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  • 2007 CRCnetBASE
    edited by Eleazar Shafrir.
    Pigs in diabetes research with special focus on type 2 diabetes / M.O. Larsen, B. Rolin -- Psammomys obesus : nutritionally induced insulin resistance, diabetes and beta cell loss / E. Ziv, R. Kalman, and E. Shafrir -- The spontaneously diabetic Torii (SDT) rat with human resembling retinopathy lesions / M. Shinohara, T. Masuyama, A. Kakehashi -- The Cohen diabetic rat / S. Weksler-Zangen, E. Orlinsky, D.H. Zangen -- Kk and KKay mice : models of type 2 diabetes and obesity / S. Taketomi -- Animal models to study obesity and type II diabetes induced by diet / Tamer Coskun ... [et al.]. Rat models of type 1 diabetes : genetics, environment, and autoimmunity / J.P. Mordes ... [et al.] -- The NOD mouse and its related strains / H. Taniguchi, S. Makino, H. Ikegami -- Obesity/diabetes in mice with mutations in the leptin or leptin receptor genes / S. Chua Jr., L. Herberg, E.H. Leiter -- The Zucker diabetic fatty (ZDF) rat--lessons from leptin receptor defect diabetic model / R.G. Peterson -- The Goto-Kakizaki diabetic rat evolved by selective breeding / C.J. Ostenson -- The new zealand obese mouse : a polygenic model of obesity, glucose intolerance and the metabolic syndrome / B.C. Fam, S. Andrikopoulos -- The JCR:LA-cp rat : a model of the metabolic syndrome exhibiting micro-and macro-vascular disease / J.C. Russel, S.E. Kelly, S.D. Proctor -- The SHROB (Koletsky) rat as a model for metabolic syndrome / R.J. Koletzky, R.A. Velliquette, P. Ernsberger -- OLETF rats : a model for the metabolic syndrome and diabetic nephropathy in humans / K. Kawano -- Neonatally streptrozotocin-induced (n-STZ) diabetic rats, a family of type 2 diabetes models / B. Portha ... [et al.] -- The Rhesus monkey (Macaca mulatta) manifests all features of human type 2 diabetes / B. Hansen and Xenia T. Tigno --
  • 2011 Springer Protocols
    edited by Mary C. Olmstead.
    Intracranial self-stimulation / Styliani Vlachou and Athina Markou -- Stimulant self-administration / Leigh V. Panlilio -- Opiate self-administration / Francesco Leri -- Nicotine self-administration / Robert E. Sorge and Paul B.S. Clarke -- Alcohol self-administration / Friedbert Weiss -- Place conditioning / Christopher L. Cunningham, Peter A. Groblewski, and Charlene M. Voorhees -- Sensitization / Jessica A. Loweth and Paul Vezina -- Animal models of eating disorders / Stephanie D. Hancock and Mary C. Olmstead -- Acquisition of drug self-administration / Marilyn E. Carroll and Richard A. Meisch -- Escalation of drug use / Serge H. Ahmed -- Environmental modulation of drug taking / Aldo Badiani ... [et al.] -- Craving / Jeffrey W. Grimm -- Habit formation and compulsion / David Belin ... [et al.] -- Impulsivity / Andrea Bari, Trevor W. Robbins, and Jeffrey W. Dalley -- Binge drug taking / Herbert E. Covington, III and Klaus A. Miczek -- Withdrawal / Alasdair M. Barr, Heidi N. Boyda, and Ric M. Procyshyn -- Relapse / Suzanne Erb and Franca Placenza.
  • 2013 Springer Protocols
    edited by Nicole M. Avena.
    Introduction : binge eating, bulimia nervosa, and hedonic overeating / Sarah Shafer Berger and Marian Tanofsky-Kraff -- Binge-prone versus binge-resistant rats and their concomitant behavioral profiles / Mary M. Boggiano -- Binge eating in female rats induced by yo-yo dieting and stress / Carlo Cifani, Maria Vittoria Micioni Di Bonaventura, Roberto Ciccocioppo, and Maurizio Massi -- Binge-type eating induced by limited access to optional foods / Rebecca L.W. Corwin and Francis H.E. Wojnicki -- Assessment of stress-independent binge-like eating behavior in mice / Traci A. Czyzyk, Jesline Alexander-Chacko, Joelle Dill, Dana K. Sindelar, and Michael A. Statnick -- Predicting and classifying rats prone to overeating fat / Irene Morganstern, Jessica R. Barson, and Sarah F. Leibowitz -- Modeling binge eating in nonhuman primates / Richard W. Foltin -- Psychosocial stress and diet history promote emotional feeding in female rhesus monkeys / Vasiliki Michopoulos, Carla Moore, and Mark E. Wilson -- Stressful experiences in early life and subsequent food intake / Jeong Won Jahng -- Sham feeding in rats translates into modified sham feeding in women with bulimia nervosa and purging / Diane A. Klein and Gerard P. Smith -- Animal models of binge eating palatable foods : emergence of addiction-like behaviors and brain changes in the rat / Miriam E. Bocarsly and Nicole M. Avena -- Deep brain stimulation for the treatment of binge eating : mechanisms and preclinical models / Casey H. Halpern, Mark Attiah, and Tracy L. Bale -- Saccharin preference in rats : relation to impulsivity and drug abuse / Marilyn E. Carroll, Nathan A. Holtz, and Natalie E. Zlebnik -- Food seeking in spite of harmful consequences / Rossella Ventura, Emanuele Claudio Latagliata, Enrico Patrono, Matteo Di Segni, and Stefano Puglisi-Allegra -- Introduction : anorexia and undereating / Guido K.W. Frank -- Food restriction and reward in rats / Kenneth D. Carr and Soledad Cabeza de Vaca -- Activity-based anorexia in the rat / Nicole C. Barbarich-Marsteller -- Food-anticipatory activity : rat models and underlying mechanisms / Myrte Merkestein, Linda A.W. Verhagen, and Roger A.H. Adan -- Anorexia and drugs of abuse abnormally suppress appetite, the result of a shared molecular signal foul-up / Laetitia Laurent, Alexandra Jean, Christine Manrique, Mohamed Najimi, Fatiha Chigr, and Valérie Compan -- Anorectic phenotype of the anx/anx mouse is related to hypothalamic dysfunction / Ida A.K. Nilsson, Charlotte Lindfors, Tomas Hökfelt, Martin Schalling, and Jeanette E. Johansen -- Functional magnetic resonance imaging in awake rats : studies relevant to addiction and the reward circuitry / Marcelo Febo.
  • 2009 Springer Protocols
    Baraban, Scott C.
    The nematode, Caenorhabditis elegans, as an emerging model for investigating epilepsy / Cody J. Locke, Kim A. Caldwell, and Guy A. Caldwell -- The genetics and molecular biology of seizure susceptibility in drosophila / Juan Song and Mark A. Tanouye -- The albino Xenopus laevis tadpole as a novel model of developmental seizures / D. Sesath Hewapathirane and Kurt Haas -- Zebrafish as a simple vertebrate organism for epilepsy research / Scott C. Baraban -- Modeling tuberous sclerosis complex: brain development and hyperexcitability / Devin C. Ess -- BK potassium channel mutations affecting neuronal function and epilepsy / David Petrik, Qing H. Chen, and Robert Brenner -- Mouse models of benign familial neonatal convulsions (BFNC): mutations in KCNQ (Kv7)genes / Nanda A. Singh ... [et al.] -- Interneuron loss as a cause of seizures: lessons from interneuron-deficient mice / Dorothy Jones-Davis, Maria-Elisa Calcagnotto, and Joy Y. Sebe -- Imaging seizure propagation in vitro / Andrew J. Trevelyan and Rafael Yuste -- Complexity untangled: large-scale realistic computational models in epilepsy / Robert J. Morgan and Ivan Soltesz -- Organotypic hippocampal slice cultures as a model of limbic epileptogenesis / Suzanne B. Bausch -- Seizure analysis and detection in vivo / Javier Echauz, Stephen Wong, and Brian Litt -- Viral vector gene therapy for epilepsy / Stacey B. Foti, Shelley J. Russek, Amy R. Brooks-Kayal, and Thomas J. McCown -- Neural stem cells in experimental mesial temporal lobe epilepsy / Michelle M. Kron and Jack M. Parent.
  • 2009 Springer
    Jennifer L. Bizon, Alisa G. Woods, editors.
    Normal and pathological aging: from animals to humans / Nicole C. Berchtold and Carl W. Cotman -- Nonhuman primate models of cognitive aging / Agnès Lacreuse and James G. Herndon -- Age-related effects on prefrontal cortical systems: translating between rodents, nonhuman primates, and humans / Mark G. Baxter -- Comparison of different cognitive rat models of human aging / Candi LaSarge and Michelle Nicolle -- Mouse models of cognitive aging: behavioral tasks and neural substrates / Michael E. Calhoun -- Impact of Aβ and Tau on cognition in mouse models of Alzheimer's disease / Maya A. Koike ... [et al.] -- Hormonal influences of brain aging and age-related cognitive decline / Danielle K. Lewis and Farida Sohrabji -- Timing deficits in aging and neuropathology / Fuat Balci ... [et al.].
  • v.1-2=, 2011 Springer Protocols
    v.2 (2011) Springer Protocols
    edited by Emma L. Lane, Stephen B. Dunnett.
    V.1 : Why cannot a rodent be more like a man? A clinical perspective / Anne E. Rosser -- Zebrafish as a vertebrate model organism for studying movement disorders / Maria Sundvik and Pertti Panula -- Methodological strategies to evaluate functional effectors related to Parkinson's disease through application of Caenorhabditis elegans Models/ Kim A. Caldwell and Guy A. Caldwell -- Effects of alpha-synuclein expression on behavioral activity in Drosophila : a simple model of Parkinson's disease / Robert G. Pendleton [and others] -- Neurological evaluation of movement disorders in mice / Simon P. Brooks -- Rodent skilled reaching for modeling pathological conditions of the human motor system / Jenni M. Karl and Ian Q. Whishaw -- High-throughput mouse phenotyping / Sabine M. Holter and Lisa Glasl -- MRI of neurological damage in rats and mice / Mathias Hoehn -- Quantification of brain function and neurotransmission system in vivo by positron emission tomography : a review of technical aspects and practical considerations in preclinical research / Nadja Van Camp, Yann Bramoulle, and Philippe Hantraye -- Optical approaches to studying the basal ganglia / Joshua L. Plotkin [and others] -- Electrophysiological analysis of movement disorders in mice / Shilpa P. Rao [and others] -- Genetic models of Parkinson's disease / Ralf Kuhn, Daniela Vogt-Weisenhorn, and Wolfgang Wurst -- 6-OHDA lesion models of Parkinson's disease in the rat / Eduardo M. Torres and Stephen B. Dunnett -- 6-OHDA toxin model in mouse / Gaynor A. Smith and Andreas Heuer -- Rotation in the 6-OHDA-lesioned rat / Stephen B. Dunnett and Eduardo M. Torres -- Of rats and patients : some thoughts about why rats turn in circles and Parkinson's disease patients cannot move normally / Gordon W. Arbuthnott -- Comparing behavioral assessment of sensorimotor function in rat and mouse models of Parkinson's disease and stroke / Sheila M. Fleming and Timothy Schallert -- Rodent models of l-DOPA-induced dyskinesia / Hanna S. Lindgren and Emma L. Lane -- Using the MPTP mouse model to understand neuroplasticity : a new therapeutic target for Parkinson's disease / Giselle M. Petzinger [and others] -- MPTP-treated primate, with specific reference to the use of the common marmoset (Callithrix jacchus) / Michael J. Jackson and Peter Jenner -- Behavioral assessment in the african green monkey after MPTP administration / D. Eugene Redmond Jr. V. 2: Part I Generic methods of assessment -- Why cannot a rodent be more like a man? a clinical perspective / Anne E. Rosser -- Zebrafish as a vertebrate model organism for studying movement disorders / Maria Sundvik and Pertti Panula -- Methodological strategies to evaluate functional effectors related to parkinson's disease through application of caenorhabditis elegans models / Kim A. Caldwell and Guy A. Caldwell -- Effects of alpha-synuclein expression on behavioral activity in drosophila : a simple model of parkinson's disease / Robert G. Pendleton [and others] -- Neurological evaluation of movement disorders in mice / Simon P. Brooks -- Rodent skilled reaching for modeling pathological conditions of the human motor system / Jenni M. Karl and Ian Q. Whishaw -- High-throughput mouse phenotyping / Sabine M. Holter and Lisa Glasl -- MRI of neurological damage in rats and mice / Mathias Hoehn -- Quantification of brain function and neurotransmission system in vivo by positron emission tomography : a review of technical aspects and practical considerations in preclinical research / Nadja Van Coup, Yann Bramoulle, and Philippe Hantraye -- Optical approaches to studying the basal ganglia / Joshua L. Plotkin [and others] -- Electrophysiological analysis of movement disorders in mice / Shilpa P. Rao [and others] -- Part II Dopamine systems -- Genetic models of parkinson's disease / Ralf Kuhn, Daniela Vogt-Weisenborn, and Wolfgang Wurst -- 6-OHDA lesion models of parkinson's disease in the rat / Eduardo M. Torres and Stephen B. Dunnett -- 6-OHDA toxin model in mouse / Gaynor A. Smith and Andreas Heuer -- Rotation in the 6-OHDA-lesioned rat / Stephen B. Dunnett and Eduardo M. Torres -- Of rats and patients : some thoughts about why rats turn in circles and parkinson's disease patients cannot move normally / Gordon W. Arbuthnott -- Comparing behavioral assessment of sensorimotor function in rat and mouse models of parkinson's disease and stroke / Sheila M. Fleming and Timothy Schallert -- Rodent models of 1-DOPA-induced dyskinesia / Hanna S. Lindgren and Emma L. Lane -- Using the MPTP mouse model to understand neuroplasticity : a new therapeutic target for parkinson's disease? / Giselle M. Petzinger [and others] -- MPTP-treated primate, with specific reference to the use of the common marmoset (callitbrix jacchus) / Michael J. Jackson and Peter Jenner -- Behavioral assessment in the african green monkey after MPTP administration / D. Eugene Redmond, Jr.
  • 2015 Springer Protocols
    edited by Jerome Y. Yager.
    1. Unilateral common carotid artery ligation as a model of perinatal asphyxia: the original Rice-Vannucci model -- 2. Bilateral uterine artery ligation (BUAL): placental insufficiency causing fetal growth restriction and cerebral palsy -- 3. Perinatal intracerebral hemorrhage model and developmental disability -- 4. Preterm rabbit model of glycerol-induced intraventricular hemorrhage -- 5. Models of perinatal brain injury in premature and term newborns resulting from gestational inflammation due to inactivated group B streptococcus (GBS), or lipopolysaccharide (LPS) from E. coli and/or immediately postnatal hypoxia-ischemia (HI) -- 6. Fetal brain activity in the sheep model with intrauterine hypoxia -- 7. Studies of perinatal asphyxial brain injury in the fetal sheep -- 8, The sheep as a model of brain injury in the premature infant -- 9. The rabbit as a model of cerebral palsy -- 10. A newborn piglet survival model of post-hemorrhagic ventricular dilatation (PHVD) -- 11. Physiologic aspects of the piglet as a model of neonatal hypoxia and reoxygenation -- 12. The newborn pig global hypoxic-ischemic model of preinatal brain and organ injury -- 13. Animal models of fetal alcohol spectrum disorder -- 14. Modeling intellectual disability in drosophila -- 15. Animal models of cerebral dysgenesis: excitotoxic brain injury -- 16. The effect of age on brain plasticity in animal models of developmental disability -- Index.
  • 2016 Springer
    Chi-Chao Chan, editor.
    1. Animal models of herpes keratitis -- 2. Animal models of cataracts -- 3. Animla models of glaucoma -- 4. Animal models of age-related macular degeneration: subretinal inflammation -- 5. Animal models of diabetic retinopathy -- 6. Animal models of autoimmune uveitis -- 7. Animal models of retinitis pigmentosa (RP) -- 8. An animla model of Graves' orbitopathy -- 9. Animal models of ocular tumors -- 10. Epilogue -- Index.
  • 2011 Springer Protocols
    edited by Chao Ma, Jun-Ming Zhang.
    Assessment of pain in animals / Wenrui Xie -- Animal models of inflammatory pain / Rui-Xin Zhang and Ke Ren -- Animal models of visceral pain / Karin N. Westlund -- Animal models of pain after peripheral nerve injury / Lintao Qu and Chao Ma -- Animal models of pain after injury to the spinal ganglia and dorsal roots / Xue-Jun Song -- Localized inflammatory irritation of the lumbar ganglia : an animal model of chemogenic low back pain and radiculopathy / Jun-Ming Zhang -- Animal models of central neuropathic pain / Bryan Hains and Louis P. Vera-Portocarrero -- Animal models of cancer pain / Paul W. Wacnik, Cholawat Pacharinsak, and Alvin J. Beitz -- Animal models of diabetic neuropathic pain / Maxim Dobretsov ... [et al.] -- Animal models of HIV-associated painful sensory neuropathy / Sonia K. Bhangoo, Lauren Petty, and Fletcher A. White -- Animal models of postoperative pain / Chaoran Wu ... [et al.].
  • 2011 Springer Protocols
    edited by Patricio O'Donnell.
    Method to the madness : producing the neonatal ventral hippocampal lesion rat model of schizophrenia / R. Andrew Chambers and Barbara K. Lipska -- Gestational MAM (methylazoxymethanol) administration : a promising animal model for psychosis onset / Gwenaelle Le Pen [and others] -- Prenatal infection and immune models of schizophrenia / Alan S. Brown -- Hypoxic rat model for obstetric complications in schizophrenia / Andrea Schmitt [and others] -- Developmental vitamin D (DVD) model of schizophrenia / Darryl W. Eyles [and others] -- Studying schizophrenia in a dish : use of primary neuronal cultures to study the long-term effects of NMDA receptor antagonists on parvalbumin-positive fast-spiking interneurons / M. Margarita Behrens -- Glutathione deficit and redox dysregulation in animal models of schizophrenia / Pascal Steullet [and others] -- Psychiatric genetics and the generation of mutant animal models / P. Alexander Arguello and Joseph A. Gogos -- DISC1 mouse models / Yavuz Ayhan [and others] -- Genetically engineered mice for schizophrenia research / Juan E. Belforte and Kazu Nakazawa -- Epigenetic animal models of GABAergic deficit in mental disorders / Patricia Tueting, Erminio Costa, and Alessandro Guidotti -- Modeling schizophrenia in neuregulin 1 and ErbB4 mutant mice / Yisheng Lu [and others].
  • 2013 Springer
    Santosh A. Helekar, editor.
    Animal Models of Speech and Language Disorders is arguably the first book that integrates several decades of research on the neuroscience and genetics of speech and language with behavioral, systems, cellular and molecular neurobiological studies on animal communication to create a synthesis of ideas with potential translational value in neurology, neurolinguistics and speech science. Speech and language dysfunctions plague a large segment of todays young and old alike because, besides being primary afflictions, they are also an integral part of the complex symptomatology of most of the common neurological and neurodevelopmental disorders, such as stroke, dementia, intellectual disability and autism. It is therefore essential that biomedical research be focused on understanding their neurobiological and genetic bases in order to have the chance of developing rational approaches to treating them. By weaving together findings from diverse disciplines in the comparative biology of vocal communication in songbirds, bats, New World monkeys and the great apes, with the applied and translational perspective in mind, this book attempts to create awareness among researchers and students about the strengths of the comparative and evolutionary approach to the scientific understanding of speech and language, and to addressing intractable clinical problems affecting higher brain functions. Animal Models of Speech and Language Disorders will be highly instructive to researchers, clinicians, advanced speech pathology and neuroscience students, and all those who are interested in the current state of knowledge in the basic and applied aspects of speech and language.
  • 2013 Springer Protocols
    edited by Håkan Aldskogius.
    Spinal cord : functional organization, diseases, and dysfunctions / Pierre A. Guertin -- Pathological findings in traumatic injury to the human spinal cord / Ronald C. Kim -- Acute spinal cord injury in vitro : insight into basic mechanisms / Miranda Mladinic, Andrea Nistri, and Giuliano Taccola -- Spinal cord injury : the lamprey model / Andrew D. McClellan -- Dorsal root injury for the study of spinal cord injury repair / Hakan Aldskogius and Elena N. Kozlova -- No-laminectomy spinal cord-transected murine model / Pierre A. Guertin -- Spinal cord injury : the rabbit model / Nadezda Lukacova, Jaroslav Pavel, and Jan Galik -- Cat model of spinal cord injury / Alain Frigon -- Using naturally occurring spinal cord injury in domestic dogs to explore novel therapeutic options / Nick D. Jeffery, Nicolas Granger, and Robin J.M. Franklin -- Primate models of spinal repair / Corinna Darian-Smith -- Animal models of spinal cord ischemia / Hamdy Awad, Haytham Elgharably, and Phillip Popovich -- Magnetic resonance imaging of experimental spinal cord injury / Laura E. Gonzalez-Lara, Freda Jawan, and Paula J. Foster -- Spinal cord injuries : principles and methods for outcome assessment / Elisabet Akesson, Cinzia Calzarossa, and Erik Sundstrom -- Spinal cord injury : modern clinical management and its correlation to advances in basic science / Anders Holtz [and others].
  • 2012 WHO
    edited by Al Dufour, Jamie Bartram, Robert Bos and Victor Gannon.
    Also available: Print – 2012
  • v. 1-, 2007- Springer
    Phillips, C. J. C.
  • 2008 Springer
    Haynes, Richard P.
  • 2014 Springer Protocols
    edited by Andreas Werner.
    Targeted small noncoding rna-directed gene activation in human cells -- Isolation of chromatoid bodies from mouse testis as a rich source of short RNAs -- Generation of endo-siRNAs in xenopus laevis oocytes -- Analysis of endo-siRNAs in drosophila -- Methods for studying the biological consequences of endo-siRNA deficiency in drosophila melanogaster -- Small RNA library cloning procedure for deep sequencing of specific endogenous siRNA classes in caenorhabditis elegans -- Assays for direct and indirect effects of c. Elegans endo-siRNAs -- Extraction and nonradioactive detection of small RNA molecules -- P19-mediated enrichment and detection of siRNAs -- Detection of small noncoding RNAs by in situ hybridization using probes of 2'-o-methyl RNA + LNA -- Enhanced detection of small RNAs using a nonradioactive approach -- Computing siRNA and piRNA overlap signatures -- Isolation of small interfering RNAs using viral suppressors of RNA interference -- Computational analysis, biochemical purification, and detection of tRNA-derived small RNA fragments -- Differential DNA methylation patterns in endo-siRNAs mediated silencing of LINE-1 retrotransposons.
  • 2014 Springer
    C. Niek van Dijk.
    Ankle injuries are often sport related and pose a diagnostic and therapeutic challenge. Over the past 25 years, Niek van Dijk, founder of the Amsterdam Foot and Ankle School and author of this book, has developed a new philosophy of ankle arthroscopy. It entails a comprehensive approach which includes various diagnostic strategies and the application of a number of minimally invasive endoscopic techniques. The procedures are based on research programs and long-term outcome studies performed at the Orthopaedic Research Center Amsterdam. Use of these techniques has spread throughout the world; they are now recognized as the state of the art and have been used to treat many leading professional athletes. This diagnostic and operating manual presents the Amsterdam Foot and Ankle School approach for a wide variety of ankle and hindfoot problems. Clear step-by-step instructions are provided with the help of numerous high-quality illustrations, most of which are in color. Access to a web-based educational site is also available to readers.
  • 2014 Springer
    Pieter P.R.N. d'Hooghe, Gino M.M.J. Kerhoffs, editors.
    This book creates a unique platform that covers main ankle pathologies specifically related with football. Experiences from professional players have been combined with evidence-based medical content from renowned experts in the field to present a comprehensive picture on ankle injuries in football. Worldwide, ankle injuries present a high burden for sports medicine physicians, physiotherapists, players, and coaches in and around the football pitch. This book contains updated content for both medical and nonmedical individuals involved with football.
  • 2011 Springer
    Joachim Sieper, Jürgen Braun.
    Overview of ankylosing spondylitis -- Clinical manifestations of ankylosing spondylitis -- Diagnosis of ankylosing spondylitis -- Imaging in ankylosing spondylitis -- Management of ankylosing spondylitis -- Socioeconomic aspects of ankylosing spondylitis.
  • 2013 Springer
    Alan Ebringer.
    Ankylosing spondylitis and Klebsiella is a comprehensive and informative text on the cause of Ankylosing spondylitis. Ankylosing spondylitis (AS) is a condition which affects 20 million people worldwide and is likely caused or initiated by a bowel infection from Klebsiella bacteria. When a patient is infected by Klebsiella bacteria, his or her immune system will make antibodies against all the antigens or molecules found in the microbe. Because some of the bacterial antigens resemble self tissues, the anti-bacterial antibodies will attack not only the bacteria but also the self tissues such as the joints and the cells having the same HLA molecules, which is how the disease AS starts. This is the concept of molecular similarity or "molecular mimicry" which previously has been found to work in two other autoimmune diseases; rheumatic fever and rheumatoid arthritis. The first paper on this subject was published in 1976 and since then over 100 papers on rheumatological topics have been published, from Prof Ebringer's group, at the Division of Life Sciences, King's College in London, UK. The relevant information from these papers is extracted and presented in this book format making it accessible to health professionals, research institutions, pharmaceutical companies and universities and the general public.
  • Google Books
    Hagen, Ernst Richard.
    Also available: Print – 1872-
  • Google Books
    Neubauer, C.; Ellinger, Alexander; Huppert, Hugo; Vogel, Julius; Neubauer, C.
    Also available: Print – 1858.
  • 1973-1976.
    compiled by Anne-Laure Bourre.
    Status: Not Checked OutLane Catalog Record
  • 2007
    guest editors: Susan J. Rehm, J. Todd Weber.
  • 1978-
    Santa Clara County Health Systems Agency.
    Status: Not Checked OutLane Catalog Record
  • 1973/74-1975/76.
    Status: Not Checked OutLane Catalog Record
  • 1979-
    Medicines Commission, Committee on Safety of Medicines, Veterinary Products Committee, British Pharmacopoeia Commission, Committee on the Review of Medicines, Committee on Dental and Surgical Materials, and with a report prepared by the Medicines Division of the Department of Health and Social Security.
    Status: Not Checked OutLane Catalog Record
  • nosummary Google Books
    Fulltext (1977) Google Books
    Fulltext (1978) Google Books
    Also available: Print – 1974, 1977-78.
  • 2011- Springer
    Vincent, J. L.
  • 2010 Springer
    edited by Jean-Claude Givel, Neil James Mortensen.
  • 2016 Springer
    Massarat Zutshi, editors.
  • 2006 Springer
    Alexander M. Holschneider, John M. Hutson, editors.
    The results of the Krickenberg Conference, 17-20 May 2005, an international workshop of 26 international authorities on congenital malformations of the organs of the pelvis and perineum are presented.
  • 2006
    Katrina Firlik.
    Status: Not Checked OutLane Catalog Record
  • 2007 ClinicalKey
    editor in chief, Chadwick C. Prodromos ; associate editors, Charles H. Brown [and others].
    Master the very latest clinical and technical information on the full range of anterior cruciate ligament reconstruction techniques. Both inside the remarkably user-friendly printed version of this Expert Consult title and on its fully searchable web site, you'll find detailed coverage of hamstring, allograft and bone-tendon-bone (BTB) ACL reconstruction (including single versus double bundle techniques), and hamstring graft harvesting; plus fixation devices, rehabilitation, revision ACLR surgery, and much more! Surgical technique videos on the bonus DVD help you hone and refine your skill set under the expert guidance of the leading authorities in the field. A "dream team" of ACL surgeons provides the advanced guidance you need to overcome the toughest challenges in this area. A comparison of the full range of graft options for ACL reconstruction makes it easier to choose the best approach for each patient. State-of-the-art information on the latest principles and technical considerations helps you avoid complications. ₁How to' principles of post-op rehabilitation and revision ACL surgery optimize patient outcome. The bonus DVD helps you hone and refine your surgical technique under the expert guidance of a "who's who" in ACL surgery. Access to the full contents of the book online enables you to consult it from any computer and perform rapid searches. Also available in an upgradeable premium online version including fully searchable text PLUS timely updates.
  • 2014 Springer
    Rainer Siebold, David Dejour, Stefano Zaffagnini, editors.
    This practical and instructional guidebook, written by international experts in anterior cruciate ligament (ACL) reconstruction, covers all challenging aspects of ACL rupture in the acute and chronic setting. It covers the latest, spectacular anatomical findings, treatment of partial ACL tears, various techniques for single- and double-bundle ACL reconstruction, and complex ACL revision surgery. Important surgical steps are clearly described with the help of instructive, high-quality photographs. Important tips, tricks, and pitfalls are highlighted and intra- and postoperative complications, rehabilitation, and prevention of re-rupture are discussed. All authors are prominent and experienced ACL surgeons.
  • 2011 Springer
    Vicente Sanchis-Alfonso (editor).
    Background: Patellofemoral Malalignment Versus Tissue Homeostasis Myths and Truths About Patellofemoral Disease -- In Search of the Etiology of Anterior Knee Pain -- Biological Causes of Anterior Knee Pain -- Pathogenesis of Anterior Knee Pain in the Active Young: Is There a Relation Between the Presence of Patellofemoral Malalignment and Pain? What Have We Learned from Realignment Surgery? -- Unilateral Anterior Knee Pain as a Sign of Knee Asymmetry -- Biomechanical Bases for Anterior Knee Pain and Patellar Instability -- Anatomy of Patellar Dislocation -- Evaluation of the Patient with Anterior Knee Pain and Patellar Instability -- Influence of Psychological Factors on Pain and Disability in Anterior Knee Pain Patients -- Uncommon Causes of Anterior Knee Pain -- Risk Factors and Prevention of Anterior Knee Pain -- Non-operative Treatment of Athletes with Anterior Knee Pain: Science, Classical, and New Ideas -- Conservative Management of Anterior Knee Pain: The McConnell Program -- Skeletal Malalignment and Anterior Knee Pain: Rationale, Diagnosis, and Management -- Patellar Tendinopathy: Where Does the Pain Come From? -- Biochemical Causes of Patellar Tendinopathy? -- The Pathophysiology of Patellofemoral Arthritis -- Prevention of Anterior Knee Pain After Anterior Cruciate Ligament Reconstruction -- Anterior Knee Pain with Special Emphasis on the Clinical, Radiographic, Histological, Ultrastructural, and Biochemical Aspects After Anterior Cruciate Ligament Reconstruction Using Autografts -- Imaging and Musculoskeletal Modeling to Investigate the Mechanical Etiology of Patellofemoral Pain -- Computational Models for Investigating the Patellofemoral Joint: Clinical Relevance. Kinetic Analysis: A Sensitive Outcome Objective Measurement Method in Evaluating Lateral Patellar Instability A Preliminary Study -- Kinetic and Kinematic Analysis in Evaluating Patients with Anterior Knee Pain -- Failure of Patellofemoral Surgery: Analysis of Clinical Cases -- Neuromatous Knee Pain: Evaluation and Management -- Kinetic and Kinematic Analysis of Iatrogenic Medial Patellar Instability: Clinical Relevance -- Ultrasound and Doppler-Guided Arthroscopic Shaving for the Treatment of Patellar Tendinopathy/Jumper's Knee: Biological Background and Description of Method -- Arthroscopic Patellar Denervation for Anterior Knee Pain -- Reconstruction of the Medial Patellofemoral Ligament: How I Do It -- Reconstruction of the Medial Patellofemoral Ligament: How I Do It -- MPFL Reconstruction: Principles and Complications -- Reconstruction of the Lateral Patellofemoral Ligament: How I Do It -- Reconstruction of the Lateral Patellofemoral Ligament: How I Do It -- Osteotomies Around the Patellofemoral Joint -- Sulcus Deepening Trochleoplasty -- Rotational Tibial Osteotomy -- Rotational Femoral Osteotomy -- Patella Infera and Patella Alta -- Combined Tibial Tubercle Realignment and MPFL Reconstruction -- Anteromedial Tibial Tubercle Osteotomy (Fulkerson Osteotomy) -- The Patella Thinning Osteotomy: A New Technique for Patellofemoral Arthritis -- Cartilage Restoration in the Patellofemoral Joint -- Autologous Osteochondral Mosaicplasty -- Patellofemoral Allografts -- Patellofemoral Arthroplasty: Pearls and Pitfalls -- The Patellofemoral Arthroplasty: The Great Solution, the Great Problem -- A Philosophy of the Patellofemoral Joint: A Logical Clinical Approach -- Epilogue.
  • 2006 Springer
    Vicente Sanchis-Alfonso (ed.).
  • 2008 ClinicalKey
    by Marian S. Macsai, Bruno Machado Fontes.
    Developmental anomalies of the anterior segment -- Disorders of the tear film -- Conjunctiva -- Episclera and sclera -- Cornea -- Iris and ciliary body.
  • 2014 CRCnetBASE
    edited by Taylor C. Wallace, M. Monica Giusti.
  • 2008
    Status: Not Checked OutLane Catalog Record
  • 2009
    [edited by] Robert A. Hahn, Marcia C. Inhorn.
    Status: Not Checked OutLane Catalog Record
  • 2012
    Anamaria Iosif Ross.
    Alternative medicine is not a fashionable new trend, but an established cultural strategy as well as a dynamic feature of mainstream contemporary medicine, in which elements of folk traditions are often blended with Western scientific approaches. This is a concise yet wide-ranging exploration of non-biomedical healing. The book addresses a broad range of practices including: substance, energy and information flows (such as helminthic therapy); spirit, consciousness and trance (shamanism, for example); body, movement and the senses (reiki and aromtherapy); as well as classical medical traditions as complements or alternatives to Western biomedicine (such as Ayurveda). The book explores the cultural underpinnings of contemporary healing methods, while assessing current ideas, topics and resources for further study.
  • 2015 Wiley
    edited by Delminda Neves.
    Human ageing, a biological view / Henrique de Almeida and Liliana Matos -- To eat or not to eat : anti-ageing effects of energy restriction / Delminda Neves, Maria Joao Martins, Emanuel dos Passos and Ines Tomada -- Nutrition, epigenetics and ageing / Jill McKay and Luisa A. Wakeling -- Nutritional intervention in age-related genetic and epigenetic instability and cancer / Thomas Ong and Ana Paula de Melo Loureiro -- Nutraceuticals in immunosenescence / Thea Magrone and Emilio Jirillo -- Cardiovascular ageing / Carmen Bras Silva and Delminda Neves -- Bone and muscle ageing / Joana Carvalho, Elisa Marques and Pedro Moreira -- Nutrition and the ageing eye / Angela Carneiro -- Nutrition modulation of skin ageing / Alessandra Marini and Jean Krutmann -- Retarding brain ageing and cognitive decline / Jose Paulo Andrade -- Science-based anti-ageing nutritional recommendations / Ines Tomada and Jose Paulo Andrade.
  • 2014 ScienceDirect
    edited by Atta-ur-Rahman, FRS, and Muhammad Iqbal Choudhary.
    The inhibition of angiogenesis is an effective mechanism of slowing down tumor growth and malignancies. The process of induction or pro-angiogenesis is highly desirable for the treatment of cardiovascular diseases, wound healing disorders, and more. Efforts to understand the molecular basis, both for inhibition and induction, have yielded fascinating results. Originally published by Bentham and now distributed by Elsevier, Anti-Angiogenesis Drug Discovery and Development, Volume 2 is an compilation of well-written reviews on various aspects of the anti-angiogenesis process. These reviews have been contributed by leading practitioners in drug discovery science and highlight the major developments in this exciting field in the last two decades. These reader-friendly chapters cover topics of great scientific importance, many of which are considered significant medical breakthroughs, making this book excellent reading both for the novice as well as for expert medicinal chemists and clinicians.
  • 2008 Springer
    edited by Beverly A. Teicher, Lee M. Ellis.
  • 2008 CRCnetBASE
    edited by Darren W. Davis and Roy S. Herbst, James L. Abbruzzese
    Part I: Angiogenesis in cancer -- Strategies to prolong the nonangiogenic dormant state of human cancer / George N. Naumov and Judah Folkman -- Vascular endothelial growth factor: basic biology and clinical implications / Napoleone Ferrara -- Angiogenesis in solid tumors / Rakesh K. Jain and Dan G. Duda -- Pathophysiologic role of VEGF in hematologic malignancies / Klaus Podar ... [et al.] -- Tumor microenvironment and angiogenesis / Cheryl H. Baker and Isaiah J. Fidler -- Part II: Targeting angiogenesis for cancer therapy -- Tyrosine kinase inhibitors of angiogenesis / Janessa J. Laskin and Alan B. Sandler -- Development of antiangiogenic monoclonal antibodies for cancer therapy / Zhenping Zhu and Daniel J. Hicklin -- Targeting fibroblast growth factor / fibroblast growth factor receptor system in angiogenesis / Marco Rusnati and Marco Presta -- Development of the VEGF trap as a novel antiangiogenic treatment currently in clinical trials for cancer and eye diseases, and discovery of the next generation of angiogenesis targets / John S. Rudge ... [et al.] -- Proteinases and their inhibitors in angiogenesis / Yves A. DeClerck, Khalid Bajou, and Walter E. Laug -- Prostaglandins and COX-2: role in antiangiogenic therapy / Kristin Hennenfent, Daniel Morgensztern, and Ramaswamy Govindan -- Integrins, adhesion, and coadhesion inhibitors in angiogenesis / Abebe Akalu and Peter C. Brooks -- Conventional therapeutics with antiangiogenic activity / Christian Hafner, Thomas Vogt, and Albrecht Reichle -- Vascular disrupting agents / David J. Chaplin, Graeme J. Dougherty, and Dietmar W. Siemann -- Vascular and hematopoietic stem cells as targets for antiangiogenic therapy / Carlos Almeida Ramos, Hans-Georg Kopp, and Shahin Rafii -- Genetic strategies for targeting angiogenesis / Anita Tandle, Mijung Kwon, and Steven K. Libutti -- Identification of new targets using expression profiles / Thomas R. Burkard ... [et al.].; Part III: Translating angiogenesis inhibitors to the clinic -- Clinical trial design and regulatory issues / Ramzi N. Dagher and Richard Pazdur -- Surrogate markers for antiangiogenic cancer therapy / Darren W. Davis -- Noninvasive surrogates / Bruno Morgan and Mark A. Horsfield -- Pharmacodynamic markers in tissues / Darren W. Davis -- Blood-based biomarkers for VEGF inhibitors / Amado J. Zurita, Hua-Kang Wu, and John V. Heymach -- Part IV: Treatment of specific cancers with angiogenesis inhibitors -- Antiangiogenic therapy for colorectal cancer / Paulo M. Hoff and Everardo D. Saad -- Combined modality therapy of rectal cancer / Christopher G. Willett and Dan G. Duda -- Antiangiogenic therapy for breast cancer / Pablo M. Bedano ... [et al.] -- Antiangiogenic therapy for lung malignancies / David J. Stewart -- Antiangiogenic therapy for prostate cancer / Leslie K. Walker, Glenn Liu, and George Wilding -- Antiangiogenic therapy for hematologic malignancies / Karen W.L. Yee and Francis J. Giles -- Antiangiogenic therapy for gliomas / Heinrich Elinzano and Howard A. Fine -- Antiangiogenic therapy for Kaposi's sarcoma / Henry B. Koon, Liron Pantanowitz, and Bruce J. Dezube -- Antiangiogenic therapy for melanoma / Keith Dredge and Angus G. Dalgleish -- Sunitinib and renal cell carcinoma / Robert J. Motzer and Sakina Hoosen.
  • 2007 CRCnetBASE
    edited by Jack N. Losso, Fereidoon Shahidi, and Debasis Baghchi.
    Part I. History and Scope of Functional Foods Around the World -- Chapter 1. Scope of Conventional and Functional Foods in the U.S.A. / Jack N. Losso -- Chapter 2. Functional Foods, Nutraceuticals and Natural Health Products in Canada / Kelley Fitzpatrick and Fereidoon Shahidi -- Chapter 3. History and Scope of Functional Foods in Japan / Makoto Shimizu and Asami Kawakami -- Chapter 4. Functional Foods in India: History and Scope / Thomas Paul Devasagayam, Jai C. Tilak, and Rekha Singhal -- Chapter 5. History and Scope of Functional Foods in China / Anthony Y.H. Woo, Y. Zhao, R. Zhang, C. Zhou, and Christopher H.K. Cheng -- Chapter 6. History and Current Status of Functional Foods in Korea / Hyong Joo Lee and Young-Joon Surh -- Chapter 7. Australia and New Zealand / Harjinder Singh, Linda Tapsell, Mike Gidley, Pramod Gopal, and Paul J. Moughan -- Chapter 8. Prophylactic Phenolic Antioxidants in Functional Foods of Tropical Island States of the Mascarene Archipelago (Indian Ocean) / T. Bahorun, V. S. Neergheen, M. A. Soobrattee, V. A. Luximon-Ramma, and O. I. Aruoma -- Chapter 9. Functional Foods in Mediterranean and Middle Eastern Countries: History, Scope and Dietary Habits / Fatih Yildiz, Paterna Kotzekidou, Alexandra-Maria Michaelidou, and Giuseppe Nocella -- Chapter 10. Functional Foods in the European Union / Andreu Palou, Paula Oliver, Ana Ma Rodríguez, and Antoni Caimari -- Chapter 11. Functional Foods in the European Union: Main Issues and Impact on the Food Industry / Maurizio Canavari, Alessandra Castellini, Giuseppe Nocella, and Carlo Pirazzoli -- Chapter 12. Functional Foods Legislation in Brazil / Franco M. Lajolo and Eliane Miyazaki Part II. The “Ohmics” Technologies and Functional Foods -- Chapter 13. Principles of Proteomics / Lianji Jin, Lenore Polo Rodicio, and Patrick A. Limbach -- Chapter 14. Toxicogenomics and Systems Toxicology / Michael D. Waters and Jennifer M. Fostel -- Part III. Angiogenesis and Chronic Degenerative Diseases -- Chapter 15. Endothelial Cell Responses to Physiological and Pathophysiological Environments / R.W. Siggins and C.A. Hornick -- Chapter 16. Angiogenic Switch: Roles of Estrogenic Compounds / Sushanta K. Banerjee, Gibanananda Ray, Peter Van Veldhuizen, and Snigdha Banerjee -- Chapter 17. Reactive Oxygen Species and Angiogenesis / Shampa Chatterjee -- Chapter 18. Angiogenesis in Inflammatory Arthritis / Saptarshi Mandal, Smriti Kana kundu-Raychaudhuri, and Siba P. Raychaudhuri -- Chapter 19. Angiogenesis and Cardiovascular Diseases / Robert J. Tomanek -- Chapter 20. Angiogenesis and Anti-Angiogenesis in Brain Tumors / Roland H. Goldbrunner -- Chapter 21. Diabetes and Angiogenesis / Golakoti Trimurtulu, Somepalli Venkateswarlu, and Gottumukkala V. Subbaraju -- Chapter 22. Obesity and Angiogenesis / Debasis Bagchi, Shirley Zafra-Stone, Chandan K. Sen, and Manashi Bagchi -- Part IV. Angiogenesis, Functional, and Medicinal Foods -- Chapter 23. Screening Functional Foods as Inhibitors of Angiogenesis Biomarkers / Jack N. Losso -- Chapter 24. Role of Edible Berry Anthocyanins in Angiogenesis / Manashi Bagchi, Shirley Zafra-Stone, Jack N. Losso, Chandan K. Sen, Sashwati Roy, Soumyadipta Hazra, and Debasis Bagchi -- Chapter 25. Redox Regulation of Angiogenesis: Anti-Angiogenic Properties of Edible Berries and Its Significance -- in a Clinical Setting / Gayle M. Gordillo, Debasis Bagchi, and Chandan K. Sen -- Chapter 26. A Novel Nutrient Mixture Containing Ascorbic Acid, Lysine, Proline, and Green Tea Extract Inhibits Critical Parameters in Angiogenesis / M. Waheed Roomi, V. Ivanov, T. Kalinovsky, A. Niedzwiecki, and M. Rath -- Chapter 27. Angiogenesis and Chinese Medicinal Foods / Anthony Y. H. Woo, Y. Zhao, R. Zhang, C. Zhou, and Christopher H. K. Cheng -- Chapter 28. Disposition and Metabolism of Dietary Flavonoids / Min Jung Kang and Dong-Hyun Kim.
  • 2010 ClinicalKey
    [edited by] Roger Finch ... [et al.].
    1. Historical introduction -- 2. Modes of action -- 3. The problem of resistance -- 4. Pharmacodynamics of anti-infective agents: target delineation and susceptibility breakpoint selection -- 5. Antimicrobial agents and the kidneys -- 6. Drug interactions involving anti-infective agents -- 7. Antibiotics and the immune system -- 8. General principles of antimicrobial chemotherapy -- 9. Laboratory control of antimicrobial therapy -- 10. Principles of chemop rophylaxis -- 11. Antibiotic policies -- 12. Aminoglycosides and aminocyclitols -- 13. β-Lactam antibiotics : cephalosporins -- 14. β-Lactam antibiotics: penicillins -- 15. Other β-lactam antibiotics -- 16. Chloramphenicol and thiamphenicol -- 17. Diaminopyrimidines -- 18. Fosfomycin and fosmidomycin -- 19. Fusidanes -- 20. Glycopeptides -- 21. Lincosamides -- 22. Macrolides -- 23. Mupirocin -- 24. Nitroimidazoles -- 25. Oxazolidinones -- 26. Quinolones -- 27. Rifamycins -- 28. Streptogramins -- 29. Sulfonamides -- 30. Tetracyclines -- 31. Miscellaneous antibacterial agents -- 32. Antifungal agents -- 33. Antimycobacterial agents -- 34. Anthelmintics -- 35. Antiprotozoal agents -- 36. Antiretroviral agents -- 37. Other antiviral agents -- 38. Sepsis -- 39. Abdominal and other surgical infections -- 40. Infections associated with neutropenia and transplantation -- 41. Infections in intensive care patients -- 42. Infections associated with implanted medical devices -- 43. Antiretroviral therapy for HIV -- 44. Infections of the upper respiratory tract -- 45. Infections of the lower respiratory tract -- 46. Endocarditis -- 47. Infections of the gastrointestinal tract -- 48. Hepatitis -- 49. Skin and soft-tissue infections -- 50. Bacterial infections of the central nervous system -- 51. Viral infections of the central nervous system -- 52. Bone and joint infections -- 53. Infections of the eye -- 54. Urinary tract infections -- 55. Infections in pregnancy -- 56. Sexually transmitted diseases -- 57. Leprosy -- 58. Tuberculosis and other mycobacterial infections -- 59. Superficial and mucocutaneous mycoses -- 60. Systemic fungal infections -- 61. Zoonoses -- 62. Malaria -- 63. Other protozoal infections -- 64. Helminthic infections.
  • 2012 Springer
    Thomas J. Dougherty, Michael J. Pucci, editors.
  • 2011 Springer
    Ian M. Gould, Jos W.M. van der Meer, editors.
  • 2007 Springer
    edited by Ian M. Gould and Jos W.M. van der Meer.
  • 2012 Springer
    edited by Anthony R.M. Coates.
    Introduction to antibiotic resistance/ Richard Bax, David Griffin -- The origins of antibiotic resistance/ Gerard D. Wright -- Surveillance programmes and antibiotic resistance: worldwide and regional monitoring of antibiotic resistance trends/ Stephen Hawser -- Current and future challenges in the development of antimicrobial agents/ Robert P. Rennie -- The role of the outer membrane of gram-negative bacteria in antibiotic resistance: Ajax' shield or Achilles' heel?/ Malcolm G.P. Page -- Prevention of drug resistance by combined drug treatment of tuberculosis/ Denis A. Mitchison -- Nonmultiplying bacteria are profoundly tolerant to antibiotics / Yanmin Hu, Anthony Coates -- Persister cells: molecular mechanisms related to antibiotic tolerance / Kim Lewis -- Antimicrobial textiles / J. Vaun McArthur, R.C. Tuckfield, C. Baker-Austin -- Efflux: how bacteria use pumps to control their microenvironment / E. David G. McIntosh -- Antibiotics in phase II and III clinical trials / Anthony R.M. Coates, Gerry Halls.
  • 2015
    This brief provides an overview of antibiotic resistance, including a summary of its current impact, the factors that contribute to its spread, and the policy recommendations put in place by federal and global public health agencies. It also reviews the debate around the regulation of antibiotic use in agriculture and examines new developments in policy and research associated with multidrug-resistant bacterial diseases and their underlying causes.
  • v. 1-2, 1949.
    by H.W. Florey ... [et al.].
    Status: Not Checked OutLane Catalog Record
  • ebrary
    Jason C. Gallagher, Conan MacDougall ; senior acquisitions editor, Katey Birtcher ; cover design, Michael O'Donnell.
    Part 1. Considerations with antibiotic therapy -- Part 2. Antibacterial drugs -- Part 3. Antimycobacterial drugs -- Part 4. Antifungal drugs -- Part 5. Antiviral drugs -- Part 6. Antiparasitic Drugs -- Appendix 1. Selected normal human flora -- Appendix 2. Spectrum of activity -- Appendix 3. Empiric regimens for common infections -- Index.
  • 1985-
    volume editor, E. Tomlinson ; co-editor, A. Regosz.
    Status: Not Checked OutLane Catalog Record
    v. 1. [Beta]-lactam antibiotics.
  • 2010 Springer
    David M. Shlaes.
  • v. 7, [2002] CRCnetBASE
    edited by Maurizio Zanetti, J. Donald Capra.
    Also available: Print – v. 1, 1995.
  • 2012 Springer Protocols
    edited by Patrick Chames.
    1. Use of IMGT® databases and tools for antibody engineering and humanization / Marie-Paule Lefranc, Franc̦ois Ehrenmann, Chantal Ginestoux, Véronique Giudicelli, and Patrice Duroux -- 2. Computer-assisted modeling of antibody variable domains / Oscar H.P. Ramos -- 3. Cloning single-chain antibody fragments (scFv) from hyrbidoma cells / Lars Toleikis and André Frenzel -- 4. Human in-cell scFv library from infiltrating B cell / Sylvie Peraldi-Roux -- 5. Construction of human naive antibody gene libraries / Michael Hust, Andreí Frenzel, Torsten Meyer, Thomas Schirrmann, and Stefan Dübel -- 6. Synthetic customized scFv libraries / Gautier Robin and Pierre Martineau -- 7. Selection of stable scFv antibodies by phage display / Eeva-Christine Brockmann -- 8. Generation of single domain antibody fragments derived from camelids and generation of manifold constructs / Cécile Vincke, Carlos Gutiérrez, Ulrich Wernery, Nick Devoogdt, Gholamreza Hassanzadeh-Ghassabeh, and Serge Muyldermans -- 9. Generation and isolation of target-specific single-domain antibodies from shark immune repertoires / Mischa Roland Müller, Ronan O'Dwyer, Marina Kovaleva, Fiona Rudkin, Helen Dooley, and Caroline Jane Barelle -- 10. Generation of human single domain antibody repertoires by Kunkel mutagenesis / Romain Rouet, Kip Dudgeon, and Daniel Christ -- 11. Phage display and selections on purified antigens / Julie Matz and Patrick Chames -- 12. Phage display and selections on cells / Klervi Even-Desrumeaux and Patrick Chames -- 13. Humanization by CDR grafting and specificity-determining residue grafting / Jin Hong Kim and Hyo Jeong Hong -- 14. Humanization by guided selections / Sang Jick Kim and Hyo Jeong Hong -- 15. Selection of antibody fragments by yeast display / Nathalie Scholler -- 16. Evolution of antibodies in vitro by ribosome display / Bryan M. Edwards and Mingyue He -- 17. Mammalian cell surface display of full length IgG / Chen Zhou and Wenyan David Shen -- 18. Production of antibody fragments in Escherichia coli / Tomohisa Katsuda, Hiroyuki Sonoda, Yoichi Kumada -- 19. Production of antibody derivatives in the methylotrophic yeast Pichia pastoris / Steve Schoonooghe, Jannick Leoen, and Jurgen Haustraete -- 20. Monoclonal antibody expression in mammalian cells / Richard Yi Zhang and Wenyan David Shen -- 21. Production of recombinant antibodies in Drosophila melanogaster S2 cells / Daniel X. Johansson, Thomas Krey, and Oskar Andersson -- 22. Production of antibody fragments using the baculovirus-insect cell system / Takanori Furuta, Takafumi Ogawa, and Hideki Yamaji -- 23. Transient and stable expression of antibodies in Nicotiana species / Freydoun Garabagi, Michael D. McLean, and J. Christopher Hall -- 24. Measuring antibody-antigen binding kinetics using surface plasmon resonance / Stephen Hearty, Paul Leonard, and Richard O'Kennedy -- 25. Affinity determination of biotinylated antibodies by flow cytometry / Klervi Even-Desrumeaux and Patrick Chames -- 26. Affinity maturation of antibodies : optimized methods to generate high-quality scFv libraries and isolate IgG candidates by high-throughput screening / Laurence Renaut, Céline Monnet, Olivier Dubreuil, Ouafa Zaki, Fabien Crozet, Khalil Bouayadi, Hakim Kharrat, and Philippe Mondon -- 27. Affinity maturation by semi-rational approaches / Rodrigo Barderas, Johan Desmet, Philippe Alard, and J. Ignacio Casal -- 28. Molecular scanning : combining random mutagenesis, ribosome display, and bioinformatic analysis for protein engineering / Alfredo Darmanin-Sheehan, William James Jonathan Finlay, Orla Cunningham, and Brian Joseph Fennell -- 29. Fucose-targeted glycoengineering of pharmaceutical cell lines / Christiane Ogorek, Ingo Jordan, Volker Sandig, and Hans Henning von Horsten -- 30. Fc engineering : design, expression, and functional characterization of antibody variants with improved effector function / Stefanie Derer, Christian Kellner, Sven Berger, Thomas Valerius, and Matthias Peipp -- 31. Fc engineering : serum half-life modulation through FcRn binding / Tove Olafsen -- 32. Monoclonal antibody lead characterization : in vitro and in vivo methods / Axel Hernandez, Julie Parmentier, Youzhen Wang, Jane Cheng, and Gadi Gazit Bornstein -- 33. Production, purification, and characterization of scFv TNF ligand fusion proteins / Andrea Fick, Agnes Wyzgol, and Harald Wajant --34. Antibody-IL2 fusion proteins for tumor targeting / Andreas A. Hombach and Hinrich Abken -- 35. Recombinant immunotoxins with low endotoxins for clinical and animal studies / Masanori Onda -- 36. Chimeric antigen receptors for T-cell based therapy / Eleanor J. Cheadle, Vicky Sheard, Andreas A. Hombach, Markus Chmielewski, Tobias Riet, Cor Berrevoets, Erik Schooten, Cor Lamers, Hinrich Abken, Reno Debets, and David E. Gilham -- 37. Selection and use of intracellular antibodies (intrabodies) / Sandrine Moutel, Clément Nizak, and Franck Perez -- 38. Radiolabeled antibodies for cancer imaging and therapy / Jacques Barbet, Manuel Bardiès, Mickael Bourgeois, Jean-Franc̦ois Chatal, Michel Chérel, Franc̦ois Davodeau, Alain Faivre-Chauvet, Jean-Franc̦ois Gestin, and Franc̦oise Kraeber-Bodéré -- 39. Design and production of multimeric antibody fragments, focused on diabodies with enhanced and clinical efficacy / Glenn A. Powers, Peter J. Hudson, and Michael P. Wheatcroft -- 40. Production of bispecific antibodies : diabodies and tandem scFv / Nora Hornig and Aline Färber-Schwarz.
  • v. 1-2, 2010. Springer
    v. 2, 2010 Springer
    Roland Kontermann, Stefan Dübel (editors).
  • 2011 Springer
    edited by Mohamed Al-Rubeai.
    Engineered antibodies currently represent over 30 per cent of biopharmaceuticals in clinical trials and their total worldwide sales continue to increase significantly. The importance of antibody applications is reflected in their increasing clinical and industrial applications as well as in the progression of established and emerging production strategies. This volume provides detailed coverage of the generation, optimization, characterization, production and applications of antibody. It provides the necessary theoretical background and description of methods for the expression of antibody in.
  • 2014 ScienceDirect
    Margaret E. Ackerman, Falk Nimmerjahn.
    Antibody Fc is the first single text to synthesize the literature on the mechanisms underlying the dramatic variability of antibodies to influence the immune response. The book demonstrates the importance of the Fc domain, including protective mechanisms, effector cell types, genetic data, and variability in Fc domain function. This volume is a critical single-source reference for researchers in vaccine discovery, immunologists, microbiologists, oncologists and protein engineers as well as graduate students in immunology and vaccinology.
  • 2012 Springer Protocols
    edited by Gabriele Proetzel, Hilmar Ebersbach.
    Antigen presentation for the generation of binding molecules / Hilmar Ebersbach, Gabriele Proetzel, and Chonghui Zhang -- Recombinant antibodies and in vitro selection technologies / C. Ronald Geyer [and others] -- Phage display / Konstantin Petropoulos -- Generation of human fab libraries for phage display / Christoph Rader -- Selection of human fab libraries by phage display / Christoph Rader -- Ribosome Display / George Thom and Maria Groves -- Hybridoma technology for the generation of monoclonal antibodies / Chonghui Zhang -- Application of transgenic mice for therapeutic antibody discovery / E-Chiang Lee and Michael Owen -- Production of human or humanized antibodies in mice / Brice Laffleur [and others] -- Immortalization of human B cells : analysis of B cell repertoire and production of human monoclonal antibodies / Elisabetta Traggiai -- Kinetic screening in the antibody development process / Michael Schraml and Matthias Biehl -- Temperature-dependent antibody kinetics as a tool in antibody lead selection / Michael Schraml and Leopold von Proff -- Determination of antibody glycosylation by mass spectrometry / Christiane Jager [and others] -- Cloning, expression, and purification of monoclonal antibodies in scFv-Fc format / Jiahui Yang and Christoph Rader -- PEGylation of antibody fragments for half-life extension / Simona Jevsevar, Mateja Kusterle, and Maja Kenig -- Bispecific antibody derivatives based on full-length IgG formats / Michael Grote [and others] -- Generation of fluorescent IgG fusion proteins in mammalian Cells / Alexander K. Haas, Klaus Mayer, and Ulrich Brinkmann -- Methods to engineer and identify IgG1 variants with improved FcRn binding or effector function / Robert F. Kelley and Y. Gloria Meng -- Class-specific effector functions of therapeutic antibodies / Virginie Pascal, Brice Laffleur, and Michel Cogne.
  • 2013 Springer Protocols
    edited by Laurent Ducry.
    Antibody-drug conjugate (ADC) clinical pipeline : a review / Ingrid Sassoon and Veronique Blanc -- Antibody-drug conjugate target selection : critical factors / Neil H. Bander -- Selecting an optimal antibody for antibody-drug conjugate therapy : internalization and intracellular localization / Jay Harper ... [et al.] -- Antibody-drug conjugate payloads / Jan Anderl ... [et al.] -- Linker technologies for antibody-drug conjugates / Birte Nolting -- In vivo testing of drug-linker stability / Pierre-Yves Abecassis and Celine Amara -- Pharmacokinetics and ADME characterizations of antibody-drug conjugates / Kedan Lin, Jay Tibbitts, and Ben-Quan Shen -- Safe handling of cytotoxic compounds in a biopharmaceutical environment / Miriam I. Hensgen and Bernhard Stump -- Micro- and mid-scale maleimide-based conjugation of cytotoxic drugs to antibody hinge region thiols for tumor targeting / James E. Stefano ... [et al.] -- Protocols for lysine conjugation / Marie-Priscille Brun and Laurence Gauzy-Lazo -- Engineering THIOMABs for site-specific conjugation of thiol-reactive linkers / Sunil Bhakta, Helga Raab, and Jagath R. Junutula -- Enzymatic antibody modification by bacterial transglutaminase / Patrick Dennler, Roger Schibli, and Eliane Fischer -- Formulation development of antibody-drug conjugates / William J. Galush and Aditya A. Wakankar -- Conjugation process development and scale-up / Bernhard Stump and Jessica Steinmann -- Methods for conjugating antibodies to nanocarriers / Anil Wagh and Benedict Law -- Drug-to-antibody ratio (DAR) by UV/Vis spectroscopy / Yan Chen -- Drug-to-antibody ratio (DAR) and drug load distribution by hydrophobic interaction chromatography and reversed phase high-performance liquid chromatography / Jun Ouyang -- Drug-to-antibody ratio (DAR) and drug load distribution by LC-ESI-MS / Louisette Basa -- Determination of charge heterogeneity and level of unconjugated antibody by imaged cIEF / Joyce Lin and Alexandru C. Lazar -- Risk-based scientific approach for determination of extractables/leachables from biomanufacturing of antibody-drug conjugates (ADCs) / Weibing Ding.
  • 2015 Springer
    Jeffrey Wang, Wei-Chiang Shen, Jennica L. Zaro, editors.
    This authoritative volume provides a holistic picture of antibody-drug conjugates (ADCs). Fourteen comprehensive chapters are divided into six sections including an introduction to ADCs, the ADC construct, development issues, landscape, IP and pharmacoeconomics, case studies, and the future of the field. The book examines everything from the selection of the antibody, the drug, and the linker to a discussion of developmental issues such as formulations, bio-analysis, pharmacokinetic-pharmacodynamic relationships, and toxicological and regulatory challenges. It also explores pharmacoecomonics and intellectual properties, including recently issued patents and the cost analysis of drug therapy. Case studies are presented for the three ADCs that have received FDA approval: gemtuzumab ozogamicin (Mylotarg®), Brentuximab vedotin (Adcetris®), and ado-trastuzumab emtansine (Kadcyla®), as well as an ADC in late-stage clinical trials, glembatumumab vedotin (CDX-011). Finally, the volume presents a perspective by the editors on the future directions of ADC development and clinical applications. Antibody-Drug Conjugates is a practical and systematic resource for scientists, professors, and students interested in expanding their knowledge of cutting-edge research in this exciting field.
  • 2013 Springer
    Gail Lewis Phillips, editor.
    The concept of delivering 'magic bullets' to treat diseases was first proposed by Paul Erlich in the early 1900's. The realization of this concept for the treatment of cancer occurred in the late 1990's with the approval of monoclonal antibody therapies. The use of monoclonal antibodies conjugated (linked) to potent cytotoxic agents (antibody-drug conjugates, ADCs) for specifically delivering cytotoxics to cancer cells was an obvious extension of antibody-based therapy. ADCs have been under intense investigation for several decades; progress, however, has been limited due to toxicity or lack of improved efficacy compared to unconjugated cytotoxics. More recently, linker technology and target selection have advanced such that several ADCs and immunotoxins are undergoing clinical testing or are approved for use. This important volume gives the latest and most comprehensive information on the topic, describing different types of ADCs and immunotoxins for both hematologic and solid malignancies. Finally, the volume highlights the promise that this technology holds for diverse types of human cancer.
  • 2012 CRCnetBASE
    edited by Gordon M. Cragg, David G.I. Kingston, and David J. Newman.
    "This book covers clinically used anticancer agents that are either natural products or are clearly derived from natural product leads. The second edition includes drugs that are currently in development. In addition, the text emphasizes the applications of synthetic and medicinal chemistry to the preparation of analogs with enhanced activities. Contributors also address the potential of novel drug discovery through the use of genome mining as well as the status of advanced development candidates. For each compound of class of compounds, the text provides information on the history, structure, mechanism of action, development, synthesis, medicinal chemistry, and clinical applications"-- Provided by publisher. "The search for new lead compounds is a crucial element of modern pharmaceutical research. Natural products provided the only source of pharmaceuticals for thousands of years, and natural products have made enormous contributions to human health through compounds such as quinine, morphine, aspirin (a natural product analog), digitoxin, and many others. The potential of natural products as anticancer agents was recognized in the 1950's by the U. S. National Cancer Institute (NCI) under the leadership of the late Dr. Jonathan Hartwell, and the NCI has since made major contributions to the discovery of new naturally occurring anticancer agents through its contract and grant support, including an important program of plant and marine collections. Many, although not all, of the compound classes described in the following pages owe their origin in whole or in part to NCI support. In spite of the success of the natural products approach to anticancer drug discovery, as exemplified by the following chapters, in recent years their importance as a source of molecular diversity for drug discovery research and development has been overshadowed by newer chemical approaches currently in favor. These approaches include chemical ones which make heavy use of combinatorial chemistry, and biological ones such as manipulation of biosynthetic pathways of microbial metabolites through combinatorial biosynthetic techniques. It is thus worthwhile to review briefly the major reasons why natural products are so important. First, there is a strong biological and ecological rationale for plants and marine invertebrates to produce novel bioactive secondary metabolites"-- Provided by publisher.
  • 2014 Springer
    Stefan Grimm, editor.
    "This book discusses the emergence of a new class of genes with a specific anticancer activity. These genes, recently defined as "Anticancer Genes", are reviewed in individual chapters on their mode of action, the specific cell death signals they induce, and the status of attempts to translate them into clinical application. Anticancer Genes provides an overview of this nascent field, its genesis, current state, and prospect. It discusses how Anticancer Genes might lead to the identification of a repertoire of signaling pathways directed against cellular alterations that are specific for tumor cells."--Publisher's website.
    Also available: Print – 2014
  • 2012 Springer
    Paul Kosma, Sven Müller-Loennies, editors.
    Many pathogens and aberrant malignant cells express unique carbohydrates on their surface representing attractive targets for vaccine design. Considerable progress has recently been made in the identification of novel carbohydrate based vaccines and a large number has reached clinical phase studies. The success of several licensed carbohydrate based vaccines against bacterial pathogens such as Haemophilus influenzae type b, Neisseria meningitidis or Streptococcus pneumoniae demonstrates their great potential. However, the study of anti-carbohydrate antibodies is technically challenging and partly because of low affinities and promiscuous specificity they have not been medically exploited to full potential. The study of antibody specificities and identification of protective carbohydrate epitopes lies at the heart of successful vaccine design. In addition to therapy, antibodies in general serve as diagnostic tools in medical and scientific laboratories. In this setting high affinity and exquisite specificity are important factors for their successful use. ãaAnticarbohydrate Antibodies ãa from molecular basis to clinical applicationãa compiles current knowledge on the immunological recognition of carbohydrates by the adaptive immune system from a molecular perspective providing fundamental insight needed for advancing clinically relevant diagnostics and therapeutic applications. Based on significant progress in the fields of glycoimmunology and structural biology in recent years, the book comprehensively reviews the state-of-the-art in defining the key elements of carbohydrate recognition by antibodies, the molecular mimicry of carbohydrate epitopes as well as the molecular features leading to specific and relaxed binding modes. Backed-up by a combination of modern technologies to elucidate structural details of carbohydrate-antibody interactions, biomedically important carbohydrate antigens from viral, bacterial, parasite, insect and tumor cells have been analyzed in in-depth reviews written by well-known experts in the field. Fundamental knowledge of these molecular mechanisms eventually provides a rational basis to improve efficacy of carbohydrate-based vaccines and to further refine diagnostic tools in detection of pathogens and malignant cells.
  • 2013
    Diane Tseng.
    Mobilization of the T cell response against cancer has the potential to achieve long-lasting cures. However, it is not known how to optimally harness antigen presenting cells to achieve an effective anti-tumor T cell response. In this study, we show that anti-CD47 antibody-mediated phagocytosis of cancer by macrophages can initiate an anti-tumor T cell immune response. Using the ovalbumin model antigen system, anti-CD47 antibody-mediated phagocytosis of cancer cells by macrophages resulted in increased priming of OT-I T cells (CD8+), but did not prime OT-II T cells (CD4+). The CD4+ T cell response was characterized by a reduction in Foxp3+ regulatory T cells. Macrophages following anti-CD47-mediated phagocytosis primed CD8+ T cells to exhibit cytotoxic effector function in vivo, protecting animals from tumor challenge. We conclude that anti-CD47 antibody treatment not only enables macrophage phagocytosis of cancer, but can also initiate an anti-tumor cytotoxic T cell immune response. Anti-CD47-mediated phagocytosis of cancer cells by macrophages leads to priming of a predominant CD8+ T cell response without priming of CD4+ T cells, demonstrating differential priming of T cell responses by macrophages. Priming of effector CD8+ T cells is difficult to achieve with existing vaccines for cancer and infectious diseases. Anti-CD47-based vaccination strategies serve as a promising new strategy for overcoming this challenge for treating or preventing human disease.
  • 2005 HighWire
    edited by Hans-Christoph Diener, Freek Verheugt.
    Also available: Print – 2005
  • 2004 HighWire
    edited by Freek W.A. Verheugt, Elliot M. Antman.
    Also available: Print – 2004
  • v. 1-2, 1973.
    Contributors: A. Benakis [and others.
    Status: Not Checked OutLane Catalog Record
  • 2012 Future Med
    editor, Dan J. Stein.
    Antidepressants : past, present and future / Dan J. Stein -- Selective-serotonin reuptake inhibitors / Luo L. Wang & Raymond W. Lam -- Serotonin reuptake and receptor blockers / Michael Van Ameringen, Beth Patterson & Elizabeth Lee -- Serotonin noradrenaline reuptake inhibitors / Michel Bourin -- Noradrenaline dopamine-reuptake inhibitors / Peter Silverstone -- Noradrenergic and specific serotonergic antidepressants / Emma Heck & Glenda MacQueen -- Melatonin receptor agonists/5-HT2C antagonists / Sidney H. Kennedy & Sakina J. Rizvi -- Glutamatergic antidepressants / Harish Kalra, Olivia Dean, Seetal Dodd & Michael Berk -- Which therapy for which patient? / Tracy L. Greer, Benji T. Kurian & Madhukar H. Trivedi -- Index.
  • v. 4, 1979.
    Mary L. Forsling.
    Status: Not Checked OutLane Catalog Record
  • 2013 Springer
    P.N. Patsalos.
    Antiepileptic Drug Interactions: A Clinical Guide, Second Edition provides a pocket-sized, systematic description of the most clinically relevant drug interactions that occur between AEDs and also between AEDs and non-AEDs. AEDs are presented alphabetically and by drug class in three sections for easy access: Drug interactions between AEDs; Drug interactions between AEDs and non-AEDs: Interactions affecting AEDs; and Drug interactions between AEDs and non-AEDs: Interactions affected by AEDs. Antiepileptic Drug Interactions: A Clinical Guide, Second Edition should help physicians make more rational choices when polytherapy regimens are indicated and should be of interest to all who treat patients with epilepsy: neurologists and neurosurgeons, trainees at all levels, general practitioners and epilepsy nurse specialists.
  • 2016 Springer
    MJ Eadie, FJE Vajda.
    1. Introduction -- 2. Antipileptic drugs and becoming pregnant -- 3. Antiepileptic drug disposition in pregnancy -- 4. The older antiepileptic drugs -- 5. Commonly used newer antiepileptic drugs -- 6. Antiepileptic drugs sometimes used in pregnancy -- 7. Antiepileptic drugs, epileptic seizures and the foetus -- 8. Antiepileptic drugs and foetal malformations: a possible class effect -- 9. Particular antiepileptic drugs and foetal malformations -- 10. Antiepileptic drugs, cognition and neurodevelopment -- 11. Antiepileptic drug therapy: management issues and pregnancy -- 12. Antiepileptic drugs and pregnancy: the future -- Appendix -- Index.
  • 2013 Springer Protocols
    edited by Peter van Endert.
    Purification of large cytosolic proteases for in vitro assays: 20S and 26S proteasomes -- Analysis of proteasome generated antigenic peptides by mass spectrometry -- Using protease inhibitors in antigen presentation assays -- Kinetic studies of cytoplasmic antigen processing and production of MHC class I ligands -- Assaying peptide translocation by the peptide transporter TAP -- In vitro reconstitution of the MHC class I peptide-loading complex -- Studying mhc class i peptide loading and exchange in vitro -- Measuring synthesis and degradation of MHC class I molecules -- Studying ubiquitination of MHC class I molecules -- Evaluation of viral interference with MHC class I-restricted antigen processing and presentation using a flow cytometry-based approach -- Determining the activity of the transporter associated with antigen processing in the compartments of the secretory pathway -- Biochemical large-scale identification of MHC class I ligands -- Establishing MHC class I peptide motifs -- Quantitating MHC class I ligand production and presentation using TCR-like antibodies -- Biochemical analysis of naturally processed antigenic peptides presented by MHC class I molecules -- Identifying source proteins for MHC class I-presented peptides -- Purification, preparation, and use of chaperone-peptide complexes for tumor immunotherapy -- Recombinant poxviruses: Versatile tools for immunological assays -- Bioinformatics identification of antigenic peptide: Predicting the specificity of major MHC class I and II pathway players -- Evaluating CD8(+) T cell responses in vitro -- Cloning CD8(+) cytolytic T lymphocytes -- Production of CD4(+) and CD8 (+) T cell hybridomas -- Tracking antigen-specific CD8(+) T cells using MHC class I multimers -- The purification of large numbers of antigen presenting dendritic cells from mouse spleen -- Preparation of dendritic cells by in vitro cultures -- Monitoring dendritic cell activation and maturation -- Monitoring the intracellular routing of internalized antigens by immunofluorescence microscopy -- Isolation of a specialized, antigen-loaded early endosomal subpopulation by flow cytometry -- Preparing antigens suitable for cross-presentation assays in vitro and in vivo -- Gene transduction in human monocyte-derived dendritic cells using lentiviral vectors -- Pulse-chase analysis for studies of MHC class II biosynthesis, maturation, and peptide loading -- Assembly of matched [alpha/beta] subunits to HLA class II peptide receptors -- Studying MHC class II peptide loading and editing in vitro -- Study of the allogeneic response induced by endothelial cells expressing hla class ii after lentiviral transduction -- Antigen processing for mhc presentation via macroautophagy -- Studying MHC class II transport in dendritic cells -- In vitro digestion with proteases producing MHC class II ligands -- MHC-II ubiquitination -- Studying MHC class II presentation of immobilized antigen by B lymphocytes -- Production of primary human CD4(+) T cell lines and clones -- Analyzing antigen recognition by natural killer T cells -- Chromatofocusing purification of CD1B-antigen complexes and their analysis by isoelectric focusing.
  • Google Books
    Rooke, Charles.
    Also available: Print – 68th, 1879.
  • Limited to 6 simultaneous users
    Includes information on antimicrobial therapy and alternative therapy when the drug of choice cannot be given. The resource delivers information via review articles, capsule summaries, mini-reviews, and a guided PubMed search to pick up post-publication research.
  • 2007
    David Greenwood, Roger Finch, Peter Davey, Mark Wilcox.
    Status: Not Checked OutLane Catalog Record
  • 2012 Ovid
    Finch, R. G.
    Pt. 1. General properties of antimicrobial agents -- Pt. 2. Resistance to antimicrobial agents -- Pt. 3. General principles of usage of antimicrobial agents -- Pt. 4. Therapeutic use of antimicrobial agents.
  • 2014 Springer
    Tomás G. Villa, Patricia Veiga-Crespo, editors.
    Since penicillin and salvarsan were discovered, a number of new drugs to combat infectious diseases have been developed, but at the same time, the number of multi-resistant microorganism strains is increasing. Thus, the design of new and effective antibacterial, antiviral and antifungal agents will be a major challenge in the next years. This book reviews the current state-of-the-art in antimicrobial research and discusses new strategies for the design and discovery of novel therapies. Topics covered include the use of genetic engineering, genome mining, manipulation of gene clusters, X-ray and neutron scattering as well as the antimicrobial effects of essential oils, antimicrobial agents of plant origin, beta-lactam antibiotics, antimicrobial peptides, and cell-wall-affecting antifungal antibiotics.
  • v. 1-2, 2009. Springer
    v. 2, 2009 Springer
    edited by Douglas Mayers ; section editors, Stephen A. Lerner, Marc Ouellette, Jack D. Sobel.
    v. 1. Mechanisms of drug resistance -- v. 2. Clinical and epidemiological aspects.
  • 2013 Wiley
    David A. Phoenix, Sarah R. Dennison, and Frederick Harris.
    Antimicrobial peptides: their history, evolution, and functional promiscuity -- Cationic antimicrobial peptides -- Anionic antimicrobial peptides -- Graphical techniques to visualize the amphiphilic structures of antimicrobial peptides -- Models for the membrane interactions of antimicrobial peptides -- Selectivity and toxicity of oncolytic antimicrobial peptides.
  • 2016 Springer
    Jürgen Harder, Jens-M. Schröder, editors.
    Antimicrobial peptides in cutaneous wound healing -- Antimicrobial peptides as endogenous antibacterials and antivirals at the ocular surface -- Function of antimicrobial peptides in lung innate immunity -- Role of antimicrobial peptides to prevent infections in the kidney and urinary tract -- Antimicrobial peptides in the gut -- Metal sequestration: An important contribution of antimicrobial peptides to nutritional immunity -- Regulation of antimicrobial peptide gene expression by vitamin D -- Dichotomous roles of cationic polypeptides targeting HIV -- Antimicrobial peptides in host-defense: functions beyond antimicrobial activity.
  • 2006 Springer
    W.M. Shafer (ed.).
    Paneth cell [alpha]-defensin synthesis and function / A.J. Ouellette -- Immunomodulatory properties of defensins and cathelicidins / D.M.E. Bowdish, D.J. Davidson, and R.E.W. Hancock -- Host antimicrobial defence peptides in human disease / B. Agerberth and G.H. Guðmundsson -- Antimicrobial peptides: an essential component of the skin defensive barrier / M.H. Braff and R.L. Gallo -- Antimicrobial peptides versus invasive infections / M.R. Yeaman and A.S. Bayer -- Antimicrobial peptides in the airway / D.M. Laube ... [et al.] -- Hepcidin: a peptide hormone at the interface of innate immunity and iron metabolism / T. Ganz -- Innate host defense of human vaginal and cervical mucosae / A.M. Cole -- Molecular mechanisms of bacterial resistance to antimicrobial peptides / D. Kraus and A. Peschel -- Bacterial evasion of antimicrobial peptides by biofilm formation / M. Otto.
    Also available: Print – 2006
  • 2013 Springer
    edited by Pieter S. Hiemstra, Sebastian A.J. Zaat.
    Evolution of Antimicrobial Peptides: A View from the Cystine Chapel -- Innate Immunity in Plants: The Role of Antimicrobial Peptides -- Antimicrobial Peptides Produced by Microorganisms -- LL-37: An Immunomodulatory Antimicrobial Host Defence Peptide -- Wound Repair and Antimicrobial Peptides -- WAPing Out Pathogens and Disease in the Mucosa: Roles for SLPI and Trappin-2 -- Histatins: Multifunctional Salivary Antimicrobial Peptides -- Structure-Function Relationships of Antimicrobial Chemokines -- Mechanisms and Significance of Bacterial Resistance to Human Cationic Antimicrobial Peptides -- Antimicrobial Peptides and Inflammatory Bowel Disease -- Cystic Fibrosis and Defective Airway Innate Immunity -- Antimicrobial Peptides in Chronic Obstructive Pulmonary Disease -- Host Defense Peptides: Immune Modulation and Antimicrobial Activity In Vivo -- Helping the Host: Induction of Antimicrobial Peptides as a Novel Therapeutic Strategy Against Infections.
    Also available: Print – 2013
  • 2010 Karger
    volume editor, J. Todd Weber.
    Community-associated methicillin resistant staphylococcus aureus / Miller, L.G. -- Infections with organisms producing extended-spectrum [beta]-lactamase / Paterson, D.L., Doi, Y. -- Fluoroquinolone resistance : challenges for disease control / Parry, C.M. -- Antibiotic resistance and community-acquired pneumonia during an influenza pandemic / Moore, M.R., Whitney, C.G. -- Promoting appropriate antimicrobial drug use in the outpatient setting : what works? / Belongia, E.A., Mangione-Smith, R., Knobloch, M.J. -- Reducing antimicrobial-resistant infections in health care settings : what works? / Rezai, K., Weinstein, R.A. -- Cost of antimicrobial resistance in healthcare settings : a critical review / Merz, L.R., Guth, R.M., Fraser, V.J. -- Mass treatment of parasitic disease : implications for the development and spread of anthelmintic resistance / Curcher, T.S. ... [et al.] -- Antifungal drug resistance : clinical importance, in vitro detection and implications for prophylaxis and treatment / Arthington-Skaggs, B.A., Frade, J.P. -- Preparing for HIV drug resistance in the developing world / Bennett, D.E.
  • 2014 WHO
    World Health Organization.
    This report examines, for the first time, the current status of surveillance and information on antimicrobial resistance (AMR) at country level worldwide, with particularly attention to antibacterial resistance.
    Also available: Print – 2014
  • 2008
    edited by Robert C. Owens, Jr., Ebbing Lautenbach.
    Status: Not Checked OutLane Catalog Record
    Emerging resistance among candida species : trends and treatment considerations for candidemia -- Early appropriate empiric therapy and antimicrobial de-escalation / James M. Hollands ... [et al.] -- Antimicrobial cycling strategies programs / Bernard C. Camins and Victoria J. Fraser -- Antimicrobial stewardship : rationale for and practical considerations of programmatic institutional efforts to optimize antimicrobial use / Robert C Owens, Jr. -- Computer-assisted programs to optimize antimicrobial use / Stanley L. Pestotnik and Jonathan B. Olson -- Practical application of pharmacodynamic principles to optimize therapy and treat resistant organisms : a focus on beta-lactam antibiotics / Thomas P. Lodise, Ben M. Lomaestro, and George L. Drusano -- Shorter course antibiotic therapy (SCAT) : principles, current data, and caveats / Donald E. Craven ... [et al.] -- Impact of guidelines on antimicrobial treatment of respiratory tract infections / Thomas M. File -- The impact of hospital epidemiology on the management and control of antimicrobial resistance : issues and controversies / August J. Valenti -- Combination antimicrobial therapy for gram-negative infections : what is the evidence? / Nasia Safdar and Cybele L. Abad -- Antibiotic resistance : modern principles and management strategies to optimize outpatient use of antibiotics / Sharon B. Meropol and Joshua P. Metlay. The attributable costs of resistant infections in hospital settings: economic theory and application / R. Douglas Scott II and Rebecca R. Roberts -- Benchmarking : its utility in the fight against antibacterial resistance / Sujata M. Bhavnani and Glenn S. Tillotsen -- Antibiotic resistance : opportunity or obstacle for the pharmaceutical industry? / Glenn S. Tillotsen -- Understanding studies of resistant organisms : focus on epidemiological methods / Ebbing Lautenbach -- Staphylococcus aureus : resistance update and treatment options / Pamela A. Moise and George Sakoulas -- Enterococci : resistance update and treatment options / Peter K. Linden -- Streptococcus pneumoniae : resistance update and treatment options / Nicole Akar, William R. Bishai, and Sanjay K. Jain -- Acinetobacter species : resistance update and treatment options / Lisa L. Maragakis and Trish M. Perl -- Pseudomonas aeruginosa : an understanding of resistance issues / Karen Lolans, Maria Virginia Villegas, and John P. Quinn -- Problematic beta-lactamases : an update / Marion S. Helfand and Louis B. Rice -- Clostridium difficile-infection : overview and update with a focus on antimicrobial resistance as a risk factor / Robert C. Owens, Jr., August J. Valenti, and Mark H. Wilcox --
  • 2015 ScienceDirect
    editors, Chin-Yi Chen, Xianghe Yan, Charlene R. Jackson.
    1. Introduction to antimicrobial-resistant foodborne pathogens / Patrick Butaye, Maria Angeles Argudín and John Threlfall -- 2. Antimicrobial resistance of Shiga toxin-producing Escherichia coli / Jinru Chen -- 3. Antibiotic resistance in pathogenic Salmonella / Steven C. Ricke and Juliany Rivera Calo -- 4. Antimicrobial resistance and Campylobacter jejuni and C. coli / Mirko Rossi, Satu Olkkola, Mati Roasto, Rauni Kivistö and Marja-Liisa-Hänninen -- 5. Antimicrobial resistance in Yersinia enterocolitica / Anna Fabrega, Clara Ballesté-Delpierre and Jordi Vila -- 6. Antimicrobial resistance in Vibrio species / Craig Baker-Austin -- 7. Antimicrobial resistance in Shigella species / Keith A. Lampel -- 8. Antimicrobial resistance in Listeria spp. / Nathan A. Jarvis, Philip G. Crandall, Corliss A. O'Bryan and Steven C. Ricke -- 9. Antibiotic resistance in Enterococci : a food safety perspective / Anuradha Ghosh and Ludek Zurek -- 10. Clostridium difficile: a food safety concern? / Jane W. Marsh and Lee H. Harrison -- 11. Methods for the detection of antimicrobial resistance and the characterization of Staphylococcus aureus isolates from food-producing animals and food of animal origin / Kristina Kadlec, Sarah Wendlandt, Andrea T. Fessler and Stefan Schwarz -- 12. Non-phenotypic tests to detect and characterize antibiotic resistance mechanisms in Enterobacteriaceae / Agnese Lupo, Krisztina M. Papp-Wallace, Robert A. Bonomo and Andrea Endimiani -- 13. Monitoring and surveillance : the national antimicrobial resistance monitoring system / Emily Crarey, Claudine Kabera and Heather Tate -- 14. Risk assessment of antimicrobial resistance / H. Gregg Claycamp -- 15. Food microbial safety and animal antibiotics / Louis Anthony (Tony) Cox -- 16. Antibiotic-resistant bacteria and resistance genes in the water-food nexus of the agricultural environment / Pei-Ying Hong -- 17. Development and application of novel antimicrobials in food and food processing / Yangjin Jung and Karl R. Matthews -- 18. Database resources dedicated to antimicrobial peptides / Guangshun Wang -- 19. Metabolic network analysis-based identification of antimicrobial drug target in pathogenic bacteria / Vinayak Kapatral -- 20. Application of metagenomic technologies for antimicrobial resistance and food safety research and beyond / Chin-Yi Chen, Xianghe Yan, Siyun Wang and Charlene R. Jackson.
  • 2008 Springer
    I.W. Fong, Karl Drlica, editors.
    Mechanisms of resistance by gram-positive bacteria (streptococci and enterococci) / Javier Aspa Marco ... [et al.] -- Emergence of MRSA in the community / Adam L. Cohen, Rachel Gorwitz, and Daniel B. Jernigan -- Antimicrobial resistance to sexually transmitted infections / Hillard Weinstock, David Trees, and John Papp -- Resistance of gram-negative bacilli to antimicrobials / Patricia A. Bradford and Charles R. Dean -- Mycobacterial antimicrobial resistance / Peter D.O. Davies and Richard Cooke -- Antimicrobial resistance of anaerobic bacteria / Ellie J.C. Goldstein, Diane M. Citron, and David W. Hecht -- Clinical significance and biological basis of HIV drug resistance / Jorge L. Martinez-Cajas, Marco Petrella, and Mark A. Wainberg -- Resistance of herpesviruses to antiviral agents / G. Boivin and W.L. Drew -- Hepatitis virus resistance / Jean-Michel Pawlotsky -- Resistance to antifungal agents / Beth A. Arthington-Skaggs and John H. Rex -- An anti-mutant approach for antimicrobial use / Karl Drlica ... [et al.]
  • 2010 Springer
    Aníbal de J. Sosa, Denis K. Byarugaba, Carlos F. Amábile-Cuevas, Po-Ren Hsueh, Samuel Kariuki, Iruka N. Okeke, editors ; foreword by Thomas F. O'Brien ; introductory preface by the editors ; guest preface by Stuart B. Levy.
    General issues in antimicrobial resistance -- Global perspectives of antibiotic resistance -- Mechanisms of antimicrobial resistance -- Poverty and root causes of resistance in developing countries -- What the future holds for resistance in developing countries -- Introduction of antimicrobial agents in resource-constrained countries: impact on the emergence of resistance -- Human impact of resistance -- Human immunodeficiency virus: resistance to antiretroviral drugs in developing countries -- Drug resistance in malaria in developing countries -- Drug resistance in Mycobacterium tuberculosis -- Antifungal drug resistance in developing countries -- Drug resistance in African trypanosomiasis -- Antimicrobial resistance in enteric pathogens in developing countries -- Bacterial-resistant infections in resource-limited countries -- Prevalence of resistant enterococci in developing countries -- Antimicrobial resistance in gram-negative bacteria from developing countries -- Resistance in reservoirs and human commensals -- Antimicrobial use and misuse -- Determinants of antimicrobial use: poorly understood-poorly researched -- Antimicrobial use and resistance in Africa -- Antimicrobial drug resistance in Asia -- Antimicrobial drug resistance in Latin American and the Caribbean -- Hospital infections by antimicrobial-resistant organisms in developing countries -- Cost, policy, and regulation of antimicrobials -- Economic burden of antimicrobial resistance in the developing world -- Strengthening health systems to improve access to antimicrobials and the containment of resistance -- Role of unregulated sale and dispensing of antimicrobial agents on the development of antimicrobial resistance in developing countries -- Counterfeit and substandard anti-infectives in developing countries -- Strategies to contain antimicrobial resistance -- Containment of antimicrobial resistance in developing countries and lessons learned -- Surveillance of antibiotic resistance in developing countries: needs, constraints and realities -- Vaccines: a cost-effective strategy to contain antimicrobial resistance -- Teaching appropriate antibiotic use in developing countries -- Containing global antibiotic resistance: ethical drug promotion in the developing world -- News media reporting of antimicrobial resistance in Latin America and India.
  • 2014 Springer
    Flavia Marinelli, Olga Genilloud, editors.
    Reports on the emergence and prevalence of resistant bacterial infections in hospitals and communities raise concerns that we may soon no longer be able to rely on antibiotics as a way to control infectious diseases. Effective medical care would require the constant introduction of novel antibiotics to keep up in the "arms race" with resistant pathogens. This book closely examines the latest developments in the field of antibacterial research and development. It starts with an overview of the growing prevalence of resistant Gram-positive and Gram-negative pathogens, including their various resistance mechanisms, prevalence, risk factors and therapeutic options. The focus then shifts to a comprehensive description of all major chemical classes with antibacterial properties, their chemistry, mode of action, and the generation of analogs; information that provides the basis for the design of improved molecules to defeat microbial infections and combat the emerging resistances. In closing, recently developed compounds already in clinical use, those in preclinical or first clinical studies, and a number of promising targets to be exploited in the discovery stage are discussed.
  • 2015 Wiley
    Daniel Lednicer.
    "Antineoplastic Drugs: Organic Syntheses is written to appeal to organic and medicinal chemists in industry and academia. It is beneficial to those composing grant proposals for NCI and related organizations"-- Provided by publisher.
  • 2006 Springer
    edited by Martial G. Bourassa and Jean-Claude Tardif.
  • 2014 Wiley
    [edited by] Hordur G. Kristinsson and Sivakumar Raghavan.
    1. Oxidation in aquatic foods and analysis methods / Magnea G. Karlsdottir, Holly T. Petty, and Hordur G. Kristinsson -- 2. Protein oxidation in aquatic foods / Caroline P. Baron -- 3. Influence of processing on lipids and lipid oxidation in aquatic foods / Sivakumar Raghavan and Hordur G. Kristinsson -- 4. Strategies to minimize lipid oxidation of aquatic food products post harvest / Huynh Nguyen Duy Bao and Toshiaki Ohshima -- 5. Antioxidative strategies to minimize oxidation in formulated food systems containing fish oils and omega-3 fatty acids / Charlotte Jacobsen, Anna Frisenfeldt Horn, Ann-Dorit Moltke Sorensen, K.H. Sabeena Farvin, and Nina Skall Nielsen -- 6. Methods for assessing the antioxidative activity of aquatic food compounds / Holmfridur Sveinsdottir, Patricia Y. Hamaguchi, Hilma Eidsdottir Bakken, and Hordur G. Kristinsson --7. Influence of fish consumption and some of its individual constituents on oxidative stress in cells, animals, and humans / Britt Gabrielsson, Niklas Andersson, and Ingrid Undeland -- 8. Marine antioxidants: polyphenols and carotenoids from algae / Kazuo Miyashita -- 9. Fish protein hydrolysates: production, bioactivities, and applications / Soottawat Benjakul, Suthasinee Yarnpakdee, Theeraphol Senphan, Sigrun M. Halldorsdottir, and Hordur G. Kristinsson -- 10. Antioxidant properties of marine macroalgae / Tao Wang, Rosa Jonsdottir, Gudrun Olafsdottir, and Hordur G. Kristinsson.
  • 2015 Springer
    Pier Luigi Meroni, editor.
    This book, part of the series Rare Diseases of the Immune System, offers comprehensive, up-to-date coverage of the pathophysiology and management of the antiphospholipid syndrome (APS). Immunologic and genetic aspects are discussed and the pathogenic mechanisms responsible for such phenomena as APS-mediated thrombosis and pregnancy loss or complications are explained. The main clinical manifestations and classification criteria are described and diagnostic tools, identified. Close attention is paid to the nature of the involvement of other organs or organ systems in APS, including the nervous, endocrine, hematologic, cardiovascular, and gastrointestinal systems, the kidney, the skin, and the eye. Specific chapters describe the treatment of the different symptoms, the preventive therapies of value in avoiding recurrences, and innovative treatment approaches. The authors are senior experts in the field who are aided by younger fellows, ensuring that the book is also educationally oriented. This handy volume will be a valuable tool for postgraduates in training and professionals wishing to extend their knowledge of this specific syndrome
  • 2012 Springer
    Doruk Erkan, Silvia S. Pierangeli, editors.
    Part 1. History of Antiphospholipid Syndrome -- 1. Overview of the Last 25 Years and 13 International Congresses on Antiphospholipid Antibodies / Eon Nigel Harris and Silvia S. Pierangeli -- Part II. Basic Science Aspects of Antiphospholipid Syndrome -- 2. What is the Oirgin of Antiphospholipid Antibodies? / Rohan Willis, Yehuda Shoenfeld, Silvia S. Pierangeli and Miri Blank -- 3. What is the Genetics of Antiphospholipid Antibodies/Syndrome? / Thomas L. Ortel, Pier Luigi Meroni, Marta E. Alarcón-Riquelme, Maria O. Borghi and Joan T. Merrill -- 4. What is the Mechanism(s) of Antiphospholipid Antibody-Mediated Thrombosis? / Rohan Willis, Ian P. Giles, Pojen P. Chen, Chary López-Pedrera and María José Cuadrado, and Silvia S. Pierangeli -- 5. What is the Mechanism(s) of Antiphospholipid Antibody-Mediated Pregnancy Morbidity? / Vikki M. Abrahams, Maria O. Borghi, Pier Luigi Meroni, Jacob H. Rand, Elena Raschi, Jane E. Salmon, Francesco Tedesco, and Angela Tincani -- 6. What are the Target Cells and Receptors that are Recognized by Antiphospholipid Antibodies? / Philip G. de Groot, Elena Raschi, Keith R. McCrae, Silvia S. Pierangeli, Panayiotis G. Vlachoyiannopoulos, and Rolf T. Urbanus -- Part 3. 13th Iinternational Congress on Antiphospholid Antibodies Task Force Reports -- 7. Task Force Report on "Criteria" Antiphospholipid Antibody Tests / Robert A. S. Roubey and Silvia S. Pierangeli -- 8. Task Force Report on "Non-criteria" Antiphospholipid Antibody Tests / Maria Laura Bertolaccini, Olga Amengual, Tatsuya Atsumi, Walter L. Binder, William H. Kutteh, Bas de Laat, [and others] -- 9. Task Force Report on Obstetric Antiphospholipid Syndrome / D. Ware Branch, Benjamin Leader and Carl A. Laskin -- 10. Task Force Report on Brain Involvement in Antiphospholipid Syndrome / Joab Chapman, Eyal Muscal and Robin L. Brey -- 11. Task Force Report on the Management of Thrombosis in Antiphospholipid Syndrome / Guillermo Ruiz-Irastorza, Vittorio Pengo, Maria G. Tektonidou, Ioana Ruiz-Arruza, María José Cuadrado, and Munther A. Khamashta -- 12. Task Force Report on Catastrophic Antiphospholipid Syndrome / Gerard Espinosa, Horacio Berman, Doruk Erkan and Ricard Cervera -- 13. Task Force Report on Non-criteria Manifestations: Thrombocytopenia / Gabriela Hernández-Molina, Xavier López-Karpovitch, Emilio B. González and Antonio R. Cabral -- 14. Task Force Report on Non-criteria Manifestations: Nephropathy / Maria G. Tektonidou, Horacio E. Adrogué and Smita Vaidya -- 15. Task Force Report on Non-criteria Manifestations: Cardiac Valve Disease / Gerard Espinosa, Lucía Fernández de Orueta, Elena Lluch, María Ángeles Polvorosa, Sandra Soro, and Ricard Cervera -- 16. Task Force Report on Non-criteria Manifestations: Skin / Michal Solomon, Yehuda Shoenfeld and Gisele Zandman-Goddard -- 17. Task Force Report on Antiphospholipid Syndrome Clinical Research / Doruk Erkan, Silvia S. Pierangeli and Michael D. Lockshin -- Part 4. Future of Antiphospholipid Syndrome -- 18. What are the Potential Future Treatments in Antiphospholipid Syndrome? / Doruk Erkan, Anisur Rahman, Hannah Cohen, Samuel J. Machin and Silvia S. Pierangeli -- 19. Remembrances of Predictions Past / Michael D. Lockshin -- Part 5. Antiphospholipid Syndrome for Patients -- 20. What Should Patients Know about Antiphospholipid Antibodies and Antiphospholipid Syndrome? / Doruk Erkan, Lindsay Lally and Michael D. Lockshin.
  • 2010 Springer
    Marie Laura Bertolaccini, Oier Ateka-Barrutia, and Munther A. Khamashta.
    History / Maria Laura Bertolaccini, Oier Ateka-Barrutia and Munther A. Khamashta -- Epidemiology / Maria Laura Bertolaccini, Oier Ateka-Barrutia and Munther A. Khamashta -- Antiphospholipid Antibodies / Maria Laura Bertolaccini, Oier Ateka-Barrutia and Munther A. Khamashta -- Classification Criteria for APS / Maria Laura Bertolaccini, Oier Ateka-Barrutia and Munther A. Khamashta -- Mortality, Morbidity, and Damage Associated with aPL / Maria Laura Bertolaccini, Oier Ateka-Barrutia and Munther A. Khamashta -- Differences Between Primary and Secondary APS / Maria Laura Bertolaccini, Oier Ateka-Barrutia and Munther A. Khamashta -- Clinical Features / Maria Laura Bertolaccini, Oier Ateka-Barrutia and Munther A. Khamashta -- aPL and Transplantation / Maria Laura Bertolaccini, Oier Ateka-Barrutia and Munther A. Khamashta -- Differential Diagnosis / Maria Laura Bertolaccini, Oier Ateka-Barrutia and Munther A. Khamashta -- Management of APS / Maria Laura Bertolaccini, Oier Ateka-Barrutia and Munther A. Khamashta.
  • 2009 ScienceDirect
    edited by Ricard Cervera, Joan Carles Reverter, Munther Khamashta.
  • 2012 Springer
    Paolo Gresele, Gustav V. R Born, Carlo Patrono, Clive P. Page, editors.
    Part 1. Pathophysiology. Platelets: Production, Morphology and Ultrastructure / Jonathan N. Thon and Joseph E. Italiano -- Platelet Receptors / Alexandre Kauskot and Marc F. Hoylaerts -- Platelet Signaling / Timothy J. Stalker, Debra K. Newman, Peisong Ma, Kenneth M. Wannemacher and Lawrence F. Brass -- Platelet Interaction with the Vessel Wall / Philip G. de Groot, Rolf T. Urbanus and Mark Roest -- Platelets in Atherosclerosis and Thrombosis / Christian Schulz and Steffen Massberg -- Part 2. Pharmacology. Aspirin and Other COX-1 Inhibitors / Carlo Patrono and Bianca Rocca -- Thienopyridines and Other ADP-Receptor Antagonists / Isabell Bernlochner and Dirk Sibbing -- Glycoprotein IIb/IIIa Antagonists / Karen M. Hook and Joel S. Bennett -- Targeting Phosphodiesterases in Anti-platelet Therapy / Matthew T. Rondina and Andrew S. Weyrich -- PAR-1 Inhibitors: A Novel Class of Antiplatelet Agents for the Treatment of Patients with Atherothrombosis / Sergio Leonardi and Richard C. Becker -- Thromboxane Receptors Antagonists and/or Synthase Inhibitors / Giovanni Davì, Francesca Santilli and Natale Vazzana -- Inhibitors of the Interaction Between von Willebrand Factor and Platelet GPIb/IX/V / Paolo Gresele and Stefania Momi -- Inhibitors of the Interactions Between Collagen and Its Receptors on Platelets / Hans Deckmyn, Simon F. De Meyer, Katleen Broos and Karen Vanhoorelbeke -- Intracellular Signaling as a Potential Target for Antiplatelet Therapy / Patrick Andre -- Novel Targets for Platelet Inhibition / Kathleen Freson and Chris Van Geet -- Variability of Platelet Indices and Function: Acquired and Genetic Factors / Giovanni de Gaetano, Iolanda Santimone, Francesco Gianfagna, Licia Iacoviello and Chiara Cerletti -- Small RNAs as Potential Platelet Therapeutics / Leonard C. Edelstein and Paul F. Bray -- Pharmacological Modulation of the Inflammatory Actions of Platelets / Richard Amison, Clive Page and Simon Pitchford -- Part 3. Therapy. The Role of Laboratory Monitoring in Antiplatelet Therapy / Marco Cattaneo -- Antiplatelet Agents in Ischemic Heart Disease / Christopher H. May and A. Michael Lincoff -- Antiplatelet Therapy in Cerebrovascular Disorders / Ralph Weber, Johannes Brenck and Hans-Christoph Diener -- Antiplatelet Therapy in Peripheral Artery Disease / Francesco Violi, Stefania Basili, Jeffrey S. Berger and William R. Hiatt -- Primary Prevention of Ischaemic Cardiovascular Disorders with Antiplatelet Agents / Tom Mead.
  • 2013 Springer
    Albert Ferro, David A. Garcia, editors.
    Antiplatelet Agents: Current and Novel -- Antiplatelet Drug Resistance and Variability in Response: The Role of Antiplatelet Therapy Monitoring -- Anticoagulant Drugs: Current and Novel -- Antithrombotic Treatment of Cardiovascular Disease -- Approaches to the Prophylaxis and Treatment of Venous and Cardiac Thromboembolic Disease.
  • 2008 HighWire
    edited by Josef-Franz Neumann.
  • 2007 HighWire
    edited by Christoph Bode.
  • 2012 Karger
    volume editors, Victor L. Serebruany, Dan Atar.
  • 2014 Wiley
    edited by Ron Waksman, Paul A. Gurbel, Michael A. Gaglia, Jr.
  • 2015 Springer
    Lee L. Swanstrom, Christy M. Dunst, editors.
    This volume provides a comprehensive, state-of-the-art overview of the major issues specific to the field of antireflux surgery. It provides exceptional instructional detail regarding performance of antireflux surgery from leading esophageal surgeons around the world. This volume represents the only resource of its kind dedicated specifically to the issues unique to antireflux surgery. It is rich in detail and helpful illustrations that instruct surgeons in proper technique as well as presenting the reasoning behind various techniques. Written by experts in the field, Antireflux Surgery is of great value to practicing surgeons who perform gastrointestinal surgery, medical students, surgical residents, and fellows.
  • 2006 NCBI Bookshelf
    edited by Dr. Maria Geretti.
  • 2008 CRCnetBASE
    edited by Stanley T. Crooke.
    Mechanisms of antisense drug action, an introduction / Stanley T. Crooke ... [et al.] -- The RNase H mechanism / Walt Lima, Hongjiang Wu, and Stanley T. Crooke -- Small RNA silencing pathways / Alla Sigova and Phillip D. Zamore -- Splice switching oligonucleotides as potential therapeutics / Peter Sazani, Maria A. Graziewicz, and Ryszard Kole -- Basic principles of antisense drug discovery / Susan M. Freier and Andrew T. Watt -- The medicinal chemistry of oligonucleotides / Eric E. Swayze and Balkrishen Bhat -- Basic principles of the pharmacokinetics of antisense oligonucleotide drugs / Arthur A. Levin, Rosie Z. Yu, and Richard S. Geary -- Routes and formulations for delivery of antisense oligonucleotides / Gregory E. Hardee, Lloyd G. Tillman, and Richard S. Geary -- Liposomal formulations for nucleic acid delivery / Ian MacLachlan -- Pharmacological properties of 2'-O-methoxyethyl-modified oligonucleotides / C. Frank Bennett -- Pharmacokinetic/pharmacodynamic properties of phosphorothioate 2'-O-(2-methoxyethyl)-modified antisense oligonucleotides in animals and man / Richard S. Geary ... [et al.] -- Toxicologic properties of 2'-O-methoxyethyl chimeric antisense inhibitors in animals and man / Scott P. Henry ... [et al.] -- An overview of the clinical safety experience of first- and second-generation antisense oligonucleotides / T. Jesse Kwoh -- Manufacturing and analytical processes for 2'-O-(2-methoxyethyl)-modified oligonucleotides / Daniel C. Capaldi and Anthony N. Scozzari -- Utilizing chemistry to harness RNA interference pathways for therapeutics : chemically modified siRNAs and antagomirs / Muthiah Manoharan and Kallanthottathil G. Rajeev. Discovery and development of RNAi therapeutics / Antonin R. deFougerolles and John M. Maraganore -- Optimization of second-generation antisense drugs: going beyond generation 2.0 / Brett P. Monia ... [et al.] -- Modulating gene function with peptide nucleic acids (PNA) / Peter E. Nielsen -- Locked nucleic acid / Troels Koch and Henrik Ørum -- Morpholinos / Patrick L. Iversen -- Potential therapeutic applications of antisense oligonucleotides in ophthalmology / Lisa R. Grillone and Scott P. Henry -- Cardiovascular therapeutic applications / Rosanne M. Crooke, Brenda Baker, and Mark Wedel -- Developing antisense drugs for metabolic diseases: a novel therapeutic approach / Sanjay Bhanot -- Inflammatory diseases / Susan A. Gregory and James G. Karras -- Antisense oligonucleotides for the treatment of cancer / Boris A. Hadaschik and Martin E. Gleave -- Targeting neurological disorders with antisense oligonucleotides / Richard A. Smith and Timothy M. Miller -- Mechanisms and therapeutic applications of immune modulatory oligodeoxynucleotide and oligoribonucleotide ligands for toll-like receptors / Jörg Vollmer and Arthur M. Krieg -- Aptamer opportunities and challenges / Charles Wilson.
  • 2012
    Nam Keun Kim.
    Of the two pathways through which we hear, air conduction (AC) and bone conduction (BC), the fundamental mechanisms of the BC pathway remains to be poorly understood, despite its clinical significance. In the first study, a finite-element (FE) model of a human middle ear and cochlea was developed to gain insight into the mechanisms of BC hearing. BC excitations were simulated in the form of rigid-body vibrations of the surrounding bony structures in the x, y, and z orthogonal directions. The results show that the BM vibration characteristics are essentially invariant regardless of whether the excitation is BC, independent of excitation directions, or for AC. Analysis reveals that this is because the BM vibration apparently responds only to the anti-symmetric slow wave cochlea fluid pressure component and not the symmetric fast wave pressure component. In the second study, an improved three-dimensional FE model of a human middle ear coupled to a cochlea was formulated. The geometry of both the middle ear and cochlea, including semicircular canals, was obtained from micro-computed tomography ([mu]CT) images. In the study, BC and AC excitations were simulated as the same way as the previous simulation in the first study. After testing a range of vibrational directions, it was found that the vibrational direction normal to the BM surface at the base of the cochlea caused the highest BM velocity response across all tested frequencies--higher even than an excitation direction normal to the BM surface at the (non-basal) best-frequency locations corresponding to the other stimulus frequencies. The basal part of the human cochlea features a well-developed hook region, in which the BM undergoes a sudden curvature that produces the largest difference in fluid volume between the scala vestibuli (SV) and scala tympani (ST) found throughout the whole cochlea, and due to the sudden curvature of the hook region, the normal direction to the BM surface in this region differs significantly from the normal directions to the BM along the rest of the length of the cochlea. In the third study, the effects of otosclerosis and superior semicircular canal (SSC) dehiscence (SSCD) on hearing sensitivity were investigated via AC and BC pathways, using the FE model developed in the second study. Otosclerosis conditions were simulated by stiffing stapes annular ligament and removing the middle-ear inertia through removing stapedius tendon and incudostapedial joint. Dehiscences were modeled by removing a section of the outer bony wall of the SSC and applying a zero-pressure condition to the fluid surface thus exposed. In the results, otosclerosis condition caused the biggest bone-conduction hearing loss around 1.5 kHz, which is called 'Carhart notch'. In addition, dehiscence caused decreasing of the basilar membrane velocity, VBM(x), and fluid pressure in the cochlea in air conduction whereas increasing in bone conduction at low frequencies. Furthermore, the location and size of dehiscence affected the BC hearing threshold. Not previously shown is that the initial width (defined as the edge of dehiscence at which the flowing energy from the oval window meets for the first time) on the vestibular side of the dehiscence has more effect than the area of the dehiscence. The analyses of the FE model further predict that the ABG due to a dehiscence should converge to 0 dB at 10 kHz.
  • edited by Roy J. Vaz and Thomas Klabunde.
  • 2010 Springer
    edited by Arman T. Askari, A. Michael Lincoff.
    Platelets in arterial thrombosis -- Role of coagulation in arterial and venous thrombosis -- Link between inflammation and thrombosis -- Genetics of thrombosis -- Aspirin in primary and secondary prevention of cardiovascular disease -- Thienopyridines in stable coronary disease -- Antiplatelet therapies in unstable angina and non-ST segment elevation myocardial infarction -- Unfractionated heparin and enoxaparin for the management of non-ST-segment elevation acute coronary syndromes -- Direct thrombin inhibitors in acute coronary syndromes -- Synthetic factors Xa inhibition in acute coronary syndromes -- Antiplatelet therapies: aspirin, clopidogrel and thienopyridines, and glycoprotein IIb/IIIa inhibitors for the management of ST-segment elevation myocardial infarction -- Antithrombin therapy for acute ST-segment elevation myocardial infarction -- Fibrinolysis and facilitated PCI -- Antithrombotic therapy in percutaneous coronary intervention -- Antithrombotic therapy in carotid and peripheral intervention -- Monitoring of antithrombotic therapies in interventional cardiology -- Venous thromboembolism -- Fibrinolysis for pulmonary embolism -- Duration of anticoagulant therapy after venous thromboembolism -- Antithrombotic therapy for atrial fibrillation and cardioversion -- Antithrombotic therapy for valvular heart disease -- Antithrombotic therapy in heart failure and cardiomyopathy -- Heparin-induced thrombocytopenia -- Resistance to antiplatelet drugs.
  • 2011 Karger
    volume editors, Peter R. Donald, Paul D. van Helden.
    History of drug discovery : early evaluation studies and lessons learnt from them / Ahmad, Z., Makaya, N.H. and Grosset, J. -- Tuberculosis treatment trials past and present : old and new challenges / Nunn, N. -- The rifamycins : renewed interest in an old drug class / Burman, W., Dooley, K.E., and Nuermberger, E. -- Isoniazid pharmacokinetics and efficacy in adults and children / Donald, P.R. and Schaaf, H.S. -- Recent developments in the study of pyrazinamide : an update / Mitchison, D.A. and Zhang, Y. -- Experience with phase III clinical trials of antituberculosis drugs and regimens : conclusions and lessons for the future / Jindani, A. -- Tuberculosis recurrence : exogenous or endogenous? / Williams, M. ... [et al.] -- Second-line antituberculosis drugs : current knowledge, recent research findings and controversies / Schaaf, H.S., Seddon, J.A., and Caminero, J.A. -- Acquisition, transmission, and amplification of drug-resistant tuberculosis / Müller, B. ... [et al.] -- The treatment of tuberculosis in children -- Cruz, A.T. and Starke, J.R. -- Issues and challenges in the development of novel tuberculosis drug regimens / Erondu, N. and Ginsberg, A. -- Drug resistance in mycobacterium tuberculosis : molecular mechanisms and laboratory susceptibility testing / Bittger, E.C. -- The role of the mouse model in the evaluation of new antituberculosis drugs / Nuermberger, E.L. -- Current issues in tuberculosis pharmacokinetics / Egelund, E.F. and Peloquin, C.A. -- Pharmacological considerations of antitubercular agents in children / Goldman, J.L., Kearns, G.L., and Abdel-Rahman, S.M. -- Interactions between antituberculosis and antiretroviral agents / Mcilleron, H. and Khoo, S.H. -- Diabetes mellitus and tuberculosis treatment / Ruslami, R., Van Crevel, R. -- Early bactericidal activity of antituberculosis agents / Maritz, J.Z., Diacon, A.H., and Donald, P.R. -- Assessment of whole-blood bactericidal activity in the evaluation of new antituberculosis drugs / Wallis, R.S. -- Serial sputum colony counting in drug regimens / Sloan, D. and Davies, G. -- The evaluation of new antituberculosis drugs in children / Mcneeley, D.F. ... [et al.] -- A new era in tuberculosis treatment : what does the future hold? / Duncan, K.
  • 2008 WHO
    [written by Abigail Wright, Matteo Zignol].
    Also available: Print – 2008
  • 2015 Karger
    volume editors, Gerhard Rogler, Toshifumi Hibi, Hans Herfarth, Ole Haagen Nielsen.
  • 2013 Springer
    Evandro Fei Fang, Tzi Bun Ng, editors.
    The modern unhealthy diet and lifestyle in conjunction with pathogens, environmental carcinogens and multiple other risk factors increase humans' susceptibility to different diseases exemplified by elevated levels of cancers, cardiovascular and communicable diseases. Screening of potential drugs from medicinal plants and animals provides a promising strategy for the alleviation of the impact of these diseases. Components with potential medicinal applications include RIPs, RNases, lectins, protease inhibitors and numerous small compounds. These compounds have shown both preventive and therapeutic effects for humans. This book is a compilation of articles written by internationally renowned experts exploring the different uses of medicinal compounds in human therapeutics. Here we provide a comprehensive outlook on both qualitative and quantitative studies focusing on medicinal plants and animals, and establishing a link between laboratory research discovery and clinical applications.
  • 2010 Karger
    volume editors, F. Bandello, M. Battaglia Parodi ; co-editors, A.J. Augustin, P. Iacono, R.O. Schlingemann, U. Schmidt-Erfurth,F.D. Verbraak.
    Angiostatic and angiogenic factors / De Groot, H. ... [et al.] -- Mechanisms of ocular angiogenesis and its molecular mediators / Siemerink, M.J., Augustin, A.J., Schlingemann, R.O. -- Antivascular endothelial growth factors in age-related macular degeneration / Schmidt-Erfurth, U. ... [et al.] -- Antivascular endothelial growth factor in diabetic retinopathy / Iacono, P., Parodi, M.B., Bandello, F. -- Retinal vein occlusions / Buehl, W., Sacu, S., Schmidt-Erfurth, U. --; Antivascular endothelial growth factor for choroidal neovascularization in pathologic myopia / Parodi, M.B., Iacono, P., Bandello, F. -- Antivascular endothelial growth factors for inflammatory chorioretinal disorders / Parodi, M.B. ... [et al.] -- Antivascular endothelial growth factor treatment in pseudoxanthoma elasticum patients / Verbraak, F.D. -- Antivascular endothelial growth factor in hereditary dystrophies / Parodi, M.B., Iacono, P., Bandello, F. -- Antivascular endothelial growth factor as an approach for macular edema / Buchholz, P., Buchholz, A., Augustin, A.J. -- Angiogenesis and vascular endothelial growth factors in intraocular tumors / Missotten, G.S., Jager, M.J., Schlingemann, R.O. -- Antivascular endothelial growth factors in anterior segment diseases / Scholl, S., Kirchhof, J., Augustin, A.J.
  • 2013 Springer Protocols
    edited by Edwin Yunhao Gong.
    Part I Human immunodeficiency virus type 1 (HIV-1) -- Fluorescence-based high-throughput screening assay to identify HIV-1 inhibitors / Peggy Geluykens ... [et al.] -- Homogeneous time-resolved fluorescence assay to identify inhibitors of HIV-1 fusion / Liesbet Smeulders ... [et al.] -- Identification of HIV-1 reverse transcriptase inhibitors using a scintillation proximity assay / Bertrand Van Schoubroeck ... [et al.] -- Biochemical screening assays to identify HIV-1 integrase inhibitors / Marleen Clynhens ... [et al.] -- HIV-1 genotyping of the protease-reverse transcriptase and integrase genes to detect mutations that confer antiretroviral resistance / Peter Van den Eede ... [et al.] -- Part II Hepatitis viruses -- In vitro kinetic profiling of hepatitis C virus NS3 protease inhibitors by progress curve analysis / Rumin Zhang and William T. Windsor -- Novel hepatitis C virus NS5B polymerase assay of de novo initiated RNA synthesis directed from a heteropolymeric RNA template / Eric Ferrari and Hsueh-Cheng Huang -- Selecting and characterizing drug-resistant hepatitis C virus replicon / Inge Vliegen, Leen Delang, and Johan Neyts -- Cellular replicon-based phenotyping assay to determine susceptibility of hepatitis C virus clinical isolates to NS3/4A protease inhibitors / Leen Vijgen ... [et al.] -- Expression and purification of hepatitis C virus protease from clinical samples / Liesbet van der Helm -- Surface plasmon resonance as a tool to select potent drug candidates for hepatitis C virus NS5B polymerase / Erna Cleiren, Benoit Devogelaere, and Katleen Fierens -- Amplification and sequencing of the hepatitis C virus NS3/4A protease and the NS5B polymerase regions for genotypic resistance detection of clinical isolates of subtypes 1a and 1b / Diana Koletzki ... [et al.] -- Southern blot assay for detection of hepatitis B virus covalently closed circular DNA from cell cultures / Dawei Cai ... [et al.] -- In vitro phenotyping of recombinant hepatitis B virus containing the polymerase/reverse transcriptase gene from clinical isolates / Yang Liu and Kathryn M. Kitrinos -- Part III Flaviviruses -- Cell-based antiviral assays for screening and profiling inhibitors against dengue virus / Edwin Yunhao Gong ... [et al.] -- Duplex real-time RT-PCR assay for profiling inhibitors of four dengue serotypes / Edwin Yunhao Gong ... [et al.] -- High-throughput screening using dengue virus reporter genomes / Wolfgang Fischl and Ralf Bartenschlager -- Fluorimetric and HPLC-based dengue virus protease assays using a FRET substrate / Christoph Nitsche and Christian D. Klein -- Expression and purification of dengue virus NS5 polymerase and development of a high-throughput enzymatic assay for screening inhibitors of dengue polymerase / Edwin Yunhao Gong ... [et al.] -- Detection and quantification of flavivirus NS5 methyl- transferase activities / Siew Pheng Lim, Christophe Bodenreider, and Pei-Yong Shi -- Testing antiviral compounds in a dengue mouse model / Wouter Schul, Andy Yip, and Pei-Yong Shi -- Construction of self-replicating subgenomic west nile virus replicons for screening antiviral compounds / Sofia L. Alcaraz-Estrada, Erin Donohue Reichert, and Radhakrishnan Padmanabhan -- Part IV Herpes viruses -- Methods for screening and profiling inhibitors of herpes simplex viruses / Edwin Yunhao Gong -- In vivo evaluation of antiviral efficacy against genital herpes using mouse and guinea pig models / Frances Valencia, Ronald L. Veselenak, and Nigel Bourne -- Fluorescence-based high-throughput screening assay for identifying human cytomegalovirus inhibitors / Christel Van den Eynde ... [et al.] -- Part V Respiratory viruses -- Fluorescence-based high-throughput antiviral compound screening assay against respiratory syncytial virus / Leen Kwanten, Ben De Clerck, and Dirk Roymans -- Screening and evaluation of anti-respiratory syncytial virus compounds in cultured cells / Anna Lundin, Tomas Bergström, and Edward Trybala -- Evaluation of antiviral efficacy against human respiratory syncytial virus using cotton rat and mouse models / Joke Van den Berg, Leen Kwanten, and Dirk Roymans -- In vivo evaluation of antiviral compounds on respiratory syncytial virus using a juvenile vervet monkey (Chlorocebus pygerythrus) infection model / Lieselot Houspie ... [et al.] -- Methods to determine mechanism of action of anti-influenza inhibitors / Angela Luttick, Stephanie Hamilton, and Simon P. Tucker -- Methods for evaluation of antiviral efficacy against influenza virus infections in animal models / Donald F. Smee and Dale L. Barnard -- Part VI Alphaviruses -- Development of a high-throughput antiviral assay for screening inhibitors of chikungunya virus and generation of drug-resistant mutations in cultured cell / Edwin Yunhao Gong ... [et al.] -- Mouse model of chikungunya virus with utility in antiviral studies / Ashley Dagley and Justin G. Julander.
  • 2012 Springer Protocols
    edited by John M. Watson and Ming-Bo Wang.
    Historical overview of RNAi in plants / John A. Lindbo -- RNA silencing and antiviral defense in plants / Claire Agius [and others] -- Biological chemistry of virus-encoded suppressors of RNA silencing : an overview / Rustem T. Omarov and Herman B. Scholthof -- Virus-induced gene silencing using begomovirus satellite molecules / Xueping Zhou and Changjun Huang -- Strategies for viral cross protection in plants / Changyong Zhou and Yan Zhou -- Tobacco rattle virus (TRV)-based virus-induced gene Silencing / Shawn Bachan and Savithramma P. Dinesh-Kumar -- Virus-induced gene silencing in hexaploid wheat using barley stripe mosaic virus vectors / Steven R. Scofield and Amanda S. Brandt -- Characterization of plant virus-encoded gene silencing suppressors / Hajime Yaegashi, Masamichi Isogai, and Nobuyuki Yoshikawa -- Generation of plant small RNA cDNA libraries for high-throughput sequencing / Qian-Hao Zhu and Christopher A. Helliwell -- Modeling antiviral resistance in plants / Robert S. Anderssen and Peter M. Waterhouse -- Isolation and detection of small RNAs from plant tissues / Neil A. Smith and Andrew L. Eamens -- Isolation and analysis of small RNAs from virus-infected plants / Shaun J. Curtin [and others] -- Use of hairpin RNA constructs for engineering plant virus resistance / Neena Mitter and Ralf G. Dietzgen -- Artificial microRNAs for plant virus resistance / Jing Qu, Jian Ye, and Rongxiang Fang -- Isolation and biochemical analysis of plant small RNAs / H. Alexander Ebhardt, Mariana Oviedo Ovando, and Peter J. Unrau -- Isolation and analysis of plant RNA-dependent RNA polymerases / Julien Curaba -- Plant viroids : isolation, characterization/detection, and analysis / Robert A. Owens, Teruo Sano, and Nuria Duran-Vila -- Structural and functional analysis of CMV satellite RNAs in RNA silencing / Hanako Shimura and Chikara Masuta -- Virus-Induced Gene Silencing in Soybean / Aardra Kachroo and Said Ghabrial -- Chimeric, infectious, and stable virus transcripts to study RNA silencing in "Dark Green" Islands / Robin M. MacDiarmid -- Rolling circle amplification-mediated long hairpin RNA library construction in plants / Lei Wang and Yun-Liu Fan -- Interaction between plant viroid-induced symptoms and RNA silencing / Vicente Pallas, German Martinez, and Gustavo Gomez -- Identification of small molecule inhibitors of tomato bushy stunt virus replication / Zsuzsanna Sasvari and Peter D. Nagy -- Expression of dominant-negative mutants to study host factors affecting plant virus infections / Daniel Barajas and Peter D. Nagy.
  • 2011 Springer Protocols
    edited by Ronald P. van Rij.
    [Publisher-supplied data] Viruses and RNAi share an intricate relationship at many levels. RNAi is an important antiviral defense mechanism in plants and invertebrates, microRNAs of viral or cellular origin affect many aspects of virus biology, and replication of many, if not all, mammalian viruses can be suppressed by RNAi. Antiviral RNAi: Concepts, Methods, and Applications provides a collection of protocols for the analysis of viral small RNAs and natural antiviral RNAi responses as well as for the development and optimization of RNAi-based antiviral drugs. As RNAi is a central regulatory mechanism in the cell, the methods in this volume can also be applied out of the context of a virus infection. Divided into five convenient parts, this detailed volume reviews important basic concepts in the field of antiviral RNAi, provides experimental and bio-informatic tools for the analysis of small silencing RNAs, covers methods to biochemically dissect RNAi-based antiviral defense and viral counter-defense mechanisms, describes methods for the design, expression, and delivery of therapeutic antiviral siRNAs, and finally presents genome-wide RNAi approaches for the identification of factors involved in virus replication. Written in the highly successful Methods in Molecular Biology series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Antiviral RNAi: Concepts, Methods, and Applications serves as an ideal guide for both novice and experienced researchers alike striving to dissect the role of RNAi in the viral life cycle or to further boost the development of novel therapeutics and experimental tools based on RNAi technology.
  • 2009 Springer
    contributors, J. Anderson ... [et al.] ; Hans-Georg Kräusslich, Ralf Bartenschlager, editors.
  • 2014 Springer
    edited by Richard Cohen and Alastair Windsor.
    Anus: Treatment and Pathology is the perfect guide for the diagnosis and management of patients with anal canal and pelvic floor disorders. Using annotated diagrams matched to cross-sectional radiology with ultrasound and MRI, this book will not only give the reader a thorough understanding of normal anal canal and pelvic floor anatomy, but will also take the reader through the common benign and malignant conditions which affect the anal canal and pelvis describing in detail their pathophysiology, investigation and management. Anus: Treatment and Pathology is aimed at practicing general surgeons, colorectal surgeons and surgical trainees, which can be used either as a practical reference guide for day to day colorectal surgical practice or for in depth text based learning.
  • 2013
    Allan V. Horwitz.
    Status: Not Checked OutLane Catalog Record
    Allan V. Horwitz, a sociologist of mental illness and mental health, narrates how this condition has been experienced, understood, and treated through the ages - from Hippocrates, through Freud, to today.
  • 2008 Springer
    Sherry H. Stewart, Patricia J. Conrod editors.
    Theoretical issues -- Epidemiological perspectives on co-occurring anxiety disorder and substance use disorder -- The neurobiology of anxiety: potential for co-morbidity of anxiety and substance use disorders -- Research findings -- Posttraumatic stress disorder and substance use disorder: neuroimaging, neuroendocrine, and psychophysiological findings -- Co-morbidity of social phobia and alcohol use disorders: a review of psychopathology research findings -- Panic spectrum disorders and substance use -- Treatment strategies -- Treatment of co-morbid obsessive-compulsive disorder and substance use disorders -- Treatment for co-morbid posttraumatic stress disorder and substance use disorders -- Treatment of co-occurring alcoholism and social anxiety disorder -- Treating co-morbid panic disorder and substance use disorder -- Cognitive- behavioral treatment of co-morbid panic psychopathology and tobacco use and dependence -- Personality-based approaches to treatment of co-morbid anxiety and substance use disorder -- Medical management of co-morbid anxiety and substance use disorder -- Integration and conclusions -- Anxiety disorder and substance use disorder co-morbidity: common themes and future directions.
  • 2013 Karger
    volume editors, D.S. Baldwin, B.E. Leonard.
    Preface : concerted efforts to improve the understanding and treatment of anxiety disorders / J. Angst, D.S. Baldwin -- On the nature of obsessions and compulsions / S. de Haan, E. Rietveld, D. Denys -- The origin of anxiety disorders : an evolutionary approach / L.E.W.G. Willers, N.C. Vulink, D. Denys, D.J. Stein -- Genetic factors in anxiety disorders / K. Domschke, E. Maron -- Neuroimaging in anxiety disorders / M. Fredrikson, V. Faria -- Potential neuroimmunological targets in the treatment of anxiety disorders / R. Hou, Z. Tang, D.S. Baldwin -- Anxiety and cardiovascular disease / S.J.C. Davies, C. Allgulander -- The early phases of anxiety disorders : from prevention to treatment / J. Vázquez-Bourgon, A. Herrán, J.L. Vázquez-Barquero -- Duration of untreated Illness and duration of illness in anxiety disorders : assessment and influence on outcome / A.C. Altamura, G. Camuri, B. Dell'Osso -- Pharmacotherapy of generalized anxiety disorder / C. Allgulander, D.S. Baldwin -- Pharmacological treatment of panic disorder / B. Bandelow, D.S. Baldwin, P. Zwanzger -- Pharmacological treatment of social anxiety disorder / V.G. Masdrakis, D. Turic, D.S. Baldwin -- Pharmacotherapy of posttraumatic stress disorder / A. Koller, D.J. Stein -- Evidence-based treatment pathways for translational studies in obsessive-compulsive disorders / N.A. Fineberg, S. Pallanti, S. Reghunandanan.
  • 2008 Springer
    John R. Vanin and James D. Helsley ; foreword by David M. Morgan.
  • 2015 Springer
    Dan J. Stein, Bavi Vythilingum, editors.
    Foreword by Donna Stewart (Toronto) and Helen Herman (Australia) -- Introduction -- Generalised Anxiety Disorder -- Panic Disorder -- Social Anxiety Disorder -- Obsessive-compulsive and Related Disorders -- Trauma and Stressor-Related Disorders -- Anxiety disorders during pregnancy and lactation -- Anxiety and related disorders in women -- Anxiety and related disorders in men.
  • 2008 Springer
    Michael J. Zvolensky, Jasper A.J. Smits [editors].
    Health behaviors and anxiety disorders -- Tobacco use and panic psychopathology: current status and future directions -- Alcohol use and anxiety disorders -- Illicit drug use across the anxiety disorders: prevalence, underlying mechanisms, and treatment -- The promise of exercise interventions for the anxiety disorders -- Anxiety and insomnia: theoretical relationship and future research -- Physical conditions and anxiety disorders -- Anxiety disorders and physical illness comorbidity: an overview -- The relation between puberty and adolescent anxiety: theory and evidence -- Anxiety, anxiety disorders, and the menstrual cycle -- Pain and anxiety disorders -- Asthma in anxiety and its disorders: overview and synthesis -- Cardiovascular disease and anxiety -- HIV and anxiety -- Physical illness and treatment of anxiety disorders: a review.
  • 2006
    Brian J. Zink.
    Status: Not Checked OutLane Catalog Record
  • 2006
    [edited by] Michael Wagner, Robert Frigg.
    Status: Not Checked OutLane Catalog Record
  • 2015- HighWire
  • 2009 Springer
    edited by Gilbert R. Upchurch Jr., Enrique Criado ; foreword by Raman Berguer.
  • 2009 ClinicalKey
    Stuart J. Hutchison.
    Aortic physiology and function: anatomic and histologic considerations -- Anatomic variants of the aorta -- Examination and imaging of the aorta -- Acute aortic dissection -- Aortic intramural hematoma -- Late complications of aortic dissection -- Aortic complications of catheterization, surgery, and instrumentation -- Aortic atheromatous disease: plaques, debris, and obstruction -- Aortic atheromatous disease: thrombosis, thromboembolism, and atheroembolism -- Aortic atheromatous disease: ulcers and penetrating aortic ulcers -- Thoracic aortic aneurysms -- Abdominal aortic aneurysms -- Endovascular therapy for thoracic aortic pathology -- Diseases of the aortic root -- Congenital bicuspid aortic valve-associated aortopathy -- Coarctation and atresia of the aorta -- Marfan syndrome -- Traumatic disruption of the aorta -- Tumors of the aorta -- Infectious and mycotic aneurysms -- Noninfectious aortitis: Takayasu's disease -- Noninfectious aortitis: giant cell aortitis, SLE, and other aortitides.
  • 2007 Springer
    edited by Ragavendra R. Baliga ... [et al.].
  • 2010 Springer
    C.A. Yankah, Y. Weng, R. Hetzer, eds.
  • 2015 Springer
    Amr E. Abbas, editor.
    1. General considerations and etiologies of aortic stenosis -- 2. Clinical assessment of the severity of aortic stenosis -- 3. Physiological basis for area and gradient assessment: hemodynamic principles of aortic stenosis -- 4. Different classifications of aortic stenosis -- 5. Invasive evaluation of aortic stenosis -- 6. Echocardiographic evaluation of aortic valve stenosis -- 7. Complimentary role of CT/MRI in the assessment of aortic stenosis -- 8. Area and gradient mismatch: the discordance of a small valve area and low gradients -- 9. Reverse area and gradient mismatch: the discordance of a large valve area and high gradients -- 10. Prosthetic aortic valves and diagnostic challenges -- 11. Risk prediction models, guidelines, special populations, outcomes -- 12. Surgical management of aortic valve stenosis -- 13. Balloon aortic valvuloplasty -- 14. Imaging for transcatheter aortic valve replacement -- 15. Transcatheter aortic valve replacement -- Index.
  • 2007 Thieme eNeurosurgery
    [ed.] Max Aebi, Vincent Arlet, John K. Webb.
    1. Spinal trauma -- 2. Spinal tumors -- 3. Infections of the spine -- 4. Inflammatory processes -- 5. Deformities of the spine -- 6. Spondyloylysis, spondylolisthesis, and spondyloptosis -- 7. Degenerative spinal diseases -- 8. Metabolic bone disease of the spine: osteoporosis -- 9. Complications in spine surgery -- 10. Documentation, evaluation, and outcome in spine surgery -- Glossary -- Index.
  • 2007 Thieme eNeurosurgery
    [edited by] Max Aebi, Vincent Arlet, John K. Webb ; AOSpine International.
    1. Preface: AO education and teaching concept -- 2. Introduction: AO principles applied to the spine -- 3. History of spine surgery within AO -- 4. Biomechanics of the spine -- 5. Biology of the spine -- 6. Surgical anatomy of the spine -- 7. Spinal instrumentation -- 8. Computer-assisted surgery -- 9. Aneshesia for spine surgery -- Glossary -- Index.
  • 2015 Thieme eNeurosurgery
    guest editors, Ziya Gokaslan, Charles Fisher, Stefano Boriani.
    Evaluation and decision making for metastatic spine tumors / Yan Michael Li, Michael S. Dirks, Claudio E. Tatsui, and Laurence D. Rhines -- Neoplastic spinal instability / Daryl R. Fourney and Charles G. Fisher -- Major complications associated with stereotactic ablative radiotherapy (SABR) for spinal metastasis / Simon S. Lo, Arjun Sahgal, and Eric L. Chang -- En bloc resection in the treatment of spinal metastases : technique and indications / Ilya Laufer, Jean-Paul Wolinksy, and Mark H. Bilsky -- Region specific approaches / Daniel Sciubba -- Spinal reconstruction and fixation/fusion / Rajiv Saigal and Dean Chou -- Minimally invasive surgery for metastatic spine disease / Meic H. Schmidt -- Vertebral augmentation for metastatic disease / Ehud Mendel, Eric Bourekas, and Paul Porensky -- Surgical complications and avoidance / Michelle J. Clarke.
  • 2015 Thieme eNeurosurgery
    guest editors, Ziya Gokaslan, Charles Fisher, Stefano Boriani.
    Evaluation and decision making / Stefano Boriani and Charles Fisher -- Safety and efficacy of surgery for primary tumors of the spine / Daryl R. Fourney, Charles Fisher, and Stefano Boriani -- Interventional options for primary tumors / Sudhir Kathuria -- Radiation therapy for primary bone tumors / Brent Y. Kimball and Yoshiya Yamada -- Medical oncology principles for the spine oncology surgeon / Scott H. Okuno, Steven Robinson and Shreyaskumar Patel -- Spinal osteoid osteoma and osteoblastoma / Melissa Nadeau and Christian DiPaola -- ABC, giant cell / Stefano Boriani, Stefano Bandiera, Riccardo Ghermandi, Simone Colangeli, Luca Amendola, and Alessandro Gasbarrini -- Chordoma / Jackson Sui, Patricia L. Zadnik, Mari L. Groves, and Ziya L. Gokaslan -- Chondrosarcoma / Stefano Boriani, Stefano Bandiera, Riccardo Ghermandi, Simone Colangeli, Luca Amendola, and Alessandro Gasbarrini -- Osteogenic and ewing sarcomas of the spine / Derek G. Ju, Patricia L. Zadnik, and Daniel M. Sciubba -- Margins in spine tumor resection : how much is enough? is planned -- Transgression okay? / Ilya Laufer, Mari Groves, and Jean-Paul Wolinsky -- Principles behind determining the right approach / Nicolas Dea and Rowan Schouten -- Spino-pelvic reconstruction/fixation and fusion / Peter Paul Varga -- Structural graft selection and wound closure techniques -- Complications and avoidance: how to plan primary tumor resection to minimize complications and maximize outcome / Michael C. Oh, Vedat Deviren, and Christopher P. Ames.
  • 2015 Thieme-Connect
    guest editors, Lawrence G. Lenke, Kenneth M.C. Cheung.
    Preoperative evaluation and optimization for surgery / Scott C. Wagner, Daniel G. Kang, Ronald A. Lehman, Jr., and Lawrence G. Lenke -- Decision making in adult deformity surgery : decompression versus short or long fusion / Kenneth M.C. Cheung and Jason P.Y. Cheung -- The use of osteotomies for rigid spinal deformities / Stephen J. Lewis and Simon A. Harris -- Indications and techniques for sacral-pelvic fixation in adult spinal deformity / Kristen E. Jones, Robert A. Morgan, and David W. Polly, Jr. -- Instrumentation strategies in osteoporotic spine : how to prevent failure? / Ahmet Alanay and Caglar Yilgor -- The incidence and management of acute neurologic complications following complex adult spinal deformity surgery / Joseph S. Butler and Lawrence G. Lenke -- Postoperative coronal decompensation in adult deformity / Yong Qiu -- Measuring outcome and value in adult deformity surgery / Robert Waldrop and Sigurd Berven -- Junctional issues following adult deformity surgery / Han Jo Kim, Sravisht Iyer, and Christopher I. Shaffrey, Sr. -- Biomechanics and material science for deformity correction / Manubu Ito, Yuichiro Abe, and Remel Alingalan Salmingo -- Pseudarthrosis and infection / Michael P. Kelly and Sigurd Berven.
  • 2015 Thieme-Connect
    editors: Luiz Roberto Vialle, K. Daniel Riew, and Manabu Ito.
    Laminoplasty for multilevel myelopathy and radiculomyelopathy / Kazuhiro Chiba -- Anterior cervical decompression and fusion techniques : anterior cervical decompression and fusion, corpectomy, and foraminotomy / Han Jo Kim, John M. Rhee, and K. Daniel Riew -- Indications and techniques of cervical pedicle screws c3-7 for degenerative conditions / Kuniyoshi Abumi and Manabu Ito -- Laminectomy and fusion for cervical spondylotic myelopathy / Kristian Dalzell, Aria Nouri, and Michael G. Fehlings -- Posterior cervical minimally invasive microendoscopic foraminotomy / Albert P. Wong, Tarek Y. El Ahmadieh, Zachary A. Smith, Nader S. Dahdaleh, and Richard G. Fessler -- Navigation for cervical reconstruction surgery / Shanmuganathan Rajasekaran and Ajoy Prasad Shetty -- Cervical disk arthroplasty / Justin W. Miller and Rick C. Sasso -- Cervical sagittal balance : what is normal and what is the effect on reconstruction outcomes / Peter L. Cohn, William Ryan Spiker, Kris E. Radcliff, and Alexander R. Vaccaro -- Complications of anterior surgery : vertebral artery injury, esophageal perforation, dysphagia / Luiz Roberto Vialle, Samuel Conrad, and Emiliano Vialle -- Adjacent segment pathology of the cervical spine / Babak Khamsi, Sandeep N. Gidvani, and Jeffrey C. Wang -- Upper cervical screw-fixation techniques : how to avoid complications / Han Jo Kim and Jin Sup Yeom.
  • 2015 Thieme eNeurosurgery
    2015 Thieme-Connect
    series editor, Luiz Roberto Vialle ; guest editors, F. Cumhur Oner, Alexander R. Vaccaro.
    Anatomy of the cervical spine / Ronald L.A.W. Bleys -- Biomechanics of the cervical spine : from the normal state to the injury state / Ahmer K. Ghori, Dana Leonard, and Thomas Cha -- Evaluation of an injured cervical spine / Richard Assaker, Fahed Zairi, and Xavier Demondion -- Nonoperative management of cervical spine trauma / Melvin D. Helgeson and Peter Formby -- Occipital condyle fractures and occipitocervical dissociation / Philipp Schleicher, Matti Scholz, and Frank Kandziora -- Atlas injuries / Matti Scholz, Philipp Schleicher, and Frank Kandziora -- Odontoid fractures, hangman's fractures, and C2 body fractures / Wilco C. Peul and Carmen L.A. Vleggeert-Lankamp -- Compression (AO type-A injuries) / Nuno Neves -- Subaxial cervical spine injuries : distraction (AO type-B injuries) / William A. Robinson, Kevin P. McCarthy, Alexander R. Vaccaro, and C. Chambliss Harrod -- Facet and lateral mass fractures / Maximo-Alberto Diez-Ulloa -- Cervical dislocations (AO type-C injuries) / William Munoz, Michael J. Vives, and Saad B. Chaudhary -- Cervicothoracic junction injuries / Ripul Rajen Panchal -- Cervical trauma in combination with ankylosing spondylitis or diffuse idiopathic skeletal hyperostosis / Jorrit-Jan Verlaan and F. Cumhur Oner -- Rheumatoid arthritis and osteoporosis / David T. Anderson -- Pediatric cervical spine / Ahmet Alanay and Caglar Yilgor.
  • Ken Coar and Rich Bowen.
  • 2014 ProQuest Safari
    Surendra Mohan.
  • 2009 Springer
    edited by Inke S. Näthke, Brooke M. McCartney.
    APC and [beta]-catenin degradation -- Nuclear APC -- APC in cell migration -- The APC-EB1 interaction -- The role of APC in mitosis and in chromosome instability -- Role of APC and its binding partners in regulating microtubules in mitosis -- The adenomatous polyposis coli tumor -- Suppressor and Wnt signaling in the regulation of apoptosis -- APC and its modifiers in colon cancer -- Tissue-specific tumour suppression by APC -- Extra-colonic manifestations of familial adenomatous polyposis coli.
    Also available: Print – 2009
  • 2010
    editors, Bruce C. McLeod, Zbigniew (Ziggy) M. Szczepiorkowski, Robert Weinstein, Jeffrey L. Winters.
    Status: Not Checked OutLane Catalog Record
    1. Development of apheresis instrumentation -- 2. Applications history -- 3. Physiology of apheresis -- 4. Current instrumentation for apheresis -- 5. Selection and care of apheresis donors -- 6. Automated donations: plasma, red cells, and multicomponent donor procedures -- 7. Apheresis platelet collection, storage, quality assessment, and clinical use -- 8. Provision of apheresis platelet transfusions: patient and producer perspectives -- 9. Matched apheresis platelets -- 10. Bacterial contamination of platelet products -- 11. Granulocyte (neutrophil) transfusion -- 12. Management of the therapeutic apheresis patient -- 13. Therapeutic leukocyte and platelet depletion -- 14. Basic principles of therapeutic blood exchange -- 15. Therapeutic apheresis in neurologic disorders -- 16. Therapeutic plasma exchange in hematologic diseases and dysproteinemias -- 17. Therapeutic plasma exchange for renal and rheumatic diseases -- 18. Apheresis in solid organ transplantation -- 19. Red cell exchange and other therapeutic alterations of red cell mass -- 20. Selective extraction of plasma constituents -- 21. Therapeutic apheresis in pediatric patients -- 22. Hematopoietic stem cell transplantation: an overview -- 23. Mobilization and collection of peripheral blood hermatopoietic progenitor cells -- 24. Receipt, processing, and infusion of hematopoietic progenitor and therapeutic cells -- 25. Regenerative medicine -- 26. Autologous cellular immunotherapies -- 27. Allogeneic adoptive immunotherapy with apheresis products -- 28. Photopheresis -- 29. Cellular gene therapy -- 30. Regulatory environment for apheresis facilities and personnel -- 31. Principles of quality management for apheresis facilities -- 32. Quality management of apheresis personnel -- Index.
  • 2015 Springer
    G.M. Anantharamaiah, Dennis Goldberg, editors.
  • 2010 CRCnetBASE
    editor, Victor R. Preedy.
  • 2009 Springer
    edited by Gines Maria Salido and Juan Antonio Rosado.
  • 2015 Springer Protocols
    edited by Gil Mor and Ayesha B. Alvero.
    In Apoptosis and Cancer: Methods and Protocols, Second Edition, expert researches in the field detail the performance of molecular and cellular biology techniques for studying and detecting the activation of the apoptotic pathway. Chapters focus on assays developed to detect its activation not only in vitro but also in vivo, optimized multiplex analysis, medium- to high-throughput screens, and the cellular process. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Apoptosis and Cancer: Methods and Protocols, Second Edition aids scientists as a stand-alone resource for the execution and analysis of the described protocols and as a reference for the study and detection of apoptosis within and outside the area of cancer research.
  • 2008 Springer Protocols
    edited by Gil Mor and Ayesha B. Alvero.
    Modulation of apoptosis to reverse chemoresistance / Gil Mor, Michele K. Montagna, and Ayesha B. Alvero - - Caspase-3 activation is a critical determinant of genotoxic stress-induced apoptosis / Suparna Mazumder, Dragos Plesca, and Alexandru Almasan - - Flow cytometry enumeration of apoptotic cancer cells by apoptotic rate / David Diaz ... [et al.] - - Detection of cancer-related proteins in fresh-frozen ovarian cancer samples using laser capture microdissection / Dan-Arin Silasi ... [et al.] - - Flow cytometric detection of activated caspase-3 / Richard Fox and Martine Aubert - - The chemofx® assay : an ex vivo chemosensitivity and resistance assay for predicting patient response to cancer chemotherapy / Stacey L. Brower, Jeffrey E. Fensterer, and Jason E. Bush -- Correlation of caspase activity and in vitro chemo-response in epithelial ovarian cancer cell lines / Ayesha B. Alvero, Michele K. Montagna, and Gil Mor - - Assessing expression of apoptotic markers using large cohort tissue microarrays / Elah Pick, Mary M. McCarthy, and Harriet M. Kluger -- Mitochondria potential, bax "activation," and programmed cell death / C. Michael Knudson and Nicholas M. Brown -- In vitro and in vivo apoptosis detection using membrane permeant fluorescent-labeled inhibitors of caspases / Brian W. Lee ... [et al.] - - Caspase activity assays / Andrew L. Niles, Richard A. Moravec, and Terry L. Riss - - Multiplex caspase activity and cytotoxicity assays / Andrew L. Niles, Richard A. Moravec, and Terry L. Riss - - Homogeneous, bioluminescent proteasome assays / Martha A. O'Brien ... [et al.] - - A simple method for profiling mirna expression / Jia-Wang Wang and Jin Q. Cheng - - Apoptotic caspase activation and activity / Jean-Bernard Denault and Guy S. Salvesen - - Biochemical analysis of the native trail death-inducing signaling complex / Henning Walczak and Tobias L. Haas - - Laser microdissection sample preparation for RNA analyses / Christopher J. Vega.
  • 2006 Karger
    volume editor, Keith B. Elkon.
    Death receptor signaling and its function in the immune system / Fas, S.C. ... [et al.] -- Inherited and acquired death receptor defects in human autoimmune lymphoproliferative syndrome / Rieux-Laucat, F. -- Tumor necrosis factor ligand-receptor superfamily and arthritis / Hsu, H.-C., Wu, Y., Mountz, J.D. -- Mitochondria, apoptosis and autoimmunity / Pinkoski, M.J., Waterhouse, N.J., Green, D.R. -- Role of Bim and other Bcl-2 family members in autoimmune and degenerative diseases / Hughes, P., Bouillet, P., Strasser, A. -- Mitochondria, cell death, and B cell tolerance / Deming, P.B., Rathmell, J.C. -- Role of complement and other innate immune mechanisms in the removal of apoptotic cells / Ogden, C.A., Elkon, K.B. -- Collectins: opsonins for apoptotic cells and regulators of inflammation / Stuart, L.M., Henson, P.M., Vandivier, R.W. -- MFG-E8-dependent clearance of apoptotic cells, and autoimmunity caused by its failure / Hanayama, R. ... [et al.] -- Clearance of apoptotic cells in human SLE / Gaipl, U.S. ... [et al.] -- Apoptosis and glomerulonephritis / Watson, S. ... [et al.].
  • v. 1-2, 2007. Springer
    v. 2, 2007 Springer
    edited by Rakesh Srivastava.
    BCR-ABL and human cancer / Maria Pérez-Caro and Isidro Sánchez-Garcia -- Angiogenesis and cancer / Yohei Maeshima -- Metastasis: the evasion of apoptosis / Christine E. Horak ... [et al.] -- Carcinogenesis: balance between apoptosis and survival pathways / Dean G. Tang and James P. Kehrer -- Aberrations of DNA damage checkpoints in cancer / Marikki Laiho -- c-Myc, apoptosis, and disordered tissue growth / Michael Khan and Stella Pelengaris -- Role of lysophospholipids in cell growth and survival / Xianjun Fang and Sarah Spiegel -- Alternative use of signaling by the [beta] GBP cytokine in cell growth and cancer control: from surveillance to therapy / Livio Mallucci and Valerie Wells -- Control nodes linking the regulatory networks of the cell cycle and apoptosis / Baltazar D. Aguda, Wee Kheng Yio, and Felicia Ng -- Regulation of NF-[kapa]B function: target for drug development / Daniel Sliva and Rakesh Srivastava -- 5-fluorouracil: molecular mechanisms of cell death / Daniel B. Longley and Patrick G. Johnston -- Apoptosis-inducing cellular vehicles for cancer gene therapy: endothelial and neural progenitors / Gergely Jarmy ... [et al.] -- Apoptosis and cancer therapy / Maurice Reimann and Clemens A. Schmitt -- Coupling apoptosis and cell division control in cancer: the survivin paradigm / Dario C. Altieri -- Clinical significance of histone deacetylase inhibitors in cancer / Sharmila Shankar and Rakesh K. Srivastava.
  • 2009 Springer
    George G. Chen, Paul B.S. Lai, editors.
  • 2007 Springer
    edited by David A. Gewirtz, Shawn E. Holt, Steven Grant.
    The intrinsic pathway of apoptosis -- The extrinsic pathway of apoptosis -- Evaluating the importance of apoptosis and other determinants of cell death and survival -- Mitotic catastrophe -- Autophagy and autophagic cell death -- Regulation and function of detachment-induced cell death (anoikis) in cancer progression and metastasis -- Structure and function of the telomere -- Overview of senescence -- Contributions of telomerase to tumorigenesis -- The role of telomeres in genomic instability -- Overview of the DNA damage checkpoint: ATM and ATR -- Interactions between myc- and cyclin-dependent kinase inhibitors in cancer -- Interplay between [gamma]H2AX and 53BP1 pathways in DNA double-strand break repair response -- DNA-dependent protein kinase in repair, apoptosis, telomere maintenance, and chemotherapy -- Resistance/signaling pathways -- Ceramide and multidrug resistance -- Chemo- and radiosensitization through inhibition of PI3K/Akt signaling -- The advancement of epidermal growth factor receptor inhibitors in cancer therapy -- Antimetabolites -- Topoisomerase I poisons and apoptotic topoisomerase I-DNA complexes -- Perturbations of cellular functions by topoisomerase II inhibitors: all roads lead to cell death? -- The significance of poly-targeting in apoptosis induction by alkylating agents and platinum drugs -- Contributions of apoptosis and senescence to cytotoxicity produced by microtubule-stabilizing agents -- Tyrosine kinase inhibitors -- Monoclonal antibodies in lymphomas -- Role of apoptosis in anti-angiogenic cancer therapies -- Photodynamic therapy-induced apoptosis -- Modulation of TRAIL signaling for cancer therapy.
  • 2010 Springer
    Francesco Cecconi, Marcello D'Amelio, editors.
  • 2009 Springer
    Gáspár Bánfalvi.
  • v. 1-2, 1972. Google Books
    Fulltext Google Books
    Also available: Print – v. 1-2, 1972.
  • 2008 CRCnetBASE
    edited by Ruth B.S. Harris, Richard D. Mattes.
    Food intake : control, regulation, and the illusion of dysregulation / Mark I. Friedman -- The control of food intake and the regulation of body weight in humans / David A. Levitsky -- Appetitive and consummatory aspects of food intake in rodents / Neil E. Rowland and Clare M. Mathes -- Appetite and food intake : a human experimental perspective / Martin R. Yeomans and Emma J. Bertenshaw -- Motivation to eat : neural control and modulation / Dianne Figlewicz Latteman -- Human eating motivation in times of plenty : biological, environmental, and psychosocial influences / Michael R. Lowe, Miriam E. Bocarsly, and Angelo Del Parigi -- Orosensory control of feeding / Thomas R. Scott -- The role of orosensory factors in eating behavior as observed in humans / Didier Chapelot and Jeanine Louis-Sylvestre -- Gastrointestinal factors in appetite and food intake : animal research / Thomas A. Lutz and Nori Geary -- The role of the gastrointestinal tract in satiation, satiety, and food intake : evidence from research in humans / Harry P.F. Peters and David J. Mela -- Postabsorptive endocrine factors controlling food intake and regulation of body adiposity : animal research / Mihai Covasa -- Role of postabsorptive endocrine factors in human feeding and regulation of body adiposity / Karen L. Teff and Chirag Kapadia -- Gastrointestinal sensorineural function in the control of food intake / Gary J. Schwartz -- Conscious and unconscious regulation of feeding behaviors in humans : lessons from neuroimaging studies in normal weight and obese subjects / P. Antonio Tataranni and Nicola Pannacciulli -- Macronutrients : complexity of intake control / Pawel K. Olszewski and Allen S. Levine -- Macronutrients, feeding behavior, and weight control in humans / James Stubbs, Stephen Whybrow, and Nik Mazlan Mamat -- Mineral micronutrient status and food intake : studies with animal models / John Beard -- Mineral and food intake : a human perspective / Dorothy Teegarden and Carolyn Gunther.
  • 2012 Springer
    Hans-Georg Joost, editor.
    The volume Appetite Control provides a comprehensive description of the mechanisms controlling food intake, and thereby energy balance, in the mammalian organism. During the last decade, research in this area has produced a remarkable wealth of information and has characterized the function of numerous peptides, transmitters, and receptors in appetite control. Dysfunction of these circuits leads to obesity, a growing health concern. However, the plethora of mechanistic information is in marked contrasts to an almost complete lack of anti-obesity drugs that meet the safety standards required for the chronic therapy of morbid obesity. Consequently, ongoing research aims to identify additional targets and agents for a pharmacological intervention. Thus, the mechanisms of appetite control as well as all agents interfering with its control are of considerable practical interest.The authors of the volume are distinguished scientists who are leading experts in the field, and who have contributed important, original data to our understanding of the mechanisms of appetite control. They have quite different scientific backgrounds and, together, they represent all relevant disciplines. Thereby, the topics are presented from different points of view, not exclusively from that of pharmacology and neuroendocrinology. Thus, the volume addresses all scientists who are interested in the field of obesity research and the pathophysiology of appetite control.
  • 2008
    Jason Jonathon Hoyt.
    Status: Not Checked OutLane Catalog Record
  • 2013
    edited by E. Başar, C. Başar-Eroğlu, A. Özerdem, P.M. Rossini, G.G. Yener.
  • 2016 Springer
    edited by Xiangdong Wang, Christian Baumgartner, Denis C. Shields, Hong-Wen Deng, Jacques S Beckmann.
    This book elucidates how genetic, biological and medical information can be applied to the development of personalized healthcare, medication and therapies. Focusing on aspects of the development of evidence-based approaches in bioinformatics and computational medicine, including data integration, methodologies, tools and models for clinical and translational medicine, it offers an essential introduction to clinical bioinformatics for clinical researchers and physicians, medical students and teachers, and scientists working with human disease-based omics and bioinformatics. Dr. Xiangdong Wang is a distinguished Professor of Medicine. He is Director of Shanghai Institute of Clinical Bioinformatics, Director of Fudan University Center for Clinical Bioinformatics, Deputy Director of Shanghai Respiratory Research Institute, Director of Biomedical Research Center, Fudan University Zhongshan Hospital, Shanghai, China; Dr. Christian Baumgartner is a Professor of Health Care and Biomedical Engineering at Institute of Health Care Engineering with European Notified Body of Medical Devices, Graz University of Technology, Graz, Austria; Dr. Denis Shields is a Professor of Clinical Bioinformatics at Conway Institute, Belfield, Dublin, Ireland; Dr. Hong-Wen Deng is a Professor at Department of Biostatistics and Bioinformatics, Tulane University School of Public Health and Tropical Medicine, USA; Dr. Jacques S Beckmann is a Professor and Director of Section of Clinical Bioinformatics, Swiss Institute of Bioinformatics, Switzerland.
  • 2008 Springer
    by Gerta Vrbovà, Olga Hudlicka and Kristin Schaefer Centofanti.
  • 2013 Springer
    Arnab De ; with foreword by Jean Martinez.
    Introduction -- Application of prodrug chemistry to GLP-1 -- Experimental procedures -- Characterization of prodrugs -- Conclusion -- Appendix I. Schematic synthesis of longer acting prodrugs -- Appendix II: Structure of peptides in Table A.1 -- Appendix III: Structure of peptides in table A.2 -- Appendix IV: Structure of peptides in table A.3 -- Appendix V: Structure of peptides in table A.4 Appendix VI: Structure of peptides in table A.5 -- Appendix VII. Structure of peptides in table A.6 -- Appendix VIII: Acylataion of HO-His7, GLP(8-37) -- Appendix IX: A note on nomenclature.
  • 2013 Springer
    Michael Kinter, Caroline S. Kinter.
    A key experiment in biomedical research is monitoring the expression of different proteins in order to detect changes that occur in biological systems under different experimental conditions. The method that is most widely used is the Western blot analysis. While Western blot is a workhorse in laboratories studying protein expression and has several advantages, it also has a number of significant limitations. In particular, the method is semi-quantitative with limited dynamic range. Western blot focuses on a single protein per sample with only a small number of representative samples analyzed in an experiment. New quantitative tools have been needed for some time to at least supplement, & possibly replace, the Western blot. Mass spectrometric methods have begun to compete with Western blot for routine quantitative analyses of proteins. One of these methods is based on the tandem mass spectrometry technique of selected reaction monitoring (SRM), which is also called multiple reaction monitoring (MRM). Selected reaction monitoring is actually an older tandem mass spectrometry technique, first described in the late 70s, that is widely utilized in the quantitative analysis of small molecules like drugs & metabolites. The use of selected reaction monitoring for the quantitative analysis of proteins has a number of advantages. Most importantly, it is fundamentally quantitative with a wide dynamic range. The output of the analysis is a numerical result that can range over several orders of magnitude. Other advantages include sufficient specificity & sensitivity to detect low abundance proteins in complex mixtures. Finally, selected reaction monitoring can be multiplexed to allow the quantitative analysis of relatively large numbers of proteins in a single sample in a single experiment. This Brief will explain both the theoretical & experimental details of the selected reaction monitoring experiment as it is applied to proteins.
  • 2015 Springer
    Michele Battle-Fisher.
    This book looks at health policy through the lens of public versus private: population health versus the somatic, social, or emotional experiences of a patient. Rather than presenting policy/ethics as overly technical, this book takes a novel approach of framing public and private health in terms of political philosophy, ethics, and popular examples. Each chapter ties back to the general ethics or political literature as applicable, which are not customarily parts of the current public health curriculum. The author's work on the Orgcomplexity blog has touched on this subject by systemically exploring public policy issues, and the tone of this book mimics the blog with an extension of the arguments.
  • 2011 Springer
    Kewal K. Jain.
  • 2013 Springer
    Kewal K. Jain.
    Culling together excerpts from a wide range of writings by Dr. Kewal K. Jain on biotechnology topics as they relate to disorders of the nervous system, Applications of Biotechnology in Neurology covers a variety of applications for those working in life sciences and the pharmaceutical sciences, particularly those developing diagnostics and therapeutics for the nervous system. This detailed volume delves into areas such as neurobiotechnology, like neurogenomics and neuroproteomics, molecular diagnostics, various methods of improving systemic administration of drugs for targeted delivery to the nervous system, including the use of nanobiotechnology, biotechnology-based strategies and products for neuroprotection, as well as chapters on neurosurgery and personalized neurology.
  • 2014 Springer
    Kewal K. Jain.
    Applications of Biotechnology in Oncology collects key writings by Kewal K. Jain on the most important contributions of biotechnology to cancer research, particularly to the molecular diagnosis of cancer and drug delivery in cancer for personalized management of patients. Basics of various -omics technologies and their application in oncology are described as oncogenomics and oncoproteomics. This detailed volume also explores molecular diagnostics, nanobiotechnology, cell and gene therapies, as well as personalized oncology. With approximately one thousand selected references from recent literature on this topic and numerous tables and figures, Applications of Biotechnology in Oncology serves as an ideal reference for oncologists, scientists involved in research on cancer biology, and physicians in various specialties who deal with cancer.
  • 2005 Springer
    edited by Harinder P.S. Makkar, and Gerrit J. Viljoen.
  • 2007 Springer
    edited by R. Verpoorte, A.W. Alfermann and T.S. Johnson.
    Biosynthesis of plant natural products and characterization of plant biosynthetic pathways in recombinant microorganisms / Erin K. Marasco, Claudia Schmidt-Dannert -- Plant molecular farming: host systems, technology and products / G.B. Sunil Kumar ... [et al.] -- Plastid pathways: metabolic engineering via the chloroplast genom / Tracey Ruhlman, Henry Daniell -- Metabolic engineering of the alkaloid biosynthesis in plants: functional genomics approaches / Kirsi-Marja Oksman-Caldentey, Suvi T. Häkkinen, Heiko Rischer -- Polyamine biosynthetic pathway: a potential target for enhancing alkaloids production: polyamines in alkaloid production / Esha Bhattacharya, M.V.Rajam -- Metabolic engineering in alkaloid biosynthesis: case studies in tyrosine- and putrescine-derived alkaloids: molecular engineering in alkaloid biosynthesis / Fumihiko Sato, Koji Inai, Takashi Hashimoto -- Application of metabolic engineering to vanillin biosynthetic pathways in Vanilla planifolia / Daphna Havkin-Frenkel, Faith C. Belanger -- Pathway engineering of the plant Vitamin C metabolic network / Argelia Lorence, Craig L. Nessler -- Metabolic engineering of terpenoid biosynthesis in plants / Joost Lücker, Harro J. Bouwmeester, Asaph Aharoni -- Metabolic engineering of seed oil biosynthetic pathways for human health / Howard G. Damude, Anthony J. Kinney -- Metabolic engineering in sugarcane: assisting the transition to a bio-based economy / Robert G. Birch -- Single-chain Fv antibody stimulates biosynthesis of secondary metabolites in plants / Waraporn Putalun, Hiroyuki Tamaka, Yukihiro Shoyama -- Metabolic engineering of sulfur assimilation in plants : molecular and biochemical analysis of serine acetyltransferase and cysteine synthase / Masaaki Noji, Kazuki Saito -- Approaches to quality plant based medicine: significance of chemical profiling / Praveen K. Saxena, Ian B. Cole, Susan J. Murch.
  • 2007 NAP
    Committee on Applications of Toxicogenomic Technologies to Predictive Toxicology ; Board on Environmental Studies and Toxicology ; Board on Life Studies ; Division on Earth and Life Studies ; National Research Council of the National Academies.
  • 2012 ScienceDirect
    edited by David T. Curiel, Paul B. Fisher.
    Ch. 1. Cancer terminator viruses and approaches for enhancing therapeutic outcomes -- Ch. 2. Adenovirus strategies for tissue-specific targeting -- Ch. 3. Syrian hamster as an animal model to study oncolytic adenoviruses and to evaluate the efficacy of antiviral compounds -- Ch. 4. Design of improved oncolytic adenoviruses -- Ch. 5. The development of transcription-regulated adenoviral vectors with high cancer-selective imaging capabilities -- Ch. 6. Adenovirus-based immunotherapy of cancer, promises to keep -- Ch. 7. Cancer treatment with gene therapy and radiation therapy -- Ch. 8. Oncolytic adenoviruses for cancer immunotherapy, data from mice, hamsters, and humans -- Index.
  • 2008 CRCnetBASE
    Christopher D. Wickens, Jason S. McCarley.
    Single channel theory and automaticity theory -- Attention control -- Visual attention control, scanning & information sampling -- Visual search -- Spatial attention and displays -- Resources and effort -- Time sharing and multiple resource theory -- Executive control: attention switching, interruptions, and task-management -- Individual differences in attention -- Cognitive neurosciences and neuroergonomics.
  • 2009 Springer
    Johnny L. Matson, editor.
    History and overview / Johnny L. Matson and Daniene Neal -- Applied behavior analysis and its application to autism and autism related disorders / Joel E. Ringdahl, Todd Kopelman, and Terry S. Falcomata -- Assessment methods / Frederick Furniss -- Intervention and treatment methods for children with autism spectrum disorders / Nozomi Naoi -- Differential diagnosis in autism spectrum disorders / Dennis R. Dixon ... [et al.] -- Communication / Jeff Sigafoos, Mark F. O'Reilly, and Giulio E. Lancioni -- Social skills and autism : understanding and addressing the deficits / Mary Jane Weiss, Robert H. LaRue, and Andrea Newcomer -- Rituals and stereotypes / Jeffrey H. Tiger, Karen A. Toussaint, and Megan L. Kliebert -- Self-injury / Timothy R. Vollmer, Kimberly N. Sloman, and Andrew L. Samaha -- Aggression and noncompliance / James K. Luiselli -- Adaptive and self-help skills / Noha F. Minshawi, Iryna Ashby, and Naomi Swievy -- Generalization and maintenance / Angela M. Arnold-Saritepe ... [et al.] -- Training issues unique to autism spectrum disorders / Linda A. LeBlanc, Nicole Gravina, and James E. Carr -- Parent training interventions for children with autism spectrum disorders / Lauren Brookman-Frazee ... [et al.].
  • 2008 Springer
    P.M. Selzer, R.J. Marhöfer, A. Rohwer ; [translators, P.D. Frank Seeber, Conor Caffrey].
  • 2009 CRCnetBASE
    Dhanjoo N. Ghista.
    Analysis for internal fixation of a fractured bone by means of bone-fixator plate -- Human lumbar vertebral body : analysis of its functionally optimal design -- Human spinal intervertebral disc : optimal structural design characteristics -- Biomechanics of fitness index : optimal walking and jogging modes, and hip joint assessment -- Analysis of spinning ball trajectories of soccer kicks and basketball throws -- Mechanics of baseball pitching and batting -- Biodynamics analysis of women's gymnastics : Yurchenko layout vault. Biomechanics in medical diagnosis in the form of nondimensional physiological indices -- Left ventricular mechanics -- Left ventricular contractility indices -- Vascular biomechanics -- Lung ventilation modeling for lung disease diagnosis -- Lung gas-transfer performance analysis -- Indicators for extubation of mechanically ventilated COPD patients using lung ventilation modeling -- Glucose-insulin dynamics modeling -- Glucose tolerance tests modeling -- Modeling of OGTT blood glucose and insulin responses and diagnostic indices --
  • 2016 Springer
    Michael W. Jann, Scott R. Penzak, Lawrence J. Cohen, editors.
    This book is a comprehensive resource on psychotropic medications, detailing the latest methods for defining their characteristics, their use in different patient populations, and drug-drug interactions; an important collection of information forclinicians, students, researchers, and members of the pharmaceutical industry alike. The first section provides the foundational principles of these drugs. Mathematical modeling of parameters that affect their entryto,and exit from, the central nervous system (CNS) compartment are presented on an individual basis and then applied to target populations with specific disease states. Methods and characteristics that inform the transfer of these drugs from the laboratory bench to use in patient care are discussed, including imaging techniques, genetics and physiological barriers, such as the blood-brain barrier. The second section describes the characteristics of specific agents,nominally arranged intodifferent therapeutic categories and with reference crossover use in different disease states. The pharmacologic characteristics of different drug formulations are explored in the context of their ability to improve patient adherence. The third section focuses on drug-drug interactions. Psychotropic medications from different categories are frequently prescribed together,or alongside medications used to treat comorbid conditions, and the information provided is directly relevant to the clinic, as a result. The clinical application of pharmacokinetics and pharmacodynamics of CNS agents has made significant progress over the past 50 years and new information is reported by numerous publications in psychiatry, neurology, and pharmacology.Our understanding of the interrelationship between these medications, receptors, drug transporters, as well as techniques for measurement and monitoring their interactions,isfrequently updated. However, with information presented on a host of different platforms, and in different formats, obtaining the full picture can be difficult. This title aims to collate this information into a single source that can be easily interpreted and applied towards patient care by the clinical practitioner, and act as a reference for all others who have an interest in psychopharmacological agents.
  • 2012 Springer
    editor, Yin Yao Shugart.
    Applied Computational Genomics' focuses on an in-depth review of statistical development and application in the area of human genomics including candidate gene mapping, linkage analysis, population-based, genome-wide association, exon sequencing and whole genome sequencing analysis. The authors are extremely experienced in the area of statistical genomics and will give a detailed introduction of the evolution in the field and critical evaluations of the advantages and disadvantages of the statistical models proposed. They will also share their views on a future shift toward translational biology. The book will be of value to human geneticists, medical doctors, health educators, policy makers, and graduate students majoring in biology, biostatistics, and bioinformatics.
  • 2008 Springer
    Steve H. Murdock, David A. Swanson, editors.
  • 2006
    edited by Ross C. Brownson, Diana B. Petitti.
    Status: Not Checked OutLane Catalog Record
    Epidemiology: a foundation of public health -- Public health surveillance -- Outbreak and cluster investigations -- Systematic reviews in public health -- Epidemiology and risk assessment -- Epidemiologic issues in community intervention -- Outcomes research -- Measuring the quality of health care -- Epidemiology and health policy -- Epidemiology and the law -- Communicating epidemiologic information.
  • 2013 Cambridge
    Jos W.R. Twisk, Department of Epidemiology and Biostatistics, Medical Center and the Department of Health Sciences of the Vrije Universteit, Amsterdam.
    "This book discusses the most important techniques available for longitudinal data analysis, from simple techniques such as the paired t-test and summary statistics, to more sophisticated ones such as generalized estimating of equations and mixed model analysis. A distinction is made between longitudinal analysis with continuous, dichotomous and categorical outcome variables. The emphasis of the discussion lies in the interpretation and comparison of the results of the different techniques. The second edition includes new chapters on the role of the time variable and presents new features of longitudinal data analysis. Explanations have been clarified where necessary and several chapters have been completely rewritten. The analysis of data from experimental studies and the problem of missing data in longitudinal studies are discussed. Finally, an extensive overview and comparison of different software packages is provided. This practical guide is essential for non-statisticians and researchers working with longitudinal data from epidemiological and clinical studies"-- Provided by publisher. "The emphasis of this book lies more on the application of statistical techniques for longitudinal data analysis and not so much on the mathematical background. In most other books on the topic of longitudinal data analysis, the mathematical background is the major issue, which may not be surprising since (nearly) all the books on this topic have been written by statisticians. Although statisticians fully understand the difficult mathematical material underlying longitudinal data analysis, they often have difficulty in explaining this complex material in a way that is understandable for the researchers who have to use the technique or interpret the results. Therefore, this book is not written by a statistician, but by an epidemiologist. In fact, an epidemiologist is not primarily interested in the basic (difficult) mathematical background of the statistical methods, but in finding the answer to a specific research question; the epidemiologist wants to know how to apply a statistical technique and how to interpret the results. Owing to their different basic interests and different level of thinking, communication problems between statisticians and epidemiologists are quite common. This, in addition to the growing interest in longitudinal studies, initiated the writing of this book: a book on longitudinal data analysis, which is especially suitable for the "non-statistical" researcher (e.g. the epidemiologist). The aim of this book is to provide a practical guide on how to handle epidemiological data from longitudinal studies"-- Provided by publisher.
  • 2013 CRCnetBASE
    Geoff Der, Brian S. Everitt.
    "Adding topics useful to medical statisticians, this new edition of a popular intermediate-level reference explores the use of SAS for analyzing medical data. A new chapter on visualizing data includes a detailed account of graphics for investigating data and smoothing techniques. The book also includes new chapters on measurement in medicine, epidemiology/observational studies, meta-analysis, Bayesian methods, and handling missing data. The book maintains its example-based approach, with SAS code and output included throughout and available online"--Provided by publisher.
  • 2013 CRCnetBASE
    Ding-Geng (Din) Chen, Karl E. Peace.
    "Preface In Chapter 8 of our previous book (Chen and Peace, 2010), we briefy introduced meta-analysis using R. Since then, we have been encouraged to develop an entire book on meta-analyses using R that would include a wide variety of applications - which is the theme of this book. In this book we provide a thorough presentation of meta-analysis with detailed step-by-step illustrations on their implementation using R. In each chapter, examples of real studies compiled from the literature and scienti c publications are presented. After presenting the data and sufficient background to permit understanding the application, various meta-analysis methods appropriate for analyzing data are identi ed. Then analysis code is developed using appropriate R packages and functions to meta-analyze the data. Analysis code development and results are presented in a stepwise fashion. This stepwise approach should enable readers to follow the logic and gain an understanding of the analysis methods and the R implementation so that they may use R and the steps in this book to analyze their own meta-data. Based on their experience in biostatistical research and teaching biostatistical meta-analysis, the authors understand that there are gaps between developed statistical methods and applications of statistical methods by students and practitioners. This book is intended to ll this gap by illustrating the implementation of statistical mata-analysis methods using R applied to real data following a step-by-step presentation style. With this style, the book is suitable as a text for a course in meta-data analysis at the graduate level (Master's or Doctorate's), particularly for students seeking degrees in statistics or biostatistics"-- Provided by publisher.
  • 2014 ebrary
    Xiao-Hua Zhou, Chuan Zhou, Danping Liu, Xiaobo Ding.
    Missing data concepts and motivating examples -- Overview of methods for dealing with missing data -- Design considerations in the presence of missing data -- Crosssectional data methods -- Longitudinal data methods -- Survival analysis under ignorable missingness -- Nonignorable missingness -- Analysis of randomized clinical trials with noncompliance.
  • 2006 ScienceDirect
    edited by Dilip K. Arora, Randy M. Berka, Gautam B. Singh.
    The advances in genomic technologies, such as microarrays and high throughput sequencing, have expanded the realm of possibilities for capturing data and analyzing it using automated computer driven bioinformatics tools. With the completion of the sequencing of genomes of human and several model organisms, a quest for scientific discoveries being fueled by integrative and multidimensional techniques in mathematics and computational sciences. In this volume, leading researchers and experts have provided an overview of significant concepts from biological, mathematical, and computational perspectives. It provides a high level view of fungal genomic data integration and annotation, classification of proteins and identification of vaccine targets, identification of secretome or secreted proteins in fungal genomes, as well as tools for analyzing microarray expression profiles. * Provides a survey of theoretical underpinnings on the technological tools and applications * Discusses the tools utilized for the annotation of fungal genomes and addresses issues related to automated annotation generation in a high throughput biotechnology environment * describing the applications of the concepts and methodologies presented throughout the book.
  • 2015 Springer Protocols
    edited by Kewal K. Jain.
    An Overview of Methods Used in Neurogenomics and Their Applications -- Gene Expression-Based Approaches to Understanding Huntington{u2019}s Disease and New Tools for the Interpretation of Expression Datasets -- Location Analysis and Expression Profiling Using Next Generation Sequencing for Research in Neurodegenerative Diseases -- RNA Sequencing from Laser Capture Microdissected Brain Tissue to Study Normal Aging and Alzheimer{u2019}s Disease -- Targeted Re-Sequencing in Psychiatric Disorders -- Role of Neurogenomics in the Development of Personalized Neurology.
  • Peter Sprent and Nigel C. Smeeton..
  • 2008 Springer
    G.O.H. Naumann, L.M. Holbach, F.E. Kruse, eds.
    1 Introduction / G.O.H. Naumann, Friedrich E. Kruse -- 2 General ophthalmic pathology: principal indications and complications, comparing intra- and extraocular surgery / G.O.H. Naumann, F.E. Kruse -- Ch. 3 Special anatomy and pathology in surgery of the eyelids, lacrimal system, orbit and conjunctiva / L.M. Holbach -- 3.1 Eyelids / L.M. Heindl, L.M. Holbach -- 3.2 Lacrimal drainage system / L.M. Heindl, A. Jünemann, L.M. Holbach -- 3.3 Orbit / L.M. Holbach, L.M. Heindl, R.F. Guthoff -- 3.4 Conjunctiva and limbus corneae / C. Cursiefen, F.E. Kruse, G.O.H. Naumann -- 4 General pathology for intraocular microsurgery: direct wounds and indirect distant effects / G.O.H. Naumann, Friedrich E. Kruse -- 5 Special anatomy and pathology in intraocular microsurgery -- 5.1 Cornea and limbus / C. Cursiefen, F.E. Kruse, G.O.H. Naumann -- 5.2 Glaucoma surgery / A. Jünemann, G.O.H. Naumann -- 5.3 Iris / G.O.H. Naumann -- 5.4 Ciliary body / G.O.H. Naumann -- 5.5 Lens and zonular fibers / U. Schlötzer-Schrehardt, G.O.H. Naumann -- 5.6 Retina and vitreous / A.M. Joussen, G.O.H. Naumann -- 5.7 Optic nerve and Elschnig's scleral ring / C.Y. Mardin, G.O.H. Naumann 6 Influence of common generalized diseases on intraocular microsurgery / G.O.H. Naumann, U. Schlötzer-Schrehardt -- 6.1 Diabetes mellitus / G.O.H. Naumann -- 6.2 Arterial hypertension and "vis a tergo" / G.O.H. Naumann -- 6.3 Pseudoexfoliation syndrome: pathological manifestations of relevance to intraocular surgery / U. Schlötzer-Schrehardt, G.O.H. Naumann -- 6.4 Other generalized diseases / G.O.H. Naumann.
  • 2006
    [edited by] Michael E. Burton, Leslie M. Shaw, Jerome J. Schentag ... [et al.].
    Status: Not Checked OutLane Catalog Record
  • 2014 Springer
    Stephan Schmidt, Hartmut Derendorf, editors.
    This comprehensive volume provides an update on the current state of pharmacometrics in drug development. It consists of nineteen chapters all written by leading scientists from the pharmaceutical industry, regulatory agencies and academia. After an introduction of the basic pharmacokinetic and pharmacodynamic concepts of pharmacometrics in drug development, the book presents numerous examples of specific applications that utilize pharmacometrics with modeling and simulations over a variety of therapeutic areas, including pediatrics, diabetes, obesity, infections, psychiatrics, Alzheimer?s disease, and dermatology, among others. The examples illustrate how results from all phases of drug development can be integrated in a more timely and cost-effective process. Applying pharmacometric decision tools during drug development can allow objective, data-based decision making. At the same time, the process can identify redundant or unnecessary experiments as well as some costly clinical trials that can be avoided. In addition to cost saving by expedited development of successful drug candidates, pharmacometrics has an important economic impact in drug product selection. Unsuccessful drug candidates can be identified early and discontinued without expending efforts required for additional studies and allocating limited resources. Hence, pharmacometric modeling and simulation has become a powerful tool to bring new and better medications to the patient at a faster pace and with greater probability of success.
  • 2006 Springer
    Michael R. Pinsky, Laurent Brochard, Jordi Mancebo, editors.
  • 2009 Springer
    M.R. Pinsky, L. Brochard, J. Mancebo, G. Hedenstierna, (eds.).
  • 2012 Cambridge
    edited by Paul Butler, Adam Mitchell, Jeremiah C. Healy.
    1. The skull and brain / Kieran Hogarth, Josef Jarosz and Paul Butler -- 2. Orbit and visual pathway / Indran Davagnanam and Jonathan Hart -- 3. Ear and auditory pathway / Tim Beale and Simon Morley -- 4. Extracranial head and neck / Tim Beale -- 5. The vertebral column and spinal cord / Asif Saifuddin -- 6. Chest and mediastinum / Sheila Rankin -- 7. Heart and great vessels / Simon Padley and Narayan Karunanithy -- 8. Breast / Steve Allan -- 9. The anterior abdominal wall and peritoneum / Nishat Bharwani and Rodney Reznek; -- 10. Abdomen and retroperitoneum / Aslam Sohaib and Navin Ramachandran -- 11. The gastrointestinal tract / Nasir Khan -- 12. The urogenital tract / Uday Patel and Hema Verma -- 13. The male pelvis / Nevin T. Wijisekera and Uday Patel -- 14. The female pelvis / Catriona Avies -- 15. Upper limb / Gajan Rajeswaran and Justin Lee -- 16. Lower limb / Gonzalo Ansede -- 17. Obstetrical imaging / Ian Suchet -- Index.
  • 2009 Springer
    Andrea S. Foulkes.
  • 2007 Springer
    Joaquim P. Marques de Sá.
  • 2012 Wiley
    editors, Andrea J. Fascetti, Sean J. Delaney.
  • 2013 CRCnetBASE
    Robert S. Matson.
    Omics & microarrays revisited -- The commercial microarrays -- Supports & surface chemistries -- The arraying processes -- Gene expression microarray-based applications -- Protein microarray applications -- Multiplex assays.
  • 2012 ScienceDirect
    Rodrigo Zeledón, C. Ben Beard, J.C. Pinto Dias, David A Leiby, Patricia Dorn and Jose Rodrigues Coura.
    During the first half of the 20th century, Chagas disease was assumed to be absent from the U.S. and considered an exotic disease, until the first two indigenous cases were discovered, almost simultaneously, in Texas, 1955. Since that time four indigenous cases have been documented in several places in the country. Although the disease is still considered uncommon in the US, this disease is not longer an exclusive Latin American illness. Physicians in the US are often unaware of the characteristics of the diseases, and are likely overlooking locally acquired cases. The influx of an estimated 300,000 Latin American immigrants with the Chagas parasite means that there is an urgent need for physicians and public health officials to become aware. This title critically reviews old and new literature, help to create greater awareness of the disease in the US and helps in the evaluation of certain epidemiological and public health issues. Helps to create greater awareness of Chagas disease in the USA Helps to evaluate epidemiological and public health issues Facilitates accurate and necessary future public health interventions.
  • 2016 Springer
    edited by David Hui, Alexander A. Leung, Raj Padwal ; with assistance from Christopher Ma.
  • 2011 Springer
    Hui, David; Leung, Alexander K. C.; Padwal, Raj.
  • 2010 CRCnetBASE
    Roger L. Lundblad.
    Introduction to biopharmaceutical conformational analysis : issues and methods -- Comparability of biotechnological/biological products and biological generics -- Application of native electrophoresis for the study of protein conformation -- Affinity chromatography including hydrophobic interaction chromatography in the study of biopolymer conformation -- Size-exclusion chromatography and bimolecular conformation -- Use of analytical ultracentrifugation to study biomolecular conformation -- Use of differential scanning calorimetry to measure conformational change in proteins and other biomacromolecules -- Light scattering and biomacromolecular conformation -- Use of luminescence to measure conformational change in biopharmaceuticals with emphasis on protein and protein drug products -- Near-infrared spectroscopy and macromolecular conformation -- Use of mid-infrared and Fourier transform infrared spectroscopy to study conformation of biomacromolecules -- Use of Raman spectroscopy to evaluate biopharmaceutical conformation -- The use of UV-VIS spectrophotometry for the characterization of biopharmaceutical products -- Use of optical rotatory dispersion and circular dichroism to study therapeutic biomacromolecule conformation -- Use of nuclear magnetic resonance for the characterization of biotherapeutic products -- Use of chemical probes for the study of protein conformation -- Use of hydrogen exchange in the study of biopharmaceutical conformation -- Use of chemical modification for the conformational analysis of biopharmaceuticals -- Use of immunology to characterize biopharmaceutical conformation -- Use of limited proteolysis to study the conformation of proteins of biotechnological interest -- Other technologies for the characterization of conformational change in biopharmaceuticals -- Development of an experimental approach for the study of the conformation of a biological therapeutic product.
  • 2007
    Alex Amies.
    Overview of bioinformatics programming tools and languages; includes working examples.
  • 2007 Springer
    J. Venitz, W. Sittner, editors.
  • 2005
  • NLM
    edited by V.B.D. Skerman, Vicki McGowan, P.H.A. Sneath, on behalf of the Ad Hoc Committee of the Judicial Commission of the International Committee on Systematic Bacteriology.
    Also available: Print – 1989/1980
  • 2009 Springer
    Eric Beitz, editor ; contributors, P. Agre ... [et al.].
  • 2009 ebrary
    by Adam Gacek.
    The main sequence is comprised of approximately 200 entries dealing with almost all aspects of Arabic manuscript studies (codicology and paleography); includes appendices covering abbreviations, letterforms, såurah-headings, major reference works, and a guide to the description of manuscripts, as well as charts of major historical periods and dynasties.
  • 2006 Springer Protocols
    edited by Julio Salinas and Jose J. Sanchez-Serrano.
    Applications of chemical-inducible expression systems in functional genomics and biotechnology / Jianru Zuo, Peter D. Hare, and Nam H. Chua -- RNA extraction / Huazhong Shi and Ray Bressan -- Target preparation for DNA microarray hybridization / Tong Zhu, Sherman H. Chang, and Pedro Gil -- Statistical issues in microarray data analysis / Willem A. Rensink and Samuel Hazen -- Preparation and quality assessment of rna from cell-specific samples obtained by laser microdissection / Regine Kleber and Julia Kehr -- Protein isolation and 2-D electrophroetic separation / Bernhard Schlesier and Hans-Peter Mock -- Isolation of nuclear proteins / Tomasz T. Calikowski and Iris Meier -- Puification and fractionation of membranes for proteomic analysis / Anne Marmagne ... [et al.] -- Protein microsequencing / Alberto Paradela and Juan Pablo Albar -- Peptide-based phosphoproteomics with immobilized metal ion chromatography / Thomas S. Nohse and Scott C. Peck -- Metabolite profiling in arabidopsis / Oliver Fiehn -- Hormone profiling in arabidopsis / Axel Müller, Petra Düchting, and Elmer W. Weiler. EMS mutagenesis of arabidopsis / YongSig Kim, Karen S. Schumaker, and Jian-Kang Zhu -- Low-resolution mapping of untagged mutations / M. Rosa Ponce ... [et al.] -- Gene identification and cloning by molecular marker mapping / Georg Jander -- High-throughput TILLING for arabidopsis / Bradley J. Till ... [et al.] -- Genotyping and mapping with high-density oligonucleotides arrays / Justin Borewitz -- Forward genetic screening of insertional mutants / Anja Schneider and Dario Leister -- PCR-based screening for insertional mutants / Anna N. Stepanova and Jose M. Alonso -- Cytogenetic analysis of arabidopsis / Martin Lysak, Paul Fransz, and Ingo Schubert -- Using information from public arabidopsis databases to aid research / Margarita García-Hernandez and Leonore Reiser -- In planta agrobacterium-mediated transformation by vacuum infiltration / Brian W. Tague and Joanna Mantis -- Transient expression assay by agroinfiltration of leaves / Min Woo Lee and Yinong Yang -- Runctional analysis of transcription factors by microparticle bombardment / Ida Ruberti, Giovanna Sessa, and Giorgio Morelli -- Transfection assays with protoplasts containing integrated reporter genes / Shiv Tiwari ... [et al.] -- Chloroplast genetic engineering via organogenesis or somatic embryogenesis / Amit Dhingra and Henry Daniell -- [beta]Glucuronidase as reporter gene: advantages and limitations / Kye-Won Kim ... [et al.] -- Use of fluorescent proteins as reporters / Guido Jach -- Luciferase as reporter genes / Megan M. Southern, Paul E. Brown, and Anthony Hall -- Aqueorin as reporter gene / Christoph. Plieth -- Growth of plants and preservation of seeds / Luz Rivero-Lepinckas, Deborah Crist, and Randy Scholl -- Prevention and control of pests and diseases / Jenifer Bush, Georg Jander, and Frederick M. Ausubel -- Growth of other species related to Arabidopsis thaliana / Krithika Yogeeswaran and Mikhail Elia Nasrallah -- Grafting / Katherine Bainbridge ... [et al.] -- Synchronization, transformation, and cryopreservation of suspension-cultured cells -- Margit Menges and James A. H. Murray -- Genetic analysis / Maarten Koorneeff, Carlos Alonso-Blanco, and Piet Stam -- QTL analysis / Carlos Alonso-Blanco, Maarten Koornneef, and Johan W. van Ooijen --
  • 2014 Springer Protocols
    edited by Jose J. Sanchez-Serrano, Julio Salinas.
    1. Handling Arabidopsis plants: growth, preservation of seeds, transformation and genetic crosses / Luz Rivero, Randy Scholl, Nicholas Holomuzki, Deborah Crist, Erich Grotewold, and Jelena Brkljacic --2. Using Arabidopsis related model species (ARMS): growth, genetic transformation and comparative gnomics / Giorgia Batelli, Dong-Ha Oh, Matilde Paino D'Urzo, Francesco Orsini, Maheshi Dassanayake, Jian-Kang Zhu, Hans J. Bohnert, Ray A. Bressan and Albino Maggio -- 3. Growing Arabidopsis in vitro: cell suspensions, in vitro culture, and regeneration / Bronwyn J. Barkla, Rosario Vera-Estrella, and Omar Pantoja -- 4. Arabidopsis database and stock resources / Donghui Li, Kate Dreher, Emma Knee, Jelena Brkljacic, Erich Grotewold, Tanya Z. Berardini, Philippe Lamesch, Margarita Garcia-Hernandez, Leonore Reiser and Eva Huala -- 5. Bioinformatic tools in Arabidopsis research / Miguel de Lucas, Nicholas J. Provart, and Siobhan Brady -- 6. Exploiting natural variation in Arabidopsis / Johanna A. Molenaar and Joost J. B. Keurentjes -- 7. Grafting in Arabidopsis / Katherine Bainbridge, Tom Bennett, Peter Crisp, Ottoline Leyser, and Colin Turnbull -- 8. Agrobacterium tumefaciens mediated transient transformation of Arabidopsis thaliana leaves / Silvina Mangano, Cintia Daniela Gonzalez, and Silvana Petruccelli -- 9. iTilling: personalized mutation screening / Susan M. Bush and Patrick J. Krysan --10. Tailor Made Mutations in Arabidopsis Using Zinc-Finger Nucleases / Yiping Qi, Colby G. Starker, Feng Zhang, Nicholas J. Baltes, and Daniel F. Voytas -- 11. The Use of Artificial Micro RNA Technology to Control Gene Expression in Arabidopsis thaliana / Andrew L. Eamens, Marcus McHale, and Peter M. Waterhouse -- 12. Generation and Identification of Arabidopsis EMS Mutants / Li-Jia Qu and Gengi Qin --13. Generation and Identification of Arabidopsis T-DNA Insertion Mutants / Li-Jia Qu and Gengi Qin --14. Identification of EMS-induced Causal Mutations in Arabidopsis thaliana by Next-Generation Sequencing /Naoyuki Uchida, Tomoaki Sakamoto, Masao Tasaka, and Tetsuya Kurata -- 15. Arabidopsis Transformation with Large Bacterial Artificial Chromosomes /Jose M. Alonso and Anna N. Stepanova --16. Global DNA Methylation Analysis Using Methyl-Sensitive Amplification Polymorphism (MSAP) / Mahmoud W. Yaish, Mingsheng Peng, and Steven J. Rothstein --17. Next Generation Mapping of Genetic Mutations Using Bulk Population Sequencing / Ryan S. Austin, Steven P. Chatfield, Darrell Desveaux, and David S. Guttman --18. Chemical Fingerprinting of Arabidopsis Using Fourier-transform Infrared (FT-IR) Spectroscopic Approaches /András Gorzsás and Björn Sundberg -- 19. A Pipeline for ¹⁵N Metabolic Labeling and Phosphoproteome Analysis in Arabidopsis thaliana / Benjamin B. Minkoff, Heather L. Burch, and Michael R. Sussman -- 20. Gene Expression Profiling Using DNA Microarrays / Kyonoshin Maruyama, Kazuko Yamaguchi-Shinozaki, and Kazuo Shinozaki -- 21. Forward Chemical Genetic Screening /Hyunmo Choi, Jun-Young Kim, Young Tae Chang, and Hong Gil Nam -- 22. Highly-Reproducible ChIP-On-Chip Analysis to Identify Genome-Wide Protein Binding and Chromatin Status in Arabidopsis thaliana / Jong-Myong Kim, Taiko Kim To, Maho Tanaka, Takaho A. Endo, Akihiro Matsui, Junko Ishida, Fiona C. Robertson, Tetsuro Toyoda, and Motoaki Seki -- 23. Fluorescence Microscopy / Sebastien Peter, Klaus Harter, and Frank Schleifenbaum -- 24. Immunocytochemical Fluorescent In Situ Visualization of Proteins in Arabidopsis / Yohann Boutté and Markus Grebe --25. High Pressure Freezing and Freeze Substitution of Arabidopsis For Electron Microscopy / Jotham R. Austin, II. -- 26. Applications of Fluorescent Marker Proteins in Plant Cell Biology / Michael R. Blatt and Christopher Grefen -- 27. Flow Cytometry and Sorting in Arabidopsis / David W. Galbraith -- 28. Live Imaging of Arabidopsis Development / Daniel von Wangenheim, Gabor Daum, Jan U. Lohmann , Ernst K. Stelzer, and Alexis Maizel -- 29. Arabidopsis Organelle Isolation and Characterisation / Nicolas L. Taylor, Elke Ströher, and A. Harvey Millar -- 30. Analysis of Subcellular Metabolite Distributions within Arabidopsis thaliana Leaf Tissue: A Primer for Subcellular Metabolomics / Stephan Krueger, Dirk Steinhauser, Jan Lisec, and Patrick Giavalisco -- 31. Hormone Profiling --Gaetan Glauser, Armelle Vallat, and Dirk Balmer -- 32. Purification of Protein Complexes and Characterization of Protein-Protein Interactions / Kirby N. Swatek, Chris B. Lee, and Jay J. Thelen -- 33. Protein Fragment Bimolecular Fluorescence Complementation Analysis for the In vivo Study of Protein-Protein Interactions and Cellular Protein Complex Localizations / Rainer Waadt, Kathrin Schlückling, Julian I. Schroeder, and Jörg Kudla -- 34. The Split Ubiquitin System for the Analysis of Three-Component Interactions Christopher Grefen -- 35. RNA-Binding Protein Immunoprecipitation from Whole Cell Extracts / Tino Köster and Dorothee Staiger -- 36. High Throughput Analysis of Protein-DNA Binding Affinity / José M. Franco-Zorrilla and Roberto Solano.
  • 2013
    Patricia A. Baker, University of Kent.
    "Teaches students and scholars of Greco-Roman medical history how to use and critically assess archaeological materials. Ancient medicine is a subject dominated by textual sources, yet there is a wealth of archaeological remains that can be used to broaden our understanding of medicine in the past. In order to use the information properly, this book explains how to ask questions of an archaeological nature, how to access different types of archaeological materials, and how to overcome problems the researcher might face. It also acts as an introduction to the archaeology of medicine for archaeologists interested in this aspect of their subject. Although the focus is on the Greco-Roman period, the methods and theories explained within the text can be applied to other periods in history."--Dust jacket
  • 1914/9999
    Bonpland, Aimé; Domínguez, Juan A.
    Status: Not Checked OutLane Catalog Record
  • 2007
    publisher and editor-in-chief, Charles A. Fracchia ; editor, Sharon A. Moore ; photo editor, Chris Craig.
    Status: Not Checked OutLane Catalog Record
  • 2011 Springer Protocols
    edited by Tom C. Hobman, Thomas F. Duchaine.
    Purification of native argonaute complexes from the fission yeast Schizosaccharomyces pombe / Shane M. Buker and Mohammad R. Motamedi -- Chromatin immunoprecipitation in fission yeast / Thomas A. Volpe and Jessica DeMaio -- Biochemical analyzes of endogenous argonaute complexes immunopurified with anti-argonaute monoclonal antibodies / Keita Miyoshi ... [et al.] -- Mapping of Ago2-GW182 functional interactions / Bing Yao ... [et al.] -- Continuous density gradients to study argonaute and GW182 complexes associated with the endocytic pathway / Derrick Gibbings -- In vitro RISC cleavage assay / Julia Stoehr and Gunter Meister -- Native gel analysis for RISC assembly / Tomoko Kawamata and Yukihide Tomari -- Purification and assembly of human argonaute, dicer, and TRBP complexes / Nabanita De and Ian J. MacRae -- Detection of human dicer and argonaute 2 catalytic activity / Marjorie P. Perron ... [et al.] -- Imaging the cellular dynamics of drosophila argonaute proteins / Jing Li ... [et al.] -- Live cell imaging of argonaute proteins in mammalian cells / Justin M. Pare, Joaquin Lopez-Orozco, and Tom C. Hobman -- Reporter-based assays for analyzing RNA interference in mammalian cells / Lydia V. McClure, Gil Ju Seo, and Christopher S. Sullivan -- Artificial tethering of argonaute proteins for studying their role in translational repression of target mRNAs / Stephanie Eckhardt ... [et al.] -- Efficient system for Let-7 microRNA and GW182 protein-mediated deadenylation in vitro / Marc R. Fabian, Yuri V. Svitkin, and Nahum Sonenberg -- Cell-free microRNA-mediated translation repression in Caenorhabditis elegans / Edlyn Wu and Thomas F. Duchaine -- Argonaute pull-down and RISC analysis using 2'-O -methylated oligonucleotides affinity matrices / Guillaume Jannot, Alejandro Vasquez-Rifo, and Martin J. Simard -- Cloning argonaute-associated small RNAs from Caenorhabditis elegans / Weifeng Gu ... [et al.] -- Immunoprecipitation of piRNPs and directional, next generation sequencing of piRNAs / Yohei Kirino ... [et al.] -- Generation of an inducible mouse ES cell lines deficient for argonaute proteins / Hong Su and Xiaozhong Wang -- Whole cell proteome regulation by microRNAs captured in a pulsed SILAC mass spectrometry approach / Olivia A. Ebner and Matthias Selbach.
  • 2011 Springer
    Alexander Lerner, Michael Soudry, editors.
    Organization of Urgent Medical Aid, Including Mass Casualty and Triage -- Wound Ballistics and Tissue Damage -- Damage Control Orthopaedics -- Crush Injury of the Limbs and Acute Mechanical Muscle-Crush Compartment Syndrome -- Anesthesia and Intensive Care of the Patient with Severe Extremity Trauma -- Hemotransfusion in Combat Trauma -- Diagnostic Imaging in Combat Trauma -- Tissue Debridement -- Primary External Fixation -- Prevention of Infection and Antibiotic Use in the Management of Armed Conflict Injuries to the Extremities -- Vascular Trauma to the Limbs -- Peripheral Nerve Injury -- Tissue Coverage After War Trauma -- Definitive Bone Fixation and Reconstruction: Conversion from Temporary External Fixation to Internal Fixation Methods -- Definitive Skeletal Reconstruction: Conversion to the Ilizarov Method -- War Injuries of the Hand -- Foot Surgery in War Trauma -- Limb Salvage Versus Amputation: The Dilemma -- Amputation in Combat Trauma -- Delayed Union and Nonunions -- Osteomyelitis -- Chronic Pain Subsequent to Armed Conflict Injuries to the Extremities.
  • 2005 Springer
    Ian Verstegen.
    Arnheim and different approaches to the psychology of art -- Expression, symbolism and visual thinking -- The senses, perceptual objects and their dynamics -- Notorious Gestalt brain model -- Dynamics of pictorial, sculptural and architectural form -- Dynamics of pantomimic form -- Dynamics of musical form -- Dynamics of poetic form -- Art in comparative perspective: children, adults, cultures -- Dynamics of microgenetic artistic development -- Individual artistic development -- Dynamics of differential and psychopathological artistic form -- Dynamics of cultural-perceptual form -- Objective percepts, objective values -- Appendix: life of a psychologist of art.
  • 2006 Springer
    edited by B.J.A. Furr.
  • 2008 Springer
    edited by B.J.A. Furr.
  • 2013 Springer
    Taraneh Shirazian, Erin Gertz, editor-in-chief.
    In the increasingly globalized twenty-first century, cross-cultural communication and knowledge of culturally informed health practices are critical skills for women's health providers. Around the Globe for Women's Health is a concise, culturally sensitive, and clinically relevant guide that aims to increase health equity through prevention and improved clinical care for women around the world. Case-based chapters highlight clinical issues (such as obstetric fistula, malaria, and postpartum hemorrhage) and barriers to care (the unmet need for family planning, or limited radiotherapy in low-resource countries, for example). Around the Globe for Women's Health is a must-have resource not just for physicians considering working in another country, but all providers seeking to provide better care for diverse populations of women within the United States.
  • 2014 CRCnetBASE
    [edited by] Yoel Donchin, Daniel Gopher.
    "This book presents a systematic human factors-based proactive approach to the improvement of health care work and patient safety. The proposed approach delineates a more direct and powerful alternative to the contemporary dominant focus on error investigation and care providers' accountability. It demonstrates how significant improvements in the quality of care and enhancement of patient safety are contingent on a major shift from efforts and investments driven by a retroactive study of errors, incidents and adverse events, to an emphasis on proactive human factors driven intervention and on the development of corresponding conceptual approaches and methods for its systematic implementation"-- Provided by publisher.
  • 2013 Springer Protocols
    edited by Diponkar Banerjee, Sohrab P. Shah.
    Array comparative genomic hybridization : an overview of protocols, applications, and technology trends / Diponkar Banerjee -- Ultradense array CGH and discovery of micro-copy number alterations and gene fusions in the cancer genome / Ewa Przybytkowski [and others] -- Epigenomics : sequencing the methylome / Martin Hirst -- Application of array comparative genomic hybridization in chronic myeloid leukemia / Seonyang Park [and others] -- Use of cytogenetic microarrays in myelodysplastic syndrome Characterization / Lisa G. Shaffer, Blake C. Ballif, and Roger A. Schultz -- CGH protocols : chronic lymphocytic leukemia / Esteban Braggio, Rafael Fonseca, and Neil E. Kay -- Analysis of Acquired genomic copy number aberrations and regions of loss of heterozygosity in acute myelogenous leukemia genomes using affymetrix SNP 6.0 arrays and supporting software tools / Peter D. Ouillette [and others] -- Clinical applications of BAC array-CGH to the study of diffuse large B-cell lymphomas / Cristina Robledo, Juan Luis Garcia, and Jesus M. Hernandez -- Genomic profiling of mantle cell lymphoma / Melissa Rieger Menanteau and Jose A. Martinez-Climent -- Copy number analysis in EBV-positive nodal peripheral T cell lymphoma, unspecified / Kyusam Choi, Hyunjeong Ju, and Young Hyeh Ko -- Mycosis fungoides and Sezary syndrome / Blanca Espinet and Rocio Salgado -- Array CGH reveals clonal evolution of adult T-cell leukemia/lymphoma / Akira Umino and Masao Seto -- Array-CGH analysis of cutaneous anaplastic large cell lymphoma / K. Szuhai [and others] -- Genome-wide DNA profiling of HIV-related B-cell lymphomas / Andrea Rinaldi [and others] -- Array comparative genomic hybridization in osteosarcoma / Bekim Sadikovic [and others] -- Comparative genomic hybridization of Wilms' tumor / Shahrad Rod Rassekh and Evica Rajcan-Separovic -- Array-CGH in childhood MDS / Marcel Tauscher, Inka Praulich, and Doris Steinemann -- Nonfamilial breast cancer subtypes / Markus Ringner, Johan Staaf, and Goran Jonsson -- Applications of array-CGH for lung cancer / Kenneth J. Craddock, Wan L. Lam, and Ming-Sound Tsao -- Array CGH in brain tumors / Gayatry Mohapatra, Julia Sharma, and Stephen Yip -- Finding common regions of alteration in copy number data / Oscar M. Rueda, Ramon Diaz-Uriarte, and Carlos Caldas -- Distinguishing somatic and germline copy number events in cancer patient DNA hybridized to whole-genome SNP genotyping arrays / Gavin Ha and Sohrab Shah.
  • 2014 Springer
    Vsevolod V. Gurevich, editor.
    This volume describes our current understanding of the biological role of visual and non-visual arrestins in different cells and tissues, focusing on the mechanisms of arrestin-mediated regulation of GPCRs and non-receptor signaling proteins in health and disease. The book covers wide range of arrestin functions, emphasizing therapeutic potential of targeting arrestin interactions with individual partners.
  • 2016 Springer
    Massimo Zecchin, Gianfranco Sinagra, editors.
  • 2007 Springer
    Frank I. Marcus, Andrea Nava, Gaetano Thiene (eds.).
  • 2009
    Philippe Lanthony ; translated by Colin Mailer.
    Status: Not Checked OutLane Catalog Record
  • 2006 Springer
    by Narasimhan Ranganathan, Vahe Sivaciyan, Franklin B. Saksena.
    Also available: Print – 2006
  • 2012 Springer
    by Giovanni Boniolo.
    Deliberation and Democracy -- Plato Was Not So Far Wrong: Recalling Athenian Democracy -- A Reappraisal of the Medieval Approach Will Lead to Excellent Deliberators -- Beware of Those Who Think They Possess the Truth! -- Let Us Learn How to Deliberate before Deliberating! -- Between Ethics and Biomedicine.
  • 2015 Springer
    Ivan Izquierdo.
    How do we forget? Why do we need to forget? This book intends to answer to these and other questions. It aims to demonstrate that each one is who it is due to their own memories. Thus, distinguish between the information we should keep from those we should forget is an difficult art. In this book, the author discusses about the different types of memory, the main types of forgetting (avoidance, extinction and repression), their brain areas and their mechanisms. In this sense, the art of forgetting, or the art of do not saturate our memory mechanisms, is something innate, that benefits us anonymously, keeping us from sinking amidst our own memories. The essays that compose this book go through several aspects, since individuals to societies' memory. By the end of the book, the reader will be able to understand that we forget to be able to think, to live and to survive.
  • 2015 Cambridge
    Miranda Brown.
    Attendant He : innovator or persona? -- Bian Que as a seer : political persuaders and the medical imagination -- Chunyu Yi : can the healer speak? -- Liu Xiang : the imperial library and the creation of the exemplary healer list -- Zhang Ji : the kaleidoscopic father -- Huangfu Mi : from innovator to transmitter.
  • 2006 ProQuest Safari
    Stephane Faroult with Peter Robson.
  • 2012 Springer
    Colin A. Nurse, Constancio Gonzalez, Chris Peers, Nanduri R. Prabhakar, editors.
    Also available: Print – 2012
  • 2009 Springer
    [edited by] Constancio Gonzalez, Colin A. Nurse, Chris Peers.
    Also available: Print – 2009
  • 2006 Springer
    edited by Yoshiaki Hayashida, Constancio Gonzalez and Hisatake Kondo.
    A tribute to Professor Autar Singh Paintal -- Structure of chemoreceptors -- Developmental aspects of chemoreceptors -- Molecular biology of chemoreceptors -- Biophysics of ionic channels in chemoreceptors -- Central integration and systemic effects of chemoreflex -- Mechanisms of chemoreceptions.
    Also available: Print – 2006
  • 2015 Springer
    Chris Peers, Prem Kumar, Christopher Wyatt, Estelle Gauda, Colin A. Nurse, Nanduri Prabhakar, editors.
    Every three years, the International Society for Arterial Chemoreception (ISAC) arranges a Meeting to bring together all of the major International research groups investigating the general topic of oxygen sensing in health and disease, with a prime focus upon systemic level hypoxia and carotid body function. This volume summarises the proceedings of the XIXth meeting of the Society, held in Leeds, UK during the summer of 2014. As such this volume represents a unique collection of state of the art reviews and original, brief research articles covering all aspects of oxygen sensing, ranging from the molecular mechanisms of chemotransduction in oxygen sensing cells such as the carotid body type I cells, to the adverse, reflex cardiovascular outcomes arising from carotid body dysfunction as seen, for example, in heart failure or obstructive sleep apnoea. This volume will be of tremendous interest to basic scientists with an interest in the cellular and molecular biology of oxygen sensing and integrative, whole organism physiologists as well as physicians studying or treating the clinical cardiovascular consequences of carotid body dysfunction.
    Also available: Print – 2015
  • 2015 Springer
    Adel Berbari, Giuseppe Mancia, editors.
    As our knowledge about arterial disease is greatly expanding, the aim of this book is to explore all aspects of arterial pathology, including classification, clinical manifestations, pathogenesis, and therapeutic options. The discussion of pathophysiologic mechanisms of arterial disease is wide ranging, encompassing hemodynamic, metabolic, humoral, inflammatory, genetic and environmental factors. Particular emphasis is placed on recent concepts, such as: the role of age-associated arterial alterations in the initiation and progression of cardiovascular diseases in older persons, the importance of mineral metabolism-bone vascular interactions, the clinical and prognostic significance of the renal resistive index, retinal circulation, toxemia of pregnancy as an arterial disease, and the role of pulmonary/vascular interaction in pulmonary hypertension and cross-talk of macrocirculation and microcirculation in target organ involvement. Evaluation procedures are carefully explained, and the full range of currently available therapeutic options, including lifestyle modifications and pharmacologic approaches, are described and appraised.
  • 2006 Springer
    Guo-Wei He (ed.) ; foreword by Denton A. Cooley ; contributions by Floyd D. Loop ... [et al.].
  • 2015 Springer
    Hans Scholz ; in collaboration with U. Krüger, K. Petzold, and W. Munsch ; with extra chapters by J. Janzen and U. Krüger.
  • 2010 ClinicalKey
    edited by J. Chris Coetzee, Shepard R. Hurwitz.
    Ankle arthritis: preoperative considerations -- Evaluation of the arthritic ankle and foot -- Ankle arthritis etiology and prevention -- Nonoperative management of ankle arthritis -- Functional assessment of patients with ankle arthritis -- Young arthritic ankle: treatment options -- Ankle arthroscopy -- Tibial osteotomy for ankle arthritis -- Allograft resurfacing of the tibiotalar joint -- Distraction arthroplasty for the treatment of ankle arthritis -- Young arthritic ankle: treatment options in arthrodesis -- Primary ankle replacement -- Challenging primary total ankle arthroplasty -- Use of total ankle arthroplasty in the varus or valgus ankle -- Associated angulatory (tibia and fibula) deformities -- Challenging total ankle arthroplasty: management of associated foot pathology -- Complications of total ankle arthroplasty: avoidance and treatment -- Recurrent varus following total ankle arthroplasty -- Recurrent valgus following total ankle arthroplasty -- Syndesmosis fusion in the agility total ankle arthroplasty -- Periprosthetic fractures: intraoperative and postoperative -- Infection in total ankle arthroplasty -- Infection following total ankle arthroplasty -- Revision total ankle arthroplasty -- Diagnosis and classification of bone defects: the effect on total ankle arthroplasty -- Recognition and salvage of the failed ankle replacement arthroplasty -- Longevity of modern ankle replacement arthroplasty: survivorship and mechanisms of failure -- Revision of total ankle replacement -- Conversion of a failed total ankle replacement to an ankle fusion: indications and technique -- Subtalar arthritis -- Nonoperative treatment -- Arthroscopy of the subtalar joint -- Subtalar fusion -- Arthrodesis with realignment -- Acquired flatfoot -- Adult acquired flatfoot: nonoperative treatment -- Tendon transfers for acquired posterior tibial tendon deficiency -- Treatment of stage 2 posterior tibial tendon dysfunction -- Treatment of the stage 4 flatfoot -- Tarsometatarsal arthritis -- Midfoot arthritis: nonoperative treatment and arthrodesis -- Great toe (metatarsophalangeal joint) arthritis -- Hallux rigidus etiology -- Hallux rigidus: conservative treatment -- Surgical treatment -- Cheilectomy and phalangeal osteotomy -- Interpositional grafting -- Fusion: when and how -- Replacement: unipolar options and rationale -- Replacement: bipolar options and rationale -- Failed great toe arthroplasty -- Surgical management of failed great toe arthroplasty.
  • 2010 ClinicalKey
    edited by A. Bobby Chhabra, Jonathan E. Isaacs.
    Diagnosis, evaluation, and conservative treatment of posttraumatic arthritis and osteoarthritis of the wrist / Mathew Blake, Jonathan E. Isaacs -- The role of arthroscopic evaluation and debridement in wrist arthritis / Laura E. Gill, A. Bobby Chhabra -- Partial and complete denervation of the wrist / David Schnur -- Posttraumatic radiocarpal arthritis / Jonathan E. Isaacs, Travis M. Hendry -- SLAC and SNAC wrist / Warren Hammert -- Scaphotrapeziotrapezoidal (STT) arthritis / Jack Ingari -- Ulnar impaction syndrome / Sarah Pettrone ... [et al.] -- Distal radioulnar joint arthritis / Paul Nassab, Jonathan E. Isaacs -- Total wrist arthrodesis and total wrist arthroplasty / Steven D. Maschke, Thomas J. Graham -- Rheumatoid and other inflammatory arthritides of the wrist / Marco Rizzo -- Surgical treatment of the arthritic wrist : the future / Joshua P. Moss, Peter J. Stern -- Distal interphalangeal joint arthritis / James Fletcher -- Proximal interphalangeal joint arthritis / Stephen J. Leibovic -- Metacarpophalangeal arthritis / John Thaller -- Thumb carpometacarpal arthritis / Peter G. Fitzgibbons, Arnold-Peter C. Weiss -- The future of treatment for arthritis of the hand / Scott A. Eisenhuth, A. Bobby Chhabra -- Arthroscopic treatment of the arthritic elbow / Sara D. Rynders, Chad. R. Manke -- Surgical treatment of the elbow : surgical options and indications / Travis M. Hendry, Robert Chadderdon, N. Douglas Boardman III -- Ulnohumeral arthroplasty / Dan A. Zlotolow, Michael O'Brien -- Resurfacing elbow replacement arthroplasty / Rick Papandrea, Peter Evans -- Total elbow arthroplasty / Cay Mierisch, Cassandra Mierisch -- Revision total elbow arthroplasty / N. Douglas Boardman III -- Interposition arthroplasty of the elbow / César J. Bravo -- Elbow arthrodesis / Namory D. Bagayoko, A. Bobby Chhabra -- The future : surgical options for the arthritic elbow / R.A. Gallo, A.H. Payatakes, D.G. Sotereanos.
  • 2009 ClinicalKey
    edited by Thomas E. Brown [and others].
    Etiology of Hip Arthritis -- Etiology of Hip Arthritis -- Preoperative Planning for Hip Surgery -- Hip Arthroscopy -- Surgical Dislocation of the Adult Hip for Treatment of Femoroacetabular Impingement -- Periacetabular Osteotomy -- Proximal Femoral Osteotomy -- Salvage Osteotomy -- Arthrodesis -- The Primary Cemented Femoral Stem -- Current Designs of Uncemented Total Hip Arthroplasty -- Acetabular Component Options in Total Hip Arthroplasty -- Bearing Options in Total Hip Arthroplasty -- Hip Resurfacing Arthroplasty -- Hip Resurfacing Arthroplasty -- Total Hip Arthroplasty in Developmental Dysplasia of the Hip -- Total Hip Arthroplasty : Juvenile Rheumatoid Arthritis -- Proximal Femoral Deformity -- Proximal Femoral Deformity -- Proximal Femur Fracture : The Challenging Primary Total Hip Arthroplasty -- Rationale and Expectations -- Mini-Posterior Total Hip Arthroplasty -- Mini Lateral Approach Total Hip Arthroplasty : The Anterolateral Approach (Modified Hardinge) -- Single-Incision Direct Anterior Approach for Total Hip Arthroplasty -- The Minimally Invasive Total Hip Arthroplasty with Two Incisions -- Treatment Options for Osteonecrosis of the Hip -- Limb-Length Discrepancy after Total Hip Arthroplasty : Avoidance and Treatment -- Neurovascular Injury : Avoidance and Treatment -- Instability after Total Hip Arthroplasty : Issues, Avoidance, and Treatment -- Periprosthetic Fractures around Total Hip Arthroplasty : Evaluation and Management -- Evaluation and Treatment of Infected Total Hip Arthroplasty -- Infected Total Hip Arthroplasty : Future Problems and Potential Solutions -- Component Removal : Tricks of the Trade -- Diaphyseal Fixation : Providing Durable Femoral Revisions with Extensively Porous Coated Stems -- Cemented Long Stems for Revision Total Hip Arthroplasty : Do's and Don'ts -- Impaction Grafting of the Femur -- Tapered, Fluted Femoral Fixation -- Allograft-Prosthesis Composites -- Megaprosthesis for Severe Femoral Bone Loss : Heavy Metal -- Liner Exchange and Surgical Treatment of Osteolysi -- Hemispheric Press-Fit Components : The Workhorse -- Triflange Acetabular Components : Last Hurrah.
  • 2009 ClinicalKey
    edited by Thomas E. Brown [and others].
    Arthroscopic Debridement of the Arthritic Knee : Is There Still a Role? -- Cartilage Repair and Replacement : From Osteochondral Autograft Transfer to Allograft -- Distal Femoral Osteotomy for Genu Valgum -- Principles of Correction for Monocompartmental Arthritis of the Knee -- Unicompartmental Knee Arthroplasty -- Patellofemoral Arthroplasty -- Surgical Approaches for Primary Total Knee Arthroplasty : Old and New -- Soft Tissue Balancing during Total Knee Arthroplasty -- Sizing and Balancing : Gap Technique versus Measured Resection -- Posterior Cruciate Ligament Retaining Total Knee Arthroplasty -- Posterior Stabilized Total Knee Arthroplasty -- Mobile-Bearing Total Knee Arthroplasty -- Intraoperative Complications during Total Knee Arthroplasty : How to Get Out of Trouble -- Minimally Invasive Total Knee Arthroplasty -- Evaluation of the Painful/Failed Total Knee Arthroplasty -- Soft Tissue Issues : Exposure and Coverage -- Surgical Exposure in Total Knee Arthroplasty -- Removal of Well-Fixed Components during Revision Total Knee Arthroplasty -- Balancing the Revision Total Knee Arthroplasty : Restraint with Constraint -- Management of Bone Loss : Structural Grafts in Revision Total Knee Arthroplasty -- Addressing Ligament Deficiency in Revision Total Knee Arthroplasty -- Adjunctive Fixation in Total Knee Arthroplasty Revision : Stems and Sleeves -- Revision Total Knee Arthroplasty Using Mobile-Bearing Technology -- Patella Revision/Reconstruction -- The Infected Primary Total Knee Arthroplasty -- Patellofemoral Maltracking : Identification and Solutions -- Extensor Mechanism Rupture -- Extensor Mechanism Rupture -- The Stiff Total Knee Arthroplasty : Evaluation and Treatment -- Periprosthetic Fractures about Total Knee Replacements : Repair or Revise -- Limb Salvage for Failed Total Knee Arthroplasty : Arthrodesis and Beyond.
  • 2009 ClinicalKey
    edited by David M. Dines, Cato T. Laurencin, Gerald R. Williams, Jr.
    Arthritis and arthroplasty of shoulder -- Etiology, diagnosis, and non-operative treatment of the arthritic shoulder -- Surgical options in shoulder arthritis -- Debridement, chondroplasty, and soft tissue releases -- Evolution of shoulder arthroplasty -- Partial surface replacements: indications, techniques, and results -- Humeral head resurfacing: indications, technique, and results -- Hemiarthroplasty for arthritis -- Interpositional arthroplasty -- Total shoulder arthroplasty in primary osteoarthritis: technique and results -- Total shoulder arthroplasty: technical considerations -- Soft tissue releases and glenoid exposure -- Glenoid bone loss treated with bone grafts -- Rotator cuff deficient arthritic shoulder -- Rehabilitation after shoulder arthroplasty -- Disease-specific options -- Arthroplasty in rheumatologic conditions: special considerations -- Total shoulder arthroplasty or hemiarthroplasty for arthritis: current trends and technical considerations -- Shoulder arthroplasty in post-traumatic arthroplasty: technique and results -- Arthroplasty for arthritis after instability, including post-capsulorrhaphy and chronic dislocations -- Avascular necrosis of the shoulder -- Reverse shoulder arthroplasty: indications, technique, and results -- Reverse shoulder prosthesis for acute and chronic fractures -- Complications and revision -- Complications of conventional shoulder arthroplasty -- Complications and treatment of reverse shoulder prosthesis -- Infection: diagnosis and treatment options -- Soft tissue failure after arthroplasty: rotator cuff and subscapularis -- Glenoid loosening: diagnosis and treatment -- Revision shoulder arthroplasty: technical considerations and outcomes -- Reverse shoulder arthroplasty in revision shoulder arthroplasty.
  • 2010 ClinicalKey
    edited by Francis H. Shen, Christopher I. Shaffrey.
    Preoperative Evaluation of the Spine -- Imaging of the Spine -- Pathophysiology of Degenerative Processes of the Spine -- Cervical Disc Degeneration -- Treatment of Axial Neck Pain -- Cervical Radiculopathy -- Cervical Myelopathy -- Posttraumatic Arthritis of the Cervical Spine : Operative and Nonoperative Management -- Posttraumatic Deformities of the Cervical Spine : Operative Management -- Rheumatoid Arthritis of the Cervical Spine -- Rheumatoid Arthritis of the Cervical Spine -- Surgical Management of Thoracic Stenosis with Myelopathy -- Video-Assisted Thoracoscopy for the Treatment of Thoracic Degenerative Disorders -- Microdiscectomy for the Treatment of the Herniated Lumbar Disc -- Far Lateral Lumbar Disc Herniations -- Lumbar Laminectomy for the Treatment of Spinal Stenosis -- Indications for Fusion for Degenerative Disorders of the Lumbar Spine -- Instrumentation of the Lumbar Spine for Degenerative Disorders -- Posterior Approach for the Treatment of Lumbar Degenerative Disorders : Axial Back Pain -- Anterior Approach for the Treatment of Lumbar Degenerative Disorders : Axial Back Pain -- Anteroposterior Approach for the Treatment of Lumbar Degenerative Disorders : Axial Back Pain -- Posterior Lumbar Interbody Fusion for Degenerative Disorders of the Spine -- Extreme Lateral Approach for Degenerative Disorders of the Spine -- Management of Postoperative Lumbar Wound Infections -- How to Choose the Surgical Approach for the Treatment of De Novo Scoliosis -- Posterior Laminectomy without Fusion for the Treatment of De Novo Scoliosis -- Fusion in Adult Scoliosis -- Sacropelvic Instrumentation for Disorders of the Thoracolumbar Spine -- Osteotomies for Degenerative Disorders of the Thoracolumbar Spine -- Spinal Deformities in Ankylosing Spondylitis : Surgical Management -- Instrumentation in the Osteoporotic Spine -- Nonunion of the Cervical Spine : Anterior and Posterior Treatment -- Junctional Degeneration of the Cervical Spine -- Postlaminectomy Kyphosis : Anterior, Posterior, and Combined Approaches -- Failure of Cervical Spine Instrumentation -- Adjacent-Level Degeneration of the Lumbar Spine after Lumbar Fusion -- Failure of Lumbar Spine Instrumentation -- Evaluation and Management of Postoperative Wound Infections of the Anterior and Posterior Spine -- Management of Cerebrospinal Fluid Leaks in the Lumbar Spine -- Vertebroplasty for the Treatment of Vertebral Body Fractures -- Kyphoplasty for the Treatment of Vertebral Body Fractures -- Posterior Minimally Invasive Decompressive Techniques for the Cervical Spine -- Posterior Minimally Invasive Decompressive Techniques for the Lumbar Spine -- Minimally Invasive Surgical Techniques for Pedicle Screw Placement -- Posterior Minimal Incision Interbody Fusion Techniques for the Lumbar Spine -- Posterior Motion-Sparing Instrumentation and Interspinous Devices for the Treatment of Degenerative Disorders of the Lumbar Spine -- Disc Arthroplasty for the Treatment of Degenerative Disorders of the Lumbar Spine -- Facet Joint Replacement for the Treatment of Degenerative Disorders of the Spine -- Use of Nucleus Replacement for the Treatment of Degenerative Disorders of the Lumbar Spine.
  • 2005 Ovid
    edited by William J. Koopman and Larry W. Moreland.
    Sect. I. Introduction to the study of the rheumatic diseases -- Sect. II. Scientific basis for the study of the rheumatic diseases -- Sect. III. Therapeutic approaches in the rheumatic diseases -- Sect. IV. Surgical intervention in the rheumatic diseases -- Sect. V. Rheumatoid arthritis -- Sect. VI. Other inflammatory arthritis syndromes -- Sect. VII. Systemic rheumatic diseases -- Sect. VIII. Vasculitis and related diseases -- Sect. IX. Miscellaneous rheumatic diseases -- Sect. X. Regional disorders of joints and related structures -- Sect. XI. Osteoarthritis -- Sect. XII. Metabolic bone and joint diseases -- Sect. XIII. Infectious arthritis.
    Also available: Print – v. 1-2, 2005.
  • Brower, Anne C.; Flemming, Donald J.
    Status: Not Checked OutLane Catalog Record
  • 2012 ScienceDirect
    2012 ClinicalKey
    Anne C. Brower, Donald J. Flemming ; associate editor, Stephanie A. Bernard.
    Imaging techniques and modalities -- Evaluation of the hand film -- Approach to the foot -- Approach to the hip -- Approach to the knee -- Approach to the shoulder -- The sacroiliac joint -- The "phytes" of the spine -- Radiographic changes observed in a specific articular disease -- Rheumatoid arthritis -- Psoriatic arthritis -- Reactive disease -- Ankylosing spondylitis -- Osteoarthritis -- Neuropathic osteoarthropathy -- Diffuse idiopathic skeletal hyperostosis -- Gout -- Calcium pyrophosphate dihydrate crystal deposition disease -- Hydroxyapatite deposition disease -- Miscellaneous deposition diseases -- Collagen vascular diseases (connective tissue diseases) -- Juvenile idiopathic arthritis -- Hemophilia -- Mass-like arthropathies.
  • 2006
    edited by Ilona S. Szer ... [et al.].
    Status: Not Checked OutLane Catalog Record
  • 2009 ClinicalKey
    Michael A. Bruno, Timothy J. Mosher, Garry E. Gold.
    Arthritis in Color helps you understand the recent advances in the use of magnetic resonance imaging and ultrasound for the diagnosis and treatment of arthritis. Written by three authorities in the field, Michael A. Bruno, MD; Gary E. Gold, MD; and Timothy J. Mosher, MD, and including more than 600 images, 300 in full color, this book gives you access to the current understanding and future directions in this dynamic field. With coverage of everything from the basic to the advanced, you'll have the guidance you need to make the most accurate diagnoses. Provides correlation images that depict the disease process on ultrasound, MRI, and plain radiographs to allow you to confirm a diagnosis quickly and easily. Explores MRI and ultrasound as more effective approaches to diagnosing rheumatoid arthritis and osteoarthritis due to their superior evaluation of soft tissues, marrow, and cartilage. Features more than 600 digital quality images, 300 in full color, that clearly illustrate the material being presented. Includes examples of pathology with color illustrations to help you arrive at more accurate diagnoses. Covers both basic and advanced concepts for a well-rounded, well-balanced approach suitable for the novice or the expert. Presents the expert guidance of Michael A. Bruno, Gary E. Gold, and Timothy J. Mosher, instructors of the popular annual course at the American Roentgen Ray Society on Advanced Imaging in Arthritis, for a consistent, accessible style.
  • 2011 CRCnetBASE
    edited by Debasis Bagchi, Hiroyoshi Moriyama, and Siba P. Raychaudhuri.
    Section I. Overview and pathophysiology -- 1. An overview on rheumatologic disorders / S. Kumar and Rajiva Gupta -- 2. Pathogenesis of osteoarthritis / Allen P. Anandarajah -- 3. Biomarkers in osteoarthritis / Muneaki Ishijima, Hisashi Kurosawa, Haruka Kaneko, Kazuo Kaneko -- 4. Rheumatoid arthritis: disease pathophysiology / Ankit Saxena, Smriti K. Raychaudhuri -- 5. Osteoclasts and interleukin-17-producing helper T cells in rheumatoid arthritis / Kazuo Okamoto, Hiroshi Takayanagi -- 6. WNT/β-Catenin signaling modulating osteoarthritis / Maripat Corr -- 7. Psoriatic arthritis: epidemiology, risk factors, and quality of life / Arathi R. Setty -- Section II. Consequences -- 8. Arthritis, obesity, increased cardiovascular risk, and disability / Shampa Chatterjee -- Section III. Antiarthritic drugs -- 9. An Overview: use of traditional antiarthritic drugs and update on drug development / Gabriela Schmajuk, Michael G. Lyon -- 10. Nonsteroidal anti-inflammatory drugs / Anand Lal, Seeta Sharma -- 11. Biologics: target-specific treatment of systemic and cutaneous autoimmune diseases / Siba P. Raychaudhuri and Smriti K. Raychaudhuri -- 12. Topical applications for pain and arthritic diseases / Norifumi Tanida, Kotaro Maekawa, Masaru Nakanishi -- 13. Hyaluronic acid and arthritis: a review / Michele Abate -- 14. Hyaluronan for the treatment of osteoarthritis and rheumatoid arthritis / Toshiaki Nakano, Yasufumi Takahashi -- Section IV. Natural therapeutic interventions -- 15. Immunomodulatory activities of Japanese traditional medicines in rheumatoid arthritis / Toshiaki Kogure -- 16. An Overview on natural therapeutic interventions / Stanley Naguwa -- 17. Potential health benefits from nutrition and dietary supplements in the prevention of osteoarthritis and rheumatoid arthritis / Cathy Creger Rosenbaum -- 18. Antiarthritic potential of glucosamine and chondroitin: an overview / Michael W. Orth, Pooi-See Chan -- 19. An Overview on N-Acetylglucosamine and arthritis / Daiki Kubomura, Uzuka Naoaki, Yoshiharu Matahira -- 20. Hexosamine flux and the efficacy and safety of glucosamine in the treatment of osteoarthritis / Akhtar Afshan Ali, William Salminen, Julian E. Leakey -- 21. Safety and efficacy of a unique undenatured type II collagen in the treatment of arthritis / Ramesh C. Gupta, Hiroyoshi Moriyama, Manashi Bagchi, Francis C. Lau, Debasis Bagchi -- 22. Targeting inflammatory pathways by nutraceuticals for prevention and treatment of arthritis / Bokyung Sung, Gautam Sethi, Kwang Seok Ahn, Manoj K. Pandey, Ajaikumar B. Kunnumakkara, Bharat B. Aggarwal -- 23. Boswellia serrata for arthritis relief: a journey from frankincense to aflapin and 5-Loxin / Alluri Venkata Krishnaraju, Krishanu Sengupta, Golakoti Trimurtulu -- 24. Utilization of marine products in the treatment and prevention of osteoarthritis / Tadakazu Tamai, Ayako Honmura, Hisashi Yoshioka, Tatsuya Konishi, Shisei Kuninaga, Hiroshi Oda, Akinori Sakamoto, Tsuyoshi Okada -- 25. Benefits of fish oil for rheumatoid arthritis: a review / Christine Dawczynski, Gerhard Jahreis -- 26. Potential health benefits of n-3 and -6 fatty acids in selected plant seed oils in rheumatoid arthritis / Hiroyuki Takeuchi, Hiroyoshi Moriyama, Debasis Bagchi -- 27. Antiarthritic potential of bromelain from Ananas comosus and its combination / Dilip Ghosh -- 28. Anti-inflammatory properties of Zingiber officinale var. rubra (red ginger extract) / Hiroshi Shimoda -- 29. Benefits of radix Tripterygium wilfordii for rheumatoid arthritis / Xiaojuan He, Shaohua Xu, Miao Jiang, Na Lin, Aiping Lu -- 30. Dehydroepiandrosterone (DHEA): a review of its preclinical use in the management of osteoarthritis / Kai Huang, Hai-li-Cai, Chun Zhang, Xiao-wen Zhang, Li-dong Wu, Li-feng Shen, and Qiao-feng Guo -- 31. Antiarthritic potential of green-lipped mussel and other marine-based nutraceuticals / Wendy Pearson, Michael I. Lindinger -- 32. Antioxidant, anti-inflammatory, and anticatabolic potential of rosmarinic acid and high-rosmarinic acid mint (Mentha Spicata) in osteoarthritis Wendy Pearson, Michael I. Lindinger -- 33. Potential health benefits of orally administered hyaluronan in alleviating knee joint pain / Tomoyuki Kanemitsu, Akira Asari -- 34. Pycnogenol - a nutraceutical for osteoarthritis / Om P. Gulati -- Section V. Orthopedic approach -- 35. Total knee arthroplasty for osteoarthritis / Shuichi Matsuda, Hiromasa Miura, Yukihide Iwamoto -- Section VI. Nonpharmacologic interventions -- 36. Physical exercise for osteoarthritis of the knee: main modality of treatment and possible use for prevention / Hisashi Kurosawa -- 37. Acupuncture for the treatment of arthritis / Hi-Joon Park, Hyangsook Lee -- 38. Rehabilitative strategies for arthritis: physical, agents, exercise, and prosthesis therapies / Nobuyuki Kawate, Mitsumasa Yoda, Naomi Yoshioka, Masazumi Mizuma -- 39. Rehabilitation for arthritis: daily life guidelines / Fumihito Kasai, Masazumi Mizuma -- Section VII. Commentary -- 40. Arthritis, aging society, exercise, nutrition, and other precautionary measures / Siba P. Raychaudhuri, Hiroyoshi Moriyama, Debasis Bagchi.
  • 2014 Springer Protocols
    edited by Shunichi Shiozawa.
    Intravital Multiphoton Microscopy for Dissecting Cellular Dynamics in Arthritic Inflammation and Bone Destruction -- Monitoring Multifunctionality of Immune-Exhausted CD8 T in Cancer Patients -- Characterization of Innate Immune Signalings Stimulated by Ligands for Pattern Recognition Receptors -- Principled for the Use of in vivo Transgene Techniques: Overview and an Introductory Practical Guide for the Selection of Tetracycline-Controlled Transgenic Mice -- Unraveling Autoimmunity with the Adoptive Transfer of T Cells from TCR-Transgenic Mice -- In Vivo Cell Transfer Assay to Detect Autoreactive T Cell Subsets -- Characterization of microRNAs and Their Targets -- Studies on the T Cell Receptor (TCR) Revision of Autoantibody-Inducing CD4T (aiCD4 T) Cell -- Basic Techniques for Studies of iNKT Cells and MAIT Cells -- Induction of de novo Autoimmune Disease in Normal Mice Upon Repeated Immunization with Antigen -- Mouse Models of Experimental Dermal Fibrosis: The Bleomycin-Induced Dermal Fibrosis -- Screening for Novel Serum Biomarker for Monitoring Disease Activity in Rheumatoid Arthritis Using iTRAQ Technology Based Quantitative Proteomic Approach -- Genome-Wide Genetic Study in Autoimmune Disease Prone Mice -- Bayesian Systems-Based Genetic Association Analysis with Effect Strength Estimation and Omic Wide Interpretation: A Case Study in Rheumatoid Arthritis -- Sample Processing, Protocol and Statistical Analysis of the Time of Flight Secondary Ion Mass Spectrometry (ToF-SIMS) of Protein, Cell and Tissue Samples -- Label-Free Imaging of Adipogenesis by Coherent Anti-Stokes Raman Scattering Microscopy.
  • v. 1-2, 2007 Springer Protocols
    v. 2, 2007 Springer Protocols
    edited by Andrew P. Cope.
  • 2005 Springer
    edited by Parviz Kambin.
    From cauterization to arthroscopic and endoscopic spine surgery / Parviz Kambin -- Arthroscopic and endoscopic anatomy of the lumbar spine / Parviz Kambin -- Instruments and surgical approaches for minimally invasive spinal surgery via a posterolateral access / Parviz Kambin -- Herniated lumbar disc and lumbar radiculopathy / Parviz Kambin -- Management of discogenic pain and spinal instability using minimally invasive surgical techniques / Parviz Kambin -- Lateral recess stenosis of the lumbar spine foraminoplasty / Parviz Kambin -- The role of the epidural and radicular veins in chronic back pain and radiculopathy / Wesley W. Parke -- Diagnostic and therapeutic percutaneous transpedicular approaches to the spine / Alexander G. Hadjipavlou ... [et al.] -- Selective endoscopic discectomy : twelve years experience / Anthony T. Yeung -- Minimally invasive posterior fusion and internal fixation with ATAVI system / Richard D. Guyer and Terry P. Corbin -- Vertebral augmentation for osteoporotic compression fractures / Isador H. Lieberman and Daisuke Toga -- Principles of transthoracic, transperitoneal, and retroperitoneal endoscopic techniques to the thoracic and lumbar spine / Geoffrey M. McCullen and Hansen A. Yuan -- Use of the laser in minimally invasive spinal surgery and pain management / John C. Chiu and Martin H. Savitz -- Minimally invasive techniques in pain management / James Reynolds and Garrett Kine -- Experience with minimally invasive nucleus replacement / Michele Marcolongo ... [et al.] -- Interspinous process implant for the treatment of lateral and central spinal stenosis : operative technique and results / Douglas Wardlaw -- Frameless stereotactic imaging techniques in minimally invasive spine surgery / Alexander R. Vaccaro, Kern Singh, and Laurence N. Fitzhenry -- The rise and the fall of chemonucleolysis / James W. Simmons, Jr. and Robert D. Fraser -- Lumbar microendoscopic discectomy / Trent L. Tredway and Richard Fessler.
  • 2010 Springer
    Francisco del Piñal, editor ; Christophe Mathoulin, Riccardo Luchetti, co-editors.
    Arthroscopic Management of DRUJ Instability Following TFCC Ulnar Tears / Andrea Atzei -- Radial Side Tear of the Triangular Fibrocartilage Complex / Toshiyasu Nakamura -- Arthroscopic Management of Scapholunate Dissociation / Tommy Lindau -- Lunotriquetral and Extrinsic Ligaments Lesions Associated with Distal Radius Fractures / Didier Fontès -- Management of Concomitant Scaphoid Fractures / Christophe Mathoulin -- Perilunate Dislocations and Fracture Dislocations/Radiocarpal Dislocations and Fracture Dislocations / Mark Henry -- The Role of Arthroscopy in Postfracture Stiffness / Riccardo Luchetti -- Treatment of the Associated Ulnar-Sided Problems / Pier Paolo Borelli and Riccardo Luchetti -- Arthroscopic-Assisted Osteotomy for Intraarticular Malunion of the Distal Radius / Francisco del Piñal -- The Role of Arthroscopic Arthrodesis and Minimal Invasive Surgery in the Salvage of the Arthritic Wrist : Midcarpal Joint / Joseph F. Slade -- Arthroscopic Radiocarpal Fusion for Post-Traumatic Radiocarpal Arthrosis / Ho Pak-Cheong.
  • 2012 Springer
    Francisco del Piñal (editor in chief) ; Christophe Mathoulin and Toshiyasu Nakamura (co-editors).
  • 2016 Springer
    Piero Volpi, editor.
    This book describes the current applications of arthroscopy in a very wide range of sports injuries involving, among other sites, the hip, knee, ankle, shoulder, elbow, and wrist. For each condition, mechanisms of injury are explained and the role of arthroscopy in diagnosis and treatment is described. Relevant information is also provided on the epidemiology and mechanisms of injury in specific sports and on indications for treatment and rehabilitation. The book fully reflects the recent advances that have taken place in arthroscopy, permitting more accurate assessment and more successful management of post-traumatic pathologies. Furthermore, it acknowledges that as a result of the increasing use of new technologies and biomaterials, there is now particular interest in techniques that promote biological healing of articular lesions and permit complete functional recovery. The authors are leading specialists in the field who have aimed to provide practitioners with the clear guidance that they require on the evaluation and treatment of injuries incurred during sporting activity.
  • 2013 CRCnetBASE
    Kyriacos A. Athanasiou, Eric M. Darling, Grayson D. DuRaine, Jerry C. Hu, A. Hari Reddi.
    Articular cartilage injuries, which are well known for their inability to heal, often degenerate inexplicably to disastrous impairment. Multitudes of treatments have been devised for this problem, but no satisfactory long-term solutions have been established. However, over the past two decades, the swift growth and development of new knowledge and technologies for cartilage formation, pathology and repair have been exciting and inspirational. Written by world-class experts, this book covers all the latest research and clinical applications related to cartilage tissue engineering. The text explores the role of nanotechnology and also provides extensive references at the end of each chapter. Articular cartilage injuries, which are well known for their inability to heal, often degenerate inexplicably to disastrous impairment. Multitudes of treatments have been devised for this problem, but no satisfactory long-term solutions have been established. However, over the past two decades, the swift growth and development of new knowledge and technologies for cartilage formation, pathology and repair have been exciting and inspirational. Written by world-class experts, this book covers all the latest research and clinical applications related to cartilage tissue engineering. The text explores the role of nanotechnology and also provides extensive references at the end of each chapter.
  • 2012 Springer
    E. Carlos Rodríguez-Merchán, editor.
    1. Regeneration of Articular Cartilage of the Knee: Basic Concepts / E. Carlos Rodríguez-Merchán and Hortensia De la Corte-García -- 2. Articular Cartilage Defects of the Knee: Diagnosis and Treatment / Michael Heim and Israel Dudkiewicz -- 3. Imaging Techniques of Articular Cartilage / Carmen Martín-Hervás -- 4. Refixation of Detached Fragments / Eduardo García-Rey -- 5. Debridement, Joint Lavage and Cartilage Shaving / Alonso Moreno-García -- 6. Drilling, Abrasion and Microfractures / José L. Leal-Helmling and Santiago Bello-Prats -- 7. Osteochondral Transplantation and Mosaicplasty / Julián Fernández-González -- 8. Autologous Chondrocyte Implantation / Primitivo Gómez-Cardero, E. Carlos Rodríguez-Merchán, and Ángel Martínez-Lloreda -- 9. Alignment Osteotomies / E. Carlos Rodríguez-Merchán and Hortensia De la Corte-García -- 10. Rehabilitation of Chondral Lesions of the Knee / Hortensia De la Corte-Rodríguez, Juan M. Román-Belmonte, and Hortensia De la Corte-García -- 11. Medical Treatment: Intra-Articular Injections of Hyaluronic Acid / E. Carlos Rodríguez-Merchán and Hortensia De la Corte-García.
  • 2005 Wiley
    edited by Ronald Breslow.
    Artificial enzymes / Ronald Breslow -- Vitamin B6 enzyme models / Lei Liu and Ronald Breslow -- Evolution of synthetic polymers with enzyme-like catalytic activities / Irving M. Klotz and Junghun Suh -- Mimicking enzymes with antibodies / Donald Hilvert -- Protein-based artificial enzymes / Ben Duckworth and Mark D. Distefano -- Artificial hydrolytic metalloenzymes / Jik Chin and Hae-Jo Kim -- Artificial restriction enzymes as tools for future molecular biology and biotechnology / Yoji Yamamoto and Makoto Komiyama.
  • 2008 Springer
    Peter J. Bentley, Doheon Lee, Sungwon Jung (eds.).
  • 2008 CRCnetBASE
    Deyi Li and Yi Du.
  • 2007 CRCnetBASE
    Mohsen Shahinpoor, Kwang J. Kim, Mehran Mojarrad.
  • 2008 Springer Protocols
    David J. Livingstone, editor.
    Artificial neural networks in biology and chemistry : the evolution of a new analytical tool / Hugh M. Cartwright -- Overview of artificial neural networks / Jinming Zou, Yi Han, and Sung-Sau So -- Bayesian regularization of neural networks / Frank Burden and Dave Winkler -- Kohonen and counterpropagation neural networks applied for mapping and interpretation of IR spectra / Marjana Novic -- Artificial neural network modeling in environmental toxicology / James Devillers -- Neural networks in analytical chemistry / Mehdi Jalali-Heravi -- Application of artificial neural networks for decision support in medicine / Brendan Larder, Dechao Wang, and Andy Revell -- Neural networks in building QSAR models / Igor I. Baskin, Vladimir A. Palyulin, and Nikolai S. Zefirov -- Peptide bioinformatics : peptide classification using peptide machines / Zheng Rong Yang -- Associative neural network / Igor V. Tetko -- Neural networks predict protein structure and function / Marco Punta and Burkhard Rost -- The extraction of information and knowledge from trained neural networks / David J. Livingstone ... [et al.].
  • 2008 Springer
    Lionel Prevost, Simone Marinai, Friedhelm Schwenker (eds.).
  • 2015 Springer Protocols
    edited by Hugh Cartwright.
    Introduction to the analysis of the intracellular sorting information in protein sequences: from molecular biology to artificial neural networks -- Protein structural information derived from NMR chemical shift with the neural network program TALOS-N -- Predicting bacterial community assemblages using an artificial neural network approach -- A general ANN-based multitasking model for the discovery of potent and safer antibacterial agents -- Use of artificial neural networks in the QSAR prediction of physicochemical properties and toxicities for REACH legislation -- Artificial neural network for charge prediction in metabolite identification by mass spectrometry -- Prediction of bioactive peptides using artificial neural networks -- AutoWeka: toward an automated data mining software for QSAR and QSPR studies -- Ligand biological activity predictions using fingerprint-based artificial neural networks (FANN-QSAR) -- GENN: a general neural network for learning tabulated data with examples from protein structure prediction -- Modulation of grasping force in prosthetic hands using neural network-based predictive control -- Application of artificial neural networks in computer-aided diagnosis -- Developing a multimodal biometric authentication system using soft computing methods -- Using neural networks to understand the information that guides behavior: a case study in visual navigation -- Jump neural network for real-time prediction of glucose concentration -- Preparation of Ta-O-based tunnel junctions to obtain artificial synapses based on memristive switching -- Architecture and biological applications of artificial neural networks: a tuberculosis perspective -- Neural networks and fuzzy clustering methods for assessing the efficacy of microarray based intrinsic gene signatures in breast cancer classification and the character and relations of identified subtypes -- QSAR/QSPR as an application of artificial neural networks -- Preface. Artificial neural networks.
  • 2008 Springer
    edited by Christopher Tollefsen.
    Why do unresponsive patients still matter? / Anthony Fisher -- Are we morally obliged to feed pvs patients till natural death? / Michael Degnan -- Caring for persons in the "persistent vegetative state" and Pope John Paul II's March 20 2004 address on "life-sustaining treatments and the vegetative state" / William E. May -- Food and fluids : human law, human rights and human interests / Jacqueline Laing -- Quality of life and assisted nutrition / Alfonso Gómez-Lobo -- Towards ethical guidelines for the use of artificial nutrition and hydration / Joseph Boyle -- Understanding the ethics of artificially providing food and water / J.L.A. Garcia -- The ethics of Pope John Paul II's allocution on care of the PVS patient : a response to J.L.A. Garcia / Peter J. Cataldo -- Reflections on the papal allocution concerning care for PVS patients / Kevin O'Rourke -- The papal allocution concerning care for PVS patients : a reply to Fr. O'Rourke / Patrick Lee -- Response to Patrick Lee / Kevin O'Rourke -- The morality of tube feeding PVS patients : a critique of the view of Kevin O'Rourke, O.P. / Mark S. Latkovic -- Ten errors regarding end of life issues, and especially artificial nutrition and hydration / Christopher Tollefsen.
  • 2009 Springer
    Nadey Hakim (ed.).
  • 2006
    Gerald E. Miller.
    Artificial heart valves -- Artificial heart and cardiac assist devices -- Cardiac pacemakers -- Dialysis.
  • 2005 Springer
    K. Kobayashi, E. Tsuchida, H. Horinouchi (eds.).
    Also available: Print – 2005
  • v. 1, 1969.
    by Emanuel J. Mickel, Jr.
    Status: Not Checked OutLane Catalog Record
    1. The Influence of opium and hashish on the literature of French Romanticism and Les fleurs du mal.
  • 2014 Springer Protocols
    edited by Atsushi Ogawa.
  • 2007 Springer
    Mark S. Humayun ... [et al.] (eds.).
  • 2009
    Michael F. Marmor and James G. Ravin.
    Status: Not Checked OutLane Catalog Record
  • 2005 Springer
    edited by Elliot Fratkin and Eric Abella Roth.
    Introduction : the social, health, and economic consequences of pastoral sedentarization in Marsabit District, Northern Kenya / Eric Abella Roth and Elliot Fratkin -- The setting : pastoral sedentarization in Marsabit District, Northern Kenya / Elliot Fratkin and Eric Abella Roth -- Time, terror, and pastoral inertia / John G. Galaty -- Ecological and economic consequences of reduced mobility in pastoral livestock production systems / H. Jürgen Schwarz -- Cursed if you do, cursed if you don't : the contradictory processes of pastoral sedentarization in Northern Kenya / John McPeak and Peter D. Little -- Once nomads settle : assessing the process, motives, and welfare changes of settlements on Mount Marsabit / Wario R. Adano and Karen Witsenburg -- From milk to maize : the transition to agriculture for Rendille and Ariaal pastoralists / Kevin Smith -- Women's changing economic roles with pastoral sedentarization / Elliot Fratkin and Kevin Smith -- The effects of pastoral sedentarization on children's growth and nutrition among Ariaal and Rendille in Northern Kenya / Eric Abella Roth, Martha A. Nathan, and Elliot Fratkin -- Health and morbidity among Rendille pastoralist children / Martha A. Nathan ... [et al.] -- Sedentarization and seasonality : maternal dietary and health consequences in Ariaal and Rendille communities in Northern Kenya / Masako Fujita ... [et al.] -- Development, modernization, and medicalization : influences on the changing nature of female "circumcision" in Rendille society / Bettina Shell-Duncan, Walter Obungu Obiero, and Leunita Auko Muruli -- Female education in a sedentary Ariaal Rendille community / Eric Abella Roth and Elizabeth N. Ngugi.
  • 2014
    senior editor, Richard K. Ries ; associate editors, David A. Fiellin, Shannon C. Miller, Richard Saitz
    Status: Not Checked OutLane Catalog Record
    Section 1. Basic Science and Core Concepts : -- 1. Drug Addiction: The Neurobiology of Behavior Gone Awry -- 2. The Epidemiology of Substance Use Disorders -- 3. The Anatomy of Addiction -- 4. From Neurobiology to Treatment: Progress Against Addiction -- 5. Understanding "Behavioral Addictions": Insights from Research -- -- Section 2. Pharmacology : -- 6. Pharmacokinetic and Pharmacodynamic Principles -- 7. The Pharmacology of Alcohol -- 8. The Pharmacology of Nonalcohol Sedative Hypnotics -- 9. The Pharmacology of Opioids -- 10. The Pharmacology of Cocaine, Amphetamines, and Other Stimulants -- 11. The Pharmacology of Caffeine -- 12. The Pharmacology of Nicotine and Tobacco -- 13. The Pharmacology of Marijuana -- 14. The Pharmacology of Hallucinogens -- 15. The Pharmacology of Dissociatives -- 16. The Pharmacology of Inhalants -- 17. The Pharmacology of Anabolic-Androgenic Steroids -- -- Section 3. Diagnosis, Assessment, and Early Intervention : -- 18. Screening and Brief Intervention -- 19. Laboratory Diagnosis -- 20. Assessment -- 21. Environmental Approaches to Prevention: A Community-Based Perspective -- -- Section 4. Overview of Addiction Treatment : -- 22. Addiction Medicine in America: Its Birth and Early History (1750-1935) with a Modern Postscript -- 23. Treatment of Heavy Drinking and Alcohol Use Disorder -- 24. The Treatment of Drug Addiction: An Overview -- 25. Moving Toward Integrated Care for Substance Use Disorders: Lessons from History and the Rest of Health Care -- 26. Effects of Treatment Setting, Duration, and Amount on Patient Outcomes -- 27. The ASAM Criteria and Matching Patients to Treatment -- 28. Linking Addiction Treatment with Other Medical and Psychiatric Treatment Systems -- 29. Alternative Therapies for Alcohol and Drug Addiction -- 30. The Harm Reduction Approach to Prevention and Treatment -- 31. Quality Improvement for Addiction Treatment -- 32. Nursing Roles in Addressing Addiction -- 33. International Perspectives on Addiction Management -- -- Section 5. Special Issues in Addiction : -- 34. Nonmedical Use, Misuse, and Abuse of Prescription Medications -- 35. Special Issues in Treatment: Women -- 36. Treatment of Older Adults -- 37. Cultural Issues in Addiction Medicine -- 38. College Student Drinking -- 39. Pathologic Gambling: Clinical -- 40. Sexual Addiction -- 41. Physician Health Programs and Addiction among Physicians -- -- Section 6. Management of Intoxication and Withdrawal : -- 42. Management of Intoxication and -- 43. Management of Alcohol Intoxication and Withdrawal -- 44. Management of Sedative-Hypnotic Intoxication and Withdrawal -- 45. Management of Opioid Intoxication and Withdrawal -- 46. Management of Stimulant, Hallucinogen, Marijuana, Phencyclidine, and Club Drug Intoxication and Withdrawal -- -- Section 7. Pharmacologic Interventions : -- 47. Medications for Use in Alcohol -- 48. Pharmacologic Intervention for Sedative-Hypnotic Addiction -- 49. Pharmacologic Interventions for Opioid Dependence -- 50. Opioid Maintenance Treatment -- 51. Special Issues in Office-Based Opioid Treatment -- 52. Pharmacologic Interventions for Cocaine, Methamphetamine, and Other Stimulant Addiction -- 53. Pharmacologic Interventions for Tobacco Dependence -- 54. Pharmacologic Interventions for Other Drug and Multiple Drug Addictions -- -- Section 8. Behavioral Interventions : -- 55. Enhancing Motivation to Change -- 56. Group Therapies -- 57. Individual Treatment -- 58. Contingency Management and the Community Reinforcement Approach -- 59. Behavioral Interventions in Smoking Cessation -- 60. Network Therapy -- 61. Therapeutic Communities -- 62. Aversion Therapies -- 63. Family Involvement in Addiction, Treatment, and Recovery -- 64. Twelve-Step Facilitation Approaches -- 65. Microprocessor Abuse and Internet Addiction -- 66. Relapse Prevention: Clinical Models and Intervention Strategies -- 67. Medical Management Techniques and Collaborative Care: Integrating Behavioral with Pharmacologic Interventions in Addiction Treatment -- 68. Conceptual and Treatment Issues in "Behavioral Addictions" -- -- Section 9. Mutual Help, Twelve Step, and Other Recovery Programs : -- 69. Twelve-Step Programs in Addiction Recovery -- 70. Recent Research into Twelve-Step Programs -- 71. Spirituality in the Recovery Process -- -- Section 10. Medical Disorders and Complications of Addiction : -- 72. Medical and Surgical Complications of Addiction -- 73. Cardiovascular Consequences of Alcohol and Other Drug Use -- 74. Liver Disorders Related to Alcohol and Other Drug Use -- 75. Renal and Metabolic Disorders Related to Alcohol and Other Drug Use -- 76. Gastrointestinal Disorders Related to Alcohol and Other Drug Use -- 77. Respiratory Tract Disorders Related to Alcohol and Other Drug Use -- 78. Neurologic Disorders Related to Alcohol and Other Drug Use -- 79. Human Immunodeficiency Virus, Tuberculosis, and Other Infectious Diseases Related to Alcohol and Other Drug Use -- 80. Sleep Disorders Related to Alcohol and Other Drug Use -- 81. Traumatic Injuries Related to Alcohol and Other Drug Use: Epidemiology, Screening, and Prevention -- 82. Endocrine and Reproductive Disorders Related to Alcohol and Other Drug Use -- 83. Alcohol and Other Drug Use during Pregnancy: Management of the Mother and Child -- 84. Surgical Interventions in the Alcohol- or Drug-Using Patient -- -- Section 11. Co-Occurring Addiction and Psychiatric Disorders : -- 85. Substance-Induced Mental Disorders -- 86. Co-Occurring Addictive and Mood Disorders -- 87. Co-Occurring Addiction and Anxiety Disorders -- 88. Co-Occurring Addiction and Psychotic Disorders -- 89. Co-Occurring Addictive Disorder and Attention Deficit Hyperactivity Disorder -- 90. Co-Occurring Personality Disorders and Addiction -- 91. Posttraumatic Stress Disorder and Substance Use Disorder Comorbidity -- 92. Co-Occurring Addiction and Eating Disorders -- -- Section 12. Pain and Addiction : -- 93. The Pathophysiology of Chronic Pain and Clinical Interfaces with Addiction -- 94. Psychological Issues in the Management of Pain -- 95. Rehabilitation Approaches to Pain Management -- 96. Nonopioid Pharmacotherapy of Pain -- 97. Opioid Therapy of Pain -- 98. Comorbid Pain and Addiction -- 99. Legal and Regulatory Considerations in Opioid Prescribing -- -- Section 13. Children and Adolescents : -- 100. Epidemiology of Adolescent Substance Use -- 101. Preventing Substance Use among Children and Adolescents -- 102. Neurobiology of Addiction from a Developmental Perspective -- 103. Screening and Brief Intervention for Adolescents -- 104. Assessing Adolescent Substance Use -- 105. Placement Criteria and Strategies for Adolescent Treatment Matching -- 106. Adolescent Treatment and Relapse Prevention -- 107. Pharmacotherapy for Adolescents with Substance Use Disorders -- 108. Co-Occurring Psychiatric Disorders in Adolescents -- -- Section 14. Ethical, Legal, and Liability Issues in Addiction Practice : -- 109. Ethical Issues in Addiction Practice -- 110. Consent and Confidentiality Issues in Addiction Practice -- 111. Clinical, Ethical, and Legal Considerations in Prescribing Drugs with Abuse Potential -- 112. The Science and Clinical Uses of Drug Testing -- 113. Drug Treatment Courts and the Treatment of Persons in the Criminal Justice System -- 114. Preventing and Treating Substance Use Disorders in Military Personnel.
  • 2005 CRCnetBASE
    edited by Ronald F. Dodson, Samuel P. Hammar.
  • OHR
  • 2013 ScienceDirect
    edited by Celia Holland.
    This book tackles a number of different perspectives concerning the parasitic helminth Ascaris, both in animals and in humans and the disease known as ascariasis. It seeks to identify interesting, exciting and novel aspects, which will interest readers from a broad range of disciplines. Over a quarter of the world's population are infected with the human roundworm, and the equivalent in pigs is equally ubiquitous. Both contribute to insidious and chronic nutritional morbidity, and this has been quantified, in humans, as disability adjusted life years approximating 10.5 million. Ascaris larvae develop in host parenteral tissues, and the resultant pathology has been condemnation. Ascariasis, despite its staggering global prevalence and the sheer numbers of people it infects, remains a classic neglected disease. However, renewed interest in the consequences of early infection with worms from the perspective of immune modulation, co-infections and the development of allergy further enhances the relevance of these parasites. Brings together a wide range of topics and approaches and recent, comprehensive and progressive research concerning the neglected parasite Ascaris Provides a blueprint of how a single parasite entity can stimulate interest in basic biology, clinical science, veterinary science, public health and epidemiology Presents a wealth of new insights given that a book on this parasite has not been published for over 20 years 16 chapters from a range of top authors from around the world.
  • 2011 Karger
    volume editor, Alexander L. Gerbes Munich.
    Differential diagnosis of ascites / Appenrodt, B. -- Current treatment strategies : diuretics / Bernardi, M. -- Paracentesis / Sanyal, A.J., Bajaj, J.S., Shaw, J. -- Large volume paracentesis : which plasma expander? / Terg, R.A -- Albumin : not just a plasma expander / Davies, N.A. ... [et al.] -- Transjugular intrahepatic portosystemic shunt for ascites : which patients will benefit? / Salerno, F., Cazzaniga, M. -- Spontaneous bacterial peritonitis prophylaxis and treatment / Wiest, R., Garcia-Tsao, G. -- Clinical implications of hyponatremia in cirrhosis / Heuman, D.M. -- Vaptans for ascites : chances and risks / Wong, F. -- Cardiorenal syndrome : a new entity? / Moller, S., Krag, A. -- Renal failure in cirrhosis / Gustot, T., Moreau, R. -- Novel definition of hepatorenal syndrome : clinical consequences / Fernandez, J., Arroyo, V. -- Role of infections in hepatorenal syndrome / Wiest, R. -- Tips for HRS / Sauerbruch, T., Appenrodt, B. -- Vasoconstrictor therapy for hepatorenal syndrome / Yeo, C.-M.; Garcia-Tsao, G. -- Terlipressin for hepatorenal syndrome : the US experience / Musana, A.K., Sanyal, A.J. -- Terlipressin for hepatorenal syndrome : predictors of response / Cárdenas, A., Gines, P. -- Safety of terlipressin for hepatorenal syndrome / Krag, A., Moller, S. -- Terlipressin for hepatorenal syndrome : novel strategies and future perspectives / Angeli, P. --Hepatorenal syndrome and liver transplantation / Gonwa, T.A.
  • 2014 Springer
    David E. Beck... [and others], editors.
    The ASCRS Manual of Colon and Rectal Surgery, Second Edition is designed to provide a rapid access pocket reference for residents, fellows, private clinicians, and allied health professionals caring for patients with colorectal surgical diseases. The Manual, abstracted from the ASCRS Textbook of Colon and Rectal Surgery, Second Edition, is intended to impart succinct, clinically relevant information for daily patient care. The chapters take an evidence-based approach and many provide ASCRS practice parameters. The contents are presented consistently, with concise overviews of the most clinically relevant topics. The disease chapters discuss etiology, anatomic considerations, patient evaluation, lab results, imaging, diagnosis and treatment. The surgical chapters address these same issues, in addition to discussion of minimally invasive versus open techniques, possible complications, and perioperative care. The Manual also includes anatomical and technique drawings, operative photos and algorithms. Concise yet comprehensive, The ASCRS Manual of Colon and Rectal Surgery, Second Edition is very useful for physicians and researchers dealing with diseases of the colon and rectum.
  • 2009 Springer
    [edited by] David E. Beck, Patricia L. Roberts, John L. Rombeau, Michael J. Stamos, Steven D. Wexner.
  • 2011 Springer
    editors, David E. Beck, Patricia L. Roberts, Theodore J. Saclarides, Anthony J. Senagore, Michael J. Stamos, Steven D. Wexner.
    This is the first official textbook of the American Society of Colon and Rectal Surgeons (ASCRS) (www.fascrs.org) that adheres to the principals of evidence-based practice and utilizes ASCRS practice parameters. Written by top experts in the specialty, each chapter correlates with the core curriculum developed by the Program Director's Association in Colorectal Surgery. Chapters include Anatomy, Physiology, Genetics, Diagnostic Evaluation, and Perioperative Management.
  • 2007 Springer
    senior editors, Bruce G. Wolff ... [et al.] ; associate editors, James M. Church ... [et al.].
  • 2016 Springer
    editors: Scott R. Steele, Tracy L. Hull, Thomas E. Read, Theodore J. Saclarides, Anthony J. Senagore, Charles B. Whitlow.
    Anatomy and Embryology of the Colon, Rectum & Anus -- Colonic Physiology -- Anal Physiology: The physiology of continence and defecation -- Endoscopy -- Endoscopic management of polyps, polypectomy and combined endoscopic and laparoscopic surgery -- Preoperative assessment of colorectal patients -- Optimizing Outcomes with Enhanced Recovery -- Postoperative Complications -- Anastomotic Construction -- Anastomotic complications -- Approach to Anal Pain -- Hemorrhoids -- Anal Fissure -- Anorectal Abscess and Fistula -- Complex Anorectal Fistulas -- Rectovaginal Fistula -- Pilonidal Disease and Hidradenitis Suppurativa -- Dermatology and Pruritus Ani -- Sexually Transmitted Infections -- Anal Intraepithelial Neoplasia -- Anal Cancer -- Presacral Tumors -- Molecular Basis of Colorectal Cancer and Overview of Inherited Colorectal Cancer Syndromes -- Colorectal Neoplasms: Screening and Surveillance after Polypectomy -- Colon Cancer: Preoperative Evaluation and Staging -- The Surgical Management of Colon Cancer -- Rectal Cancer: Preoperative Evaluation and Staging -- Rectal Cancer: Neoadjuvant Therapy -- Local excision of rectal neoplasia -- Rectal Cancer: Watch and Wait -- Proctectomy -- Rectal Cancer Decision Making -- Colorectal Cancer: Postoperative Adjuvant Therapy -- Colorectal Cancer: Surveillance after Curative-Intent Therapy -- Colorectal Cancer: Management of Local Recurrence -- Colorectal Cancer: Management of Stage IV Disease -- Appendiceal Neoplasms -- Carcinoids, GISTs and Lymphomas of Colon and Rectum -- Diverticular Disease -- Large Bowel Obstruction -- Lower Gastrointestinal Hemorrhage -- Endometriosis -- Trauma of the Colon, Rectum, and Anus -- Inflammatory Bowel Disease: Pathobiology -- IBD Diagnosis and Evaluation -- Medical Management of Chronic Ulcerative Colitis -- Medical Management of Crohn's Disease -- Anorectal Crohn's disease -- Crohn's Disease: Surgical Management -- Ulcerative Colitis -- Surgical Management -- Complications of the Ileal Pouch -- Infectious Colitides -- Clostridium difficile Infection -- Radiation, microscopic, ischemic colitis -- Intestinal Stomas -- Functional complications after colon and rectal surgery -- Common Tests for the Pelvic Floor -- Evaluation of Constipation and Treatment of Abdominal Constipation -- Obstructed Defecation -- Rectal Prolapse -- Evaluation and Treatment of FI -- Functional Bowel Disorders for the Colorectal Surgeon -- Middle and Anterior Compartment: Issues for the Colorectal Surgeon -- Pediatric Colorectal Disorders -- Considerations for Geriatric Patients Undergoing Colorectal Surgery -- Health Care Economics -- Ethical Issues in Colorectal Surgery -- Welcome to Litigation -- Surgical Education -- Maintenance of Certification: Current Status and Future Considerations -- Quality & Safety in Colon & Rectal Surgery -- Practice Management.
  • 2016 ClinicalKey
    [edited by] Roberto M. Lang, Steven A. Goldstein, Itzhak Kronzon, Bijoy K. Khandheria, Victor Mor-Avi.
    Written and endorsed by world experts from the American Society of Echocardiography (ASE), this unique multimedia resource uses text, case studies, and online components to cover the latest uses of echocardiography, including the most recent 2D and 3D advances. Unlike other existing textbooks in echocardiography, including the predecessor of this volume, entitled Dynamic Echocardiography, this 2nd edition, with its new title, covers a full range of topics, reflected in its 200 chapters that include essential material in a succinct format. Dr. Roberto M. Lang and his expert colleagues provide everything you need to assess cardiac anatomy and function and obtain clinically useful, noninvasive information for more accurate diagnosis and evaluation of heart disease.
  • 2014 ClinicalKey
    [edited by] George W. Holcomb III, J. Patrick Murphy and Daniel J. Ostlie.
    Acclaimed for its unsurpassed readability and manageable scope, Ashcraft's Pediatric Surgery presents authoritative, practical guidance on treating the entire range of general surgical and urological problems in infants, children, and adolescents. State-of-the-art, expert coverage equips you to implement all the latest approaches and achieve optimal outcomes for all of your patients. Make the most effective use of today's best open and minimally invasive techniques, including single-site umbilical laparoscopic surgery, with guidance from internationally recognized experts in the field. Focus on evidence-based treatments and outcomes to apply today's best practices.
  • 2010
    [edited by] George Whitfield Holcomb III, J. Patrick Murphy ; associate editor, Daniel J. Ostlie.
    Status: Not Checked OutLane Catalog Record
    Physiology of the newborn -- Nutritional support of the pediatric patient -- Anesthetic considerations -- Renal impairment -- Coagulopathies and sickle cell disease -- Extracorporeal membrane oxygenation -- Mechanical ventilation in pediatric surgical disease -- Vascular access -- Surgical infectious disease -- Fetal therapy -- Foreign bodies -- Bites -- Burns -- Early assessment and management of trauma -- Thoracic trauma -- Abdominal and renal trauma -- Pediatric head trauma -- Pediatric orthopedic trauma -- Neurosurgical conditions -- Congenital chest wall deformities -- Tracheal obstruction and repair -- Congenital bronchopulmonary malformations -- Acquired lesions of the lung and pleura -- Congenital diaphragmatic hernia and eventration -- Mediastinal tumors -- The esophagus -- Esophageal atresia and tracheoesophageal malformations -- Thoracoscopy in infants and children -- Gastroesophageal reflux -- Lesions of the stomach -- Duodenal and intestinal atresia and stenosis -- Malrotation -- Meconium disease -- Necrotizing enterocolitis -- Hirschsprung's disease -- Imperforate anus and cloacal malformations -- Fecal incontinence and constipation -- Acquired anorectal disorders -- Intussusception -- Alimentary tract duplications -- Meckel's diverticulum -- Inflammatory bowel disease and intestinal cancer -- Appendicitis -- Biliary tract disorders and portal hypertension -- Solid organ and intestinal transplantation -- Lesions of the pancreas -- Splenic conditions -- Congenital abdominal wall defects -- Umbilical and other abdominal wall hernias -- Laparoscopy -- Inguinal hernias and hydroceles -- Undescended testes and testicular tumors -- The acute scrotum -- Developmental and positional anomalies of the kidneys -- Ureteral obstruction and malformations -- Urinary tract infection and vesicoureteral reflux -- Bladder and urethra -- Posterior urethral valves -- Bladder and cloacal exstrophy -- Hypospadias -- Circumcision -- Prune-belly syndrome -- Disorders of sexual differentiation -- Urologic laparoscopy -- Renovascular hypertension -- Principles of adjuvant therapy in childhood cancer -- Renal tumors -- Neuroblastoma -- Lesions of the liver -- Teratomas, dermoids, and other soft tissue tumors -- Lymphomas -- Rhabdomyosarcoma -- Nevus and melanoma -- Vascular anomalies -- Head and neck sinuses and masses -- Pediatric and adolescent gynecology -- Breast diseases -- Endocrine disorders and tumors -- Bariatric surgical procedures in adolescence -- Evidence-based medicine.
  • 2016 ClinicalKey
    William Pai-Dei Chen.
    Machine generated contents note: 1.What Is an Upper Lid Crease? -- 2.Historical Considerations -- 3.Comparative Anatomy of the Eyelids -- 4.The Eyelid Crease: Goals and Benchmarks -- 5.Consultation and Counseling -- 6.Suture Ligation Methods -- 7.External Incision Methods -- 8.Asian Blepharoplasty I: The First Vector -- 9.Asian Blepharoplasty II: The Second Vector -- 10.Asian Blepharoplasty III: Factors that Influence Outcome -- 11.Concept of Triangular, Trapezoidal and Rectangular Debulkting -- Application in Upper Blepharoplasty -- 12.Optimal Closure and Management of Wound Healing -- 13.Primary Asian Blepharoplasty Results (Before and After) -- 14.Suboptimal Factors -- 15.Revision Parameters -- 16.Revisions in Suboptimal Cases -- 17.Advanced Concept of a Glide Zone as It Relates to Upper Lid Crease, Lid Fold and Application in Asian Blepharoplasty -- 18.Advanced: Beveled Approach and Mid-Lamellar Clearance in Revisional Asian Blepharoplasty -- 19.Advanced: Angle of Observation, Crease Height and Its Effects on Clinical Outcome of Upper Blepharoplasty -- 20.Advanced: The Concept of Tarsal Tilt -- Its Effects in Normal and Abnormal Clinical Conditions -- 21.Advanced: Effect of High Anchoring of the Crease, Faden-like Effect and Use of Buried Sutures -- 22.Advanced: Summary of Eyelid Crease Factors -- 23.Advanced Concept of the Eyelid Crease as a Stringed Series of Unipoints -- 24.Asian Eyelid Surgery: My Thoughts / Khoo Boo-Chai -- 25.Treatment of Medial Upper Lid Fold and the Fog Surrounding Epicanthoplasty -- 26.Novel Technique, Challenges and Outlook for the Future in Aesthetic Surgery of the Asian Eyelid.
  • 2005 CRCnetBASE
    John Shi, Chi-Tang Ho, and Fereidoon Shahidi.
    1. Functional Foods and Their Impact on Nutrition and Health: Opportunities in the Asia Pacific / Mark L. Wahlqvist and Naiyana Wattanapenpaiboon -- 2. Asian Herbal Products: The Basis for Development of High-Quality Dietary Supplements and New Medicines / Kuo-Hsiung Lee, Hideji Itokawa, and Mutsuo Kozuka -- 3. Chemistry, Pharmacology, and Quality Control of Selected Popular Asian Herbs in the U.S. Market / Mingfu Wang, Qing-Li Wu, James E. Simon, Yi Jin, and Chi-Tang Ho -- 4. Health-Related Fat Replacers Prepared from Grain for Improving Functional and Nutritive Values of Asian Foods / George E. Inglett, Craig J. Carriere, and Saipin Maneepun -- 5. Antiaging Properties of Asian Functional Foods: A Historical Topic Closely Linked to Longevity / Yi Dang -- 6. A New Treatment and Prevention Strategy for Human Papillomaviruses / Karen J. Auborn -- 7. Traditional Functional Foods in Korea / Su-Rae Lee -- 8. Evolution of Korean Dietary Culture and Health Food Concepts / Cherl-Ho Lee and Tai-Wan Kwon -- 9. Asian Fish Sauce as a Source of Nutrition / Chaufah Thongthai and Asbjørn Gildberg -- 10. Nutraceuticals from Seafood and Seafood By-Products / Fereidoon Shahidi -- 11. Functional Foods from Meat Animals / Youling L. Xiong -- 12. Functional Foods from Fruit and Fruit Products / John Shi and James H. Moy -- 13. Functional Foods from Fermented Vegetable Products: Kimchi (Korean Fermented Vegetables) and Functionality / Kun-Young Park and Sook-Hee Rhee -- 14. Antioxidative Function of Seeds and Nuts and Their Traditional Oils in the Orient / Yasuko Fukuda and Mayumi Nagashima -- 15. Antioxidants and Other Functional Extracts from Sugarcane / Kenji Koge, Michael Saska, and Chung Chi Chou -- 16. Functional Foods from Garlic and Onion / Toyohiko Ariga and Taiichiro Seki -- 17. Functional Foods from Date Fruits / Jiwan S. Sidhu and Suad N. Al-Hooti -- 18. Functional Foods and Products from Japanese Green Tea / Teruo Miyazawa and Kiyotaka Nakagawa -- 19. Miso as a Functional Food / W.J. Mullin -- 20. Fermented Soybean Products as Functional Foods: Functional Properties of Doenjang (Fermented Soybean Paste) / Kun-Young Park and Keun-Ok Jung -- 21. Conventional and Emerging Food Processing Technologies for Asian Functional Food Production / Hao Feng and Scott A. Morris.
  • 2014 Springer
    AKM Ahsan Ullah, Ahmed Shafiqul Huque.
    This book explores a number of issues related to the stigma arising from HIV/AIDS infection, perceived or actual discrimination from the community and society, and the extent of vulnerabilities for infected Asian refugees and immigrants. It assesses the health care and treatment regimen for HIV/AIDS accessed by immigrants and refugee claimants in North America, including treatments offered by the health-care system and ethnic communities, and their perceptions and biases relating to HIV/AIDS issues. On another level, the book identifies the ways in which HIV-sufferer immigrants and refugees/refugee claimants from Asia are vulnerable to discrimination due to 1) lack of information about HIV/AIDS incidence in the community; 2) inability of the health system to respond appropriately; and 3) the community{u2019}s need for introspection on their own health issues. This book reveals the dynamics that influence choice, behavior, and lifestyle of HIV sufferer immigrants, adds to the existing knowledge about refugees and migrants, and proposes a unified theory of discrimination and stigmatization within the context of human rights. In addition, the book presents a number of policy recommendations based on empirical findings with a view to helping reshape polices regarding refugee HIV sufferers and their social ramifications. This book will be of interest to researchers and students in any field from social sciences, health and psychology, as well as practitioners in the field of development and public policy. The book will be beneficial to policy formulators and implementers engaged in addressing the serious threat emanating from the HIV/AIDS pandemic.
  • 2011 Springer
    Takashi Muto, Toshitaka Nakahara, Eun Woo Name, editors.
    Asian ideas on health promotion and education from historical perspectives of the theory of yojo as an interface of health, self, and society -- Developing the curriculum and instruction model for suicide prevention and life education in Taiwan -- The yogo teacher, the health room, and health education at school in Japan -- New strategy on prevention and control of noncommunicable lifestyle-related diseases focusing on metablic syndrome in Japan -- Sensory awakening as a new approach to health promotion -- Health promotion and education in Thailand in comparison with the Japanese health care system and health informatics -- Development of a robot-assisted activity program for elderly people incorporating reading aloud and arithmetic calculation -- Health promotion for cancer survivors: new paradigm beyond prevention and treatment -- Alternative medicine and health promotion -- Key players in health promotion policy in the Northern part of the Western Pacific -- Community-based participatory research: a promising approach to address social determinants of health -- Toward development of intervention methods for strengthening the sense of coherence: suggestions from Japan -- Social capital and population approach -- Health promotion and healthy city projects in Korea -- A network of healthy cities in Asia and the Pacific: the alliance for healthy cities -- Empowerment in health and community settings -- Health communications -- Cost-benefit of health promotion: will it pay off?: Japan's venture against metabolic syndrome -- Health promotion activity and outcomes in the community -- Japan's current health issues and health promotion in the community setting: focus on public health nurses' activities -- Outcomes of lifestyle improvement programs in the last ten years in Asia -- Health promoting schools in Taiwan: present status and future perspectives -- Workplace health promotion in Korea -- Characteristics of workplace health promotion in Japan -- Tokyo gas health promotion program -- Evidence of physical activity for disease control and health promotion -- Using computer-tailored technology to promote physical activity and healthy eating: a review of the literature and Asian-Pacific evidence -- Dietary lifestyle interventions of energy restriction for weight control and salt reduction for prevention of hypertensive risk in Asian adults -- Building capacity in smoking cessation counseling among health care professionals in China -- Issues of Korean alcohol policy perspectives -- Current status and prevention of obesity -- Waist-to-height ratio is the best anthropometric index for screening the risk of obesity-related disorders -- Health promotion and education based on the features of cardiovascular disease in Asia -- Prevention and psychological intervention in depression and stress-related conditions -- Principles and activities of oral health promotion in Asian countries -- New development in education to prevent sexual transmitted infections, especially HIV/AIDS: actual practice of sexuality health education by means of peer counseling approach -- School-based safety promotion in Japan -- "Safe community" in Asia: safety promotion based on injury prevention.
  • 2015 Springer
    Ninh T. Nguyen, Robin P. Blackstone, John M. Morton, Jaime Ponce, Raul J. Rosenthal, editors.
    Developed by the American Society for Metabolic and Bariatric Surgery (ASMBS), The ASMBS Textbook of Bariatric Surgery provides a comprehensive guide of information dealing with the ever evolving field of bariatric surgery. Volume 1: Bariatric Surgery covers the basic considerations for bariatric surgery, the currently accepted procedures, outcomes of bariatric surgery including longterm weight loss, improvement and resolution of comorbidities, and improvement in quality of life. A section focuses on revisional bariatric surgery and new innovative endoscopic bariatric procedures. Special emphasis is also given to the topics of metabolic surgery and surgery for patients with lower BMI (30-35). The ASMBS Textbook of Bariatric Surgery, Volume 1: Bariatric Surgery is of great value to surgeons, residents and fellows, bariatric physicians, psychologists, psychiatrists, and integrated health members that manage the morbidly obese.
  • 2014 Springer
    Christopher Still, David B. Sarwer, Jeanne Blankenship, editors.
    Developed by the American Society for Metabolic and Bariatric Surgery (ASMBS), The ASMBS Textbook of Bariatric Surgery provides a comprehensive guide of information dealing with the ever evolving field of bariatric surgery. Volume II: Integrated Health is divided into 3 sections: bariatric medicine, psychosocial, and nutritional aspects of bariatric surgery. The first section deals with the psychosocial issues associated with severe obesity. The second section deals with the role of obesity medicine physicians in preoperative and postoperative support of the bariatric patients. The nutritional section discusses the preoperative and postoperative nutritional support for the bariatric patient. The ASMBS Textbook of Bariatric Surgery, Volume II: Integrated Health is of great value to surgeons, residents and fellows, obesity medicine physicians, psychologists, psychiatrists, and integrated health members that manage patient affected by the disease of obesity.
  • 1970-
    edited by C. B. Anfinsen, Jr. ; contributors: Vincent G. Allfrey [... et al.].
    Status: Not Checked OutLane Catalog Record
  • 2012
    editor-in-chief, Charles Mueller ; section editors, Stephen A. McClave [and others] ; managing editor, Jennifer M. Kuhn.
  • 2008 CRCnetBASE
    edited by Stephen A. Osmani, Gustavo H. Goldman.
  • 2010 Springer
    Alessandro C. Pasqualotto, editor.
  • 2010
    Natalie Anne Dye.
    This work focuses on the mechanism by which MreB contributes to the maintenance of cell shape in the gram-negative alpha-proteobacterium Caulobacter crescentus. The gene mreB encodes a protein that resembles actin, a eukaryotic cytoskeletal protein. Previously, it was shown that mreB is required to maintain a rod-like shape and localizes to a helical pattern near the cytoplasmic membrane. Here, we show that MreB is associated with regions of active growth in Caulobacter, as mutant strains that mislocalize MreB to the cell poles direct new growth at or near the poles. We present evidence to suggest that MreB contributes to the determination of proper length, width, and curvature through partially distinct mechanisms. The determination of proper width involves the essential proteins MreC and Pbp2, which are encoded in the mreB operon. While MreB and MreC are both required to position the cell wall transpeptidase Pbp2 along the lateral sidewalls and away from midcell, the two do not colocalize and each can maintain its localization in the absence of the other. When MreB is mislocalized to the poles, MreC and Pbp2 do not follow. These data argue against the idea that MreB provides a scaffold-like structure to localize enzymes that directly modify the cell wall. The determination of proper curvature, involves the intermediate filament-like protein, Crescentin. We identify a putative binding site on MreB for Crescentin or other curvature-mediating factors. We also show that the extent to which the subcellular localization of MreB changes over the cell cycle is correlated with cell size, indicating that MreB is involved in the coordination between elongation and division. In addition, we show that in vitro purified MreB spontaneously forms very stable polymers in the presence or absence of nucleotide. These polymers are globular or amorphous and only filamentous when placed on a highly positively charged surface of Poly-L-lysine. These in vitro data suggest that MreB is likely to be regulated at the disassembly step in the cell and that the cellular environment may influence the structure of MreB polymers. Lastly, we present biochemical evidence to support the existence of a disassembly factor in cytoplasmic Caulobacter extract. Together our data suggest that the maintenance of the crescent-rod cell shape in Caulobacter is the result of a complicated balance between MreB's dynamic subcellular localization, polymeric structure, and communication with cellular components.
  • 2011 Springer
    Stefan C. Dombrowski, Karen L. Gischlar, Martin Mrazik.
    "During the past several decades, interest in children's psychological disorders has grown steadily within the research community, resulting in a burgeoning knowledge base. The majority of the attention and funding, not surprisingly, has focused on the more prevalent and well-known conditions. Although this raises the odds that young people with more well-known disorders such as ADHD, autism, and learning disorders will receive much-needed professional assessment and intervention, children with less frequently encountered disorders may experience a higher risk of misdiagnosis and inappropriate treatment"--Back cover.
  • 2005 CRCnetBASE
    Jean-Maurice Vergnaud, Iosif-Daniel Rosca.
  • 2009 Springer
    edited by Johnny L. Matson, Frank Andrasik, Michael L. Matson.
    History, overview, and trends in child and adolescent psychological assessment / Robert W. Heffer, Tammy D. Barry, and Beth H. Garland -- Diagnostic classification systems / Jeremy D. Jewell, Stephen D.A. Hupp, and Andrew M. Pomerantz -- Interview and report writing / Amie E. Grills-Taquechel, Rosanna Polifroni, and Jack M. Fletcher -- Intelligence testing / R.W. Kamphaus, Cecil R. Reynolds, and Katie King Vogel -- Rating scale systems for assessing psychopathology : the Achenbach System of Empirically Based Assessment (ASEBA) and the Behavior Assessment System for Children-2 (BASC-2) / Leslie A. Rescorla -- Neuropsychological disorders of children / WM. Drew Gouvier, Audrey Baumeister, and Kola Ijaola -- Assessment of conduct problems / Nicole R. Powell ... [et al.] -- Evidence-based assessment of attention-deficit hyperactivity disorder (ADHD) / Paula Sowerby and Gail Tripp -- Assessment of mood disorders in children and adolescents / C. Emily Durbin and Sylia Wilson -- Assessment of bipolar disorder in children / Stephanie Danner, Matthew E. Young, and Mary A. Fristad -- Academic assessment / George H. Noell, Scott P. Ardoin, and Kristin A. Gansle -- Behavioral assessment of self-injury / Timothy R. Vollmer, Kimberly N. Sloman, and Carrie S.W. Borrero -- Autism spectrum disorders and comorbid psychopathology / Jessica A. Boisjoli and Johnny L. Matson -- Assessment of eating disorder symptoms in children and adolescents / Nancy Zucker ... [et al.] -- Pain assessment / Frank Andrasik and Carla Rime -- Assessment of pediatric feeding disorders / Cathleen C. Piazza and Henry S. Roane.
  • 2009 Springer
    Con Stough, Donald H. Saklofske, James D.A. Parker, editors.
    Pt. I. Some Theoretical Thoughts on EI -- A Brief Analysis of 20 Years of Emotional Intelligence: An Introduction to Assessing Emotional Intelligence: Theory, Research, and Applications / Con Stough, Donald H. Saklofske and James D. A. Parker -- Psychometrics and the Measurement of Emotional Intelligence / Gilles E. Gignac -- Pt. II. Research on Measures of EI -- An Ability Model of Emotional Intelligence: A Rationale, Description, and Application of the Mayer Salovey Caruso Emotional Intelligence Test (MSCEIT) / Peter K. Papadogiannis, Deena Logan and Gill Sitarenios -- Assessing Emotional Intelligence Using the Emotional Quotient Inventory (EQ-i) and Related Instruments / Laura M. Wood, James D. A. Parker and Kateryna V. Keefer -- Psychometric Properties of the Trait Emotional Intelligence Questionnaire (TEIQue) / K. V. Petrides -- The Genos Emotional Intelligence Inventory: A Measure Designed Specifically for Workplace Applications / Benjamin R. Palmer, Con Stough, Richard Harmer and Gilles Gignac -- The Assessing Emotions Scale / Nicola S. Schutte, John M. Malouff and Navjot Bhullar -- Pt. III. Applying EI Research -- The Importance and Training of Emotional Intelligence at Work / Adrian Furnham -- Performance Based Measures and Practical Validity / John Reid -- The Application of Emotional Intelligence in Industrial and Organizational Psychology / Peter J. Jordan, Jane P. Murray and Sandra A. Lawrence -- Emotional Intelligence and Physical Health / Kateryna V. Keefer, James D. A. Parker and Donald H. Saklofske -- Emotional Intelligence and Clinical Disorders / Karen Hansen, Jenny Lloyd and Con Stough -- The Role of Emotional Intelligence in Education / James D. A. Parker, Donald H. Saklofske, Laura M. Wood and Terri Collin -- Pt. IV. New Directions and Conclusions -- Emotional Intelligence Across Cultures: Theoretical and Methodological Considerations / Gina Ekermans Emotional Intelligence in Sport: Theoretical Linkages and Preliminary Empirical Relationships from Basketball / Con Stough, Mathilde Clements, Lena Wallish and Luke Downey -- Understanding the Neurobiology of Emotional Intelligence: A Review / Joanne C. Tarasuik, Joseph Ciorciari and Con Stough -- New Directions and Alternative Approaches to the Measurement of Emotional Intelligence / Benjamin Orchard, Carolyn MacCann, Ralf Schulze, Gerald Matthews, Moshe Zeidner and Richard D. Roberts.
  • 2007
    Thomas Bossert ... [et al.].
    Status: Not Checked OutLane Catalog Record
    Part 1. Status of human resources for health. Level of human resources for health -- Distribution of human resources of health -- Performance of human resources for health -- Cross-cutting problems concerning human resources for health -- Part 2. Policy levers affecting human resources for health. Financing -- Education -- Management -- Policy-making for human resources for health -- Part 3. Health workforce policy development. Assessing the current status of the health workforce -- Developing criteria for prioritizing problems -- Choosing policies to improve the health workforce -- Sequencing the implementation of policies
  • 2009 Springer
    Sam Goldstein, Jack A. Naglieri, editors.
    Defining the evolving concept of impairment / Sam Goldstein and Jack A. Naglieri -- Measurement of symptom severity and impairment / Lawrence J. Lewandowski, Benjamin J. Lovett, and Michael Gordon -- The role of family and situational problems in understanding and reducing impairment / John W. Eagle -- Relationships between adaptive behavior and impairment / Jeffrey Ditterline and Thomas Oakland -- Psychometric issues in the assessment of impairment / Jack A. Naglieri -- The medical model of impairment / Norma Leclair, Steven Leclair, and Christopher R. Brigham -- The DSM model of impairment / Diana K. Joyce and Allison G. Dempsey -- Measuring impairment in a legal context : practical considerations in the evaluation of psychiatric and learning disabilities / Benjamin J. Lovett, Michael Gordon, and Lawrence J. Lewandowski -- Impairment in children / Gregory A. Fabiano and William E. Pelham Jr. -- Impairment in the geriatric population / Holly Tuokko and Lesley Ritchie -- Assessing occupational disability following trauma and impairment / Jasen M. Walker and Stacey A. Petersen -- Conclusion / Sam Goldstein and Jack A. Naglieri.
  • 2011 ScienceDirect
    Gurumurthy Ramachandran, editor.
    The book represents a systematic look at nanoparticle risks within the paradigm of risk assessment, consider the limitations of this paradigm in dealing with the extreme uncertainties regarding many aspects of nanoparticle exposure and toxicity, and suggest new methods for assessing and managing risks in this context. It considers the occupational environment where the potential for human exposure is the greatest as well as the issues relevant to occupational exposure assessment (e.g., the exposure metric) and the evidence from toxicological and epidemiological studies. A chapter is devoted to how conventional risk assessment can be carried out for a candidate nanoparticle (e.g., carbon nanotubes), and the limitations that arise from this approach. The authors propose several alternate methods in another chapter including screening assessments and adapting the rich methodological literature on the use of experts for risk assessment. Another chapter deals with non-occupational populations, their susceptibilities, and life-cycle risk assessments. There is a chapter on current risk management and regulatory oversight frameworks and their adequacy. This chapter also includes a discussion of US and EU approaches to risk assessment, as well as corporate approaches.
  • 2013 Springer
    Andrea B. Weir, Margaret Collins, editors.
    Ocular toxicity is routinely assessed in toxicology studies conducted for regulatory purposes. Ocular anatomy and physiology and the assessment of ocular toxicity itself can be challenging to scientists involved in the safety assessment of pharmaceuticals, pesticides and other agents. Anatomical and physiological differences between species can impact the nature of ocular effects observed following intended or unintended exposure of ocular tissues to xenobiotics. Ocular Toxicity in Laboratory Animals provides a concise reference addressing ocular anatomy and physiology across species that will enhance the design and interpretation of toxicology studies conducted for regulatory purposes. The book provides an overview of routine and advanced techniques that are used to assess ocular toxicity including slit lamp biomicroscopy, indirect ophthalmoscopy, electrophysiology and imaging methods for the anterior and posterior segments of the eye. Additionally, the book defines the regulatory expectations for pharmaceuticals intended to treat ocular diseases and for other non-pharmaceutical regulated chemicals. With contributions from experts in the field, Ocular Toxicity in Laboratory Animals is an authoritative, accessible guide for toxicologists and other scientists involved in conducting toxicology studies for regulatory purposes and/or reviewing data from such studies.
  • 2006 Springer
    Sana Loue.
    Prologue -- pt. 1. Foundations -- 1. Constructing categories : context and consequences -- 2. Methodological considerations -- pt. 2. Constructs : their definition and use -- 3. Defining race, ethnicity and related constructs -- 4. Defining sex, gender, and sexual orientation constructs -- 5. Race, ethnicity, and sexual orientation in health -- pt. 3. Assessing gender, ethnicity, and related constructs -- 6. Measures of ethnicity, ethnic identification, acculturation, and immigration status -- 7. Measures of sex, gender, gender role, and sexual orientation -- Index.
  • 2014
    Jennifer Kates, Rachel Garfield, Katherine Young, Kelly Quinn, Emma Frazier, Jacek Skarbinsk.
    This issue brief, based on analysis of nationally representative data from the Center s for Disease Control and Prevention's (CDC's ) Medical Monitoring Project (MMP), provides the first such estimates, looking at how many uninsured people with HIV in care could gain new Medicaid coverage, as well as how many could be eligible for subsidized coverage in state Marketplaces. We estimate the impact of state decisions about expanding Medicaid on the reach of the ACA for people with HIV. We also discuss the current and estimated future role of the Ryan White HIV/AIDS Program, which provides care to people with HIV who are uninsured or underinsured. Finally, while our analysis focuses on those who are already in regular care (an estimated 37% of all people living with HIV in the United States, or 45% of those who have been diagnosed with HIV), we also discuss the implications of the ACA for the m ore than 700,000 people with HIV who remain either undiagnosed or not in regular HIV care.
  • 2008 WHO
    Health Metrics Network.
    This assessment tool describes in detail how to undertake a first baseline assessment of a national HIS. The assessment process is intended to be both catalytic and synergistic. It should move stakeholders towards a shared and broader vision of a more coherent, integrated, efficient and useful system. The gap between the existing system and this new vision will be an important stimulus for moving to the next stage of planning national HIS reform. Such an assessment process can also be a mechanism for directly engaging stakeholders and for reinforcing broad-based consensus-building.--Publisher's description.
    Also available: Print – 2008
  • 2005 NAP
    Committee on Assessing Improvements in Cancer Care in Georgia, National Cancer Policy Board ; Jill Eden and Joseph V. Simone, editors ; Institute of Medicine and National Research Council of the National Academies.
  • 2009 Springer
    Ed Diener, editor.
    Introduction--measuring well-being : collected theory and review works / Ed Diener -- Temporal stability and cross-situational consistency of affective, behavioral, and cognitive responses / Ed Diener and Randy J. Larsen -- Assessing subjective well-being: progress and opportunities / Ed Diener -- The evolving concept of subjective well-being: the multifaceted nature of happiness / Ed Diener, Christie Napa Scollon, and Richard E. Lucas -- Review of the satisfactionwith life scale / William Pavot and Ed Diener -- Subjective well-being: the convergence and stability of self-report and non-self-report measures / Ed Sandvik, Ed Diener, and Larry Seidlitz -- Measuring positive emotions / Richard E. Lucas, Ed Diener, and Randy J. Larsen -- Experience sampling: promises and pitfalls, strengths and weaknesses / Christie Napa Scollon, Chu Kim-Prieto, and Ed Diener -- Life-satisfaction is a momentary judgment and a stable personality characteristic: the use of chronically accessible and stable sources / Ulrich Schimmack, Ed Diener, and Shigehiro Oishi -- Happiness is the frequency, not the intensity, of positive versus negative affect / Ed Diener, Ed Sandvik, and William Pavot -- Income's differential influence on judgments of life versus affective well-being / Ed Diener ... [et al.] -- New measures of well-being / Ed Diener ... [et al.] -- Conclusion: future directions in measuring well-being / Ed Diener.
  • 2014 Springer
    Kenneth Shapiro, Mary Lou Randour, Susan Krinsk, Joann L. Wolf.
    Empirical research has clearly demonstrated that animal abuse in childhood is associated with family violence and violent behavior towards humans in general. Such abuse is accordingly of increasing interest within human services and the criminal justice system. This handbook will serve as an ideal resource for therapists in social work, psychology, psychiatry, and allied fields who work with children who have abused animals. It provides step-by-step guidance on how to assess, develop appropriate treatment plans for, and treat children who commit animal abuse, based on the AniCare model developed by the Animals and Society Institute. Exercises cover the identification and expression of feelings, the development of empathy, self-management skills, and working with parents. Careful consideration is also paid to the effects of witnessing animal abuse. The theoretical framework is eclectic, encompassing cognitive behavioral, psychodynamic, and attachment theories. A number of illustrative case studies are included, along with excerpts from treatment sessions. Accompanying electronic supplementary material demonstrates role-played assessment and treatment and includes workshop presentations of pedagogic material.
  • 2009 ebrary, Limited to 3 simultaneous users
    edited by Steven M. Downing, Rachel Yudkowsky.
    Introduction to assessment in the health professions / Steven M. Downing and Rachel Yudkowsky -- Validity and its threats / Steven M. Downing and Thomas M. Haladyna -- Reliability / Rick D. Alexson and Clarence D. Kreiter -- Generalizability theory / Clarence D. Kreiter -- Statistics of testing / Steven M. Downing -- Standard setting / Rachel Yudkowsky, Steven M. Downing, and Ara Tekian -- Written tests : constructed-response and selected-response formats / Steven M. Downing -- Observational assessment / William C. McGahie, John Butter, and Marsha Kaye -- Performance tests / Rachel Yudkowsky -- Simulations in assessment / William C. McGahie and S. Barry Issenberg -- Oral examinations / Ara Tekian and Rachel Yudkowsky -- Assessment portfolios / Ara Tekian and Rachel Yudkowsky.
  • [by Sana Loue].
    Also available: Print – 1999
  • pts. 1-2, 1974.
    Hippius, Hanns.
    Status: Not Checked OutLane Catalog Record
    pt. 1. Psychopharmacological screening tests. pt. 2. Non-invasive methods in cardiovascular human pharmacology.
  • 2014 Springer
    Gabriel Guliš, Odile Mekel, Balázs Ádám, Liliana Cori, editors.
    Public health continues to evolve as professionals work not only to prevent disease and promote well-being but also to reduce health disparities and protect the environment. To a greater extent, policy is intimately linked to this process, a reality that is gaining traction in the public health sector.
  • 2005 NAP
    Committee to Assess Potential Health Effects from Exposures to PAVE PAWS Low-Level Phased-Array Radiofrequency Energy, Board on Radiation Effects Research, Division on Earth and Life Sciences, National Research Council.
  • 2015 Springer
    Enrico Agabiti Rosei, Giuseppe Mancia, editors.
    This book presents up-to-date information on how to assess early preclinical alterations in the heart, the small and large arteries and the kidney in the general and the hypertensive population, using the most sensitive, specific and cost-effective techniques. A wide variety of techniques are discussed, with careful attention to the latest developments. For each organ, evidence is documented regarding the prevalence of organ damage. Information is provided on the potential induction of regression of organ damage by treatment, the criteria for establishing significant changes and the clinical prognostic significance of regression. The manual will be invaluable for all practitioners responsible for the clinical management of hypertensive patients, given that the assessment of early preclinical cardiovascular and renal damage permits more accurate risk stratification at baseline and facilitates evaluation of cardiovascular protection when regression of structural changes is achieved during treatment.
  • 2006
    Yakov Chudnovsky.
    Status: Not Checked OutLane Catalog Record
  • NAP
    Committee on Health Effects Associated with Exposures During the Gulf War, Institute of Medicine.
  • 2012
    Jae Mo Park.
    Unlike normal tissues, solid tumors have a metabolic phenotype that favors energy-inefficient glycolysis rather than more efficient, but oxygen consuming, oxidative phosphorylation, even when oxygen levels are adequate. This metabolic shift towards glycolysis, discovered by Warburg in 1924, has been studied for more than 80 years, but the mechanism of the phenomena is still unclear due to lack of tools for in vivo investigation. Dynamic nuclear polarization in combination with the recent development of a dissolution process that retains the increased polarization into the liquid state opened new possibilities for the real-time investigation of in vivo metabolism using C13 magnetic resonance spectroscopy. In particular, hyperpolarized [1-13C]pyruvate, a substrate occupying a key nodal point in the glucose metabolic pathway, has been successfully demonstrated as a neoplasm biomarker via elevated lactate labeling in tumors. However, additional downstream products of pyruvate metabolism, such as that occur in mitochondria of brain tumor, have been veiled due to low signal-to-noise ratios. The first part of the thesis is on the quantitative assessment of mitochondrial function in normal rat brain and glioma by detecting 13C-bicarbonate following the bolus injection of [1-13C]pyruvate. The feasibility of quantitatively detecting 13C-bicarbonate in tumor-bearing rat brain is demonstrated for the first time. The optimized protocol for chemical shift imaging and high concentration of hyperpolarized [1-13C]pyruvate were used to improve measurements of lactate and bicarbonate in C6 glioma-transplanted rat brains. Moreover, the immediate response to dichloroacetate treatment, which upregulates pyruvate flux to acetyl-CoA, is also presented. It is demonstrated that the simultaneous detection of lactate and bicarbonate provides a tool for a more comprehensive analysis of glioma metabolism and the assessment of metabolic agents as anti-cancer drugs. In the second part of the thesis, further investigation on mitochondrial metabolism, including tricarboxylic acid cycle, is presented by acquiring single-time point chemical shift imaging data from rat brain in vivo after administration of highly concentrated [2-13C]pyruvate. A C13 surface coil optimized for rat brain was built to increase sensitivity of signal detection. [5-13C]glutamate, [1-13C]acetyl carnitine, and [1-13C]citrate were detected besides [2-13C]pyruvate and [2-13C]lactate, for the first time in brain. Change of the tricarboxylic acid cycle activity in brain was also investigated by infusing dichloroacetate. The increase of [5-13C]glutamate was detected primarily from brain, whereas [1-13C]acetyl carnitine was increased in peripheral tissues after the infusion of dichloroacetate. The third part focuses on dynamic measurements of hyperpolarized substrates to obtain exchange rates in addition to concentrations, and proposes the apparent conversion rate as a new metric to detect glioma by comparing the conversion rates in glioma, normal appearing brain, and basilar vasculature in female Sprague-Dawley rats with C6 glioma cells implanted. Whereas single-time point measurements give a snapshot image of tissue metabolism, the estimated apparent rate constant yielded a better differentiation between the tissue types than the lactate-to-pyruvate ratio, which has been the most common metric used to date. This study demonstrates the feasibility of quantitatively detecting C13-labeled bicarbonate and glutamate in vivo, permitting the assessment of dichloroacetate-modulate changes in pyruvate dehydrogenase flux in both normal rat brain and glioma. The simultaneous detection of both lactate dehydrogenase and pyruvate dehydrogenase activities will likely improve our ability to both assess and monitor metabolic therapies of brain and other cancers by providing non-invasive in vivo measures of glycolysis and oxidative phosphorylation.
  • 2007 CRCnetBASE
    John L. Holmes, Christiane Aubry, and Paul M. Mayer.
  • 2005 NCI
  • Guenter Lewy.
    Advances in medical treatment now enable physicians to prolong life to a previously unknown extent, however in many instances these new techniques mean not the saving of life but prolonging the act of dying. In the eyes of many, medical technology has run out of control and contributes to unnecessary suffering. Hence the demand has arisen that patients should be entitled to choose death when pain and physical and mental deterioration have destroyed the possibility of a dignified and meaningful life and that their doctors should help them to realize this endeavor. At the present time there are seven jurisdictions in the world that, with various restrictions, have legalized the practice of assisted death- physician-assisted suicide and/or voluntary euthanasia- to wit, the Netherlands, Belgium, Luxemborg, and Switzerland in Europe and the states of Oregon, Washington and Montana in the United States. Four of these regimes have been functioning for many years, and we have from them a substantial body of data as well as much observational research. This book is based on this material. The literature dealing with the moral, legal and social aspects of assisted death is voluminous, but there is also much writing that provides a detailed accounts of the way that these four regimes are working. Many partisans, on both sides of the issue, cite existing data selectively or, at times, willfully distort the empirical evidence in order to strengthen their case. Based on the documentary record and interviews with officials, this book gives the reader a reliable picture of the way assisted death functions and to draw relevant lessons. While accurate factual information cannot settle a moral debate, it nevertheless is a precondition of any well-founded argument. -- from Book Jacket
  • 2011 ClinicalKey
    [edited by] Jay P. Goldsmith, Edward H. Karotkin ; illustrations by Barbara L. Siede.
    Assisted Ventilation of the Neonate, 5th Edition, by Drs. Jay P. Goldsmith and Edward Karotkin, guides you through the latest innovations in ventilatory assistance, helping you improve outcomes and quality of life in newborns. With a new emphasis on prevention of chronic lung disease and long term neurologic damage, this edition covers basic concepts of pulmonary pathophysiology and offers practical guidance on both basic and advanced ventilation management strategies. Quality improvement strategies such as non-invasive ventilation, early extubation, oxygen targeting and prevention of intraventricular hemorrhage are reviewed. You₂ll also have easy access to the complete contents and illustrations online at expertconsult.com. Access expert coverage of all aspects of neonatal pulmonary care-including complications, nutrition, transport, outcomes, follow-up, and parental education. Sharpen your diagnostic and clinical skills with case studies drawn from actual patients. Find key facts fast with more than 30 quick-reference appendices: normal values, assessment charts, ICU flow charts, procedure steps, and other useful tools. Learn how to best use assisted ventilation equipment and pharmacologic agents to prevent long-term pulmonary and neurologic damage. Benefit from Drs. Goldsmith and Karotkin₂s widely acknowledged expertise in neonatology and pulmonology.
  • 2012
    Audrie Lin.
    Overview: 555 million preschool children live in developing countries where malnutrition (undernutrition) is a significant problem. The factors that contribute to this issue are multiple, with two important factors being gut microbiota and gut function. To begin to understand gut microbiota and gut function in a developing country, we performed two parallel studies: in the first study, we characterized the baseline gut microbiota of healthy Bangladeshi children, and in the second study, we investigated the association between household environmental conditions and gut function in Bangladeshi children. The gut microbiota affect nutrient metabolism, immune function, and pathogen resistance. Loss of gut function as occurs in environmental enteropathy (a multifaceted, subclinical intestinal disorder likely derived from repeated episodes of infectious gastroenteritis and chronic inflammation) contributes to malnutrition and growth faltering. It is possible that these processes are interrelated with the gut microbiota serving a critical role in environmental enteropathy. Gut microbiota: Previous studies have focused on the gut microbiota of infants and adults from developed countries, but few have characterized the gut microbiota of people living in developing countries. Furthermore, little is known about the gut microbiota and its variation over time in primary-school-age children and adolescents in either developed or developing countries. In this study, we compared the monthly variation in fecal microbiota composition of healthy children (ages 8--14 years) living in an urban slum in Bangladesh with that of age-matched children from affluent suburban communities in the United States. We analyzed 8,000 near full-length sequences of the small-subunit ribosomal RNA gene (16S rDNA) and over 845,000 pyrosequencing reads spanning the V1-V3 variable region of the 16S rDNA. The distal gut of Bangladeshi children harbored significantly higher microbial diversity than U.S. children, a result validated by the discovery of several novel lineages from various bacterial phyla in the full-length Bangladeshi dataset. Bangladeshi and U.S. children displayed distinct gut microbiota architectures. Moreover, significantly lower month-to-month temporal stability was observed in Bangladeshi children compared to U.S. children. Together, these results suggest that different environmental or genetic variables may affect the microbiota of healthy children in the two countries. Further studies are necessary to investigate the underlying mechanisms of these differences and to incorporate these insights into prevention or treatment of diseases. Gut function: Although poor water quality, sanitation, and hygiene are putative risk factors for environmental enteropathy, there are no studies investigating the relationship of household environmental conditions to environmental enteropathy. We compared levels of environmental enteropathy markers to growth patterns and measured the prevalence of parasitic infections in children living in different levels of environmental cleanliness based on indictors of water, sanitation, and hygiene in their households. We conducted a follow-up study of 119 children (< 4 years old) from an existing cohort, living in rural Bangladesh and divided into two types of households: a 'mitigated household' had good water quality, improved sanitation, and a handwashing station stocked with water and soap, and a 'contaminated household' had poor water quality, and inadequate sanitation and handwashing facilities. We measured anthropometry, intestinal parasitic infection, and the following markers to assess gut function: Lactulose:Mannitol (L:M) ratio, immunoglobulin G endotoxin core antibody (IgG EndoCAb), and total IgG. After adjustment for potential confounding, children from mitigated households had higher height-for-age Z-scores (HAZ), lower L:M ratios, and lower IgG EndoCAb titers than children from contaminated households. The L:M ratio was also strongly associated with HAZ in the cohort. Children living in environmentally mitigated households had lower levels of parasitic infection, improved measures of gut function, and improved growth compared to children living in contaminated environments. These results support the hypothesis that environmental contamination mediated through environmental enteropathy could be a cause of growth faltering in low-income countries. Interpretation: By characterizing the baseline gut microbiota of healthy children living in a developing country and correlating their gut function with household environmental conditions, our work provides a foundation to address the role of the gut microbiota and environmental enteropathy in child health.
  • by Themistocles L. Assimes ... [et al.].
  • 2007 Springer
    edited by Claudine Elmerich and William E. Newton.
  • 2009 ScienceDirect
    2008 ClinicalKey
    Peter Barnes, Jeffrey Drazen, Stephen Rennard, Neil Thomson.
  • 2010
    edited by Richard J. Martin, E. Rand Sutherland.
    Status: Not Checked OutLane Catalog Record
    Overview of the infection, allergy, and asthma relationship / Dawn C. Newcomb and R. Stokes Peebles Jr. -- Laboratory diagnosis of respiratory infections / Ronald J. Harbeck -- Hygiene hypothesis for allergy and asthma / Andrew H. Liu -- Asthma exacerbation induced by virus and bacteria / Kaharu Samino and Michael J. Walter -- Interaction between allergen and bacteria in chronic asthma / Richard J. Martin -- Viral-allergy interactions / Jonathan D.R. Macintyre, Annemarie Sykes, and Sebastian L. Johnston -- Viral respiratory infections in infancy and chronic asthma / James E. Gern -- Bacterial respiratory infections and asthma / E. Rand Sutherland -- Increased susceptibility to viral infection at the origins of asthma / Fernando D. Martinez -- Pulmonary surfactant, innate immunity, and asthma / Mari Numata and Dennis R. Voelker -- Host defense responses / Hong W. Chu and Favbienne Gally -- Antimicrobial and anti-inflammatory effects of antibiotics : a role in asthma therapy / Druhan Howell and Monica Kraft.
  • 2013 CRCnetBASE
    edited by Jean-Luc Malo, Moira Chan-Yeung, and David I. Bernstein.
  • 2012 Springer Protocols
    edited by Richard Milner.
    Astrocytes : multitalented stars of the central nervous system / Bruce R. Ransom and Christoher B. Ransom -- Neurogenic astrocytes and their glycoconjugates : not just "glue" anymore / Dennis A. Steindler -- Heterogeneity of astrocytic form and function / Nancy Ann Oberheim, Steven A. Goldman, and Maiken Nedergaard -- Preparation of mixed glial cultures from postnatal rat brain / Jean de Vellis and Ruth Cole -- Generation of primary astrocyte cultures devoid of contaminating microglia / Tracy F. Uliasz [and others] -- Derivation of microglia-free astrocyte cultures from neural stem cells / Jennifer V. Welser and Richard Milner -- Isolation and culture of spinal cord astrocytes / Amber E. Kerstetter and Robert H. Miller -- Isolation and culture of astrocytes from the retina and optic nerve / Thomas J. Lukas and Ai Ling Wang -- Primary cultures of astrocytes from fetal bovine brain / Cristina Ballarin and Antonella Peruffo -- Isolation and cultivation of porcine astrocytes / Dennis J. Bobilya -- Isolation and culture of human astrocytes / Ariane Sharif and Vincent Prevot -- Cell culturing of Caenorhabditis elegans glial cells for the assessment of cytosolic Ca² dynamics / Randy F. Stout Jr. and Vladimir Parpura -- Astrocyte polarization and wound healing in culture : studying cell adhesion molecules / H. Peng and S. Caronetto -- An in vitro trauma model to study rodent and human astrocyte reactivity / Ina-Beate Wanner -- Use of gel zymography to examine matrix metalloproteinase (gelatinase) expression in brain tissue or in primary glial cultures / Harald Frankowski [and others] -- ELISA methodology to quantify astrocyte production of cytokines/chemokines in vitro / Hongwei Qin and Etty N. Benveniste -- Induction of nitric oxide synthase-2 expression and measurement of nitric oxide production in enriched primary cortical astrocyte cultures / James A. Hewett and Sandra J. Hewett -- Examining potassium channel function in astrocytes / Michelle Olsen -- Connexin-based channels in astrocytes : how to study their properties / Christian Giaume [and others] -- Isotope-based quantitation of uptake, release, and metabolism of glutamate and glucose in cultured astrocytes / Leif Hertz -- An in vitro model of reactive astrogliosis and its effect on neuronal growth / Panpan Yu [and others] -- A neuron-astrocyte co-culture system to investigate astrocyte-secreted factors in mouse neuronal development / Emma V. Jones, Denise Cook, and Keith K. Murai -- Cocultures of neurons and astrocytes as a model for examining hypoxia-induced neuronal death / Giuliano Rita, Terho Emily, and David A. Rempe -- Use of astrocyte-microglial cocultures to examine the regulatory influence of astrocytes on microglial activation / Jennifer V. Welser and Richard Milner -- Astrocyte-Schwann-cell coculture systems / Fardad T. Afshari and James W. Fawcett -- An in vitro assay to examine oligodendrocyte precursor cell migration on astrocytes / Fardad T. Afshari and James W. Fawcett -- Investigation of astrocyte-oligodendrocyte interactions in human cultures / Gareth R. John -- An improved in vitro blood-brain barrier model : rat brain endothelial cells co-cultured with astrocytes / N. Joan Abbott [and others] -- In vitro models of the blood-brain barrier / Kaushik K. Shah, Li Yang, and Thomas J. Abbruscato -- An in vitro model of ischemic stroke / Li Yang, Kaushik K. Shah, and Thomas J. Abbruscato -- Pericyte coculture models to study astrocyte, pericyte, and endothelial cell interactions / Vladimir Katyshev and Paula Dore-Duffy -- Reprogramming of postnatal astroglia of the mouse neocortex into functional, synapse-forming neurons / Christophe Heinrich, Magdalena Götz, and Benedikt Berninger -- Assessment of glial function in the in vivo retina / Anja I. Srienc [and others] -- Imaging in vivo astrocyte/endothelial cell interactions at the blood-brain barrier / Colin L. Willis -- Transgenic techniques for cell ablation or molecular deletion to investigate functions of astrocytes and other GFAP-expressing cell types / Michael V. Sofroniew -- In vivo imaging of Ca²⁺ signaling in astrocytes using two-photon laser scanning fluorescent microscopy / Shinghua Ding -- Use of Cre-lox technology to analyze integrin functions in astrocytes / Aaron K. Mobley and Joseph H. McCarty.
  • 2009 Springer
    Vladimir Parpura, Philip G. Haydon, editors.
  • 2013 Springer
    Stacey Schultz-Cherry, editor.
    Since their initial discovery in the 1970's, astroviruses have been recognized as a leading cause of enteritis in infants, the elderly, and immunocompromised people, and were known to be widespread in animals and birds. In recent years, and with the advent of pyrosequencing, there has been a virtual explosion in the number of newly identified astrovirus genotypes. With this has come an increased understanding in astrovirus biology, structure, epidemiology, immunology, and disease pathogenesis including the likelihood of extraintestinal and systemic infections. The advent of new diagnostic tests that detect all of the currently identify human astrovirus strains may prove that these viruses are more prevalent in populations than currently realized.This book will provide state-of-the-art information on our current understanding of astroviruses for researchers, medical and veterinary providers, and diagnosticians as prepared by the leaders in the respective fields. The goal is to bring the reader up to date on the state of knowledge on this constantly evolving and exciting field of virology.
  • 2007
    Enoch Callaway.
    Status: Not Checked OutLane Catalog Record
    "In his witty and warm history of Worcester State Hospital, founded in 1833 as the first state insane asylum in this nation, Dr. Enoch Callaway reflects not just on the events in this fortress-like place, but also on how those events parallel advances and failures in the field of psychiatry itself. He includes patient/psychiatrist vignettes showing treatment techniques of the period - from farm work to early electric shock therapy and insulin treatments that put schizophrenics in a 90-minute coma. In addition, he offers sharp insight into 'natural' treatments that showed remarkable results, as well as into unexpected recoveries stimulated by tools as simple as a hand mirror. At times, Worcester may seem brutal, at other times its simplicity seems pure and caring. There are marvelous successes, and times when the facility seems no more than a warehouse for the mentally ill. Callaway argues that this history offers lessons about the treatment - and options for better treatment - of the mentally ill in society today."--Book jacket.
  • 2014 ebrary
    Charles S. Bryan.
    Dr. James Woods Babcock, superintendent of the South Carolina State Hospital for the Insane from 1891 to 1914, led the American response to pellagra, producing the first English-language treatise on the disease and organizing the meetings of the National Association for the Study of Pellagra.
  • 2007 Springer
    Alvaro Macieira-Coelho (ed.).
  • 2007
    Wei-Shen Chen.
    Status: Not Checked OutLane Catalog Record
  • 2010 Springer
    edited by Morteza Naghavi.
  • 2010
    Kathy Barker.
    Status: Not Checked OutLane Catalog Record
  • 2006/2007
    Joe Dan Dunn.
    Status: Not Checked OutLane Catalog Record
  • 2012 ScienceDirect
    volume editors, Sankara H. Subramony and Alexandra Dürr.
  • 2010 Springer
    Francesco Broccolo ; presentazione a cura di Gianfranco Parati , Giancarlo Cesana.
  • 2013 Springer
    edited by Allen J. Taylor, Todd C. Villines.
    Atherosclerosis: Clinical Perspectives Through Imaging is aimed at practicing clinicians and relies on didactic tabular and bullet points and a host of fine imagery describing the common features of the imaging of atherosclerosis, enabling the reader to understand more about the advantages and limitations of each modality in investigating athersclosis. Edited by and contributed to by a host of international experts in cardiac imaging, this book is a must read by all who image the heart.
  • 2005 Springer
    editor, Arnold von Eckardstein ; contributors, J. Ahrens ... [et al.].
  • 2008 Springer
    Jordan L. Holtzman.
  • 2011 Springer
    Jasjit S. Suri, Chirinjeev Kathuria, Filippo Molinart, editors.
    Atherosclerosis is a degenerative process affecting blood vessels, which determines narrowing of the lumen, plaque growth, and hardening of the walls. It is a risk factor for cardiovascular diseases. The focus of this book is on the management of the atherosclerotic disease. The coverage of this book spans from histological presentation of the various stages of atherosclerotic lesions to the earliest studies in atherosclerosis therapy, from advanced clinical diagnosis to monitoring, follow-up, and home-care of the atherosclerotic patient. The book shows well-established diagnostic techniques covering several medical imaging modalities such as Ultrasounds, IVUS, MRI, Computer Tomography, along with new trends in early and advanced atherosclerosis diagnosis (innovative drugs and tissue characterization procedures). Surgical standards will be presented along with innovative experimental trials for the treatment of the atherosclerotic patient. The book will also cover emerging techniques based on molecular imaging and vibro-acoustics.
  • 1964.
    Giertsen, J. C.
  • 2007 Karger
    volume editors, Michel E. Safar, Edward D. Frohlich.
  • 2015 Wiley
    edited by Hong Wang and Cam Patterson.
  • 2009 ClinicalKey
    [edited by] Kevin E. Wilk, Michael M. Reinold, James R. Andrews.
    The latest edition of this in-depth look at athletic injuries of the shoulder has been updated to feature 16 new chapters, additional illustrations and algorithms, an added focus on arthroscopic treatments, and pearls that highlight key information. Additional contributing authors give you a fresh spin on new and old topics from rehabilitation exercises to special coverage of female athletes, pediatrics, and golfers. This book offers coverage of arthroscopy, total joint replacement, instability, football, tennis, swimming, and gymnastic injuries, rotator cuff injuries, and much, much more! The large range of topics covered in this text ensures that it's a great resource for orthopaedists, physical therapists, athletic trainers, and primary care physicians. Presents a multidisciplinary approach to the care of the shoulder, combining contributions from the leaders in the field of orthopedic surgery, physical therapy, and athletic training. Demonstrates which exercises your patients should perform in order to decrease their chance of injury or increase strength following an injury through illustrated exercises for rehabilitation and injury prevention. Illustrates how the shoulder is affected during activity of certain sports with a variety of tables and graphs. Covers a large range of topics including all shoulder injuries to be sufficiently comprehensive for both orthopaedists and physical therapists/athletic trainers.
  • 2013 Springer
    Jan Tolleneer, Sigrid Sterckx, Pieter Bonte, editors.
    The book provides an in-depth discussion on the human nature concept from different perspectives and from different disciplines, analyzing its use in the doping debate and researching its normative overtones. The relation between natural talent and enhanced abilities is scrutinized within a proper conceptual and theoretical framework: is doping to be seen as a factor of the athlete's dehumanization or is it a tool to fulfill his/her aspirations to go faster, higher and stronger? Which characteristics make sports such a peculiar subject of ethical discussion and what are the, both intrinsic and extrinsic, moral dangers and opportunities involved in athletic enhancement? This volume combines fundamental philosophical anthropological reflection with applied ethics and socio-cultural and empirical approaches. Furthermore it presents guidelines to decision- and policy-makers on local, national and international levels.
  • 2007
    Status: Not Checked OutLane Catalog Record
  • 2008
    Dua, Tarun; Rompani, Paul.
    Status: Not Checked OutLane Catalog Record
  • 2007
    Status: Not Checked OutLane Catalog Record
  • 2007 Ovid
    David E. Elder, Rosalie Elenitsas, Bernett L. Johnson, Jr., Michael D. Ioffreda, Jeffrey Miller, O. Fred Miller.
  • 2008 Springer
    Jacques Derhy.
  • Google Books
    Salamon, Henrik.
    Bd. 1. Brückenarbeiten.
    Also available: Print – v. 1, 1909.

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