• 2014From: Springer
    Vincenzo Zappia, Salvatore Panico, Gian Luigi Russo, Alfredo Budillon, Fulvio Della Ragione, editors.
    This book comprises proceedings from the Third International Conference on Advances in Nutrition and Cancer, held in Naples in May 2012. This highly multidisciplinary meeting analyzed nutrition and cancer from different perspectives and on the basis of distinct and up-to-date experimental approaches. Knowledge on the relation between lifestyle, diet, and cancer is explored in a number of contributions, and the role of dietary intervention in cancer patients is discussed. Issues of vital interest to the research community, such as epidemiological and experimental oncology (genetics, epigenetics, and the mechanisms of action of natural compounds in the diet), receive detailed consideration. A further key topic is the emerging molecular technologies (the -omics) that can cast light on the interplay between nutrition and human malignancies. Chapters take the form of reviews that include sections presenting expert opinions. Advances in Nutrition and Cancer will be an invaluable source of topical information for all researchers and clinicians with an interest in this field.
    Also available: Print – 2014
  • 2012From: Future Med
    editor, Peter E. Schwartz.
    Advances in ovarian cancer management / Peter E. Schwartz -- Etiology and overview / Gang Ye, Stefanie Bernaudo & Chun Peng -- Diagnostic imaging in the management of ovarian masses / Amit Mahajan, Indukala Doddamane & Shirley McCarthy -- Initial surgical management of ovarian cancer / Jason Knight & Peter G. Rose -- Initial chemotherapy for the treatment of ovarian cancer / Katherine M. Moxley & Robert S. Mannel -- Neoadjuvant chemotherapy in the management of advanced ovarian cancer / Peter E. Schwartz -- Intraperitoneal chemotherapy : its use in epithelial ovarian cancer / Neesha Dhani & Helen Mackay -- Chemotherapeutic management of recurrent ovarian cancer / Marcia Hall -- Emerging chemotherapy agents in ovarian cancer / Daliah Tsoref & Amit M. Oza -- Surgical management of recurrent ovarian cancer / Eelco de Bree -- Angiogenesis in ovarian cancer / Vincent Castonguay & Amit M. Oza -- Antigen-specific immunotherapy for ovarian cancer / Dana M. Roque & Alessandro D. Santin -- Poly(ADP-ribose) polymerase inhibitors and epithelial ovarian cancer -- Thomas P. McNally, Gillianne G.Y. Lai & Richard T. Penson -- Emerging targeted therapies / Mirko Marabese & Massimo Broggini -- Palliative care in ovarian cancer / Cynthia O'Sullivan, Elizabeth Ercolano & Ruth McCorkle -- Guidelines in ovarian cancer / Domenica Lorusso, Antonella Pietragalla & Giovanni Scambia -- Index.
  • 2011From: Future Med
    editors, Helmut Friess, Norbert Hüser.
    Advances in pancreatic cancer treatment / Helmut Friess & Norbert Hüser -- Pathophysiology of pancreatic cancer / J. Matthias Löhr, Stephan L. Haas & Rainer Heuchel -- Molecular diagnostics in pancreatic cancer / David K. Chang, Sean M. Grimmond & Andrew V. Biankin -- Surgical therapy for pancreatic cancer / Norbert Hüser, Volker Assfalg & Helmut Friess -- Multimodal treatment concepts in pancreatic cancer / Daniel Reim, Alexander Novotny & Helmut Friess -- Consensus guidelines in pancreatic cancer treatment / Wasif Saif -- Drugs in clinical trials & future directions / Zhiqiang Huang & Donald J. Buchsbaum.
  • 2011From: Future Med
    editor, Joseph H. Friedman.
    Advances in Parkinson's disease management / Joseph H. Friedman -- Etiology and overview / Witold Polanski -- Biomarkers of Parkinson's disease / Mauro Fasano & Tiziana Alberio -- Imaging Parkinson's disease / David J. Brooks -- Dopaminergic agents / Lawrence W. Elmer & Robert A. Hauser -- Combined dopaminergic and nondopaminergic therapies / Mary Ann Thenganatt & Cheryl H. Waters -- Future drug therapy / Makoto Naoi & Wakako Maruyama -- Drug therapies for neuropsychiatric and autonomic disturbances in patients with PD / Thomas Müller -- Surgical treatment for Parkinson's disease / Sumito Sato & Hideki Mochizuki -- Cell and gene transplantation for Parkinson's disease : from the clinic / Paul E. Greene -- Current evidence-based guidelines for the management of Parkinson's disease / Nicolas Phielipp & Janis Miyasaki -- Index.
  • edited by Rowena Korobkin, Christian Guilleminault.
    PrintStatus: Not Checked OutLane Catalog Record
  • 2007From: Springer
    Santiago González-Moreno, editor.
    Management of Peritoneal Surface Malignancy: A Short History / Paul H. Sugarbaker -- The Natural History of Free Cancer Cells in the Peritoneal Cavity / Yutaka Yonemura, Taiichi Kawamura, Etsurou Bandou, Gorou Tsukiyama and Yoshio Endou, et al. -- Pathological Evaluation and Implications of Serosal Involvement in Gastrointestinal Cancer / Linmarie Ludeman and Neil A. Shepherd -- Principles of Perioperative Intraperitoneal Chemotherapy for Peritoneal Carcinomatosis / Eelco de Bree and Dimitris D. Tsiftsis -- Experimental and Pharmacokinetic Studies in Intraperitoneal Chemotherapy: From Laboratory Bench to Bedside / Eelco de Bree and Dimitris D. Tsiftsis -- Technology for the Delivery of Hyperthermic Intraoperative Intraperitoneal Chemotherapy: A Survey of Techniques / Amod A. Sarnaik, Jeffrey J. Sussman, Syed A. Ahmad, Benjamin C. McIntyre and Andrew M. Lowy -- Adjuvant Intraperitoneal Chemotherapy: A Review / Paul H. Sugarbaker -- Clinical Research Methodology in Peritoneal Surface Oncology: A Difficult Challenge / François-Noël Gilly, Olivier Glehen, Annie C. Beaujard and Eddy Cotte -- Lessons Learnt from Clinical Trials in Peritoneal Surface Oncology: Colorectal Carcinomatosis / Frans A. N. Zoetmulder and Vic J. Verwaa -- Experimental Models and Questions in Basic Science Research for Pseudomyxoma Peritonei / Laura A. Lambert, Donald H. Lambert and Paul Mansfield -- Peritoneal Carcinomatosis of Colorectal Origin: Recent Advances and Future Evolution Toward a Curative Treatment / Dominique Elias and Diane Goere -- Pathologic Characterization and Differential Diagnosis of Malignant Peritoneal Mesothelioma / Nelson G. Ordóñez -- Advances in Clinical Research and Management of Diffuse Peritoneal Mesothelioma / Marcello Deraco, Dario Baratti, Nadia Zaffaroni, Antonello Domenico Cabras and Shigeki Kusamura -- Advances in the Management of Gastric Cancer with Peritoneal Dissemination / Yutaka Yonemura, Taiichi Kawamura, Etsurou Bandou, Gorou Tsukiyama and Masayuki Nemoto, et al. -- Intraperitoneal Chemotherapy in the Management of Ovarian Cancer / Maurie Markman.
    Also available: Print – 2007
  • 2011From: Future Med
    editor, Dimitrios H. Roukos.
    Personalized genomic medicine: is a cancer care revolution achievable? / Dimitrios H. Roukos -- Targeting the individual cancer patient / Georgios Baltogiannis, Christos S. Katsios & Dimitrios H. Roukos -- Biomarkers-guided targeted drugs: new clinical trials design and practice necessity / Ming-Wen An, Sumithra J. Mandrekar & Daniel J. Sargent -- Personalized management for breast cancer / George C. Zografos, Dimosthenis T. Chrysikos, Paraskevi Liakou & Flora Zagouri -- Personalized management for non-small-cell lung cancer / Martin Früh, Florent Baty, Lukas Kern, Martin P. Putora & Martin Brutsche -- Personalized management for colorectal cancer / Ana Custodio & Jaime Feliu -- Successes, challenges and future directions / Stephen J. Clarke.
  • 2011From: Future Med
    editor, Nagahiro Saijo.
    Advances in personalized therapy for lung cancer / Nagahiro Saijo -- Biomarkers in lung cancer / Tobenna Nwizu & Ravi Salgia -- EGF receptor-targeted drugs / Tetsuya Mitsudomi -- Antiangiogenic therapies for non-small-cell lung cancer / Suresh S. Ramalingam & Chandra P. Belani -- DNA-targeted drugs / Judith Meza-Junco & Michael B. Sawyer.
  • 2007From: Springer
    edited by Fangsen Xu, Heiner E. Goldbach, Patrick H. Brown, Richard W. Bell, Toru Fujiwara, Curtiss D. Hunt, Sabine Goldberg, and Lei Shi.
  • v. 1-9, 2012-15.From: Springer
    Golubnitschaja, Olga.
  • 2007From: Springer
    Peter Lucas, José A. Gámez, Antonio Salmerón, eds.
  • 2014From: Springer
    edited by Jeffrey M. Weinberg, Mark Lebwohl.
    The understanding and management of psoriasis have evolved dramatically over the last decades and, as a result, guidelines and treatment options have changed dramatically. To meet the need for a up-to-date practical resource in this area, the Editors have brought together a team of experts in the field to produce a highly informative and illustrated guide to the decision-making process for psoriasis. Advances in Psoriasis: A Multisystemic Guide provides physicians with a reference on the disease and its comorbidities and therapeutic options. It will help physicians further their knowledge of the science and therapy of psoriasis. As well as practicing dermatologists, fellows in dermatology will find this book to be an essential training resource to learn about the treatment and management of psoriasis.
  • v. 5-, 1967-From: Karger
    Wise, Thomas N.
  • 2013From: Future Med
    editor, Kjell Öberg.
    Advances in pulmonary neuroendocrine tumor management / Kjell Öberg -- Classification / Mauro Papotti -- Molecular imaging & peptide receptor radionuclide therapy / Richard P. Baum, Harshad R. Kulkarni & Dieter Hörsch -- Biotherapy : somatostatin analogs and IFN-[alpha] / Dan Granberg -- Typical and atypical bronchial carcinoid tumors / Michael Beckles, Dalvinder Mandair, Christos Toumpanakis & Martyn Caplin -- Small-cell lung cancer and large-cell neuroendocrine tumors of the lung / David Planchard & Eric Baudin -- Thymic neuroendocrine tumors / Piero Ferolla -- Algorithm for management of bronchopulmonary neuroendocrine tumors / Kjell Öberg -- Index.
  • Jeffrey Y.C. Wong, Timothy E. Schultheiss, Eric H. Radany, editors.
    Combining radiotherapy and immunotherapy -- SBRT and the treatment of oligometastatic disease -- MRI guided radiotherapy -- Oncologic applications of magnetic resonance guided focused ultrasound -- Intensity-modulated proton beam therapy of prostate cancer- history, results, and future directions -- IGRT and hypofractionation for primary tumors -- The impact of IGRT on normal tissue toxicity -- Biologic and image guided systemic radiotherapy -- Cancer stem cells and tumor microenvironment in radiotherapy -- Biomarkers and radiotherapy -- The mammalian DNA damage response as a target for therapeutic gain in radiation oncology -- Mathematical modeling in radiation oncology.
  • 2011From: Springer
    Branislav Jeremić (editor) ; foreword by Luther W. Brady ... [et al.].
  • 2012From: Springer
    Gabriella Castoria, Antimo Migliaccio, editors.
    [1.] Non-genomic Action of Steroid Hormones: More Questions than Answers / Antimo Migliaccio, Gabriella Castoria, Antonio Bilancio, Pia Giovannelli, Marzia Di Donato and Ferdinando Auricchio -- Part I. Breast Cancer -- [2.] Progesterone Signaling to Chromatin in Breast Cancer Cells. Two Initial Cycles of Remodeling / Guillermo P. Vicent, Roser Zaurin, Cecilia Ballaré, A. Silvina Nacht, Roni H. G. Wright, Francois Le Dily, Giancarlo Castellano, Jofre Font-Mateu and Miguel Beato -- [3.] Cooperative Interactions Between c-Src, Estrogen Receptors and Receptor Tyrosine Kinases in Breast Cancer / Sarah J. Parsons, Jessica E. Pritchard, Emily M. Fox and Margaret A. Shupnik -- [4.] Cross Talk Between ER[alpha] and Src Signaling and Its Relevance to ER Status and Hormone Responsiveness / Jun Sun, Wen Zhou, Zafar Nawaz and Joyce M. Slingerland -- [5.] Post-translational Modifications of ER Alpha in Rapid Estrogen's Action / Muriel Le Romancer, Coralie Poulard, Stéphanie Sentis, and Laura Corbo -- [6.] Sex-Steroid Rapid Action and Its Role in Invasiveness and Metastasis of Breast Cancer / Marina Ines Flamini, Angel Matias Sanchez, Xiao-Dong Fu and Tommaso Simoncini -- [7.] Unraveling the Role of GPER in Breast Cancer / Rosamaria Lappano and Marcello Maggiolini -- [8.] Nongenomic Actions of Estrogens and Xenoestrogens Affecting Endocrine Cancer Cells / Cheryl S. Watson, Dragoslava Zivadinovic, Yow-Jiun Jeng, Rebecca A. Alyea, Terumi Midoro-Horiuti, Randall Goldblum and Anannya Banga -- Part II. Prostate Cancer -- [9.] Differential Functions of Stromal and Epithelial Androgen Receptor in Prostate Cancer Before and After Castration Resistant Stage / S. Lee, K.-P. Lai, S. Yeh and C. Chang -- [10.] Role of Androgens and Androgen Receptor in Prostate Cancer: Genomic and Non-Genomic Actions / Sara Marchiani, Lara Tamburrino, Monica Muratori, Lorella Bonaccorsi, Gianni Forti and Elisabetta Baldi -- [11.] Mechanisms of Signal Transduction in Prostate Cancer: The Role of PI3-Kinase Pathway in Androgen Action / Laurent Morel and Silvère Baron -- [12.] The IGF-I Axis in Prostate Cancer: The Role of Rapid Steroid Actions / Antonino Belfiore -- Androgen Receptor Pathway in Prostate Cancer: Old Target and New Drugs / Christophe Massard and Karim Fizazi -- Part III. New Tools for Steroid Receptor Analysis and Regulatory Networks -- [13.] Quantitative Visualization of Sex Steroid Receptor Functions: AR and ER[alpha] / Michael J. Bolt, Sean M. Hartig, Adam T. Szafran, Sanjay N. Mediwala, Marco Marcelli and Michael A. Mancini -- [14.] Micropatterned Surfaces as Tools for the Study of the Rapid Non-genomic Actions of Steroid Receptors / Andrew C. B. Cato, Emmanuel Oppong and Sylwia Sekula-Neuner.
  • 2007From: Ovid
    editors, S. Robert Kovac, Carl W. Zimmerman.
  • 2010From: Springer
    edited by Venkatram Prasad Shastri, George Altankov, Andreas Lendlein.
    Cell Adhesions and Signaling: A Tool for Biocompatibility Assessment / Roumen Pankov and Albena Momchilova -- Development of Provisional Extracellular Matrix on Biomaterials Interface: Lessons from In Vitro Cell Culture / George Altankov, Thomas Groth, Elisabeth Engel, Jonas Gustavsson and Marta Pegueroles, et al. -- Endothelial Progenitor Cells for Tissue Engineering and Tissue Regeneration Endothelial Progenitor Cells / Joyce Bischoff -- Dermal Precursors and the Origins of the Wound Fibroblast / Jeffrey M. Davidson -- Cell Based Therapies: What Do We Learn from Periosteal Osteochondrogenesis? / Peter J. Emans, Tim J. M. Welting and Venkatram Prasad Shastri -- Bioreactor Systems in Regenerative Medicine / Ivan Martin, Stefania A. Riboldi and David Wendt -- Biomimetic Approaches to Design of Tissue Engineering Bioreactors / Bojana Obradovic, Milica Radisic and Gordana Vunjak-Novakovic -- The Nature of the Thermal Transition Influences the Shape-Memory Behavior of Polymer Networks / Andreas Lendlein, Marc Behl and Stefan Kamlage -- Nanoengineered Systems for Regenerative Medicine Surface Engineered Polymeric Biomaterials with Improved Bio-Contact Properties / Todorka Vladkova and Natalia Krasteva -- Nanocomposites for Regenerative Medicine / Ryan Hoshi, Antonio R. Webb, Hongjin Qiu and Guillermo A. Ameer -- Role of Spatial Distribution of Matricellular Cues in Controlling Cell Functions / Daniela Guarnieri and Paolo A. Netti -- Materials Surface Effects on Biological Interactions / Josep A. Planell, Melba Navarro, George Altankov, Conrado Aparicio and Elisabeth Engel, et al. -- Chemical and Physical Modifications of Biomaterial Surfaces to Control Adhesion of Cells / Thomas Groth, Zhen-Mei Liu, Marcus Niepel, Dieter Peschel and Kristin Kirchhof, et al. -- Results of Biocompatibility Testing of Novel, Multifunctional Polymeric Implant Materials In-Vitro and In-Vivo / Dorothee Rickert, Rosemarie Fuhrmann, Bernhard Hiebl, Andreas Lendlein and Ralf-Peter Franke -- UFOs, Worms, and Surfboards: What Shapes Teach Us About Cell-Material Interactions / Julie A. Champion and Samir Mitragotri -- Nano-engineered Thin Films for Cell and Tissue-Contacting Applications / Richard F. Haglund -- Injectable Hydrogels: From Basics to Nanotechnological Features and Potential Advances / Biancamaria Baroli -- Polyelectrolyte Complexes as Smart Nanoengineered Systems for Biotechnology and Gene Delivery / Vladimir A. Izumrudov.
  • 2016From: Springer
    Mieczyslaw Pokorski, editor.
    The role of dysregulated microRNA expression in lung cancer / M. Krutakova [and seven others] -- Laryngeal cancer: 12-year experience of a single center / V. Calkovsky, P. Wallenfels, A. Calkovska, A. Hajtman -- Polymorphisms of selected DNA repair genes and lung cancer in chromium exposure / E. Halasova, [and nine others] -- Associations of CYP1A2 polymorphisms with the risk haplotypes in lung cancer in the Slovak population -- T. Matakova, E. Halasova, A. Dzian, R. Hruby, M. Halasa, K. Javorka, M. Skerenova -- Impact of endobronchial ultrasound guided transbronchial needle aspiration on diagnostic yield of bronchoscopy in patients with mediastinal lymph node enlargement -- K. Osinka, M. Zielińska-Krawczyk, P. Korczyński, B. Górnicka, R. Krenke -- The effect on cognition of mitochondrial respiratory system proteins in peripheral blood mononuclear cells in the course of lung cancer -- S. Michalak, J. Rybacka-Mossakowska, J. Gazdulska, I. Gołda-Gocka, R. Ramlau -- Lung cancer and multiple neoplasms: a retrospective analysis -- A. Romaszko, E. Świetlik, A. Doboszyńska, P. Szpruch, J. Luks -- Humoral immune response against neural antigens and its effects on cognition in lung cancer patients -- J. Rybacka-Mossakowska, R. Ramlau, J. Gazdulska, I. Gołda-Gocka, W. Kozubski and S. Michalak. -- Active case finding among homeless people as a means of reducing the incidence of pulmonary tuberculosis in general population -- J. Romaszko, A. Siemaszko, M. Bodzioch, A. Buciński, A. Doboszyńska -- Cryptogenic organizing pneumonia: IL-1[beta], IL-6, IL-8, and TGF- [beta]1 serum concentrations and response to clarithromycin treatment -- E. Radzikowska and [six others].
    Also available: Print – 2016
  • 2015From: Springer
    Charles F. Streckfus.
    This book reviews the progress made in salivary diagnostics and identifies the likely direction of future endeavors. After an introductory section describing the histological and anatomical features of the salivary glands and salivary function, salivary collection devices and diagnostic platforms are reviewed. The field of ĺlsalivaomicsĺl is then considered in detail, covering, for example, proteomics, the peptidome, DNA and RNA analysis, biomarkers, and methods for biomarker discovery. Salivary diagnostics for oral and systemic diseases are thoroughly discussed, and the role of salivary gland tissue engineering for future diagnostics is explored. The book closes by considering legal issues and barriers to salivary diagnostic development. Advances in Salivary Diagnostics will be an informative and stimulating reference for both practitioners and students.
  • 2010From: Springer
    Wagner F. Gattaz, Geraldo Busatto, editors.
  • 2016From: Springer
    Kazuya Tamai, Eiji Itoi, Kenji Takagishi, editors.
    Chapter 1. Anatomy -- Chapter 2. Biomechanics -- Chapter 3. Kinematics and Motion Analysis -- Chapter 4. Advanced MR Imaging of the Shoulder -- Chapter 5. Transosseous-Equivalent Arthroscopic Bankart Repair by Twin Anchor Footprint Fixation (TAFF) Technique using JuggerKnot Soft Anchor -- Chapter 6. Complications of Arthroscopic Surgery -- Chapter 7 Instability -- Chapter 8. Arthroscopic Rotator Cuff Repair -- Chapter 9. Mini-Open Rotator Cuff Repair -- Chapter 10. Massive and Irreparable Rotator Cuff Tears -- Chapter 11. Superior Capsule Reconstruction for Massive Rotator Cuff Tears -- Chapter 12. Tendon Transfer for Massive Rotator Cuff Tear -- Chapter 13. Frozen Shoulder -- Chapter 14. Nerve Lesions Around the Shoulder -- Chapter 15. Proximal Humeral Fractures - Classification and Treatment -- Chapter 16. Reverse Shoulder Arthroplasty -- Chapter 17. Physical Therapy- Tips and Pitfalls.
  • 2012From: Karger
    volume editor, Karl Lenhard Rudolph.
    Speakers at the symposium / Morita, M. -- Aging of the niche and the microenvironment and its role in stem cell aging / Geiger, H. -- Hematopoietic stem cell aging and cancer / Chen, Y., Ju, Z. -- DNA damage, checkpoint responses, and cell cycle control in aging stem cells / Kleinhans, K.N., Burkhalter, M.D. -- Hematopoietic stem cell aging and fate decision / Illing, A., Morita, Y. -- Stem cell therapy and stress response in pancreas and intestine -- Sperka, T., Omrani, O. -- Niche-stem cell interations and environmental influences / Tang, D. -- Stem cells and metabolism / Missios, P., Guachalla, L. -- Molecular mechanisms of muscle stem cell aging / Baig, A.H., Tümpel, S. -- Neural stem cells in development and aging / Schmidt-Strassburger, U.
  • 2012From: Springer
    Hossein Baharvand, Nasser Aghdami, editors.
    Advances in stem cell research discusses recent advances in stem cell science, including therapeutic applications. This volume covers such topics as biomanufacturing iPS cells for therapeutic applications, techniques for controlling stem cell fate decisions, as well as current basic research in such areas as germ line stem cells, genomics and proteomics in stem cell research. It is a useful book for biology and clinical scientists, especially young investigators and stem cell biology students who are newly entering the world of stem cells research. The editors hope that the new knowledge and research outlined in this book will help contribute to new therapies for a wide variety of diseases that presently afflict humanity.
  • 2012From: Springer
    Igor I. Goryanin, Andrew B. Goryachev, editors.
    Part 1. Multiscale biological networks: identification, modeling and analysis -- Modular Analysis of Biological Networks / Hans-Michael Kaltenbach and Jörg Stelling -- Modeling Signaling Networks Using High-throughput Phospho-proteomics / Camille Terfve and Julio Saez-Rodriguez -- An Integrated Bayesian Framework for Identifying Phosphorylation Networks in Stimulated Cells / Tapesh Santra, Boris Kholodenko and Walter Kolch -- Signaling Cascades: Consequences of Varying Substrate and Phosphatase Levels / Elisenda Feliu, Michael Knudsen and Carsten Wiuf -- Heterogeneous Biological Network Visualization System: Case Study in Context of Medical Image Data / Erno Lindfors, Jussi Mattila, Peddinti V. Gopalacharyulu, Antti Pesonen and Jyrki Lötjönen, et al. -- Evolution of the Cognitive Proteome: From Static to Dynamic Network Models / J. Douglas Armstrong and Oksana Sorokina -- Molecular Systems Biology of Sic1 in Yeast Cell Cycle Regulation Through Multiscale Modeling / Matteo Barberis -- Proteome-Wide Screens in Saccharomyces cerevisiae Using the Yeast GFP Collection / Yolanda T. Chong, Michael J. Cox and Brenda Andrews -- Unraveling the Complex Regulatory Relationships Between Metabolism and Signal Transduction in Cancer / Michelle L. Wynn, Sofia D. Merajver and Santiago Schnell -- Part 2. Cellular decision making: adaptation, differentiation and death -- The Cell as a Thermostat: How Much does it Know? / Dennis Bray -- Stem Cell Differentiation as a Renewal-Reward Process: Predictions and Validation in the Colonic Crypt / Kiran Gireesan Vanaja, Andrew P. Feinberg and Andre Levchenko -- A Dynamic Physical Model of Cell Migration, Differentiation and Apoptosis in Caenorhabditis elegans / Antje Beyer, Ralf Eberhard, Nir Piterman, Michael O. Hengartner and Alex Hajnal, et al. -- A Modular Model of the Apoptosis Machinery / E. O. Kutumova, I. N. Kiselev, R. N. Sharipov, I. N. Lavrik and Fedor A. Kolpakov -- An Ensemble Approach for Inferring Semi-quantitative Regulatory Dynamics for the Differentiation of Mouse Embryonic Stem Cells Using Prior Knowledge / Dominik Lutter, Philipp Bruns and Fabian J. Theis -- Cell Death and Life in Cancer: Mathematical Modeling of Cell Fate Decisions / Andrei Zinovyev, Simon Fourquet, Laurent Tournier, Laurence Calzone and Emmanuel Barillot -- Theoretical Aspects of Cellular Decision-Making and Information-Processing / Tetsuya J. Kobayashi and Atsushi Kamimura -- Zooming in on Yeast Osmoadaptation / Clemens Kühn and Edda Klipp -- Part 3. Spatial and temporal dymensions of intracellular dynamics -- Receptor Dynamics in Signaling / Verena Becker, Jens Timmer and Ursula Klingmüller -- A Systems-Biology Approach to Yeast Actin Cables / Tyler Drake, Eddy Yusuf and Dimitrios Vavylonis -- Modeling Morphodynamic Phenotypes and Dynamic Regimes of Cell Motion / Mihaela Enculescu and Martin Falcke -- Time-Structure of the Yeast Metabolism In vivo / Kalesh Sasidharan, Masaru Tomita, Miguel Aon, David Lloyd and Douglas B. Murray -- Coarse Graining Escherichia coli Chemotaxis: From Multi-flagella Propulsion to Logarithmic Sensing / Tine Curk, Franziska Matthäus, Yifat Brill-Karniely and Jure Dobnikar -- Self-Feedback in Actin Polymerization / Anders E. Carlsson -- Part 4. Computational tools, algorithms and theoretical methods for systems biology -- Global Optimization in Systems Biology: Stochastic Methods and Their Applications / Eva Balsa-Canto, J. R. Banga, J. A. Egea, A. Fernandez-Villaverde and G. M. de Hijas-Liste -- Mathematical Modeling of the Human Energy Metabolism Based on the Selfish Brain Theory / Matthias Chung and Britta Göbel -- Identification of Sensitive Enzymes in the Photosynthetic Carbon Metabolism / Renato Umeton, Giovanni Stracquadanio, Alessio Papini, Jole Costanza and Pietro Liò, et al. -- Formal Methods for Checking the Consistency of Biological Models / Allan Clark, Vashti Galpin, Stephen Gilmore, Maria Luisa Guerriero and Jane Hillston -- Global Parameter Identification of Stochastic Reaction Networks from Single Trajectories / Christian L. Müller, Rajesh Ramaswamy and Ivo F. Sbalzarini -- A Systems Biology View of Adaptation in Sensory Mechanisms / Pablo A. Iglesias -- Leveraging Modeling Approaches: Reaction Networks and Rules / Michael L. Blinov and Ion I. Moraru -- Part 5. Applications of systems biology in medicine, biotechnology and pharmaceutical industry -- Why and How to Expand the Role of Systems Biology in Pharmaceutical Research and Development / Robert D. Phair -- Multiscale Mechanistic Modeling in Pharmaceutical Research and Development / Lars Kuepfer, Jörg Lippert and Thomas Eissing -- Re-analysis of Bipolar Disorder and Schizophrenia Gene Expression Complements the Kraepelinian Dichotomy / Kui Qian, Antonio Di Lieto, Jukka Corander, Petri Auvinen and Dario Greco -- Bringing Together Models from Bottom-Up and Top-Down Approaches: An Application for Growth of Escherichia coli on Different Carbohydrates / Andeas Kremling -- A Differential Equation Model to Investigate the Dynamics of the Bovine Estrous Cycle / H. M. T. Boer, C. Stötzel, S. Röblitz and H. Woelders -- Reducing Systems Biology to Practice in Pharmaceutical Company Research; Selected Case Studies / N. Benson, L. Cucurull-Sanchez, O. Demin, S. Smirnov and P. van der Graaf -- System-Scale Network Modeling of Cancer Using EPoC / Tobias Abenius, Rebecka Jörnsten, Teresia Kling, Linnéa Schmidt and José Sánchez, et al. -- Early Patient Stratification and Predictive Biomarkers in Drug Discovery and Development / Daphna Laifenfeld, David A. Drubin, Natalie L. Catlett, Jennifer S. Park and Aaron A. Van Hooser, et al. -- Biomedical Atlases: Systematics, Informatics and Analysis / Richard A. Baldock and Albert Burger.
    Also available: Print – 2012
  • 2013From: Future Med
    editors, Kimberly A. Smith, Dustin R. Fraidenburg, Jason X.-J. Yuan
    Current therapies for the treatment of pulmonary arterial hypertension / Kimberly A. Smith, Dustin R. Fraidenburg & Jason X.-J. Yuan -- Etiology and prevalence of pulmonary arterial hypertension / Catharina Belge & Marion Delcroix -- Pathology and diagnosis of pulmonary arterial hypertension / Carlyne D. Cool -- Conventional therapy / Stefania Cicalini & Nicola Petrosillo -- Targeted therapies : prostaglandins / Benton Ashlock & David Poch -- Targeted therapies : endothelin receptor antagonists / Kimberly A. Smith, Dustin R. Fraidenburg & Jason X.-J. Yuan -- Stimulators and activators of soluble guanylate cyclase : potential therapeutic indications / Bobby D. Nossaman, George F. Lasker, Edward A. Pankey, Raj D. Parikh & Philip J. Kadowitz -- Surgical approaches in pulmonary arterial hypertension / Vaidehi Kaza, Jodie Moore, Srinivas Bollineni & Fernando Torres -- Monitoring and prognosis of pulmonary arterial hypertension / Melanie J. Brewis & Andrew J. Peacock -- Right ventricular failure / Raj Parikh & Philip J. Kadowitz -- Index.
  • 2009.From: Karger
    volume editor, T. Hugh Jones.
    Current guidelines for the diagnosis of testosterone deficiency / S. Arver, M. Lehtihet -- Laboratory measurement of testosterone / M.J. Diver -- Advances in testosterone replacement therapy / L.J.G. Gooren -- The role of the CAG repeat androgen receptor polymorphism in andrology / M. Zitzmann -- Late-onset hypogonadism / L.J.G Gooren -- Testosterone in obesity, metabolic syndrome, and type 2 diabetes / R.D. Stanworth, T.H. Jones -- Testosterone and coronary artery disease / J.E. Nettleship ... [et al.] -- Erectile dysfunction and testosterone deficiency / M. Blute ... [et al.] -- Testosterone, bone, and osteoporosis / S.P. Tuck, R.M. Francis -- Frailty and muscle function : role for testosterone? / U. Srinivas-Shankar, F.C.W. Wu -- Testosterone effects on cognition in health and disease / M.M. Cherrier -- Anabolic applications of androgens for functional limitations associated with aging and chronic illness / S. Bhasin, T.W. Storer -- Testosterone in chronic heart failure / C.J. Malkin, T.H. Jones, K.S. Channer -- Testosterone and prostate safety / A. Morgentaler, C. Schulman.
  • 2011From: Future Med
    editors, Clifford A. Hudis, Tiffany A. Traina.
    Advances in the management of triple-negative breast cancer / Tiffany A. Traina & Clifford A. Hudis -- Etiology and risk factors / Laura Fejerman & Elad Ziv -- Diagnosis and pathology / Govardhanan Nagaiah & Jame Abraham -- Molecular subtypes and emerging therapeutic opportunities / Anastasia Constantinidou, Robin L. Jones & Jorge S. Reis-Filho -- Molecular profile of triple-negative breast cancer / Leonel F. Hernandez-Aya & Ana Maria Gonzalez-Angulo -- Role of metabolic rehabilitation-based approach in TNBC : biguanide metformin and more / Lev M. Berstein, Garik A. Dashyan & Vladimir F. Semiglazov -- Poly(ADP-ribose) polymerase inhibitors in triple-negative breast cancer / Mark Robson -- Targeted therapies: EGFR inhibitors / Farrah M. Datko & Maura N. Dickler -- Targeted therapies : other agents in clinical trials / Brian R. Haney, Nathan M. Shumway & George E. Peoples -- Combined therapies and future directions / Anastasia Pazaiti & Ian S. Fentiman.
  • 2010From: CRCnetBASE
    edited by Cynthia M. Kuhn, George F. Koob.
    Advances in animal models of relapse for addiction research / Friedbert Weiss -- Application of chronic extracellular recording method to studies of cocaine self-administration : method and progress / Laura L. Peoples, Alexai V. Kravitz, and Karine Guillem -- Neurochemistry of addiction : monitoring essential neurotransmitters of addiction / Stefan G. Sandberg and Paul A. Garris -- Alcohol craving and relapse prediction : imaging studies / Andreas Heinz ... [et al.] -- Integrating behavioral and molecular approaches in mouse : self-administration studies / Danielle L. Graham and David W. Self -- Neuroeconomics : implications for understanding the neurobiology of addiction / Michael L. Platt ... [et al.].
  • 2012From: Future Med
    editor, Michael D. Prados.
    Advances in the pathogenesis and treatment of glioblastoma multiforme / Michael Prados -- Pathogenesis, molecular characteristics and prognostic factors for survival / Keith L. Ligon -- Standard treatment approaches for newly diagnosed glioblastoma / Soon-Tae Lee & Patrick Y. Wen -- Targeted therapeutic strategies for relapsed disease / John F. de Groot & Howard Colman -- Genes, viruses, toxins and vaccines as therapeutic modalities / Tal Shahar, Manish K. Aghi & Zvi Ram -- Drug delivery strategies for glioblastoma / Pin-Yuan Chen, Dali Yin, John Forsayeth & Krystof S. Bankiewicz -- Index.
  • 2012From: Future Med
    editors, Michael J. Keating, Constantine Tam.
    Advances in the treatment of B-cell chronic lymphocytic leukemia / Michael J. Keating & Constantine Tam -- Chronic lymphocytic leukemia : diagnosis and clinical staging / Stephen P. Mulligan & Constantine S. Tam -- Genetics in chronic lymphocytic leukemia / Stephan Stilgenbauer & Thorsten Zenz -- To treat or not to treat / Marco Montillo, Alessandra Tedeschi & Enrica Morra -- Chronic lymphocytic leukemia chemotherapy : two decades of progress / Carol Moreno & Emili Montserrat -- Stem cell transplantation / David G. Maloney -- Treatment options for refractory chronic lymphocytic leukemia / Marina Motta & Alessandra Ferrajoli -- Prognostic markers in chronic lymphocytic leukemia / Renata Walewska & David Oscier -- Therapeutic agents in development and future direction / Sarah Mougalian & Susan O'Brien -- Index.
  • 2013From: Future Med
    editors, Giuseppe Saglio, Carmen Fava.
    Advances in the treatment of chronic myeloid leukemia / Giuseppe Saglio & Carmen Fava -- Diagnosis and classification of the risk / Gabriele Gugliotta, Fausto Castagnetti, Francesca Palandri, Michele Baccarani & Gianantonio Rosti -- Genetics of chronic myeloid leukemia / Giovanna Rege-Cambrin, Emilia Giugliano & Patrizia Scaravaglio -- Molecular monitoring / Martin C. Müller, Christian Dietz & Benjamin Hanfstein -- Current targeted therapy with tyrosine kinase inhibitors / Massimo Breccia & Giuliana Alimena -- Stem cell transplantation and high-dose chemotherapy / Deena Iskander, Jane F. Apperley & Jirí Pavlu -- Treatment options for tyrosine kinase inhibitor-resistant chronic myeloid leukemia / Stephan Joseph Dorkhom, Hady Ghanem & Elias Jabbour -- Prognostic factors and future direction for chronic myeloid leukemia / David Marin & Antonia Rotolo -- Chronic myeloid leukemia : the possibility of a cure / Manuel Sobrinho-Simões, David M. Ross & Junia V. Melo -- Index.
  • 2011From: Springer
    David Wallach, Andrew Kovalenko, Marc Feldmann, editors.
    Roles of the TNF family in tissue homeostasis and normal development -- Novel aspects of signaling activation by the TNF family: novel aspects of the functions of the TRAFs and cIAPs -- Novel aspects of signaling activation by the TNF: ubiquitin modification of signaling proteins -- Novel aspects of signaling activation by the TNF family: TNF signaling and gene regulatory networks -- Roles of the TNF family in infectious diseases and interrelationship of the TNF family and pattern recognition receptor signaling: roles of the TNF family in infectious diseases -- Roles of the TNF family in infectious diseases and interrelationship of the TNF family and pattern recognition receptor signaling: interrelationship of the TNF family and pattern recognition receptor signaling -- Novel aspects of immune regulation by the TNF family -- Control of lymphocyte function and repertoire by the TNF family -- Advances in applying our knowledge to therapy: mechanisms of pathological and therapeutic effects of the TNF family -- Advances in applying our knowledge to therapy: rational design of new means for therapeutic modulation of function of the TNF family -- Roles of the TNF family in neuronal development, function, and pathology -- Cell death mechanisms controlled by the TNF family -- Contributors to abstracts of talks and posters at the 12th TNF Conference -- Abstracts of talks and posters presented at the 12th TNF Conference.
    Also available: Print – 2011
  • volume editors, Elizabeth M. Dax, Albert Farrugia, Girish N. Vyas.
  • 2015From: Springer
    Fiona Zwald, Marc D. Brown, editors.
    This book provides an informative update on scientific advances relating to transplant dermatology that may be applicable to clinical practice. Commentary is provided on the emerging role of viruses in transplant dermatology, the management of skin disease secondary to transplant medication, sunscreen use in transplant recipients, the role of revision of immunosuppression, and advances in photodynamic therapy. The latest staging and management criteria for high-risk squamous cell carcinoma and the implications for clinical practice are then analyzed. Finally, the management of other cutaneous malignancies is discussed, covering malignant melanoma, Merkel cell carcinoma, and rarer tumors that also behave aggressively and require special consideration in solid organ transplant patients. Each particular advance is addressed in an individual chapter by leaders in the field. The book both expands current knowledge and complements previous textbooks on the subject.
  • 2014From: Springer
    Joseph D. Rosenblatt, Eckhard R. Podack, Glen N. Barber, Augusto Ochoa, editors
    Recent advances in understanding of fundamental immunology have created new insights into the dynamic interactions between tumors and the immune system. This includes new understanding of T- and B-cell interaction, immune inhibitory mechanisms including the biology of T regulatory cells, myeloid suppressor cells, and dendritic cell subsets. Enhanced understanding of mechanisms underlying T-cell anergy such as arginine deprivation, immunosuppressive cytokines, defective innate and interferon response pathways, and NKG2D downregulation have all provided new insight into suppression of anti-tumors.
  • 2009From: Springer
    Teruhisa Kazui, Shinichi Takamoto, editors.
  • 2011From: CRCnetBASE
    edited by Tadeusz Marek, Waldemar Karwowski, Valerie Rice.
  • 2012From: Springer
    Russell H. Vreeland, editor.
    Approaches toward the study of halophilic microorganisms in their natural environments : who are they and what are they doing? / Aharon Oren -- Media and conditions for the growth of halophilic and halolerant bacteria and ardchaea / Mark A. Schneegurt -- Taxonomy of halophilic archaea and bacteria / Antonio Ventosa ... [et al.] -- Halophilic viruses / Shereen Sabet -- Microorganisms in evaporites : review of modern geomicrobiology / Tim K. Lowenstein -- Searching for microbes and DNA in ancient halite / Russell H. Vreeland -- DNA replication and repair in halophiles / Adrienne Kish and Jocelyne DiRuggiero -- Gene transfer mechanisms, population genetics/genimics and the evolution of haloarchaea / R. Thane Papke and Scott Chimileski -- Worth your salt : halophiles in education / Bonnie K. Baxter, Jaimi K. Butler and Betsy Kleba -- Halophiles in the public media / Russell H. Vreeland.
  • 2010From: Springer
    David Abraham ... [et al.], (eds.).
  • 2008From: ScienceDirect
    edited by Inga D. Neumann, Rainer Landgraf.
    Nonapeptides and the evolutionary patterning of sociality / J.L. Goodson -- Sex differences in vasopressin and oxytocin innervation of the brain / G.J. de Vries -- The parvocellular vasopressinergic system and responsiveness of the hypothalamic pituitary adrenal axis during chronic stress / G. Auilera ... [et al.] -- Experimental approaches for the study of oxytocin and vasopressin gene expression in the central nervous system / E.M. Scordalakes, C. Yue and H. Gainer -- Oxytocin knockout mice: a model for studying stress-related and ingestive behaviours / J.A. Amico ... [et al.] -- The role of the vasopressin 1b receptor in aggression and other social behaviours / H.K. Caldwell, S.R. Wersinger and W.S. Young III -- Behavioural studies using temporal and spatial inactivation of the oxytocin receptor / H.-J. Lee ... [et al.] -- New aspects of oxytocin receptor function revealed by knockout mice: sociosexual behavior and control of energy balance / K. Nishimori ... [et al.] -- Regulation of vasopressin release by co-released neurotransmitters: mechanisms of purinergic and adrenergic synergism / C.D. Sladek and Z. Song -- Neuron-glia interactions in the rat supraoptic nucleus / S.H.R. Oliet ... [et al.] -- Dynamic synapses in the hypothalamic-neurohypophyseal system / K.J. Iremonger and J.S. Bains -- Endogenous modulators of synaptic transmission: cannabinoid regulation in the supraoptic nucleus / N.A. McDonald ... [et al.] -- Oxytocin and appetite / G. Leng ... [et al.] -- Neural mechanisms underlying the milk ejection burst and reflex / G.I. Hatton and Y.-F. Wang -- Oxytocin receptor signaling / D. Devost, P. Wrzal and H.H. Zingg -- Neurosteroids are excitatory in supraoptic neurons but inhibitory in the peripheral nervous system: it is all about oxytocin and progesterone receptors / C. Viero and G. Dayanithi -- Oxytocin receptors: ligand binding, signaling and cholesterol dependence / G. Gimpl ... [et al.] -- Opposite effects of oxytocin and vasopressin on the emotional expression of the fear response / D. Viviani and R. Stoop -- Multi-factorial somato-dendritic regulation of phasic spike discharge in vasopressin neurons / C.H. Brown ... [et al.] -- Neurophysiology of supraoptic neurons in C57/BL mice studied in three acute in vitro preparations / R. Sharif-Naeini ... [et al.] -- Effects of oxytocin on GABA signalling in the foetal brain during delivery / R. Khazipov, R. Tyzio and Y. Ben-Ari -- Central vasopressin and oxytocin release: regulation of complex social behaviours / A.H. Veenema and I.D. Neumann -- Interactions between dopamine and oxytocin in the control of sexual behavior / T.A. Baskerville and A.J. Douglas -- Steroidal/neuropeptide interactions in hypothalamus and amygdale related to social anxiety / E. Choleris ... [et al.] -- Functional magnetic resonance imaging and the neurobiology of vasopressin and oxytocin / C.F. Ferris -- Evolution of the arginine vasopressin 1a receptor and implications for mammalian social behaviour / G. Heckel and S. Fink -- Oxytocin, vasopressin and sociality / C.S. Carter ... [et al.] -- Neuropeptides and social behaviour: effects of oxytocin and vasopressin in humans / M. Heinrichs and G. Domes -- Chronic stress plasticity in the hypothalamic paraventricular nucleus / J.P. Herman, J. Flak and R. Jankord -- Keeping oxytocin neurons under control during stress in pregnancy / P.J. Brunton and J.A. Russell -- Rapid synapse-specific regulation of hypothalamic magnocellular neurons by glucocorticoids / S. Di and J.G. Tasker -- Vasopressin in the septum: not important versus casually involved in learning and memory - two faces of the same coin? / M. Engelmann -- Role of the endocannabinoid system in regulation of the hypothalamic-pituitary-adrenocortical axis / M.A. Steiner and C.T. Wotjak -- Molecular genetic studies of the arginine vasopressin 1a receptor (AVPR1a) and the oxytocin receptor (OXTR) in human behaviour: from autism to altruism with some notes in between / S. Israel ... [et al.] -- Oxytocin and experimental therapeutics in autism spectrum disorders / J.A. Bartz and E. Hollander -- Impact of prosocial neuropeptides on human brain function / A. Meyer-Lindenberg -- Peptide and non-peptide agonists and antagonists for the vasopressin and oxytocin V1[a], V1[b], V2 and OT receptors: research tools and potential therapeutic agents / M. Manning ... [et al.] -- Affinity and efficacy of selective agonists and antagonists for vasopressin and oxytocin receptors: an "easy guide" to receptor pharmacology / B. Chini, M. Manning and G. Guillon -- Prevention of hypoxic brain oedema by the administration of vasopressin receptor antagonist OPC-31260 / A.H. Molnár ... [et al.] -- Characterization of a novel and selective V1[B] receptor antagonist / M. Craighead ... [et al.] -- Molecular mechanisms of clinical concentrating and diluting disorders / R.W. Schrier -- Action-binding channels / Y. Noda and S. Sasaki -- Opposite potentiality of hypothalamic coexpressed neuropeptides, apelin and vasopressin in maintaining body-fluid homeostasis / C. Llorens-Cortes and F. Moos -- Recent discoveries in vasopressin-regulated aquaporin-2 trafficking / R.A. Fenton and H.B. Moeller -- Pathophysiological role of aquaporin-2 in impaired water excretion / S.-e. Ishikawa ... [et al.] -- Potential utility of aquaporin modulators for therapy of brain disorders / M.C. Papadopoulos and A.S. Verkman.
  • 2012From: Springer
    Alzira Maria Paiva de Almeida, Nilma Cintra Leal, editors.
    Also available: Print – 2012
  • Fang-Chieh Chou.
    RNA plays critical roles in fundamental biological processes, including transcription, translation, post-transcriptional regulation of genetic expression, and catalysis as enzymes. These critical RNA functions are determined by the structures and dynamics of the RNA molecules. Computational methods might be used to predict the structures and dynamics of RNA. Unfortunately, the prediction accuracies of current computational methods are still inferior compared to experiments. In this dissertation, I discuss recent advances I made in improving and developing computational methods to make accurate predictions on the RNA structures and dynamics. The dissertation contains three individual research projects. In the first part, I present a protocol for Enumerative Real-space Refinement ASsisted by Electron density under Rosetta (ERRASER). ERRASER combined RNA structure prediction algorithm with experimental constraints from crystallography, to correct the pervasive ambiguities in RNA crystal structures. On 24 RNA crystallographic datasets, ERRASER corrects the majority of steric clashes and anomalous backbone geometries, improves the average Rfree by 0.014, resolves functionally important structural discrepancies, and refines low-resolution structures to better match higher resolution structures. In the second part, I present HelixMC, a package for simulating kilobase-length double-stranded DNA and RNA (dsDNA and dsRNA) under external forces and torques, which is typical in single-molecule tweezers experiments. It recovered the experimental bending persistence length of dsRNA within the error of the simulations and accurately predicted that dsRNA's "spring-like" conformation would give a two-fold decrease of stretch modulus relative to dsDNA. In the third part, I developed a framework of Reweighting of Energy-function Collection with Conformational Ensemble Sampling (RECCES), to predict the folding free energies of RNA duplexes. With efficient sampling and reweighting, RECCES allows comprehensive exploration of the prediction power of Rosetta energy function, and provides a powerful platform for testing future improvement of the energy function. In all the projects above, I leveraged rich datasets from previous experiments to develop novel algorithms that gave predictions with unprecedented accuracies, which were validated by independent blind tests. These computational methods I developed could also serve as a solid foundation for future efforts of improving prediction accuracies of RNA computational algorithms.
  • 2012From: CRCnetBASE
    edited by Ingrid Kohlstadt.
    "This book features chapters leading physicians in disease management applying the latest scientific advances linking nutrition to the clinical practice of medicine. Each chapter offers adjuncts to standard care, fewer side-effects, improved risk-reduction or added quality of life"--Provided by publisher.
  • 2013Limited to 1 simultaneous usersFrom: ProQuest Ebook Central
    Tracy Davis, Laura M. Harrison ; foreword by Larry D. Roper.
  • 2013From: Springer
    Omer Mei-Dan, Michael R. Carmont, editors.
    1. The Management of the Extreme Sports Athlete / Omer Mei-Dan and Michael R. Carmont -- 2. Rock and Ice Climbing / Volker Schöffl -- 3. Alpine Skiing and Snowboarding Injuries / Mike Langran -- 4. Skydiving / Anton Westman -- 5. BASE Jumping / Omer Mei-Dan -- 6. Whitewater Canoeing and Rafting / Jonathan P. Folland and Kate Strachan -- 7. Surfing Injuries / Andrew T. Nathanson -- 8. Kite Surfing and Snow Kiting / Mark Tauber and Philipp Moroder -- 9. Windsurfing / Daryl A. Rosenbaum and Bree Simmons -- 10. Sailing and Yachting / Michael R. Carmont -- 11. Mountain Biking Injuries / Michael R. Carmont -- 12. Paragliding / Lior Laver and Omer Mei-Dan -- 13. Mountain, Sky, and Endurance Running / Denise Park and Michael R. Carmont -- 14. Personality Characteristics in Extreme Sports Athletes: Morbidity and Mortality in Mountaineering and BASE Jumping / Erik Monasterio -- 15. Endocrine Aspects and Responses to Extreme Sports / Karen Tordjman, Naama Constantini, and Anthony C. Hackney -- 16. Preventing Injuries in Extreme Sports Athletes / John Nyland and Yee Han Dave Lee -- 17. Rehabilitation of Extreme Sports Injuries / Peter Malliaras, Dylan Morrissey, and Nick Antoniou.
  • 2007From: CRCnetBASE
    edited by Alexander W. Kott, William M. McEneaney.
    Featuring approaches that draw from disciplines such as artificial intelligence and cognitive modeling, this book describes technologies and applications that address a broad range of practical problems, including military planning and command, military and foreign intelligence, antiterrorism and domestic security, as well as simulation and training systems. The authors present an overview of each problem and then discuss approaches and applications, combining theoretical rigor with accessibility. This comprehensive volume covers intent and plan recognition, deception discovery, and strategy formulation.
  • 2012From: Karger
    volume editor, Lars E. French.
    "The skin is one of the most frequently involved organs in adverse drug reactions. Occurring with an incidence of 1 to 5 percent for certain types of drugs, cutaneous drug eruptions are mostly benign in nature, and comprise the maculopapular type of eruption and urticaria. However, about one third of them require hospital treatment, leading to a considerable burden for the health care system. In this book, a selected group of experts provide an up-to-date, condensed and clinically relevant overview of the field of cutaneous drug eruptions, ranging from epidemiology and genetic predisposition to available therapeutic measures, including rapid drug desensitization. Reflecting the great progress made in recent years in this field, this publication will be a useful tool for a better understanding, diagnosis and management of cutaneous drug eruptions, not only for general physicians, dermatologists and clinical allergologists, but also for nurses and scientists." -- publisher's site.
  • 2014From: Springer
    Esen Özkaya, Kurtuluş Didem Yazganoğlu.
    This book describes adverse cutaneous drug reactions as among the most frequent events in patients receiving drug therapy. Cardiovascular drugs are an important group as there are a greater number of indications for the use of new drugs and their prescription continues to increase. The exact incidence of cutaneous side effects from cardiovascular drugs is difficult to estimate due to sporadic reporting. Moreover, a reliable connection between a certain drug and a certain type of reaction can only rarely be made, aside from the well-known angioedema/urticaria from angiotensin-converting enzyme inhibitors, lichen planus/lichenoid reaction from beta adrenergic blockers, and photosensitivity from thiazid diuretics. These reactions can extend to rare but life-threatening conditions such as erythroderma, Stevens-Johnson syndrome, toxic epidermal necrolysis and drug hypersensitivity syndrome. Adverse Cutaneous Drug Reactions To Cardiovascular Drugs reviews the reported types of reactions to cardiovascular drugs. Each is discussed according to drug class and the type of dermatologic reaction with special emphasize on cross-reactions and the role of patch testing in diagnosis. A total of 116 images are included featuring clinical appearance of common adverse cutaneous drug reactions and diagnostic procedures such as patch and photopatch testing with the suspected drugs. Complementary tables may allow to scan the most common cutaneous reactions and the related cardiovascular drugs along with the possible cross reactions at first glance. It will thus be of considerable importance to all dermatologists and medical professionals who manage the skin, while being an important reference resource for cardiologists in terms of identifying potential adverse reactions to the drugs they prescribe.
  • 2010From: Springer
    Jack Uetrecht, editor.
    Pt. 1. Target organ toxicity. -- Drug-induced liver injury / Michael Holt, Cynthia Ju.-- Drug herpersensitivity reactions involving skin / Oliver Hausmann, Benno Schnyder, Werner J. Pichler.-- Adverse drug reactions affecting blood cells / Richard H. Aster.-- Molecular mechanisms of adverse drug reactions in cardiac tissue / Reza Tabrizchi.-- Mechanisms of drug-induced nephrotoxicity / Thomas D. Nolin, Jonathan Himmelfarb.-- Receptor- and reactive intermediate-mediated mechanisms of teratogenesis / Peter G. Wells, Crystal J.J. Lee, Gordon P. McCallum, Julia Perstin, Patricia A. Harper.-- Pt. II. Mediators/Biochemical pathways.-- Role of reactive metabolites in drug-induced hepatotoxicity / A.M. Srivastava, J. L. Maggs, D. J. Antoine, D. P. Williams, D. A. Smith, B. K. Park.-- Role of cytokines in the mechanism of adverse drug reactions / Mary Jane Masson, Lindsay A. Collins, Lance R. Poh.-- Keap1-Nrf2 cellular defense pathway: mechanisms of regulation and role in protection against drug-induced toxicity / Ian M. Copple, Christopher E. Goldring, Neil R. Kitteringham, B. Kevin Park.-- Signal transduction pathways involved in drug-induced liver injury / Derick Han, Mie Shinohara, Maria D. Ybanez, Behnam Saberi, Neil Kaplowitz.-- Mictrochondrial involvement in drug-induced liver injury / Dominique Pessayre, Abdellah Mansouri, Alain Berson, Bernard Fromenty.-- Pt. III. Examples/Models.-- Mechanisms of acetaminophen-induced liver necrosis / Jack A. Hinson, Dean W. Roberts, Laura P. James.-- Drug-induced liver injury in humans: the case of Ximelagtran / M. Keisu, T.B. Andersson.-- Troglitazone / Tsuyoshi Yokoi.-- Neviropine hypersensitivity / M. Popovic, J.M. Shenton, J. Chen, A. Baban, T. Tharmanathan, B. Mannargudi, D. Abdulla, J.P. Uetrecht.-- Mechanisms of adverse drug reactions to biologics / Janet B. Clarke.-- Pt. IV. Risk factors/Screening drug candidates.-- Pharmacogenetics of idiosyncratic adverse drug reactions / Munir Pirmohamed.-- Danger hypothesis applied to idiosyncratic drug reactions / Jinze Li, Jack P. Uetrecht.-- Approaches for minimizing metabolic activation of new drug candidates in drug discovery / Sanjeev Kumar, Kaushik Mitra, Kelem Kassahun, Thomas A. Baillie.
  • 2012From: ScienceDirect
    edited by Bengt Fadeel, Antonio Pietroiusti, Anna A. Shvedova.
    A. Engineered nanomaterials: hazard, exposure and safety assessment. Interactions with the human body / Renato Colognato ... [et al.] -- Exposure assessment / Antonio Bergamaschi, Ivo Iavicoli and Kai Savolainen -- Biomonitoring / Enrico bergamaschi and Andrea Magrini -- Critical evaluation of toxicity tests / Maria Dusinska ... [et al.] -- Computational approaches / Vidana Epa, Dave Winkler and Lang Tran -- Regulation and legislation / Maureen R. Gwinn and Birgit Sokull-Klüttgen -- B. Engineered nanomaterials: impact on human health. Respiratory system / Ken Donaldson and Craig Poland -- Cardiovascular system / Jennifer B. Raftis, Nicholas L. Mills and Rodger Duffin -- Neurological system / Sandra Ceccatelli and Giuseppe Bardi -- Immune system / Diana Boraschi and Albert Duschl -- Skin / Nancy A. Monteiro-Riviere and Francesca Larese Filon -- Gastrointestinal tract / Mark A. Jepson -- Reproductive toxicity / Karin Sørig Hougaard and Luisa Campagnolo -- Genotocicity and cancer / Shareen H. Doak, Ying Liu and Chunying Chen -- C. Biomedical applications of engineered nanomaterials. Diagnostic applications / Kalcheng and Zhen Cheng -- Therapeutic applications / Cyrill Bussy ... [et al.] -- Annex: synthesis of engineered nanomaterials / Muhammet S. toprak, Gulaim A. Seisenbaeva and Vadim G. Kessler.
  • 2017From: ScienceDirect
    Giuseppe Tridente.
    Introduction -- Kinases -- Kinase inhibitors -- Adverse events -- Imantinib -- Gefitinib -- Erlotinib -- Sorafenib -- Sunitinib -- Dasatinib -- Lapatinib -- Nilotinib -- Pazopanib -- Vandetanib -- Vemurafenib -- Crizotinib -- Ruxolitinib -- Axitinib -- Bosutinib -- Regorafenib -- Cabozantinib -- Ponatinib -- Dabrafenib -- Trametinib -- Afatinib -- Idelaisib -- Ibrutinib -- Overview -- Conclusion and perspectives.
  • 2014From: Springer
    Giuseppe Tridente.
    This monograph gathers and evaluates data on adverse events (AEs) associated specifically with those 'biomedicines' - monoclonal antibodies, fusion proteins, and cytokines - that have recently entered therapeutic use in humans. All AEs observed when using each member of this new drug class are covered, with a view to improving understanding of pathogenesis, facilitating prevention, monitoring, and control, and contributing to the development of better drugs that provide benefits while minimizing risk. Further aspects here examined include the role of drug mechanisms of action and immunogenicity in relation to AEs outcome and induction of systemic syndromes. Additional data on AEs in off-label treatments are also considered. Electronic data sheets, downloadable from the Springer Extra Materials platform, include more detailed safety data as well as additional basic information on product characteristics, pre- and post-marketing AEs classified according to frequency, and system/organ targeting. Data on excipients and selected information on drug interactions and associations are also provided. Adverse Events with Biomedicines: Prevention Through Understanding will serve as a detailed, practical guideline to this important new area, which demands the attention of clinicians, immunologists, oncologists, allergologists, public health professionals, and drug companies.
  • Robert Boice.
    PrintStatus: Not Checked OutLane Catalog Record
    Nihil nimus is a guide to the start of a successful academic career. As its title suggests (nothing in excess), it advocates moderation in ways of working.--From publisher description.
  • 2013From: Springer
    Richard Colgan.
    Part I. Inspirational Perspectives from History -- -- Introduction -- Ancient times -- Chinese and medieval medicine -- The twentieth century -- Modern masters -- -- Part II. Practical Advice for the Modern-Day Healer -- -- Survival tips for the younger clinician -- Civility -- Lessons learned from private practice -- A doctor's journal -- Heal thyself -- The healer.
  • 2009From: Springer
    Richard Colgan.
  • 2013From: ScienceDirect
    edited by Devanand Sarkar and Paul B. Fisher.
    Ch. 1. AEG-1/MTDH/LYRIC, the beginning: initial cloning, structure, expression profile, and regulation of expression -- Ch. 2. AEG-1/MTDH/LYRIC: clinical significance -- Ch. 3. AEG-1/MTDH/LYRIC: signaling pathways, downstream genes, interacting proteins, and regulation of tumor angiogenesis -- Ch. 4. Pleiotropic roles of AEG-1/MTDH/LYRIC in breast cancer -- Ch. 5. Drug resistance mediated by AEG-1/MTDH/LYRIC -- Ch. 6. The role of AEG-1/MTDH/LYRIC in the pathogenesis of central nervous system disease -- Ch. 7. AEG-1/MTDH/LYRIC in liver cancer -- Index.
  • 2013From: CRCnetBASE
    edited by Lev S. Ruzer, Naomi H. Harley.
    Ch. 1. Medical and pharmaceutical aerosols / Stephen R. Marek ... [et al.] -- ch. 2. Breathing zone exposure assessment / Charles E. Rodes and Jonathan W. Thornburg -- ch. 3. Mechanisms of particle deposition / Jacky A. Rosati, Kristin K. Isaacs, and Ted B. Martonen -- ch. 4. Aerosol dose / Lev S. Ruzer, Michael G. Apte, and Richard G. Sextro -- ch. 5. Modeling deposition of inhaled particles / Kristin K. Isaacs, Jacky A. Rosati, and Ted B. Martonen -- ch. 6. Aerosol chemistry and physics / Lara A. Gundel and Hugo Destaillats -- ch. 7. Chemical analyses of particle filter deposits / Judith C. Chow and John. G. Watson -- ch. 8. Health effects of ambient ultrafine particles / Beverly S. Cohen -- ch. 9. Nanoparticle cell penetration / Steven M. Hankin and Craig A. Poland -- ch. 10. High aspect ratio nanomaterials : characterization and toxicology / Steven M. Hankin and Craig A. Poland -- ch. 11. Research and development of a new safe form of drugs / T.G. Tolstikova ... [et al.] -- ch. 12. Bioaerosols / Janet M. Macher ... [et al.] -- ch. 13. Aerosols, global climate, and the human health co-benefits of climate change mitigation / George D. Thurston and Michelle L. Bell -- ch. 14. Health effects of metals in ambient air particulate matter / Morton Lippmann -- ch. 15. Radioactive aerosols / Lev S. Ruzer -- ch. 16. Unattached fraction of radon progeny as an experimental tool in the assessment of the risk of nanoparticles / Lev S. Ruzer -- ch. 17. Filtration and sampling of aerosols by fibrous filters / A.K. Budyka, A.A. Kirsch, and B.I. Ogorodnikov -- ch. 18. Radioactive aerosols of Chernobyl accident / A.K. Budyka and B.I. Ogorodnikov -- ch. 19. Classical nucleation theory : account of dependence of the surface tension on curvature and translation-rotation correction factor / S.V. Vosel ... [et al.] -- ch. 20. Radioactive aerosol standards / Lev S. Ruzer ... [et al.] -- ch. 21. Radon and thoron in the environment : concentrations and lung cancer risk / Naomi H. Harley -- ch. 22. Risk from inhalation of the long-lived radionuclides uranium, thorium, and fallout plutonium in the atmosphere / Isabel M. Fisenne -- ch. 23. Health effects of aerosols : mechanisms and epidemiology / Ira B. Tager.
  • 2010From: ClinicalKey
    editors, Elizabeth J. Hall-Findlay, Gregory R.D. Evans ; video editor, Kenneth K. Kim.
    Drs. Hall-Findlay and Evans' new Aesthetic and Reconstructive Surgery of the Breast has a purely surgical focus that covers the full scope of breast surgery. Coverage of hot topics includes new implant types, gel implants, fat injections to the breast for aesthetic enhancement, and fat injections for reconstruction. The book is organized into seven sections including reduction, mastopexy, augmentation, and more. Expert, international contributors deliver practical advice on the latest techniques, with a special emphasis on what can go wrong and how to avoid it. This full-color, templated reference comes with case studies and 16 video clips (both on web and on DVD) with approximately three hours of footage demonstrating key procedures. Video coverage includes form-stable high cohesive silicone gel implants, short scar with inferior pedicle, and sub-fascial breast augmentation. Expert Consult access enables you to search full text online and download images. Get practical advice on handling problems that occur in both reconstructive and aesthetic surgery Study various operative steps in depth with real-life clinical detail Avoid and/or deal with complications by referencing case examples and analyses with expert international counsel Watch the techniques first-hand with videos online and on the accompanying DVD, and watch experts performing the procedures Search the text's full content electronically, or download images and video for teaching purposes.
  • 2011From: Springer
    Lucian Fodor, Yehuda Ullmann, Monica Elman.
    Skin anatomy -- Light tissue interactions -- Intense pulsed light safety: legal issues -- How to organize the IPL treatment room -- Patient selection -- Skin photorejuvenation -- Hair removal -- IPL treatment for vascular lesions -- Complications.
  • 2009From: ClinicalKey
    edited by Louis P. Bucky, A. Aldo Mottura.
    Pre-operative evaluation, preparation and education of the breast augmentation patient -- Breast augmentation: incision selection -- Subpectoral approach for primary breast augmentation -- Saline implants: indications, techniques and precautions -- Silicone implants -- Semi-cohesive gel implants -- Subfascial transaxillary breast augmentation -- Secondary augmentation -- Breast reconstruction and augmentation using pre-expansion and autologous fat transplantation -- Tubular breasts -- Mastopexy: augmentation -- Periareolar/vertical/small horizontal scars -- Circumvertical breast reduction technique -- Vertical breast reduction -- Vertical mammaplasty -- No vertical scar breast reduction/mastopexy -- Breast shaping in the massive weight loss patient -- Complications in breast augmentation: maximizing patient outcomes with some surgical solutions to common problems.
  • 2010From: ClinicalKey
    [edited by] Marian Cantisano-Zilkha, Alessandra Haddad.
    Overview of the aesthetic approach -- Combining non-invasive therapies -- Skincare -- Chemical peels -- Lasers and intense light sources -- Photodynamic treatment -- Skin tightening devices -- Botulinum toxin for oculofacial aesthetic rejuvenation -- Facial fillers and volumizers -- Fat transfer -- Dark circles: a combination approach -- Minimally invasive laser lipolysis for facial and neck rejuvenation -- Mesotherapy -- Carbon dioxide therapy: face and body rejuvenation -- Cosmetic dentistry of the perioral area: the odontological point of view -- Importance of aesthetician in a cosmetic practice -- From the inside out: a psychotherapist's views on aesthetic enhancement -- Future of oculofacial rejuvenation: a perspective.
  • 2009From: ClinicalKey
    [edited by] Sherell J. Aston, Douglas S. Steinbrech, Jennifer L. Walden.
    Office practice of plastic surgery -- Clinical photography for the aesthetic patient -- Anesthesia in aesthetic surgery -- Postoperative nausea and vomiting -- Patient safety in aesthetic surgery -- Facelift anatomy, SMAS, retaining ligaments and facial spaces -- Facelift with SMAS technique and FAME -- Facelift with SMAS technique and FAME -- Short scar facelift -- Foundation facelift -- The "High SMAS" facelift technique -- MACS facelift -- The multi-vectored rhytidoplasty -- The male facelift -- Endoscopic mid and lower face rejuvenation -- Endoscopic facial rejuvenation -- Facial rejuvenation in non-Caucasians -- Aesthetic facial microsurgery -- Midface lift -- Deep plane procedures in the neck -- Treatment of the male neck -- Managing submandibular glands -- Non-endoscopic limited incision browlift -- Coronal browlift -- Endoscopic browlift with internal fixation -- Transblepharoplasty browlift -- Suture suspension for face and neck -- Suture suspension for brow and upper face -- Conventional upper and lower blepharoplasty -- Lateral canthal suspension techniques -- Lid-cheek blending: the tear trough deformity -- Tarsal strip canthoplasty -- Blepharoplasty in the East Asian patient -- Treatment of blepharoplasty complications -- Autologous contouring the lower face -- Alloplastic chin augmentation -- Primary closed rhinoplasty -- Primary open rhinoplasty -- Secondary rhinoplasty -- Nasal tip grafting with an "anatomic tip graft" and sizers -- Nasal tip grafting with an "anatomic tip graft" and sizers -- Correction of the deviated septum -- The ethnic rhinoplasty -- The Asian rhinoplasty -- Correcting the cleft lip nose -- Primary otoplasty and reconstruction -- Traditional inverted-T breast reduction -- Mastopexy with and without augmentation -- Pitanguy breast reduction -- Medial pedicle vertical mammaplasty -- Periareolar Benelli mastopexy and reduction: The "Round Block" -- Breast implants: background, safety and general considerations -- Breast augmentation -- The dual plane approach to breast augmentation -- Cohesive gel breast augmentation -- Difficult breast augmentations -- Breast reconstruction -- Nipple - areola reconstruction -- Pure aspiration lipoplasty -- Complications and corrections of lipoplasty -- New concepts in fat grafting -- Lipoabdominoplasty: Saldanha's technique -- Lipoabdominoplasty: Advanced techniques and technologies -- Non-surgical ultrasonic lipoplasty -- Ultrasound assisted liposuction -- Abdominoplasty techniques -- Brachioplasty -- Belt lipectomy: Lower body lift -- High lateral tension abdominoplasty -- Gluteal augmentation -- Botox® for face, neck and brow -- Lip augmentation -- Structural fat augmentation of the face and hands -- Hyaluronic acid injectable filler -- Non-hyaluronic acid fillers for facial augmentation -- Laser resurfacing -- Fractional resurfacing -- Total facial alloplastic augmentation -- Chemical peels and dermabrasion.
  • 2016From: Springer
    Alberto Di Giuseppe, Melvin A. Shiffman, editors.
    This comprehensive book covers anatomy, recent techniques, postoperative care, possible complications, and outcomes in aesthetic surgery of the abdomen. The extensive section on aesthetic procedures includes many important innovations in abdominoplasty. Detailed consideration is also given to the various potential complications, with guidance on their prevention, diagnosis, and management. The book is written by acknowledged experts in the topics on which they write. It will be of value for residents and fellows and more experienced surgeons in the fields of plastic surgery, general surgery, cosmetic surgery, and general surgery.
  • 2016From: Thieme-Connect
    [edited by] Hong Ryul Jin.
  • 2012From: ClinicalKey
    [edited by] Bahman Guyuron, Brian M. Kinney.
    Patient Assessment -- Skin Care Including Chemical Peeling -- Non-surgical Facial Rejuventation with Fillers -- Botulinum Toxin -- Laser Facial Resurfacing and Dermabrasion -- Management of Alopecia -- Forehead Rejuvenation -- Periorbital Rejuvenation -- Facelift with SMAS Flaps -- Neck Rejuvenation -- Primary Rhinoplasty -- Secondary Rhinoplasty -- Genioplasty -- Aesthetic Contouring of the Craniofacial Skeleton -- Augmentation of Facial Structures with Autologous Fat -- Breast Augmentation -- Breast Reduction -- Mastopexy -- Liposculpture -- Abdominoplasty -- Bodylifts and Post Massive Weight Loss Body Contouring -- Surgical Management of Migraine Headaches.
  • 2016From: Springer
    Bariş Çakir.
  • 2015From: Springer
    Toma T. Mugea, Melvin A. Shiffman, editors.
    This book covers all aspects of aesthetic breast surgery in an instructive, step-by-step format. The descriptions of procedures are completely up to date, encompassing newly introduced techniques and recent modifications of established techniques. Individual parts of the book are devoted to breast augmentation, mastopexy, and breast reduction. Detailed consideration is also given to risks and complications, with guidance on their avoidance and the treatment of complications. In addition, anatomy, anesthesia, and a range of miscellaneous procedures applicable in specific circumstances are all well covered. The authors are acknowledged experts in their fields who draw on a wealth of experience in describing and illustrating their personally favored techniques. Aesthetic Surgery of the Breast will be an ideal reference for both students (residents and fellows) and practicing cosmetic, plastic, and general surgeons.
  • 2007From: Springer
    Dimitrije E. Panfilov (ed.).
  • 2008From: Ovid
    [edited by] Pearl E. Grimes ; associate editors, Teresa Soriano, Doris M. Hexsel, Jenny Kim.
  • 2010From: Karger
    volume editor, Rainer Staudenmaier.
    History of auricular reconstruction / Weerda, H. -- State-of-the-art autogenous ear reconstruction in cases of microtia / Firmin, F. -- Ear reconstruction with porous polyethylene implants / Berghaus, A. ... [et al.] -- Auricular prostheses / Federspil, P.A. -- Combined aesthetic and functional reconstruction of ear malformations / Kiefer, J., Staudenmaier, R. -- Combined reconstruction of congenital auricular atresia and severe microtia / Siegert, R. -- Ear reconstruction through tissue engineering / Haisch, A. -- Customized tissue engineering for ear reconstruction / Staudenmaier, R. ... [et al.].
  • 2008From: Springer
    P. Colm Malone, Paul S. Agutter.
  • 2008From: Springer Protocols
    edited by Michael Zachariou.
    Affinity chromatography : history, perspectives, limitations, and prospects / Ana Cecília A. Roque and Christopher R. Lowe -- Immobilized metal ion affinity chromatography of native proteins / Adam Charlton and Michael Zachariou -- Affinity precipitation of proteins using metal chelates / Ashok Kumar, Igor Yu. Galaev, and Bo Mattiasson -- Immunoaffinity chromatography / Stuart R. Gallant, Vish Koppaka, and Nick Zecherle -- Dye ligand chromatography / Stuart R. Gallant, Vish Koppaka, and Nick Zecherle -- Purification of proteins using displacement chromatography / Nihal Tugcu -- Rationally designed ligands for use in affinity chromatography : an artificial protein L / Ana Cecília A. Roque and Christopher R. Lowe -- Phage display of peptides in ligand selection for use in affinity chromatography / Joanne L. Casey, Andrew M. Coley, and Michael Foley -- Preparation, analysis, and use of an affinity adsorbent for the purification of GST fusion protein / Gareth M. Forde -- Immobilized metal ion affinity chromatography of histidine-tagged fusion proteins / Adam Charlton and Michael Zachariou -- Methods for the purification of HQ-tagged proteins / Becky Godat ... [et al.] -- Amylose affinity chromatography of maltose-binding protein : purification by both native and novel matrix-assisted dialysis refolding methods / Leonard K. Pattenden and Walter G. Thomas -- Methods for detection of protein-protein and protein-DNA interactions using HaloTag / Marjeta Urh ... [et al.] -- Site-specific cleavage of fusion proteins / Adam Charlton -- The use of TAGZyme for the efficient removal of N-terminal his-tags / José Arnau ... [et al.] -- Affinity processing of cell-containing feeds using monolithic macroporous hydrogels, cryogels / Igor Yu. Galaev and Bo Mattiasson -- Monolithic bioreactors for macromolecules / Mojca Benčina ... [et al.] -- Plasmid DNA purification via the use of a dual affinity protein / Gareth M. Forde -- Affinity chromatography of phosphorylated proteins / Grigoriy S. Tchaga -- Protein separation using immobilized phospholipid chromatography / Tzong-Hsien Lee and Marie-Isabel Aguilar -- Analysis of proteins in solution using affinity capillary electrophoresis / Niels H.H. Heegaard, Christian Schou, and Jesper Østergaard.
  • 2015From: Springer Protocols
    edited by Senta Reichelt, Leibniz-Institut für Oberflächenmodifizierung, Leipzig, Germany.
    Affinity chromatography : a historical perspective -- Protein purification by amniosquarylium cyanine dye-affinity chromatography -- One-step purification of phosphinothricin acetyltransferase using reactive dye-affinity chromatography -- Antibody purification from human plasma by metal-chelated affinity membranes -- Specific recognition of supercoiled plasmid DNA by affinity chromatography using a synthetic aromatic ligand -- Cell affinity separations on microfluidic devices -- Aptamer-modified magnetic beads in affinity separation of proteins -- The Strep-tag system for one-step affinity purification of proteins from mammalian cell culture -- Robotic high-throughput purification of affinity-tagged recombinant proteins -- Macroporous silica particles derivatized for enhanced lectin affinity enrichment of glycoproteins -- Immobilized magnetic beads-based multi-target affinity selection coupled with HPLC-MS for screening active compounds from traditional Chinese medicine and natural products -- Mixed-bed affinity chromatography : principles and methods -- Preparation and characterization of fluorophenylboronic acid-functionalized affinity monolithic columns for the selective enrichment of cis-diol-containing biomolecules -- Introduction to macroporous cryogels -- Cryogels with affinity ligands as tools in protein purification -- Direct capture of His6-tagged proteins using megaporous cryogels developed for metal-ion affinity chromatography -- Ni(II) chelated IDA functionalized poly(HEMA-GMA) cryogels for urease adsorption -- A novel chromatographic media : histidine-containing composite cryogels for HIgG separation from human serum -- Molecularity imprinted cryogels for human serum albumin depletion -- Interpenetrating polymer network composite cryogels with tailored porous morphology and sorption properties -- Analysis of drug-protein interactions by high-performance affinity chromatography : interactions of sulfonylurea drugs with normal and glycated human serum albumin -- Accurate protein-peptide titration experiments by nuclear magnetic resonance using low-volume samples -- Characterization of the binding strengths between boronic acids and cis-diol-containing biomolecules by affinity capillary electrophoresis -- Determination if the kinetic rate constant of cyclodextrin supramolecular systems by high-performance affinity chromatography -- Molecular modeling of the affinity chromatography of monoclonal antibodies.
  • Adelle Simmons, Jessamy Taylor, Kenneth Finegold, Robin Yabroff, Emily Gee, and Andre Chappel.
    The Affordable Care Act promotes better health for women through the law's core tenets of access, affordability, and quality. For example, the law's provisions have expanded coverage through the Health Insurance Marketplaces and Medicaid expansions; made coverage more affordable through premium tax credits and by eliminating gender differences in premiums in the individual and small-group insurance markets; and improved quality of coverage by eliminating lifetime and annual dollar limits on Essential Health Benefits and requiring coverage of recommended preventive services and maternity care. Continued implementation of the Affordable Care Act will play a significant role in promoting the health and well-being of women across the lifespan. This report is organized into three sections that describe how health care access, affordability, and quality of care have improved for women since enactment of the Affordable Care Act.
  • 2014From: Springer
    Harry P. Selker, June S. Wasser, editors.
    This book examines the landmark 2010 Patient Protection and Affordable Care Act (ACA) from the perspective that health policy innovation is translational research directed at improving health. It delineates a new perspective about the creation and potential impact of the ACA and guides the development of health policy that is supported by best evidence that, in turn, transforms into practice, policy, and public benefit. Told by those involved in the creation and implementation of the ACA, the book reviews the history and impact of this ground-breaking legislation and recommends priorities, objectives, and next steps for translational research as the ACA is implemented. Featuring contributions from nationally renowned leaders in healthcare policy, this book adds to the public conversation about the ACA and its role in shaping health policy and contributes to a more realistic, nuanced, and productive understanding of this ground-breaking legislation by physicians, policy makers, and the public. It also provides a framework for next steps in continuing to improve U.S. health policy.
  • by Kelsey Avery, Kenneth Finegold, and Amelia Whitman.
    Historic gains in health insurance coverage have been achieved since the implementation of the Affordable Care Act (ACA). Individuals and families of all income levels, age groups, races and ethnicities, and urban and rural areas have seen substantial reductions in uninsured rates. Coverage expansion provisions of the ACA (i.e., the Health Insurance Marketplace and Medicaid expansion) and reforms in the private market, such as allowing young adults to remain on their parents' plan until age 26 and requiring insurers to cover individuals with pre-existing health conditions, have worked in concert to reduce the national uninsured rate to a historic low of 8.6 percent. To date, 20 million individuals have gained health coverage as a result of the ACA . This brief, uses new and previously published estimates from the National Health Interview Survey to examine gains in health insurance coverage for non-elderly adults from 2010 to 2015. It also provides estimates of the uninsured rate over time by income, race, state Medicaid expansion status, age, and urban and rural residence (see Appendix Table 2 for additional demographic categories).
  • William A. Haseltine.
    The Singapore healthcare system : an overview -- High quality, low cost -- Helping patients pay -- Controlling costs -- Financing -- Design and infrastructure -- Investing in the future through medical education and research -- Facing the future.
  • by Janet Viveiros.
    This report examines several ways in which health care changes created by the ACA, and other health care reform initiatives, create the potential for affordable housing providers to collaborate with health care providers, insurers, and other institutions to support the wellbeing of low-income individuals and families.
  • 2010From: Springer
    Donna Hubbard McCree, Kenneth Terrill Jones, Ann O'Leary, editors.
    The HIV/AIDS epidemic is burgeoning among African American men and women. Despite comprising only 13 percent of the population, 50 percent of new HIV diagnoses in 2004 were among African Americans. Among women and men who have sex with men (MSM), African Americans are grossly disproportionately affected by this epidemic, and this trend shows no sign of abating. This book seeks to explore some of the contextual factors that contribute to this disparity as well as ways to intervene to slow the growth of the epidemic in the U.S. This volume will focus on the history and context of HIV/AIDS in African Americans and interventions targeting specific subpopulations including adolescents, heterosexual men and women, men who have sex with men, incarcerated populations, and injection drug users. Context chapters will focus on specific contextual and structural issues related to HIV/AIDS transmission and prevention in African Americans including disparities in incarceration, racism, economic issues and substance abuse. Intervention chapters will focus on best-evidence and promising-evidence based interventions targeting HIV prevention in African Americans. These chapters will address the latest in intervention strategies, program evaluation, cost effectiveness and qualitative research methods and will include risk reduction, risk assessment, and testing and counseling.
  • 2016From: Cambridge
    edited by Patrick Low, Chiedu Osakwe, Maika Oshikawa.
    Introduction and overview / Patrick Low, Chiedu Osakwe and Maika Oshikawa -- African Union priorities in the WTO / Fatima Haram Acyl -- Economic diversification in Africa's number one economy / Okechukwu E. Enelamah -- Trade, investment and development / Rob Davies -- Integration into regional and global value chains : how is it done? / Joshua Setipa -- From Marrakesh to Nairobi : a force for the world trading system : from the past twenty years to the next twenty years / Moulay Hafid El Alamy -- Building capacity in Africa to facilitate integration into global value chains : contributions from the ITC / Arancha Gonzalez -- Investment and trade rules : increasing the stock of African foreign direct investment flows / Joakim Reiter -- Deepening African integration : intra-African trade for development and poverty reduction / Anabel Gonzalez -- Rising Africa in world trade? A story of traditional commodities and new products / Michael Finger -- Trade policy trends in Africa : empirical evidence from twenty years of WTO trade policy reviews / Maika Oshikawa, Ukamaka Anaedu and Vicky Chemutai -- Preferential trade agreements in Africa : lessons from the tripartite free trade agreements and an African continent-wide FTA / Stephen Karingi, Ottavia Pesce and Simon Mevel -- African trade integration and international production networks / Bernard Hoekman -- Implementing trade facilitation reform in Africa / Marcus Bartley Johns, Christina Busch and Gerard McLinden -- Trade rules, industrial policy and competitiveness : implications for Africa's development / Chiedu Osakwe -- WTO accessions, reforms and competitiveness : lessons for Africa / Alexei P. Kireyev -- Driving economic growth through trade policy reforms and investment attraction in the open world economy : the experience of China / Yuan Yuan -- Conclusions / Patrick Low, Chiedu Osakwe and Maika Oshikawa.
  • 2013From: IngentaConnect
    edited by Angelique Richardson.
    1. Love and hatred are common to the whole sensitive creation: animal feeling in the century before Darwin -- 2. 'The Book of the Season': the conception and reception of Darwin's Expression -- 3. The backbone shiver: Darwin and the arts -- 4. Becoming an animal: Darwin and the evolution of sympathy -- 5. George Eliot, G.H. Lewes, and Darwin: animals, emotions, and morals -- 6. Between medicine and evolutionary theory: sympathy and other emotional investments in life writings by and about Charles Darwin -- 7. From entangled vision to ethical engagement: Darwin, affect, and contemporary exhibition projects -- 8. Reckoning with the emotions: neurological responses to the theory of evolution, 1870-1930 -- 9. Darwin's changing Expression and the making of the modern state -- 10. Calling the wild: selection, domestication, and species -- 11. The development of emotional life -- Afterword. The emotional and moral lives of animals: what Darwin would have said -- Index.
    Also available: Print – 2013
  • 2013From: ProQuest Ebook Central
    Michael J. Hyde and James A. Herrick, editors.
    Faith in science : professional and public discourse on regenerative medicine / Tristan Keys, Nancy M. P. King, and Anthony Atala -- From Arrowsmith to Atwood : how did we come to disrespect science? / Ronald M. Green -- The "warfare" of science and religion and science's ethical profile / Thomas M. Lessl -- Is there a human nature? : an argument against modern excarnation / Jean Bethke Elshtain -- Crossing frontiers of science : trespassing into a godless space, or, Fulfilling our manifest destiny / Leah Ceccarelli -- The angels and devils of representing Prozac / Tod Chambers -- "Leave your medicine outside" : bioethics, spirituality, and the rhetoric of Appalachian serpent handlers / Bill J. Leonard -- Biovaluable stories and a narrative ethics of reconfigurable bodies / Arthur W. Frank -- Blacks and the language of their biotechnological future / Ezra E. H. Griffith -- Bioethics, economism, and the rhetoric of technological innovation / Howard Brody -- Technologies of the self at the end of life : pastoral power and the rhetoric of advance care planning / Lisa Kernen -- Suffering and the rhetoric of care / Judy Segal.
  • Larissa N. Heinrich.
    "In 1739 China's emperor authorized the publication of a medical text that included images of children with smallpox to aid in the diagnosis and treatment of the disease. Those images made their way to Europe, where they were interpreted as indicative of the ill health and medical backwardness of the Chinese. In the mid-nineteenth century, the celebrated Cantonese painter Lam Qua collaborated with the American medical missionary Peter Parker in the creation of portraits of Chinese patients with disfiguring pathologies, rendered both before and after surgery. Europeans saw those portraits as evidence of Western medical prowess. Within China, the visual idiom that the paintings established influenced the development of medical photography. In The Afterlife of Images, Larissa N. Heinrich investigates the creation and circulation of Western medical discourses that linked ideas about disease to Chinese identity beginning in the eighteenth century." "Combining literary studies, the history of science, and visual culture studies, Heinrich analyzes the rhetoric and iconography through which medical missionaries transmitted to the West an image of China as "sick" or "diseased" She also examines the absorption of that image back into China through missionary activity, through the earliest translations of Western medical texts into Chinese, and even through the literature of Chinese nationalism. Heinrich argues that over time "scientific" Western representations of the Chinese body and culture accumulated a host of secondary meanings, taking on an afterlife with lasting consequences for conceptions of Chinese identity in China and beyond its borders."--Jacket.
  • Crystal R. Emery.
    PrintStatus: Not Checked OutLane Catalog Record
  • Allen M. Hornblum, Judith L. Newman, and Gregory J. Dober.
    "The sad history of young children, especially institutionalized children, being used as cheap and available test subjects - the raw material for experimentation - started long before the atomic age and went well beyond exposure to radioactive isotopes. Experimental vaccines for hepatitis, measles, polio and other diseases, exploratory therapeutic procedures such as electroshock and lobotomy, and untested pharmaceuticals such as curare and thorazine were all tested on young children in hospitals, orphanages, and mental asylums as if they were some widely accepted intermediary step between chimpanzees and humans. Occasionally, children supplanted the chimps. Bereft of legal status or protectors, institutionalized children were often the test subjects of choice for medical researchers hoping to discover a new vaccine, prove a new theory, or publish an article in a respected medical journal. Many took advantage of the opportunity. One would be hard-pressed to identify a researcher whose professional career was cut short because he incorporated week-old infants, ward-bound juvenile epileptics, or the profoundly retarded in his experiments. In short, involuntary, non-therapeutic, and dangerous experiments on children were far from an unusual or dishonorable endeavor during the last century."--Provided by publisher.
  • 2015From: Springer
    Alessandro Plebani, Vassilios Lougaris, editors.
    This book provides an updated overview of agammaglobulinemia, a rare form of primary immunodeficiency which is considered the prototype of the congenital humoral defects, and which is characterized by the absence of peripheral B cells and very low serum immunoglobulin levels. The book opens by discussing the highly orchestrated early B cell development in the bone marrow and the genes involved based on both human and animal models. The pathogenesis and clinical presentation of X-linked agammaglobulinemia, caused by mutations in the BTK (Bruton's tyrosine kinase) gene, are then presented in detail, followed by descriptions of the clinical manifestations and molecular basis of the less frequent autosomal recessive and autosomal dominant forms of agammaglobulinemia. Patients' management in terms of respiratory complications, gammaglobulin replacement therapy and the potential value of novel experimental therapeutic strategies are discussed. The book's closing chapters offer a comprehensive and updated description of mutations in the BTK gene, and the expression and function of BTK in cells other than B cells.
  • 2008From: Springer
    edited by Carlo A.P. Cavallotti, Luciano Cerulli.
    Aging as risk factor in eye disease -- Age-related changes of the eyelid -- Aging effects on the optics of the eye -- Aging of the cornea -- The aging of the human lens -- The extracellular matrix of the aged human trabecular meshwork: changes of glucosaminoglycans -- Glial and mobile cells in the iris of the aging human eye -- Age-related diseases of the vitreous -- Age-related changes and/or diseases in the human retina -- Aging of the retinal pigmented epithelium -- The aging of the choroid -- Age-related macular degeneration I: types and future directions -- Age-related macular degeneration II: idiopathic macular holes -- Age-related macular degeneration III: epiretinal membranes -- Macular degeneration: ultrastructural age-related changes -- Non-exudative macular degeneration and management -- Treatment of intraocular pressure in elderly patients -- Aging of the lachrymal [lacrimal] gland -- The world according to blink: blinking and aging -- Age-related changes in the oculomotor system -- Rehabilitation of low vision in aged people -- Many suggestions to protect the eyes in aging people.
    Also available: Print – 2008
  • 2011From: Springer
    Allen C. Ho, Carl D. Regillo, editors.
    1. Genetics of Age-Related Macular Degeneration / Daniel T. Kasuga, Yuhong Chen, and Kang Zhang -- 2. Modifiable Risk Factors of Age-Related Macular Degeneration / Hanna R. Coleman -- 3. Diagnosis of Age-Related Macular Degeneration / Jonathan Jonisch and Gaurav Shah -- 4. Fundus Imaging of Age-Related Macular Degeneration / Allen Chiang, Andre J. Witkin, Carl D. Regillo, and Allen C. Ho -- 5. Therapy of Nonexudative Age-Related Macular Degeneration / Annal D. Meleth, Veena R. Raiji, Nupura Krishnadev, and Emily Y. Chew -- 6. Management of Neovascular AMD / Fernando M. Penha and Philip J. Rosenfeld -- 7. Combination Therapy with Ocular Photodynamic Therapy for Age-Related Macular Degeneration / Nathan Steinle and Peter K. Kaiser -- 8. The Future of Non-neovascular Age-Related Macular Degeneration / Ketan Laud, Sri Krishna Mukkamala, Claudia Brue, and Jason S. Slakter -- 9. The Future of Neovascular Age-Related Macular Degeneration / Chirag P. Shah and Jeffrey S. Heier -- 10. The Economics of Age-Related Macular Degeneration / Gary C. Brown, Melissa M. Brown, Heidi B. Lieske, Philip A. Lieske, and Kathryn Brown.
  • edited by Jennifer I. Lim.
    PrintStatus: Not Checked OutLane Catalog Record
    Histopathology of age-related macular degeneration / Shin J. Kang and Hans E. Grossniklaus -- Immunology of age-related macular degeneration / Karl G. Csaky and Scott W. Cousins -- Genetics of age-related macular degeneration / Jennifer R. Chao, Amani A. Fawzi, and Jennifer I. Lim -- Risk factors for age-related macular degeneration and choroidal neovascularization / Kah-Guan Au Eong ... [et al.] -- Choroidal neovascularization / Frances E. Kane and Peter A. Campochiaro -- Non-exudative age-related macular degeneration / Neelakshi Bhagat and Christina J. Flaxel -- Geographic atrophy / Sharon D. Solomon and Janet S. Sunness -- Exudative (neovascular) age-related macular degeneration / Jennifer I. Lim and Jerry W. Tsong -- Indocyanine green angiography in age-related macular degeneration / Scott C.N. Oliver ... [et al.] -- Optical coherence tomography in the evaluation and management of age-related macular degeneration / David Eichenbaum and Elias Reichel -- Quantitative retinal imaging / Daniel D. Esmaili ... [et al.] -- Fundus autofluorescence in age-related macular degeneration / Rishi P. Singh, Jeffrey Y. Chung, and Peter K. Kaiser -- Laser photocoagulation for choroidal neovascularization / Catherine Cukras and Stuart L. Fine -- Photocoagulation of AMD-associated CNV feeder vessels: an optimized approach / Robert W. Flower -- Photodynamic therapy / ATul Jain, Darius M. Mosfeghi, and Mark S. Blumenkranz -- Radiation treatment in age-related macular degeneration / Christina J. Flaxel and Paul T. Finger -- Anti-VEGF drugs and clinical trials / Todd R. Klesert, Jennifer I. Lim, and Phillip J. Rosenfeld -- Laser prophylaxis for age-related macular degeneration / Jason Hsu and Allen C. Ho -- Macular translocation / Kah-Guan Au Eong ... [et al.] -- Age-related macular degeneration : use of adjuncts in surgery and novel surgical approaches / Richard Scartozzi and Lawrence P. Chong -- Clinical consideration for visual rehabilitation / Susan A. Primo -- Retinal prostheses : a possible treatment for end-stage age-related macular degeneration / Thomas M. O'Hearn ... [et al.] -- Retinal pigment epithelial cell transplantation and macular reconstruction for age-related macular degeneration / Lucian V. Del Priore, Henry J. Kaplan, and Tongalp H. Tezel -- Clinical research trials / A. Frances Walonker and Kenneth R. Diddie.
  • 2013From: Springer
    edited by Frank G. Holz, Daniel Pauleikhoff, Richard F. Spaide, Alan C. Bird.
    pt. 1. Pathophysiology. Epidemiology of AMD / L. Ho, R. van Leeuwen, P. T. V. M. de Jong, J. R. Vingerling and C. C. W. Klaver -- Genetics / L. G. Fritsche, U. Friedrich and B. H. F. Wxeber -- Ageing of the Retina and Retinal Pigment Epithelium / M. E. Boulton -- The Complement System in AMD / P. Charbel Issa, N. V. Chong and H. P. N. Scholl -- Histopathology / A. Lommatzsch, S. Wasmuth, D. Pauleikhoff, F. G. Holz and A. C. Bird -- pt. 2. Clinical Manifestations. Early AMD / M. Dietzel, D. Pauleikhoff, F. G. Holz and A. C. Bird -- Clinical Manifestations of Choroidal Neovascularization in AMD / R. F. Spaide -- Geographic Atrophy / M. Fleckenstein, S. Schmitz-Valckenberg, J. S. Sunness and F. G. Holz -- pt. 3. Diagnostics. Fundus Imaging of AMD / R. F. Spaide -- Optical Coherence Tomography / S. Wolf -- Microperimetry / E. Midena and E. Pilotto -- pt. 4. Prophylaxis and Therapy. Nutritional Supplementation in AMD / A. D. Meleth, V. R. Raiji, N. Krishnadev and E. Y. Chew -- Laser Photocoagulation and Photodynamic Therapy / G. Soubrane -- Anti-VEGF Therapy: Basics and Substances / S. Grisanti, J. Lüke and S. Peters -- Anti-VEGF Therapy for AMD: Results and Guidelines / P. Mitchell and S. Foran -- Combination Therapies for the Treatment of AMD / M. Barakat, N. Steinle and P. K. Kaiser -- Treatment Approaches for Dry AMD / Z. Yehoshua and P. J. Rosenfeld -- Surgical Therapy / B. Kirchhof -- pt. 5. Rehabilitation. Reading with AMD / S. Trauzettel-Klosinski -- Low Vision Aids in AMD / K. Rohrschneider.
  • written by Siôn Eryl Jones; edited by Kathryn O'Neill.
    Research shows that for older people, cities present physical, social and economic barriers that prevent them realising their right to live in dignity and safety, or enjoying their surroundings. Groundbreaking initiatives to make cities more appropriate for older persons, such as the World Health Organization's Age-friendly Cities and Communities model, have led to improvements in a number of cities. Physical accessibility is absolutely essential, but thinking beyond this, what makes shared urban spaces and streets truly inclusive and liveable? What is the relationship between our health in older age and the physical, social and economic urban environment? What makes older people living in cities feel vulnerable to crime or disaster, and how does this affect their daily lives or the assistance they receive in times of crisis? These are some of the questions explored by this report. Focusing on low- and middle-income countries, this report aims to stimulate discussion about some of the actions that governments and city authorities can take to build truly inclusive cities.
  • 2007From: CRCnetBASE
    edited by Alan D. Dangour, Emily M.D. Grundy, and Astrid E. Fletcher.
    Nutritional concerns in old age / Lisette C.P.G.M. de Groot and Wija A. van Staveren -- Regular exercise, the best investment for our old age / Marion E.T. McMurdo -- Major eye diseases of later life: cataract and age related macular degeneration / Astrid E. Fletcher -- Reminiscence in everyday talk between older people and their carers: implications for the quality of life of older people in care homes / Fiona Wilson ... [et al.] -- Retention of cognitive function in old age: why initial intelligence is important / Lawrence J. Whalley -- Health inequalities in old age in Britain / Elizabeth Breeze -- Demographic change, family support, and ageing well: developed country perspectives / Emily M.D. Grundy -- Energy efficiency and health of older people / Paul Wilkinson -- Ageing, health, and welfare: an economic perspective / Charles Normand -- Methodological issues in assessing the cost-effectiveness of interventions to improve the health of older people / Damian Walker and Cristian Aedo -- Minimum income for healthy living: older people England 2005-2006 / Jerry Morris ... [et al.] -- Responding to increasing human longevity: policy, practice, and research / David Metz.
  • Alex Zhavoronkov.
    PrintStatus: Not Checked OutLane Catalog Record
    "Over the past twenty years, the biomedical research community has been delivering hundreds of breakthroughs expected to extend human lifespan beyond thresholds imaginable today. However, much of this research has not yet been adopted into clinical practice, nor has it been widely publicized. Just as the Internet and mobile communications were interwoven into our everyday lives over the past two decades, biomedicine will transform our society forever by allowing people to live longer and to continue working and contributing financially to the economy longer, rather than entering into retirement and draining the economy through pensions and senior healthcare. With a refocusing of medical national resources to regenerative medicine, old age will become a concept of the past, breakthroughs in regenerative medicine will continue, and an unprecedented boom to the global economy, with an influx of older able-bodied workers and consumers, will be a reality. A leading expert in aging research, author Alex Zhavoronkov provides a helicopter view on the progress science has already made, from repairing tissue damage to growing functional organs from a single cell, and illuminates the possibilities that the scientific and medical community will soon make into realities. The Ageless Generation is an engaging work that causes us to rethink our ideas of age and ability in the modern world"--Provided by publisher.
  • 2008From: Springer
    edited by Roberta Annicchiarico, Ulises Cortés, Cristina Urdiales, editors.
  • 2014From: Karger
    volume editors, Ladislas Robert, Tamas Fülöp.
    The Commitment of human cells to senescence / R. Holliday -- Evolutionary theories of aging can explain why we age / E. Le Bourg -- Control of cell replication during aging / A. Macieira-Coelho -- Cell senescence : role in aging and age-related diseases / J. Campisi, L. Robert, -- Aging of cell membranes : facts and theories / I. Zs.-Nagy -- Oxidative stress, mitochondrial dysfunction, and the mitochondria theory of aging / Y. Kong, S.E. Trabucco, H. Zhang -- Aging of connective tissues : experimental facts and theoretical considerations / J. Labat-Robert, L. Robert -- Aging of cell communication : loss of receptor function / L. Robert, T. Fulop -- On the immunological theory of aging / T. Fulop, J.M. Witkowski, G. Pawelec, C. Alan, A. Larbi -- Aging of the brain, dementias, role of infectious proteins : facts and theories / F. Morinet -- Aging as alteration / P.-A. Miquel -- Longevity and its regulation : centenarians and beyond / L. Robert, T. Fulop.
  • 2007From: Springer
    Robin Holliday.
    Longevity -- Body architecture -- Maintenance of the body -- Multiple causes -- The ancient origins of ageing -- Mice and men -- How many genes? -- The evolution of human longevity -- Myths of life extension -- Doctors' dilemma -- The modulation of longevity -- Ageing and the angels -- Longevity, population pressure and warfare -- Dialogue between life and death -- The road discovery -- Resolution of the paradox.
  • Danon, D.; Marois, M.; Shock, Nathan W.
    PrintStatus: Not Checked OutLane Catalog Record
    v. 1. Biology / edited by D. Danon, N.W. Shock, and M. Marois.--v. 2. Medicine / edited by A.J.J. Gilmore, A. Svanborg, M. Marois. Social sciences and social policy / edited by Walter M. Beattie, Jr., Jerzy Piotrowski, M. Marois.--v. 3. Behavioural sciences / edited by James E. Birren ... [et al.]. Conclusions and perspectives / edited by Maurice Marois.
  • 2010From: Springer
    Stephen Bondy, Kenneth Maiese, editors.
    Part 1. General Aspects of Aging -- Protein Redox-Regulation Mechanisms in Aging / Ufuk Çakatay -- Nitrosative Stress in Aging - Its Importance and Biological Implications in NF-κB Signaling / Predrag Ljubuncic, Einat Gochman and Abraham Z. Reznick -- Intervention with Multiple Micronutrients Including Dietary and Endogenous Antioxidants for Healthy Aging / Kedar N. Prasad -- Advanced Glycation End Products, RAGE, and Aging / Ravichandran Ramasamy, Loredana G. Bucciarelli, Shi Fang Yan and Ann Marie Schmidt -- Sirtuins and Mammalian Aging / Edward H. Sharman -- Estrogenic Modulation of Longevity by Induction of Antioxidant Enzymes / Jose Viña, Consuelo Borrás, Mari Carmen Gómez-Cabrera, Juan Gambini and Raul López-Grueso, et al. -- Mitochondrial Respiratory Function Decline in Aging and Life-Span Extension by Caloric Restriction / Shi-Bei Wu, Yu-Ting Wu, Chih-Hao Wang, Wan-Yu Lee and Yau-Huei Wei -- Methylglyoxal, Oxidative Stress, and Aging / Miklós Péter Kalapos, Kaushik M. Desai and Lingyun Wu -- Part 2. The Cardiovascular System -- Novel Strategies for Neurovascular Longevity During Aging / Kenneth Maiese, Zhao Zhong Chong, Jinling Hou and Yan Chen Shang -- Oxidative Stress in Vascular Disease / Isabelle Gorenne and Martin R. Bennett -- The Role of Mitochondrial Reactive Oxygen Species Formation for Age-Induced Vascular Dysfunction / Andreas Daiber, Joachim Kienhoefer, Rebecca Zee, Philip Wenzel and Volker Ullrich, et al. -- Aging, Oxidative Stress, and Cardiovascular Disorders / Yi Shi, Giovanni G. Camici and Thomas F. Lüscher -- Oxidative Stress, Aging, and Cardiovascular Disease / G. Riccioni, V. Sblendorio and N. D'Orazio -- Antioxidation in Prevention of Cardiovascular Diseases - An Effect of Polyphenols / Jun-ichi Suzuki, Mitsuaki Isobe, Ryuichi Morishita and Ryozo Nagai -- Vascular Aging and Oxidative Stress: Hormesis and Adaptive Cellular Pathways / Nathalie Thorin-Trescases and Eric Thorin -- Role of Oxidative Stress in Mediating Elevated Blood Pressure with Aging / Julio Sartori Valinotti, Licy Yanes and Jane F. Reckelhoff -- Part 3. The Nervous System -- Melatonin, Oxidative Stress, and the Aging Brain / Stephen Bondy and Edward H. Sharman -- The SAM Strain of Mice, a Higher Oxidative Stress, Age-Dependent Degenerative Disease, and Senescence Acceleration Model / Yoichi Chiba, Atsuyoshi Shimada and Masanori Hosokawa -- Antioxidants Combined with Behavioral Enrichment Can Slow Brain Aging / Elizabeth Head -- Role of Nitric Oxide in Neurodegeneration and Vulnerability of Neuronal Cells to Nitric Oxide Metabolites and Reactive Oxygen Species / Debomoy K. Lahiri, Chandramallika Ghosh, Jack T. Rogers, Stephen Bondy and Nigel H. Greig -- Free Radical-Mediated Damage to Brain in Alzheimer's Disease: Role of Acrolein and Preclinical Promise of Antioxidant Polyphenols / Charles Ramassamy, Madeleine Arseneault and Dang Thanh Nam -- An Epigenetic Model for Susceptibility to Oxidative DNA Damage in the Aging Brain and Alzheimer's Disease / Nasser H. Zawia and Fernando Cardozo-Pelaez.
  • 2007From: Springer
    Stephen J. Morewitz, Mark L. Goldstein.
  • 2015From: Karger
    volume editors, Anatoliy I. Yashin, Durham, NC, Michal Jazwinsk, New Orleans, La.
    Introduction to the theory of aging networks / Witten, T.M. -- Applications to aging networks / Wimble, C., Witten, T.M. -- Computational systems biology for aging research / Auley, M.T., Mooney, K.M. -- How does the body know how old it is? Introducing the epigenetic clock hypothesis / Mitteldorf, J. -- The great evolutionary divide : two genomic systems biologies of aging / Rose, M.R., Cabral, I.G., Philips, M.A., Rutledge, G.A., Phung, K.H., Mueller, L.D., Greer, L.F. -- Development and aging : two opposite but complementary phenomena / Feltes, B.C., De Faria Poloni, J., Bonatto, D. -- Aging as a process of deficit accumulation : its utility and origin / Mitnitski, A., Rockwood, K. -- Low-grade systemic inflammation connects aging, metabolic syndrome and cardiovascular disease / Guarner, V., Rubio-Ruiz, M.E. -- Modulating mTOR in aging and health / Johnson, S.C., Sangesland, M., Kaeberlein, M., Rabinovitch, P. -- Melatonin and circadian oscillators in aging : a dynamic approach to the multiply connected players / Hardeland, R. -- Diet-microbiota-health interactions in older subjects : implications for healthy aging / Lynch, D.B., Jeffery, I.B., Cusack, S., O'Connor, E.M., O'Toole, P.W. -- Systems biology approaches in aging research / Chauhan, A., Liebal, U.W., Vera, J., Baltrusch, S., Junghanss, C., Tiedge, M., Fuellen, G., Wolkenhauer, O., Köhling, R. -- Conservative growth hormone/IGF-1 and mTOR signaling pathways as a target for aging and cancer prevention : do we really have an antiaging drug? / Anisimov, V.N.
  • 2014From: Springer
    Bodh I. Jugdutt, editor.
    This book synthesizes the major research advances in molecular, biochemical, and translational aspects of aging and heart failure over the last four decades and addresses future directions in management and drug discovery. It presents clinical issues and molecular mechanisms related to heart failure, including the changing demographics in the aging population with heart failure; hypertension and prevention of diastolic heart failure in the aging population; polypharmacy and adverse drug reactions in the aging population with heart failure; changes in the heart that accompany advancing age from humans to molecules; aging-associated alterations in myocardial inflammation and fibrosis; and aging-related changes in mitochondrial function and implications for heart failure therapy. The book succinctly summarizes the large volume of data on these key topics and highlights novel pathways that need to be explored. Featuring contributions from leading clinician-scientists, Aging and Heart Failure: Mechanisms and Management is an authoritative resource on the major clinical issues in heart failure therapy in the elderly for cardiologists, gerontologists, and internists.
  • 2012From: Springer
    Margaret Pisani, editor.
  • 2014From: Springer
    Ronan M. Factora, editor.
    Increasingly, we hear of more and more elders falling victim to financial exploitation. Although this form of elder abuse has been recognized for years, its incidence, prevalence, and impact on the common individual has been only more recently brought to the spotlight. Despite these circumstances, recognition of risk factors and indicators of financial exploitation are not widely disseminated. Additionally, once situations are identified and confronted, the knowledge of what to do next is lacking. These gaps are present within the medical community, law-enforcement, and the finance community ? areas where opportunities for recognition and intervention are common. Our elders often have no idea of what to do when they see their own risk or when they fall victim. Aging and Money: Reducing Risk of Financial Exploitation and Protecting Financial Resources helps clinicians to integrate identification of such indicators of abuse into their geriatric assessment as well as guide them in performing an assessment of an individuals? financial decision-making capacity when appropriate. Aging and Money: Reducing Risk of Financial Exploitation and Protecting Financial Resources is an essential new text that provides the practicing clinician with information on identifying risk factors and clinical clues associated with financial exploitation and how to incorporate these steps into their practice.
  • 2008From: Springer
    José Marín-García ; with the collaboration of Michael J. Goldenthal, Gordon W. Moe.
    Post-genomic view of aging: definition, theories and observations -- Overview of cardiovascular aging -- Molecular and cellular methodologies: a primer -- Molecular and cellular phenotypes of cardiovascular aging -- Aging of the vasculature and related systems -- Aging and the cardiovascular-related systems -- Cardiomyopathy and heart failure in aging -- Atherosclerosis, hypertension and aging -- Metabolic syndrome, diabetes and cardiometabolic risks in aging -- Gender and cardiovascular diseases in aging -- Cardiac dysrhythmias and channelopathies in aging -- Genetics of life span: lessons from model organisms -- Profiling the aging cardiovascular system: transcriptional, proteomic, SNPs, gene mapping and epigenetics analysis -- Translational research: gene, pharmacogenomics and cell-based therapy in the aging heart -- Nutrition and exercise in cardiovascular aging: metabolic and pharmacological interventions -- Aging and the frontier ahead.
  • edited by Karen Eggleston and Shripad Tuljapurkar.
    PrintStatus: Not Checked OutLane Catalog Record
    Preface / Michael Armacost -- Introduction / Karen Eggleston and Shripad Tuljapurkar -- Population aging and economic growth / David E. Bloom -- How demography shapes individual, social, and economic transitions in Asia / Shripad Tuljapurkar -- Changing intergenerational transfers in aging Japan / Naohiro Ogawa, Amonthep Chawla and Rikiya Matsukura -- Gender, migration, and the well-being of the elderly in rural China / Shuzhuo Li ... [et al.] -- Marriage and the elderly in China / Maria Porter -- Financing health care in a rapidly aging Japan / Naoki Ikegami -- Population aging and the introduction of long-term care insurance in South Korea / Soonman Kwon -- Old-age pension reform in South Korea / Byongho Tchoe -- The diabetes epidemic in the Asia-Pacific / Karen Eggleston ... [et al.] -- Families dealing with dementia : insights from mainland China, Hong Kong, and Taiwan / Dolores Gallagher-Thompson ... [et al.] -- Elderly care in Singapore : the state as last resort / Meng-kin Lim.
  • 2010From: Springer
    [edited by] Sandra Gordon-Salant, Robert D. Frisina, Arthur N. Popper, Richard R. Fay
  • Martha Hostetter, Sarah Klein, and Douglas McCarthy.
    We examine the Program of All-Inclusive Care for the Elderly (PACE) model of care, focusing on On Lok Senior Health Services as the original program and exploring the potential for the model to be adapted and spread.
  • 2010From: Springer
    Ralph M. Trüeb, Desmond J. Tobin, editors.
    Gerontobiology of the Hair Follicle / Desmond J. Tobin -- Molecular Basis of Androgenetic Alopecia / Valerie Anne Randall -- Inflammatory Phenomena and Fibrosis in Androgenetic Alopecia / Ralph M. Trüeb -- Post-Menopausal Frontal Fibrosing Alopecia / Steven Kossard -- Female Pattern Hair Loss / M. Javed Mohungoo and Andrew G. Messenger -- Hair Growth Parameters in Pre- and Postmenopausal Women / Paradi Mirmirani, Fangyi Luo, Scott R. Youngquist, Brian K. Fisher and James Li, et al. -- Comparative Histopathology of Androgenetic Alopecia, Diffuse Alopecia, and Senescent Alopecia / David A. Whiting -- Comparative Gene Expression Profiling of Senescent and Androgenetic Alopecia Using Microarray Analysis / Paradi Mirmirani and Pratima Karnik -- The Aging Hair Pigmentary Unit / Desmond J. Tobin -- Oxidative Stress Associated Melanocyte-Loss and Hair Growth Capacity in the Aging Hair Follicle: A Model for Tissue-Specific Aging / Eva M. J. Peters -- Human Hair Follicle Melanocytes as a Proxy Cell Type in Neurodegeneration Research / Nikolaos Papageorgiou, Elisabeth Carpenter and Desmond J. Tobin -- Effect of UV Radiation on Scalp and Hair Growth / Claudine Piérard-Franchimont, Pascale Quatresooz and Gérald E. Piérard -- Hair Photoaging / Won-Soo Lee -- Effect of Tobacco Smoking on Hair / Ralph M. Trüeb -- Age-Related General Problems Affecting the Condition of Hair / Ralph M. Trüeb -- Aging of Scalp and Age-Related Disorders of Scalp / Desmond Gan and Rodney Sinclair -- Care of Aging Hair and Photoprotection / Zoe Diana Draelos -- Possibilities and Limitations for Reversal of Age-Related Hair Loss / Nina Otberg, Isabel Restrepo and Jerry Shapiro -- Possibilities and Limitations for Reversal of Age-Related Pigment Loss / Ralph M. Trüeb -- Evidence-Based Hair Transplantation / Andreas M. Finner -- Future Directions: Gene Polymorphism Diagnostics Relevant to Hair / Justine A. Ellis -- Future Directions : The Known and Unknown Roles of Hair-Follicle Stem Cell Types / Robert M. Hoffman -- Future Directions: Bioengineering the Hair Follicle / Kurt S. Stenn, Ying Zheng and Jen-Chih Hsieh -- Hair After Death / Andrew S. Wilson and Desmond J. Tobin.
  • prepared by Jacob Siegel.
  • 2008From: Springer
    edited by Juan F. Macías Núñez, J. Stewart Cameron, Dimitrios G. Oreopoulos.
  • 2012From: Springer
    edited by Michael Breitenbach, S. Michal Jazwinski, Peter Laun.
    Introduction -- Oxidative stresses and ageing -- The role of mitochondria in the aging processes of yeast -- The retrograde response and other pathways of interorganelle communication in yeast replicative aging -- Chronological aging in Saccharomyces cerevisiae -- Aging and the survival of quiescent and non-quiescent cells in yeast stationary-phase cultures -- Maximising the yeast chronological lifespan -- Amino acid homeostasis and chronological longevity in Saccharomyces cerevisiae -- DNA damage and DNA replication stress in yeast models of aging -- Yeast aging and apoptosis -- Cellular homeostasis in fungi: impact on the aging process -- Genome-wide analysis of yeast aging -- Genetic approaches to aging in budding and fission yeasts: new connections and new opportunities -- Evolution of asymmetric damage segregaton: a modelling approach -- Cellular ageing and the actin cyoskeleton.
  • by Wan He, Daniel Goodkind, and Paul Kowal.
    This report covers the demographic, health, and economic aspects of global population aging. After an examination of past and projected growth of the older population and dynamics of population aging, the report then covers health, mortality, and health care of the older population. Finally, work, pensions, and other economic characteristics of older people are addressed. Compared to previous versions of the report An Aging World, this edition is unique for expanding the analysis of aging trends to all countries and areas, with an emphasis on the differences among world regions. Where data are available, it also updates the latest statistics and trends for health and economic indicators.
  • 2015From: Springer Protocols
    Fulltext v. 2 (2015)From: Springer Protocols
    edited by Kan Wang, Center for Plant Transformation, Plant Sciences Institute, and Department of Agronomy, Iowa State University, Ames, IA, USA.
    Volume 1. Gateway®-compatible plant transformation vectors /Mark A. Smedley and Wendy A. Harwood -- Brachypodium distachyon /Jennifer N. Bragg ... [et al.] -- Medicago truncatula transformation using cotyledonary explants /Elane Wright and Zeng-Yu Wang -- Medicago truncatula transformation using leaf explants /Viviane Cosson, Alexis Eschstruth , and Pascal Ratet -- Setaria viridis /Joyce Van Eck and Kerry Swartwood -- Barley (Hordeum vulgare L.) transformation using immature embryos /Cornelia Marthe, Jochen Kumlehn, and Goetz Hensel -- Barley (Hordeum vulgare L.) transformation using embryogenic pollen cultures /Ingrid Otto, Andrea Müller, and Jochen Kumlehn -- Maize (Zea mays L.) /Bronwyn Frame ... [et al.] -- Maize, tropical (Zea mays L.) /Shireen K. Assem -- Finger millet [Eleusine coracana (L.) Gaertn.] /Stanislaus Antony Ceasar and Savarimuthu Ignacimuthu -- Oat (Avena sativa L.) /Sebastian Gasparis and Anna Nadolska-Orczyk -- Rice, indica (Oryza sativa L.) /Yukoh Hiei, Yuji Ishida, and Toshihiko Komari -- Rice, japonica (Oryza sativa L.) /Marcy Main, Bronwyn Frame, and Kan Wang -- Sorghum (sorghum bicolor ) /Xiaomei Guo, Zhengxiang Ge, Shirley J. Sato, and Tom E. Clemente -- Wheat (Triticum aestivum L.) transformation using immature embryos /Yuji Ishida ... [et al.] -- Wheat (Triticum aestivum L.) transformation using mature embryos /Eva Medvecká and Wendy A. Harwood -- Alfalfa (Medicago sativa L.) /Chunxiang Fu ... [et al.] -- Clovers (Trifolium spp.) /Samira Rahimi-Ashtiani ... [et al.] -- Clover, red (Trifolium pratense) /Michael L. Sullivan and Kenneth H. Quesenberry -- Cowpea [Vigna unguiculata (L.) walp.] /Ratikanta Behura ... [et al.] -- Lentil (Lens culinaris medik) /Ufuk Celikkol Akcay, Meral Yücel, and Hüseyin Avni Öktem -- Soybean [Glycine max (L.) Merr.] /Diane Luth, Katey Warnberg, and Kan Wang -- Brassica oleracea and B. napus /Penny A. C. Hundleby née Sparrow and Judith A. Irwin -- Cucumber (Cucumis sativus L.) and kabocha squash (Cucurbita moschata Duch) /Yoshihiko Nanasato and Yutaka Tabei -- Pepper, chili (Capsicum annuum) /Jung Min ... [et al.] -- Pepper, sweet (Capsicum annuum) /Iris Heidmann and Kim Boutilier -- Sugar beet (Beta vulgaris L.) /Hiroyo Kagami ... [et al.] -- Tomato (Solanum lycopersicum) /Dora Garcia, Javier Narváez-Vásquez, and Martha L. Orozco-Cárdenas.
  • 2007From: Ovid
    [edited by] Joseph Alpert, Ian Nixon ; associate editors, Gerard P. Aurigemma ... [et al.].
  • 2011From: Ovid
    Aurigemma, Gerard P.; Nixon, J. V.
  • 2010From: Springer
    [edited by] Laurent Zelek, Nicole Zernik.
  • 2007From: Springer
    edited by C. Meyers.
    Also available: Print – 2007
  • Victoria A. Harden.
    PrintStatus: Not Checked OutLane Catalog Record
    Society was not prepared in 1981 for the appearance of a new infectious disease, but we have since learned that emerging and reemerging diseases will continue to challenge humanity. This work is the first history of HIV/AIDS written for a general audience that emphasizes the medical response to the epidemic. The author, a medical historian approaches the AIDS virus from philosophical and intellectual perspectives in the history of medical science, discussing the process of scientific discovery, scientific evidence, and how laboratories found the cause of AIDS and developed therapeutic interventions. Furthermore, her book places AIDS as the first infectious disease to be recognized simultaneously worldwide as a single phenomenon. After years of believing that vaccines and antibiotics would keep deadly epidemics away, researchers, doctors, patients, and the public were forced to abandon the arrogant assumption that they had conquered infectious diseases. By presenting a discussion of the history of HIV/AIDS and analyzing how aspects of society advanced or hindered the response to the disease, the book illustrates how medicine identifies and evaluates new infectious diseases quickly and what political and cultural factors limit the medical community's response.
  • 2015From: ProQuest Ebook Central
    Peter Piot ; translated by Laurence Garey.
    Peter Piot, founding executive director of the Joint United Nations Programme on HIV/AIDS (UNAIDS), recounts his experience as a clinician, scientist, and activist fighting the disease from its earliest manifestation to today. The AIDS pandemic was not only catastrophic to the health of millions worldwide but also fractured international relations, global access to new technologies, and public health policies in nations across the globe. As he struggled to get ahead of the disease, Piot found science does little good when it operates independently of politics and economics, and politics is worthless if it rejects scientific evidence and respect for human rights. Piot describes how the epidemic altered global attitudes toward sexuality, the character of the doctor-patient relationship, the influence of civil society in international relations, and traditional partisan divides. AIDS thrust health into national and international politics where, he argues, it rightly belongs. The global reaction to AIDS over the past decade is the positive result of this partnership, showing what can be achieved when science, politics, and policy converge on the ground. Yet it remains a fragile achievement, and Piot warns against complacency and the consequences of reduced investments. He refuses to accept a world in which high levels of HIV infection are the norm. Instead, he explains how to continue to reduce the incidence of the disease to minute levels through both prevention and treatment, until a vaccine is discovered. -- Publisher description.
  • 2012From: ProQuest Ebook Central
    Nicoli Nattrass.
    The conspiratorial move against HIV science and its consequences -- AIDS origin conspiracy theories in the United States and South Africa -- Who believes AIDS conspiracy theories and why leadership matters -- Science, politics, and credibility : David Gilbert fights AIDS conspiracy beliefs in US prisons -- Science, conspiracy theory, and the South African AIDS policy tragedy -- Hero scientists, cultropreneurs, living icons, and praise-singers : AIDS denialism as community -- Defending the imprimatur of science : Duesberg and the medical hypotheses saga -- The conspiratorial move and the struggle for evidence-based medicine.
  • Perry N. Halkitis.
    30 years and counting -- The men of the AIDS generation -- Enter HIV -- Surviving AIDS -- And then middle age -- Resilience.
  • 2008From: ClinicalKey
    [edited by] Raphael Dolin, Henry Masur, Michael S. Saag.
    AIDS treatments continues to evolve. Now, so does the definitive reference on this complex and challenging subject. "AIDS Therapy, 3rd Edition" not only brings you comprehensive guidance on the latest treatments for HIV/AIDS and the full range of related disorders and syndromes, but also comes with access to updates online--so you can always tap into the most current therapy guidelines. Written by a "who's who" of leading global experts, the new edition of this classic reference is a must for any clinician who manages patients with HIV/AIDS. The most comprehensive coverage available on AIDS treatment equips you to meet any clinical challenge. Contributions from a large cast of noted international authorities put global "best practices" at your fingertips. Advice from some of the most respected experts in the field helps you manage your patients confidently.
  • M.J. Harrison, T.E.J. Healy, J.A. Thornton.
    PrintStatus: Not Checked OutLane Catalog Record
    pt. 1. The Basic sciences -- pt. 2. Clinical practice.
  • v. 1-3, 1881-82.From: Google Books
    Fulltext (v.2 1881)From: Google Books
    Fulltext (v.3 1882)From: Google Books
    Fothergill, J. Milner; Thorowgood, John C.
    pt. 1. Semeiology, specially designed for students preparing for examinations (1883 : 75 p.) -- pt. 2. Physical (1881 : [2], 61 p.) / J.C. Thorowgood -- pt. 3. What to ask (1882 : 66 p.).
  • 2010From: CRCnetBASE
    edited by Bhola R. Gurjar, Luisa T. Molina, Chandra S.P. Ojha ; foreword by Mario J. Molina.
  • 2013From: IARC
    edited by Kurt Straif, Aaron Cohen, and Jonathan Samet.
    Introduction -- Geographical distribution of air pollutants -- Characterizing exposures to atmospheric carcinogens -- Combustion emissions -- Sources of air pollution: gasoline and diesel engines -- Household use of biomass fuels -- Polycyclic aromatic hydrocarbons in ambient air and cancer -- Hazardous air pollutants: approaches and challenges in identigying assessment priorities -- Household air pollution -- Using experimental data to evaluate the carcinogenicity of mixtures in air pollution -- Mechanistic considerations for air pollution and lung cancer: genotoxicity and molecular biomarker data from experimental and human studies -- Biomarkers of air pollution: DNA and protein adducts -- Combined effect of air pollution with other agents.
  • 2016From: Wellcome Trust
    edited by EM Jones, C Overy and EM Tansey.
  • Ruoting Jiang.
    Exposure to secondhand smoke (SHS) has been associated with a number of health outcomes including cardiovascular diseases, pulmonary malfunction, lung cancer, and mortality. To protect public health, over 100 countries have adopted comprehensive or partial legislations against smoking. In the United States, California was the first state to enact a statewide ban on smoking in indoor workplaces in 1994. However, due to the sovereign nation status of California Indian tribes, smoking is still allowed and exposure to SHS continues in nearly all California Indian casinos. Fine particulate matter (PM2.5) is a major component of SHS pollution, and has been implicated as a risk factor for a range of chronic and acute diseases. The EPA's reference method for quantifying PM2.5 mass concentrations uses filter-based gravimetric samplers, which must be operated for many hours to collect enough sample. Since the gravimetric approach cannot measure short-term variations in PM2.5 levels, many personal exposure and environmental monitoring studies have employed real-time monitors for measuring PM2.5 concentrations. However, real-time monitors require proper calibration to accurately represent particle mass concentrations. This study characterized PM2.5 concentrations with real-time SidePak particle monitors in a large sample of California Indian casinos, spanning all sizes and distributed widely across the state. By comparing the SidePak measurements with the standard gravimetric method, we first calibrated the SidePak monitors for different types of aerosols commonly encountered indoors and outdoors, including SHS. We then modeled the response of SidePak monitors to SHS for a range of relative humidity levels. Finally, we designed a systematic casino monitoring protocol, using the calibrated real-time monitors, to examine PM2.5 concentrations in a field survey of 36 California Indian casinos and 8 Reno casinos.
  • 2013From: WHO
    IOMC, Inter-Organization Programme for the Sound Management of Chemicals.
    Also available: Print – 2013
  • 2009From: CRCnetBASE
    editors, Giacomo Zaccone ... [et al.].
  • 2014From: Springer
    Zahid Hussain Khan, editor.
    1. Physiology of the Airway / Yoo Kuen Chan -- 2. Airway Assessment: A Critical Appraisal / Zahid H. Khan -- 3. Videolaryngoscopy and Indirect Intubating Aids in Airway Management / Sze-Ying Thong and Wendy H. L. Teoh -- 4. Perioperative Care of Ambulatory Anaesthesia / Anil Agarwal and Kamal Kishore -- 5. The Paediatric Airway: Normal and Abnormal / Ina Ismiarti Shariffuddin and Lucy Chan -- 6. Intubation of the Pediatric Patient / Josef Holzki -- 7. The Difficult Pediatric Airway: Management Options / Mahesh Vakamudi -- 8. Perioperative Management of Obstructive Sleep Apnea / Karen Mak and Edwin Seet -- 9. Airway Management in Traumatic Brain Injury (TBI) / Fauzia Anis Khan -- 10. Airway Management in Cervical Spine Injured Patients / Srikanth Sridhar and Carin A. Hagberg -- 11. Indigenous Devices in Difficult Airway Management / Virendra K. Arya -- 12. Cricothyrotomy / Virendra K. Arya -- 13. Surgical Airway / Jinbin Zhang and Orlando Hung -- 14. Surgical Approaches to Airway Management / Surender K. Malhotra -- 15. Difficult Airway in Obstetrics / Sunanda Gupta and Apoorva Gupta -- 16. Ultrasonography: Heralding a New Era in Airway Management / Michael Seltz Kristensen and Wendy H. L. Teoh.
  • 2012From: Springer
    edited by Carolyn C. Compton ... [et al.].
  • 2010Limited to 7 simultaneous usersFrom: STAT!Ref
    American Joint Committee on Cancer ; [editors, Stephen B. Edge ... et al.].
    General information on cancer staging and end-results reporting -- Head and neck -- Digestive system -- Thorax -- Musculoskeletal sites -- Skin -- Breast -- Gynecologic sites -- Genitourinary sites -- Ophthalmic sites -- Central nervous system -- Lymphoid neoplasms -- Personnel and contributors.
  • 2011From: Thieme eNeurosurgery
    [edited by] Franco DeMonte, Michael W. McDermott, Ossama Al-Mefty.
    "This new edition of Meningiomas proves a valuable contribution to the literature on the fascinating aspects of meningioma biology, diagnosis, and management"--Provided by publisher.
  • 2008From: ClinicalKey
    [edited by] Daniel M. Albert, Joan W. Miller ... [et al.].
    Genetics -- Immunology -- Microbiology -- Pharmacology and toxicology -- Principles of epidemiology -- Cornea and conjunctiva -- Refractive surgery -- Uveitis -- Lens -- Retina and vitreous -- Glaucoma -- Oculoplastics -- Ophthalmic pathology -- Neuro-ophthalmology -- Pediatric ophthalmology -- The eye and systemic disease -- Ocular oncology -- Trauma -- Optics -- Low vision -- Ethics and professionalism.
    Also available: Print – v. 1-4, 2008.
  • 2008From: Springer Protocols
    Laura E. Nagy, editor.
    Acute models of ethanol exposure to mice / Timothy P. Plackett and Elizabeth J. Kovacs -- A voluntary oral-feeding rat model for pathological alcoholic liver injury / George L. Tipoe ... [et al.] -- Intragastric ethanol infusion model in rodents / Hide Tsukamoto, Hasmik Mkrtchyan, and Alla Dynnyk -- A practical method of chronic ethanol administration in mice / Ruth A. Coleman ... [et al.] -- Analysis of ethanol developmental toxicity in zebrafish / Robert L. Tanguay and Mark J. Reimers -- The avian embryo in fetal alcohol research / Susan M. Smith -- Artificial rearing / Hector D. Dominguez and Jennifer D. Thomas -- Intragastric intubation of alcohol during the perinatal period / Sandra J. Kelly and Charles R. Lawrence -- Human monocytes, macrophages, and dendritic cells : alcohol treatment methods / Gyongyi Szabo and Pranoti Mandrekar -- Generation and use of primary rat cultures for studies of the effects of ethanol / Amanda Lindke, Barbara Tremper-Wells, and Michael W. Miller -- Development and properties of HepG2 cells that constitutively express CYP2E1 / Defeng Wu and Arthur I. Cederbaum -- Modeling the impact of alcohol on cortical development in a dish : strategies from mapping neural stem cell fate / Rajesh C. Miranda ... [et al.] -- Acetaldehyde-induced barrier disruption and paracellular permeability in Caco-2 cell monolayer / R.K. Rao -- Alcohol-induced oxidative stress in the liver : in vivo measurements / Gavin E. Arteel -- Isolation of Kupffer cells from rats fed chronic ethanol / Megan R. McMullen, Michele T. Pritchard, and Laura E. Nagy -- Dendritic cells in chronic in vivo ethanol exposure models / Kevin L. Legge and Annette J. Schlueter -- Formation and immunological properties of aldehyde-derived protein adducts following alcohol consumption / Geoffrey M. Thiele, Lynell W. Klassen, and Dean J. Tuma -- Assessment of natural killer (NK) and NKT cells in murine spleens and livers / Michael R. Shey and Zuhair K. Ballas -- Polyclonal and antigen-specific responses of T cells and T cell subsets / Betty M. Young ... [et al.] -- B-cell studies in chronic ethanol mice / Shilpi Verma ... [et al.] -- Histological analysis of bone / Urszula T. Iwaniec, Thomas J. Wronski, and Russell T. Turner -- Assessing effects of alcohol consumption on protein synthesis in striated muscles / Thomas C. Vary and Charles H. Lang -- Methods to investigate the effects of chronic ethanol on adipocytes / Becky M. Sebastian ... [et al.] -- Proteomic approaches to identify and characterize alterations to the mitochondrial proteome in alcoholic liver disease / Shannon M. Bailey ... [et al.] -- Alcoholic liver disease and the mitochondrial ribosome : methods of analysis / Alan Cahill and Peter Sykora -- Microarray analysis of ethanol-induced changes in gene expression / Robnet T. Kerns and Michael F. Miles.
  • 2011From: Springer
    Samir Zakhari, Vasilis Vasiliou, Q. Max Guo, editors.
    The World Health Organization has identified chronic alcohol consumption as one of the top ten risk factors for worldwide burden of disease. The International Agency for Research on Cancer has identified alcohol as carcinogenic to humans, including cancers of the upper aerodigestive tract, colon, liver and breast. Alcohol{u2019}s actions may be direct e.g. effects on retinoic acid and one-carbon metabolism, or indirect, through metabolites such as acetaldehyde and reactive oxygen species or through various signaling pathways that influence cell cycle and apoptosis that may contribute to carcinogenesis. This volume reviews the state of the art in alcohol-related cancer research in ten chapters.
  • Judith Norback.
    PrintStatus: Not Checked OutLane Catalog Record
  • 2012From: Wiley
    Iosief Abraha, Cristina Cusi.
    Part 1. Alcohol. Psychosocial interventions -- Effectiveness of brief alcohol interventions in primary care populations -- Brief interventions for heavy alcohol users admitted to general hospital wards -- Alcoholics Anonymous and other 12-step programmes for alcohol dependence -- Mentoring adolescents to prevent substance use disorders -- Universal school-based prevention programmes for alcohol misuse in young people -- Universal multicomponent prevention programmes for alcohol misuse in young people -- Universal family-based prevention programmes for alcohol misuse in young people -- Social norms interventions to reduce alcohol misuse in university or college students -- Psychosocial interventions for women enrolled in alcohol treatment during pregnancy -- Pharmacological interventions -- Benzodiazepines for alcohol withdrawal -- Anticonvulsants for alcohol withdrawal -- Acamprosate for alcohol dependence -- Baclofen for alcohol withdrawal -- Gamma-hydroxybutyrate for treatment of alcohol withdrawal and prevention of relapse -- Psychotropic analgesic nitrous oxide for alcohol withdrawal -- Efficacy and safety of pharmacological interventions for the treatment of alcohol withdrawal -- Opioid antagonists for alcohol dependence -- Pharmacologic interventions for pregnant women enrolled in alcohol treatment. Part 2. Drugs. Psychosocial interventions -- School-based prevention for illicit substance use disorders -- Interventions for prevention of substance use disorders by young people delivered in non-school settings -- Case management for persons with substance use disorders -- Motivational interviewing for substance use disorders -- Therapeutic communities for substance use disorders -- Interventions for drug-using offenders in the courts, secure estabishments and the community -- Psychosocial interventions for pregnant women in outpatient illicit drug treatment programmes compared to other interventions -- Cocaine dependence -- Psychosocial interventions for cocaine and psychostimulant amphetamine related disorders -- Antidepressants for cocaine dependence -- Antipsychotic medications for cocaine dependence -- Anticonvulsants for cocaine dependence -- Dopamine agonists for cocaine dependence -- Disulfiram for the treatment of cocaine dependence -- Efficacy of psychostimulant drugs for cocaine dependence -- Auricular acupuncture for cocaine dependence -- Psychosocial treatment for opiate dependence -- Psychosocial and pharmacological treatments versus pharmacological treatments for opioid detoxification -- Psychosocial combined with agonist maintenance treatments versus agonist maintenance treatments alone for treatment of opioid dependence -- Alpha2-adrenergic agonists for the management of opioid withdrawal -- Buprenorphine for the management of opioid withdrawal -- Psychosocial treatment for opiate dependence -- Psychosocial and pharmacological treatments versus pharmacological treatments for opioid detoxification -- Psychosocial combined with agonist maintenance treatments versus agonist maintenance treatments alone for treatment of opioid dependence -- Alpha2-adrenergic agonists for the management of opioid withdrawal -- Buprenorphine for the management of opioid withdrawal -- Buprenorphine maintenance versus placebo or methadone maintenance for opioid dependence -- Methadone at tapered doses for the management of opioid withdrawal -- Methadone maintenance at different dosages for opioid dependence -- Methadone maintenance therapy versus no opioid replacement therapy for opioid dependence -- Opioid antagonists under heavy sedation or anaesthesia for opioid withdrawal -- Opioid antagonists with minimal sedation for opioid withdrawal -- Oral naltrexone maintenance treatment for opioid dependence -- Sustained-release naltrexone for opioid dependence -- Heroin maintenance for chronic heroin-dependent individuals -- LAAM maintainance verus methadone maintenance for heroin dependence -- Detoxification treatments for opiate-dependent adolescents -- Maintenance treatments for opiate-dependent adolescents -- Maintenance agonist treatment for opiate-dependent adolescents -- Maintenance agonist treatments for opiate-dependent pregnant women -- Pharmacological treatments for depression during opoid dependence -- Inpatient versus other setttings for detoxification for opiod dependence -- Psychotherapeutic interventions for cannabis use or dependence in outpatient settings -- Pharmacological interventions for benzodiazepine mono-dependence management in outpatient settings -- Treatment for amphetamine dependence -- Treatment for amphetamine withdrawal -- Treatment for amphetamine psychosis -- Treatment for methaqualone dependence in adults.
  • editors: Cheryl J. Cherpitel [and others].
    PrintStatus: Not Checked OutLane Catalog Record
  • 2015From: ScienceDirect
    Amitava Dasgupta.
  • 2000From: NIAAA
    AOD thesaurusFrom: NIAAA
  • 2014From: ScienceDirect
    volume editors, Edith V. Sullivan and Adolf Pfefferbaum.
    "Alcohol is the most widely used drug in the world, yet alcoholism remains a serious addiction affecting nearly 20 million Americans. Our current understanding of alcohol's effect on brain structure and related functional damage is being revolutionized by genetic research, basic neuroscience, brain imaging science, and systematic study of cognitive, sensory, and motor abilities. Volume 125 of the Handbook of Clinical Neurology is a comprehensive, in-depth treatise of studies on alcohol and the brain covering the basic understanding of alcohol's effect on the central nervous system, the diagnosis and treatment of alcoholism, and prospect for recovery. The chapters within will be of interest to clinical neurologists, neuropsychologists, and researchers in all facets and levels of the neuroscience of alcohol and alcoholism"--Publisher's description.
  • 2011From: Springer
    Otto-Michael Lesch, Henriette Walter, Christian Wetschka, Michie Hesselbrock, Victor Hesselbrock.
  • edited by Eilish Gilvarry and Paul McArdle.
    Policy : the principles of service organization and practice / Paul McArdle and Eilish Gilvarry -- Determinants of substance misuse / Paul McArdle -- Drug use in young people : short-term effects and long-term harms / Dan Lubman, Yvonne Bonomo and Murat Yücel -- Young people, substances and harm / Mandy Abbott, Fariah Khan and Eilish Gilvarry -- Trends in substance use and abuse in young people / Cecilia A. Essau and Peter Wennberg -- Substance use and psychiatric comorbidity in children and adolescents / Michael Farrell -- The effectiveness of universal youth substance abuse prevention programmes / David R. Foxcroft, Debby Allen and Lindsey Coombes -- Prevention of substance abuse : targeted approaches / Paul McArdle -- Treatment : course and outcome / Eilish Gilvarry and Giles Hayden -- Legal and ethical issues in the treatment of children and young people / Sarah Woolrich -- Principles of assessment for adolescents with substance use disorders / Oscar G. Bukstein and Theresa Lutka-Fedor -- Assessment instruments and outcome measurement / Oscar G. Bukstein and Theresa Lutka-Fedor -- Biological markers (drugs) / Kim Wolff -- Assessement and management in the emergency department and the paediatric unit / Joan Robson -- Brief alcohol interventions in young people : evidence and applicability / Malathi Natarajan and Eileen Kaner -- Psychological interventions for young people with substance misuse disorders / Gillian Tober -- Empirical and clinical foundations of family-based interventions for adolescent substance abuse / Howard A. Liddle, Cynthia L. Rowe and Gayle A. Dakof -- Pharmacological treatment of adolescent substance use disorder / E. Jane Marshall and K.A.H. Mirza -- The role of primary care in management of substance use/abuse / Clare Gerada -- Integrated treatment of substance use disorders and co-occurring psychiatric disorders in adolescents / Robert D. Davies and Paula D. Riggs.
  • 2013From: Springer
    Ronald Ross Watson, Victor R. Preedy, Sherma Zibadi, editors.
    Part I. Overview and General Nutrition During Alcohol Use -- 1. Alcohol and Nutrition: An Overview / Francisco Santolaria and Emilio González-Reimers -- 2. Genetics of Alcohol Metabolism / Vijay A. Ramchandani -- 3. Laboratory Models Available to Study Alcohol and Nutrition / Nympha B. D'Souza EL-Guindy -- 4. Ethanol-Induced Lipid Peroxidation and Apoptosis in Embryopathy / Robert R. Miller Jr. -- 5. Alcohol Use During Lactation: Effects on the Mother-Infant Dyad / Julie A. Mennella -- Part II. Nutrients and Foods as Modified by Alcohol -- 6. Moderate Alcohol Administration: Oxidative Stress and Nutritional Status / Lorenzo Leggio, Anna Ferrulli, and Giovanni Addolorato -- 7. Alcohol Use and Abuse: Effects on Body Weight and Body Composition / Stefan Gazdzinski and Timothy C. Durazzo -- 8. Alcohol: Nutrition and Health Inequalities / Adrian Bonner and Margherita Grotzkyj-Giorgi -- 9. The Effect of Diet on Protein Modification by Ethanol Metabolites / Simon Worrall -- 10. Vitamin B12 De fi ciency in Alcoholics / Alberto Fragasso -- 11. American Indians/Alaskan Natives and Alcohol: Biology, Nutrition, and Positive Programs / Felina M. Cordova, Michael H. Trujillo, and Roger Dale Walker -- Part III. Nutrient Effects on Alcohol Metabolism -- 12. Metabolism of Ethanol to Acetaldehyde in the Rat Mammary Tissue: Inhibitory Effects of Plant Polyphenols and Folic Acid / Gerardo Daniel Castro and José Albe -- 13. Dietary Zinc Supplementation and Prenatal Ethanol Exposure / Peter Coyle, Brooke Summers-Pearce, Carina J. Cowley, and Allan M. Rofe -- 14. Tocotrienol and Cognitive Dysfunction Induced by Alcohol / Kanwaljit Chopra and Vinod Tiwari -- 15. Soy Products Affecting Alcohol Absorption and Metabolism / Mitsuyoshi Kano and Norihiro Kubota -- 16. Oats Supplementation and Alcohol-Induced Oxidative Tissue Damage / Christopher B. Forsyth, Yueming Tang, Robin M. Voigt, Turan Rai, and Ali Keshavarzian -- 17. Fish Oil n-3 Fatty Acids to Prevent Hippocampus and Cognitive Dysfunction in Experimental Alcoholism / Nataliya A. Babenko -- 18. Alcohol in HIV and Possible Interactions with Antiretroviral Medications / Marianna K. Baum, Sabrina Sales-Martinez, and Adriana Campa -- Part IV. Alcohol Interactions with Foods -- 19. Popular Energy Drinks and Alcohol / Erin C. Duchan -- 20. The Psychological Synergistic Effects of Alcohol and Caffeine / Ambereen Ameer and Ronald Ross Watson -- 21. Alcohol and Smoking: A Correlation of Use in Youth? / Meghan Denning and Ronald Ross Watson -- 22. Are There Physiological Correlations Between Alcohol and Tobacco Use in Adults? / Cynthia Lee and Ronald Ross Watson -- 23. Alcohol, HIV/AIDS, and Liver Disease / Tamsin A. Knox, Logan Jerger, and Alice M. Tang -- Part V. Alcohol and Chronic Diseases -- 24. Nutritional Status, Socioeconomic Factors, Alcohol, and Cataracts / Vaishali Agte and Kirtan V. Tarwadi -- 25. Alcohol Intake and High Blood Pressure / Amy Z. Fan and Yueren Zhou -- 26. Alcohol and Dyslipidemia / Indrajit Chowdhury -- 27. Dietary Antioxidants in Chronic Alcoholic Pancreatitis / Mirosław Jarosz and Ewa Rychlik -- 28. Alcohol Consumption, Lifestyle Factors, and Type 2 Diabetes / Martin D. Stricker, Henk F.J. Hendriks, and Joline W.J. Beulens -- 29. Alcohol, Overweight and Obesity / Sasiwarang Goya Wannamet -- 30. Nutrition: Alcohol and Anorectic and Bulimic Adolescents / Konstantina Magklara -- 31. Viral Infections and Cancer During Alcohol Use / Malgorzata Schlegel-Zawadzka -- Part VI. Cancer as Modified and Induced by Alcohol -- 32. Ethanol and Hepatocarcinogenesis / Helmut K. Seitz and Felix Stickel -- 33. Alcohol, Diet, and Their Interaction in Colorectal and Urinary Tract Tumors / María Marta Andreatta , Aldo R. Eynard, and Alicia Navarro -- 34. Alcohol, Acetaldehyde, and Digestive Tract Cancer / Satu Väkeväinen and Mikko Salaspuro -- 35. Alcohol Intake and Esophageal Cancer: Epidemiologic Evidence / Jill Layton and Jianjun Zhang -- Part VII. Alcohol and Liver Diseases -- 36. A Nutritional Approach to Prevent Alcoholic Liver Disease / Samuel William French -- 37. Nutraceutical Potential of Indigenous Plant Foods and Herbs for Treatment of Alcohol-Related Liver Damage / Vaishali Agte and Upendra Raghunath Gumaste -- 38. Alcohol and Nutrition as Risk Factors for Chronic Liver Disease / Stefano Bellentani, Claudio Tiribelli, and Giorgio Bedogni -- 39. Alcohol-Related Liver Disease: Roles of Insulin Resistance, Lipotoxic Ceramide Accumulation, and Endoplasmic Reticulum Stress / Suzanne M. de la Monte -- 40. Nutrition and Alcoholic and Nonalcoholic Fatty Liver Disease: The Significance of Cholesterol / Munechika Enjoji , Kenichiro Yasutake, Motoyuki Kohjima, and Makoto Nakamuta -- 41. Dietary Fatty Acids and Alcoholic Liver Disease / Takayo Kawakami, Yasuko Murakami, and Misako Okita -- 42. Nutrition in Alcoholic Steatohepatitis / Juan Caballeria, Javier Michelena, and Jose Altamirano -- 43. Alcoholic and Nonalcoholic Fatty Liver Disease and Vitamin A / Gabriela Villaça Chaves and Wilza Arantes.
  • 2014From: Springer
    edited by David M. Guidot, Ashish J. Mehta.
    Alcohol Use Disorders and the Lung: A Clinical and Pathophysiological Approach is an excellent resource for clinicians who care for individuals affected by alcohol use disorders in diverse settings. Although alcohol abuse alone does not cause acute lung injury, it renders the lung susceptible to dysfunction in response to the inflammatory stresses of sepsis, trauma, and other clinical conditions recognized to cause acute lung injury. In parallel, these same pathophysiological effects of alcohol abuse significantly increase the risk of a wide range of serious lung infections. Many clinicians involved in the primary treatment of alcohol use disorders, such as addiction psychiatrists, will find this text of interest as it will expand their understanding of the health consequences of alcohol use disorders. In parallel, clinicians who specialize in pulmonary and/or critical care medicine will have a unique resource that provides a comprehensive review of the pathophysiology of alcohol-related lung disorders and insights into evolving therapeutic options in these vulnerable individuals. Alcohol Use Disorders and the Lung: A Clinical and Pathophysiological Approach fills a gap in the literature and presents the evolving clinical research that may soon lead to novel therapies that can improve lung health in individuals with alcohol use disorders and co-existing conditions such as HIV infection.
  • 2016From: Springer
    Naga Chalasani, Gyongyi Szabo, editors.
  • 1974-From: Google Books
    Senate Select Committee on Laws Relating to Alcoholic Beverages.
    v. 1. Final report -- v. 2. Alcohol abuse and alcoholism -- v. 4. Summary of Federal and state alcoholism programs.
    Also available: Print – v. 1, 1974.
  • 2009From: Springer
    Jérôme Hoessler.
  • 2014From: Springer
    Philip Rubin, Louis S. Constine, Lawrence B. Marks, editors.
    The literature on the late effects of cancer treatment is widely scattered in different journals since all major organ systems are affected and management is based on a variety of medical and surgical treatments. The aim of ALERT Adverse Late Effects of Cancer Treatment is to offer a coherent multidisciplinary approach to the care of cancer survivors. The central paradigm is that cytotoxic multimodal therapy results in a perpetual cascade of events that affects each major organ system differently and is expressed continually over time. Essentially, radiation and chemotherapy are intense biologic modifiers that allow for cancer cure and cancer survivorship but accelerate senescence of normal tissues and increase the incidence of age-related diseases and second malignant tumors. Volume 1 of this two-volume work focuses on the general concepts and principles relevant to late effects and on the dynamic interplay of molecular, cytologic and histopathologic events that lead to altered physiologic and metabolic functions and their clinical manifestations. Chapters are also included on legal issues, economic aspects, nursing, psychological issues and quality of life.
  • 2014From: Springer
    Philip Rubin, Louis S. Constine, Lawrence B. Marks, editors.
    The literature on the late effects of cancer treatment is widely scattered in different journals since all major organ systems are affected and management is based on a variety of medical and surgical treatments. The aim of ALERT Adverse Late Effects of Cancer Treatment is to offer a coherent multidisciplinary approach to the care of cancer survivors. The central paradigm is that cytotoxic multimodal therapy results in a perpetual cascade of events that affects each major organ system differently and is expressed continually over time. Essentially, radiation and chemotherapy are intense biologic modifiers that allow for cancer cure and cancer survivorship but accelerate senescence of normal tissues and increase the incidence of age-related diseases and second malignant tumors. Volume 2 of this two-volume work comprehensively documents potential late effects in all the normal tissue anatomic sites in the human body. The detection, diagnosis, management and prevention of effects are all considered in detail, and prognostic outcomes are discussed. Radiation risk factors and interactions with chemotherapy effects are clearly presented. The text is accompanied by numerous supportive illustrations and tables.
  • 2014From: Springer
    Alexander Leff, Randi Starrfelt.
    This book is a comprehensive review of the main acquired disorders of reading: hemianopic, pure and central alexia. The authors review the diagnostic criteria for each of the different types of disorder, and the efficacy of the therapeutic studies that have attempted to remediate them. The different theoretical models of adult reading, which largely rest on how the reading system responds to injury, are also discussed and evaluated. Focal brain injury caused by stroke and brain tumors are discussed in depth as are the effects of dementia on reading. This book starts with a chapter on normal reading, followed by chapters on hemianopic alexia, pure alexia and central alexia, each structured in the same way, with: a description of the condition; a historical review of cases to date; psychophysics; consideration of the causative lesions; evidence from functional imaging studies on patients and, most importantly, a review of the evidence base for treating each condition. Finally, there is a chapter on how patient data has informed how we think about reading.
  • 2007From: Springer
    edited by J. Seckbach.
  • 2009From: Springer
    Bernd H. A. Rehm, editor.
  • Raymond Albert Ryckman.
    In this work we present a series of scientific contributions made to the study of the impact of projectiles into tissue-like materials, specifically the synthetic artificial tissue simulant Perma-Gel. These contributions consist of a combination of experimental observations, algorithmic ideas and numerical tools which demonstrate a series of problems and solutions to trying to simulate nearly incompressible soft tissues using finite elements. A number of experiments were performed by taking high-speed footage of the firing of spherical steel bullets at different speeds into Perma-Gel, a new thermoplastic material used as a proxy to human muscle tissue. This work appears to be the first publicly released experimental work using Perma-Gel and is part of the small amount of non-classified work looking at ballistic gelatin behavior. A number of experimental observations were made regarding the material behavior, elastic and plastic deformation around the projectile, and the possibility of cavitation. This work introduces an explicit dynamic contact algorithm that takes advantage of the asynchronous time stepping nature of Asynchronous Variational Integrators (AVI) to improve performance when simulating elastic-body rigid-wall contact. We demonstrate a number of desirable properties over traditional one-time-step methods for the simulation of solid dynamics and provide a number of examples highlighting the advantages of this method. The explicit contact algorithm and AVI was used to simulate the impact of a projectile into a simulated block of gelatin, but was hindered by difficulties using the realistic material parameters. Using a parallelized version of the algorithm, large-scale simulations were performed for progressively smaller shear moduli. As the simulations approached realistic values for the shear modulus, unstable element configurations formed which required infeasibly small time steps to successfully resolve. The behavior observed for the shear moduli we could numerically simulate with did not resemble the experimental results. To simulate with smaller values, we had to go to an axisymmetric setting. The axisymmetric setting increased the range of shear moduli which could be simulated and demonstrated the same dynamic behavior, though the issue of unstable element configurations continued to occur in extreme cases. To deal with the issue of unstable elements, we created an axisymmetric remeshing strategy to compensate for the unstable element configurations and insufficient spatial resolution. This strategy consists of periodically applying a remeshing and transfer algorithm that updates highly deformed finite element meshes with configurations formed with elements having uniform aspect ratios and local refinement in important areas. The axisymmetric setting with remeshing increased the range of potential shear modulus values that could be simulated. This allowed for the identification of qualitative similarities in the transient behavior between the numerical results and the experimental footage.
  • Eugene Davydov.
    Availability of massive amounts of genomic data from hundreds of species has introduced many challenging computational problems as well as the need for efficient algorithmic tools that leverage multiple species information to facilitate biological analysis. This dissertation discusses two such problems: noncoding RNA multiple structural alignment and constrained element detection. Noncoding RNA genes (ncRNAs) are regions of the genome that are transcribed but not translated into protein, and fold directly into secondary and tertiary structures which can have a variety of important biological functions. Because their function depends closely on the secondary structure, ncRNAs often do not exhibit enough primary sequence conservation to be properly aligned using standard sequence-based methods. I therefore consider the problem of RNA multiple structural alignment, i.e., performing sequence alignment and secondary structure prediction simultaneously. In the first part of this dissertation I introduce a novel graph theoretic framework for analyzing this problem and prove that when the number of sequences is not fixed it is NP-complete. I also provide a polynomial time algorithm that approximates the optimal solution to within a factor of O(log^2 n). Constrained elements are regions of the human genome exhibiting evidence of purifying selection and therefore biological function. Computational identification of such elements is one of the major goals of comparative genomics. In the second part of this dissertation I present GERP++, a new tool for efficient constrained element detection that significantly improves on one of the current leading methods, GERP. While retaining GERP's biological transparency and metric for quantifying position-specific constraint, GERP++ uses a more rigorous method for computing evolutionary rates and a novel algorithm for element identification that uses statistical significance directly to evaluate and rank candidate elements. These algorithmic improvements decrease the running time by several orders of magnitude in practice, enabling high-throughput analysis of large data sets. Furthermore, I present analysis and biological interpretation of constrained elements identified by GERP++ in the human genome from recently available multiple species alignments.
  • George T. Heineman, Gary Pollice, and Stanley Selkow.
  • Berkant Savas.
  • 2007From: Springer
    A. Yokota, T. Fujii, K. Goto (eds.).
  • written by Liz Richardson.
    Recent initiatives have sought to close gaps between the two federal agencies' medical technology evaluation processes.
  • Fernando Amat Gil.
    Cryo-Electron tomography (CET) is the only imaging technology capable of visualizing the 3D organization of intact bacterial whole cells at nanometer resolution in situ. However, quantitative image analysis of CET datasets is extremely challenging due to very low signal to noise ratio (well below 0dB), missing data and heterogeneity of biological structures. In this thesis, we present a probabilistic framework to align CET images in order to improve resolution and create structural models of different biological structures. The alignment problem of 2D and 3D CET images is cast as a Markov Random Field (MRF), where each node in the graph represents a landmark in the image. We connect pairs of nodes based on local spatial correlations and we find the "best'' correspondence between the two graphs. In this correspondence problem, the "best'' solution maximizes the probability score in the MRF. This probability is the product of singleton potentials that measure image similarity between nodes and the pairwise potentials that measure deformations between edges. Well-known approximate inference algorithms such as Loopy Belief Propagation (LBP) are used to obtain the "best'' solution. We present results in two specific applications: automatic alignment of tilt series using fiducial markers and subtomogram alignment. In the first case we present RAPTOR, which is being used in several labs to enable real high-throughput tomography. In the second case our approach is able to reach the contrast transfer function limit in low SNR samples from whole cells as well as revealing atomic resolution details invisible to the naked eye through nanogold labeling.
  • 2016From: NLM
  • 1904-From: Google Books
    von Dr. Julius Schmidt ...
    Also available: Print – 1908-11.
  • 2015From: Springer
    Jozef Rovenský, Tibor Urbánek, Boldišová Olʹga, James A. Gallagher, editors.
    This book comprehensively describes alkaptonuria and ochronosis. Beginning with the history, genetics, pathophysiology and diagnostics of the disease, the authors subsequently present a detailed characterization of its clinical manifestation in the spine, peripheral joints, eyes, ears, visceral organs and respiratory tract, its pathological anatomy and histology, as well as differential diagnosis. This is complemented by the latest data on therapy and experimental models of alkaptonuria, and supported by several case reports. Numerous pictures and radiological images document the clinical symptoms, giving the reader a solid understanding of the disease. On the basis of the editor?s and authors? own extensive observations, the book offers an analysis of protein metabolism and aromatic amino acids in the context of alkaptonuria. Written by international experts in the field, the book offers a valuable reference guide for healthcare professionals working in rheumatology, dermatology, pulmonology, otolaryngology and histopathology.
  • uitgegeven, geïllustreerd en van aanteekeningen voorzien door een Commissie van Nederlandsche geleerden.
    PrintStatus: Not Checked OutLane Catalog Record
    v 1. 1673-1676 -- v. 2. 1676-1679 -- v. 3. 1679-1682 -- v. 4. 1683-1684 -- v. 5. 1685-1686 -- v. 6. 1686-1687 -- v. 7. 1687-1688 -- v. 8. 1688-1692 -- v. 9. 1692-1694 -- v. 10. 1694-1695 -- v. 11. 1695-1696 -- v. 12. 1696-1699 -- v. 13. 1700-1701 -- v. 14. 1701-1704 -- v. 15. 1704-1707.
  • 2009From: Springer
    Elena Aimar, Antonio Schindler, Irene Vernero.
  • 2015From: Springer
    edited by Mieczyslaw Pokorski.
    Respiratory allergy is constantly encountered and is sharply on the rise, particularly in the two most vulnerable age-groups: young children and seniors. Allergy results in airway hyperactivity and increased airway resistance, with all inflammatory sequelae being ensued. The chapters show how respiratory allergy research is interconnected with other disciplines by discussing neurotransmitter, membrane receptor, and ionic channel mechanisms of allergy and by giving diagnostic and pharmacological cues on desensitization and therapy.
    Also available: Print – 2015
  • 2007From: Springer
    edited by Phil Lieberman and John A. Anderson.
    Allergic disease: pathophysiology and immunopathology -- Approach to the allergic patient -- Diagnostic tests in allergy -- Environmental allergens -- Anaphylaxis -- Insect sting allergy -- The child with asthma -- Asthma in adults: diagnosis and management -- Allergic rhinitis: diagnosis and treatment -- Sinusitis and otitis media -- Diagnosis and treatment of ocular allergy -- Urticaria and angioedema -- Atopic dermatitis -- Contact dermatitis and other contact reactions -- Food allergy and intolerance -- Allergic and allergic-like reactions to drugs and other therapeutic agents -- Antihistamines -- β-adrenergic agonists -- Theophylline -- Antileukotriene agents in the management of asthma -- Cromolyn and nedocromil: nonsteroidal anti-inflammatory therapy for asthma and other allergic diseases -- Anticholinergic agents in respiratory diseases -- Glucocorticoid therapy in asthma -- Anti-IgE therapy -- Environmental control of respiratory indoor allergens -- Allergen immunotherapy -- Controversies in allergy and allergy-like diseases -- The patient with 'too many infections'.
  • editor-in-chief, A. Barry Kay ; editors, Allen P. Kaplan, Jean Bousquet, Patrick G. Holt ; foreword by K. Frank Austen.
    PrintStatus: Not Checked OutLane Catalog Record
  • 2016From: Springer
    Massoud Mahmoudi, editor.
    Chapter 1. Introduction to Immune System -- Chapter 2. The History and Physical Examination of the Allergic Patient -- Chapter 3. Prevalence of Allergic Diseases in Children, adults and Elderly -- Chapter 4. Allergic Diseases of the Eye -- Chapter 5. Prevalence of Pollens in the United States and Elsewhere -- Chapter 6. Allergic Rhinitis: Diagnosis and Treatment -- Chapter 7. The Effect of Rhinitis on Sleep, Quality of Life, Daytime Somnolence, and Fatigue -- Chapter 8. Sinusitis -- Chapter 9. Allergic Diseases of the Ear -- Chapter 10. Cough and Allergic Diseases -- Chapter 11. Urticaria and Angioedema -- Chapter 12. Atopic Dermatitis -- Chapter 13. Allergic Contact Dermatitis -- Chapter 14. Pediatric Asthma -- Chapter 15. Adult Asthma -- Chapter 16. Exercise-Induced Bronchoconstriction -- Chapter 17. Occupational Asthma -- Chapter 18. Asthma and Pregnancy -- Chapter 19. Asthma and Pseudo-asthma -- Chapter 20. Hypersensitivity Pneumonitis -- Chapter 21. All Allergic Bronchopulmonary Aspergillosis -- Chapter 22. Serum Sickness -- Chapter 23. Complement Systems and Allergy Diseases -- Chapter 24. Food Allergy -- Chapter 25. Insect Allergy -- Chapter 26. Latex Allergy -- Chapter 27. Drug Allergy -- Chapter 28. Smoke, Pollution, and Allergy -- Chapter 29. Sick Building Syndrome -- Chapter 30. Allergy in the Elderly -- Chapter 31. Diagnostic Testing in Allergic Diseases -- Chapter 32. Primary Immunodeficiencies -- Chapter 33. HIV Infection -- Chapter 34. Complementary and Alternative Medicine in treatment of Allergic and Asthmatic Disease -- Chapter 35. Nutrition, Diet and Allergic Diseases -- Chapter 36. Prevention and Control Measures in Management of Allergic Diseases -- Chapter 37. Antihistamines and Mast Cell Stabilizers -- Chapter 38. Bronchodilators -- Chapter 39. Glucocorticoids -- Chapter 40. Anti-Immunoglobulin E (IgE) Therapy -- Chapter 41. Allergy Immunotherapy -- Chapter 42. Anaphylaxis and Its Management. .
  • 2006From: Karger
    volume editor, Reto Crameri.
    Also available: Print – 2006
  • 2016From: Springer
    Mieczyslaw Pokorski, editor.
    Chapter 1. Spirometry or Body Plethysmography for the Assessment of Bronchial Hyperresponsiveness, R. Merget, F. Nensa, E. Heinze, D. Taeger, T. Bruening -- Chapter 2. Clinical Effects, Exhaled Breath Condensate pH and Exhaled Nitric Oxide in Humans after Ethyl Acrylate Exposure, F. Hoffmeyer, J. B?nger, C. Mons?, H. Berresheim, B. Jettkant, A. Beine, T. Br?ning, K. Sucker -- Chapter 3. Effectiveness of PCR and Immunofluorescence Techniques for Detecting Human Cytomegalovirus in Blood and Bronchoalveolar Lavage Fluid, A. Ro?y, K. Duk, B. Szumna, P. Jagu?, D. Gawryluk, J. Chorostowska-Wynimko -- Chapter 4. The Role of Ion Channels to Regulate Airway Ciliary Beat Frequency During Allergic Inflammation, M. Joskova, M. Sutovska, P. Durdik, D. Koniar, L. Hargas, P. Banovcin, M. Hrianka, V. Khazaei, L. Pappova, S. Franova -- Chapter 5. Content of Asthmagen Natural Rubber Latex Allergens in Commercial Disposable Gloves, C. Bittner, M. Velasco Garrido, L.H. Krach, V. Harth -- Chapter 6. Thermal Sensitivity and Dimethyl Sulfoxide (DMSO), K. Takeda, M. Pokorski, Y. Okada -- Chapter 7. IgE Reactivity, Work Related Allergic Symptoms, Asthma Severity, and Quality of Life in Bakers with Occupational Asthma, C. Bittner, M. Velasco Garrido, V. Harth, A.M. Preisser -- Chapter 8. Effects of Selective Inhibition of PDE4 by YM976 on Airway Reactivity and Cough in Ovalbumin-Sensitized Guinea Pigs, J. Mokry, A. Fulmekova, I. Medvedova, M. Kertys, P. Mikolka, P. Kosutov?, D. Mokr? -- Chapter 9. Airway Defense Control Mediated via Voltage-Gated Sodium Channels, M. Kocmalova, M. Joskova, S. Franova, P. Banovcin, M. Sutovska -- Chapter 10 -- Virological Characteristics of the 2014/2015 Influenza Season Based on Molecular Analysis of Biological Material Derived from I-MOVE, E. Hallmann-Szeli?ska, K. Bednarska, M. Korczy?ska, I. Paradowska-Stankiewicz, L.B. Brydak.
    Also available: Print – 2016
  • 2012From: Karger
    volume editor John Bienenstock.
    Relations between asthma and psychological distress: an old idea revisited -- Brain and asthma: what are the linkages? -- Stress-related programming of autonomic imbalance: role in allergy and asthma -- Role of parasympathetic nerves and muscarinic receptors in allergy and asthma -- Developmental programming of allergic diseases -- Mind-body interrelationship in DNA methylation -- Neurotrophins in chronic allergic airway inflammation and remodeling -- Pathways underlying afferent signaling of bronchopulmonary immune activation to the central nervous system -- Allergen-induced neuromodulation in the respiratory tract -- Role of microbiome in regulating the HPA axisd and its relevance to allergy -- Autonomic regulation of anti-inflammatory activities from salivary glands -- Mast cell-nerve functional unit: a key component of physiologic and pathophysiologic responses -- Neural and behavioral correlates of food allergy -- Neuroendocrine-immune connection regulates chronic inflammatory disease in allergy -- Itch and the brain.
  • 2015From: Springer
    Ailin Tao, Eyal Rax, editors.
    Allergic Disease Epidemiology -- The Pathogenesis of Allergy: A Brief Introduction -- Genetics and Epigenetic Regulation in Allergic Diseases -- Cross-Reactivity -- From Allergen Extracts to Allergen Genes and Allergen Molecules -- Allergen Gene Cloning -- High Throughput Screening of Allergy -- Surrogate Markers for Allergen-Specific Immunotherapy -- Immune Responses to Allergens in Atopic Disease: Considerations for Bioinformatics -- Antigenicity, Immunogenicity and Allergenicity -- Bioinformatic Classifiers for Allergen Sequence Discrimination -- Strategies for the Modification and Evaluation of Allergenicity -- Bioinformatics Methods to Predict Allergen Epitopes -- Allergen Database.
  • v. 1-6, 2009-2010.From: Springer
    v. 2, 2009From: Springer
    v. 3, 2009From: Springer
    v. 4, 2009From: Springer
    v. 5, 2010From: Springer
    v. 6, 2010From: Springer
    Ruby Pawankar, Stephen T. Holgate, Lanny J. Rosenwasser, editors.
    v. 1. Epigenetics, allergens and risk factors -- v. 2. Classification and pathomechanisms -- v. 3. Clinical manifestations -- v. 4. Diagnosis and health economics -- v. 5. Therapy and prevention -- v. 6. Future perspectives.
  • 2008From: Springer Protocols
    edited by Meinir G. Jones and Penny Lympany.
    Understanding of the molecular mechanisms of allergy / Meinir Jones -- T cell : primary culture from peripheral blood / Monika Raulf-Heimsoth -- Production of T-cell lines / Helga Kahlert -- Production of human T-cell clones / Adrienne Verhoef -- Mapping of human T-cell epitopes of allergens / Thomas Zeiler and Tuomas Virtanen -- Determining MHC restriction of T-cell responses / Mark Larché -- Short-term culture of CD8 cells and intracellular cytokine staining / Beejal Vyas and Alistair Noble -- Isolation, flow cytometric analysis, and suppression assay of CD4+ CD25+ T-regulatory cells / Hayley Jeal -- Monocyte-derived dendritic cells as antigen-presenting cells in T-cell proliferation and cytokine production / Sun-sang J. Sung -- Ultrasensitive ELISA for measurement of human cytokine responses in primary culture / William P. Stefura ... [et al.] -- Quantification of human chemokine production in TLR-stimulated and antigen-specific recall responses / Monique Stinson ... [et al.] -- Standardization of allergen extracts / Jørgen Nedergaard Larsen and Sten Dreborg -- Immunoelectrophoresis for the characterization of allergen extracts / Gitte Nordskov Hansen and Jørgen Nedergaard Larsen -- Conjugation of haptens / Ranulfo Lemus and Meryl H. Karol -- Monoclonal antibodies / Helga Kahlert and Oliver Cromwell -- Purification of antibodies / Per H. Larsson -- Collection of air samples to quantify exposure to airborne allergens / Susan Gordon -- Assay of air sample eluates / Anne Renström and Susan Gordon -- The halogen assay : a new technique for measuring airborne allergen / Euan Tovey ... [et al.] -- Measurement of specific IgG anti-Fel d 1 antibodies / Meinir G. Jones -- The facilitated antigen binding (FAB) assay : a protocol to measure allergen-specific inhibitory antibody activity / James N. Francis -- Microscopic identification and purity determination of pollen grains / Magdalena Rahl -- Biopanning for the characterization of allergen mimotopes / Isabella Pali-Schöll and Erika Jensen-Jarolim -- Identification of mast cells and mast cell subpopulations / Mark Buckley and Andrew F. Walls -- Purification and characterization of mast cell tryptase and chymase from human tissues / Alan R. McEuen and Andrew F. Walls -- Experimental activation of mast cells and their pharmacological modulation / Shaoheng He and Andrew F. Walls -- In situ hybridization / Kayhan T. Nouri-Aria.
  • 2012From: ScienceDirect
    2011From: ClinicalKey
    [edited by] Stephen T. Holgate, Martin K. Church, David H. Broide, Fernando D. Martinez.
    The new edition of Allergy, by Drs. Stephen Holgate, Martin Church, David Broide, and Fernando Martinez, uses an enhanced clinical focus to provide the clear, accessible guidance you need to treat allergy patients. A more consistent format throughout features new differential diagnosis and treatment algorithms, updated therapeutic drug information in each chapter, and additional coverage of pediatric allergies. With current discussions of asthma, allergens, pollutants, drug treatment, and more, as well as access to the full text and illustrations online at, this comprehensive resource is ideal for any non-specialist who treats patients with allergies. Prescribe appropriate therapies and effectively manage patients' allergies using detailed treatment protocols. Identify allergic conditions quickly and easily with algorithms that provide at-a-glance assistance. Explore topics in greater detail using extensive references to key literature.
  • 1905-From: Google Books
    Lubarsch, Otto.
    Also available: Print – v. 1, 1905.
  • von A. von Tschermak.
    PrintStatus: Not Checked OutLane Catalog Record
    Bd. 1. Groundlagen der allgemeinen Physiologie. T. 1. Allgemeine Charakteristik des Lebens physikalische und chemische Beschaffenheit der lebenden Substanz.
  • von Martin Kirschner ... [et al.].
    PrintStatus: Not Checked OutLane Catalog Record
  • begründet von Martin Kirschner.
    PrintStatus: Not Checked OutLane Catalog Record
    Bd. 1. Allgemeine Operations lehre / Gerd Hegemann -- Bd. 2. Die Eingriffe am Gehirnschädel, Gehirn an der Wirbelsäule und am Rückenmark / N. Guleke -- Bd. 4. Gesicht/Gesichtsschädel Kiefer -- Bd. 5. Die Oto-Rhino-Laryngologischen operationen / H.J. Denecke -- Bd. 6, T.1. Die Eingriffe an der Brust und in der Brusthöhle / Alfred Brunner -- Bd. 7, T. 1. Die Eingriffe in der Bauchhöhle / Martin Kirschner -- Bd. 7, T. 2. Die Eingriffe bei den Bauchbüchen / Martin Kirschner -- Bd. 8. Die Eingriffe an den Harnorganen Nebennieren und männlichen Geschlechtsorganen / Leonhard Lurz -- Bd. 9 Gynäkologische Operationen / K.G. Ober [und] H. Meinrenken -- Bd. 10. Die Operationen an den Extremitäten / Werner Wachsmuth.
  • v. 1-[2], 1919-[1926].From: Google Books
    Fulltext (v.2 pt.1 1926)From: Google Books
    Kraus, Friedrich.
    v. 1. Allgemeiner Teil -- v. 2. Besonderer Teil, I. Tiefenperson.
  • 2010From: Springer
    edited by Hillard M. Lazarus, Mary J. Laughlin.
  • 2008From: Springer
    by Thomas Traut.
    Section 1. Overview of enzymes. Introduction to enzymes ; The limits for life define the limits for enzymes ; Enzyme kinetics ; Properties and evolution of allosteric enzymes ; Kinetics of allosteric enzymes -- Section 2. K-type enzymes. Hemoglobin ; Glycogen phosphorylase ; Phosphofructokinase ; Ribonucleotide reductase ; Hexokinase -- Section 3. V-type enzymes. Introduction to V-type enzymes ; G proteins ; Protein kinases.
  • 2012From: Springer Protocols
    edited by Aron W. Fenton.
    Binding techniques to study the allosteric energy cycle -- Kinetic trapping of a key hemoglobin intermediate -- Allosteric coupling between transition metal-binding sites in homooligomeric metal sensor proteins -- Studying the allosteric energy cycle by isothermal titration calorimetry -- Detecting "Silent" Allosteric coupling -- Using mutant cycle analysis to elucidate long-range functional coupling in allosteric receptors -- A review of methods used for identifying structural changes in a large protein complex -- Allosteric mechanisms of g protein-coupled receptor signaling: A structural perspective -- Dynamic light scattering to study allosteric regulation -- Dissecting the linkage between transcription factor self-assembly and site-specific DNA binding: The role of the analytical ultracentrifuge -- Fluorescence correlation spectroscopy and allostery: The case of GroEL -- The morpheein model of allostery: Evaluating proteins as potential morpheeins -- Combining NMR and molecular dynamics studies for insights into the allostery of small GTPase-protein interactions -- Hydrogen-deuterium exchange study of an allosteric energy cycle -- Ensemble properties of network rigidity reveal allosteric mechanisms -- An in vivo approach to isolating allosteric pathways using hybrid multimeric proteins -- Mutations in the GABA(A) receptor that mimic the allosteric ligand etomidate -- Allosteric regulation of human liver pyruvate kinase by peptides that mimic the phosphorylated/dephosphorylated N-terminus -- In silico-screening approaches for lead generation: Identification of novel allosteric modulators of human-erythrocyte pyruvate kinase -- Identification of allosteric-activating drug leads for human liver pyruvate kinase -- A critical evaluation of correlated mutation algorithms and coevolution within allosteric mechanisms -- The advantage of global fitting of data involving complex linked reactions -- Predicting binding sites by analyzing allosteric effects.
  • 2015From: Karger
    volume editors, Dimitrios Ioannides, Antonella Tosti.
    Normal and aging hair biology and structure 'aging and hair' -- Evaluation of hair loss -- Scalp dermoscopy or trichoscopy -- Androgenetic, diffuse and senescent alopecia in men: practical evaluation and management -- Female pattern hair loss -- Hair loss in children -- Alopecia areata -- Primary scarring alopecias -- Molecular genetics of alopecias -- Alopecias due to drugs and other skin and systemic disorders -- Effect of ultraviolet radiation, smoking and nutrition on hair -- Hair care and dyeing -- Age-related hair pigment loss -- Ethnic hair disorders -- Advances in hair transplantation: longitudinal partial follicular unit transplantation.
  • 2016From: Springer
    Adam Wanner, Robert A. Sandhaus, editors.
    Alpha-1- Antitrypsin and the Serpins -- Alpha-1 Antitrypsin: The protein -- Misfolding and Polymerisation of Alpha1-Antitrypsin ? Conformational Pathology and Therapeutic Targeting -- Managing the Adaptive Proteostatic Landscape: Restoring Resilience in Alpha-1 Antitrypsin Deficiency -- United States Targeted Detection Program for Alpha-1 Antitrypsin Deficiency -- Lung Disease of Alpha-1 Antitrypsin Deficiency -- Alpha-1-Antitrypsin Deficiency: Role in Health and Disease -- Alpha-1 Antitrypsin as a Therapeutic Agents for Conditions not Associated with Alpha-1 Antitrypsin Deficiency -- The Alpha-1 Constellation of Voluntary Health Organizations as a Paradigm for Confronting Other Rare Diseases.
  • by Nicholas Everett.
    The Alphabet of Galen is a critical edition and English translation of a text describing, in alphabetical order, nearly three hundred natural products - including metals, aromatics, animal materials, and herbs - and their medicinal uses. A Latin translation of earlier Greek writings on pharmacy that have not survived, it circulated among collections of 'authorities' on medicine, including Hippocrates, Galen of Pergamun, Soranus, and Ps. Apuleius. This work presents interesting linguistic features, including otherwise unattested Greek and Latin technical terms and unique pharmacological descriptions. Nicholas Everett provides a window onto the medieval translation of ancient science and medieval conceptions of pharmacy. With a comprehensive scholarly apparatus and a contextual introduction, The Alphabet of Galen is a major resource for understanding the richness and diversity of medical history.
  • 2013From: Cambridge
    edited by Liane Deligdisch, MD, professor of pathology and obstetrics-gynecology and reproductive science, the Mount Sinai Medical Center and School of Medicine, New York, NY, USA, Nathan G. Kase, MD, professor in obstetrics, gynecology, and reproductive sciences, professor of endocrinology and dean emeritus, the Mount Sinai School of Medicine, New York, NY, USA, Carmel J. Cohen, MD, professor of obstetrics, gynecology, and reproductive science, professor of gynecologic oncology, Ruttenberg Cancer Center, the Mount Sinai School of Medicine, New York, NY, USA.
    1. Normal human ovary part I: reproductive and endocrine functions / Nathan G. Kase -- 2. Normal human ovary part II: how steroid hormones work / Nathan G. Kase -- 3. Gonadal dysgenesis: ovarian function and reproductive health in Turner syndrome / Paul Saenger and David Rodriguez-Buritica -- 4. Pathology of benign and malignant ovarian epithelial tumors / Liane Deligdisch -- 5. Ovarian tumors of borderline malignancy / Peter Schlosshauer -- 6. Precursors of ovarian epithelial carcinoma / Liane Deligdisch -- 7. Peritoneal serous and tubal cancer / Anna Laury, Eric C. Huang, Christopher P. Crum and Jonathan Hecht -- 8. Pathology of ovarian germ cell tumors / Liane Deligdisch -- 9. Metastatic ovarian tumors / Angelica Mares and Liane Deligdisch -- 10. Genetic etiology of sporadic ovarian cancer / Ellen L. Goode, Mine S. Cicek, Catherine M. Phelan and Brooke L. Fridley -- 11. Polycystic ovary syndrome / Nathan G. Kase -- 12. Endometriosis of the ovary / Luciano G. Nardo, Ioannis Gryparis and Sree Durga Patchava -- 13. New advances and new horizons in assisted reproduction / Yuval Bdolah and Neri Laufer -- 14. Endometriosis and ovarian cancer / Douglas N. Brown, Tanja Pejovic and Farr R. Nezhat -- 15. Laparoscopic surgery of the benign ovary and new laparoscopic developments / Michel Canis, M. Gage, R. Botchorishvili and Antoine Maurice Bruhat -- 16. Ultrasound, MRI, CT, and PET imaging of ovarian cancer / William L. Simpson, Jr and Lale Kostakoglu -- 17. Ovarian cysts and tumors of the fetus, child, adolescent, and young adult / Albert Altchek and Liane Deligdisch -- 18. Should the ovaries be removed during a hysterectomy? / Michael S. Broder and Wendy C. Hsiao -- 19. The aging ovary / Norbert Gleicher and David H. Barad -- 20. Menopause / Nathan G. Kase -- 21. Clues to ovarian tumors: new concepts of symptoms, signs, syndromes, and paraneoplastic syndromes / Albert Altchek and David Fishman -- 22. When is ovarian carcinoma discovered in stage I? / Liane Deligdisch and Albert Altchek -- 23. Early detection of ovarian cancer / Christina E. Curtin, Pierre S. Gordon and David Fishman -- 24. Laparoscopic evaluation and management of adnexal masses and ovarian cancer / Farr R. Nezhat, Jason Sternchos, Tamara Finger and Tanja Pejovic -- 25. Ovarian cancer: the initial laparotomy / Jamal Rahaman, Valentin Kolev and Carmel J. Cohen -- 26. Chemotherapy of ovarian cancer / Ramez N. Eskander and Philip J. Di Saia -- 27. Intraperitoneal chemotherapy / Maurie Markman -- 28. Malignant germ cell tumors and sex cord stromal tumors in adults and children / Jubilee Brown and David M. Gershenson -- 29. Palliative care / Katharine Batt and Cardinale B. Smith.
  • Ricardo Andres Valenzuela.
    Down Syndrome and Fragile X Syndrome are disorders of mental retardation that are characterized by cognitive impairments and changes to other physical characteristics. A goal in the study of these diseases has been to understand the mechanisms that underlie the cognitive impairments present in these two disorders of mental retardation. A great deal of effort has been made to study synaptic function and structure in these disorders of mental retardation in order to determine whether there are any alterations present. Alterations to synaptic structure and function present during these disorders may give insight to the neural basis of the cognitive impairments that are characteristic of this disorder of mental retardation. An area of the brain that may be affected by these disorders is the hippocampus. This area of the brain has been extensively studied for its role in memory and alterations to synaptic function and structure may underlie some of the memory deficits present in these disorders of mental retardation. Both Down Syndrome patients and Fragile X Syndrome patients have deficits in their performance on memory tests. Down Syndrome patients also have a reduction in the number of neurons present in the hippocampus (Carlesimo et al., 1997). Fragile X Syndrome patients had structural abnormalities in the hippocampus including an enlargement of ventricular spaces (Jakala et al., 1997). Synaptic function and structure in the hippocampus of mouse models of Down Syndrome and Fragile X Syndrome were studied in order to determine this region of the brain was affected. Electrophysiology recordings in area CA3 of the hippocampus of the Ts65Dn Down Syndrome mouse model indicated there were disruptions to synaptic connectivity, decreases in excitatory and inhibitory synaptic transmission, and also a reduction in intrinsic interneuron activity. Imaging studies of CA3 in the Ts65Dn mouse did not show alterations to the number of synapses or structure of synapses suggesting that the alterations found with electrophysiology recordings are the result of functional changes to synapses. Electrophysiology study of the hippocampus in mouse models of Fragile X Syndrome has shown that inhibitory function was generally intact but that excitatory axons from neurons that lacked the Fragile X Mental Retardation Protein (FMRP) were less competitive at forming synapses in a mosaic expression system of the Fmr1 gene the lack of which causes the disease. These studies indicate that alterations to synaptic structure and function are present in the hippocampus of these mouse models of mental retardation. The differences however, were not the same in Down Syndrome and Fragile X Syndrome mouse models. Nonetheless, it is possible that the changes to synaptic function found in both of these mouse models leads to altered network function in the hippocampus which may, in turn, be the underlying cause of the memory deficits present in these disorders of mental retardation. The data presented in these studies indicate that the study of these mouse models of mental retardation can give insight to alterations caused by these disorders of mental retardation which may also lead to the development of new treatments.
  • 2008From: Springer
    edited by B. Andrew Lustig, Baruch A. Brody, Gerald P. McKenny.
  • Brandon E. Johnson.
    Ion channels coordinate the movement of ions across biological membranes in response to a diversity of cellular signals to regulate most if not all aspects of physiology. The large-conductance Ca2+- and voltage-activated potassium (BK) channel is widely expressed across tissues and functions to repolarize action potentials, regulate smooth muscle tone and endocrine function, and tune auditory hair cells. In all tissues, BK channels provide a functional link between cytosolic Ca2+ and membrane excitation. Extensive alternate splicing of the slo-1 gene, encoding the BK channel, significantly diversifies channel function. We identified all twelve predicted BK channel splice variants expressed by the nematode Caenorhabditis elegans, and measured the Ca2+ and voltage dependence for each. Alternate exons encode portions of two regions of the cytoplasmic tail: the RCK domain, important for Ca2+ coordination, and an unstructured region, termed the C-linker. Using the patch clamp technique, we determined that alternate splicing across multiple sites diversifies activation kinetics and Ca2+ sensitivity by manipulating the functional interaction between the RCK domain and C-linker. We recovered two slo-1 alleles (pg34 and pg52) that contain point-mutations near an alternative splice site in the C-linker from a mutant screen. Using real-time PCR, we determined that both mutations change slo-1 splice variant expression profiles. The pg34 mutation encodes an A698T substitution, and the pg52 mutation is located in an intron. When heterologously expressed, the A698T mutation changes BK channel Ca2+ sensitivity in specific splice variant backgrounds by disrupting the functional connection between the C-linker and the RCK domain. Using in vivo electrophysiology, we determined that the pg34 mutation reduces but does not abolish BK channel function in C. elegans neurons. These results suggest that alternate splicing of slo-1 modulates the functional connection between the RCK domain and the C-linker of the BK channel to establish a proper balance between intracellular Ca2+ and membrane excitation in a variety of cell type and physiological conditions.
  • Jacob Samuel Brenner.
    PrintStatus: Not Checked OutLane Catalog Record
  • 2016From: Springer
    Eric T. Wong, editor.
    This concise text provides a complete overview of alternating electric fields therapy -- also known as tumor treating fields -- for glioblastoma and other types of solid tumor malignancies. Readers are given a fundamental understanding of this novel anti-cancer treatment modality by learning from clinical trial data as well as the physical and cell biology effects on tumor cells when alternating electric fields are applied both in vitro and in vivo. Chapters illustrate the physics behind electric field propagation in space and other media. This is followed by a review of our current understanding of the electric field effects on dividing cells - including the disruption of cytokinesis, proper chromosome segregation and activation on the cell surface chaperons that induce immunogenic cell death. Data from phase III trials for the treatment of recurrent and newly diagnosed glioblastomas are included, as well as some of the ancillary post hoc analyses that were performed by various investigators. The remainder of the chapter covers other solid tumor malignancies, including non-small cell lung cancer, pancreatic cancer and ovarian cancer, as this treatment modality is being applied to systemic malignancies. Alternating Electric Fields Therapy in Oncology offers oncologists, neurologists, radiation oncologists, biomedical engineers, cell biologists and mitosis researchers the fundamentals needed for clinical practice.
  • 2010From: Springer
    Moulay Alaoui-Jamali, editor.
    Overview of efficacy and limitation of standard and targeted therapy for malignant disease using lung cancer as a case study -- Overview of current TCM practice and potential impacts on conventional therapies -- Complementary and alternative medicine for cancer care in India: basic and clinical perspective -- Esophageal cancer -- Gastric cancer -- Colorectal cancer -- Liver cancer -- Pancreatic cancer -- Breast cancer -- Ovarian cancer -- Prostate cancer -- Kidney cancer -- Bladder cancer -- Brain cancer -- Complementary and alternative treatments for the management of cancer-related fatigue -- Complementary and alternative treatments for the management of cancer-related pain -- Challenges conducting clinical trials with herbal products in oncology -- Herbal product-drug interactions from a pharmacological perspective -- Patient-physician relationship: creating an optimal healing environment -- Legal issues in alternative treatment of cancer -- Intellectual property for alternative medicine -- Chemical-biology of natural products from medicinal plants for cancer therapy -- Flavonoids in cancer prevention and therapy: chemistry, pharmacology, mechanisms of action, and perspectives for cancer drug discovery -- Marine natural products and their synthetic derivatives for cancer therapy -- Natural product-like scaffolds for molecular dissection of macromolecular interactions and new therapeutic applications -- Mining natural product-derived molecules against cancer targets: the case of the androgen receptor in prostate cancer.
  • 2006From: ScienceDirect
    edited by Cynthia Robbins-Roth.
    A scientist gone bad : how I went from the bench to the boardroom / Cynthia Robbins-Roth -- Technical writing : making sense out of manuals / Clayton R. Randall (second edition updated by Cynthia Robbins-Roth) -- Science writing : communicating with the masses / Sue Goetinck Ambrose -- Creating a publishing empire : how I gave up academic and became an entrepreneurial editor / Roger Longman -- Business information services : providing the data for industry / Mark D. Dibner -- Becoming a venture capitalist / Deepa Pakianathan -- Investment banking : dreams and reality / Peter Drake (second edition updated by Cynthia Robbins-Roth) -- How I became an analyst : science-based investment advising / Mary Ann Gray -- Entrepreneur and company founder : starting your own company and surviving / Ron Cohen -- Business development : making deals with science / Ronald Pepin -- The growth of a manager : from pure research to policy administration / Philip W. Hammer -- Regulatory affairs : keeping product development on track / Elizabeth D. Moyer -- Patent law careers : protecting the intellectual property of science / Alexandra J. Baran -- Entering biomedical and scientific consulting / Robert Roth -- Sales and marketing : so you want to sell? / Erin Hall Meade -- From doing research to moving research : my life in tech transfer / Paula Szoka -- Corporate communications : helping companies sell their stories / Tony Russo -- Executive search : the hunt for exceptional talent / Bente Hansen -- Consultant to the stars : advising CEOs for fun and profit / Carol Hall -- Biomedical consultant : specializing in technology assessment, strategic planning, and grant writing / Gail Schechter -- Science and public policy : translating between two worlds / David Applegate -- Economic development advisor : building a biotech industry for an entire country / Gina Lento -- Government agencies : directing science in the military / Genevieve Haddad -- Appendix : information resources about alternative careers for scientists / Cynthia Robbins-Roth.
  • edited by Benjamin J. Blencowe, Brenton R. Graveley.
  • PrintStatus: Not Checked OutLane Catalog Record
  • 2015From: Springer
    Nejat Erverdi, Melih Motro.
    This book describes a new method of alveolar distraction osteogenesis that offers important advantages and can be used for the treatment of various orthopedic abnormalities and congenital malformations. Detailed guidance is provided on selection of patients suitable for alveolar distraction, including those with cleft lip and palate, skeletal class II malocclusions, and cystic lesions involving the alveolus. All aspects of treatment using the ArchWise distraction appliance are then covered, including technical preparation, surgical set-up and osteotomies, docking site surgery, orthodontic finishing, implant placement, and prosthetic restorations. Relevant information is also included on the principles of distraction osteogenesis and bone histology and quality after the procedure. The book concludes with helpful case presentations covering different scenarios in which ArchWise distraction of alveolar bone is appropriate.
  • David Ludwig, MD, PhD.
    PrintStatus: Not Checked OutLane Catalog Record
    "Inspired by the New York Times op-ed "Always Hungry," ALWAYS HUNGRY? will change everything readers ever thought about weight loss, diet, and health. Groundbreaking new research shows that calorie counting does not work for weight loss: one diet causes weight gain whereas another diet with the same calorie count doesn't. It's your fat cells that are to blame for causing excessive hunger and increased weight. By eating the wrong foods, our fat cells are triggered to take in too many calories for themselves, setting off a dangerous chain reaction of increased appetite and a slower metabolism. Now, Harvard Medical School's David Ludwig, MD, PhD, offers an impeccably researched diet that will turn dieting on its head, teaching readers to reprogram their fat cells, tame hunger, boost metabolism, and lose weight--for good"-- Provided by publisher.
  • 2006From: Springer
    M. Jucker ... [et al.], eds.
  • Margaret Lock.
    PrintStatus: Not Checked OutLane Catalog Record
    Based on a careful study of the history of Alzheimer's disease and extensive in-depth interviews with clinicians, scientists, epidemiologists, geneticists, and others, Margaret Lock highlights the limitations and the dissent implicated in this approach. She stresses that one major difficulty is the well-documented absence of behavioral signs of Alzheimer's disease in a significant proportion of elderly individuals, even when Alzheimer neuropathology is present in their brains. This incongruity makes it difficult to distinguish between what counts as normal versus pathological and, further, makes it evident that social and biological processes contribute inseparably to aging. Lock argues that basic research must continue, but it should be complemented by a realistic public health approach available everywhere that will be more effective and more humane than one focused almost exclusively on an increasingly frenzied search for a cure.
  • 2016From: ClinicalKey
    Amy R. Borenstein, Ph.D, M.P.H., and James A. Mortimer, Ph.D., and James Mortimer, University of South Florida, Department of Epidemiology and Biostatistics, Department of Neurology, Tampa, FL, USA.
    The "first" case -- Clinical appearance, progression, and classification -- Epidemiologic definition of a case -- Neuropathology of Alzheimer's disease -- The threshold model of dementia -- The prevalence of Alzheimer's disease -- The incidence of Alzheimer's disease -- Survival and mortality in Alzheimer's disease -- Introduction to the analytic epidemiology of Alzheimer's disease -- Family history, genetics, and down syndrome -- Early-life factors -- Traumatic brain injury -- Cigarette smoking and alcohol consumption -- Vascular disease -- Diet -- Physical activity -- Cognitive activity -- Social engagement -- Nonsteroidal anti-inflammatory drugs, hormone replacement therapy, and anticholinergic medications -- Prodromal markers of disease or causal risk factors? Depression, olfaction, and subjective memory complaints -- Fluid, imaging, and cognitive biomarkers -- Risk assessment and prevention of Alzheimer's disease -- Summary and recommendations.
  • 2007From: Springer
    edited by Sangram S. Sisodia and Rudolph E. Tanzi.
  • 2012From: Karger
    volume editors, H. Hampel, M.C. Carrillo.
    The global impact of Alzheimer's disease / M.C. Carrillo, W. Thies, L.J. Bain -- The genetics of Alzheimer's disease / M.C. Schu ... [et al.] -- Current conceptual view of Alzheimer's disease / K. Herrup -- Neuropathological basis of Alzheimer's disease and Alzheimer's disease diagnosis / J.A. Schneider ... [et al.] -- Diagnostic tools : fluid biomarkers for Alzheimer's disease / H. Zetterberg, H. Hampel, K. Blennow -- MRI-and PET-based imaging markers for the diagnosis of Alzheimer's disease / S. Teipel ... [et al.] -- Changing diagnostic concepts of Alzheimer's disease / G.M. McKhann, M.S. Albert, R.A. Sperling -- Pharmacological treatment of Alzheimer's disease / L.S. Schneider -- Regulatory requirements on clinical trials in Alzheimer's disease / K. Broich ... [et al.] -- Perspectives on Alzheimer's disease : past, present and future / Z.S. Khachaturian.
  • 2010From: Springer Protocols
    edited by Erik D. Roberson.
    Contemporary Approaches to Alzheimer's Disease and Frontotemporal Dementia / Erik D. Roberson -- Preparing Synthetic Aβ in Different Aggregation States / W. Blaine Stine, Lisa Jungbauer, Chunjiang Yu, Mary Jo LaDu -- Isolation of Low-n Amyloid β-Protein Oligomers from Cultured Cells, CSF, and Brain / Ganesh M. Shankar, Alfred T. Welzel, Jessica M. McDonald, Dennis J. Selkoe, Dominic M. Walsh -- Detecting Aβ*56 Oligomers in Brain Tissues / Mathew A. Sherman, Sylvain E. Lesné -- Assessing Aβ Aggregation State by Atomic Force Microscopy / Justin Legleiter -- Measuring APP Carboxy-Terminal Fragments / Luke A. Esposito -- Detection of APP Intracellular Domain in Brain Tissue / Sanjay W. Pimplikar, Anupama Suryanarayana -- Cell-Based Assays for Regulators of Tau Biology / Umesh K. Jinwal, Chad A. Dickey -- Split GFP Complementation Assay for Quantitative Measurement of Tau Aggregation In Situ / Wanjoo Chun, Geoffrey S. Waldo, Gail V. Johnson -- Apolipoprotein E Expression and Purification / Yvonne Newhouse, Karl H. Weisgraber -- Aβ Toxicity in Primary Cultured Neurons / Adriana Ferreira, Roxana C. Sinjoanu, Alexandra Nicholson, Sara Kleinschmidt -- Manipulation of Gene Expression in the Central Nervous System with Lentiviral Vectors / Binggui Sun, Li Gan -- Selecting a Mouse Model of Alzheimer's Disease / Jeannie Chin -- Monitoring Spatial Learning and Memory in Alzheimer's Disease Mouse Models Using the Morris Water Maze / Kimberly Scearce-Levie -- Step-by-Step In Situ Hybridization Method for Localizing Gene Expression Changes in the Brain / Jorge J. Palop, Erik D. Roberson, Inma Cobos -- Real-Time Visualization of Axonal Transport in Neurons / Yasuko Osakada, Bianxiao Cui -- Quantifying Biomarkers of Cognitive Dysfunction and Neuronal Network Hyperexcitability in Mouse Models of Alzheimer's Disease: Depletion of Calcium-Dependent Proteins and Inhibitory Hippocampal Remodeling / Jorge J. Palop, Lennart Mucke, Erik D. Roberson -- Epigenetic Changes in the Brain: Measuring Global Histone Modifications / Gavin Rumbaugh, Courtney A. Miller.
  • 2016From: Springer
    Jack C. de la Torre.
    Chapter 1. How does Alzheimer's begin and who gets it? -- Chapter 2. Forming memories -- Chapter 3. Masquerading as dementia -- Chapter 4. Alzheimer's -- then and now -- Chapter 5. Unproven hypotheses on the cause of Alzheimer's -- Chapter 6. Other hypotheses on the cause of Alzheimer's disease -- Chapter 7. Alzheimer noise -- Chapter 8. Social contract and Alzheimer's -- Chapter 9. Genetics of Alzheimer's -- Chapter 10. Powering the brain -- Chapter 11. Pharmaceuticals and Alzheimer's -- Chapter 12. Alzheimer vascular risk factors -- Chapter 13. The Good, The Bad and The Ugly of Advanced Aging -- Chapter 14. A Personal Account of How a Scientific Hypothesis Blooms Into a Life of Its Own -- Chapter 15. Clinical tools to detect and predict individuals at risk of Alzheimer's -- Chapter 16. The turning point for Alzheimer's -- Chapter 17. How poor brain blood flow promotes Alzheimer's disease -- Chapter 18. Interventions that may increase cerebral blood flow -- Chapter 19. Great Expectations -- Chapter 20. A road to new thinking.
  • Cheryl Iverson (chair) [and others].
    PrintStatus: Not Checked OutLane Catalog Record
    Types of articles -- Manuscript preparation -- References -- Visual presentation of data -- Ethical and legal considerations -- Editorial assessment and processing -- Grammar -- Punctuation -- Plurals -- Capitalization -- Correct and preferred usage -- Non-English words, phrases, and accent marks -- Medical indexes -- Abbreviations -- Nomenclature -- Eponyms -- Greek letters -- Units of measure -- Numbers and percentages -- Study design and statistics -- Mathematical composition -- Typography -- Manuscript editing and proofreading -- Glossary of publishing terms -- Resources.
    Also available: Print – 2007
  • 2016From: WHO
    World Health Organization.
    This report presents a summary of methods and results of the latest World Health Organization (WHO) global assessment of ambient air pollution exposure and the resulting burden of disease. To date, air pollution -- both ambient (outdoor) and household (indoor) -- is the biggest environmental risk to health, carrying responsibility for about one in every nine deaths annually. Ambient (outdoor) air pollution alone kills around 3 million people each year, mainly from noncommunicable diseases. Air pollution continues to rise at an alarming rate, and affects economies and people's quality of life; it is a public health emergency. Interventions and policies for tackling air pollution issues exist and have been proven to be effective. Air pollution has also been identified as a global health priority in the sustainable development agenda. The role of the health sector is crucial, and there is a need to engage with other sectors to maximize the co-benefits of health, climate, environment, social and development. Saving people's lives is the overarching aim to implement policies aiming at tackling air pollution in the health, transport, energy, and urban development sectors.
  • Efforts to mitigate ambulance diversion have been effective, but questions remain for future progress.
  • 2015From: Springer
    Paresh Wankhade, Kevin Mackway-Jones, editors.
    Introduction: Understanding the Management of Ambulance Services / Paresh Wankhade and Kevin Mackway-Jones -- Historical Perspectives in the Ambulance Service / Alexander Pollock -- A Strategy for Managing Quality in Ambulance Services / Mary Peters, Steve Barnard, Michael Dorrian and Kevin Mackway-Jones -- Management of Emergency Demand / Bob Williams -- Ethical Commissioning of Emergency Ambulance Services / Mark Docherty -- Organisational and Professional Cultures: An Ambulance Perspective / Paresh Wankhade, James Radcliffe and Geoffrey Heath -- Leadership and System Thinking in the Modern Ambulance Service / Andy Newton and Graham Harris -- Ambulance Service Modernisation / Robert Till and Anthony Marsh -- Interoperability and Multiagency Cooperation / John Stephenson -- Responding to Diversity and Delivering Equality in Prehospital Care: Statutory Responsibilities, Best Practice and Recommendations / Viet-Hai Phung, Karen Windle and A. Niroshan Siriwardena -- Dealing with the Austerity Challenge / Robert Till and Anthony Marsh -- The Ambulance Service of the Future / Mark Docherty, Andrew Carson and Matthew Ward -- Future Perspectives for the UK Ambulance Services: Evolution Rather than Revolution / Kevin Mackway-Jones and Paresh Wankhade -- International Perspectives: Australian Ambulance Services in 2020 / Paul M Middleton -- International Perspectives: South African Ambulance Services in 2020 / Craig Vincent-Lambert -- International Perspectives: Finnish Ambulance Services in 2020 / Juha Jormakka and Simo Saikko -- Index.
  • 2010From: Springer
    Nanette F. Santoro, Genevieve Neal-Perry, editors.
    Amenorrhea: A Case-Based Clinical Guide is a comprehensive review of the current knowledge regarding normal female reproductive physiology. Replete with interesting case vignettes and providing diagnostic algorithms and therapeutic strategies for amenorrhea, Amenorrhea: A Case-Based Clinical Guide is divided into three sections. The first section is composed of two chapters that provide a thorough review of basic science and clinical knowledge about the organ systems responsible for normal physiology of the menstrual cycle. The second section includes discussion about menstrual cycle disruption as it relates to hypothalamic-pituitary dysfunction, surgical and natural menopause, genetic defects, premature ovarian failure/insufficiency and the effects of caloric excess and restriction. The third section offers an update on the physiological effects of prolonged amenorrhea induced surgically or by hypothalamic dysfunction and also includes an original chapter that focuses solely on the impact of race and ethnicity on the prevalence and diagnosis of amenorrhea. Amenorrhea: A Case-Based Clinical Guide brings together chapters from renowned experts who offer state-of-the-art, clinically useful information in a case-based, reader-friendly fashion. This title will be a welcome addition to the bookshelves of all clinicians who practice in women's health settings.
  • 2017From: Pediatric Care Online
    Thomas K. McInerny, editor in chief ; co-editors, Henry M. Adam, Deborah E. Campbell, Thomas G. DeWitt, Jane Meschan Foy, Deepak M. Kamat ; tools editors, Rebecca Baum and Kelly J. Kelleher.
    Pt. 1: Delivering pediatric health care -- Pt. 2: Principles of care -- Sect. 1: Pediatric assessment -- Sect. 2: Preventive pediatrics -- Sect. 3: General management of children with health and behavioral problems -- Sect. 4: Care of special population -- Pt. 3: Maternal and fetal health: effect on pregnancy outcomes and perinatal health -- Pt. 4: Care of healty and high-risk infants -- Sect. 1: Routine care issues -- Sect. 2: Assessment and physical examination of the newborn -- Sect. 3: Neonatal medical conditions -- Sect. 4: Perinatal care: caring for the high-risk infant -- Sect. 5: Neonatal outcomes -- Sect. 6: Supporting families during perinatal illness and death -- Pt. 5: Adolescence -- Pt. 6: Presenting signs and symptoms -- Pt. 7: Specific clinical problems -- Pt. 8: Critical situations.
  • Richard F. Groves and Henriette Anne Klauser.
    PrintStatus: Not Checked OutLane Catalog Record
  • by Earnest Albert Hooton ; with the collaboration of the Statistical Laboratory of the Division of Anthropology, Harvard University ...
    PrintStatus: Not Checked OutLane Catalog Record
  • King, John; Felter, Harvey Wickes; King, John.
    PrintStatus: Not Checked OutLane Catalog Record
  • W. Michael Byrd, Linda A. Clayton ; with a foreword by Dr. Robert J. Blendon.
    PrintStatus: Not Checked OutLane Catalog Record
    V. 1. A Medical history of African Americans and the problem of race : beginnings to 1900
  • PrintStatus: Not Checked OutLane Catalog Record
    Also available: Print – 1989/90-2009
  • v. 1-3.From: Google Books
    Fulltext (v. 3)From: Google Books
    Beach, W.
    Also available: Print – v. 1-3.
  • 2006-From: PsychiatryOnline
    [American Psychiatric Association].
    "American Psychiatric Association (APA) practice guidelines provide evidence-based recommendations for the assessment and treatment of psychiatric disorders. Practice guidelines are intended to assist in clinical decision making by presenting systematically developed patient care strategies in a standardized format." Includes a Legacy Collection with a caveat that materials may not be current.
  • 2015From: PsychiatryOnline
    edited by David C. Steffens, Dan G. Blazer, Mugdha E. Thakur.
    Demography and epidemiology of psychiatric disorders in late life / Celia F. Hybels, Ph.D., and Dan G. Blazer, M.D., Ph.D -- Physiological and clinical considerations of geriatric patient care / Robert M. Kaiser, M.D., M.H.Sc -- Genomics in geriatric psychiatry / Aaron M. Koenig, M.D., and Robert A. Sweet, M.D -- The psychiatric interview of older adults / Dan G. Blazer, M.D., Ph.D -- Use of the laboratory in the diagnostic workup of older adults / Sophia Wang, M.D., Mugdha Thakur, M.D., and P. Murali Doraiswamy, M.B.B.S., F.R.C.P -- Neuropsychological assessment of dementia / Kathleen A. Welsh-Bohmer, Ph.D., AND Deborah K. Attix, Ph.D -- Delirium / Jane S. Saczynski, Ph.D., AND Sharon K. Inouye, M.D., M.P.H -- Dementia and mild neurocognitive disorders / Eitan Z. Kimchi, M.D., and Constantine G. Lyketsos, M.D., M.H.S -- Mood disorders / David C. Steffens, M.D., M.H.Sc -- Bipolar disorder in late life / John L. Beyer, M.D -- Schizophrenia spectrum and other psychotic disorders / Jeanne E. Maglione, M.D., Ph.D., Ipsit V. Vahia, M.D., and Dilip V. Jeste M.D -- Anxiety disorders / Eric J. Lenze, M.D., Jan Mohlman, Ph.D., and Julie Loebach Wetherell, Ph.D -- Somatic symptom and related disorders / Marc E. Agronin, MD -- Sexuality and aging / Marc E. Agronin, MD -- Bereavement / Moria J. Smoski, Ph.D., Stephanie T. Jenal, Ph.D., and Larry W. Thompson, Ph.D -- Sleep and circadian rhythm disorders / Andrew D. Krystal, M.D., M.S., and Mugdha Thakur, M.D -- Alcohol and drug problems / Shahrzad Mavandadi, Ph.D., and David W. Oslin, M.D -- Personality disorders / Thomas E. Oxman, M.D -- Agitation and suspiciousness / Mugdha E. Thakur, M.D., and Lisa P. Gwyther, M.S.W -- Psychopharmacology / Benoit H. Mulsant, M.D., and Bruce G. Pollock, M.D., Ph.D -- Electroconvulsive therapy and other forms of brain stimulation / Richard D. Weiner, M.D., Ph.D., and Mustafa M. Husain, M.D -- Nutrition and physical activity / Kathryn Porter Starr, Ph.D., R.D., Connie Watkins Bales, Ph.D., R.D., and Martha E. Payne, Ph.D., R.D., M.P.H -- Individual and group psychotherapy / Moria J. Smoski, Ph.D., and Patricia A. Arean, Ph.D -- Working with families of older adults / Lisa P. Gwyther, M.S.W., and Diane E. Meglin, M.S.W -- Clinical psychiatry in the nursing home / Joel E. Streim, M.D.
  • 2014From: PsychiatryOnline
    edited by Robert E. Hales, Stuart C. Yudofsky, Laura Weiss Roberts ; with foreward by David J. Kupfer.
  • 2009From: PsychiatryOnline
    edited by Alan F. Schatzberg and Charles B. Nemeroff.
  • 2015From: PsychiatryOnline
    edited by Marc Galanter, M.D., Herbert D. Kleber, M.D., Kathleen T. Brady, M.D., Ph.D..
    Section I. The basis of addictive disorders -- Neurobiology of addiction -- Genetics of addiction -- Epidemiology of addiction -- Cross-cultural aspects of addiction -- Section II. The nature of treatment -- Science in the treatment of substance abuse -- Assessment of the patient -- Screening and brief intervention -- Patient placement criteria -- "Recovery" in chronic care disease management -- Section III. Specific drugs of abuse -- Neurobiology of alcohol use disorder -- Treatment of alcohol intoxication and alcohol withdrawal -- Neurobiology of stimulants -- Clinical management: cocaine -- Clinical management: methamphetamine -- Hallucinogens and club drugs -- Tobacco use disorder -- Benzodiazepines and other sedatives and hypnotics -- Treatment of anabolic-androgenic steroid-related disorders -- Neurobiology of opiates and opioids -- Opioid detoxification -- Methadone and buprenorphine maintenance -- Opioid antagonists -- Neurobiology of marijuana -- Treatment of cannabis use disorder -- Section IV. Treatment modalities -- Psychodynamic psychotherapy -- Cognitive-behavioral therapies -- Motivational enhancement -- Twelve-step facilitation -- Contingency management -- Network therapy -- Group therapy -- Family therapy -- Section V. Rehabilitation settings -- Inpatient treatment -- Therapeutic communities -- Community-based treatment -- History of alcoholics anonymous and the experiences of patients -- Psychological mechanisms in alcoholics anonymous -- Outcomes research on twelve-step programs -- Section VI. Special populations -- Women and addiction -- Perinatal substance use disorders -- Adolescent substance use disorders: epidemiology, neurobiology, and screening -- Adolescent substance use disorders: transition to substance abuse, prevention, and treatment -- Psychiatric consultation in pain and addiction -- Prevention of prescription drug abuse -- HIV/AIDS and hepatitis C -- Substance use disorders among physicians -- Substance use issues among gay, lesbian, bisexual, and transgender people -- Minorities -- Section VII. Special topics -- Testing to identify recent drug use -- Medical education on addiction -- Prevention of substance abuse -- Forensic addiction psychiatry -- Substance abuse and mental illness -- Substance-related and addictive disorders.
  • edited by Marc Galanter, Herbert D. Kleber.
    PrintStatus: Not Checked OutLane Catalog Record
    Part 1 : The basis of addictive disorders -- Neurobiology of addiction / George F. Koob -- Genetics of addiction / Joel Gelernter, Henry R. Kranzler -- Epidemiology of addiction / Judith S. Brook, Kerstin Pahl, Elizabeth Rubenstone -- Cross-cultural aspects of addiction / Nady el-Guebaly -- Part 2 : The nature of treatment -- Assessment of the patient / Shelly F. Greenfield, Grace Hennessy -- Patient placement criteria / David Mee-Lee, David R. Gastfriend -- Evolution in addiction treatment concepts and methods / A. Thomas McLellan -- Part 3 : Specific drugs of abuse -- Alcohol -- Neurobiology of alcohol / Clifford M. Knapp, Domenic A. Ciraulo, Henry R. Kranzler -- Clinical management of alcohol abuse and dependence / Hugh Myrick, Tara Wright -- Stimulants -- Neurobiology of stimulants / Margaret Haney -- Clinical management : cocaine / Thomas R. Kosten, Mehmet Sofuoglu, Tracie J. Gardner -- Clinical management : methamphetamine / Richard A. Rawson, Walter Ling -- Hallucinogens and club drugs -- Neurobiology of hallucinogens / Richard A. Glennon -- Hallucinogens and club drugs / Michael F. Weaver, Sidney H. Schnoll -- Other substances -- Nicotine and tobacco / Tony P. George, Andrea H. Weinberger -- Benzodiazepines and other sedatives and hypnotics / Adam Bisaga -- Treatment of anabolic-androgenic steroid-related disorders / Harrison G. Pope, Jr., Kirk J. Brower -- Opioids -- Neurobiology of opiates and opioids / Mary Jeanne Kreek -- Detoxification of opioids / Soteri Polydorou, Herbert D. Kleber -- Opioid maintenance treatment / Richard S. Schottenfeld -- Buprenorphine maintenance / Eric C. Strain, Michelle R. Lofwall -- Antagonists of opioids / Charles O'Brien, Kyle M. Kampman -- Part 4 : Treatment modalities -- Psychodynamics / Hallie A. Lightdale, Avram H. Mack, Richard J. Frances -- Cognitive-behavioral therapies / Kathleen M. Carroll -- Motivational enhancement / Carlo C. DiClemente, Miranda Garay, Leigh Gemmell -- Twelve-step facilitation / Richard K. Ries, Marc Galanter, J. Scott Tonigan -- Contingency management / Stephen T. Higgins, Kenneth Silverman -- Network therapy / Marc Galanter -- Group therapy / David W. Brook -- Family therapy / Timothy J. O'Farrell, William Fals-Stewart -- Part 5 : Rehabilitation settings -- Inpatient treatment / Roger D. Weiss, Jennifer Sharpe Potter, Rocco A. Iannucci -- Therapeutic communities / George De Leon -- Community-based treatment / Jonathan I. Ritvo, Harvey L. Causey III -- Alcoholics anonymous and other 12-step programs -- Psychological mechanisms in alcoholics anonymous / J. Scott Tonigan, Gerard J. Connors -- The history of alcoholics anonymous and the experiences of patients / Edgar P. Nace -- Outcome research on 12-step and other self-help programs / Rudolf H. Moos, Christine Timko -- Part 6 : Special populations -- Adolescent substance abuse / Yifrah Kaminer -- The mentally ill substance abuser / Stephen Ross -- Women and addiction / Kathleen T. Brady, Sudie E. Back -- Perinatal substance abuse / Loretta P. Finnegan, Stephen R. Kandall -- HIV/AIDS and hepatitis C / Steven L. Batki, Kalpana I. Nathan -- Prescription drug abuse / Wilson M. Compton, Richard Denisco -- Substance use disorders among physicians / J. Wesley Boyd, John R. Knight -- Gay men and lesbians / Robert Paul Cabaj -- Minorities / Joseph Westermeyer, Daniel Dickerson -- Part 7 : Special topics -- Testing to identify recent drug use / Robert L. DuPont, Carl M. Selavka -- Medical education / Erik W. Gunderson, Frances R. Levin, Petros Levounis -- Prevention of substance abuse / Richard R. Clayton, Melissa J.H. Segress, Crystal A. Caudill -- Forensic addiction psychiatry / Avram H. Mack, Monica Barros.
  • 1916-From: Google Books
    by Leonard Metcalf and Harrison P. Eddy.
    I. Design of sewers -- II. Construction of sewers -- III. Disposal of sewage.
    Also available: Print – 1916-
  • Elisabeth Rosenthal.
    "An award-winning New York Times reporter Dr. Elisabeth Rosenthal reveals the dangerous, expensive, and dysfunctional American healthcare system, and tells us exactly what we can do to solve its myriad of problems. It is well documented that our healthcare system has grave problems, but how, in only a matter of decades, did things get this bad? Dr. Elisabeth Rosenthal doesn't just explain the symptoms; she diagnoses and treats the disease itself. Rosenthal spells out in clear and practical terms exactly how to decode medical doublespeak, avoid the pitfalls of the pharmaceuticals racket, and get the care you and your family deserve. She takes you inside the doctor-patient relationship, explaining step by step the workings of a profession sorely lacking transparency. This is about what we can do, as individual patients, both to navigate a byzantine system and also to demand far-reaching reform. Breaking down the monolithic business into its individual industries--the hospitals, doctors, insurance companies, drug manufacturers--that together constitute our healthcare system, Rosenthal tells the story of the history of American medicine as never before. The situation is far worse than we think, and it has become like that much more recently than we realize. Hospitals, which are managed by business executives, behave like predatory lenders, hounding patients and seizing their homes. Research charities are in bed with big pharmaceutical companies, which surreptitiously profit from the donations made by working people. Americans are dying from routine medical conditions when affordable and straightforward solutions exist. Dr. Rosenthal explains for the first time how various social and financial incentives have encouraged a disastrous and immoral system to spring uporganicallyin a shockingly short span of time. The system is in tatters, but we can fight back. An American Sicknessis the frontline defense against a healthcare system that no longer has our well-being at heart"-- Provided by publisher.
  • 2012From: Springer Protocols
    edited by Michail A. Alterman, Peter Hunziker.
    Rapid LC-MS/MS profiling of protein amino acids and metabolically related compounds for large-scale assessment of metabolic phenotypes -- Combination of an AccQ. Tag-ultra performance liquid chromatographic method with tandem mass spectrometry for the analysis of amino acids -- Isotope dilution liquid chromatography-tandem mass spectrometry for quantitative amino acid analysis -- Analysis of underivatized amino acids: Zwitterionic hydrophilic interaction chromatography combined with triple quadrupole tandem mass spectrometry -- Amino acid analysis via LC-MS method after derivatization with quaternary phosphonium -- Amino acid analysis by hydrophilic interaction chromatography coupled with isotope dilution mass spectrometry -- A universal HPLC-MS method to determine the stereochemistry of common and unusual amino acids -- Amino acid analysis by capillary electrophoresis-mass spectrometry -- New advances in amino acid profiling by capillary electrophoresis-electrospray ionization-mass spectrometry -- Optimal conditions for the direct RP-HPLC determination of underivatized amino acids with online multiple detection -- Absolute quantitation of proteins by acid hydrolysis combined with amino acid detection by mass spectrometry -- Amino acid analysis by means of MALDI TOF mass spectrometry or MALDI TOF/TOF tandem mass spectrometry -- Heptafluorobutyl chloroformate-based sample preparation protocol for chiral and nonchiral amino acid analysis by gas chromatography -- The EZ:Faast family of amino acid analysis kits: Application of the GC-FID kit for rapid determination of plasma tryptophan and other amino acids -- Amino acid analysis in physiological samples by GC-MS with propyl chloroformate derivatization and iTRAQ-LC-MS/MS -- Automated analysis of primary amino acids in plasma by high-performance liquid chromatography -- RP-LC of phenylthiocarbamyl amino acid adducts in plasma acetonitrile extracts: Use of multiple internal standards and variable wavelength UV detection -- Quantification of underivatised amino acids on dry blood spot, plasma, and urine by HPLC-ESI-MS/MS -- Capillary electrophoresis of free amino acids in physiological fluids without derivatization employing direct or indirect absorbance detection -- Measurement of 3-nitro-tyrosine in human plasma and urine by gas chromatography-tandem mass spectrometry -- Analysis of hydroxyproline in collagen hydrolysates -- Innovative and rapid procedure for 4-hydroxyproline determination in meat-based foods -- Multiple reaction monitoring for the accurate quantification of amino acids: Using hydroxyproline to estimate collagen content -- Sequential injection chromatography for fluorimetric determination of intracellular amino acids in marine microalgae -- Direct analysis of underivatized amino acids in plant extracts by LC-MS-MS -- Wheat gluten amino acid analysis by high-performance anion-exchange chromatography with integrated pulsed amperometric detection -- Preparative HPLC separation of underivatized amino acids for isotopic analysis -- Quantification of amino acids in a single cell by microchip electrophoresis with chemiluminescence detection.
  • 2007From: Springer
    volume editor, Volker F. Wendisch.
  • 2012From: CRCnetBASE
    H. DeWayne Ashmead.
    Ch. 1. The fundamentals of mineral nutrition -- ch. 2. The chemistry of chelation -- ch. 3. The history of nutritional chelates -- ch. 4. The requirements for a nutritionally functional chelate -- ch. 5. The development of analytical methods to prove amino acid chelation -- ch. 6. Absorption of amino acid chelates from the alimentary canal -- ch. 7. The pathways for absorption of an amino acid chelate -- ch. 8. The absorption of amino acid chelates by active transport -- ch. 9. The absorption of amino acid chelates by facilitated diffusion -- ch. 10. The fate of amino acid chelates in the mucosal cell -- ch. 11. The uptake of amino acid chelates into and out of the plasma -- ch. 12. Tissue metabolism of amino acid chelates -- ch. 13. Some metabolic responses of the body to amino acid chelates -- ch. 14. Toxicity of amino acid chelates -- ch. 15. The absorption and metabolism of amino acid chelates.
  • 2013From: CRCnetBASE
    Guoyao Wu.
    This up-to-date book presents basic concepts and recent advances in amino acid biochemistry and nutrition, providing comprehensive coverage of developments over the past 45 years. It includes information on absorption, metabolism, and excretion of amino acids while addressing protein quality and requirements. The text discusses metabolic pathways of amino acids in relation to health and disease in various organisms, as well as species differences in metabolism of amino acids. The author also presents a critical analysis of amino acid supplementation to humans and animals.
  • 2008From: CRCnetBASE
    Mauro Di Pasquale.
  • edited by Roger W. Jeanloz and Endre A. Balazs.
    PrintStatus: Not Checked OutLane Catalog Record
    v. 1A. Jeanloz, Roger W., ed. Chemistry of amino acids -- v. 2A. Distribution and biological role -- v. 2B. Metabolism and interactions.
  • 2012From: ScienceDirect
    2012From: ClinicalKey
    [edited by] Michael J. Aminoff ; with 49 contributing authors.
    The emergence of electrophysiology as an aid to neurology / Mary A.B. Brazier -- Electrophysiologic equipment and electrcial safety / John A. Cadwell and Richard A. Villarreal -- Electroencephalography and magnetoencephalography. Electroencephalography: general principles and clinical applications / Michael J. Aminoff -- Neonatal and pediatric electroencephalography / Jin S. Hahn -- Electroencephalographic artifacts and benign variants / Jeffrey W. Britton -- Video-EEG monitoring for epilepsy / John M. Stern and Jerome Engel, Jr. -- Invasive clinical neurophysiology in epilepsy and movement disorders / William J. Marks, Jr and Kenneth D. Laxer -- Topographic mapping, frequency analysis, and other quantitative techniques in electroencephalography / Marc R. Nuwer and Pedro Coutin-Churchman -- Intraoperative electroencephalographic monitoring during carotid endarterectomy and cardiac surgery / Gregory D. Cascino and Frank W. Sharbrough, III -- Magnetoencephalography / William W. Sutherling -- Electromyography, nerve conduction studies, and related techniques. Clinical electromyography / Michael J. Aminoff -- Quantitative electromyography / Mark B. Bromberg -- Nerve conduction studies / Jasper R. Daube and Devon I. Rubin -- Microneurography and its potential clinical applications / David Burke -- Nerve excitability: a clinical translation / Matthew C. Kiernan and Cindy Shin Yi Lin -- Neuromuscular ultrasound as a complement to the electrodiagnostic evaluation / Francis O. Walker and Michael S. Cartwright -- Electrophysiologic study of disorders of neuuromuscular transmission / Donald B. Sanders -- H-reflex and F-response studies / Morris A. Fisher -- The blink reflex and other cranial nerve reflexes / Josep Valls-Sole -- Electrophysiologic evaluation of movement disorders / Mark Hallett -- Evaluation of the autonomic nervous system / Michael J. Aminoff -- Evoked potentials and related techniques. Visual evoked potentials, electroretinography, and other diagnostic approaches to the visual system / Ari J. Green -- Visual evoked potentials in infants and children / Eileen E. Birch and Vidhya Subramanian -- Brainstem auditory evoked potentials: methodology, interpretation, and clinical application / Alan D. Legatt -- Brainstem auditory evoked potentials in infants and children / Terence W. Picton, margot J. Taylor, and Andree Durieux-Smith -- Somatosensory evoked potentials / Michael J. Aminoff and Andrew Eisen -- Somatosensory evoked potentials in infants and children / Michael J. Aminoff -- Diagnostic and therapeutic role of magnetic stimulation in neurologuy / Robert Chen and Nicolae Petrescu -- Event-related potentials / Douglas S. Goodin -- Intraoperative monitoring by evoked potential techniques / Ronald G. Emerson and David C. Adams -- Bladder, bowel, and sexual dysfunction. electrophysiologic evaluation of sacral function / Simon Podnar and David B. Vodusek -- Tests of vestibular function. Vestibular laboratory testing / Joseph M. Furman and Floris L. Wuyts -- Electrophysiologic evaluation in special situations. Polysomnographic evaluation fo sleep disroders / Vivien C. Abad and Christian Guilleminault -- Electrophysiologic evaluation of patients in the intensive care unit / G. Bryan Young and Charles F. Bolton -- Electrophysiologic evaluation of brain death: a critical appraisal / Thomas P. Bleck -- Electrophysiologic techniques in the evaluation of patients with suspected neurotoxic disorders / Michael J. Aminoff and James W. Albers.
  • 2014From: ClinicalKey
    [edited by] Michael J. Aminoff, S. Andrew Josephson.
    Aminoff's Neurology and General Medicine is the standard and classic reference providing comprehensive coverage of the relationship between neurological practice and general medicine. As neurologists are asked to consult on general medical conditions, this reference provides an authoritative tool linking general medical conditions to specific neurological issues and disorders. This is also a valuable tool for the general practitioner seeking to understand the neurological aspects of their medical practice. Completely revised with new chapters covering metastatic disease, bladder disease, psychogenic disorders, dementia, and pre-operative and post-operative care of patients with neurologic disorders, this new edition will again be the go-to reference for both neurologists and general practitioners.
  • 2016From: Springer
    Mario D. Cordero, Benoit Viollet, editors.
    Part I: AMPK in health -- Structure and Regulation of AMPK -- AMPK Regulation of Carbohydrate Metabolism -- AMPK Regulation of Lipid Metabolism -- AMPK Regulation of Protein Metabolism -- AMPK Regulation of cell growth, apoptosis, autophagy and bioenergetics -- AMPK Regulation of immunology -- AMPK and Stem Cells -- Part II: AMPK in the diseases -- AMPK in metabolic diseases -- AMPK in neurodegenerative diseases -- AMPK in cardiovascular diseases -- AMPK in cancer -- AMPK in aging -- AMPK in musculoskeletal diseases and pain -- AMPK in pathogens -- Part III: Pharmacology of AMPK -- Metformin, new drugs and AMPK -- Small molecules and AMPK -- Nutraceutical compounds and AMPK -- Part IV: Methods of study in AMPK -- Animal models -- In vitro study methods.
  • 2010From: Springer
    edited by Craig Murray.
  • PrintStatus: Not Checked OutLane Catalog Record
  • 2016From: Springer
    Vincent Di Marino, Yves Etienne, Maurice Niddam.
    Preface -- Foreword -- History of the amygdala -- Formation of the amygdala -- Amygdala and Limbic system -- Functions of the amygdala -- Dissection of the amygdala -- Morphology of the amygdala -- Connections of the amygdala -- Projections from and toward amygdala -- The relationships of the amygdala -- The BST (bed nucleus of the stria terminalis) -- The extended amygdala -- Vascularization of the amygdala -- Consequences of the ablation -- Conclusions and prospects -- Bibliography -- Index.
  • 2015From: Springer
    Maria M. Picken, Ahmet Dogan, Guillermo A. Herrera, editors.
  • 2012From: Springer
    Maria M. Picken, Ahmet Dogan, Guillermo A. Herrera, editors.
    Abnormal proteins are known to be associated with various pathologies. Most notably, these include amyloidoses, monoclonal protein deposits associated with plasma cell dyscrasia/multiple myeloma, cryoglobulins and various related organized and non-organized deposits. Amyloid and Related Disorders presents an overview of the most recent developments in this area including clinical presentation, etiology, pathogenesis, and differential diagnosis. The rationale for various therapies, including transplantation, is discussed and tissue diagnosis (its pitfalls and strategies for avoiding them) and laboratory support are included. The involvement of all major organ systems including renal/genitourinary, cardiac, gastrointestinal, pulmonary, peripheral nerve/central nervous system, soft tissue and bone marrow pathology is covered. This approach provides a unifying concept of these pathologic processes, which have systemic involvement, and which have, hitherto, not been universally appreciated. Awareness of these diseases among a wider audience of pathologists may increase the rate of their diagnosis as well as that of earlier diagnosis. This volume will be invaluable to specialized and general pathologists as well as cytopathologists; other medical professionals may also benefit from this concise update on the systemic amyloidoses.
  • Adrienne Orr.
    Alzheimer's disease (AD) is a progressive neurodegenerative disorder affecting the elderly that is characterized by loss of short-term memory and cognitive decline. Studies in both human patients and animal models of AD point to over-accumulation of soluble oligomers of amyloid-beta peptide (Abeta) as a mediator of learning and memory impairments early in the disease (Rowan, Klyubin et al. 2005; Selkoe 2008). Support for Abeta's role in learning deficits comes from studies demonstrating impaired plasticity of synaptic inputs to neurons, as measured in the paradigm of long-term potentiation (LTP) of synaptic strength in hippocampal slices (Chen, Kagan et al. 2000; Freir, Holscher et al. 2001; Walsh, Klyubin et al. 2002; Wang, Pasternak et al. 2002; Townsend, Shankar et al. 2006), the prime candidate for the neuronal substrate of learning and memory behavior (Bliss and Collingridge 1993). Induced concurrently with synaptic LTP is an increase in the electrical coupling between the dendritic synaptic inputs and the soma, such that a greater proportion of the EPSP survives at the spike trigger zone, resulting in greater action potential output for a given EPSP. This potentiation of EPSP-spike coupling (E-S coupling) provides an additional boost to the efficacy of the EPSP on top of the potentiation (LTP) that occurs at the synapse (Bliss and Lomo 1973). While LTP of synaptic strength is an essential component of memory storage, in all models of learning, memory recall occurs only when spikes are evoked in the neurons participating in a representation. Thus E-S potentiation exerts control over the essential substrate of memory retrieval. Although LTP and E-S potentiation are mechanistically distinct processes, several features during the induction phase are shared. Studies have shown that Abeta impairs the induction, but not maintenance of LTP (Wang, Walsh et al. 2004; Townsend, Shankar et al. 2006), leaving the possibility that Abeta-mediated impairment to memory is not specific to LTP. Nevertheless, focus has centered on pathways central to LTP, while impairment to other forms of plasticity have not been explored. Here we show a mechanism by which Abeta peptides impairs post-tetanic suppression of inhibition, thereby inhibiting E-S potentiation. This impairment to E-S potentiation was occluded by GABAA-receptor, Cannabinoid 1 receptor (CB1R), and muscarinic acetylcholine receptor (mAChR), but not mGluR block. This suggests that the impairment is mediated by mAChR-initiated endocannbinoid signaling. Together, the results provide a mechanism to explain learning and memory impairments in early Alzheimer's disease.
  • 2012From: Springer Protocols
    edited by Einar M. Sigurdsson, Miguel Calero, María Gasset.
    Rapid generation of dityrosine cross-linked A-[beta] oligomers via cu-redox cycling / Adam P. Gunn, Blaine R. Roberts, and Ashley I. Bush -- Application of photochemical cross-linking to the study of oligomerization of amyloidogenic proteins / Dahabada H.J. Lopes [and others] -- Preparation of stable amyloid b-protein oligomers of defined assembly order / Clark Rosensweig [and others] -- Purification and fibrillation of full-length recombinant PrP / Natallia Makarava and Ilia V. Baskakov -- Featuring amyloids with fourier transform infrared and circular dichroism spectroscopies / Miguel Calero and María Gasset -- Quasielastic light scattering study of amyloid b-protein fibrillogenesis / Aleksey Lomakin and David B. Teplow -- Conformations of microtubule-associated protein tau mapped by fluorescence resonance energy transfer / Sadasivam Jeganathan [and others] -- Measuring the kinetics of amyloid fibril elongation using quartz crystal microbalances / Alexander K. Buell, Christopher M. Dobson, and Mark E. Welland -- X-ray fibre diffraction studies of amyloid fibrils / Kyle L. Morris and Louise C. Serpell -- Structural characterization of prefibrillar intermediates and amyloid fibrils by small-angle x-ray scattering / Annette Eva Langkilde and Bente Vestergaard -- Atomic force fluorescence microscopy in the characterization of amyloid fibril assembly and oligomeric intermediates / Valeriy Ostapchenko, Maria Gasset, and Ilia V. Baskakov -- Investigating fibrillar aggregates of tau protein by atomic force microscopy / Susanne Wegmann, Daniel J. Muller, and Eckhard Mandelkow -- Structural studies of amyloids by quenched hydrogen-deuterium exchange by NMR / Marçal Vilar, Lei Wang, and Roland Riek -- Cyclic amplification of prion protein misfolding / Marcelo A. Barria, Dennisse Gonzalez-Romero, and Claudio Soto -- Search for amyloid-binding proteins by affinity chromatography / Miguel Calero, Agueda Rostagno, and Jorge Ghiso -- Establishing the links between A[beta] aggregation and cytotoxicity in vitro using biophysical approaches / Asad Jan and Hilal A. Lashuel -- Preparation of cultured human vascular cells / Ingvar H. Olafsson, Dadi Th. Vilhjalmsson, and Finnbogi R. Thormodsson -- Murine cerebrovascular cells as a cell culture model for cerebral amyloid angiopathy : isolation of smooth muscle and endothelial cells from mouse brain / Sebastien A. Gauthier [and others] -- In vitro assays measuring protection by proteins such as cystatin C of primary cortical neuronal and smooth muscle cells / Sebastien A. Gauthier [and others] -- Study of neurotoxic intracellular calcium signalling triggered by amyloids / Carlos Villalobos [and others] -- Bacterial amyloids / Yizhou Zhou [and others] -- Study of amyloids using yeast / Reed B. Wickner [and others] -- Cell-to-cell transmission of [alpha]-synuclein aggregates / Seung-Jae Lee [and others] -- Subcutaneous adipose tissue biopsy for amyloid protein studies / Per Westermark -- Analysis of s100 oligomers and amyloids / Hugo M. Botelho, Günter Fritz, and Cláudio M. Gomes -- S100A8/A9 amyloidosis in the ageing prostate : relating ex vivo and in vitro studies / Anna L. Gharibyan, Dina Raveh, and Ludmilla A. Morozova-Roche -- Isolation of amyloid by solubilization in water / Dadi Th. Vilhjalmsson, Indiana E. Ingolfsdottir, and Finnbogi R. Thormodsson -- Histological staining of amyloid and pre-amyloid peptides and proteins in mouse tissue / Hameetha B. Rajamohamedsait and Einar M. Sigurdsson -- Pentameric luminescent-conjugated oligothiophene for optical imaging of in vitro-formed amyloid fibrils and protein aggregates in tissue sections / K. Peter R. Nilsson, Mikael Lindgren, and Per Hammarström -- In vivo magnetic resonance imaging of amyloid-[beta] plaques in mice / Youssef Zaim Wadghiri [and others] -- Mouse model for scrapie : inoculation, clinical scoring, and histopathological techniques / Michele A. Di Bari, Romolo Nonno, and Umberto Agrimi -- Biochemical isolation of insoluble tau in transgenic mouse models of tauopathies / Carl Julien, Alexis Bretteville, and Emmanuel Planel -- Tissue processing prior to analysis of alzheimer's disease associated proteins and metabolites, including A[beta] / Stephen D. Schmidt, Ralph A. Nixon, and Paul M. Mathews -- A-[beta] measurement by enzyme-linked immunosorbent assay / Stephen D. Schmidt [and others] -- Cognitive and sensorimotor tasks for assessing functional impairments in mouse models of Alzheimer's Disease and related disorders / Allal Boutajangout [and others].
  • 2010From: Springer
    edited by Morie A. Gertz, S. Vincent Rajkumar.
    Fibril structure and fibrillogenesis -- Imaging of systemic amyloidosis -- Diagnosis and classification -- Pathogenesis of systemic amyloidoses -- Supportive care for amyloidosis -- Assessing response and prognosis in AL amyloidosis -- Localized amyloidosis -- Amyloid heart disease -- Renal amyloidosis -- Primary systemic amyloid neuropathy -- Conventional treatment of amyloidosis -- High-dose therapy in amyloidosis -- Secondary, AA, amyloidosis -- ATTR: diagnosis, prognosis, and treatment -- Other systemic forms of amyloidosis.
  • hazırlayan Abdullah Kılıç ; danışmanlar/consultants Ayten Altintas ... [and others] ; ... çeviri ve redaksiyon/translation Zeynep Alp ve Ekibi ...
    PrintStatus: Not Checked OutLane Catalog Record
    Discusses "houses of healing" established during the Seljuk and Ottoman eras which were visited by the authors. Evaluates these charitable institutions from the perspective of the history of medicine, the history of art, and cultural history. Presents medicine as practiced in the Anatolian Seljuk and Ottoman Empires, was well as their hospitals, followed by coverage of each facility (about 20, of which only two continue as hospitals).
  • 2013From: ClinicalKey
    Steve M. Yentis, Nicholas P. Hirsch, James K. Ip ; original contributions by Gary B. Smith.
    Building on the success of previous editions, Anaesthesia and Intensive Care A-Z (Fifth edition) remains the most comprehensive single volume source of relevant aspects of pharmacology, physiology, anatomy, physics, statistics, medicine, surgery, general anaesthetic practice, intensive care, equipment, and the history of anaesthesia and intensive care. Originally prepared as essential reading for candidates for the Fellowship of the Royal College of Anaesthetists and similar exams, this fully updated edition will also prove as invaluable as ever for all anaesthetists and critical care phys.
  • Keith Sykes ; with John Bunker, contributing editor.
    PrintStatus: Not Checked OutLane Catalog Record
  • 2009From: Springer
    Marinella Astuto, editor.
  • 2007From: Springer
    A. Gullo (editor).
  • 2008From: Springer
    A. Gullo, (editor).
    Advances on critical care -- Airway -- Trauma -- Obstetrics -- Paediatric anaesthesia -- Cardiac arrest -- Infections, sepsis, organ dysfunction -- Perioperative care -- Quality of care in the ICU.
  • 2014From: Springer
    edited by Antonino Gullo.
    The APICE 2013 yearbook examines recent advances in various aspects of critical care medicine and highlights the importance of effective communication among researchers, scientists, and clinicians. Among the many topics addressed are trauma care organization, the management of patients with cardiovascular, kidney, and lung disorders, issues relating to severe infections and sepsis, and the humanization of end of life care. The overriding goal of the book is to provide guidance and stimulate further thought on how professional performance in critical care medicine can be improved. Triple B translational research, from the bench to the bedside and back again (via the translation of clinical observations into new research questions), will play a major role in this context, and is particularly discussed in the chapter about sepsis and organ dysfunction. There is no doubt that the transfer of far-reaching and dynamic developments in molecular and cellular biology into clinical practice will be a key component in delivering the care required by individual patients.
  • 2011From: Springer
    Antonino Gullo (ed.).
    pt. I. Continuing medical education -- 1. Can I Think what I Read? / Philip D. Lumb -- pt. II. Clinical pharmacology -- 2. Pharmacological Manipulation in ICU / Daniel De Backer, Katia Donadello and Sabino Scolletta -- pt. III. Kidney -- 3. Renal Injury / Vladimir Gašparović, Ivan Gornik -- pt. IV. Ventilation: adult and paediatric -- 4. Respiratory Mechanics: Principles, Utility and Advances / Alysson R. Carvalho, Walter A. Zin -- 5. Capnometry/capnography in Prehospital Cardiopulmonary Resuscitation / Štefek Grmec, Katia Lah and Štefan Mally -- 6. Weaning from Mechanical Ventilation / Irene Cortés Puch, Andrés Esteban -- 7. Ventilatory Strategies in Acute Lung Injury / Edoardo Calderini, Sara Sher and Eleonora Allegritti -- 8. Mechanical Ventilation Beyond the PICU / Giancarlo Ottonello, Alessia Franceschi -- pt. V. Cardiovascular monitoring 9. The Nexfin Monitor--A Totally Non-Invasive Cardiac Output Monitor / Azriel Perel, Wilbert Wesselink and Jos Settels -- 10. Doppler Echocardiography in ICU Patients: Does It Improve Outcome? / Jan Poelaert -- pt. VI. Management of cardiac arrest -- 11. Mild Therapeutic Hypothermia after Cardiac Arrest / Tommaso Pellis, Vincenzo Mione and Willy P. Mercante -- 12. Nasopharyngeal Cooling During Cardiopulmonary Resuscitation / Francesco Fumagalli, Giuseppe Ristagno -- 13. Amplitude Spectrum Area as a Predictor of Successful Defibrillation / Giuseppe Ristagno, Yongqin Li, Antonino Gullo and Joe Bisera -- pt. VII. Advances in experimental and clinical research -- 14. Physiopathology and Severity of Post-Resuscitation Myocardial Dysfunction: Effects of Sodium-Hydrogen Exchanger Isoform-1 (NHE-1) Inhibitors and Erythropoietin / Raúl J. Gazmuri, Iyad M. Ayoub and Jeejabai Radhakrishnan -- 15. Experimental Treatment for Preservation of Mechanically Competent Cardiac Activity Following Cardiac Arrest / Iyad M. Ayoub, Jeejabai Radhakrishnan and Raúl J. Gazmuri -- 16. Erythropoietin Facilitates Return of Spontaneous Circulation and Survival in Victims of Out-of-Hospital Cardiac Arrest / Štefek Grmec, Matej Strand and Raúl J. Gazmuri -- pt. VIII. Infections, sepsis and organ dysfunctions -- 17. Pathophysiology of Resistance amongst Aerobic Gram-negative Bacilli in Particular Acinetobacter Species / Nia Taylor, Luciano Silvestri and Hendrick K.F. Van Saene -- 18. What Have We Learned from the Surviving Sepsis Campaign? / Jean-Louis Vincent, Katia Donadello and Leonardo Gottin -- 19. Source Control / Gabriele Sganga, Valerio Cozza -- 20. Immunoglobulins in Sepsis / Giorgio Berlot, Claudio M. Vassallo and Nicola Busetto -- pt. IX. Perioperative medicine -- 22. Perioperative Medicine--An Introduction / Antonino Gullo, Chiara M. Celestre, Annalaura Paratore and Fortunato Stimoli -- 23. Neuraxial Analgesia for Caesarean and Vaginal Delivery and Childhood Learning Disabilities / Juraj Sprung, Randall Flick and David Warner -- 24. Off-label Drugs in Perioperative Medicine: Clonidine / Cesare Gregoretti, Paolo Pelosi -- pt. X. Spinal cord stimulation -- 25. Cost Effectiveness of Spinal Cord Stimulation in the Management of Severe Angina / Mats Börjesson, Clas Mannheimer -- pt. XI. Neurotrauma -- 26. Clinical Assessment and Diagnostic Procedures in Neurotrauma / Marco Zanello, Matteo Vincenzi and Marco Bandini -- pt. XII. Disaster medicine -- 27. Disaster Preparedness / Francesco Della Corte, Pier Luigi Ingrassia -- 28. Medical Emergency Response in Toxicological Mass Casualty / Pier Luigi Ingrassia, Luca Ragazzoni and Francesco Della Corte -- pt. XIII. Quality of care -- 29. Telemedicine to Improve Care in the Critically Ill / Gastón Murias, Bernat Sales Lluis Blanch -- 30. Professionalism, Quality of Care and Pay-for-Performance Services / Antonino Gullo, Cristina Santonocito, Paolo Murabito and Marinella Astuto.
  • 2012From: Springer
    Eli D. Ehrenpreis, Shmuel Avital, Marc Singer, editors.
    Anal and Rectal Diseases: A Concise Manual provides a succinct reference on the subject for clinicians, including primary care physicians, gastroenterologists, general surgeons, physician's assistants and nurse practitioners. Presented in a consistent structural style that provides both a general summary of individual topics within the field along with additional details to assist those with some background knowledge in the subject area, this handy volume provides information related to the field of anorectal disease in a format that is easily accessible for rapid acquisition of knowledge. Each topic is outlined in a multidisciplinary fashion with the medical, surgical, and pathological aspects clearly detailed in each section. Each section clearly describes the condition with up-to-date management guidelines and precious clinical pearls. The volume features high quality illustrations in the form of elegant hand drawn figures, tables, photographs of physical findings, endoscopic finds and radiographs. The clinical photographs and x-rays will be of great value to gastroenterologists whose specialty is not coloproctology. Chapters on computerized tomographic colography (virtual colonoscopy) and others cover the newer technologies employed for diagnostic purposes in these diseases. Anal and Rectal Diseases: A Concise Manual provides clinicians with a tool for rapid consultation for direct patient care and management.
  • 2014From: Springer
    Herand Abcarian, editor.
    1. Epidemiology, Incidence and Prevalence of Fistula in Ano / Richard L. Nelson and Herand Abcarian -- 2. Applied Anatomy / Russell K. Pearl -- 3. Relationship of Abscess to Fistula / Hernand Abcarian -- 4. Classification and Treatment of Anorectal Infections / Adrian E. Ortega and Kyle G. Cologne -- 5. Clinical Assessment of Anal Fistulas / Herand Abcarian -- 6. Clinical Assessment and Imaging Modalities of Fistula in Ano / Kyle G. Cologne, Juan Antonio Villanueva-Herrero, Enrique Montaño-Torres, and Adrian E. Ortega -- 7. Classification and Management Strategies / Herand Abcarian -- 8. Seton (Loose, Cutting, Chemical) / Varnsi R. Velchuru -- 9. Fistulotomy and Lay Open Technique / Philip Tozer and Robin K.S. Phillips -- 10. Fistulectomy with Primary Sphincter Reconstruction / Alexander Herold -- 11. Fibrin Sealant / Jose R. Cintron -- 12. Biologic Fistula Plugs / Samuel Eisenstein and Alex Jenny Ky -- 13. Synthetic Fistula Plug / Alex Jenny Ky, Michael Polcino, and Alero T. Nanna -- 14. Endorectal Advancement Flap / Christine C. Jensen -- 15. Dermal Advancement Flap / Christine C. Jensen -- 16. Ligation of Intersphincteric Fistula Tract (LIFT) / Ariane M. Abcarian -- 17. Video-Assisted Anal Fistula Teatment (VAAFT) / Piercarlo Meinero and Lorenzo Mori -- 18. Stem Cell Application in Fistula Disease / Damian Garcia-Olmo and Hector Guadalajara-Labajo -- 19. Crohn's Disease / James Fleshman and Rachel Tay -- 20. Tuberculosis Fistula / Pravin Jaiprakash Gupta -- 21. Fistula Surgery in the Era of Evidence-Based Medicine / Richard L. Nelson and Hernand Abcarian -- 22. Causes of Operative Failure / Mohammad Ali Abbass and Maher Aref Abbas 23. Recurrence/Persistence After Fistula Teatmcnt: What Next? / Hernand Abcarian.
  • 2007From: Springer
    contributors, F. Benedetti ... [et al.] ; editor, Christoph Stein.
    Part I. Introduction -- Peripheral and central mechanism of pain generation / H.G. Schaible -- Part II. Drugs in clinical use -- Opioids / C. Zöllner, C. Stein -- Antipyretic analgesics: nonsteroidal antiinflammatory drugs, selective COX-2 inhibitors, paracetamol and pyrazolionones / B. Hinz, K. Brune -- Local anesthetics / R. Yanagidate, G.R. Strichartz -- Serotonin receptor ligands: treatments of acute migraine and cluster headache / P.J. Goadsby -- Anti-convulsants and anti-depressants / A.H. Dickenson, J. Ghandehari -- Part III. Compounds in preclinical development -- Neuropeptide and kinin antagonists / R. G. Hill, K.R. Oliver -- Glutamate receptor ligands / V. Neugebauer -- Adrenergic and cholinergic compounds / R. D. Sanders, M. Maze -- Cannabinoids and pain / I.J. Lever, A.S.C. Rice -- Part IV. Future targets in analgesia research -- Adenosine and ATP receptors / J. Sawynok -- Ion channels in analgesia research / J.N. Wood -- Protein kinases as potential targets for the treatment of pathological pain / R. R. Ji, Y. Kawasaki, Z. Y. Zhuang, Y.R. Wen, Y.Q. Zhang -- Part V. Pain Management beyond pharmacotherapy -- Placebo and endogenous mechanisms of analgesia / F. Bededetti -- Limitations of pharmacotherapy: behavioral approaches to chronic pain / H. Flor, M. Diers -- Subject index.
  • 2013From: Cambridge
    Steve Jentis, Surbhi Malhotra.
    Part I. Preconception and Conception -- Part II. Pregnancy -- Part III. Puerperium and After -- Part IV. Organisational Aspects.
  • 2012From: Future Med
    editors, Frank Porecca, Tamara King.
    Analgesics for cancer pain / Tamara King & Frank Porreca -- Cancer pain assessment and consensus guidelines / Brian Wilhelmi & Paul J. Christo -- Role of step 2 opioid analgesics in mild-to-moderate pain intensity treatment / Wojciech Leppert -- Opioid analgesics for severe cancer pain / Phillip Good & Janet Hardy -- Alternative opioids and administration routes / Mellar P. Davis -- Adjuvant analgesics for cancer pain / Russell K. Portenoy & Ebtesam Ahmed -- Analgesics for breakthrough pain / Sebastiano Mercadante -- Emerging analgesics and future directions : targeting bone remodeling / Flaminia Coluzzi -- Emerging analgesics and future directions : targeting neuroplasticity / Alysia N. Lozano-Ondoua & Todd W. Vanderah -- Index.
  • 2013From: Wiley
    edited by János Fischer, C. Robin Ganellin, David P. Rotella.
    General Aspects. Pioneer and Analogue Drugs / Janos Fischer, C Robin Ganellin, David P Rotella -- Competition in the Pharmaceutical Drug Development / Christian Tyrchan, Fabrizio Giordanetto -- Metabolic Stability and Analogue-Based Drug Discovery / Amit S Kalgutkar, Antonia F Stepan -- Use of Macrocycles in Drug Design Exemplified with Ulimorelin, a Potential Ghrelin Agonist for Gastrointestinal Motility Disorders / Mark L Peterson, Hamid Hoveyda, Graeme Fraser, Eric Marsault, Rene Gagnon -- Drug Classes. The Discovery of Anticancer Drugs Targeting Epigenetic Enzymes / A Ganesan -- Thienopyridyl and Direct-Acting P2Y Receptor Antagonist Antiplatelet Drugs / Joseph A Jakubowski, Atsuhiro Sugidachi -- Selective Estrogen Receptor Modulators / Amarjit Luniwal, Rachael Jetson, Paul Erhardt -- Discovery of Nonpeptide Vasopressin V2 Receptor Antagonists / Kazumi Kondo, Hidenori Ogawa -- The Development of Cysteinyl Leukotriene Receptor Antagonists / Peter R Bernstein -- Case Studies. The Discovery of Dabigatran Etexilate / Norbert Hauel, Andreas Clemens, Herbert Nar, Henning Priepke, Joanne van Ryn, Wolfgang Wienen -- The Discovery of Citalopram and Its Refinement to Escitalopram / Klaus P Bogeso, Connie Sanchez -- Tapentadol : From Morphine and Tramadol to the Discovery of Tapentadol / Helmut Buschmann -- Novel Taxanes: Cabazitaxel Case Study / Herve Bouchard, Dorothee Semiond, Marie-Laure Risse, Patricia Vrignaud -- Discovery of Boceprevir and Narlaprevir: A Case Study for Role of Structure-Based Drug Design / Srikanth Venkatraman, Andrew Prongay, George F Njoroge -- A New-Generation Uric Acid Production Inhibitor: Febuxostat / Ken Okamoto, Shiro Kondo, Takeshi Nishino.
  • 1998From: Google Books
    Office of Applied Studies.
    Also available: Print – 1998
  • 2007From: Springer
    Alain F. Zuur, Elena N. Ieno, Graham M. Smith.
  • Zachary S. Pincus.
    PrintStatus: Not Checked OutLane Catalog Record
  • 2015From: Springer
    Masami Tatsuno, editor.
    Since information in the brain is processed by the exchange of spikes among neurons, a study of such group dynamics is extremely important in understanding hippocampus dependent memory. These spike patterns and local field potentials (LFPs) have been analyzed by various statistical methods. These studies have led to important findings of memory information processing. For example, memory-trace replay, a reactivation of behaviorally induced neural patterns during subsequent sleep, has been suggested to play an important role in memory consolidation. It has also been suggested that a ripple/sharp wave event (one of the characteristics of LFPs in the hippocampus) and spiking activity in the cortex have a specific relationship that may facilitate the consolidation of hippocampal dependent memory from the hippocampus to the cortex. The book will provide a state-of-the-art finding of memory information processing through the analysis of multi-neuronal data. The first half of the book is devoted to this analysis aspect. Understanding memory information representation and its consolidation, however, cannot be achieved only by analyzing the data. It is extremely important to construct a computational model to seek an underlying mathematical principle. In other words, an entire picture of hippocampus dependent memory system would be elucidated through close collaboration among experiments, data analysis, and computational modeling. Not only does computational modeling benefit the data analysis of multi-electrode recordings, but it also provides useful insight for future experiments and analyses. The second half of the book will be devoted to the computational modeling of hippocampus-dependent memory.
  • 2012From: Wiley
    edited by Hanns-Christian Mahler, Wim Jiskoot.
    The critical need for robust assays for quantitation and characterization of aggregates of therapeutic proteins -- Separation based analytical methods for measuring protein aggregation -- Laser light scattering-based techniques used for the characterization of protein therapeutics -- Online detection methods and emerging techniques for soluble aggregates in protein pharmaceuticals -- Analytical methods to measure sub-visible particulates -- Detection of visible particles in parenteral products -- Characterization of aggregates and particles using emerging techniques -- Ultraviolet absorption spectroscopy -- Fluorescence spectroscopy to characterize protein aggregates and particles -- Infrared spectroscopy to characterize protein aggregates -- Raman microscopy for characterization of particles -- Microscopic methods for particle characterization in protein pharmaceuticals -- Comparison of methods for soluble aggregate detection and size characterization -- Protein purification and its relation to protein aggregation and particles -- Formulation development and its relation to protein aggregation and particles.
  • 2011From: ScienceDirect
    edited by Eleftheria Zeggini, Andrew Morris.
    According to the National Institute of Health, a genome-wide association study is defined as any study of genetic variation across the entire human genome that is designed to identify genetic associations with observable traits (such as blood pressure or weight), or the presence or absence of a disease or condition. Whole genome information, when combined with clinical and other phenotype data, offers the potential for increased understanding of basic biological processes affecting human health, improvement in the prediction of disease and patient care, and ultimately the realization of the promise of personalized medicine. In addition, rapid advances in understanding the patterns of human genetic variation and maturing high-throughput, cost-effective methods for genotyping are providing powerful research tools for identifying genetic variants that contribute to health and disease. This burgeoning science merges the principles of statistics and genetics studies to make sense of the vast amounts of information available with the mapping of genomes. In order to make the most of the information available, statistical tools must be tailored and translated for the analytical issues which are original to large-scale association studies. This book will provide researchers with advanced biological knowledge who are entering the field of genome-wide association studies with the groundwork to apply statistical analysis tools appropriately and effectively. With the use of consistent examples throughout the work, chapters will provide readers with best practice for getting started (design), analyzing, and interpreting data according to their research interests. Frequently used tests will be highlighted and a critical analysis of the advantages and disadvantage complimented by case studies for each will provide readers with the information they need to make the right choice for their research.
  • 2014From: CRCnetBASE
    Guanyu Wang.
    Food intake and energy metabolism -- Glucose homeostasis -- Optimal glucose homeostasis -- Bistability as a fundamental phenomenon -- Biomolecular network -- P13K-AKT-TOR pathway -- Diseases related to metabolism -- Mathematical modeling of the P13K-AKT-TOR Pathway -- Fundamental decomposition -- Normal phenotype -- Disease phenotypes -- Tao of diseases.
  • Mohamed M. Shoukri , Mohammad A. Chaudhary.
    PrintStatus: Not Checked OutLane Catalog Record
  • John Lawrence Sanders.
    Global analysis of post-translational modifications (PTMs) by mass spectrometry facilitates interrogation of complex signaling networks. We have utilized this technology and developed analytical tools to combine peptide level data into high confidence PTM site identifications and to assess the quality of quantification measurements. We have applied this workflow in order to study three systems: 1) mitochondrial acetylation and phosphorylation during cardiac ischemia, 2) phosphorylation regulation Toxoplasma gondii egress from host cells, and 3) early phosphorylation events during hedgehog signaling. 1. Acetylation is a highly abundant modification in the mitochondrion, but we lack a general understanding of both its regulation and functional relevance, especially with regard to the acetyltransfer mechanism. To explore the nature of mitochondrial acetylation, we compared several features of mitochondrial phosphorylation and acetylation sites, showcasing stark differences between these two PTMs. We found that mitochondrial acetylation is biased towards ordered secondary protein structures, and that acetylation and succinylation modify the same residues in an unbiased, unenriched sample. We suggest that these results are consistent with low levels of background, non-functional acetylation. In order to understand acetylation regulation, we must know the mechanism of acetyl transfer. Our findings indicate that either a putative mitochondrial acetyltransferase or family of acyltransferases exist that operate non-specifically and recognize substrates in a matter entirely distinct from kinases, or else that a substantial fraction of observed mitochondrial lysine acylation results from non-enzymatic modification by acyl-CoAs. 2. We report the first phosphoproteomes of T. gondii and P. falciparum. These datasets demonstrated for the first time tyrosine phosphorylation in P. falciparum, and unusual phosphorylation-site motifs for P. falciparum. We observed extensive phosphorylation beyond the intercellular parasites' boundaries. In a follow-up study in T. gondii, we focused on the role of calcium-dependent protein kinase 3 (TgCDPK3), which regulates parasite egress from the host cell in the presence of a calciumionophore. We measured relative phosphorylation site abundance in wild type and TgCDPK3 mutant and knock-out parasites by quantitative mass-spectrometry using stable isotope-labeling by amino acids in cell culture (SILAC). Our results demonstrate that TgCDPK3 regulates several functions in addition to egress. We also observed novel phosphorylation events on proteins predicted to play a role in egress, and which implicate TgCDPK3 in regulating other calcium-dependent signaling pathways, including TgCDPK1. 3. Finally, we have initiated a study of the early phosphorylation signaling events in response to hedgehog signaling. Here, we report preliminary results that implicate a kinase, casein kinase 2 (CK2), in hedgehog signaling. Work is currently being undertaken in the Scott Lab to further characterize the role of CK2 in hedgehog signaling while we analyze biological replicates to expand proteome coverage and validate our initial hits.
  • Daniel Edmund Newburger.
    The study of genomic variation within human populations is critical for elucidating the genetic factors that contribute to disease. Identifying and characterizing the genetic architecture of disease advances clinical care by facilitating the development of novel diagnostic tools, the identification of new therapeutic targets, and the practice of personalized treatment for genetic syndromes. The massive volume of genetic data generated by modern genotyping technologies, combined with the informatics challenges of filtering and interpreting these noisy measurements, represent significant obstacles to genomic research. These technical issues necessitate the development of computationally efficient methodologies that leverage raw genotype data for the comparative genomic analysis of complex phenotypes across human subpopulations. In this dissertation, I describe my contributions towards the biomedical study of genetic syndromes using high-throughput genotyping technologies. First, I discuss methods for studying the genome evolution of pre-malignant cancer lesions during progression to breast cancer. Second, I describe algorithms for performing highly accurate variant validation in genomic studies using next generation sequencing. Finally, I present methods for identifying novel disease susceptibility loci in complex diseases using identity by descent mapping in large case-control cohorts.
  • 2007From: CRCnetBASE
    edited by Malcolm Whitman, Amy K. Sater.
  • v. 1-3, 1984From: CRCnetBASE
    George A. Milliken, Dallas E. Johnson.
    v. 1. Designed experiments -- v. 2. Nonreplicated experiments -- v. 3. Analysis of covariance
  • 2010From: Atypon
    Fábio J. Ayres, Rangaraj M. Rangayyan, and J.E. Leo Desautels.
    The presence of oriented features in images often conveys important information about the scene or the objects contained; the analysis of oriented patterns is an important task in the general framework of image understanding. As in many other applications of computer vision, the general framework for the understanding of oriented features in images can be divided into low- and high-level analysis. In the context of the study of oriented features, low-level analysis includes the detection of oriented features in images; a measure of the local magnitude and orientation of oriented features over the entire region of analysis in the image is called the orientation field. High-level analysis relates to the discovery of patterns in the orientation field, usually by associating the structure perceived in the orientation field with a geometrical model. This book presents an analysis of several important methods for the detection of oriented features in images, and a discussion of the phase portrait method for high-level analysis of orientation fields. In order to illustrate the concepts developed throughout the book, an application is presented of the phase portrait method to computer-aided detection of architectural distortion in mammograms.
  • 2010From: Springer
    Sonja Grün, Stefan Rotter, editors.
    Part I: Basic Spike Train Statistics -- 1 Stochastic Models of Spike Trains -- 2 Estimating the Firing Rate -- 3 Analysis and Interpretation of Interval and Count Variability in Neural Spike Trains -- 4 Processing of Phase-Locked Spikes and Periodic Signals -- Part II: Pairwise Comparison of Spike Trains -- 5 Pair-Correlation in the Time and Frequency Domain -- 6 Dependence of Spike-Count Correlations on Spike-Train Statistics and Observation Time Scale -- 7 Spike Metrics -- 8 Gravitational Clustering -- Part III: Multiple-Neuron Spike Patterns -- 9 Spatio-Temporal Patterns -- 10 Unitary Event Analysis -- 11 Information Geometry of Multiple Spike Trains -- 12 Higher-Order Correlations and Cumulants -- Part IV: Population-Based Approaches -- 13 Information Theory and Systems Neuroscience -- 14 Population Coding -- 15 Stochastic Models for Multivariate Neural Point Processes: Collective Dynamics and Neural Decoding -- Part V: Practical Issues -- 16 Simulation of Stochastic Point Processes with Defined Properties -- 17 Generation and Selection of Surrogate Methods for Correlation Analysis -- 18 Bootstrap Tests of Hypotheses -- 19 Generating Random Numbers -- 20 Practically Trivial Parallel Data Processing in a Neuroscience Laboratory -- Index.
  • 2008From: CRCnetBASE
    editor, José L. Tadeo.
    Pesticides: classification and properties / José L. Tadeo, Consuelo Sánchez-Brunete, Lorena González -- Sample handling of pesticides in food and environmental samples / Esther Turiel, Antonio Martín-Esteban -- Analysis of pesticides by chromatographic techniques coupled with mass spectrometry / Simon Hird -- Immunoassays and biosensors / Jeanette M. Van Emon ... [et al.] -- Quality assurance / Árpád Ambrus -- Determination of pesticides in food of vegetal origin / Frank J. Schenck, Jon W. Wong -- Determination of pesticides in food of animal origin / Antonia Garrido Frenich, Jose Luis Martinez, Adrian Covaci -- Determination of pesticides in soil / Consuelo Sánchez-Brunete, Beatriz Albero, José L. Tadeo -- Determination of pesticides in water / Jay Gan, Svetlana Bondarenko -- Sampling and analysis of pesticides in the atmosphere / Maurice Millet -- Levels of pesticides in food and food safety aspects / Kit Granby ... [et al.] -- Monitoring of pesticides in the environment / Ioannus Konstantinou ... [et al.].
  • Wendy Ching.
    PrintStatus: Not Checked OutLane Catalog Record
  • Mark A. McElwain.
    Only a few signaling pathways control the majority of biological processes throughout animal development and homeostasis, indicating that each pathway regulates multiple processes. The Wnt family of secreted ligands is one interesting and important example of this paradigm. Evidence abounds that Wnt signaling impacts numerous biological events including embryonic patterning, stem cell self- renewal, cell proliferation, and tissue regeneration. While only a few Wnt proteins have been extensively characterized, it is likely that each family member signals to control a variety of critical biological processes; therefore, it is clear that by understanding the signaling mechanism used by a single Wnt protein, we can understand how many aspects of biology are regulated. WntD is one of 7 Wnt homologs encoded by the Drosophila genome. While most of these Wnt proteins likely signal through a pathway dependent on the [Beta]-catenin homolog Armadillo (Arm), WntD very likely utilizes an Arm-independent mechanism to control embryonic dorsal/ventral (D/V) patterning, migration of the primordial germ cells (PGC) to the embryonic gonad, and the innate immune response. It is therefore of great interest to identify genes involved in this signal transduction pathway and better characterize the effect WntD has on these important biological processes. To this end, a suppressor/enhancer deficiency screen based upon the role of WntD in D/V patterning was previously performed in the laboratory. From this screen, 30 strong candidates for suppressors and 13 strong candidates for enhancers were identified. Here, I present further characterization of two candidate WntD pathway members identified in the screen: Fz4, a likely WntD receptor and Dcerk, a lipid kinase. I show by both in vitro and in vivo assays that both Fz4 and Dcerk function in the WntD signal transduction pathway, and present evidence suggesting that this WntD-Fz4-Dcerk signaling cassette is utilized during both D/V patterning and PGC migration, yet another instance of a single signaling cascade mediating multiple developmental events. Interestingly, I show that both of these novel WntD signal transducers appear to act redundantly with a homologous protein: in both D/V patterning and PGC migration, WntD likely signals through Fz3 and Fz4 receptors to activate the lipid kinases Dcerk and Dmulk. I further show, in collaboration with the Saba Laboratory at Children's Hospital Oakland Research Institute, that these kinases are necessary for wild-type ceramide-1-phosphate (C1P) levels in the adult, and either is sufficient to increase embryonic C1P levels, suggesting that both Dcerk and Dmulk are bona fide ceramide kinases. My data linking WntD-ceramide kinase signaling to PGC migration is consistent with a model in which WntD signaling is responsible for generation of optimal levels of embryonic C1P, which is likely to be the long-undiscovered substrate that is formed into a gradient by the lipid phosphate phosphatases encoded by Wunen and Wunen2. Future experiments will be required to further test this model. Importantly, these results may suggest a mechanism for the regulation of a broad range of migratory cell types, including other cells that migrate to generate a specific tissue or organ during embryonic development, and immune cells that must travel long distances to fight off infections.
  • 2008From: Springer
    Boris Sobolev, Lisa Kuramoto.
  • 2007From: CRCnetBASE
    edited by Pascal Kintz.
    Drug incorporation into hair / Robert Kronstrand and Karen Scott -- Passive exposure, decontamination procedures, cutoffs, and bias: pitfalls in the interpretation of hair analysis results for cocaine use / David A. Kidwell and Frederick P. Smith -- Opioids testing in hair / Michel Yegles and Robert Wennig -- Hair analysis for cocaine / Carmen Jurado -- Determination of cannabinoids in human hair / Michael Uhl -- Amphetamine determination in hair / Vincent Cirimele -- Pharmaceuticals in hair / Marjorie Cheze, Marc Deveaux, Gaelle Duffort, Francis Billault, and Gilbert Pepin -- Screening strategies in hair analysis on drugs / Hans Sachs -- Clinical applications of hair analysis / Simona Pichini, Oscar Garcia-Algar, and Rafael de la Torre -- Hair in postmortem toxicology / Robert Kronstrand and Henrik Druid -- Detection of doping agents in human hair / Pascal Kintz -- Applications of hair in drug-facilitated crime evidence / Marion Villain -- Application of hair in driving-license regranting / Manfred R. Moeller, Hans Sachs, and Fritz Pragst -- Alcohol markers in hair / Fritz Pragst and Michel Yegles -- Workplace drug testing using hair samples / Thomas Cairns, Michael Schaffer, and Virginia Hill -- Metals / Jean-Pierre Goulle.
  • 2012From: Wiley
    edited by Sergio Caroli, Gyula Záray.
    Part I Exploring fundamentals -- Good clinical practice principles: legal background and applicability / Umberto Filibeck, Angela Del Vecchio, and Fabrizio Galliccia -- Clinical chemistry and the quest for quality / Sergio Caroli -- Uncertainty in clinical chemistry measurements including preanalytical variables / Marit Sverresdotter Sylte, Tore Wentzel-Larsen, and Bjorn J. Bolann -- The role and significance of reference values in the identification and evaluation of trace elements from diet / Pietro Apostoli and Maria Cristina Ricossa -- Sample collection, storage, and pretreatment in clinical chemistry / Andrew Taylor -- Metal toxicology in clinical, forensic, and chemical pathology / Jose A. Centeno [and others] -- Part II Selected applications -- Elemental speciation in clinical sciences / Douglas M. Templeton -- The role of analytical chemistry in the safety of drug therapy / Sandor Gorog -- Analytical techniques and quality control of pharmaceuticals / Fedele Manna, Francesca Rossi, and Rossella Fioravanti -- Detection of drugs in biological fluids for antidoping control / Sabina Strano Rossi and Marcello Chiarotti -- The applicability of plasma-based techniques to biological monitoring / Ilse Steffan and Goran Vujicic -- Atomic spectrometric techniques for the analysis of clinical samples / Pilar Bermejo Barrera, Antonio Moreda Pineiro, and Maria del Carmen Barciela Alonso -- Applications of ICP-MS in human biomonitoring studies / Peter Heitland and Helmut D. Koster -- Molybdenum in biological samples and clinical significance of serum molybdenum / Munehiro Yoshida -- Application of organometallic speciation in clinical studies / Bin He [and others] -- Biosensors for drug analysis / Daniela Deriu and Franco Mazzei -- Bioimaging of metals and proteomic studies of clinical samples by laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) / J. Sabine Becker and J. Susanne Becker -- Applications of LC-MS/MS in clinical laboratory diagnostics / Uta Ceglarek, Georg Martin Fiedler, and Joachim Thiery -- Metabolomics using UPLC/HPLC-tandem mass spectrometry in diagnosis and research of inherited metabolic diseases / Willem Kulik and Andre B.P. van Kuilenburg -- Biomarkers of oxidative stress in plasma and urine / Papasani V. Subbaiah -- The use of x-ray techniques in medical research / Imre Szaloki, Gyula Zaray, and Norbert Szoboszlai -- Part III Future trends -- A new tool based on the use of stable isotopes and isotope pattern deconvolution (IPD)-ICP-MS for nutritional and clinical studies / Hector Gonzalez Iglesias, Maria Luisa Fernandez-Sanchez, and Alfredo Sanz-Medel -- Breath analysis: analytical methodologies and clinical applications / Alessio Ceccarini [and others] -- Proteo-metabolomic strategies in the future of drug development / Uwe Christians [and others] -- Basics in laboratory medicine: past, present, and future / Lorand A. Debreczeni, Anna Kovacsay, and Sandor Nagy.
  • 2011From: Springer
    by Rajan Katoch.
    Advances in biochemistry now allow us to control living systems in ways that were undreamt of a decade ago. This volume guides researchers and students through the full spectrum of experimental protocols used in biochemistry, plant biology and biotechnology.
  • 2015From: ScienceDirect
    edited by James L. Cole.
    Analytical Ultracentrifugation, the latest volume in Methods in Enzymology, focuses on analytical ultracentrifugation. The scope of this technique has greatly expanded in recent years due to advances in instrumentation, algorithms and software. This volume describes the latest innovations in the field and in the applications of analytical ultracentrifugation in the analysis of macromolecules, macromolecular assemblies, and biopharmaceuticals.
  • 2015From: Wiley
    [edited by] Dongmei Chen, Bernard Moulin, Jianhong Wu.
    Introduction to analyzing and modeling spatial and temporal dynamics of infectious diseases / Dongmei Chen, Bernard Moulin, Jianhong Wu -- Modeling the spread of infectious diseases : a review / Dongmei Chen -- West Nile virus : a narrative from bioinformatics and mathematical modeling studies / U.S.N. Murty, Amit Kumar Banerjee and Jianhong Wu -- West Nile virus risk assessment and forecasting using statistical and dynamical models / Ahmed Abdelrazec, Yurong Cao, Xin Gao, Paul Proctor, Hui Zheng, and Huaiping Zhu -- Using mathematical modeling to integrate disease surveillance and global air transportation data / Julien Arino and Kamran Khan -- Mathematical modeling of malaria models with spatial effects / Daozhou Gao and Shigui Ruan -- Avian influenza spread and transmission dynamics / Lydia Bourouiba, Stephen Gourley, Rongsong Liu, John Takekawa, and Jianhong Wu -- Analyzing the potential impact of bird migration on the global spread of H5N1 avian influenza (2007-2011) using spatio-temporal mapping methods / Heather Richardson and Dongmei Chen -- Cloud computing-enabled cluster detection using a flexibly shaped scan statistic for real-time syndromic surveillance / P. Belanger and K. Moore -- Mapping the distribution of malaria : current approaches and future directions / L.R. Johnson, K.D. Lafferty, A. McNally, E. Mordecai, K. Paaijmans, S. Pawar, S.J. Ryan -- Statistical modeling of spatio-temporal infectious disease transmission / Rob Deardon, Xuan Fang and Grace Pui Sze Kwong -- Spatio-temporal dynamics of schistosomiasis in China : bayesian-based geostatistical analysis / Zhi-Jie Zhang -- Spatial analysis and statistical modeling of 2009 H1N1 pandemic in the greater Toronto area / Frank Wen, Dongmei Chen, Anna Majury -- West Nile virus mosquito abundance modeling using a non-stationary spatio-temporal geostatistics / Eun-Hye Yoo, Dongmei Chen, Curtis Russel -- Spatial pattern analysis of multivariate disease data / Cindy X. Feng and Charmaine Dean -- The zoonosismags project (part 1) : population-based geosimulation of zoonoses in an informed virtual geographic environment / Bernard Moulin, Mondher Bouden, Daniel Navarro -- Zoonosismags project (part 2) : complementarity of a rapid-propotyping tool and of a full-scale geosimulator for population-based geosimulation of zoonoses / Bernard Moulin, Daniel Navarro, Dominic Marcotte, Said Sedrati -- Web-mapping and behaviour pattern extraction tools to assess lyme disease risk for humans in peri-urban forests / Hedi Haddad, Bernard Moulin, Franck Manirakiza Christelle Maha, Vincent Godard and Samuel Mermet -- An integrated approach for communicable disease geosimulation based on epidemiological, human mobility and public intervention models / Hedi Haddad, Bernard Moulin, Marius Thariault -- Smartphone trajectories as data sources for agent-based infection spread modeling / M.R. Friesen and R.D. McLeod.
  • Jin Woo Im.
    Using U.S. Department of Veterans Affairs (VA) records, this dissertation explores the staffing mix in substance use disorder treatment programs (SUDTPs) and the effectiveness of the current clinical practice guideline in reducing suicide risk associated with opioid therapy. The VA treats a large number of Veterans diagnosed with substance use disorders (SUDs) in four types of specialized SUDTPs at an annual cost of more than $350 million. The staffing mixes were not significantly different from 2001 to 2003, the years under review. However, given differences in treatment focus and provided services, the four types of SUDTPs may require different staffing mixes. We demonstrate how cost-effective staffing mixes for each type of VA SUDTP can be defined empirically. We derive prediction functions for benefits and costs based on patients' treatment outcomes at VA SUDTPs nationally from 2001 to 2003, and use them to formulate optimization problems to determine recommended staffing mixes that maximize net benefits per patient for four types of SUDTPs while conforming to limits of current practice. Compared to the actual staffing mixes in 2001-2003, the recommended staffing mixes would lower treatment costs while improving patient outcomes. We also introduce an approach to building a decision support system for staffing each type of SUDTP reflecting the dynamics of effectiveness and costs associated with the staffing changes. Compared to the actual staffing mixes, the staffing mixes suggested by the staffing decision support system are expected to treat significantly more Veteran patients under the existing staffing budget while improving patient outcomes. We also examine associations between adherence to guideline recommendations and the risk of suicide attempt based on Veterans Health Administration (VHA) records. Opioid therapy is often provided to reduce chronic pain in at-risk patients. Unfortunately, available opioid medications have been also used as a means for attempting suicide. In 2010, the VHA and the Department of Defense released a jointly developed clinical practice guideline (CPG) to reduce the risk of adverse events such as suicide attempt in patients prescribed opioids, primarily based on expert consensus. We conduct multivariate mixed-effects logistic regression analyses to define the associations between facility-level CPG adherence rates and risk of suicide attempt while controlling for the associations between individual-level delivery of CPG-based services and the risk of suicide attempt. Major findings include the following: suicide attempts were negatively associated with facility-level adherence rates for both consistent urine drug screenings and follow-up appointments, and were positively associated with facility-level risky sedative co-prescription rates.
  • 2010From: Karger
    volume editor, Johannes Ring.
    History and epidemiology -- History and classification of anaphylaxis -- Epidemiology of anaphylaxis -- Mechanisms -- T-cell response to allergens -- Anaphylaxis: mechanisms of mast cell activation -- Kinins, airway obstruction, and anaphylaxis -- Role for basophils in systemic anaphylaxis -- Human cardiac mast cells in anaphylaxis -- Diagnosis and clinical symptomatology -- Mastocytosis -- In vitro diagnosis of anaphylaxis -- Allergens and elicitors -- Insect venoms -- Classification and pathophysiology of radiocontrast media hypersensitivity -- Analgesics -- Anaphylaxis to general anesthetics -- Anaphylactic reactions to local anesthetics -- Treatment and prevention -- Anaphylaxis: acute treatment and management -- Epinephrine (adrenaline) in anaphylaxis.
  • 2011From: Springer
    Mariana C. Castells, editor.
    Definition and criteria for the diagnoses of anaphylaxis -- An epidemiological approach to reducing the risk of fatal anaphylaxis -- Pathophysiology and organ damage in anaphylaxis -- Mast cells: effector cells of anaphylaxis -- Basophils in anaphylaxis -- Protease mediators of anaphylaxis -- Aspirin and NSAID reactions: diagnosis, pathophysiology, and management -- IgE-dependent and independent effector mechanisms in human and murine anaphylaxis -- Food-induced anaphylaxis -- Antibiotic-induced anaphylaxis -- Anaphylaxis during radiological procedures and in the peri-operative setting -- Hymenoptera-induced hypersensitivity reactions and anaphylaxis -- Idiopathic anaphylaxis -- Exercise-induced anaphylaxis and food-dependent exercise-induced anaphylaxis -- Mastocytosis and mast cell activation syndromes presenting as anaphylaxis -- Anaphylaxis in mastocytosis -- Flushing and urticarial syndromes presenting as anaphylaxis -- Pharmacologic management of acute anaphylaxis -- Drug desensitizations in the management of allergy and anaphylaxis to chemotherapeutic agents and monoclonal antibodies -- Rapid desensitizations for antibiotic-induced hypersensitivity reactions and anaphylaxis -- Induction of tolerance for food-induced anaphylaxis -- Management of anaphylaxis: relevance of causes and future trends in treatment.
  • 2011From: Springer
    Kwan-Leung Chan, John P. Veinot.
    General anatomy of the heart in the chest -- Age-related cardiac changes -- Aortic valve -- Mitral valve -- Tricuspid and pulmonary valve -- Cardiomyopathies -- Ischemic heart disease -- Right ventricular diseases -- Diseases of the aorta -- Pericardial diseases -- Prosthetic heart valves -- Infective endocarditis and related conditions -- Neoplasm, cardiac tumor -- Congenital heart disease -- Cardiac source of embolism -- Assessment of diastolic function -- Cardiac involvement by systemic diseases -- Interventional procedures.
  • 2009From: Thieme
    Cary D. Alberstone, Edward C. Benzel, Imad M. Najm, Michael P. Steinmetz ; illustrators, Joseph Kanasz, Nichael Norviel.
    Development and developmental disorders -- Neuroembryology -- Regional anatomy and related syndromes -- Peripheral nerves -- Plexuses -- Nerve roots and spinal nerves -- Spinal cord -- Brainstem -- Cranial nerves -- Cerebellum -- Thalamus -- Hypothalamus -- Basal ganglia -- Limbic system -- Cerebral cortex -- System-based anatomy and differential diagnosis -- Somatosensory system -- Visual system -- Auditory system -- Ocular motor system -- Motor system -- Autonomic nervous system -- Consciousness -- Fluid-system anatomy and function -- Vascular system -- Cerebrospinal fluid.
  • 2010From: Springer
    William C. Wood, C.A. Staley, John E. Skandalakis (eds.).
  • 2014From: Springer
    Vincent Di Marino, Hubert Lepidi.
    "This eagerly awaited book offers a unique, comprehensive scientific study of the anatomy of the organ of female sexual pleasure. The authors use macroscopic and microscopic research to guide the reader from the glans, the visible part of the clitoris, where they explore the impressive sensory corpuscles, to the hidden roots of the bulbo-clitoral organ. They show its complexity, its exact location within the external genitalia and its intimate relationship with the urethro-vaginal pyramid. They also remind us that throughout history there has been a failure to understand this organ, and explain that this misunderstanding remains the cause of persistent excisions, criminal mutilating practices that have not yet been eradicated. Using extensive iconography, they demonstrate throughout this book that the bulbo-clitoral organ is an exceptional natural treasure that every woman possesses and that every man should know well."--Publisher's website.
  • 2008From: Springer
    H. Endo, R. Frey (eds.).
    Head anatomy of male and female Mongolian gazelle - a striking example of sexual dimorphism / R. Frey ... [et al.] -- Anatomical peculiarities of the vocal tract in felids / G.E. Weissengruber ... [et al.] -- The anatomical foundation for multidisciplinary studies of animal limb function : examples from dinosaur and elephant limb imaging studies / J.R. Hutchinson ... [et al.] -- Locomotion-related femoral trabecular architectures in primates - high resolution computed tomographies and their implications for estimations of locomotor preferences of fossil primates / H. Scherf -- Three-dimensional imaging of the manipulating apparatus in the lesser panda and the giant panda / H. Endo ... [et al.] -- Using CT to peer into the past : 3D visualization of the brain and ear regions of birds, crocodiles, and nonavian dinosaurs / L.M. Witmer ... [et al.] -- Evolutionary morphology of the autonomic cardiac nervous system in non-human primates and humans / T. Kawashima and H. Sasaki.
  • Carmine D. Clemente.
    PrintStatus: Not Checked OutLane Catalog Record
  • 2015From: Springer
    Amgad S. Hanna ; illustrations by Mark Ehlers.
    Upper Body Nerves: Supraclavicular Brachial Plexus -- Infraclavicular Brachial Plexus -- Musculocutaneous Nerve -- Median Nerve -- Ulnar Nerve -- Axillary Nerve -- Radial Nerve -- Suprascapular Nerve -- Long Thoracic and Thoracodorsal Nerves -- Intercostal Nerves. Lower Body Nerves: Lumbosacral Plexus -- Femoral Nerve -- Lateral Femoral Cutaneous Nerve -- Sciatic Nerve Technical Notes.
  • Edell, Dean.
    PrintStatus: Not Checked OutLane Catalog Record
  • 2014From: Wiley
    Harold Ellis, Andrew Lawson.
    Part 1. The respiratory pathway, lungs, thoracic wall and diaphragm -- part 2. The heart and great veins of the neck -- part 3. The vertebral canal and its contents -- part 4. The peripheral nerves -- part 5. The autonomic nervous system -- part 6. The cranial nerves -- part 7. Miscellaneous zones of interest -- part 8. The anatomy of pain.
  • W. Henry Hollinshead.
    PrintStatus: Not Checked OutLane Catalog Record
    v.1, The head and neck ; v. 3. The back and limbs.
  • [edited by] Robert M. Klein George C. Enders.
    PrintStatus: Not Checked OutLane Catalog Record
  • [edited by] Robert M. Klein, George C. Enders.
    PrintStatus: Not Checked OutLane Catalog Record
  • 2015From: OSO
    Jaekyung Lee.
    Through the lens of interdisciplinary and systems perspectives, The Anatomy of Achievement Gaps offers an expert critical analysis of the underachievement problems plaguing the American education system today.
  • Howard Markel.
    The astonishing account of the decades-long cocaine use of Sigmund Freud and William Halsted. The author discusses the physical and emotional damage caused by the constant use of the then-heralded wonder drug, and of how each man ultimately changed the world in spite of it--or because of it.
  • Stephanie Marie Melillo.
    Striding bipedalism is a mode of locomotion that defines our lineage. Bipedality freed the hands, arms and shoulders from the mechanical constraints of locomotion, an evolutionary innovation that has had an obvious impact on our species' fitness. As I will discuss in this dissertation, the shoulder blade (scapula) is shaped to optimize use of the upper limb in certain positions. Our closest living relatives (chimpanzees and gorillas) possess adaptations that likely increase efficiency in overhead use of the arms, as in forearm suspension or vertical climbing. The modern human shoulder, on the other hand, lacks such adaptations. This difference may reflect an evolutionary change in shape that occurred as our ancestors transitioned to a terrestrial way of life and became increasingly dexterous, eventually losing ancestral adaptations. On the other hand, recent discoveries suggest our lineage may have never possessed adaptations to suspension. Fossils from the shoulder of our early human ancestors are scarce. A recently discovered partial skeleton from Woranso-Mille (Afar Depression, Ethiopia), KSD-VP-1/1, preserves the oldest and most complete scapula of an adult Australopithecus afarensis individual. The intended contribution of this dissertation is to provide a comparative description of the new scapula (KSD-VP-1/1g) and to detail its implications for our understanding of anatomy and adaptation in the Australopithecus shoulder, and the evolutionary history of the modern human shoulder more generally.
  • by Henry Gray ... thoroughly revised and re-edited by Warren H. Lewis; illustrated with 1247 engravings [by] H. Lewis.
    Also available: Print – 1918
  • 2005/1965From: Jackson Lab
    Margaret J. Cook.
    Also available: Print – 2005/1965
  • 2016From: OSO
    Ron Sun.
  • 2007From: Springer
    Albert Burger, Duncan Davidson, Richard Baldock, editors.
    Existing anatomy ontologies for human, model organisms and plants -- Anatomical ontologies for model organisms : the fungi and animals / Jonathan Bard -- Plant structure ontology (PSO) : a morphological and anatomical ontology of flowering plants / Katica Ilic, ... [et al.] -- Anatomy for clinical terminology / Alan L. Rector -- The foundational model of anatomy ontology / Cornelius Rosse and José L. V. Mejino, Jr. -- Towards a disease ontology / Paul N. Schofield, Björn Rozell, Georgios V. Gkoutos -- Engineering and linking of anatomy ontologies -- Ontology alignment and merging / Patrick Lambrix, He Tan -- COBrA and COBrA-CT : ontology engineering tools / Stuart Aitken, Yin Chen -- XSPAN : a cross-species anatomy network / Albert Burger, Jonathan Bard -- Searching biomedical literature with anatomy ontologies / Thomas Wächter, ... [et al.] -- Anatomy ontologies and spatio-temporal atlases -- Anatomical ontologies : linking names to places in biology / Richard A. Baldock, Albert Burger -- Time in anatomy / Duncan Davidson -- The Edinburgh mouse atlas / Richard Baldock, Duncan Davidson -- The smart atlas : spatial and semantic strategies for multiscale integration of brain data / Maryann E. Martone, ... [et al.] -- Anatomy ontologies : modelling principles -- Modelling principles and methodologies : relations in anatomical ontologies / Fabian Neuhaus, Barry Smith -- Modeling principles and methodologies : spatial representation and reasoning / Thomas Bittner, ... [et al.] -- CARO : the common anatomy reference ontology / Melissa A. Haendel, ... [et al.]
  • Todd A. Swanson, Sandra I. Kim, Medina C. Kushen.
    PrintStatus: Not Checked OutLane Catalog Record
  • Claire Laurier Decoteau.
    "In the years since the end of apartheid, South Africans have enjoyed a progressive constitution, considerable access to social services for the poor and sick, and a booming economy that has made their nation into one of the wealthiest on the continent. At the same time, South Africa experiences extremely unequal income distribution, and its citizens suffer the highest prevalence of HIV in the world. As Archbishop Desmond Tutu has noted, "AIDS is South Africa's new apartheid." In Ancestors and Antiretrovirals, Claire Laurier Decoteau backs up Tutu's assertion with powerful arguments about how this came to pass. Decoteau traces the historical shifts in health policy after apartheid and describes their effects, detailing, in particular, the changing relationship between biomedical and indigenous health care, both at the national and the local level. Decoteau tells this story from the perspective of those living with and dying from AIDS in Johannesburg's squatter camps. At the same time, she exposes the complex and often contradictory ways that the South African government has failed to balance the demands of neoliberal capital with the considerable health needs of its population." -- Publisher's description.
  • 2014From: OSO
    edited by Darcia Narvaez, Kristin Valentino, Agustin Fuentes, James J. McKenna and Peter Gray.
    1. Children's development in light of evolution and culture / Darcia Narvaez [and four others] -- 2. Epigenetics of mammalian parenting / Frances A. Champagne. Commentary. As time goes by, a touch is more than just a touch / Eric E. Nelson -- 3. Nonhuman primate models of mental health : early life experiences affect developmental trajectories / Amanda M. Dettmer, Stephen J. Suomi, and Katie Hinde. Commentary. Look how far we have come : a bit on consilience in elucidating the role of caregivers in relationship to their developing primate infants and children / James J. McKenna -- 4. Relationships and resource uncertainty : cooperative development of Efe hunter-gatherer infants and toddlers / Gilda Morelli, Paula Ivey Henry, and Steffen Foerster. Commentary. Social connectedness versus mothers on their own : research on hunter-gatherer tribes highlights the lack of support mothers and babies receive in the United States / Kathleen Kendall-Tackett -- 5. Batek childrearing and morality / Karen L. Endicott and Kirk M. Endicott. Commentary. Parenting in the modern jungle / Michael Jindra -- 6. Cosleeping beyond infancy : culture, ecology, and evolutionary biology of bed sharing among Aka foragers and Ngandu farmers of Central Africa / Barry S. Hewlett and Jennifer W. Roulette. Commentary. Intertwining the influences of culture and ecology broadens a definition of the importance of closeness in care / Wendy Middlemiss -- 7. Environment of evolutionary adaptedness, rough-and-tumble play, and the selection of restraint in human aggression / Douglas P. Fry. Commentary. Evolutionary adaptation and violent aggression : from myths to realities / Riane Eisler -- 8. Play theory of hunter-gatherer egalitarianism / Peter Gray. Commentary. Comparative studies of social play, fairness, and fitness : what we know and where we should be heading / Marc Bekoff -- 9. Incentives in the family I : the family firm, an evolutionary/economic theory for parent-offspring relations / Joan Roughgarden and Zhiyuan Song -- 10. Preliminary steps toward addressing the role of nonadult individuals in human evolution / Agustín Fuentes. Commentary. Conflict and evolution / Melvin Konner -- 11. Child maltreatment and early mother-child interactions / Kristin Valentino, Michelle Comas, and Amy K. Nuttall. Commentary. Ancestral attachment : how the evolutionary foundation of attachment informs our understanding of child maltreatment interventions / Alyssa N. Crittenden -- 12. Importance of the developmental perspective in evolutionary discussions of post-traumatic stress disorder / Robyn Bluhm and Ruth A. Lanius. Commentary. Modeling of complex post-traumatic stress disorder can benefit from careful integration of evolutionary and developmental accounts / Pierre Lienard -- 13. From the emergent drama of interpretation to enscreenment / Eugene Halton. Commentary. Darwinism and children / Jonathan Marks -- 14. Childhood environments and flourishing / Tracy R. Gleason and Darcia Narvaez -- 15. Postscript. Back to the future / James J. McKenna.
  • 2012From: Springer Protocols
    edited by Beth Shapiro, Michael Hofreiter.
    Setting up an ancient DNA laboratory / Tara L. Fulton -- A phenol-chloroform protocol for extracting DNA from ancient samples / Ross Barnett and Greger Larson -- DNA extraction of ancient animal hard tissue samples via adsorption to silica particles / Nadin Rohland -- Case study : recovery of ancient nuclear DNA from toe pads of the extinct passenger pigeon / Tara L. Fulton, Stephen M. Wagner, and Beth Shapiro -- Extraction of DNA from paleofeces / Melanie Kuch and Hendrik Poinar -- DNA extraction from keratin and chitin / Paula F. Campos and Thomas M.P. Gilbert -- Case study : ancient sloth DNA recovered from hairs preserved in paleofeces / Andrew A. Clack, Ross D.E. MacPhee, and Hendrik N. Poinar -- Ancient DNA extraction from soils and sediments / James Haile -- DNA extraction from fossil eggshell / Charlotte L. Oskam and Michael Bunce -- Ancient DNA extraction from plants / Logan Kistler -- DNA extraction from formalin-fixed material / Paula F. Campos and Thomas M.P. Gilbert -- Case study : ancient DNA recovered from Pleistocene-age remains of a Florida armadillo / Brandon Letts and Beth Shapiro -- Nondestructive DNA extraction from museum specimens / Michael Hofreiter -- Case study : using a nondestructive DNA extraction method to generate mtDNA sequences from historical chimpanzee specimens / Elmira Mohandesan, Stefan Prost, and Michael Hofreiter -- PCR amplification, cloning, and sequencing of ancient DNA / Tara L. Fulton and Mathias Stiller -- Quantitative real-time PCR in aDNA research / Michael Bunce, Charlotte L. Oskam, and Morten E. Allentoft -- Multiplex PCR amplification of ancient DNA / Mathias Stiller and Tara L. Fulton -- Preparation of next-generation sequencing libraries from damaged DNA / Adrian W. Briggs and Patricia Heyn -- Generating barcoded libraries for multiplex high-throughput sequencing / Michael Knapp, Mathias Stiller, and Matthias Meyer -- Case study : targeted high-throughput sequencing of mitochondrial genomes from extinct cave bears via direct multiplex PCR sequencing (DMPS) / Mathias Stiller -- Target enrichment via DNA hybridization capture / Susanne Horn -- Case study : enrichment of ancient mitochondrial DNA by hybridization capture / Susanne Horn -- Analysis of high-throughput ancient DNA sequencing data / Martin Kircher -- Phylogenetic analysis of ancient DNA using BEAST / Simon Y.W. Ho.
  • Vivian Nutton.
    1. Sources and scope -- 2. Patterns of disease -- 3. Before Hippocrates -- 4. Hippocrates, the Hippocratic Corpus and the defining of medicine -- 5. Hippocratic theories -- 6. Hippocratic practices -- 7. Religion and medicine in fifth- and fourth-century Greece -- 8. From Plato to Praxagoras -- 9. Alexandria, anatomy and experimentation -- 10. Hellenistic medicine -- 11. Rome and the transplantation of Greek medicine -- 12. The Consequences of empire: pharmacology, surgery and the Roman army -- 13. The Rise of Methodism -- 14. Humoral alternatives -- 15. The Life and career of Galen -- 16. Galenic medicine -- 17. All sorts and conditions of (mainly) men -- 18. Medicine and the religions of the Roman Empire -- 19. Medicine in the Later Roman Empire -- 20. Conclusion.
  • editor-in-chief, Thomas E. Andreoli ; editors, Charles C.J. Carpenter, Robert C. Griggs, and Ivor J. Benjamin.
    PrintStatus: Not Checked OutLane Catalog Record
  • 2016From: ClinicalKey
    editor-in-chief, Ivor J. Benjamin ; editors, Robert C. Griggs, Edward J. Wing, J. Gregory Fitz.
    Introduction to molecular medicine -- Cardiovascular disease -- Pulmonary and critical care medicine -- Preoperative and postoperative care -- Renal disease -- Gastrointestinal disease -- Diseases of the liver and biliary system -- Hematologic disease -- Oncologic disease -- Endocrine disease and metabolic disease -- Women's health -- Men's health -- Diseases of bone and bone mineral metabolism -- Musculoskeletal and connective tissue disease -- Infectious disease -- Neurologic disease -- Geriatrics -- Palliative care -- Alcohol and substance abuse.
  • 2018From: ClinicalKey
    William D. James, Dirk M. Elston, Patrick J. McMahon.
    Structure and function -- Cutaneous signs and diagnosis -- Dermatoses resulting from physical factors -- Pruritus and neurocutaneous diseases -- Atopic dermatitis, eczema, and noninfectious immunodeficiency disorders -- Contact dermatitis and drug eruptions -- Erythema and urticaria -- Connective tissue diseases -- Mucinoses -- Seborrheic dermatitis, psoriasis, recalcitrant palmoplantar eruptions, pustular dermatitis, and erythroderma -- Pityriasis rosea, pityriasis rubra pilaris, and other papulosquamous and hyperkeratotic diseases -- Lichen planus and related conditions -- Acne -- Bacterial infections -- Diseases resulting from fungi and yeasts -- Mycobacterial diseases -- Hansen disease -- Syphilis, yaws, bejel, and pinta -- Viral diseases -- Parasitic infestations, stings, and bites -- Chronic blistering dermatoses -- Nutritional diseases -- Diseases of subcutaneous fat -- Endocrine diseases -- Abnormalities of dermal fibrous and elastic tissue -- Errors in metabolism -- Genodermatoses and congenital anomalies -- Dermal and subcutaneous tumors -- Epidermal nevi, neoplasms, and cysts -- Melanocytic nevi and neoplasms -- Macrophage/monocyte disorders -- Cutaneous lymphoid hyperplasia, cutaneous t-cell lymphoma, other malignant lymphomas, and allied diseases -- Diseases of skin appendages -- Diseases of mucous membranes -- Cutaneous vascular diseases -- Disturbances of pigmentation.
  • 2016From: ClinicalKey
    William D. James, Timothy G. Berger, Dirk M. Elston.
    1. Skin : basic structure and function -- 2. Cutaneous signs and diagnosis -- 3. Dermatoses resulting from physical factors -- 4. Pruritus and neurocutaneous dermatoses -- 5. Atopic dermatitis, eczema, and noninfectious immunodeficiency disorders -- 6. Contact dermatitis and drug eruptions -- Erythema and urticaria -- 7. Connective tissue diseases -- 8. Mucinoses -- 9. Seborrheic dermatitis, psoriasis, recalcitrant palmoplantar eruptions, pustular dermatitis, and erythroderma -- 11. Pityriasis rosea, pityriasis rubra pilaris, and other papulosquamous and hyperkeratotic diseases -- 12. Lichen planus and related conditions -- 13. Acne -- 14. Bacterial infections -- 15. Diseases resulting from fungi and yeasts -- 16. Mycobacterial diseases -- 17. Hansen's disease -- 18. Syphilis, yaws, bejel, and pinta -- 19. Viral diseases -- 20. Parasitic infestations, stings, and bites -- 21. Chronic blistering dermatoses -- 22. Nutritional diseases -- 23. Diseases of subcutaneous fat -- 24. Endocrine diseases -- 25. Abnormalities of dermal fibrous and elastic tissue -- 26. Errors in metabolism -- 27. Genodermatoses and congenital anomalies -- 28. Dermal and subcutaneous tumors -- 29. Epidermal nevi, neoplasms, and cysts -- 30. Melanocytic nevi and neoplasms -- 31. Macrophage/monocyte disorders -- 32. Cutaneous lymphoid hyperplasia, cutaneous t-cell lymphoma, other malignant lymphomas, and allied diseases -- 33. Diseases of the skin appendages -- 34. Disorders of the mucous membranes -- 35. Cutaneous vascular diseases -- 36. Disturbances of pigmentation -- 37. Dermatologic surgery -- 38. Cutaneous laser surgery -- 39. Cosmetic dermatology.
  • 2011From: Springer Protocols
    edited by Fahri Saatcioglu.
    Section I : Reviews -- 1. Molecular mechanisms of androgen action : A historical perspective / Albert O. Brinkmann -- 2. Androgen action during prostate carcinogenesis / Diping Wang and Donald J. Tindall -- Section II : Analysis of androgens -- 3. Androgen quantitation in prostate cancer tissue using liquid chromatography tandem mass spectrometry / Mark Titus and Kenneth B. Tomer -- 4. Ligand competition binding assay for the androgen receptor / Clémentine Féau [and others] -- Section III : Androgen receptor biology -- 5. Analysis of androgen receptor activity by reporter gene assays / Harri Makkonen [and others] -- 6. Identification and characterization of androgen response elements / Reinhilde de Bruyn, Rita Bollen, and Frank Claessens -- 7. In vitro and in vivo silencing of the androgen receptor / Helen Cheng, Eric Leblanc, and Paul S. Rennie -- 8. Analysis of interdomain interactions of the androgen receptor / Elizabeth M. Wilson -- 9. Methods to study dynamic interaction of androgen receptor with chromatin in living cells / Hatice Zeynep Kirli and Fahri Saatcioglu -- 10. FRET analysis of androgen receptor structure and biochemistry In living cells / Fred Schaufele -- Section IV : Analysis of androgen receptor modifications and interactions -- 11. Analysis of nuclear receptor acetylation / Chenguang Wang [and others] -- 12. Analysis of androgen receptor SUMOylation / Miia M. Rytinki [and others] -- 13. Analysis of ligand-specific co-repressor binding to the androgen receptor / Claudia Gerlach, Daniela Roell, and Aria Baniahmad --14. Detection of ligand-selective interactions of the human androgen receptor by SELDI-MS-TOF / Thomas Linke, Martin Scholten, and Aria Baniahmad -- Section V : Recent advances in studying androgen receptor signaling --15. Global identification of androgen response elements / Charles E. Massie and Ian G. Mills --16. Tissue-specific knockout of androgen receptor in mice / Tzu-hua Lin, Shuyuan Yeh, and Chawnshang Chang -- 17. Methodology to investigate androgen-sensitive and castration resistant human prostate cancer xenografts in preclinical setting / Holly M. Nguyen and Eva Corey -- 18. Automated microscopy and image analysis for androgen receptor function / Sean M. Hartig [and others] -- Section VI : Cross-talk of androgen and other signalling pathways -- 19. Androgen regulation of ETS gene fusion transcripts in prostate cancer / Delila Basi and Jan Trapman -- 20. Regulation of apoptosis by androgens in prostate cancer cells / Yke Jildouw Arnoldussen, Ling Wang, and Fahri Saatcioglu -- 21. Analysis of androgen receptor rapid actions in cellular signaling pathways : receptor/src association / Antimo Migliaccio, Gabriella Castoria, and Ferdinando Auricchio -- 22. Analysis of androgen-induced increase in lipid accumulation in prostate cancer cells / Jorgen Sikkeland, Torstein Lindstad, and Fahri Saatcioglu.
  • 2009From: Springer
    Donald Tindall, James Mohler, editors.
    Androgen action and modulation of prostate and prostate cancer growth : an historical perspective / Shutsung Liao ... [et al.] -- Clinical progression to castration-recurrent prostate cancer / Mark Pomerantz and Philip Kantoff -- Differential roles of androgen receptor in prostate development and cancer progression / Shuyuan Yeh ... [et al.] -- Imaging androgen receptor function in vivo / Michael Carey and Lily Wu -- Increased expression of genes converting adrenal androgens to testosterone in castration-recurrent prostate cancer / Steven P. Balk -- Androgen-metabolic genes in prostate cancer predisposition and progression / Juergen K.V. Reichardt and Ann W. Hsing -- Effect of steroid 5[alpha]-reductase inhibitors on markers of tumor regression and proliferation in prostate cancer / Lynn N. Thomas and Roger S. Rittmaster -- 5[alpha]-reductase isozymes in castration-recurrent prostate cancer / Mark A. Titus and James L. Mohler -- Improving intermittent androgen-deprivation therapy : OFF cycle and the role of steroid 5[alpha]-reductase inhibitors / Shubham Gupta, Daniel Shevrin, and Zhou Wang -- Insights from AR gene mutations / Grant Buchanan ... [et al.] -- Functional motifs of the androgen receptor / Elizabeth M. Wilson -- The role of the androgen receptor polyglutamine tract in prostate cancer : in mice and men / Diane M. Robbins -- The androgen receptor coactivator-binding interface / Eva Estébanez-Perpiñá and Robert J. Fletterick -- Co-regulators and the regulation of androgen receptor action in prostate cancer / Irina U. Agoulnik and Nancy L. Weigel -- Androgen receptor coregulators and their role in prostate cancer / Latif A. Wafa, Robert Snoek, and Paul S. Rennie -- Interaction of the androgen receptor ligand-binding domain with the n-terminal domain and with coactivators / Jan Trapman -- Multitasking and interplay between the androgen receptor domains / F.Claessens, T. Tanner, and A. Haelens -- Chromatin remodeling and androgen receptor-mediated transcription / Li Jia ... [et al.] -- Ligand-independent androgen receptor activity / Scott M. Dehm and Donald J. Tindall -- Role of IL-6 in regulating the androgen receptor / Zoran Culig and Alfred Hobisch -- The role of cyclic AMP in regulating the androgen receptor / Marianne D. Sadar -- Cellular and molecular signatures of androgen ablation of prostate cancer / Clifford G. Tepper and Hsing-Jien Kung -- Tissue levels of androgens in castration-recurrent prostate cancer / James L. Mohler and Mark A. Titus -- Unique effects of wnt signaling on prostate cancer cells : modulation of the androgen signaling pathway by interactions of the androgen receptor gene and protein with key components of the canonical wnt signaling pathway / Matthew J. Tanner ... [et al.] -- The role of foxa proteins in the regulation of androgen receptor activity / David J. DeGraff ... [et al.] -- Androgen receptor as a licensing factor for DNA replication / Donald J. Vander Griend and John T. Isaacs -- Androgen-regulated genes in the prostate / Nigel Clegg and Peter S. Nelson -- Mapping the androgen receptor cistrome / Qianben Wang and Myles Brown -- Differential regulation of clusterin isoforms by the androgen receptor Tanya K. Day, Colleen C. Nelson, and Martin E. Gleave -- Androgen regulation of prostate cancer gene fusions / Rou Wang, Scott A. Tomlins, and Arul M. Chinnaiyan -- Androgens and the lipogenic switch in prostate cancer / Johannes V. Swinnen ... [et al.] -- Molecular biology of novel targets identified through study of castration-recurrent prostate cancer / Philip A. Watson and Charles L. Sawyers -- Selenium and androgen receptor in prostate cancer / Nagalakshmi Nadiminty and Allen C. Gao.
  • 2013From: Springer
    Wayne J.G. Hellstrom, editor.
    1. The Institute of Medicine White Paper on Testosterone: Current Perspective / Craig F. Donatucci -- 2. The Laboratory Diagnosis of Testosterone Deficiency / Akanksha Mehta and Darius A. Paduch -- 3. The Clinical Diagnosis of Androgen Deficiency / Gregory C. Mitchell, Ege Can Serefoglu, and Wayne J.G. Hellstrom -- 4. The Use of Patient Reported Outcome Questionnaires in the Diagnosis of Androgen Deficiency / Gregory J. Lowe, George C. Bailey, and Tracey L. Krupski -- 5. Testosterone and Its Association with Metabolic and Cardiovascular Disease / Giovanni Corona, Giulia Rastrelli, and Mario Maggi -- 6. The Role of Androgens in Prostate Cancer / Frances Alba, Claudio A. Romero, and Run Wang -- 7. Androgen Deficiency in the Adolescent Male / Erin R. McNamara and Sherry S. Ross -- 8. Effects of Androgen Deficiency and Replacement on Male Fertility / Andrew C. Kramer -- 9. HIV and Testosterone in Men / Gina Cambareri, Jane Ashby, David Goldmeier, and Hossein Sadeghi-Nejad -- 10. Treatment Options for Testosterone Replacement Therapy / Mohit Khera -- 11. Alternate Therapies for Testosterone Replacement / Ege Can Serefoglu, Ahmet Gokce, Wayne J.G. Hellstrom, and André T. Guay.
  • 2006From: Springer
    edited by Ricardo Azziz, John E. Nestler, Didier Dewailly.
    A brief history of androgen excess / Ricardo Azziz -- Ovarian and adrenal androgen biosynthesis and metabolism / Walter L. Miller, David H. Geller, and Mitchell Rosen -- Androgens throughout the life of women / C. Richard Parker, Jr. -- Physiological effects of androgens in women / T. Keta Hodgson and Glenn D. Braunstein -- Androgen measurements: methods, interpretation, and limitations / Frank Z. Stanczyk -- Androgen-secreting adrenal and ovarian neoplasms / Michel Pugeat ... [et al.] -- Cushing's syndrome, acromegaly, and androgen excess / Anne-Céline Reyss and Didier Dewailly -- The nonclassic adrenal hyperplasias / Didier Dewailly and Ricardo Azziz -- Pregnancy-related androgen excess / Howard D. McClamrock -- Drug-induced hyperandrogenism / Barbara Neraud and Didier Dewailly -- Severe insulin-resistant hyperandrogenic syndromes / David E. Moller, Antonio Vidal-Puig, and Ricardo Azziz -- Idiopathic hirutism / Enrico Carmina -- Definition and epidemiology of the polycystic ovary syndrome / Ricardo Azziz -- Clinical features of the polycystic ovary syndrome / Walter Futterweit, Evanthia Diamanti-Kandarakis, and Ricardo Azziz -- Biochemical features of the polycystic ovary syndrome / Adam H. Balen -- Ovarian histology, morphology, and ultrasonography in the polycystic ovary syndrome / Sophie Jonard ... [et al.] -- Hypothalamic-pituitary-gonadtrophic dysfunction in the polycystic ovary syndrome / R. Jeffrey Chang and Rinku V. Mehta -- Ovarian steroidogenic abnormalities in the polycystic ovary syndrome / Denis A. Magoffin -- Hypothalamic-pituitary-adrenal dysfunction in the polycystic ovary syndrome / Bulent O. Yildiz, Enrico Carmina, and Ricardo Azziz -- The genetic basis of the polycystic ovary syndrome / Mark O. Goodarzi -- Pediatric hyperandrogenism and the polycystic ovary syndrome in adolescence / Kathleen M. Hoeger -- Environmental factors in the polycystic ovary syndrome / Marie-France Hivert and Jean-Patrice Baillargeon -- Animal models and fetal programming of the polycystic ovary syndrome / David H. Abbott ... [et al.] -- Insulin resistance and hyperinsulinism in the polycystic ovary syndrome / Paulina A. Essah and John E. Nestler -- The endocrine impact of obesity and body habitus in the polycystic ovary syndrome / Renato Pasquali and Alessandra Gambineri -- Molecular mechanisms of insulin resistance in the polycystic ovary syndrome / Theodore P. Ciaraldi -- Menstrual dysfunction and endometrial neoplasia in the polycystic ovary syndrome / Abdulkadir Wagley and Paul Hardiman -- Beta-cell dysfunction, glucose intolerance, and diabetes in the polycystic ovary syndrome / David A. Ehrmann -- Hypertension and cardiovascular and lipoprotein abnormalities in the polycystic ovary syndrome / Francesco Orio and Stefano Palomba -- Reproductive and obstetrical consequences of the polycystic ovary syndrome / Mary C. Johnson and Richard S. Legro -- Psychosocial and quality-of-life consequences of androgen excess and the polycystic ovary syndrome / Onno E. Janssen, Susanne Hahn, and Sigrid Elsenbruch -- Overview of long-term morbidity and economic cost of the polycystic ovary syndrome / Ricardo Azziz -- Clinical and hormonal evaluation of androgen excess / Ricardo Azziz -- Ovarian suppression and treatment of hirsutism / Paolo Moghetti -- Polycystic ovary syndrome and ovulation induction / Bulent O. Yildiz and Ricardo Azziz -- In vitro fertilization for the polycystic ovary syndrome / Hanadi Ba-Akdah ... [et al.] -- Surgical management of the polycystic ovary syndrome / Adam H. Balen -- Use of insulin sensitizers in the polycystic ovary syndrome / Kai I. Cheang and John E. Nestler -- Weight reduction and lifestyle modification in the treatment of androgen excess / Manny Noakes ... [et al.].
    Also available: Print – 2006
  • 2013From: Springer
    Zhou Wang, editor.
    Recent studies demonstrated a key role of the androgen receptor in the development of castration-recurrent or -resistant prostate cancer (CRPC), which is deadly and in urgent need of more effective therapies. Understanding the functions of androgen-responsive genes and their regulation and deregulation in prostate cancer progression may lead to new approaches to prevent and treat prostate cancer patients. This book provides an up-to-date review of the overall androgen-responsive gene expression program and the regulation, function, and clinical relevance of both protein coding and non-coding androgen-responsive genes. Experts in the field of androgen action and prostate cancer research discussed the importance of DNA elements, chromatin structure, cellular signaling, and cell-cell interactions in the regulation of androgen-responsive genes in the context of prostate cancer progression, including the development of CRPC. This book is intended for individuals interested in cancer endocrinology and medical and healthcare professionals involved in prostate cancer research.
  • 2015From: Cambridge
    edited by Leo Plouffe Jr., MD, CM, FACOG, FRCS(C), Vice President, Global Phamacovigilance, and Head, Risk Management, Bayer HealthCare Pharmaceuticals, Whippany, NJ, USA, Botros R.M.B. Rizk, MD, MA, FRCOG, FRCS, HCLD, FACOG, FACS, Professor of Obstetrics and Gynecology, and Director of the Division of Reproductive Endocrinology and Infertility, University of South Alabama, Mobile, AL, USA.
    Hirsutism : managing the basics / Héctor F. Escobar-Morreale -- Alopecia : managing the basics / Thamer Mubki and Jerry Shapiro -- Polycystic ovary syndrome : managing the basics / Keith Hansen -- Sexual dysfunction, including hypoactive sexual desire disorder : diagnosis and treatment recommendations / Ricki Pollycove and James Simon -- The androgen receptor : basic structure and function / Leo Plouffe -- Androgens in postmenopausal women : their intracrine formation and inactivation in peripheral tissues / Fernand Labrie -- Diagnostic criteria of polycystic ovary syndrome / Heather R. Burks and Robert A. Wild -- Androgen effects on the skin / Grace E. Kim and Alex B. Kimball -- Polycystic ovary syndrome and cardiovascular risk / Robert A. Wild -- Effects of androgens on female genital tract / Abdulmaged M. Traish and Andre T. Guay -- Congenital adrenal hyperplasia in females / Candice P. Holliday, Botros Rizk -- Cushing syndrome in females / Christopher B. Rizk, Andrew S. Fisher, and Sylvia Hsu -- Androgen-producing ovarian tumors / Patricia Carney -- Cognitive and behavioral impact of androgen disorders in females : learning from complete androgen insensitivity syndrome and congenital adrenal hyperplasia / Amy B. Wisniewski -- Testosterone replacement in aging male : lessons learned from the Women's Health Initiative / David Muram and Craig F. Donatucci -- History and physical examination polycystic ovary syndrome : detecting too much or too little / John J. Kohorst, Andrew S. Fischer, and Christopher B. Rizk -- Androgen assays : of mice and men / Keith A. Hansen -- Magnetic resonance imaging of the adrenal gland / Sajal S. Pokharel and Ihab R. Kamel -- Androgens and DHEA in postmenopausal medicine / Lila E. Nachtigall and Jeffrey A. Goldstein -- Lifestyle, diet and exercise in polycystic ovarian syndrome / Elizabeth Burt and Rina Agrawal -- Polycystic ovarian syndrome ovulation induction / Carolyn Alexander -- Ovulation induction in women with polycystic ovarian syndrome / Shawky Z.A. Badawy and Botros Rizk.
  • 2010From: Springer
    Eberhard Nieschlag, Hermann M. Behre, Susan Nieschlag (editors).
    1. Scope and goals of andrology / Eberhard Nieschlag -- 2. Physiology of testicular function / Gerhard F. Weinbauer ... [et al.] -- 3. Physiology of sperm maturation and fertilization / Trevor G. Cooper and Ching-Hei Yeung -- 4. Classification of andrological disorders / Frank Tüttelmann and Eberhard Nieschlag -- 5. Anamnesis and physical examination / Eberhard Nieschlag and Hermann M. Behre -- 6. Imaging diagnostics / Hermann M. Behre and Michael Zitzmann -- 7. Endocrine laboratory diagnosis / Manuela Simoni and Eberhard Nieschlag -- 8. Cytogenetic and molecular genetic investigations / Manuela Simoni and Peter Wieacker -- 9. Semen analysis / Trevor G. Cooper -- 10. Sperm quality and function tests / Ching-Hei Yeung and Trevor G. Cooper -- 11. Testicular biopsy and histology / Martin Bergmann and Sabine Kliesch -- 12. Diseases of the hypothalamus and the pituitary gland / Hermann M. Behre ... [et al.] -- 13. Disorders at the testicular level / Eberhard Nieschlag ... [et al.] -- 14. The aging male and late-onset hypogonadism / Claus Rolf, Michael Zitzmann, and Eberhard Nieschlag -- 15. Diseases of the seminal ducts / Hermann M. Behre ... [et al.] -- 16. Disorders of erection, cohabitation, and ejaculation / Hermann van Ahlen and Sabine Kliesch -- 17. Disorders of androgen target organs / Peter F. Wieacker, Hermann M. Behre, and Eberhard Nieschlag -- 18. Testicular dysfunction in systemic diseases / Gideon A. Sartorius and David J. Handelsman -- 19. Environmental influences on male reproductive health / Martin H. Brinkworth and David J. Handelsman -- 20. Gynecology relevant to andrology / Ulrich A. Knuth -- 21. Testosterone therapy / Eberhard Nieschlag and Hermann M. Behre -- 22. Empirical therapies for idiopathic male infertility / Eberhard Nieschlag and Axel Kamischke -- 23. Assisted reproduction / Christian De Geyter, Maria De Geyter, and Hermann M. Behre -- 24. Cryopreservation of human spermatozoa / Sabine Kliesch ... [et al.] -- 25. Psychology of fertility disorders / Regina Oberpenning, Fritz A. Muthny, and Frank Oberpenning -- 26. Sexual medicine and andrology / Klaus M. Beier -- 27. Male contribution to contraception / Eberhard Nieschlag -- 28. Vasectomy and refertilization / Udo H. Engelmann and Oliver Gralla -- 29. Approaches to hormonal male contraception / Eberhard Nieschlag and Hermann M. Behre -- 30. Pharmacological approaches to male contraception / Trevor G. Cooper and Ching-Hei Yeung -- 31. Ethical aspects of reproductive medicine / Klaus Demmer.
  • 2006From: Springer
    W.-B. Schill, F.H. Comhaire, T.B. Hargreave (eds.).
    Also available: Print – 2006
  • 2007From: Springer
    edited by Lodovico Balducci, William B. Ershler, John M. Bennett.
  • 2011From: Springer
    edited by Kathirvel Subramaniam, Kyung W. Park, Balachundhar Subramaniam.
    Applied anatomy of the aorta -- Acute aortic syndrome -- Preoperative cardiac evaluation before aortic surgery -- Role of echocardiography in aortic surgery -- Operative techniques in surgery of the proximal thoracic aorta and aortic arch -- Anesthesia for surgery of the ascending aorta and aortic arch -- Deep hypothermic circulatory arrest -- Cerebral monitoring during aortic surgery -- Understanding open repair of the descending thoracic and thoracoabdominal aorta -- Anesthesia for descending aortic surgery -- Spinal cord protection strategies -- Understanding endovascular aortic surgery: Endovascular repair of aortic aneurysmal disease -- Anesthesia for endovascular aortic surgery -- Anesthesia for open abdominal aortic aneurysm repair -- Renal protection strategies -- Comprehansive management of patients with traumatic aortic injury -- Anesthesia for adult congenital aortic surgery -- Atherosclerosis of the aorta and prevention of neurological dysfunction after cardiac surgery -- Postoperative care after aortic surgery.
  • 2014From: Cambridge
    edited by Ian McConachie, MB, ChB, FRCA, FRCPC, Associate Professor, Department of Anesthesia & Perioperative Medicine, Western University, London, Ontario, Canada.
    Risk and risk assessment -- Perioperative mortality and cardiac arrest -- Assessment of cardiovascular disease -- Cardiopulmonary exercise testing -- Perioperative cardiovascular medication management -- Perioperative optimization -- Respiratory risk and assessment -- Anemia, blood transfusion, and coagulopathy -- Diabetes -- The Obese or thin patient -- Obstructive sleep apnea and obesity hypoventilation syndrome -- Smoking, alcohol, and recreational drug abuse -- Intraoperative ventilatory management -- Analgesia for the high-risk patient -- Regional anesthesia for the high-risk patient -- Postoperative deterioration -- Acute kidney injury in surgical patients -- The Role of simulation in managing the high-risk patient -- Anesthesia, surgery, and palliative care -- The High-risk or critically ill patient in the operating room -- The Elderly patient -- The Patient with cardiac disease undergoing non-cardiac surgery -- Vascular surgery -- Gastrointestinal surgery -- Anesthesia and cancer surgery -- Neurotrauma and other high-risk neurosurgical cases -- Anesthesia for end-stage renal and liver disease -- Transplant patients.
  • 2013From: Wiley
    [edited by] Yehuda Ginosar, Felicity Reynolds, Stephen Halpern, Carl P. Weiner.
    Section 1: Basic Principles. Intrauterine Growth and Development / Timothy J M Moss, Cheryl A Albuquerque, Richard Harding -- Maternal Physiological Adaptations to Pregnancy / Julie Phillips, Melissa Covington, George Osol -- Placental Respiratory Gas Exchange / Lowell Davis -- The Fetal Circulation / Loren P Thompson, Kazumasa Hashimoto -- Fetal Responses to Hypoxia / Tania L Kasdaglis, Ahmet A Baschat -- Pharmacokinetics in Pregnancy / Janine R Hutson, Chagit Klieger, Gideon Koren -- The First Few Breaths: Normal Transition from Intra- to Extra-Uterine Life / Smadar Eventov-Friedman, Benjamin Bar-Oz -- Section 2: Endpoint Variables: Assessments of Fetal Wellbeing and Neonatal Outcome. Validity of Endpoint Measurement / Pamela J Angle, Stephen Halpern, Marcos Silva Restrepo, Alexander J Kiss -- Imaging of the Fetus and the Uteroplacental Blood Supply: Ultrasound / Kypros Nicolaides -- Imaging of the Fetus and the Uteroplacental Blood Supply: MRI / Caroline Wright, Philip Baker -- Fetal Heart Rate Monitoring / Alison M Premo, Sarah J Kilpatrick -- Fetal Acid-Base Monitoring / Lennart Nordstrom -- Fetal Pulse Oximetry / Paul B Colditz, Christine East -- Neonatal Assessment and Prediction of Neonatal Outcome / Vadivelam Murthy, Anne Greenough -- Section 3: Interventions: Anesthesia, Analgesia, and their Effects on the Fetus. Environmental Exposure to Anesthetic Agents / Asher Ornoy -- Anesthesia and Analgesia for Assisted Reproduction Techniques and other Procedures during the First Trimester / Arvind Palanisamy, Lawrence C Tsen -- The Effect of Anesthetic Drugs on the Developing Fetus: Considerations in Non-Obstetric Surgery / Richard S Gist, Yaakov Beilin -- Substance Abuse and Pregnancy / Donald H Penning, Allison J Lee -- Intrauterine Fetal Procedures for Congenital Anomalies / Amar Nijagal, Hanmin Lee, Mark Rosen -- The EXIT procedure / Sheldon M Stohl, Hindi E Stohl, Ari Y Weintraub, Kha M Tran -- Mechanisms and Consequences of Anesthetic-Induced Neuroapoptosis in the Developing Brain / Zhaowei Zhou, Adam P Januszewski, Mervyn Maze, Daqing Ma -- Relevance to Clinical Anesthesia of Anesthetic-Induced Neurotoxicity in Developing Animals / Catherine E Creeley, Mervyn Maze, John W Olney -- External Cephalic Version / Carolyn F Weiniger, Yossef Ezra -- Effects on the Fetus of General Versus Regional Anesthesia / Sharon Orbach-Zinger, Yehuda Ginosar -- Anesthesia for Cesarean Delivery: Effects on the Fetus of Maternal Blood Pressure Control / Warwick D Ngan Kee -- Effects on the Fetus of Maternal Oxygen Administration / Neeti Sadana, Scott Segal -- Effects on the Fetus of Maternal Position During Cesarean Delivery / Robin Russell -- Effects on the Fetus of Systemic vs. neuraxial analgesia / Stephen H Halpern, Marcos Silva Restrepo -- The Effects on the Fetus of Early Versus Late Regional Analgesia / Cynthia A Wong -- Regional Analgesia, Maternal Fever, and its Effect on the Fetus and Neonate / Tabitha A Tanqueray, Philip J Steer, Steve M Yentis -- Effects on the Fetus of Major Maternal Anesthetic Complications / Felicity Plaat, Ruth Bedson -- Section 4: Confounding Variables: The Compromised Fetus, the Compromised Mother. Multiple Pregnancy / Yehuda Habaz, Jon Barrett, Eric S Shinwell -- Preeclampsia: The Compromised Fetus, the Compromised Mother / Todd R Lovgren, Henry L Galan -- Fetal Distress / Robert A Dyer, Leann K Schoeman -- Section 5: Trauma and Resuscitation. Maternal Trauma / Yuval Meroz, Uriel Elchalal, Avraham I Rivkind -- Maternal Resuscitation and Perimortem Cesarean Delivery / Sharon Einav, Sorina Grisaru-Granovsky, Joseph Varon -- Intrauterine Fetal Resuscitation / Stephen Michael Kinsella, Andrew Shennan -- Neonatal Resuscitation and Immediate Neonatal Emergencies / Ritu Chitkara, Anand K Rajani, Louis P Halamek -- Section 6: Medicine, Ethics, and the Law. Fetal Beneficence and Maternal Autonomy: Ethics and the Law / William J Sullivan, Joanne Douglas -- Maternal-Fetal Research in Pregnancy / Frank A Chervenak, Laurence B McCullough.
  • 2012From: ScienceDirect
    2012From: ClinicalKey
    editred by Lee A. Fleisher.
    Eye, ear, nose, and throat diseases -- Cardiac diseases -- Congenital heart disease -- Respiratory diseases -- Liver diseases -- Obesity and nutrition disorders -- Renal diseases -- Neurological diseases -- Muscle diseases -- Skin and bone disorders -- Hematologic diseases -- Infectious diseases and biologic weapons -- Diseases of the endocrine system -- Mitochondrial Disease -- Psychiatric and behavioral disorders -- Mineral, vitamin, and herbal supplements -- Trauma and acute care -- Burns -- Pregnancy and obstetric complications -- Geriatric patient -- Pediatric patient.
  • 2013From: ClinicalKey
    [edited by] Jan Ehrenwerth, James B. Eisenkraft, James M. Berry.
    1. Medical gases: storage and supply -- 2. The Anesthesia machine and workstation -- 3. Anesthesia vaporizers -- 4. Breathing circuits -- 5. Waste anesthetic gases and scavenging systems -- 6. Anesthesia ventilators -- 7. Humidification and filtration - 8. Respiratory gas monitoring -- 9. Monitoring ventilation -- 10. Capnography -- 11. Pulse oximetry -- 12. Blood pressure monitoring -- 13. Electrocardiographic monitoring -- 14. Temperature monitoring -- 15. Monitoring neuromuscular blockade -- 16. Airway equipment -- 17. Pediatric anesthesia systems and equipment -- 18. Infusion pumps -- 19. Noninvasive temporary pacemakers and defibrillators -- 20. Infection prevention: recommendations for practice -- 21. Computing and the Internet in clinical practice -- 22. Perioperative informatics -- 23. Vigilance, alarms, and integrated monitoring systems -- 24. Ergonomics of the anesthesia workspace -- 15. Simulation equipment, techniques, and applications -- 26. Closed-circuit anesthesia -- 27. Anesthesia delivery in the MRI environment -- 28. Anesthesia at high altitude -- 29. Anesthesia in difficult locations and in developing countries -- 30. Hazards of the anesthesia delivery system -- 31. Electrical and fire safety -- 32. Machine checkout and quality assurance -- 33. Risk management and medicolegal aspects of anesthesia equipment -- 34. Standards and regulatory considerations.
  • James A. DiNardo, David A. Zvara.
    PrintStatus: Not Checked OutLane Catalog Record
    Myocardial physiology and the interpretation of cardiac catheterization data -- Monitoring -- Anesthesia for myocardial revascularization -- Anesthesia for valvular heart disease -- Congenital heart disease -- Anesthesia for heart, heart-lung, and lung transplantation -- Pericardial disease -- Anesthesia for surgery of the thoracic aorta -- Management of cardiopulmonary bypass -- Mechanical circulatory support -- Myocardial preservation during cardiopulmonary bypass -- Special considerations during cardiac surgery.
  • 2007From: Ovid
    Victor C. Baum, Jennifer E. O'Flaherty.
  • 2015From: Ovid
    Victor C. Baum, Jennifer E. O'Flaherty.
  • 2013From: Cambridge
    edited by Basem Abdelmalak, D. John Doyle.
    Section 1. Introduction -- Section 2. Anesthesia for nasal, sinus and pituitary surgery -- Section 3. Anesthesia for head and neck surgery -- Section 4. Anesthesia for laryngotracheal surgery -- Section 5. Anesthesia for bronchoscopic surgery -- Section 6. Anesthesia for pediatric ENT surgery.
  • 2012From: Cambridge
    [edited by] Ehab Farag, M.D., F.R.C.A, Staff Anesthesiologist, Departments of General Anesthesia and Outcomes Research, Cleveland Clinic, Ohio, USA.
    The increased complexity of spinal surgical procedures in recent years has required more sophisticated anesthetic management of patients undergoing these procedures. Spine surgery anesthesia is now recognized as a distinct sub-specialty, increasingly undertaken by general anesthesiologists as well as neuroanesthesiologists. Ehab Farag describes the anesthetic management and surgical procedures at every vertebral level in both adult and pediatric patients. The most important related considerations are covered, including: Postoperative pain management. One lung ventilation during anterior thoracic spine surgery. Intraoperative neuromonitoring. Fluid management additional chapters review the radiological features of normal and abnormal spines, common complications of spine surgery and ASA closed claims relating to spine surgery anesthesia. Written by highly experienced neuroanesthesiologists and spine surgeons.
  • 2014From: Springer
    Corey S. Scher, editor.
    Anesthesia for Trauma is a comprehensive, clinically oriented text for practitioners and trainees in anesthesia, pain management, and critical care. It covers core topics, from initial assessment and blood and blood products, to the multi-trauma patient and trauma by major anatomical region. Burns receive especially extensive coverage. Special considerations when administering anesthesia to traumatically injured children, pregnant women, and older people are reviewed, as are foundational areas such as clinically relevant physiology and the growing role of trauma simulation in training. Readers will find leading edge coverage of microvascular surgery, pain management, and critical care of trauma patients as well as up-to-date chapters on trauma in the military, civilian trauma systems, and disaster management. The book concludes with a unique 'must-read' chapter for all clinicians on the link between substance abuse and penetrating trauma.
  • 2014From: Springer
    Daniel M. Gainsburg, Ethan O. Bryson, Elizabeth A. M. Frost, editors.
    This is an up-to-date clinical reference on anesthesia for urological surgery. Advances in urological procedures, the advent of treatment of patients with strong anticoagulant and antiplatelet medications, and the demographics of urology patients (many of whom are young or elderly) present challenges for the anesthesiologist and have necessitated changes in anesthesia practice. Urological anesthesia is not recognized as a subspecialty, and this book, which reflects the expertise of clinicians and researchers from around the United States and Europe, is written for the majority of anesthesiologists and nurse anesthetists who will provide anesthesia for these patients. The book includes coverage of these topics: Renal physiology and pharmacology Urologic anesthesia in all age groups, and in both the operating room and outpatient setting Special considerations in the pregnant patient and in renal transplantation Anesthesia for robotic surgery of the prostate In older patients, problems arising from co-morbidities and the risk of drug interactions Appropriate pain management in inpatient and outpatient settings The unique challenges of positioning the patient Medico-legal considerations, including analyses from the closed claims study
  • 2007From: Cambridge
    [edited by] Barry L. Friedberg.
    Propofol ketamine with bispectral index (BIS) monitoring / Barry L. Friedberg -- Preoperative instructions, intraoperative environment / Barry L. Friedberg -- Level-of-consciousness monitoring / Scott D. Kelley -- The dissociative effect and preemptive analgesia / Barry L. Friedberg -- Special needs of cosmetic dental patients / James A. Snyder -- Propofol Ketamine in the UK, Propofol Ketamine beyond cosmetic surgery / Chris Pollock -- Propofol Ketamine beyond cosmetic surgery : implications for military medicine and mass-casualty anesthesia / Joel W. McMasters -- Lidocaine use and toxicity in cosmetic surgery / Adam Frederic Dorin -- Local anesthetic blocks in head and neck surgery / Joseph Niamtu -- Local anesthetics and surgical considerations for body contouring / Roger Wade Pielet -- Intravenous anesthesia for cosmetic surgery / David Barinholtz -- Regional anesthesia for cosmetic surgery / Holly Evans and Susan M. Steele -- General inhalation anesthesia for cosmetic surgery / Meena Desai -- Preanesthetic assessment of the cosmetic surgery patient / Norman Levin -- Psychological aspects of cosmetic surgery / David B. Sarwer, Canice E. Crerand, and Lauren M. Gibbons -- The business of the office-based anesthesia for cosmetic surgery / Marc E. Koch -- The politics of office-based anesthesia / David Barinholtz -- Staying out of trouble : the medicolegal perspective / Ann Lofsky.
  • 2008From: Springer
    Jerry Stonemetz, Keith Ruskin, editors.
  • 2014From: Springer
    Fernando Alemanno, Mario Bosco, Aldo Barbati, editors.
    Loco-regional anesthesia presents definite advantages in almost all surgical branches, since it couples a perfect anesthesia with a long postoperative analgesia. This discipline is constantly developing thanks to new drugs and new techniques. In the last decade the advent of ultrasound guided regional anesthesia has extended the study from the anatomic room to the virtual but real "in corpore viri" ecographic image thus increasing the success rate of this type of anesthesia. Together with electrostimulation, it has definitely increased the success rate of loco-regional anesthesia. Nonetheless, though supported by new fundamental tools, it is of the utmost importance for anesthesiologists to have a deep knowledge of the brachial plexus and of the topographic anatomy, on which the two first chapters are focused. Featuring a total of 16 chapters and more than 140 color illustrations, the volume provides a detailed coverage of this technique, thus representing a very useful tool for specializing students as well anesthesiologists in their daily clinical practice.
  • 2011From: ProQuest Ebook Central
    [edited by] James Duke.
    Basics of Patient Management -- Pharmacology -- Preparing for Anesthesia -- Patient Monitoring and Procedures -- Perioperative Problems -- Anesthesia and Systemic Disease -- Special Anesthetic Considerations --Regional Anesthesia -- Anesthetic Considerations in Selected Surgical Procedures -- Pain Management.
    Also available: Print – 2011
  • 2016From: Springer
    Jesse M. Ehrenfeld, Richard D. Urman, Scott Segal, editors.
  • 2010From: Springer
    editors, Jesse M. Ehrenfeld, Richard D. Urman, Scott Segal.
  • 2014From: Ovid
    editor, Richard A. Jaffe ; associate editors, Clifford A. Schmiesing, Brenda Golianu.
    Neurosurgery -- Ophthalmic surgery -- Otolaryngology/head and neck surgery -- Dental surgery -- Thoracic surgery -- Cardiovascular surgery -- General surgery -- Obstetric/gynecologic surgery -- Urology -- Orthopedic surgery -- Plastic and reconstructive surgery -- Pediatric surgery -- Out-of-operating room procedures -- Office-based anesthesia -- Emergency procedures for the anesthesiologist.
  • editors, Richard A. Jaffe, Stanley I. Samuels ; associate editors, Clifford A. Schmiesing, Brenda Golianu.
    PrintStatus: Not Checked OutLane Catalog Record
  • edited by David E. Longnecker ... [et al.].
    PrintStatus: Not Checked OutLane Catalog Record
  • 2013From: Springer
    edited by Adam I. Levine, Satish Govindaraj, Samuel DeMaria, Jr.
    Working Side by Side: The Important Relationship Between Anesthesiologists and Otolaryngologists / Adam I. Levine, Samuel DeMaria Jr., Satish Govindaraj -- Gross and Radiographic Anatomy / Puneet Pawha, Nancy Jiang, Katya Shpilberg -- Basic Pharmacology of Anesthetic Agents / Wagdy Sidrak, Adam I. Levine, Samuel DeMaria Jr. -- Basic Physiology / Ira Hofer, Samuel DeMaria Jr., Adam I. Levine -- Physiologic Monitoring / Jaime B. Hyman, David L. Reich -- Oxygen Delivery Systems and the Anesthesia Workstation / James B. Eisenkraft, Robert Williams -- Preoperative Assessment and Optimization / Jaime B. Hyman, Andrew B. Leibowitz -- Airway Management, Emergencies and the Difficult Airway / Irene P. Osborn, Andrew J. Kleinberger -- Adult Sleep Apnea and Related Procedures / Menachem M. Weiner, Fred Y. Lin -- Phonomicrosurgery and Office-Based Laryngology / Allan P. Reed, Peak Woo -- Otologic Surgery / Cheryl K. Gooden -- Facial Plastic Surgery / Adam I. Levine, Samuel DeMaria Jr., Eunice Park -- Functional Nasal and Sinus Surgery / Alan J. Sim, Adam I. Levine, Satish Govindaraj -- Thyroid, Parathyroid, and Parotid Surgery / Steven Porter, Andrew Schwartz -- Head and Neck Cancer Surgery I: Resection / Adam I. Levine, Samuel DeMaria Jr. -- Head and Neck Cancer Surgery II: Reconstruction / Adam I. Levine, Samuel DeMaria Jr., Brett A. Miles -- Neurosurgical Otolaryngology I: Neurotology/Posterior Fossa Surgery / Jess W. Brallier, Eric E. Smouha -- Neurosurgical Otolarynology II: Endoscopic Skull Base and Pituitary Surgery / Stacie G. Deiner, Kalmon D. Post, Satish Govindaraj -- Tracheotomy / Sharmin Haque, Adam I. Levine, Chan W. Park -- Pediatric Otolaryngology / Jonathan S. Gal, Francine S. Yudkowitz -- Office-Based Otolaryngology / Laurence M. Hausman -- Acute and Chronic Pain Management / Yury Khelemsky -- Postoperative Care / Jody Jones, Brigid Flynn -- Medico-Legal Considerations and Patient Safety / Elizabeth A. M. Frost.
  • edited by Alex S. Evers, Mervyn Maze, Evan D. Kharasch.
    PrintStatus: Not Checked OutLane Catalog Record
    "In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, second edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period"--Provided by publisher.
  • Kristen Brooke Backor.
    This dissertation explored expression of anger in the workplace through two experiments that varied in terms of the gender of the person expressing the anger, the frequency of the anger, and the object of the anger. Subjects reviewed resumes and performance reviews that they were told belonged to two consultants competing for the same promotion. Consultants who were said to express anger frequently were less likely to be promoted than neutral consultants. They also suffered social consequences, like being rated as less pleasant. Consultants who expressed anger a single time suffered social consequences (albeit less severe than those experienced by the frequently angry individuals) compared to neutral consultants, but their promotional outcomes were less affected. When respondents were given the option to promote both the neutral consultant and the angry consultant, most subjects chose to do so. The Study 1 results were based on an undirected expression of anger; Study 2 respondents were told that the anger was directed at a subordinate. A single instance of directed anger was more damaging to social and promotional outcomes than a single instance of undirected anger. Few gender effects were observed in either study, and the gender effects that were observed tended to favor females.
  • 2008From: ScienceDirect
    edited by David Cheresh.
    Also available: Print – 2008
  • pt. A-B, 2008.From: ScienceDirect
    pt. BFrom: ScienceDirect
    editor, David A. Cheresh.
    Also available: Print – pt. A-B, 2008.
  • 2007From: Springer
    edited by William D. Figg and Judah Folkman.
  • 2007From: CRCnetBASE
    edited by Napoleone Ferrara.
  • 2008From: Springer
    Michael P. Seed, David A. Walsh, editors.
    Also available: Print – 2008
  • 2010From: Springer
    Rüdiger Liersch, Wolfgang E. Berdel, Torsten Kessler (eds.).
    Angiopoietins / Yvonne Reiss -- HIF-1 alpha and cancer therapy / Mei Yee Koh, Tally R. Spivak-Kroizman, Garth Powis -- Chemokines / Andreas Hippe, Bernhard Homey, Anja Meuller-Homey -- Angiogenesis inhibition in cancer therapy / Iris Appelmann ... [et al.] -- Vascular integrins : therapeutic and imaging targets of tumor angiogenesis / Curzio Ruegg, Gian Carlo Alghisi -- PDGF and vessel maturation / Carina Hellberg, Arne Ostman, C.-H. Heldin -- Lymphangiogenesis in cancer : current perspectives / Rudiger Liersch ... [et al.] -- Compounds in clinical phase III and beyond / Torsten Kessler ... [et al.] -- Metronomic chemotherapy : principles and lessons learned from applications in the treatment of metastatic prostate cancer / Urban Emmenegger ... [et al.] -- Targeting inflammatory cells to improve anti-VEGF therapies in oncology / Hans-Peter Gerber, Ezogelin Olazoglu, Iqbal S. Gerwal -- Antibody-based vascular tumor targeting / Christoph Schliemann, Dario Neri -- Caveolae and cancer / Kerri A. Massey, Jan E. Schnitzer.
  • 2014From: Karger
    volume editors: Gianni Marone, Francescopaolo Granata.
    History of research on angiogenesis -- Immune cells as a source and target of angiogenic and lymphangiogenic factors -- Neuropilins: role in signalling, angiogenesis and disease -- Class 3 semaphorin in angiogenesis and lymphangiogenesis -- Angiogenic and antiangiogenic chemokines -- Role of uPA/uPAR in the modulation of angiogenesis -- Neutrophil-derived cytokines involved in physiological and pathological angiogenesis -- Roles of eosinophils in the modulation of angiogenesis -- Regulatory T cells, leptin and angiogenesis -- Angiogenesis as a therapeutic target for obesity and metabolic diseases -- Angiogenesis in multiple myeloma -- Angiogenesis inhibitors in the treatment of prostate cancer -- Therapeutic perspectives in vascular remodeling in asthma and chronic obstructive pulmonary disease.
  • 2013From: Springer
    Shaker A. Mousa, Paul J. Davis, editors.
    This book is a major update of novel targets in angiogenesis modulation, including pro- and anti-angiogenesis. There is in-depth coverage of preclinical and clinical methods and models, investigational status, and clinical applications. The impact of nanotechnology in advancing the applications of pro-and anti-angiogenesis strategies is also highlighted, along with stem cell and biotechnologies in research and development of angiogenesis modulating targets.
  • 2004From: HighWire
    edited by S. Ylä-Herttuala, V.J. Dzau.
    Also available: Print – 2004
  • edited by Robert R. Ruffolo, Jr.
    PrintStatus: Not Checked OutLane Catalog Record
    v. 1. Molecular biology, biochemistry, pharmacology, and clinical perspectives -- v. 2. Medi cinal chemistry.
  • 2003From: HighWire
    Also available: Print – 2003
  • 2014From: Springer
    edited by Michael Ritsner.
    Conceptual Issues -- The Different Facets of Anhedonia and Their Associations with Different Psychopathologies -- Understanding Anhedonia: The Role of Perceived Control -- Circadian Fluctuation of Reward Response and Synchronization to Reward -- Anhedonia in Children and Adolescents -- Musical Anhedonia and Visual Hypoemotionality: Selective Loss of Emotional Experience in Music and Vision -- Projecting Oneself into the Future, an Intervention for Improving Pleasure in Patients with Anhedonia -- Neurobiological Advances -- Translational Models of Dopaminergic Mechanisms for Motivational Deficits in Anhedonic Patients -- Brain Systems for the Pleasure of Food and Other Primary Rewards -- Neurogenetics and Neurobiology of Dopamine in Anhedonia -- The Neuroendocrinology of Anhedonia -- Electrophysiological Signatures of Reward Processing in Anhedonia -- Anhedonia in Mouse Models of Methamphetamine-Induced Drug Seeking Behavior -- Neural Basis of Anhedonia Associated with Stress-Induced Eating Disorders -- Brain Imaging Correlates of Anhedonia.
  • 2014From: Springer
    edited by Michael Ritsner.
    Anhedonia in Psychotic Disorders -- Anhedonia in Schizophrenia: A Brief History and Overview of the Construct -- Measuring Anhedonia in Schizophrenia-Spectrum Disorders: A Selective Update -- Hedonic Capacity and Related Factors in Schizophrenia and Schizoaffective Disorder -- Anhedonia as an Indicator of Genetic Vulnerability to Schizophrenia -- Anhedonia in Schizophrenia: A Deficit in Translating Reward Information into Motivated Behavior -- Anhedonia in Mood and Personality Disorders -- Neural Correlates of Anhedonia as a Trait Marker for Depression -- Anhedonia in Trauma Related Disorders: The Good, the Bad, and the Shut-Down -- Anhedonia and Anorexia Nervosa: A Neurocognitive Perspective -- Anhedonia and Negative Symptom Schizotypy -- Anticipatory and Consummatory Anhedonia in Individuals with Schizotypal Traits -- Anhedonia and Risk of Suicide: An Overview -- Anhedonia in Neurological and Physical Disorders -- Anhedonia and Epilepsy -- Anhedonia in Parkinson's Disease and Other Movement Disorders -- Anhedonia in Heart Disease -- Cerebrovascular Diseases: Post-stroke Depression and Anhedonia.
  • 2001From: CRCnetBASE
    Edward M. Barrows.
  • 2014From: ScienceDirect
    edited by Ashish S. Verma, Anchal Singh.
    Animal Biotechnology introduces applications of animal biotechnology and implications for human health and welfare. It begins with an introduction to animal cell cultures and genome sequencing analysis and provides readers with a review of available cell and molecular tools. Topics here include the use of transgenic animal models, tissue engineering, nanobiotechnology, and proteomics. The book then delivers in-depth examples of applications in human health and prospects for the future, including cytogenetics and molecular genetics, xenografts, and treatment of HIV and cancers. All this is complemented by a discussion of the ethical and safety considerations in the field. Animal biotechnology is a broad field encompassing the polarities of fundamental and applied research, including molecular modeling, gene manipulation, development of diagnostics and vaccines, and manipulation of tissue. Given the tools that are currently available and the translational potential for these studies, animal biotechnology has become one of the most essential subjects for those studying life sciences. Highlights the latest biomedical applications of genetically modified and cloned animals with a focus on cancer and infectious diseases. Provides firsthand accounts of the use of biotechnology tools, including molecular markers, stem cells, and tissue engineering.
  • 2007From: Springer Protocols
    edited by Ralf Pörtner.
  • 2014From: Springer Protocols
    edited by Ralf Pörtner.
    High-throughput synchronization of mammalian cell cultures by spiral microfluidics / Wong Cheng Lee, Ali Asgar S. Bhagat, and Chwee Teck Lim -- Insect cell line development using Flp-mediated cassette exchange technology / João Vidigal ... [et al.] -- Scalable transient gene expression in adherent mammalian cells using polyethylenimine / Lukas Fliedl and Christian Kaisermayer -- Scalable transient protein expression / Henry C. Chiou ... [et al.] -- DNA profiling and characterization of animal cell lines / Glyn N. Stacey, Ed Byrne, and J. Ross Hawkins -- Tools for high-throughput process and medium optimization / Martin Jordan and Matthieu Stettler -- Designing media for animal cell culture : CHO cells, the industrial standard / Karlheinz Landauer -- Feed optimization in fed-batch culture / Ana Rita Costa ... [et al.] -- Screening and optimization of chemically defined media and feeds with integrated and statistical approaches / Zhihua Xiao ... [et al.] -- Evaluation of solid and porous microcarriers for cell growth and production of recombinant proteins / Maria Elisa Rodrigues ... [et al.] -- Microbioreactors and scale-down models : growth of CHO cells using the pall micro24 microreactor system / Steve R.C. Warr -- Monitoring cell growth, viability, and apoptosis / Michael Butler, Maureen Spearman, and Katrin Braasch -- Metabolic flux estimation in mammalian cell cultures / Chetan T. Goudar ... [et al.] -- Quenching methods for the analysis of intracellular metabolites / Judith Wahrheit and Elmar Heinzle -- NMR methods for metabolomics of mammalian cell culture bioreactors / Nelly Aranibar and Michael D. Reily -- 1H-NMR protocol for exometabolome analysis of cultured mammalian cells / Tiago M. Duarte ... [et al.] -- Microfluidic perfusion culture / Koji Hattori, Shinji Sugiura, and Toshiyuki Kanamori -- Disposable bioreactors for inoculum production and protein expression / Regine Eibl, Christian Löffelholz, and Dieter Eibl -- Configuration of bioreactors / Dirk E. Martens, Evert J.van den End, and Mathieu Streefland -- Process analytical technology (PAT) in insect and mammalian cell culture processes : dielectric spectroscopy and focused beam reflectance measurement (FBRM) / Damir Druzinec ... [et a.] -- Cell assessment by at-line microscopy / Alexander Babitzky, Patrick Lindner, and Thomas Scheper -- Seed train optimization for cell culture / Björn Frahm -- Vaccine production : upstream processing with adherent or suspension cell lines / Yvonne Genzel ... [et al.] -- Efficient processes for protein expression using recombinant baculovirus particles / Heike Cremer ... [et al.] -- Chromatographic techniques in the downstream processing of proteins in biotechnology / Ruth Freitag -- Virus separation using membranes / Tanja A. Grein, Ronald Michalsky, and Peter Czermak.
  • 2015From: Springer
    edited by Mohamed Al-Rubeai.
    Animal cells are the preferred "cell factories" for the production of complex molecules and antibodies for use as prophylactics, therapeutics or diagnostics. Animal cells are required for the correct post-translational processing (including glycosylation) of biopharmaceutical protein products. They are used for the production of viral vectors for gene therapy. Major targets for this therapy include cancer, HIV, arthritis, cardiovascular and CNS diseases and cystic fibrosis. Animal cells are used as in vitro substrates in pharmacological and toxicological studies. This book is designed to serve as a comprehensive review of animal cell culture, covering the current status of both research and applications. For the student or R&D scientist or new researcher the protocols are central to the performance of cell culture work, yet a broad understanding is essential for translation of laboratory findings into the industrial production. Within the broad scope of the book, each topic is reviewed authoritatively by experts in the field to produce state-of-the-art collection of current research. A major reference volume on cell culture research and how it impacts on production of biopharmaceutical proteins worldwide, the book is essential reading for everyone working in cell culture and is a℗lrecommended volume for all biotechnology libraries.
  • 2009From: Springer
    Koji Ikura [and others], editors.

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