in the polycystic ovary syndrome / Denis A. Magoffin -- Hypothalamic-pituitary-adrenal dysfunction in the polycystic ovary syndrome / Bulent O. Yildiz, Enrico Carmina, and Ricardo Azziz -- The genetic basis of the polycystic ovary syndrome / Mark O. Goodarzi -- Pediatric hyperandrogenism and the polycystic ovary syndrome in adolescence / Kathleen M. Hoeger -- Environmental factors in the polycystic ovary syndrome / Marie-France Hivert and Jean-Patrice Baillargeon -- Animal models and fetal programming of the polycystic ovary syndrome / David H. Abbott ... [et al.] -- Insulin resistance and hyperinsulinism in the polycystic ovary syndrome / Paulina A. Essah and John E. Nestler -- The endocrine impact of obesity and body habitus in the polycystic ovary syndrome / Renato Pasquali and Alessandra Gambineri -- Molecular mechanisms of insulin resistance in the polycystic ovary syndrome / Theodore P. Ciaraldi -- Menstrual dysfunction and endometrial neoplasia in the polycystic ovary syndrome / Abdulkadir Wagley and Paul Hardiman -- Beta-cell dysfunction, glucose intolerance, and diabetes in the polycystic ovary syndrome / David A. Ehrmann -- Hypertension and cardiovascular and lipoprotein abnormalities in the polycystic ovary syndrome / Francesco Orio and Stefano Palomba -- Reproductive and obstetrical consequences of the polycystic ovary syndrome / Mary C. Johnson and Richard S. Legro -- Psychosocial and quality-of-life consequences of androgen excess and the polycystic ovary syndrome / Onno E. Janssen, Susanne Hahn, and Sigrid Elsenbruch -- Overview of long-term morbidity and economic cost of the polycystic ovary syndrome / Ricardo Azziz -- Clinical and hormonal evaluation of androgen excess / Ricardo Azziz -- Ovarian suppression and treatment of hirsutism / Paolo Moghetti -- Polycystic ovary syndrome and ovulation induction / Bulent O. Yildiz and Ricardo Azziz -- In vitro fertilization for the polycystic ovary syndrome / Hanadi Ba-Akdah ... [et al.] -- Surgical management of the polycystic ovary syndrome / Adam H. Balen -- Use of insulin sensitizers in the polycystic ovary syndrome / Kai I. Cheang and John E. Nestler -- Weight reduction and lifestyle modification in the treatment of androgen excess / Manny Noakes ... [et al.].
    Also available: Print – 2006
  • 2013 Springer
    Wang, Zhou.
    Recent studies demonstrated a key role of the androgen receptor in the development of castration-recurrent or -resistant prostate cancer (CRPC), which is deadly and in urgent need of more effective therapies. Understanding the functions of androgen-responsive genes and their regulation and deregulation in prostate cancer progression may lead to new approaches to prevent and treat prostate cancer patients. This book provides an up-to-date review of the overall androgen-responsive gene expression program and the regulation, function, and clinical relevance of both protein coding and non-coding androgen-responsive genes. Experts in the field of androgen action and prostate cancer research discussed the importance of DNA elements, chromatin structure, cellular signaling, and cell-cell interactions in the regulation of androgen-responsive genes in the context of prostate cancer progression, including the development of CRPC. This book is intended for individuals interested in cancer endocrinology and medical and healthcare professionals involved in prostate cancer research.
  • 2010 Springer
    Behre, Hermann M.; Nieschlag, Eberhard; Nieschlag, Susan.
    1. Scope and goals of andrology / Eberhard Nieschlag -- 2. Physiology of testicular function / Gerhard F. Weinbauer ... [et al.] -- 3. Physiology of sperm maturation and fertilization / Trevor G. Cooper and Ching-Hei Yeung -- 4. Classification of andrological disorders / Frank Tüttelmann and Eberhard Nieschlag -- 5. Anamnesis and physical examination / Eberhard Nieschlag and Hermann M. Behre -- 6. Imaging diagnostics / Hermann M. Behre and Michael Zitzmann -- 7. Endocrine laboratory diagnosis / Manuela Simoni and Eberhard Nieschlag -- 8. Cytogenetic and molecular genetic investigations / Manuela Simoni and Peter Wieacker -- 9. Semen analysis / Trevor G. Cooper -- 10. Sperm quality and function tests / Ching-Hei Yeung and Trevor G. Cooper -- 11. Testicular biopsy and histology / Martin Bergmann and Sabine Kliesch -- 12. Diseases of the hypothalamus and the pituitary gland / Hermann M. Behre ... [et al.] -- 13. Disorders at the testicular level / Eberhard Nieschlag ... [et al.] -- 14. The aging male and late-onset hypogonadism / Claus Rolf, Michael Zitzmann, and Eberhard Nieschlag -- 15. Diseases of the seminal ducts / Hermann M. Behre ... [et al.] -- 16. Disorders of erection, cohabitation, and ejaculation / Hermann van Ahlen and Sabine Kliesch -- 17. Disorders of androgen target organs / Peter F. Wieacker, Hermann M. Behre, and Eberhard Nieschlag -- 18. Testicular dysfunction in systemic diseases / Gideon A. Sartorius and David J. Handelsman -- 19. Environmental influences on male reproductive health / Martin H. Brinkworth and David J. Handelsman -- 20. Gynecology relevant to andrology / Ulrich A. Knuth -- 21. Testosterone therapy / Eberhard Nieschlag and Hermann M. Behre -- 22. Empirical therapies for idiopathic male infertility / Eberhard Nieschlag and Axel Kamischke -- 23. Assisted reproduction / Christian De Geyter, Maria De Geyter, and Hermann M. Behre -- 24. Cryopreservation of human spermatozoa / Sabine Kliesch ... [et al.] -- 25. Psychology of fertility disorders / Regina Oberpenning, Fritz A. Muthny, and Frank Oberpenning -- 26. Sexual medicine and andrology / Klaus M. Beier -- 27. Male contribution to contraception / Eberhard Nieschlag -- 28. Vasectomy and refertilization / Udo H. Engelmann and Oliver Gralla -- 29. Approaches to hormonal male contraception / Eberhard Nieschlag and Hermann M. Behre -- 30. Pharmacological approaches to male contraception / Trevor G. Cooper and Ching-Hei Yeung -- 31. Ethical aspects of reproductive medicine / Klaus Demmer.
  • 2006 Springer
    Comhaire, F. H.; Hargreave, Timothy B.; Schill, W.-B.
    Also available: Print – 2006
  • 2007 Springer
    Balducci, Lodovico; Bennett, John M.; Ershler, William B.
  • 2010 ClinicalKey
    Hall, Brian A.; Chantigian, Robert C.
    Anesthesia equipment and physics -- Respiratory physiology and critical care medicine -- Pharmacology and pharmacokinetics of intravenous drugs -- Pharmacology and pharmacokinetics of volatile anesthetics -- Blood products, transfusion, and fluid therapy -- General anesthesia -- Pediatric physiology and anesthesia -- Obstetric physiology and anesthesia -- Neurologic physiology and anesthesia -- Anatomy, regional anesthesia, and pain management -- Cardiovascular physiology and anesthesia.
  • 2011 Springer
    Park, Kyung W.; Subramaniam, Balachundhar; Subramaniam, Kathirvel.
    Applied anatomy of the aorta -- Acute aortic syndrome -- Preoperative cardiac evaluation before aortic surgery -- Role of echocardiography in aortic surgery -- Operative techniques in surgery of the proximal thoracic aorta and aortic arch -- Anesthesia for surgery of the ascending aorta and aortic arch -- Deep hypothermic circulatory arrest -- Cerebral monitoring during aortic surgery -- Understanding open repair of the descending thoracic and thoracoabdominal aorta -- Anesthesia for descending aortic surgery -- Spinal cord protection strategies -- Understanding endovascular aortic surgery: Endovascular repair of aortic aneurysmal disease -- Anesthesia for endovascular aortic surgery -- Anesthesia for open abdominal aortic aneurysm repair -- Renal protection strategies -- Comprehansive management of patients with traumatic aortic injury -- Anesthesia for adult congenital aortic surgery -- Atherosclerosis of the aorta and prevention of neurological dysfunction after cardiac surgery -- Postoperative care after aortic surgery.
  • 2013 Wiley
    Ginosar, Yehuda.
    Section 1: Basic Principles. Intrauterine Growth and Development / Timothy J M Moss, Cheryl A Albuquerque, Richard Harding -- Maternal Physiological Adaptations to Pregnancy / Julie Phillips, Melissa Covington, George Osol -- Placental Respiratory Gas Exchange / Lowell Davis -- The Fetal Circulation / Loren P Thompson, Kazumasa Hashimoto -- Fetal Responses to Hypoxia / Tania L Kasdaglis, Ahmet A Baschat -- Pharmacokinetics in Pregnancy / Janine R Hutson, Chagit Klieger, Gideon Koren -- The First Few Breaths: Normal Transition from Intra- to Extra-Uterine Life / Smadar Eventov-Friedman, Benjamin Bar-Oz -- Section 2: Endpoint Variables: Assessments of Fetal Wellbeing and Neonatal Outcome. Validity of Endpoint Measurement / Pamela J Angle, Stephen Halpern, Marcos Silva Restrepo, Alexander J Kiss -- Imaging of the Fetus and the Uteroplacental Blood Supply: Ultrasound / Kypros Nicolaides -- Imaging of the Fetus and the Uteroplacental Blood Supply: MRI / Caroline Wright, Philip Baker -- Fetal Heart Rate Monitoring / Alison M Premo, Sarah J Kilpatrick -- Fetal Acid-Base Monitoring / Lennart Nordstrom -- Fetal Pulse Oximetry / Paul B Colditz, Christine East -- Neonatal Assessment and Prediction of Neonatal Outcome / Vadivelam Murthy, Anne Greenough -- Section 3: Interventions: Anesthesia, Analgesia, and their Effects on the Fetus. Environmental Exposure to Anesthetic Agents / Asher Ornoy -- Anesthesia and Analgesia for Assisted Reproduction Techniques and other Procedures during the First Trimester / Arvind Palanisamy, Lawrence C Tsen -- The Effect of Anesthetic Drugs on the Developing Fetus: Considerations in Non-Obstetric Surgery / Richard S Gist, Yaakov Beilin -- Substance Abuse and Pregnancy / Donald H Penning, Allison J Lee -- Intrauterine Fetal Procedures for Congenital Anomalies / Amar Nijagal, Hanmin Lee, Mark Rosen -- The EXIT procedure / Sheldon M Stohl, Hindi E Stohl, Ari Y Weintraub, Kha M Tran -- Mechanisms and Consequences of Anesthetic-Induced Neuroapoptosis in the Developing Brain / Zhaowei Zhou, Adam P Januszewski, Mervyn Maze, Daqing Ma -- Relevance to Clinical Anesthesia of Anesthetic-Induced Neurotoxicity in Developing Animals / Catherine E Creeley, Mervyn Maze, John W Olney -- External Cephalic Version / Carolyn F Weiniger, Yossef Ezra -- Effects on the Fetus of General Versus Regional Anesthesia / Sharon Orbach-Zinger, Yehuda Ginosar -- Anesthesia for Cesarean Delivery: Effects on the Fetus of Maternal Blood Pressure Control / Warwick D Ngan Kee -- Effects on the Fetus of Maternal Oxygen Administration / Neeti Sadana, Scott Segal -- Effects on the Fetus of Maternal Position During Cesarean Delivery / Robin Russell -- Effects on the Fetus of Systemic vs. neuraxial analgesia / Stephen H Halpern, Marcos Silva Restrepo -- The Effects on the Fetus of Early Versus Late Regional Analgesia / Cynthia A Wong -- Regional Analgesia, Maternal Fever, and its Effect on the Fetus and Neonate / Tabitha A Tanqueray, Philip J Steer, Steve M Yentis -- Effects on the Fetus of Major Maternal Anesthetic Complications / Felicity Plaat, Ruth Bedson -- Section 4: Confounding Variables: The Compromised Fetus, the Compromised Mother. Multiple Pregnancy / Yehuda Habaz, Jon Barrett, Eric S Shinwell -- Preeclampsia: The Compromised Fetus, the Compromised Mother / Todd R Lovgren, Henry L Galan -- Fetal Distress / Robert A Dyer, Leann K Schoeman -- Section 5: Trauma and Resuscitation. Maternal Trauma / Yuval Meroz, Uriel Elchalal, Avraham I Rivkind -- Maternal Resuscitation and Perimortem Cesarean Delivery / Sharon Einav, Sorina Grisaru-Granovsky, Joseph Varon -- Intrauterine Fetal Resuscitation / Stephen Michael Kinsella, Andrew Shennan -- Neonatal Resuscitation and Immediate Neonatal Emergencies / Ritu Chitkara, Anand K Rajani, Louis P Halamek -- Section 6: Medicine, Ethics, and the Law. Fetal Beneficence and Maternal Autonomy: Ethics and the Law / William J Sullivan, Joanne Douglas -- Maternal-Fetal Research in Pregnancy / Frank A Chervenak, Laurence B McCullough.