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  • Advances in neuroendocrine tumor management / Kjell Öberg -- Classification of digestive neuroendocrine neoplasm / Guido Rindi & Frediano Inzani -- Molecular profile and diagnosis / Christos Toumpanakis -- Surgical approach / Rossella Bettini & Massimo Falconi -- Somatostatin analogs / Wouter W. de Herder -- Combinational chemotherapy and radiotherapy / Emilio Bajetta, Emilio Bombardieri, Laura Catena, Monica Valente & Nadia Bianco -- Which therapy for which patient? / Kjell Öberg.
  • Physical implementation of the memristor at industrial scale sparked the interest from various disciplines, ranging from physics, nanotechnology, electrical engineering, neuroscience, to intelligent robotics. As any promising new technology, it has raised hopes and questions; it is an extremely challenging task to live up to the high expectations and to devise revolutionary and feasible future applications for memristive devices. The possibility of gathering prominent scientists in the heart of the Silicon Valley given by the 2011 International Joint Conference on Neural Networks held in San Jose, CA, has offered us the unique opportunity of organizing a series of special events on the present status and future perspectives in neuromorphic memristor science. This book presents a selection of the remarkable contributions given by the leaders of the field and it may serve as inspiration and future reference to all researchers that want to explore the extraordinary possibilities given by this revolutionary concept.
  • This book comprises proceedings from the Third International Conference on Advances in Nutrition and Cancer, held in Naples in May 2012. This highly multidisciplinary meeting analyzed nutrition and cancer from different perspectives and on the basis of distinct and up-to-date experimental approaches. Knowledge on the relation between lifestyle, diet, and cancer is explored in a number of contributions, and the role of dietary intervention in cancer patients is discussed. Issues of vital interest to the research community, such as epidemiological and experimental oncology (genetics, epigenetics, and the mechanisms of action of natural compounds in the diet), receive detailed consideration. A further key topic is the emerging molecular technologies (the -omics) that can cast light on the interplay between nutrition and human malignancies. Chapters take the form of reviews that include sections presenting expert opinions. Advances in Nutrition and Cancer will be an invaluable source of topical information for all researchers and clinicians with an interest in this field.
  • Advances in ovarian cancer management / Peter E. Schwartz -- Etiology and overview / Gang Ye, Stefanie Bernaudo & Chun Peng -- Diagnostic imaging in the management of ovarian masses / Amit Mahajan, Indukala Doddamane & Shirley McCarthy -- Initial surgical management of ovarian cancer / Jason Knight & Peter G. Rose -- Initial chemotherapy for the treatment of ovarian cancer / Katherine M. Moxley & Robert S. Mannel -- Neoadjuvant chemotherapy in the management of advanced ovarian cancer / Peter E. Schwartz -- Intraperitoneal chemotherapy : its use in epithelial ovarian cancer / Neesha Dhani & Helen Mackay -- Chemotherapeutic management of recurrent ovarian cancer / Marcia Hall -- Emerging chemotherapy agents in ovarian cancer / Daliah Tsoref & Amit M. Oza -- Surgical management of recurrent ovarian cancer / Eelco de Bree -- Angiogenesis in ovarian cancer / Vincent Castonguay & Amit M. Oza -- Antigen-specific immunotherapy for ovarian cancer / Dana M. Roque & Alessandro D. Santin -- Poly(ADP-ribose) polymerase inhibitors and epithelial ovarian cancer -- Thomas P. McNally, Gillianne G.Y. Lai & Richard T. Penson -- Emerging targeted therapies / Mirko Marabese & Massimo Broggini -- Palliative care in ovarian cancer / Cynthia O'Sullivan, Elizabeth Ercolano & Ruth McCorkle -- Guidelines in ovarian cancer / Domenica Lorusso, Antonella Pietragalla & Giovanni Scambia -- Index.
  • Advances in pancreatic cancer treatment / Helmut Friess & Norbert Hüser -- Pathophysiology of pancreatic cancer / J. Matthias Löhr, Stephan L. Haas & Rainer Heuchel -- Molecular diagnostics in pancreatic cancer / David K. Chang, Sean M. Grimmond & Andrew V. Biankin -- Surgical therapy for pancreatic cancer / Norbert Hüser, Volker Assfalg & Helmut Friess -- Multimodal treatment concepts in pancreatic cancer / Daniel Reim, Alexander Novotny & Helmut Friess -- Consensus guidelines in pancreatic cancer treatment / Wasif Saif -- Drugs in clinical trials & future directions / Zhiqiang Huang & Donald J. Buchsbaum.
  • Management of Peritoneal Surface Malignancy: A Short History / Paul H. Sugarbaker -- The Natural History of Free Cancer Cells in the Peritoneal Cavity / Yutaka Yonemura, Taiichi Kawamura, Etsurou Bandou, Gorou Tsukiyama and Yoshio Endou, et al. -- Pathological Evaluation and Implications of Serosal Involvement in Gastrointestinal Cancer / Linmarie Ludeman and Neil A. Shepherd -- Principles of Perioperative Intraperitoneal Chemotherapy for Peritoneal Carcinomatosis / Eelco de Bree and Dimitris D. Tsiftsis -- Experimental and Pharmacokinetic Studies in Intraperitoneal Chemotherapy: From Laboratory Bench to Bedside / Eelco de Bree and Dimitris D. Tsiftsis -- Technology for the Delivery of Hyperthermic Intraoperative Intraperitoneal Chemotherapy: A Survey of Techniques / Amod A. Sarnaik, Jeffrey J. Sussman, Syed A. Ahmad, Benjamin C. McIntyre and Andrew M. Lowy -- Adjuvant Intraperitoneal Chemotherapy: A Review / Paul H. Sugarbaker -- Clinical Research Methodology in Peritoneal Surface Oncology: A Difficult Challenge / François-Noël Gilly, Olivier Glehen, Annie C. Beaujard and Eddy Cotte -- Lessons Learnt from Clinical Trials in Peritoneal Surface Oncology: Colorectal Carcinomatosis / Frans A. N. Zoetmulder and Vic J. Verwaa -- Experimental Models and Questions in Basic Science Research for Pseudomyxoma Peritonei / Laura A. Lambert, Donald H. Lambert and Paul Mansfield -- Peritoneal Carcinomatosis of Colorectal Origin: Recent Advances and Future Evolution Toward a Curative Treatment / Dominique Elias and Diane Goere -- Pathologic Characterization and Differential Diagnosis of Malignant Peritoneal Mesothelioma / Nelson G. Ordóñez -- Advances in Clinical Research and Management of Diffuse Peritoneal Mesothelioma / Marcello Deraco, Dario Baratti, Nadia Zaffaroni, Antonello Domenico Cabras and Shigeki Kusamura -- Advances in the Management of Gastric Cancer with Peritoneal Dissemination / Yutaka Yonemura, Taiichi Kawamura, Etsurou Bandou, Gorou Tsukiyama and Masayuki Nemoto, et al. -- Intraperitoneal Chemotherapy in the Management of Ovarian Cancer / Maurie Markman.
  • Personalized genomic medicine: is a cancer care revolution achievable? / Dimitrios H. Roukos -- Targeting the individual cancer patient / Georgios Baltogiannis, Christos S. Katsios & Dimitrios H. Roukos -- Biomarkers-guided targeted drugs: new clinical trials design and practice necessity / Ming-Wen An, Sumithra J. Mandrekar & Daniel J. Sargent -- Personalized management for breast cancer / George C. Zografos, Dimosthenis T. Chrysikos, Paraskevi Liakou & Flora Zagouri -- Personalized management for non-small-cell lung cancer / Martin Früh, Florent Baty, Lukas Kern, Martin P. Putora & Martin Brutsche -- Personalized management for colorectal cancer / Ana Custodio & Jaime Feliu -- Successes, challenges and future directions / Stephen J. Clarke.
  • Advances in personalized therapy for lung cancer / Nagahiro Saijo -- Biomarkers in lung cancer / Tobenna Nwizu & Ravi Salgia -- EGF receptor-targeted drugs / Tetsuya Mitsudomi -- Antiangiogenic therapies for non-small-cell lung cancer / Suresh S. Ramalingam & Chandra P. Belani -- DNA-targeted drugs / Judith Meza-Junco & Michael B. Sawyer.
  • Advances in pulmonary neuroendocrine tumor management / Kjell Öberg -- Classification / Mauro Papotti -- Molecular imaging & peptide receptor radionuclide therapy / Richard P. Baum, Harshad R. Kulkarni & Dieter Hörsch -- Biotherapy : somatostatin analogs and IFN-[alpha] / Dan Granberg -- Typical and atypical bronchial carcinoid tumors / Michael Beckles, Dalvinder Mandair, Christos Toumpanakis & Martyn Caplin -- Small-cell lung cancer and large-cell neuroendocrine tumors of the lung / David Planchard & Eric Baudin -- Thymic neuroendocrine tumors / Piero Ferolla -- Algorithm for management of bronchopulmonary neuroendocrine tumors / Kjell Öberg -- Index.
  • [1.] Non-genomic Action of Steroid Hormones: More Questions than Answers / Antimo Migliaccio, Gabriella Castoria, Antonio Bilancio, Pia Giovannelli, Marzia Di Donato and Ferdinando Auricchio -- Part I. Breast Cancer -- [2.] Progesterone Signaling to Chromatin in Breast Cancer Cells. Two Initial Cycles of Remodeling / Guillermo P. Vicent, Roser Zaurin, Cecilia Ballaré, A. Silvina Nacht, Roni H. G. Wright, Francois Le Dily, Giancarlo Castellano, Jofre Font-Mateu and Miguel Beato -- [3.] Cooperative Interactions Between c-Src, Estrogen Receptors and Receptor Tyrosine Kinases in Breast Cancer / Sarah J. Parsons, Jessica E. Pritchard, Emily M. Fox and Margaret A. Shupnik -- [4.] Cross Talk Between ER[alpha] and Src Signaling and Its Relevance to ER Status and Hormone Responsiveness / Jun Sun, Wen Zhou, Zafar Nawaz and Joyce M. Slingerland -- [5.] Post-translational Modifications of ER Alpha in Rapid Estrogen's Action / Muriel Le Romancer, Coralie Poulard, Stéphanie Sentis, and Laura Corbo -- [6.] Sex-Steroid Rapid Action and Its Role in Invasiveness and Metastasis of Breast Cancer / Marina Ines Flamini, Angel Matias Sanchez, Xiao-Dong Fu and Tommaso Simoncini -- [7.] Unraveling the Role of GPER in Breast Cancer / Rosamaria Lappano and Marcello Maggiolini -- [8.] Nongenomic Actions of Estrogens and Xenoestrogens Affecting Endocrine Cancer Cells / Cheryl S. Watson, Dragoslava Zivadinovic, Yow-Jiun Jeng, Rebecca A. Alyea, Terumi Midoro-Horiuti, Randall Goldblum and Anannya Banga -- Part II. Prostate Cancer -- [9.] Differential Functions of Stromal and Epithelial Androgen Receptor in Prostate Cancer Before and After Castration Resistant Stage / S. Lee, K.-P. Lai, S. Yeh and C. Chang -- [10.] Role of Androgens and Androgen Receptor in Prostate Cancer: Genomic and Non-Genomic Actions / Sara Marchiani, Lara Tamburrino, Monica Muratori, Lorella Bonaccorsi, Gianni Forti and Elisabetta Baldi -- [11.] Mechanisms of Signal Transduction in Prostate Cancer: The Role of PI3-Kinase Pathway in Androgen Action / Laurent Morel and Silvère Baron -- [12.] The IGF-I Axis in Prostate Cancer: The Role of Rapid Steroid Actions / Antonino Belfiore -- Androgen Receptor Pathway in Prostate Cancer: Old Target and New Drugs / Christophe Massard and Karim Fizazi -- Part III. New Tools for Steroid Receptor Analysis and Regulatory Networks -- [13.] Quantitative Visualization of Sex Steroid Receptor Functions: AR and ER[alpha] / Michael J. Bolt, Sean M. Hartig, Adam T. Szafran, Sanjay N. Mediwala, Marco Marcelli and Michael A. Mancini -- [14.] Micropatterned Surfaces as Tools for the Study of the Rapid Non-genomic Actions of Steroid Receptors / Andrew C. B. Cato, Emmanuel Oppong and Sylwia Sekula-Neuner.
  • Cell Adhesions and Signaling: A Tool for Biocompatibility Assessment / Roumen Pankov and Albena Momchilova -- Development of Provisional Extracellular Matrix on Biomaterials Interface: Lessons from In Vitro Cell Culture / George Altankov, Thomas Groth, Elisabeth Engel, Jonas Gustavsson and Marta Pegueroles, et al. -- Endothelial Progenitor Cells for Tissue Engineering and Tissue Regeneration Endothelial Progenitor Cells / Joyce Bischoff -- Dermal Precursors and the Origins of the Wound Fibroblast / Jeffrey M. Davidson -- Cell Based Therapies: What Do We Learn from Periosteal Osteochondrogenesis? / Peter J. Emans, Tim J. M. Welting and Venkatram Prasad Shastri -- Bioreactor Systems in Regenerative Medicine / Ivan Martin, Stefania A. Riboldi and David Wendt -- Biomimetic Approaches to Design of Tissue Engineering Bioreactors / Bojana Obradovic, Milica Radisic and Gordana Vunjak-Novakovic -- The Nature of the Thermal Transition Influences the Shape-Memory Behavior of Polymer Networks / Andreas Lendlein, Marc Behl and Stefan Kamlage -- Nanoengineered Systems for Regenerative Medicine Surface Engineered Polymeric Biomaterials with Improved Bio-Contact Properties / Todorka Vladkova and Natalia Krasteva -- Nanocomposites for Regenerative Medicine / Ryan Hoshi, Antonio R. Webb, Hongjin Qiu and Guillermo A. Ameer -- Role of Spatial Distribution of Matricellular Cues in Controlling Cell Functions / Daniela Guarnieri and Paolo A. Netti -- Materials Surface Effects on Biological Interactions / Josep A. Planell, Melba Navarro, George Altankov, Conrado Aparicio and Elisabeth Engel, et al. -- Chemical and Physical Modifications of Biomaterial Surfaces to Control Adhesion of Cells / Thomas Groth, Zhen-Mei Liu, Marcus Niepel, Dieter Peschel and Kristin Kirchhof, et al. -- Results of Biocompatibility Testing of Novel, Multifunctional Polymeric Implant Materials In-Vitro and In-Vivo / Dorothee Rickert, Rosemarie Fuhrmann, Bernhard Hiebl, Andreas Lendlein and Ralf-Peter Franke -- UFOs, Worms, and Surfboards: What Shapes Teach Us About Cell-Material Interactions / Julie A. Champion and Samir Mitragotri -- Nano-engineered Thin Films for Cell and Tissue-Contacting Applications / Richard F. Haglund -- Injectable Hydrogels: From Basics to Nanotechnological Features and Potential Advances / Biancamaria Baroli -- Polyelectrolyte Complexes as Smart Nanoengineered Systems for Biotechnology and Gene Delivery / Vladimir A. Izumrudov.
  • Advances in spinal fusion 2004, CRCnetBASE
  • Speakers at the symposium / Morita, M. -- Aging of the niche and the microenvironment and its role in stem cell aging / Geiger, H. -- Hematopoietic stem cell aging and cancer / Chen, Y., Ju, Z. -- DNA damage, checkpoint responses, and cell cycle control in aging stem cells / Kleinhans, K.N., Burkhalter, M.D. -- Hematopoietic stem cell aging and fate decision / Illing, A., Morita, Y. -- Stem cell therapy and stress response in pancreas and intestine -- Sperka, T., Omrani, O. -- Niche-stem cell interations and environmental influences / Tang, D. -- Stem cells and metabolism / Missios, P., Guachalla, L. -- Molecular mechanisms of muscle stem cell aging / Baig, A.H., Tümpel, S. -- Neural stem cells in development and aging / Schmidt-Strassburger, U.
  • Advances in stem cell research discusses recent advances in stem cell science, including therapeutic applications. This volume covers such topics as biomanufacturing iPS cells for therapeutic applications, techniques for controlling stem cell fate decisions, as well as current basic research in such areas as germ line stem cells, genomics and proteomics in stem cell research. It is a useful book for biology and clinical scientists, especially young investigators and stem cell biology students who are newly entering the world of stem cells research. The editors hope that the new knowledge and research outlined in this book will help contribute to new therapies for a wide variety of diseases that presently afflict humanity.
  • Part 1. Multiscale biological networks: identification, modeling and analysis -- Modular Analysis of Biological Networks / Hans-Michael Kaltenbach and Jörg Stelling -- Modeling Signaling Networks Using High-throughput Phospho-proteomics / Camille Terfve and Julio Saez-Rodriguez -- An Integrated Bayesian Framework for Identifying Phosphorylation Networks in Stimulated Cells / Tapesh Santra, Boris Kholodenko and Walter Kolch -- Signaling Cascades: Consequences of Varying Substrate and Phosphatase Levels / Elisenda Feliu, Michael Knudsen and Carsten Wiuf -- Heterogeneous Biological Network Visualization System: Case Study in Context of Medical Image Data / Erno Lindfors, Jussi Mattila, Peddinti V. Gopalacharyulu, Antti Pesonen and Jyrki Lötjönen, et al. -- Evolution of the Cognitive Proteome: From Static to Dynamic Network Models / J. Douglas Armstrong and Oksana Sorokina -- Molecular Systems Biology of Sic1 in Yeast Cell Cycle Regulation Through Multiscale Modeling / Matteo Barberis -- Proteome-Wide Screens in Saccharomyces cerevisiae Using the Yeast GFP Collection / Yolanda T. Chong, Michael J. Cox and Brenda Andrews -- Unraveling the Complex Regulatory Relationships Between Metabolism and Signal Transduction in Cancer / Michelle L. Wynn, Sofia D. Merajver and Santiago Schnell -- Part 2. Cellular decision making: adaptation, differentiation and death -- The Cell as a Thermostat: How Much does it Know? / Dennis Bray -- Stem Cell Differentiation as a Renewal-Reward Process: Predictions and Validation in the Colonic Crypt / Kiran Gireesan Vanaja, Andrew P. Feinberg and Andre Levchenko -- A Dynamic Physical Model of Cell Migration, Differentiation and Apoptosis in Caenorhabditis elegans / Antje Beyer, Ralf Eberhard, Nir Piterman, Michael O. Hengartner and Alex Hajnal, et al. -- A Modular Model of the Apoptosis Machinery / E. O. Kutumova, I. N. Kiselev, R. N. Sharipov, I. N. Lavrik and Fedor A. Kolpakov --An Ensemble Approach for Inferring Semi-quantitative Regulatory Dynamics for the Differentiation of Mouse Embryonic Stem Cells Using Prior Knowledge / Dominik Lutter, Philipp Bruns and Fabian J. Theis -- Cell Death and Life in Cancer: Mathematical Modeling of Cell Fate Decisions / Andrei Zinovyev, Simon Fourquet, Laurent Tournier, Laurence Calzone and Emmanuel Barillot -- Theoretical Aspects of Cellular Decision-Making and Information-Processing / Tetsuya J. Kobayashi and Atsushi Kamimura -- Zooming in on Yeast Osmoadaptation / Clemens Kühn and Edda Klipp -- Part 3. Spatial and temporal dymensions of intracellular dynamics -- Receptor Dynamics in Signaling / Verena Becker, Jens Timmer and Ursula Klingmüller -- A Systems-Biology Approach to Yeast Actin Cables / Tyler Drake, Eddy Yusuf and Dimitrios Vavylonis -- Modeling Morphodynamic Phenotypes and Dynamic Regimes of Cell Motion / Mihaela Enculescu and Martin Falcke -- Time-Structure of the Yeast Metabolism In vivo / Kalesh Sasidharan, Masaru Tomita, Miguel Aon, David Lloyd and Douglas B. Murray -- Coarse Graining Escherichia coli Chemotaxis: From Multi-flagella Propulsion to Logarithmic Sensing / Tine Curk, Franziska Matthäus, Yifat Brill-Karniely and Jure Dobnikar -- Self-Feedback in Actin Polymerization / Anders E. Carlsson -- Part 4. Computational tools, algorithms and theoretical methods for systems biology -- Global Optimization in Systems Biology: Stochastic Methods and Their Applications / Eva Balsa-Canto, J. R. Banga, J. A. Egea, A. Fernandez-Villaverde and G. M. de Hijas-Liste -- Mathematical Modeling of the Human Energy Metabolism Based on the Selfish Brain Theory / Matthias Chung and Britta Göbel -- Identification of Sensitive Enzymes in the Photosynthetic Carbon Metabolism / Renato Umeton, Giovanni Stracquadanio, Alessio Papini, Jole Costanza and Pietro Liò, et al. -- Formal Methods for Checking the Consistency of Biological Models / Allan Clark, Vashti Galpin, Stephen Gilmore, Maria Luisa Guerriero and Jane Hillston -- Global Parameter Identification of Stochastic Reaction Networks from Single Trajectories / Christian L. Müller, Rajesh Ramaswamy and Ivo F. Sbalzarini -- A Systems Biology View of Adaptation in Sensory Mechanisms / Pablo A. Iglesias -- Leveraging Modeling Approaches: Reaction Networks and Rules / Michael L. Blinov and Ion I. Moraru -- Part 5. Applications of systems biology in medicine, biotechnology and pharmaceutical industry --Why and How to Expand the Role of Systems Biology in Pharmaceutical Research and Development / Robert D. Phair -- Multiscale Mechanistic Modeling in Pharmaceutical Research and Development / Lars Kuepfer, Jörg Lippert and Thomas Eissing -- Re-analysis of Bipolar Disorder and Schizophrenia Gene Expression Complements the Kraepelinian Dichotomy / Kui Qian, Antonio Di Lieto, Jukka Corander, Petri Auvinen and Dario Greco -- Bringing Together Models from Bottom-Up and Top-Down Approaches: An Application for Growth of Escherichia coli on Different Carbohydrates / Andeas Kremling -- A Differential Equation Model to Investigate the Dynamics of the Bovine Estrous Cycle / H. M. T. Boer, C. Stötzel, S. Röblitz and H. Woelders -- Reducing Systems Biology to Practice in Pharmaceutical Company Research; Selected Case Studies / N. Benson, L. Cucurull-Sanchez, O. Demin, S. Smirnov and P. van der Graaf -- System-Scale Network Modeling of Cancer Using EPoC / Tobias Abenius, Rebecka Jörnsten, Teresia Kling, Linnéa Schmidt and José Sánchez, et al. -- Early Patient Stratification and Predictive Biomarkers in Drug Discovery and Development / Daphna Laifenfeld, David A. Drubin, Natalie L. Catlett, Jennifer S. Park and Aaron A. Van Hooser, et al. -- Biomedical Atlases: Systematics, Informatics and Analysis / Richard A. Baldock and Albert Burger.
  • Advances in systems biology Lane Catalog record
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  • Dawn of a new era in molecular cancer therapeutics -- Obstacles and opportunities in the clinical development of targeted therapeutics -- Tumor models for preclinical development of targeted agents -- Angiogenesis inhibitors: what is the clinical future? -- Epidermal growth factor receptor (EGFR) inhibitors in cancer therapy -- Cell survival signaling during apoptosis: implications in drug resistance and anti-cancer therapeutic development -- Targeted histone deacetylase inhibition for cancer prevention and therapy -- Inhibitors of cyclin-dependent kinase modulators for cancer therapy -- Targeting cyclooxygenase-2 for cancer prevention and treatment -- Antisense approaches in drug discovery and development -- Preclinical development of Alimta (Pemetrexed LY231514), a multitargeted antifolate.
  • Current therapies for the treatment of pulmonary arterial hypertension / Kimberly A. Smith, Dustin R. Fraidenburg & Jason X.-J. Yuan -- Etiology and prevalence of pulmonary arterial hypertension / Catharina Belge & Marion Delcroix -- Pathology and diagnosis of pulmonary arterial hypertension / Carlyne D. Cool -- Conventional therapy / Stefania Cicalini & Nicola Petrosillo -- Targeted therapies : prostaglandins / Benton Ashlock & David Poch -- Targeted therapies : endothelin receptor antagonists / Kimberly A. Smith, Dustin R. Fraidenburg & Jason X.-J. Yuan -- Stimulators and activators of soluble guanylate cyclase : potential therapeutic indications / Bobby D. Nossaman, George F. Lasker, Edward A. Pankey, Raj D. Parikh & Philip J. Kadowitz -- Surgical approaches in pulmonary arterial hypertension / Vaidehi Kaza, Jodie Moore, Srinivas Bollineni & Fernando Torres -- Monitoring and prognosis of pulmonary arterial hypertension / Melanie J. Brewis & Andrew J. Peacock -- Right ventricular failure / Raj Parikh & Philip J. Kadowitz -- Index.
  • Current guidelines for the diagnosis of testosterone deficiency / S. Arver, M. Lehtihet -- Laboratory measurement of testosterone / M.J. Diver -- Advances in testosterone replacement therapy / L.J.G. Gooren -- The role of the CAG repeat androgen receptor polymorphism in andrology / M. Zitzmann -- Late-onset hypogonadism / L.J.G Gooren -- Testosterone in obesity, metabolic syndrome, and type 2 diabetes / R.D. Stanworth, T.H. Jones --Testosterone and coronary artery disease / J.E. Nettleship ... [et al.] -- Erectile dysfunction and testosterone deficiency / M. Blute ... [et al.] -- Testosterone, bone, and osteoporosis / S.P. Tuck, R.M. Francis -- Frailty and muscle function : role for testosterone? / U. Srinivas-Shankar, F.C.W. Wu -- Testosterone effects on cognition in health and disease / M.M. Cherrier -- Anabolic applications of androgens for functional limitations associated with aging and chronic illness / S. Bhasin, T.W. Storer -- Testosterone in chronic heart failure / C.J. Malkin, T.H. Jones, K.S. Channer -- Testosterone and prostate safety / A. Morgentaler, C. Schulman.
  • Advances in the management of triple-negative breast cancer / Tiffany A. Traina & Clifford A. Hudis -- Etiology and risk factors / Laura Fejerman & Elad Ziv -- Diagnosis and pathology / Govardhanan Nagaiah & Jame Abraham -- Molecular subtypes and emerging therapeutic opportunities / Anastasia Constantinidou, Robin L. Jones & Jorge S. Reis-Filho -- Molecular profile of triple-negative breast cancer / Leonel F. Hernandez-Aya & Ana Maria Gonzalez-Angulo -- Role of metabolic rehabilitation-based approach in TNBC : biguanide metformin and more / Lev M. Berstein, Garik A. Dashyan & Vladimir F. Semiglazov -- Poly(ADP-ribose) polymerase inhibitors in triple-negative breast cancer / Mark Robson -- Targeted therapies: EGFR inhibitors / Farrah M. Datko & Maura N. Dickler -- Targeted therapies : other agents in clinical trials / Brian R. Haney, Nathan M. Shumway & George E. Peoples -- Combined therapies and future directions / Anastasia Pazaiti & Ian S. Fentiman.
  • Advances in animal models of relapse for addiction research / Friedbert Weiss -- Application of chronic extracellular recording method to studies of cocaine self-administration : method and progress / Laura L. Peoples, Alexai V. Kravitz, and Karine Guillem -- Neurochemistry of addiction : monitoring essential neurotransmitters of addiction / Stefan G. Sandberg and Paul A. Garris -- Alcohol craving and relapse prediction : imaging studies / Andreas Heinz ... [et al.] -- Integrating behavioral and molecular approaches in mouse : self-administration studies / Danielle L. Graham and David W. Self -- Neuroeconomics : implications for understanding the neurobiology of addiction / Michael L. Platt ... [et al.].
  • Advances in the pathogenesis and treatment of glioblastoma multiforme / Michael Prados -- Pathogenesis, molecular characteristics and prognostic factors for survival / Keith L. Ligon -- Standard treatment approaches for newly diagnosed glioblastoma / Soon-Tae Lee & Patrick Y. Wen -- Targeted therapeutic strategies for relapsed disease / John F. de Groot & Howard Colman -- Genes, viruses, toxins and vaccines as therapeutic modalities / Tal Shahar, Manish K. Aghi & Zvi Ram -- Drug delivery strategies for glioblastoma / Pin-Yuan Chen, Dali Yin, John Forsayeth & Krystof S. Bankiewicz -- Index.
  • Advances in the treatment of B-cell chronic lymphocytic leukemia / Michael J. Keating & Constantine Tam -- Chronic lymphocytic leukemia : diagnosis and clinical staging / Stephen P. Mulligan & Constantine S. Tam -- Genetics in chronic lymphocytic leukemia / Stephan Stilgenbauer & Thorsten Zenz -- To treat or not to treat / Marco Montillo, Alessandra Tedeschi & Enrica Morra -- Chronic lymphocytic leukemia chemotherapy : two decades of progress / Carol Moreno & Emili Montserrat -- Stem cell transplantation / David G. Maloney -- Treatment options for refractory chronic lymphocytic leukemia / Marina Motta & Alessandra Ferrajoli -- Prognostic markers in chronic lymphocytic leukemia / Renata Walewska & David Oscier -- Therapeutic agents in development and future direction / Sarah Mougalian & Susan O'Brien -- Index.
  • Advances in the treatment of chronic myeloid leukemia / Giuseppe Saglio & Carmen Fava -- Diagnosis and classification of the risk / Gabriele Gugliotta, Fausto Castagnetti, Francesca Palandri, Michele Baccarani & Gianantonio Rosti -- Genetics of chronic myeloid leukemia / Giovanna Rege-Cambrin, Emilia Giugliano & Patrizia Scaravaglio -- Molecular monitoring / Martin C. Müller, Christian Dietz & Benjamin Hanfstein -- Current targeted therapy with tyrosine kinase inhibitors / Massimo Breccia & Giuliana Alimena -- Stem cell transplantation and high-dose chemotherapy / Deena Iskander, Jane F. Apperley & Jirí Pavlu -- Treatment options for tyrosine kinase inhibitor-resistant chronic myeloid leukemia / Stephan Joseph Dorkhom, Hady Ghanem & Elias Jabbour -- Prognostic factors and future direction for chronic myeloid leukemia / David Marin & Antonia Rotolo -- Chronic myeloid leukemia : the possibility of a cure / Manuel Sobrinho-Simões, David M. Ross & Junia V. Melo -- Index.
  • Roles of the TNF family in tissue homeostasis and normal development -- Novel aspects of signaling activation by the TNF family: novel aspects of the functions of the TRAFs and cIAPs -- Novel aspects of signaling activation by the TNF: ubiquitin modification of signaling proteins -- Novel aspects of signaling activation by the TNF family: TNF signaling and gene regulatory networks -- Roles of the TNF family in infectious diseases and interrelationship of the TNF family and pattern recognition receptor signaling: roles of the TNF family in infectious diseases -- Roles of the TNF family in infectious diseases and interrelationship of the TNF family and pattern recognition receptor signaling: interrelationship of the TNF family and pattern recognition receptor signaling -- Novel aspects of immune regulation by the TNF family -- Control of lymphocyte function and repertoire by the TNF family -- Advances in applying our knowledge to therapy: mechanisms of pathological and therapeutic effects of the TNF family -- Advances in applying our knowledge to therapy: rational design of new means for therapeutic modulation of function of the TNF family -- Roles of the TNF family in neuronal development, function, and pathology -- Cell death mechanisms controlled by the TNF family -- Contributors to abstracts of talks and posters at the 12th TNF Conference -- Abstracts of talks and posters presented at the 12th TNF Conference.
  • Advances in transfusion safety Lane Catalog record
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  • Advances in transfusion safety Lane Catalog record
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    Current status of blood safety / moderator: J.S. Epstein -- Current estimates of transfusion safety worldwide / R.Y. Dodd -- Emerging infectious agents / D.A. Leiby -- New safety technologies I / moderator: H.J. Alter -- Bar code technology improves positive patient identification and transfusion safety / S.G. Sandler, A. Langeberg, L. Donhalek -- How are current blood safety priorities perceived in developed and developing world -- Pathogenesis and transfusion risk of transmissible spongiform encephalopathies / P. Brown -- Hemopure's process demonstrates TSE and viral clearance / A. Laccetti ... [et al.] -- New safety technologies II / moderator: G.M. Fitzpatrick --Movement toward international harmonization / Moderator: C. Smit Sibinga -- Movement toward international harmonisation: activities of the WHO, GCBS and Council of Europe / J. Koistinen -- Panel and open discussion / moderator: J.S. Epstein -- How do industry and government approach product standardization? / A.E. Williams -- Surveillance and management of medical errors: putting data to use / moderator: R.M. Lewis -- Event reporting systems: MERS-TM, surveillance - seeing and using the data below the waterline / H.S. Kaplan -- Surveillance of transfusion errors: putting data to use in the U.K. / M.F. Murphy -- U.S. regulatory efforts to address errors in transfusion / R.M. Lewis --Ordering blood for the wrong patient: getting inside the minds of ordering physicians / M.L. Foss, S.B. Moore -- Evidence-based transfusion practice / moderator: H.G. Klein -- RBC transfusion triggers: the evidence / J.L. Carson -- The evidence base for blood donor selection criteria / V. James -- Panel and open discussion / moderator: M. Brecher -- What drives transfusion practice? / A.E. Williams.Perspectives of paid whole and plasma donation / V. Kretschmer ... [et al.] -- Perspectives on compensated plasma donation / J.M. Bult -- What is the role for the use of incentives, including paid donations? / A.E. Williams -- Donor management in the development world: challenges and solutions / moderator: J.-P. Allain -- Donor management in a teaching hospital blood bank in West Africa / J.-P. Allain, S. Owusu-Ofori, G. Bedu-Addo -- Donor management: Malaysia and the Western Pacific Region / Y. Ayob -- Taking a closer look at blood donation in Latin America / E. Vinelli -- Donor management in South-East Asia Region (SEAR) / Z.S. Bharucha --Universal pre-storage leukoreduction - a defensible use of hospital resources: the Yale-New Haven hospital experience / J.M. Fisk, E.L. Snyder -- Blood substitutes: how close to a solution? / H.G. Klein -- Testing, inactivation, or both? / A.E. Williams -- Issues in donor recruitment and selection / moderator: A.E. Williams -- Donor recruitment and education / N. Mikkelsen -- Initiatives to improve blood donor screening / S. Kleinman, L. Katz -- Iron balance in the red blood cell donor / G.M. Brittenham -- Paid vs. voluntary plasma donation / moderator: P.F. Strengers -- International movement of plasma and plasma contracting / A. Farrugia -- Impact of source plasma standards on recovered plasma / C. Bianco --
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    Treatment of acute mania in bipolar disorder / Terence A. Ketter ... [et al.] -- Treatment of acute depression in bipolar disorder / Gary S. Sachs -- Long-term management of bipolar disorder / Charles L. Bowden and Vivek Singh -- Treatment of rapid-cycling bipolar disorder / David J. Muzina ... [et al.] -- Treatment of children and adolescents with bipolar disorder / Kiki D. Chang, Meghan Howe, and Diana I. Simeonova -- Special considerations for women with bipolar disorder / Natalie L. Rasgon and Laurel N. Zappert.
  • Recent advances in understanding of fundamental immunology have created new insights into the dynamic interactions between tumors and the immune system. This includes new understanding of T- and B-cell interaction, immune inhibitory mechanisms including the biology of T regulatory cells, myeloid suppressor cells, and dendritic cell subsets. Enhanced understanding of mechanisms underlying T-cell anergy such as arginine deprivation, immunosuppressive cytokines, defective innate and interferon response pathways, and NKG2D downregulation have all provided new insight into suppression of anti-tumors.
  • Approaches toward the study of halophilic microorganisms in their natural environments : who are they and what are they doing? / Aharon Oren -- Media and conditions for the growth of halophilic and halolerant bacteria and ardchaea / Mark A. Schneegurt -- Taxonomy of halophilic archaea and bacteria / Antonio Ventosa ... [et al.] -- Halophilic viruses / Shereen Sabet -- Microorganisms in evaporites : review of modern geomicrobiology / Tim K. Lowenstein -- Searching for microbes and DNA in ancient halite / Russell H. Vreeland -- DNA replication and repair in halophiles / Adrienne Kish and Jocelyne DiRuggiero -- Gene transfer mechanisms, population genetics/genimics and the evolution of haloarchaea / R. Thane Papke and Scott Chimileski -- Worth your salt : halophiles in education / Bonnie K. Baxter, Jaimi K. Butler and Betsy Kleba -- Halophiles in the public media / Russell H. Vreeland.
  • Nonapeptides and the evolutionary patterning of sociality / J.L. Goodson -- Sex differences in vasopressin and oxytocin innervation of the brain / G.J. de Vries -- The parvocellular vasopressinergic system and responsiveness of the hypothalamic pituitary adrenal axis during chronic stress / G. Auilera ... [et al.] -- Experimental approaches for the study of oxytocin and vasopressin gene expression in the central nervous system / E.M. Scordalakes, C. Yue and H. Gainer -- Oxytocin knockout mice: a model for studying stress-related and ingestive behaviours / J.A. Amico ... [et al.] -- The role of the vasopressin 1b receptor in aggression and other social behaviours / H.K. Caldwell, S.R. Wersinger and W.S. Young III -- Behavioural studies using temporal and spatial inactivation of the oxytocin receptor / H.-J. Lee ... [et al.] -- New aspects of oxytocin receptor function revealed by knockout mice: sociosexual behavior and control of energy balance / K. Nishimori ... [et al.] -- Regulation of vasopressin release by co-released neurotransmitters: mechanisms of purinergic and adrenergic synergism / C.D. Sladek and Z. Song -- Neuron-glia interactions in the rat supraoptic nucleus / S.H.R. Oliet ... [et al.] -- Dynamic synapses in the hypothalamic-neurohypophyseal system / K.J. Iremonger and J.S. Bains -- Endogenous modulators of synaptic transmission: cannabinoid regulation in the supraoptic nucleus / N.A. McDonald ... [et al.] -- Oxytocin and appetite / G. Leng ... [et al.] -- Neural mechanisms underlying the milk ejection burst and reflex / G.I. Hatton and Y.-F. Wang -- Oxytocin receptor signaling / D. Devost, P. Wrzal and H.H. Zingg -- Neurosteroids are excitatory in supraoptic neurons but inhibitory in the peripheral nervous system: it is all about oxytocin and progesterone receptors / C. Viero and G. Dayanithi -- Oxytocin receptors: ligand binding, signaling and cholesterol dependence / G. Gimpl ... [et al.] -- Opposite effects of oxytocin and vasopressin on the emotional expression of the fear response / D. Viviani and R. Stoop -- Multi-factorial somato-dendritic regulation of phasic spike discharge in vasopressin neurons / C.H. Brown ... [et al.] -- Neurophysiology of supraoptic neurons in C57/BL mice studied in three acute in vitro preparations / R. Sharif-Naeini ... [et al.] -- Effects of oxytocin on GABA signalling in the foetal brain during delivery / R. Khazipov, R. Tyzio and Y. Ben-Ari -- Central vasopressin and oxytocin release: regulation of complex social behaviours / A.H. Veenema and I.D. Neumann -- Interactions between dopamine and oxytocin in the control of sexual behavior / T.A. Baskerville and A.J. Douglas -- Steroidal/neuropeptide interactions in hypothalamus and amygdale related to social anxiety / E. Choleris ... [et al.] -- Functional magnetic resonance imaging and the neurobiology of vasopressin and oxytocin / C.F. Ferris -- Evolution of the arginine vasopressin 1a receptor and implications for mammalian social behaviour / G. Heckel and S. Fink -- Oxytocin, vasopressin and sociality / C.S. Carter ... [et al.] -- Neuropeptides and social behaviour: effects of oxytocin and vasopressin in humans / M. Heinrichs and G. Domes -- Chronic stress plasticity in the hypothalamic paraventricular nucleus / J.P. Herman, J. Flak and R. Jankord -- Keeping oxytocin neurons under control during stress in pregnancy / P.J. Brunton and J.A. Russell -- Rapid synapse-specific regulation of hypothalamic magnocellular neurons by glucocorticoids / S. Di and J.G. Tasker -- Vasopressin in the septum: not important versus casually involved in learning and memory - two faces of the same coin? / M. Engelmann -- Role of the endocannabinoid system in regulation of the hypothalamic-pituitary-adrenocortical axis / M.A. Steiner and C.T. Wotjak -- Molecular genetic studies of the arginine vasopressin 1a receptor (AVPR1a) and the oxytocin receptor (OXTR) in human behaviour: from autism to altruism with some notes in between / S. Israel ... [et al.] -- Oxytocin and experimental therapeutics in autism spectrum disorders / J.A. Bartz and E. Hollander -- Impact of prosocial neuropeptides on human brain function / A. Meyer-Lindenberg -- Peptide and non-peptide agonists and antagonists for the vasopressin and oxytocin V₁[a], V₁[b], V₂ and OT receptors: research tools and potential therapeutic agents / M. Manning ... [et al.] -- Affinity and efficacy of selective agonists and antagonists for vasopressin and oxytocin receptors: an "easy guide" to receptor pharmacology / B. Chini, M. Manning and G. Guillon -- Prevention of hypoxic brain oedema by the administration of vasopressin receptor antagonist OPC-31260 / A.H. Molnár ... [et al.] -- Characterization of a novel and selective V₁[B] receptor antagonist / M. Craighead ... [et al.] -- Molecular mechanisms of clinical concentrating and diluting disorders / R.W. Schrier -- Action-binding channels / Y. Noda and S. Sasaki -- Opposite potentiality of hypothalamic coexpressed neuropeptides, apelin and vasopressin in maintaining body-fluid homeostasis / C. Llorens-Cortes and F. Moos -- Recent discoveries in vasopressin-regulated aquaporin-2 trafficking / R.A. Fenton and H.B. Moeller -- Pathophysiological role of aquaporin-2 in impaired water excretion / S.-e. Ishikawa ... [et al.] -- Potential utility of aquaporin modulators for therapy of brain disorders / M.C. Papadopoulos and A.S. Verkman.
  • "This book features chapters leading physicians in disease management applying the latest scientific advances linking nutrition to the clinical practice of medicine. Each chapter offers adjuncts to standard care, fewer side-effects, improved risk-reduction or added quality of life"--Provided by publisher.
  • 1. The Management of the Extreme Sports Athlete / Omer Mei-Dan and Michael R. Carmont -- 2. Rock and Ice Climbing / Volker Schöffl -- 3. Alpine Skiing and Snowboarding Injuries / Mike Langran -- 4. Skydiving / Anton Westman -- 5. BASE Jumping / Omer Mei-Dan -- 6. Whitewater Canoeing and Rafting / Jonathan P. Folland and Kate Strachan -- 7. Surfing Injuries / Andrew T. Nathanson -- 8. Kite Surfing and Snow Kiting / Mark Tauber and Philipp Moroder -- 9. Windsurfing / Daryl A. Rosenbaum and Bree Simmons -- 10. Sailing and Yachting / Michael R. Carmont -- 11. Mountain Biking Injuries / Michael R. Carmont -- 12. Paragliding / Lior Laver and Omer Mei-Dan -- 13. Mountain, Sky, and Endurance Running / Denise Park and Michael R. Carmont -- 14. Personality Characteristics in Extreme Sports Athletes: Morbidity and Mortality in Mountaineering and BASE Jumping / Erik Monasterio -- 15. Endocrine Aspects and Responses to Extreme Sports / Karen Tordjman, Naama Constantini, and Anthony C. Hackney -- 16. Preventing Injuries in Extreme Sports Athletes / John Nyland and Yee Han Dave Lee -- 17. Rehabilitation of Extreme Sports Injuries / Peter Malliaras, Dylan Morrissey, and Nick Antoniou.
  • Adversarial reasoning 2007, CRCnetBASE
    Featuring approaches that draw from disciplines such as artificial intelligence and cognitive modeling, this book describes technologies and applications that address a broad range of practical problems, including military planning and command, military and foreign intelligence, antiterrorism and domestic security, as well as simulation and training systems. The authors present an overview of each problem and then discuss approaches and applications, combining theoretical rigor with accessibility. This comprehensive volume covers intent and plan recognition, deception discovery, and strategy formulation.
  • "The skin is one of the most frequently involved organs in adverse drug reactions. Occurring with an incidence of 1 to 5 percent for certain types of drugs, cutaneous drug eruptions are mostly benign in nature, and comprise the maculopapular type of eruption and urticaria. However, about one third of them require hospital treatment, leading to a considerable burden for the health care system. In this book, a selected group of experts provide an up-to-date, condensed and clinically relevant overview of the field of cutaneous drug eruptions, ranging from epidemiology and genetic predisposition to available therapeutic measures, including rapid drug desensitization. Reflecting the great progress made in recent years in this field, this publication will be a useful tool for a better understanding, diagnosis and management of cutaneous drug eruptions, not only for general physicians, dermatologists and clinical allergologists, but also for nurses and scientists." -- publisher's site.
  • Adverse drug reactions 2010, Springer
    Pt. 1. Target organ toxicity. -- Drug-induced liver injury / Michael Holt, Cynthia Ju.-- Drug herpersensitivity reactions involving skin / Oliver Hausmann, Benno Schnyder, Werner J. Pichler.-- Adverse drug reactions affecting blood cells / Richard H. Aster.-- Molecular mechanisms of adverse drug reactions in cardiac tissue / Reza Tabrizchi.-- Mechanisms of drug-induced nephrotoxicity / Thomas D. Nolin, Jonathan Himmelfarb.-- Receptor- and reactive intermediate-mediated mechanisms of teratogenesis / Peter G. Wells, Crystal J.J. Lee, Gordon P. McCallum, Julia Perstin, Patricia A. Harper.-- Pt. II. Mediators/Biochemical pathways.-- Role of reactive metabolites in drug-induced hepatotoxicity / A.M. Srivastava, J. L. Maggs, D. J. Antoine, D. P. Williams, D. A. Smith, B. K. Park.-- Role of cytokines in the mechanism of adverse drug reactions / Mary Jane Masson, Lindsay A. Collins, Lance R. Poh.-- Keap1-Nrf2 cellular defense pathway: mechanisms of regulation and role in protection against drug-induced toxicity / Ian M. Copple, Christopher E. Goldring, Neil R. Kitteringham, B. Kevin Park.-- Signal transduction pathways involved in drug-induced liver injury / Derick Han, Mie Shinohara, Maria D. Ybanez, Behnam Saberi, Neil Kaplowitz.-- Mictrochondrial involvement in drug-induced liver injury / Dominique Pessayre, Abdellah Mansouri, Alain Berson, Bernard Fromenty.-- Pt. III. Examples/Models.-- Mechanisms of acetaminophen-induced liver necrosis / Jack A. Hinson, Dean W. Roberts, Laura P. James.-- Drug-induced liver injury in humans: the case of Ximelagtran / M. Keisu, T.B. Andersson.-- Troglitazone / Tsuyoshi Yokoi.-- Neviropine hypersensitivity / M. Popovic, J.M. Shenton, J. Chen, A. Baban, T. Tharmanathan, B. Mannargudi, D. Abdulla, J.P. Uetrecht.-- Mechanisms of adverse drug reactions to biologics / Janet B. Clarke.-- Pt. IV. Risk factors/Screening drug candidates.-- Pharmacogenetics of idiosyncratic adverse drug reactions / Munir Pirmohamed.-- Danger hypothesis applied to idiosyncratic drug reactions / Jinze Li, Jack P. Uetrecht.-- Approaches for minimizing metabolic activation of new drug candidates in drug discovery / Sanjeev Kumar, Kaushik Mitra, Kelem Kassahun, Thomas A. Baillie.
  • A. Engineered nanomaterials: hazard, exposure and safety assessment. Interactions with the human body / Renato Colognato ... [et al.] -- Exposure assessment / Antonio Bergamaschi, Ivo Iavicoli and Kai Savolainen -- Biomonitoring / Enrico bergamaschi and Andrea Magrini -- Critical evaluation of toxicity tests / Maria Dusinska ... [et al.] -- Computational approaches / Vidana Epa, Dave Winkler and Lang Tran -- Regulation and legislation / Maureen R. Gwinn and Birgit Sokull-Klüttgen -- B. Engineered nanomaterials: impact on human health. Respiratory system / Ken Donaldson and Craig Poland -- Cardiovascular system / Jennifer B. Raftis, Nicholas L. Mills and Rodger Duffin -- Neurological system / Sandra Ceccatelli and Giuseppe Bardi -- Immune system / Diana Boraschi and Albert Duschl -- Skin / Nancy A. Monteiro-Riviere and Francesca Larese Filon -- Gastrointestinal tract / Mark A. Jepson -- Reproductive toxicity / Karin Sørig Hougaard and Luisa Campagnolo -- Genotocicity and cancer / Shareen H. Doak, Ying Liu and Chunying Chen -- C. Biomedical applications of engineered nanomaterials. Diagnostic applications / Kalcheng and Zhen Cheng -- Therapeutic applications / Cyrill Bussy ... [et al.] -- Annex: synthesis of engineered nanomaterials / Muhammet S. toprak, Gulaim A. Seisenbaeva and Vadim G. Kessler.
  • Part I. Inspirational Perspectives from History -- -- Introduction -- Ancient times -- Chinese and medieval medicine -- The twentieth century -- Modern masters -- -- Part II. Practical Advice for the Modern-Day Healer -- -- Survival tips for the younger clinician -- Civility -- Lessons learned from private practice -- A doctor's journal -- Heal thyself -- The healer.
  • Ch. 1. AEG-1/MTDH/LYRIC, the beginning: initial cloning, structure, expression profile, and regulation of expression -- Ch. 2. AEG-1/MTDH/LYRIC: clinical significance -- Ch. 3. AEG-1/MTDH/LYRIC: signaling pathways, downstream genes, interacting proteins, and regulation of tumor angiogenesis -- Ch. 4. Pleiotropic roles of AEG-1/MTDH/LYRIC in breast cancer -- Ch. 5. Drug resistance mediated by AEG-1/MTDH/LYRIC -- Ch. 6. The role of AEG-1/MTDH/LYRIC in the pathogenesis of central nervous system disease -- Ch. 7. AEG-1/MTDH/LYRIC in liver cancer -- Index.
  • Aerosols handbook. 2nd ed. 2013, CRCnetBASE
    Ch. 1. Medical and pharmaceutical aerosols / Stephen R. Marek ... [et al.] -- ch. 2. Breathing zone exposure assessment / Charles E. Rodes and Jonathan W. Thornburg -- ch. 3. Mechanisms of particle deposition / Jacky A. Rosati, Kristin K. Isaacs, and Ted B. Martonen -- ch. 4. Aerosol dose / Lev S. Ruzer, Michael G. Apte, and Richard G. Sextro -- ch. 5. Modeling deposition of inhaled particles / Kristin K. Isaacs, Jacky A. Rosati, and Ted B. Martonen -- ch. 6. Aerosol chemistry and physics / Lara A. Gundel and Hugo Destaillats -- ch. 7. Chemical analyses of particle filter deposits / Judith C. Chow and John. G. Watson -- ch. 8. Health effects of ambient ultrafine particles / Beverly S. Cohen -- ch. 9. Nanoparticle cell penetration / Steven M. Hankin and Craig A. Poland -- ch. 10. High aspect ratio nanomaterials : characterization and toxicology / Steven M. Hankin and Craig A. Poland -- ch. 11. Research and development of a new safe form of drugs / T.G. Tolstikova ... [et al.] -- ch. 12. Bioaerosols / Janet M. Macher ... [et al.] -- ch. 13. Aerosols, global climate, and the human health co-benefits of climate change mitigation / George D. Thurston and Michelle L. Bell -- ch. 14. Health effects of metals in ambient air particulate matter / Morton Lippmann -- ch. 15. Radioactive aerosols / Lev S. Ruzer -- ch. 16. Unattached fraction of radon progeny as an experimental tool in the assessment of the risk of nanoparticles / Lev S. Ruzer -- ch. 17. Filtration and sampling of aerosols by fibrous filters / A.K. Budyka, A.A. Kirsch, and B.I. Ogorodnikov -- ch. 18. Radioactive aerosols of Chernobyl accident / A.K. Budyka and B.I. Ogorodnikov -- ch. 19. Classical nucleation theory : account of dependence of the surface tension on curvature and translation-rotation correction factor / S.V. Vosel ... [et al.] -- ch. 20. Radioactive aerosol standards / Lev S. Ruzer ... [et al.] -- ch. 21. Radon and thoron in the environment : concentrations and lung cancer risk / Naomi H. Harley -- ch. 22. Risk from inhalation of the long-lived radionuclides uranium, thorium, and fallout plutonium in the atmosphere / Isabel M. Fisenne -- ch. 23. Health effects of aerosols : mechanisms and epidemiology / Ira B. Tager.
  • Skin anatomy -- Light tissue interactions -- Intense pulsed light safety: legal issues -- How to organize the IPL treatment room -- Patient selection -- Skin photorejuvenation -- Hair removal -- IPL treatment for vascular lesions -- Complications.
  • History of auricular reconstruction / Weerda, H. -- State-of-the-art autogenous ear reconstruction in cases of microtia / Firmin, F. -- Ear reconstruction with porous polyethylene implants / Berghaus, A. ... [et al.] -- Auricular prostheses / Federspil, P.A. -- Combined aesthetic and functional reconstruction of ear malformations / Kiefer, J., Staudenmaier, R. -- Combined reconstruction of congenital auricular atresia and severe microtia / Siegert, R. -- Ear reconstruction through tissue engineering / Haisch, A. -- Customized tissue engineering for ear reconstruction / Staudenmaier, R. ... [et al.].
  • Affinity chromatography. 2nd ed. 2008, Springer Protocols
    Affinity chromatography : history, perspectives, limitations, and prospects / Ana Cecília A. Roque and Christopher R. Lowe -- Immobilized metal ion affinity chromatography of native proteins / Adam Charlton and Michael Zachariou -- Affinity precipitation of proteins using metal chelates / Ashok Kumar, Igor Yu. Galaev, and Bo Mattiasson -- Immunoaffinity chromatography / Stuart R. Gallant, Vish Koppaka, and Nick Zecherle -- Dye ligand chromatography / Stuart R. Gallant, Vish Koppaka, and Nick Zecherle -- Purification of proteins using displacement chromatography / Nihal Tugcu -- Rationally designed ligands for use in affinity chromatography : an artificial protein L / Ana Cecília A. Roque and Christopher R. Lowe -- Phage display of peptides in ligand selection for use in affinity chromatography / Joanne L. Casey, Andrew M. Coley, and Michael Foley -- Preparation, analysis, and use of an affinity adsorbent for the purification of GST fusion protein / Gareth M. Forde -- Immobilized metal ion affinity chromatography of histidine-tagged fusion proteins / Adam Charlton and Michael Zachariou -- Methods for the purification of HQ-tagged proteins / Becky Godat ... [et al.] -- Amylose affinity chromatography of maltose-binding protein : purification by both native and novel matrix-assisted dialysis refolding methods / Leonard K. Pattenden and Walter G. Thomas -- Methods for detection of protein-protein and protein-DNA interactions using HaloTag / Marjeta Urh ... [et al.] -- Site-specific cleavage of fusion proteins / Adam Charlton -- The use of TAGZyme for the efficient removal of N-terminal his-tags / José Arnau ... [et al.] -- Affinity processing of cell-containing feeds using monolithic macroporous hydrogels, cryogels / Igor Yu. Galaev and Bo Mattiasson -- Monolithic bioreactors for macromolecules / Mojca Benčina ... [et al.] -- Plasmid DNA purification via the use of a dual affinity protein / Gareth M. Forde -- Affinity chromatography of phosphorylated proteins / Grigoriy S. Tchaga -- Protein separation using immobilized phospholipid chromatography / Tzong-Hsien Lee and Marie-Isabel Aguilar -- Analysis of proteins in solution using affinity capillary electrophoresis / Niels H.H. Heegaard, Christian Schou, and Jesper Østergaard.
  • This book examines the landmark 2010 Patient Protection and Affordable Care Act (ACA) from the perspective that health policy innovation is translational research directed at improving health. It delineates a new perspective about the creation and potential impact of the ACA and guides the development of health policy that is supported by best evidence that, in turn, transforms into practice, policy, and public benefit. Told by those involved in the creation and implementation of the ACA, the book reviews the history and impact of this ground-breaking legislation and recommends priorities, objectives, and next steps for translational research as the ACA is implemented. Featuring contributions from nationally renowned leaders in healthcare policy, this book adds to the public conversation about the ACA and its role in shaping health policy and contributes to a more realistic, nuanced, and productive understanding of this ground-breaking legislation by physicians, policy makers, and the public. It also provides a framework for next steps in continuing to improve U.S. health policy.
  • The Singapore healthcare system : an overview -- High quality, low cost -- Helping patients pay -- Controlling costs -- Financing -- Design and infrastructure -- Investing in the future through medical education and research -- Facing the future.
  • Aflatoxin and food safety 2005, CRCnetBASE
  • Print Material
  • The HIV/AIDS epidemic is burgeoning among African American men and women. Despite comprising only 13 percent of the population, 50 percent of new HIV diagnoses in 2004 were among African Americans. Among women and men who have sex with men (MSM), African Americans are grossly disproportionately affected by this epidemic, and this trend shows no sign of abating. This book seeks to explore some of the contextual factors that contribute to this disparity as well as ways to intervene to slow the growth of the epidemic in the U.S. This volume will focus on the history and context of HIV/AIDS in African Americans and interventions targeting specific subpopulations including adolescents, heterosexual men and women, men who have sex with men, incarcerated populations, and injection drug users. Context chapters will focus on specific contextual and structural issues related to HIV/AIDS transmission and prevention in African Americans including disparities in incarceration, racism, economic issues and substance abuse. Intervention chapters will focus on best-evidence and promising-evidence based interventions targeting HIV prevention in African Americans. These chapters will address the latest in intervention strategies, program evaluation, cost effectiveness and qualitative research methods and will include risk reduction, risk assessment, and testing and counseling.
  • African biodiversity 2005, Springer
    Complementarity of species distributions as a tool for prioritising conservation actions in Africa : testing the efficiency of using coarse-scale distribution data / J. Fjeldså, H. Tushabe -- Scorpion diversity and distribution in southern Africa : pattern and process / L. Prendini -- Madagascar as a model region for the study of tempo and pattern in adaptive radiations / M. Vences -- Commemorating Martin Eisentraut (1902-1994) - important explorer of tropical African vertebrates / W. Böhme -- Earwigs (Dermaptera:Insects) of Kenya : checklist and species new to Kenya / F. Haas ... [et al.] -- Morphometric differentiation in the East African grasshopper genus Afrophlaebo Jago, 1983 (Orthoptera:Acrididae) / A. Hochkirch -- Katydids and crickets (Orthoptera: Ensifera) of the Kakamega Forest Reserve, western Kenya / J. Holstein ... [et al.] -- Ecology and diversity of canopy associated Ceratocanthidae (Insecta:Coleoptera, Scarabaeoidea) in an Afrotropical rainforest / A. Ballerio, T. Wagner -- Human influence on the dung fauna in Afrotropical grasslands (Insecta:Coleoptera) / F.-T. Krell ... [et al.] -- Genuine Africans or Tertiary immigrants? : the genus Hydropsyche in the Afrotropical region (Insecta, Trichoptera:Hydropsychidae) / W. Mey -- Fruit-feeding butterfly communities of forest 'islands' in Ghana : survey completeness and correlates of spatial diversity / J.L. Bossart ... [et al.] -- Biogeography, diversity, and ecology of sawflies in the Afromontane region (Insecta: Symphyta) / F. Koch -- Diversity, distribution patterns, and endemism of southern African bees (Hymenoptera:Apoidea) / M. Kuhlmann -- Does grazing influence bee diversity? / C. Mayer -- The pholcid spiders of Africa (Araneae:Pholcidae) : state of knowledge and directions for future research / B.A. Huber -- West African fish diversity : distribution patterns and possible conclusions for conservation strategies / T. Moritz, K.E. Linsenmair -- Distribution and population density of the black-eared Malagasy poison frog, Mantella milotympanum Staniszewski, 1996 (Amphibia:Mantellidae) / D.R. Vieites ... [et al.] -- Amphibian and reptile diversity in the Southern Udzungwa Scarp Forest Reserve, south-eastern Tanzania / M. Menegon, S. Salvidio -- Interpreting morphological and molecular data on Indian Ocean giant tortoises / J. Gerlach -- Molecular systematics of African Colubroidea (Squamata:Serpentes) / Z.T. Nagy ... [et al.] --How to digitize large insect collections : preliminary results of the DIG project / K.-H. Lampe, D. Striebing -- Monitoring landcover changes of the Niger inland delta ecosystem (Mali) by means of ENVISAT-MERIS data / R. Seiler, E. Csaplovics, E. Vollmer -- Is geodiversity correlated to biodiversity? : a case study of the relationship between spatial heterogeneity of soil resources and tree diversity in a western Kenyan rainforest / W. Musila ... [et al.] -- Decline of woody species in the Sahel / A. Wezel -- Diversity over time and space in enset landraces (Ensete ventricosum) in Ethiopia / K. Zippel.Phylogeny and biogeography of Malagasy dwarf geckos, Lygodactylus Gray, 1864 : preliminary data from mitochondrial DNA sequences (Squamata:Gekkonidae) / M. Puente, M. Thomas, M. Vences -- Variability in a common species : the Lygodactylus capensis complex from southern and eastern Africa (Reptilia, Gekkonidae) / B. Röll -- Migration within and out of Africa : identifying knowledge gaps by data-mining the Global Register of Migratory Species / K. Riede -- Avifaunal responses to landscape-scale habitat fragmentation in the littoral forests of south-eastern Madagascar / J.E.M. Watson -- Use of satellite telemetry and remote sensing data to identify important habitats of migratory birds (Ciconia ciconia (Linnaeus 1758)) / B. Gerkmann, K. Riede -- Conservation priorities and geographical variation in flycatchers (Aves:Platysteiridae) in the Democratic Republic of Congo / M. Louette -- Rare weavers (Aves:Ploceidae) : are some Ploceus species hybrids? / A.J.F.K. Craig -- Historical determinants of mammal diversity in Africa : evolution of mammalian body mass distribution in Africa and South America during Neogene and Quaternary times / M. Nieto ... [et al.] -- Diversity and abundance of diurnal primates and forest antelopes in relation to habitat quality : a case study from the Udzungwa Mountains of Tanzania / F. Rovero, A.R. Marshall -- Small mammal diversity and reproduction along a transect in Namibia (BIOTA S 07) / P. Giere, U. Zeller -- Possible karyological affinities of small mammals from north of the Ethiopian Plateau / N. Sh. Bulatova, L.A. Lavrenchenko -- Geographic variation in the West African scaly-tailed squirrel Anomalurus pelii (Schlegel and Müller, 1845) and description of a new subspecies (Rodentia:Anomaluridae) / A.C. Schunke, R. Hutterer -- Middle ear ossicles as a diagnostic trait in African mole-rats (Rodentia:Bathyergidae) / S. Lange ... [et al.] -- Community analysis of Muridae (Mammalia, Rodentia) diversity in Guinea : a special emphasis on Mastomys species and Lassa fever distributions / C. Denys ... [et al.] -- Effects of different land use on the parasite burden and MHC constitution of two rodent species (Gerbillurus paeba, Rhabdomys pumilio) in the southern Kalahari desert / R. Harf, G. Froeschke, S. Sommer -- An assessment of the systematics of the genus Desmomys Thomas, 1910 (Rodentia:Muridae) using mitochondrial DNA sequences / L.A. Lavrenchenko, E. Verheyen -- Integrative taxonomy and phylogenetic systematics of the genets (Carnivora, Viverridae, Genetta) : a new classification of the most speciose carnivoran genus in Africa / P. Gaubert, P.J. Taylor, G. Veron --
  • After Darwin 2013, IngentaConnect
    1. Love and hatred are common to the whole sensitive creation: animal feeling in the century before Darwin -- 2. 'The Book of the Season': the conception and reception of Darwin's Expression -- 3. The backbone shiver: Darwin and the arts -- 4. Becoming an animal: Darwin and the evolution of sympathy -- 5. George Eliot, G.H. Lewes, and Darwin: animals, emotions, and morals -- 6. Between medicine and evolutionary theory: sympathy and other emotional investments in life writings by and about Charles Darwin -- 7. From entangled vision to ethical engagement: Darwin, affect, and contemporary exhibition projects -- 8. Reckoning with the emotions: neurological responses to the theory of evolution, 1870-1930 -- 9. Darwin's changing Expression and the making of the modern state -- 10. Calling the wild: selection, domestication, and species -- 11. The development of emotional life -- Afterword. The emotional and moral lives of animals: what Darwin would have said -- Index.
  • After the genome 2013, ebrary
    Faith in science : professional and public discourse on regenerative medicine / Tristan Keys, Nancy M. P. King, and Anthony Atala -- From Arrowsmith to Atwood : how did we come to disrespect science? / Ronald M. Green -- The "warfare" of science and religion and science's ethical profile / Thomas M. Lessl -- Is there a human nature? : an argument against modern excarnation / Jean Bethke Elshtain -- Crossing frontiers of science : trespassing into a godless space, or, Fulfilling our manifest destiny / Leah Ceccarelli -- The angels and devils of representing Prozac / Tod Chambers -- "Leave your medicine outside" : bioethics, spirituality, and the rhetoric of Appalachian serpent handlers / Bill J. Leonard -- Biovaluable stories and a narrative ethics of reconfigurable bodies / Arthur W. Frank -- Blacks and the language of their biotechnological future / Ezra E. H. Griffith -- Bioethics, economism, and the rhetoric of technological innovation / Howard Brody -- Technologies of the self at the end of life : pastoral power and the rhetoric of advance care planning / Lisa Kernen -- Suffering and the rhetoric of care / Judy Segal.
  • Afterlife of images 2008, Click LINK above for location/circulation status.
    Print Material
    "In 1739 China's emperor authorized the publication of a medical text that included images of children with smallpox to aid in the diagnosis and treatment of the disease. Those images made their way to Europe, where they were interpreted as indicative of the ill health and medical backwardness of the Chinese. In the mid-nineteenth century, the celebrated Cantonese painter Lam Qua collaborated with the American medical missionary Peter Parker in the creation of portraits of Chinese patients with disfiguring pathologies, rendered both before and after surgery. Europeans saw those portraits as evidence of Western medical prowess. Within China, the visual idiom that the paintings established influenced the development of medical photography. In The Afterlife of Images, Larissa N. Heinrich investigates the creation and circulation of Western medical discourses that linked ideas about disease to Chinese identity beginning in the eighteenth century." "Combining literary studies, the history of science, and visual culture studies, Heinrich analyzes the rhetoric and iconography through which medical missionaries transmitted to the West an image of China as "sick" or "diseased" She also examines the absorption of that image back into China through missionary activity, through the earliest translations of Western medical texts into Chinese, and even through the literature of Chinese nationalism. Heinrich argues that over time "scientific" Western representations of the Chinese body and culture accumulated a host of secondary meanings, taking on an afterlife with lasting consequences for conceptions of Chinese identity in China and beyond its borders."--Jacket.
  • Against their will 2013, Click LINK above for location/circulation status.
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    "The sad history of young children, especially institutionalized children, being used as cheap and available test subjects - the raw material for experimentation - started long before the atomic age and went well beyond exposure to radioactive isotopes. Experimental vaccines for hepatitis, measles, polio and other diseases, exploratory therapeutic procedures such as electroshock and lobotomy, and untested pharmaceuticals such as curare and thorazine were all tested on young children in hospitals, orphanages, and mental asylums as if they were some widely accepted intermediary step between chimpanzees and humans. Occasionally, children supplanted the chimps. Bereft of legal status or protectors, institutionalized children were often the test subjects of choice for medical researchers hoping to discover a new vaccine, prove a new theory, or publish an article in a respected medical journal. Many took advantage of the opportunity. One would be hard-pressed to identify a researcher whose professional career was cut short because he incorporated week-old infants, ward-bound juvenile epileptics, or the profoundly retarded in his experiments. In short, involuntary, non-therapeutic, and dangerous experiments on children were far from an unusual or dishonorable endeavor during the last century."--Provided by publisher.
  • Aging as risk factor in eye disease -- Age-related changes of the eyelid -- Aging effects on the optics of the eye -- Aging of the cornea -- The aging of the human lens -- The extracellular matrix of the aged human trabecular meshwork: changes of glucosaminoglycans -- Glial and mobile cells in the iris of the aging human eye -- Age-related diseases of the vitreous -- Age-related changes and/or diseases in the human retina -- Aging of the retinal pigmented epithelium -- The aging of the choroid -- Age-related macular degeneration I: types and future directions -- Age-related macular degeneration II: idiopathic macular holes -- Age-related macular degeneration III: epiretinal membranes -- Macular degeneration: ultrastructural age-related changes -- Non-exudative macular degeneration and management -- Treatment of intraocular pressure in elderly patients -- Aging of the lachrymal [lacrimal] gland -- The world according to blink: blinking and aging -- Age-related changes in the oculomotor system -- Rehabilitation of low vision in aged people -- Many suggestions to protect the eyes in aging people.
  • 1. Genetics of Age-Related Macular Degeneration / Daniel T. Kasuga, Yuhong Chen, and Kang Zhang -- 2. Modifiable Risk Factors of Age-Related Macular Degeneration / Hanna R. Coleman -- 3. Diagnosis of Age-Related Macular Degeneration / Jonathan Jonisch and Gaurav Shah -- 4. Fundus Imaging of Age-Related Macular Degeneration / Allen Chiang, Andre J. Witkin, Carl D. Regillo, and Allen C. Ho -- 5. Therapy of Nonexudative Age-Related Macular Degeneration / Annal D. Meleth, Veena R. Raiji, Nupura Krishnadev, and Emily Y. Chew -- 6. Management of Neovascular AMD / Fernando M. Penha and Philip J. Rosenfeld -- 7. Combination Therapy with Ocular Photodynamic Therapy for Age-Related Macular Degeneration / Nathan Steinle and Peter K. Kaiser -- 8. The Future of Non-neovascular Age-Related Macular Degeneration / Ketan Laud, Sri Krishna Mukkamala, Claudia Brue, and Jason S. Slakter -- 9. The Future of Neovascular Age-Related Macular Degeneration / Chirag P. Shah and Jeffrey S. Heier -- 10. The Economics of Age-Related Macular Degeneration / Gary C. Brown, Melissa M. Brown, Heidi B. Lieske, Philip A. Lieske, and Kathryn Brown.
  • pt. 1.Pathophysiology.Epidemiology of AMD /L. Ho, R. van Leeuwen, P. T. V. M. de Jong, J. R. Vingerling and C. C. W. Klaver --Genetics /L. G. Fritsche, U. Friedrich and B. H. F. Wxeber --Ageing of the Retina and Retinal Pigment Epithelium /M. E. Boulton --The Complement System in AMD /P. Charbel Issa, N. V. Chong and H. P. N. Scholl --Histopathology /A. Lommatzsch, S. Wasmuth, D. Pauleikhoff, F. G. Holz and A. C. Bird --pt. 2.Clinical Manifestations.Early AMD /M. Dietzel, D. Pauleikhoff, F. G. Holz and A. C. Bird --Clinical Manifestations of Choroidal Neovascularization in AMD /R. F. Spaide --Geographic Atrophy /M. Fleckenstein, S. Schmitz-Valckenberg, J. S. Sunness and F. G. Holz --pt. 3.Diagnostics.Fundus Imaging of AMD /R. F. Spaide --Optical Coherence Tomography /S. Wolf --Microperimetry /E. Midena and E. Pilotto --pt. 4.Prophylaxis and Therapy.Nutritional Supplementation in AMD /A. D. Meleth, V. R. Raiji, N. Krishnadev and E. Y. Chew --Laser Photocoagulation and Photodynamic Therapy /G. Soubrane --Anti-VEGF Therapy: Basics and Substances /S. Grisanti, J. Lüke and S. Peters --Anti-VEGF Therapy for AMD: Results and Guidelines /P. Mitchell and S. Foran --Combination Therapies for the Treatment of AMD /M. Barakat, N. Steinle and P. K. Kaiser --Treatment Approaches for Dry AMD /Z. Yehoshua and P. J. Rosenfeld --Surgical Therapy /B. Kirchhof --pt. 5.Rehabilitation.Reading with AMD /S. Trauzettel-Klosinski --Low Vision Aids in AMD /K. Rohrschneider.
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    Histopathology of age-related macular degeneration / Shin J. Kang and Hans E. Grossniklaus -- Immunology of age-related macular degeneration / Karl G. Csaky and Scott W. Cousins -- Genetics of age-related macular degeneration / Jennifer R. Chao, Amani A. Fawzi, and Jennifer I. Lim -- Risk factors for age-related macular degeneration and choroidal neovascularization / Kah-Guan Au Eong ... [et al.] -- Choroidal neovascularization / Frances E. Kane and Peter A. Campochiaro -- Non-exudative age-related macular degeneration / Neelakshi Bhagat and Christina J. Flaxel -- Geographic atrophy / Sharon D. Solomon and Janet S. Sunness -- Exudative (neovascular) age-related macular degeneration / Jennifer I. Lim and Jerry W. Tsong -- Indocyanine green angiography in age-related macular degeneration / Scott C.N. Oliver ... [et al.] -- Optical coherence tomography in the evaluation and management of age-related macular degeneration / David Eichenbaum and Elias Reichel -- Quantitative retinal imaging / Daniel D. Esmaili ... [et al.] -- Fundus autofluorescence in age-related macular degeneration / Rishi P. Singh, Jeffrey Y. Chung, and Peter K. Kaiser --Laser photocoagulation for choroidal neovascularization / Catherine Cukras and Stuart L. Fine -- Photocoagulation of AMD-associated CNV feeder vessels: an optimized approach / Robert W. Flower -- Photodynamic therapy / ATul Jain, Darius M. Mosfeghi, and Mark S. Blumenkranz -- Radiation treatment in age-related macular degeneration / Christina J. Flaxel and Paul T. Finger -- Anti-VEGF drugs and clinical trials / Todd R. Klesert, Jennifer I. Lim, and Phillip J. Rosenfeld -- Laser prophylaxis for age-related macular degeneration / Jason Hsu and Allen C. Ho -- Macular translocation / Kah-Guan Au Eong ... [et al.] -- Age-related macular degeneration : use of adjuncts in surgery and novel surgical approaches / Richard Scartozzi and Lawrence P. Chong -- Clinical consideration for visual rehabilitation / Susan A. Primo -- Retinal prostheses : a possible treatment for end-stage age-related macular degeneration / Thomas M. O'Hearn ... [et al.] -- Retinal pigment epithelial cell transplantation and macular reconstruction for age-related macular degeneration / Lucian V. Del Priore, Henry J. Kaplan, and Tongalp H. Tezel -- Clinical research trials / A. Frances Walonker and Kenneth R. Diddie.
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  • Ageing well 2007, CRCnetBASE
    Nutritional concerns in old age / Lisette C.P.G.M. de Groot and Wija A. van Staveren -- Regular exercise, the best investment for our old age / Marion E.T. McMurdo -- Major eye diseases of later life: cataract and age related macular degeneration / Astrid E. Fletcher -- Reminiscence in everyday talk between older people and their carers: implications for the quality of life of older people in care homes / Fiona Wilson ... [et al.] -- Retention of cognitive function in old age: why initial intelligence is important / Lawrence J. Whalley -- Health inequalities in old age in Britain / Elizabeth Breeze -- Demographic change, family support, and ageing well: developed country perspectives / Emily M.D. Grundy -- Energy efficiency and health of older people / Paul Wilkinson -- Ageing, health, and welfare: an economic perspective / Charles Normand -- Methodological issues in assessing the cost-effectiveness of interventions to improve the health of older people / Damian Walker and Cristian Aedo -- Minimum income for healthy living: older people England 2005-2006 / Jerry Morris ... [et al.] -- Responding to increasing human longevity: policy, practice, and research / David Metz.
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    "Over the past twenty years, the biomedical research community has been delivering hundreds of breakthroughs expected to extend human lifespan beyond thresholds imaginable today. However, much of this research has not yet been adopted into clinical practice, nor has it been widely publicized. Just as the Internet and mobile communications were interwoven into our everyday lives over the past two decades, biomedicine will transform our society forever by allowing people to live longer and to continue working and contributing financially to the economy longer, rather than entering into retirement and draining the economy through pensions and senior healthcare. With a refocusing of medical national resources to regenerative medicine, old age will become a concept of the past, breakthroughs in regenerative medicine will continue, and an unprecedented boom to the global economy, with an influx of older able-bodied workers and consumers, will be a reality. A leading expert in aging research, author Alex Zhavoronkov provides a helicopter view on the progress science has already made, from repairing tissue damage to growing functional organs from a single cell, and illuminates the possibilities that the scientific and medical community will soon make into realities. The Ageless Generation is an engaging work that causes us to rethink our ideas of age and ability in the modern world"--Provided by publisher.
  • Aging 2007, Springer
    Longevity -- Body architecture -- Maintenance of the body -- Multiple causes -- The ancient origins of ageing -- Mice and men -- How many genes? -- The evolution of human longevity -- Myths of life extension -- Doctors' dilemma -- The modulation of longevity -- Ageing and the angels -- Longevity, population pressure and warfare -- Dialogue between life and death -- The road discovery -- Resolution of the paradox.
  • Aging 2014, Karger
    The Commitment of human cells to senescence / R. Holliday -- Evolutionary theories of aging can explain why we age / E. Le Bourg -- Control of cell replication during aging / A. Macieira-Coelho -- Cell senescence : role in aging and age-related diseases / J. Campisi, L. Robert, -- Aging of cell membranes : facts and theories / I. Zs.-Nagy -- Oxidative stress, mitochondrial dysfunction, and the mitochondria theory of aging / Y. Kong, S.E. Trabucco, H. Zhang -- Aging of connective tissues : experimental facts and theoretical considerations / J. Labat-Robert, L. Robert -- Aging of cell communication : loss of receptor function / L. Robert, T. Fulop -- On the immunological theory of aging / T. Fulop, J.M. Witkowski, G. Pawelec, C. Alan, A. Larbi -- Aging of the brain, dementias, role of infectious proteins : facts and theories / F. Morinet -- Aging as alteration / P.-A. Miquel -- Longevity and its regulation : centenarians and beyond / L. Robert, T. Fulop.
  • Part 1. General Aspects of Aging -- Protein Redox-Regulation Mechanisms in Aging / Ufuk Çakatay -- Nitrosative Stress in Aging - Its Importance and Biological Implications in NF-κB Signaling / Predrag Ljubuncic, Einat Gochman and Abraham Z. Reznick -- Intervention with Multiple Micronutrients Including Dietary and Endogenous Antioxidants for Healthy Aging / Kedar N. Prasad -- Advanced Glycation End Products, RAGE, and Aging / Ravichandran Ramasamy, Loredana G. Bucciarelli, Shi Fang Yan and Ann Marie Schmidt -- Sirtuins and Mammalian Aging / Edward H. Sharman -- Estrogenic Modulation of Longevity by Induction of Antioxidant Enzymes / Jose Viña, Consuelo Borrás, Mari Carmen Gómez-Cabrera, Juan Gambini and Raul López-Grueso, et al. -- Mitochondrial Respiratory Function Decline in Aging and Life-Span Extension by Caloric Restriction / Shi-Bei Wu, Yu-Ting Wu, Chih-Hao Wang, Wan-Yu Lee and Yau-Huei Wei -- Methylglyoxal, Oxidative Stress, and Aging / Miklós Péter Kalapos, Kaushik M. Desai and Lingyun Wu -- Part 2. The Cardiovascular System -- Novel Strategies for Neurovascular Longevity During Aging / Kenneth Maiese, Zhao Zhong Chong, Jinling Hou and Yan Chen Shang -- Oxidative Stress in Vascular Disease / Isabelle Gorenne and Martin R. Bennett -- The Role of Mitochondrial Reactive Oxygen Species Formation for Age-Induced Vascular Dysfunction / Andreas Daiber, Joachim Kienhoefer, Rebecca Zee, Philip Wenzel and Volker Ullrich, et al. -- Aging, Oxidative Stress, and Cardiovascular Disorders / Yi Shi, Giovanni G. Camici and Thomas F. Lüscher --Oxidative Stress, Aging, and Cardiovascular Disease / G. Riccioni, V. Sblendorio and N. D'Orazio -- Antioxidation in Prevention of Cardiovascular Diseases - An Effect of Polyphenols / Jun-ichi Suzuki, Mitsuaki Isobe, Ryuichi Morishita and Ryozo Nagai -- Vascular Aging and Oxidative Stress: Hormesis and Adaptive Cellular Pathways / Nathalie Thorin-Trescases and Eric Thorin -- Role of Oxidative Stress in Mediating Elevated Blood Pressure with Aging / Julio Sartori Valinotti, Licy Yanes and Jane F. Reckelhoff -- Part 3. The Nervous System -- Melatonin, Oxidative Stress, and the Aging Brain / Stephen Bondy and Edward H. Sharman -- The SAM Strain of Mice, a Higher Oxidative Stress, Age-Dependent Degenerative Disease, and Senescence Acceleration Model / Yoichi Chiba, Atsuyoshi Shimada and Masanori Hosokawa -- Antioxidants Combined with Behavioral Enrichment Can Slow Brain Aging / Elizabeth Head -- Role of Nitric Oxide in Neurodegeneration and Vulnerability of Neuronal Cells to Nitric Oxide Metabolites and Reactive Oxygen Species / Debomoy K. Lahiri, Chandramallika Ghosh, Jack T. Rogers, Stephen Bondy and Nigel H. Greig -- Free Radical-Mediated Damage to Brain in Alzheimer's Disease: Role of Acrolein and Preclinical Promise of Antioxidant Polyphenols / Charles Ramassamy, Madeleine Arseneault and Dang Thanh Nam -- An Epigenetic Model for Susceptibility to Oxidative DNA Damage in the Aging Brain and Alzheimer's Disease / Nasser H. Zawia and Fernando Cardozo-Pelaez.
  • Aging and heart failure 2014, Springer
    This book synthesizes the major research advances in molecular, biochemical, and translational aspects of aging and heart failure over the last four decades and addresses future directions in management and drug discovery. It presents clinical issues and molecular mechanisms related to heart failure, including the changing demographics in the aging population with heart failure; hypertension and prevention of diastolic heart failure in the aging population; polypharmacy and adverse drug reactions in the aging population with heart failure; changes in the heart that accompany advancing age from humans to molecules; aging-associated alterations in myocardial inflammation and fibrosis; and aging-related changes in mitochondrial function and implications for heart failure therapy. The book succinctly summarizes the large volume of data on these key topics and highlights novel pathways that need to be explored. Featuring contributions from leading clinician-scientists, Aging and Heart Failure: Mechanisms and Management is an authoritative resource on the major clinical issues in heart failure therapy in the elderly for cardiologists, gerontologists, and internists.
  • Aging and lung disease 2012, Springer
  • Aging and the heart 2008, Springer
    Post-genomic view of aging: definition, theories and observations -- Overview of cardiovascular aging -- Molecular and cellular methodologies: a primer -- Molecular and cellular phenotypes of cardiovascular aging -- Aging of the vasculature and related systems -- Aging and the cardiovascular-related systems -- Cardiomyopathy and heart failure in aging -- Atherosclerosis, hypertension and aging -- Metabolic syndrome, diabetes and cardiometabolic risks in aging -- Gender and cardiovascular diseases in aging -- Cardiac dysrhythmias and channelopathies in aging -- Genetics of life span: lessons from model organisms -- Profiling the aging cardiovascular system: transcriptional, proteomic, SNPs, gene mapping and epigenetics analysis -- Translational research: gene, pharmacogenomics and cell-based therapy in the aging heart -- Nutrition and exercise in cardiovascular aging: metabolic and pharmacological interventions -- Aging and the frontier ahead.
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    Preface / Michael Armacost -- Introduction / Karen Eggleston and Shripad Tuljapurkar -- Population aging and economic growth / David E. Bloom -- How demography shapes individual, social, and economic transitions in Asia / Shripad Tuljapurkar -- Changing intergenerational transfers in aging Japan / Naohiro Ogawa, Amonthep Chawla and Rikiya Matsukura -- Gender, migration, and the well-being of the elderly in rural China / Shuzhuo Li ... [et al.] -- Marriage and the elderly in China / Maria Porter -- Financing health care in a rapidly aging Japan / Naoki Ikegami -- Population aging and the introduction of long-term care insurance in South Korea / Soonman Kwon -- Old-age pension reform in South Korea / Byongho Tchoe -- The diabetes epidemic in the Asia-Pacific / Karen Eggleston ... [et al.] -- Families dealing with dementia : insights from mainland China, Hong Kong, and Taiwan / Dolores Gallagher-Thompson ... [et al.] -- Elderly care in Singapore : the state as last resort / Meng-kin Lim.
  • Aging auditory system 2010, Springer
  • Aging hair 2010, Springer
    Gerontobiology of the Hair Follicle / Desmond J. Tobin -- Molecular Basis of Androgenetic Alopecia / Valerie Anne Randall -- Inflammatory Phenomena and Fibrosis in Androgenetic Alopecia / Ralph M. Trüeb -- Post-Menopausal Frontal Fibrosing Alopecia / Steven Kossard -- Female Pattern Hair Loss / M. Javed Mohungoo and Andrew G. Messenger -- Hair Growth Parameters in Pre- and Postmenopausal Women / Paradi Mirmirani, Fangyi Luo, Scott R. Youngquist, Brian K. Fisher and James Li, et al. -- Comparative Histopathology of Androgenetic Alopecia, Diffuse Alopecia, and Senescent Alopecia / David A. Whiting -- Comparative Gene Expression Profiling of Senescent and Androgenetic Alopecia Using Microarray Analysis / Paradi Mirmirani and Pratima Karnik -- The Aging Hair Pigmentary Unit / Desmond J. Tobin -- Oxidative Stress Associated Melanocyte-Loss and Hair Growth Capacity in the Aging Hair Follicle: A Model for Tissue-Specific Aging / Eva M. J. Peters -- Human Hair Follicle Melanocytes as a Proxy Cell Type in Neurodegeneration Research / Nikolaos Papageorgiou, Elisabeth Carpenter and Desmond J. Tobin -- Effect of UV Radiation on Scalp and Hair Growth / Claudine Piérard-Franchimont, Pascale Quatresooz and Gérald E. Piérard -- Hair Photoaging / Won-Soo Lee -- Effect of Tobacco Smoking on Hair / Ralph M. Trüeb -- Age-Related General Problems Affecting the Condition of Hair / Ralph M. Trüeb -- Aging of Scalp and Age-Related Disorders of Scalp / Desmond Gan and Rodney Sinclair -- Care of Aging Hair and Photoprotection / Zoe Diana Draelos -- Possibilities and Limitations for Reversal of Age-Related Hair Loss / Nina Otberg, Isabel Restrepo and Jerry Shapiro -- Possibilities and Limitations for Reversal of Age-Related Pigment Loss / Ralph M. Trüeb -- Evidence-Based Hair Transplantation / Andreas M. Finner -- Future Directions: Gene Polymorphism Diagnostics Relevant to Hair / Justine A. Ellis -- Future Directions : The Known and Unknown Roles of Hair-Follicle Stem Cell Types / Robert M. Hoffman -- Future Directions: Bioengineering the Hair Follicle / Kurt S. Stenn, Ying Zheng and Jen-Chih Hsieh -- Hair After Death / Andrew S. Wilson and Desmond J. Tobin.
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    Depression, erectile dysfunction, and coronary heart disease: an interlinked syndrome in men / Robert S. Tan -- Premature or rapid ejaculation: a neurobiological approach to management / Robert S. Tan and Michael Mistric -- Prostate cancer: controversies and developments in screening and treatments / Robert Yong and Robert S. Tan -- Growth hormone replacement in aging men / Seng-Hin Teoh and Robert S. Tan -- Bioidentical hormone replacement with testosterone in men / Christopher B. Cutter and Robert S. Tan -- Nutraceuticals as preventive medicine in aging men's health / Bruce Biundo and Robert S. Tan.Preventive gerontology in men's health: optimal aging concepts for midlife and beyond / Robert S. Tan and Akira Nishikawa -- Delaying aging for men: longevity lessons from women / Robert S. Tan and Meenu Jacob -- Diagnostic concerns and evaluation of the andropause in aging males / Robert S. Tan -- Laboratory assessments: implications in diagnostics for the andropause / Christina Ho and Robert S. Tan -- Androgens and sexuality in aging men / Kew-Kim Chew and Robert S. Tan -- Depression in aging men: are there unique gender-based therapies? / Claudia A. Orengo, Ginny Fullerton, and Robert S. Tan -- Alzheimer's disease in older men: are there gender-specific etiological issues and treatments? / Robert S. Tan and Ralph N. Martins --The effects of aging, hypogonadism, and nutrition on endurance and strength / Thomas C. Namey -- Osteoporosis in aging men / Michelle Iannuzzi-Sucich and Pamela Taxel -- Effect of androgens on muscle, bone, and hair in men / Melinda Sheffield-Moore ... [et al.] -- Obesity in aging men and the androgen relationship / Robert S. Tan and Shou-Jin Pu -- Arthritis in aging men / Carlos A. Plata and Robert S. Tan -- Cardiovascular heart disease in older men and the role of androgens / Grant C. Fowler, Emma Cid, and Robert S. Tan -- An overview of erectile dysfunction in aging men / Peter Huat-Chye Lim, Perianan Moorthy, and Robert S. Tan --
  • Aging research in yeast 2012, Springer
    Introduction -- Oxidative stresses and ageing -- The role of mitochondria in the aging processes of yeast -- The retrograde response and other pathways of interorganelle communication in yeast replicative aging -- Chronological aging in Saccharomyces cerevisiae -- Aging and the survival of quiescent and non-quiescent cells in yeast stationary-phase cultures -- Maximising the yeast chronological lifespan -- Amino acid homeostasis and chronological longevity in Saccharomyces cerevisiae -- DNA damage and DNA replication stress in yeast models of aging -- Yeast aging and apoptosis -- Cellular homeostasis in fungi: impact on the aging process -- Genome-wide analysis of yeast aging -- Genetic approaches to aging in budding and fission yeasts: new connections and new opportunities -- Evolution of asymmetric damage segregaton: a modelling approach -- Cellular ageing and the actin cyoskeleton.
  • Aging spine 2005, Springer
  • Agricultural medicine 2006, Springer
  • Agrobacterium protocols. 2nd ed. v. 1-2, 2006., Springer Protocols
    v. 2, 2006 Springer Protocols
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    Society was not prepared in 1981 for the appearance of a new infectious disease, but we have since learned that emerging and reemerging diseases will continue to challenge humanity. This work is the first history of HIV/AIDS written for a general audience that emphasizes the medical response to the epidemic. The author, a medical historian approaches the AIDS virus from philosophical and intellectual perspectives in the history of medical science, discussing the process of scientific discovery, scientific evidence, and how laboratories found the cause of AIDS and developed therapeutic interventions. Furthermore, her book places AIDS as the first infectious disease to be recognized simultaneously worldwide as a single phenomenon. After years of believing that vaccines and antibiotics would keep deadly epidemics away, researchers, doctors, patients, and the public were forced to abandon the arrogant assumption that they had conquered infectious diseases. By presenting a discussion of the history of HIV/AIDS and analyzing how aspects of society advanced or hindered the response to the disease, the book illustrates how medicine identifies and evaluates new infectious diseases quickly and what political and cultural factors limit the medical community's response.
  • AIDS conspiracy 2012, ebrary
    The conspiratorial move against HIV science and its consequences -- AIDS origin conspiracy theories in the United States and South Africa -- Who believes AIDS conspiracy theories and why leadership matters -- Science, politics, and credibility : David Gilbert fights AIDS conspiracy beliefs in US prisons -- Science, conspiracy theory, and the South African AIDS policy tragedy -- Hero scientists, cultropreneurs, living icons, and praise-singers : AIDS denialism as community -- Defending the imprimatur of science : Duesberg and the medical hypotheses saga -- The conspiratorial move and the struggle for evidence-based medicine.
  • AIDS generation 2014, Click LINK above for location/circulation status.
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    30 years and counting -- The men of the AIDS generation -- Enter HIV -- Surviving AIDS -- And then middle age -- Resilience.
  • AIDS pandemic 2005, ScienceDirect
    Virology / Phyllis J. Kanki and Myron E. Essex -- Immunology in the era of HIV/AIDS / Deborah J. Anderson -- Quantitative science / James D. Neaton -- The public health responses to HIV/AIDS: what have we learned? / Mitchell H. Katz -- AIDS and sexually transmitted disease prevention and control / Jeffrey D. Klausner -- HIV treatment meets prevention: antiretroviral therapy as prophylaxis / Myron S. Cohen and Mina C. Hosseinipour -- Challenges in developing HIV vaccines / Laurence Peiperl and Susan Buchbinder -- Microbicides / Polly F. Harrison and Trisha L. Lamphear -- AIDS behavioral prevention: unprecedented progress and emerging challenges / Willo Pequegnat -- The evolution of comprehensive AIDS clinical care / Kennth H. Mayer and Sreekanth K. Chaguturu -- The ever-changing face of AIDS: implications for patient care / Jennifer Furin, David Walton and Paul Farmer -- Economics / Samuel A. Bozzette -- Expanding global access to ARVs: the challenges of prices and patents / Michael R. Reich and Priya Bery -- The African experience / Salim S. Abdool Karim -- Asia: health meets human rights / Chris Beyrer, N. Kumarasamy and H.F. Pizer -- How HIV/AIDS changed gay life in America: and what others can learn from our experience / John-Manuel Andriote -- Drug use / Patricia Case and Steffanie A. Strathdee -- Management of HIV/AIDS in correctional settings / Frederick L. Altice and Sandra A. Springer -- Medical ethics and the law / Zita Lazzarini and Jonathan E. Von Kohorn.
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  • Air pollution 2010, CRCnetBASE
  • Air spora 2006, Springer
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  • General information on cancer staging and end-results reporting -- Head and neck -- Digestive system -- Thorax -- Musculoskeletal sites -- Skin -- Breast -- Gynecologic sites -- Genitourinary sites -- Ophthalmic sites -- Central nervous system -- Lymphoid neoplasms -- Personnel and contributors.
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    Genetics -- Immunology -- Microbiology -- Pharmacology and toxicology -- Principles of epidemiology -- Cornea and conjunctiva -- Refractive surgery -- Uveitis -- Lens -- Retina and vitreous -- Glaucoma -- Oculoplastics -- Ophthalmic pathology -- Neuro-ophthalmology -- Pediatric ophthalmology -- The eye and systemic disease -- Ocular oncology -- Trauma -- Optics -- Low vision -- Ethics and professionalism.
  • Alcohol 2008, Springer Protocols
    Acute models of ethanol exposure to mice / Timothy P. Plackett and Elizabeth J. Kovacs -- A voluntary oral-feeding rat model for pathological alcoholic liver injury / George L. Tipoe ... [et al.] -- Intragastric ethanol infusion model in rodents / Hide Tsukamoto, Hasmik Mkrtchyan, and Alla Dynnyk -- A practical method of chronic ethanol administration in mice / Ruth A. Coleman ... [et al.] -- Analysis of ethanol developmental toxicity in zebrafish / Robert L. Tanguay and Mark J. Reimers -- The avian embryo in fetal alcohol research / Susan M. Smith -- Artificial rearing / Hector D. Dominguez and Jennifer D. Thomas -- Intragastric intubation of alcohol during the perinatal period / Sandra J. Kelly and Charles R. Lawrence --Human monocytes, macrophages, and dendritic cells : alcohol treatment methods / Gyongyi Szabo and Pranoti Mandrekar -- Generation and use of primary rat cultures for studies of the effects of ethanol / Amanda Lindke, Barbara Tremper-Wells, and Michael W. Miller -- Development and properties of HepG2 cells that constitutively express CYP2E1 / Defeng Wu and Arthur I. Cederbaum -- Modeling the impact of alcohol on cortical development in a dish : strategies from mapping neural stem cell fate / Rajesh C. Miranda ... [et al.] -- Acetaldehyde-induced barrier disruption and paracellular permeability in Caco-2 cell monolayer / R.K. Rao -- Alcohol-induced oxidative stress in the liver : in vivo measurements / Gavin E. Arteel -- Isolation of Kupffer cells from rats fed chronic ethanol / Megan R. McMullen, Michele T. Pritchard, and Laura E. Nagy -- Dendritic cells in chronic in vivo ethanol exposure models / Kevin L. Legge and Annette J. Schlueter -- Formation and immunological properties of aldehyde-derived protein adducts following alcohol consumption / Geoffrey M. Thiele, Lynell W. Klassen, and Dean J. Tuma -- Assessment of natural killer (NK) and NKT cells in murine spleens and livers / Michael R. Shey and Zuhair K. Ballas --Polyclonal and antigen-specific responses of T cells and T cell subsets / Betty M. Young ... [et al.] -- B-cell studies in chronic ethanol mice / Shilpi Verma ... [et al.] -- Histological analysis of bone / Urszula T. Iwaniec, Thomas J. Wronski, and Russell T. Turner -- Assessing effects of alcohol consumption on protein synthesis in striated muscles / Thomas C. Vary and Charles H. Lang -- Methods to investigate the effects of chronic ethanol on adipocytes / Becky M. Sebastian ... [et al.] -- Proteomic approaches to identify and characterize alterations to the mitochondrial proteome in alcoholic liver disease / Shannon M. Bailey ... [et al.] -- Alcoholic liver disease and the mitochondrial ribosome : methods of analysis / Alan Cahill and Peter Sykora -- Microarray analysis of ethanol-induced changes in gene expression / Robnet T. Kerns and Michael F. Miles.
  • Alcohol and cancer 2011, Springer
    The World Health Organization has identified chronic alcohol consumption as one of the top ten risk factors for worldwide burden of disease. The International Agency for Research on Cancer has identified alcohol as carcinogenic to humans, including cancers of the upper aerodigestive tract, colon, liver and breast. Alcohol{u2019}s actions may be direct e.g. effects on retinoic acid and one-carbon metabolism, or indirect, through metabolites such as acetaldehyde and reactive oxygen species or through various signaling pathways that influence cell cycle and apoptosis that may contribute to carcinogenesis. This volume reviews the state of the art in alcohol-related cancer research in ten chapters.
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  • Alcohol and tobacco 2011, Springer
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  • Alcohol Use Disorders and the Lung: A Clinical and Pathophysiological Approach is an excellent resource for clinicians who care for individuals affected by alcohol use disorders in diverse settings. Although alcohol abuse alone does not cause acute lung injury, it renders the lung susceptible to dysfunction in response to the inflammatory stresses of sepsis, trauma, and other clinical conditions recognized to cause acute lung injury. In parallel, these same pathophysiological effects of alcohol abuse significantly increase the risk of a wide range of serious lung infections. Many clinicians involved in the primary treatment of alcohol use disorders, such as addiction psychiatrists, will find this text of interest as it will expand their understanding of the health consequences of alcohol use disorders. In parallel, clinicians who specialize in pulmonary and/or critical care medicine will have a unique resource that provides a comprehensive review of the pathophysiology of alcohol-related lung disorders and insights into evolving therapeutic options in these vulnerable individuals. Alcohol Use Disorders and the Lung: A Clinical and Pathophysiological Approach fills a gap in the literature and presents the evolving clinical research that may soon lead to novel therapies that can improve lung health in individuals with alcohol use disorders and co-existing conditions such as HIV infection.
  • Alcohol, drugs and young people Lane Catalog record
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    Policy : the principles of service organization and practice / Paul McArdle and Eilish Gilvarry -- Determinants of substance misuse / Paul McArdle -- Drug use in young people : short-term effects and long-term harms / Dan Lubman, Yvonne Bonomo and Murat Yücel -- Young people, substances and harm / Mandy Abbott, Fariah Khan and Eilish Gilvarry -- Trends in substance use and abuse in young people / Cecilia A. Essau and Peter Wennberg -- Substance use and psychiatric comorbidity in children and adolescents / Michael Farrell -- The effectiveness of universal youth substance abuse prevention programmes / David R. Foxcroft, Debby Allen and Lindsey Coombes -- Prevention of substance abuse : targeted approaches / Paul McArdle -- Treatment : course and outcome / Eilish Gilvarry and Giles Hayden -- Legal and ethical issues in the treatment of children and young people / Sarah Woolrich -- Principles of assessment for adolescents with substance use disorders / Oscar G. Bukstein and Theresa Lutka-Fedor -- Assessment instruments and outcome measurement / Oscar G. Bukstein and Theresa Lutka-Fedor -- Biological markers (drugs) / Kim Wolff -- Assessement and management in the emergency department and the paediatric unit / Joan Robson -- Brief alcohol interventions in young people : evidence and applicability / Malathi Natarajan and Eileen Kaner -- Psychological interventions for young people with substance misuse disorders / Gillian Tober -- Empirical and clinical foundations of family-based interventions for adolescent substance abuse / Howard A. Liddle, Cynthia L. Rowe and Gayle A. Dakof -- Pharmacological treatment of adolescent substance use disorder / E. Jane Marshall and K.A.H. Mirza -- The role of primary care in management of substance use/abuse / Clare Gerada -- Integrated treatment of substance use disorders and co-occurring psychiatric disorders in adolescents / Robert D. Davies and Paula D. Riggs.
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    Why study gender, alcohol and culture? /Richard W. Wilsnack, Sharon C. Wilsnack & Isidore S. Obot --Social consequences of alcohol consumption in Argentina /Myriam I. Munné --Differences in drinking patterns between men and women in Brazil /Florence Kerr-Corrêa ... [et al.] --Alcohol, gender and partner aggression: a study in the greater metropolitan area of Costa Rica /Julio Bejarano-Orozco --Women and alcohol in India /Vivek Benegal ... [et al.] --Alcohol consumption in Mexican women: implications in a syncretic culture /Martha Romero Mendoza ... [et al.] --Thecontexts of alcohol consumption by men and women in Nigeria /Akanidomo J. Ibanga ... [et al.] --Gender and alcohol in Sri Lanka /Siri Hettige & Dharmadasa Paranagama --Gender and the major consequences of alcohol consumption in Uganda /Nazarius Mbona Tumwesigye & Rogers Kasirye --Problems from women's and men's drinking in eight developing countries /Robin Room & Klara Hradilova Selin.
  • Part I. Overview and General Nutrition During Alcohol Use -- 1. Alcohol and Nutrition: An Overview / Francisco Santolaria and Emilio González-Reimers -- 2. Genetics of Alcohol Metabolism / Vijay A. Ramchandani -- 3. Laboratory Models Available to Study Alcohol and Nutrition / Nympha B. D'Souza EL-Guindy -- 4. Ethanol-Induced Lipid Peroxidation and Apoptosis in Embryopathy / Robert R. Miller Jr. -- 5. Alcohol Use During Lactation: Effects on the Mother-Infant Dyad / Julie A. Mennella -- Part II. Nutrients and Foods as Modified by Alcohol -- 6. Moderate Alcohol Administration: Oxidative Stress and Nutritional Status / Lorenzo Leggio, Anna Ferrulli, and Giovanni Addolorato -- 7. Alcohol Use and Abuse: Effects on Body Weight and Body Composition / Stefan Gazdzinski and Timothy C. Durazzo -- 8. Alcohol: Nutrition and Health Inequalities / Adrian Bonner and Margherita Grotzkyj-Giorgi -- 9. The Effect of Diet on Protein Modification by Ethanol Metabolites / Simon Worrall -- 10. Vitamin B12 De fi ciency in Alcoholics / Alberto Fragasso -- 11. American Indians/Alaskan Natives and Alcohol: Biology, Nutrition, and Positive Programs / Felina M. Cordova, Michael H. Trujillo, and Roger Dale Walker -- Part III. Nutrient Effects on Alcohol Metabolism -- 12. Metabolism of Ethanol to Acetaldehyde in the Rat Mammary Tissue: Inhibitory Effects of Plant Polyphenols and Folic Acid / Gerardo Daniel Castro and José Albe -- 13. Dietary Zinc Supplementation and Prenatal Ethanol Exposure / Peter Coyle, Brooke Summers-Pearce, Carina J. Cowley, and Allan M. Rofe -- 14. Tocotrienol and Cognitive Dysfunction Induced by Alcohol / Kanwaljit Chopra and Vinod Tiwari -- 15. Soy Products Affecting Alcohol Absorption and Metabolism / Mitsuyoshi Kano and Norihiro Kubota -- 16. Oats Supplementation and Alcohol-Induced Oxidative Tissue Damage / Christopher B. Forsyth, Yueming Tang, Robin M. Voigt, Turan Rai, and Ali Keshavarzian -- 17. Fish Oil n-3 Fatty Acids to Prevent Hippocampus and Cognitive Dysfunction in Experimental Alcoholism / Nataliya A. Babenko -- 18. Alcohol in HIV and Possible Interactions with Antiretroviral Medications / Marianna K. Baum, Sabrina Sales-Martinez, and Adriana Campa -- Part IV. Alcohol Interactions with Foods -- 19. Popular Energy Drinks and Alcohol / Erin C. Duchan -- 20. The Psychological Synergistic Effects of Alcohol and Caffeine / Ambereen Ameer and Ronald Ross Watson -- 21. Alcohol and Smoking: A Correlation of Use in Youth? / Meghan Denning and Ronald Ross Watson -- 22. Are There Physiological Correlations Between Alcohol and Tobacco Use in Adults? / Cynthia Lee and Ronald Ross Watson -- 23. Alcohol, HIV/AIDS, and Liver Disease / Tamsin A. Knox, Logan Jerger, and Alice M. Tang -- Part V. Alcohol and Chronic Diseases -- 24. Nutritional Status, Socioeconomic Factors, Alcohol, and Cataracts / Vaishali Agte and Kirtan V. Tarwadi -- 25. Alcohol Intake and High Blood Pressure / Amy Z. Fan and Yueren Zhou -- 26. Alcohol and Dyslipidemia / Indrajit Chowdhury -- 27. Dietary Antioxidants in Chronic Alcoholic Pancreatitis / Mirosław Jarosz and Ewa Rychlik -- 28. Alcohol Consumption, Lifestyle Factors, and Type 2 Diabetes / Martin D. Stricker, Henk F.J. Hendriks, and Joline W.J. Beulens -- 29. Alcohol, Overweight and Obesity / Sasiwarang Goya Wannamet -- 30. Nutrition: Alcohol and Anorectic and Bulimic Adolescents / Konstantina Magklara -- 31. Viral Infections and Cancer During Alcohol Use / Malgorzata Schlegel-Zawadzka -- Part VI. Cancer as Modified and Induced by Alcohol -- 32. Ethanol and Hepatocarcinogenesis / Helmut K. Seitz and Felix Stickel -- 33. Alcohol, Diet, and Their Interaction in Colorectal and Urinary Tract Tumors / María Marta Andreatta , Aldo R. Eynard, and Alicia Navarro -- 34. Alcohol, Acetaldehyde, and Digestive Tract Cancer / Satu Väkeväinen and Mikko Salaspuro -- 35. Alcohol Intake and Esophageal Cancer: Epidemiologic Evidence / Jill Layton and Jianjun Zhang -- Part VII. Alcohol and Liver Diseases -- 36. A Nutritional Approach to Prevent Alcoholic Liver Disease / Samuel William French -- 37. Nutraceutical Potential of Indigenous Plant Foods and Herbs for Treatment of Alcohol-Related Liver Damage / Vaishali Agte and Upendra Raghunath Gumaste -- 38. Alcohol and Nutrition as Risk Factors for Chronic Liver Disease / Stefano Bellentani, Claudio Tiribelli, and Giorgio Bedogni -- 39. Alcohol-Related Liver Disease: Roles of Insulin Resistance, Lipotoxic Ceramide Accumulation, and Endoplasmic Reticulum Stress / Suzanne M. de la Monte -- 40. Nutrition and Alcoholic and Nonalcoholic Fatty Liver Disease: The Significance of Cholesterol / Munechika Enjoji , Kenichiro Yasutake, Motoyuki Kohjima, and Makoto Nakamuta -- 41. Dietary Fatty Acids and Alcoholic Liver Disease / Takayo Kawakami, Yasuko Murakami, and Misako Okita -- 42. Nutrition in Alcoholic Steatohepatitis / Juan Caballeria, Javier Michelena, and Jose Altamirano -- 43. Alcoholic and Nonalcoholic Fatty Liver Disease and Vitamin A / Gabriela Villaça Chaves and Wilza Arantes.
  • The literature on the late effects of cancer treatment is widely scattered in different journals since all major organ systems are affected and management is based on a variety of medical and surgical treatments. The aim of ALERT Adverse Late Effects of Cancer Treatment is to offer a coherent multidisciplinary approach to the care of cancer survivors. The central paradigm is that cytotoxic multimodal therapy results in a perpetual cascade of events that affects each major organ system differently and is expressed continually over time. Essentially, radiation and chemotherapy are intense biologic modifiers that allow for cancer cure and cancer survivorship but accelerate senescence of normal tissues and increase the incidence of age-related diseases and second malignant tumors. Volume 1 of this two-volume work focuses on the general concepts and principles relevant to late effects and on the dynamic interplay of molecular, cytologic and histopathologic events that lead to altered physiologic and metabolic functions and their clinical manifestations. Chapters are also included on legal issues, economic aspects, nursing, psychological issues and quality of life.
  • The literature on the late effects of cancer treatment is widely scattered in different journals since all major organ systems are affected and management is based on a variety of medical and surgical treatments. The aim of ALERT Adverse Late Effects of Cancer Treatment is to offer a coherent multidisciplinary approach to the care of cancer survivors. The central paradigm is that cytotoxic multimodal therapy results in a perpetual cascade of events that affects each major organ system differently and is expressed continually over time. Essentially, radiation and chemotherapy are intense biologic modifiers that allow for cancer cure and cancer survivorship but accelerate senescence of normal tissues and increase the incidence of age-related diseases and second malignant tumors. Volume 2 of this two-volume work comprehensively documents potential late effects in all the normal tissue anatomic sites in the human body. The detection, diagnosis, management and prevention of effects are all considered in detail, and prognostic outcomes are discussed. Radiation risk factors and interactions with chemotherapy effects are clearly presented. The text is accompanied by numerous supportive illustrations and tables.
  • Alexia 2014, Springer
    This book is a comprehensive review of the main acquired disorders of reading: hemianopic, pure and central alexia. The authors review the diagnostic criteria for each of the different types of disorder, and the efficacy of the therapeutic studies that have attempted to remediate them. The different theoretical models of adult reading, which largely rest on how the reading system responds to injury, are also discussed and evaluated. Focal brain injury caused by stroke and brain tumors are discussed in depth as are the effects of dementia on reading. This book starts with a chapter on normal reading, followed by chapters on hemianopic alexia, pure alexia and central alexia, each structured in the same way, with: a description of the condition; a historical review of cases to date; psychophysics; consideration of the causative lesions; evidence from functional imaging studies on patients and, most importantly, a review of the evidence base for treating each condition. Finally, there is a chapter on how patient data has informed how we think about reading.
  • Alginates 2009, Springer
  • Algorithms in a nutshell. 1st ed. SU Catalog (SearchWorks), Click LINK above for location/circulation status.
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  • Algorithms in data mining using matrix and tensor methods SU Catalog (SearchWorks), Click LINK above for location/circulation status.
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  • Alicyclobacillus 2007, Springer
  • Alkaliphiles 2006, Springer
  • Allelochemicals 2006, Springer
  • Allelopathy 2006, Springer
    General -- Methodological aspects -- Physiological aspects of allelopathy -- Ecophysiology and allelopathy -- Ecological aspects of allelopathy -- Allelopathy in different environments -- Applied aspects of allelopathy.
  • Allelopathy 2004, CRCnetBASE
  • Allergic disease: pathophysiology and immunopathology -- Approach to the allergic patient -- Diagnostic tests in allergy -- Environmental allergens -- Anaphylaxis -- Insect sting allergy -- The child with asthma -- Asthma in adults: diagnosis and management -- Allergic rhinitis: diagnosis and treatment -- Sinusitis and otitis media -- Diagnosis and treatment of ocular allergy -- Urticaria and angioedema -- Atopic dermatitis -- Contact dermatitis and other contact reactions -- Food allergy and intolerance -- Allergic and allergic-like reactions to drugs and other therapeutic agents -- Antihistamines -- β-adrenergic agonists -- Theophylline -- Antileukotriene agents in the management of asthma -- Cromolyn and nedocromil: nonsteroidal anti-inflammatory therapy for asthma and other allergic diseases -- Anticholinergic agents in respiratory diseases -- Glucocorticoid therapy in asthma -- Anti-IgE therapy -- Environmental control of respiratory indoor allergens -- Allergen immunotherapy -- Controversies in allergy and allergy-like diseases -- The patient with 'too many infections'.
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  • Relations between asthma and psychological distress: an old idea revisited -- Brain and asthma: what are the linkages? -- Stress-related programming of autonomic imbalance: role in allergy and asthma -- Role of parasympathetic nerves and muscarinic receptors in allergy and asthma -- Developmental programming of allergic diseases -- Mind-body interrelationship in DNA methylation -- Neurotrophins in chronic allergic airway inflammation and remodeling -- Pathways underlying afferent signaling of bronchopulmonary immune activation to the central nervous system -- Allergen-induced neuromodulation in the respiratory tract -- Role of microbiome in regulating the HPA axisd and its relevance to allergy -- Autonomic regulation of anti-inflammatory activities from salivary glands -- Mast cell-nerve functional unit: a key component of physiologic and pathophysiologic responses -- Neural and behavioral correlates of food allergy -- Neuroendocrine-immune connection regulates chronic inflammatory disease in allergy -- Itch and the brain.
  • Allergy frontiers v. 1-6, 2009-2010., Springer
    v. 2, 2009 Springer
    v. 3, 2009 Springer
    v. 4, 2009 Springer
    v. 5, 2010 Springer
    v. 6, 2010 Springer
    v. 1. Epigenetics, allergens and risk factors -- v. 2. Classification and pathomechanisms -- v. 3. Clinical manifestations -- v. 4. Diagnosis and health economics -- v. 5. Therapy and prevention -- v. 6. Future perspectives.
  • Allergy in practice 2005, Springer
  • Allergy methods and protocols 2008, Springer Protocols
    Understanding of the molecular mechanisms of allergy /Meinir Jones --T cell : primary culture from peripheral blood /Monika Raulf-Heimsoth --Production of T-cell lines /Helga Kahlert --Production of human T-cell clones /Adrienne Verhoef --Mapping of human T-cell epitopes of allergens /Thomas ZeilerandTuomas Virtanen --Determining MHC restriction of T-cell responses /Mark Larché -- Short-term culture of CD8 cells and intracellular cytokine staining /Beejal VyasandAlistair Noble --Isolation, flow cytometric analysis, and suppression assay of CD4+ CD25+ T-regulatory cells /Hayley Jeal --Monocyte-derived dendritic cells as antigen-presenting cells in T-cell proliferation and cytokine production /Sun-sang J. Sung --Ultrasensitive ELISA for measurement of human cytokine responses in primary culture /William P. Stefura... [et al.] --Quantification of human chemokine production in TLR-stimulated and antigen-specific recall responses /Monique Stinson... [et al.] --Standardization of allergen extracts /Jørgen Nedergaard LarsenandSten Dreborg --Immunoelectrophoresis for the characterization of allergen extracts /Gitte Nordskov HansenandJørgen Nedergaard Larsen --Conjugation of haptens /Ranulfo LemusandMeryl H. Karol --Monoclonal antibodies /Helga KahlertandOliver Cromwell --Purification of antibodies /Per H. Larsson --Collection of air samples to quantify exposure to airborne allergens /Susan Gordon --Assay of air sample eluates /Anne RenströmandSusan Gordon --The halogen assay : a new technique for measuring airborne allergen /Euan Tovey... [et al.] --Measurement of specific IgG anti-Fel d 1 antibodies /Meinir G. Jones --The facilitated antigen binding (FAB) assay : a protocol to measure allergen-specific inhibitory antibody activity /James N. Francis --Microscopic identification and purity determination of pollen grains /Magdalena Rahl --Biopanning for the characterization of allergen mimotopes /Isabella Pali-SchöllandErika Jensen-Jarolim --Identification of mast cells and mast cell subpopulations /Mark BuckleyandAndrew F. Walls --Purification and characterization of mast cell tryptase and chymase from human tissues /Alan R. McEuenandAndrew F. Walls --Experimental activation of mast cells and their pharmacological modulation /Shaoheng HeandAndrew F. Walls --In situ hybridization /Kayhan T. Nouri-Aria.
  • Allergy. 4th ed. 2012, ScienceDirect
    The new edition of Allergy, by Drs. Stephen Holgate, Martin Church, David Broide, and Fernando Martinez, uses an enhanced clinical focus to provide the clear, accessible guidance you need to treat allergy patients. A more consistent format throughout features new differential diagnosis and treatment algorithms, updated therapeutic drug information in each chapter, and additional coverage of pediatric allergies. With current discussions of asthma, allergens, pollutants, drug treatment, and more, as well as access to the full text and illustrations online at www.expertconsult.com, this comprehensive resource is ideal for any non-specialist who treats patients with allergies. Prescribe appropriate therapies and effectively manage patients' allergies using detailed treatment protocols. Identify allergic conditions quickly and easily with algorithms that provide at-a-glance assistance. Explore topics in greater detail using extensive references to key literature.
  • Section 1. Overview of enzymes. Introduction to enzymes ; The limits for life define the limits for enzymes ; Enzyme kinetics ; Properties and evolution of allosteric enzymes ; Kinetics of allosteric enzymes -- Section 2. K-type enzymes. Hemoglobin ; Glycogen phosphorylase ; Phosphofructokinase ; Ribonucleotide reductase ; Hexokinase -- Section 3. V-type enzymes. Introduction to V-type enzymes ; G proteins ; Protein kinases.
  • Aloes 2004, CRCnetBASE
    Aloe vera in thermal and frostbite injuries / Michael K. Obeng J., Gary D. Motykie, Robert L. McCauley and P. Heggers -- Plant saccharides and the prevention of sun-induced skin cancer / Faith M. Strickland and Ronald P. Pelley -- Aloes and the immune system / Ian R. Tizard and Lalitha Ramamoorthy -- Bioactivity of A. arborescens preparations / Akira Yagi -- Aloe biology: the chromosomes of aloe : variation on a theme / Peter Brandham -- Aloe leaf anatomy / David F. Cutler -- Pests of aloes / Monique S.J. Simmonds.The Plants : aloes in habitat / Leonard E. Newton -- Taxonomy of Aloaceae / Gideon F. Smith and Elsie M.A. Steyn -- Aloe constituents : aloe chemistry / Tom Reynolds -- Aloe polysaccharides / Yawei Ni, Kenneth M.Yates and Ian R. Tizard -- Aloe lectins and their activities / Hiroshi Kuzuya, Kan Shimpo and Hidehiko Beppu -- Analytical methodology : the gel analysis of aloe pulp and its derivatives / Yawei Ni and Ian R. Tizard -- Analytical methodology : the exudate / Tom Reynolds -- Industrial processing and quality control of A. barbadensis / Ronald P. Pelley, Todd A. Waller and Faith M. Strickland -- Therapeutic activity of aloes: healing powers of aloes / Nicola Mascolo, Angelo A. Izzo, Francesca Borrelli, Giulia di Carlo, Lidia Sautebin and Francesco Capasso -- Aloe vera in wound healing / Gary D. Motykie and John P. Heggers.
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  • Alphabet of Galen SU Catalog (SearchWorks), Click LINK above for location/circulation status.
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    The Alphabet of Galen is a critical edition and English translation of a text describing, in alphabetical order, nearly three hundred natural products - including metals, aromatics, animal materials, and herbs - and their medicinal uses. A Latin translation of earlier Greek writings on pharmacy that have not survived, it circulated among collections of 'authorities' on medicine, including Hippocrates, Galen of Pergamun, Soranus, and Ps. Apuleius.This work presents interesting linguistic features, including otherwise unattested Greek and Latin technical terms and unique pharmacological descriptions. Nicholas Everett provides a window onto the medieval translation of ancient science and medieval conceptions of pharmacy. With a comprehensive scholarly apparatus and a contextual introduction, The Alphabet of Galen is a major resource for understanding the richness and diversity of medical history.
  • Overview of efficacy and limitation of standard and targeted therapy for malignant disease using lung cancer as a case study -- Overview of current TCM practice and potential impacts on conventional therapies -- Complementary and alternative medicine for cancer care in India: basic and clinical perspective -- Esophageal cancer -- Gastric cancer -- Colorectal cancer -- Liver cancer -- Pancreatic cancer -- Breast cancer -- Ovarian cancer -- Prostate cancer -- Kidney cancer -- Bladder cancer -- Brain cancer -- Complementary and alternative treatments for the management of cancer-related fatigue -- Complementary and alternative treatments for the management of cancer-related pain -- Challenges conducting clinical trials with herbal products in oncology -- Herbal product-drug interactions from a pharmacological perspective -- Patient-physician relationship: creating an optimal healing environment -- Legal issues in alternative treatment of cancer -- Intellectual property for alternative medicine -- Chemical-biology of natural products from medicinal plants for cancer therapy -- Flavonoids in cancer prevention and therapy: chemistry, pharmacology, mechanisms of action, and perspectives for cancer drug discovery -- Marine natural products and their synthetic derivatives for cancer therapy -- Natural product-like scaffolds for molecular dissection of macromolecular interactions and new therapeutic applications -- Mining natural product-derived molecules against cancer targets: the case of the androgen receptor in prostate cancer.
  • A scientist gone bad : how I went from the bench to the boardroom / Cynthia Robbins-Roth -- Technical writing : making sense out of manuals / Clayton R. Randall (second edition updated by Cynthia Robbins-Roth) -- Science writing : communicating with the masses / Sue Goetinck Ambrose -- Creating a publishing empire : how I gave up academic and became an entrepreneurial editor / Roger Longman -- Business information services : providing the data for industry / Mark D. Dibner -- Becoming a venture capitalist / Deepa Pakianathan -- Investment banking : dreams and reality / Peter Drake (second edition updated by Cynthia Robbins-Roth) -- How I became an analyst : science-based investment advising / Mary Ann Gray -- Entrepreneur and company founder : starting your own company and surviving / Ron Cohen -- Business development : making deals with science / Ronald Pepin -- The growth of a manager : from pure research to policy administration / Philip W. Hammer -- Regulatory affairs : keeping product development on track / Elizabeth D. Moyer -- Patent law careers : protecting the intellectual property of science / Alexandra J. Baran -- Entering biomedical and scientific consulting / Robert Roth -- Sales and marketing : so you want to sell? / Erin Hall Meade -- From doing research to moving research : my life in tech transfer / Paula Szoka -- Corporate communications : helping companies sell their stories / Tony Russo -- Executive search : the hunt for exceptional talent / Bente Hansen -- Consultant to the stars : advising CEOs for fun and profit / Carol Hall -- Biomedical consultant : specializing in technology assessment, strategic planning, and grant writing / Gail Schechter -- Science and public policy : translating between two worlds / David Applegate -- Economic development advisor : building a biotech industry for an entire country / Gina Lento -- Government agencies : directing science in the military / Genevieve Haddad -- Appendix : information resources about alternative careers for scientists / Cynthia Robbins-Roth.
  • Methods and platforms for the quantification of splice variants' expression /Laurent Bracco ... [et al.] --Pre-mRNA missplicing as a cause of human disease /Tatyana Novoyatleva ... [et al.] --Alternative splicing : therapeutic target and tool /Mariano A. Garcia-Blanco --SR proteins as potential targets for therapy /Johann Soret, Mathieu Gabut, Jamal Tazi --Misregulation of tau alternative splicing in neurodegeneration and dementia /Athena Andreadis --Spinal muscular atrophy and therapeutic prospects /Brunhilde Wirth, Lars Brichta, Eric Hahnen --Misregulation of alternative splicing causes pathogenesis in myotonic dystrophy /N. Muge Kuyumcu-Martinez, Thomas A. Cooper --Redirecting splicing to address dystrophin mutations : molecular by-pass surgery /Stephen D. Wilton, Susan Fletcher --Altered splicing in prelamin A-associated premature aging phenotypes /Annachiara De Sandre-Giovannoli, Nicolas Levy --Splicing modulation as a modifier of the CFTR function /Malka Nissim-Rafinia, Batsheva Kerem.
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    Based on a careful study of the history of Alzheimer's disease and extensive in-depth interviews with clinicians, scientists, epidemiologists, geneticists, and others, Margaret Lock highlights the limitations and the dissent implicated in this approach. She stresses that one major difficulty is the well-documented absence of behavioral signs of Alzheimer's disease in a significant proportion of elderly individuals, even when Alzheimer neuropathology is present in their brains. This incongruity makes it difficult to distinguish between what counts as normal versus pathological and, further, makes it evident that social and biological processes contribute inseparably to aging. Lock argues that basic research must continue, but it should be complemented by a realistic public health approach available everywhere that will be more effective and more humane than one focused almost exclusively on an increasingly frenzied search for a cure.
  • Alzheimer's disease 2007, Springer
  • Alzheimer's disease 2012, Karger
    The global impact of Alzheimer's disease / M.C. Carrillo, W. Thies, L.J. Bain -- The genetics of Alzheimer's disease / M.C. Schu ... [et al.] -- Current conceptual view of Alzheimer's disease / K. Herrup -- Neuropathological basis of Alzheimer's disease and Alzheimer's disease diagnosis / J.A. Schneider ... [et al.] -- Diagnostic tools : fluid biomarkers for Alzheimer's disease / H. Zetterberg, H. Hampel, K. Blennow -- MRI-and PET-based imaging markers for the diagnosis of Alzheimer's disease / S. Teipel ... [et al.] -- Changing diagnostic concepts of Alzheimer's disease / G.M. McKhann, M.S. Albert, R.A. Sperling -- Pharmacological treatment of Alzheimer's disease / L.S. Schneider -- Regulatory requirements on clinical trials in Alzheimer's disease / K. Broich ... [et al.] -- Perspectives on Alzheimer's disease : past, present and future / Z.S. Khachaturian.
  • Contemporary Approaches to Alzheimer's Disease and Frontotemporal Dementia / Erik D. Roberson -- Preparing Synthetic Aβ in Different Aggregation States / W. Blaine Stine, Lisa Jungbauer, Chunjiang Yu, Mary Jo LaDu -- Isolation of Low-n Amyloid β-Protein Oligomers from Cultured Cells, CSF, and Brain / Ganesh M. Shankar, Alfred T. Welzel, Jessica M. McDonald, Dennis J. Selkoe, Dominic M. Walsh -- Detecting Aβ*56 Oligomers in Brain Tissues / Mathew A. Sherman, Sylvain E. Lesné -- Assessing Aβ Aggregation State by Atomic Force Microscopy / Justin Legleiter -- Measuring APP Carboxy-Terminal Fragments / Luke A. Esposito -- Detection of APP Intracellular Domain in Brain Tissue / Sanjay W. Pimplikar, Anupama Suryanarayana -- Cell-Based Assays for Regulators of Tau Biology / Umesh K. Jinwal, Chad A. Dickey -- Split GFP Complementation Assay for Quantitative Measurement of Tau Aggregation In Situ / Wanjoo Chun, Geoffrey S. Waldo, Gail V. Johnson -- Apolipoprotein E Expression and Purification / Yvonne Newhouse, Karl H. Weisgraber -- Aβ Toxicity in Primary Cultured Neurons / Adriana Ferreira, Roxana C. Sinjoanu, Alexandra Nicholson, Sara Kleinschmidt -- Manipulation of Gene Expression in the Central Nervous System with Lentiviral Vectors / Binggui Sun, Li Gan -- Selecting a Mouse Model of Alzheimer's Disease / Jeannie Chin -- Monitoring Spatial Learning and Memory in Alzheimer's Disease Mouse Models Using the Morris Water Maze / Kimberly Scearce-Levie -- Step-by-Step In Situ Hybridization Method for Localizing Gene Expression Changes in the Brain / Jorge J. Palop, Erik D. Roberson, Inma Cobos -- Real-Time Visualization of Axonal Transport in Neurons / Yasuko Osakada, Bianxiao Cui -- Quantifying Biomarkers of Cognitive Dysfunction and Neuronal Network Hyperexcitability in Mouse Models of Alzheimer's Disease: Depletion of Calcium-Dependent Proteins and Inhibitory Hippocampal Remodeling / Jorge J. Palop, Lennart Mucke, Erik D. Roberson -- Epigenetic Changes in the Brain: Measuring Global Histone Modifications / Gavin Rumbaugh, Courtney A. Miller.
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    Types of articles -- Manuscript preparation -- References -- Visual presentation of data -- Ethical and legal considerations -- Editorial assessment and processing -- Grammar -- Punctuation -- Plurals -- Capitalization -- Correct and preferred usage -- Non-English words, phrases, and accent marks -- Medical indexes -- Abbreviations -- Nomenclature -- Eponyms -- Greek letters -- Units of measure -- Numbers and percentages -- Study design and statistics -- Mathematical composition -- Typography -- Manuscript editing and proofreading -- Glossary of publishing terms -- Resources.
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  • Amenorrhea 2010, Springer
    Amenorrhea: A Case-Based Clinical Guide is a comprehensive review of the current knowledge regarding normal female reproductive physiology. Replete with interesting case vignettes and providing diagnostic algorithms and therapeutic strategies for amenorrhea, Amenorrhea: A Case-Based Clinical Guide is divided into three sections. The first section is composed of two chapters that provide a thorough review of basic science and clinical knowledge about the organ systems responsible for normal physiology of the menstrual cycle. The second section includes discussion about menstrual cycle disruption as it relates to hypothalamic-pituitary dysfunction, surgical and natural menopause, genetic defects, premature ovarian failure/insufficiency and the effects of caloric excess and restriction. The third section offers an update on the physiological effects of prolonged amenorrhea induced surgically or by hypothalamic dysfunction and also includes an original chapter that focuses solely on the impact of race and ethnicity on the prevalence and diagnosis of amenorrhea. Amenorrhea: A Case-Based Clinical Guide brings together chapters from renowned experts who offer state-of-the-art, clinically useful information in a case-based, reader-friendly fashion. This title will be a welcome addition to the bookshelves of all clinicians who practice in women's health settings.
  • American men & women of science 2007., Gale Virtual Ref Lib
  • Psychiatric evaluation of adults, second edition -- Treatment of patients with delirium -- Treatment of patients with Alzheimer's disease and other dementias of late life -- Treatment of patients with HIV/AIDS -- Treatment of patients with substance use disorders, second edition -- Treatment of patients with schizophrenia, second edition -- Treatment of patients with major depressive disorder, second edition -- Treatment of patients with bipolar disorder, second edition -- Treatment of patients with panic disorder -- Treatment of patients with acute stress disorder and posttraumatic stress disorder -- Treatment of patients with eating disorders, third edition -- Treatment of patients with borderline personality disorder -- Assessment and treatment of patients with suicidal behaviors. -- Appendix: Practice guideline development process.
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  • Part I: The basic science of geriatric psychiatry --The myth, history, and science of aging /Dan G. Blazer --Demography and epidemiology of psychiatric disorders in late life /Celia F. Hybels, Dan G. Blazer, and Judith C. Hays --Physiological and clinical considerations of geriatric patient care /Robert M. Kaiser --Neuroanatomy, neurophysiology, and neuropathology of aging /Warren D. Taylor, Scott D. Moore, and Steven S. Chin --Chemical messengers /Jason D. Kilts ... [et al.] --Genetics /Robert A. Sweet and Patricia A. Wilkosz --Psychological aspects of normal aging /Ilene C. Siegler ... [et al.] --Social and economic factors related to psychiatric disorders in late life /Linda K. George.Part II: The diagnostic interview in late life --The psychiatric interview of older adults /Dan G. Blazer --Use of the laboratory in the diagnostic workup of older adults /Mugdha Thakur and P. Murali Doraiswamy --Neuropsychological assessment of dementia /Kathleen A. Welsh-Bohmer and Deborah K. Attix.Part III: Psychiatric disorders in late life --Delirium /Michael A. Fearing and Sharon K. Inouye --Dementia and milder cognitive syndromes /Constantine G. Lyketsos --Movement disorders /Burton Scott --Mood disorders /Dan G. Blazer, David C. Steffens, and Harold G. Koenig --Bipolar disorder in late life /John L. Beyer --Schizophrenia and paranoid disorders /Dilip V. Jeste, Nicole M. Lanouette, and Ipsit V. Vahia --Anxiety disorders /Eric J. Lenze and Julie Loebach Wetherell --Somatoform disorders /Marc E. Agronin --Sexual disorders /Marc E. Agronin --Bereavement /Moria J. Smoski and Larry W. Thompson --Sleep and circadian rhythm disorders /Andrew D. Krystal, Jack D. Edinger, and William K. Wohlgemuth --Alcohol and drug problems /David W. Oslin and Shahrzad Mavandadi --Personality disorders /Thomas E. Oxman --Agitation and suspiciousness /Harold W. Goforth and Lisa P. Gwyther.Part IV: Treatment of psychiatric disorders in late life --Psychopharmacology /Benoit H. Mulsant and Bruce G. Pollock --Electroconvulsive therapy /Richard D. Weiner and Andrew D. Krystal --Nutrition and physical activity /Connie Watkins Bales and Martha Elizabeth Payne --Individual and group psychotherapy /Thomas R. Lynch and Moria J. Smoski --Working with families of older adults /Lisa P. Gwyther and Diane E. Meglin --Clinical psychiatry in the nursing home /Joel E. Streim and Ira R. Katz --The continuum of caring in the long term: movement toward the community /George L. Maddox and Elise J. Bolda.Part V: Special topics --Legal, ethical, and policy issues /William E. Reichman ... [et al.] --The past and future of geriatric psychiatry /Dan G. Blazer and David C. Steffens.
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  • Part 1 : The basis of addictive disorders -- Neurobiology of addiction / George F. Koob -- Genetics of addiction / Joel Gelernter, Henry R. Kranzler -- Epidemiology of addiction / Judith S. Brook, Kerstin Pahl, Elizabeth Rubenstone -- Cross-cultural aspects of addiction / Nady el-Guebaly --Part 2 : The nature of treatment -- Assessment of the patient / Shelly F. Greenfield, Grace Hennessy -- Patient placement criteria / David Mee-Lee, David R. Gastfriend -- Evolution in addiction treatment concepts and methods / A. Thomas McLellan --Part 3 : Specific drugs of abuse -- Alcohol -- Neurobiology of alcohol / Clifford M. Knapp, Domenic A. Ciraulo, Henry R. Kranzler -- Clinical management of alcohol abuse and dependence / Hugh Myrick, Tara Wright -- Stimulants -- Neurobiology of stimulants / Margaret Haney -- Clinical management : cocaine / Thomas R. Kosten, Mehmet Sofuoglu, Tracie J. Gardner -- Clinical management : methamphetamine / Richard A. Rawson, Walter Ling -- Hallucinogens and club drugs -- Neurobiology of hallucinogens / Richard A. Glennon -- Hallucinogens and club drugs / Michael F. Weaver, Sidney H. Schnoll -- Other substances -- Nicotine and tobacco / Tony P. George, Andrea H. Weinberger -- Benzodiazepines and other sedatives and hypnotics / Adam Bisaga -- Treatment of anabolic-androgenic steroid-related disorders / Harrison G. Pope, Jr., Kirk J. Brower -- Opioids -- Neurobiology of opiates and opioids / Mary Jeanne Kreek -- Detoxification of opioids / Soteri Polydorou, Herbert D. Kleber -- Opioid maintenance treatment / Richard S. Schottenfeld -- Buprenorphine maintenance / Eric C. Strain, Michelle R. Lofwall -- Antagonists of opioids / Charles O'Brien, Kyle M. Kampman --Part 4 : Treatment modalities -- Psychodynamics / Hallie A. Lightdale, Avram H. Mack, Richard J. Frances -- Cognitive-behavioral therapies / Kathleen M. Carroll -- Motivational enhancement / Carlo C. DiClemente, Miranda Garay, Leigh Gemmell -- Twelve-step facilitation / Richard K. Ries, Marc Galanter, J. Scott Tonigan -- Contingency management / Stephen T. Higgins, Kenneth Silverman -- Network therapy / Marc Galanter -- Group therapy / David W. Brook -- Family therapy / Timothy J. O'Farrell, William Fals-Stewart --Part 5 : Rehabilitation settings -- Inpatient treatment / Roger D. Weiss, Jennifer Sharpe Potter, Rocco A. Iannucci -- Therapeutic communities / George De Leon -- Community-based treatment / Jonathan I. Ritvo, Harvey L. Causey III -- Alcoholics anonymous and other 12-step programs -- Psychological mechanisms in alcoholics anonymous / J. Scott Tonigan, Gerard J. Connors -- The history of alcoholics anonymous and the experiences of patients / Edgar P. Nace -- Outcome research on 12-step and other self-help programs / Rudolf H. Moos, Christine Timko --Part 6 : Special populations -- Adolescent substance abuse / Yifrah Kaminer -- The mentally ill substance abuser / Stephen Ross -- Women and addiction / Kathleen T. Brady, Sudie E. Back -- Perinatal substance abuse / Loretta P. Finnegan, Stephen R. Kandall -- HIV/AIDS and hepatitis C / Steven L. Batki, Kalpana I. Nathan -- Prescription drug abuse / Wilson M. Compton, Richard Denisco -- Substance use disorders among physicians / J. Wesley Boyd, John R. Knight -- Gay men and lesbians / Robert Paul Cabaj -- Minorities / Joseph Westermeyer, Daniel Dickerson --Part 7 : Special topics -- Testing to identify recent drug use / Robert L. DuPont, Carl M. Selavka -- Medical education / Erik W. Gunderson, Frances R. Levin, Petros Levounis -- Prevention of substance abuse / Richard R. Clayton, Melissa J.H. Segress, Crystal A. Caudill -- Forensic addiction psychiatry / Avram H. Mack, Monica Barros.
  • Amino acid biosynthesis 2007, Springer
  • Ch. 1. The fundamentals of mineral nutrition -- ch. 2. The chemistry of chelation -- ch. 3. The history of nutritional chelates -- ch. 4. The requirements for a nutritionally functional chelate -- ch. 5. The development of analytical methods to prove amino acid chelation -- ch. 6. Absorption of amino acid chelates from the alimentary canal -- ch. 7. The pathways for absorption of an amino acid chelate -- ch. 8. The absorption of amino acid chelates by active transport -- ch. 9. The absorption of amino acid chelates by facilitated diffusion -- ch. 10. The fate of amino acid chelates in the mucosal cell -- ch. 11. The uptake of amino acid chelates into and out of the plasma -- ch. 12. Tissue metabolism of amino acid chelates -- ch. 13. Some metabolic responses of the body to amino acid chelates -- ch. 14. Toxicity of amino acid chelates -- ch. 15. The absorption and metabolism of amino acid chelates.
  • Amino acids 2013, CRCnetBASE
    This up-to-date book presents basic concepts and recent advances in amino acid biochemistry and nutrition, providing comprehensive coverage of developments over the past 45 years. It includes information on absorption, metabolism, and excretion of amino acids while addressing protein quality and requirements. The text discusses metabolic pathways of amino acids in relation to health and disease in various organisms, as well as species differences in metabolism of amino acids. The author also presents a critical analysis of amino acid supplementation to humans and animals.
  • The emergence of electrophysiology as an aid to neurology /Mary A.B. Brazier --Electrophysiologic equipment and electrcial safety /John A. Cadwell and Richard A. Villarreal --Electroencephalography and magnetoencephalography.Electroencephalography: general principles and clinical applications /Michael J. Aminoff --Neonatal and pediatric electroencephalography /Jin S. Hahn --Electroencephalographic artifacts and benign variants /Jeffrey W. Britton --Video-EEG monitoring for epilepsy /John M. Stern and Jerome Engel, Jr. --Invasive clinical neurophysiology in epilepsy and movement disorders /William J. Marks, Jr and Kenneth D. Laxer --Topographic mapping, frequency analysis, and other quantitative techniques in electroencephalography /Marc R. Nuwer and Pedro Coutin-Churchman --Intraoperative electroencephalographic monitoring during carotid endarterectomy and cardiac surgery /Gregory D. Cascino and Frank W. Sharbrough, III --Magnetoencephalography /William W. Sutherling --Electromyography, nerve conduction studies, and related techniques.Clinical electromyography /Michael J. Aminoff --Quantitative electromyography /Mark B. Bromberg --Nerve conduction studies /Jasper R. Daube and Devon I. Rubin --Microneurography and its potential clinical applications /David Burke --Nerve excitability: a clinical translation /Matthew C. Kiernan and Cindy Shin Yi Lin --Neuromuscular ultrasound as a complement to the electrodiagnostic evaluation /Francis O. Walker and Michael S. Cartwright --Electrophysiologic study of disorders of neuuromuscular transmission /Donald B. Sanders --H-reflex and F-response studies /Morris A. Fisher --The blink reflex and other cranial nerve reflexes /Josep Valls-Sole --Electrophysiologic evaluation of movement disorders /Mark Hallett --Evaluation of the autonomic nervous system /Michael J. Aminoff --Evoked potentials and related techniques.Visual evoked potentials, electroretinography, and other diagnostic approaches to the visual system /Ari J. Green --Visual evoked potentials in infants and children /Eileen E. Birch and Vidhya Subramanian --Brainstem auditory evoked potentials: methodology, interpretation, and clinical application /Alan D. Legatt --Brainstem auditory evoked potentials in infants and children /Terence W. Picton, margot J. Taylor, and Andree Durieux-Smith --Somatosensory evoked potentials /Michael J. Aminoff and Andrew Eisen --Somatosensory evoked potentials in infants and children /Michael J. Aminoff --Diagnostic and therapeutic role of magnetic stimulation in neurologuy /Robert Chen and Nicolae Petrescu --Event-related potentials /Douglas S. Goodin --Intraoperative monitoring by evoked potential techniques /Ronald G. Emerson and David C. Adams --Bladder, bowel, and sexual dysfunction. electrophysiologic evaluation of sacral function /Simon Podnar and David B. Vodusek --Tests of vestibular function. Vestibular laboratory testing /Joseph M. Furman and Floris L. Wuyts --Electrophysiologic evaluation in special situations. Polysomnographic evaluation fo sleep disroders /Vivien C. Abad and Christian Guilleminault --Electrophysiologic evaluation of patients in the intensive care unit /G. Bryan Young and Charles F. Bolton --Electrophysiologic evaluation of brain death: a critical appraisal /Thomas P. Bleck --Electrophysiologic techniques in the evaluation of patients with suspected neurotoxic disorders /Michael J. Aminoff and James W. Albers.
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  • Amyloid and amyloidosis 2005, CRCnetBASE
    Amyloid fibrillogenesis -- AL amyloidosis -- AA amyloidosis -- Familial amyloidosis -- Central nervous system amyloidosis -- Localized amyloidosis -- Therapeutics -- Satellite symposium, Neurochem Inc.
  • Abnormal proteins are known to be associated with various pathologies. Most notably, these include amyloidoses, monoclonal protein deposits associated with plasma cell dyscrasia/multiple myeloma, cryoglobulins and various related organized and non-organized deposits. Amyloid and Related Disorders presents an overview of the most recent developments in this area including clinical presentation, etiology, pathogenesis, and differential diagnosis. The rationale for various therapies, including transplantation, is discussed and tissue diagnosis (its pitfalls and strategies for avoiding them) and laboratory support are included. The involvement of all major organ systems including renal/genitourinary, cardiac, gastrointestinal, pulmonary, peripheral nerve/central nervous system, soft tissue and bone marrow pathology is covered. This approach provides a unifying concept of these pathologic processes, which have systemic involvement, and which have, hitherto, not been universally appreciated. Awareness of these diseases among a wider audience of pathologists may increase the rate of their diagnosis as well as that of earlier diagnosis. This volume will be invaluable to specialized and general pathologists as well as cytopathologists; other medical professionals may also benefit from this concise update on the systemic amyloidoses.
  • Amyloid precursor protein 2005, CRCnetBASE
  • Amyloid proteins 2004, Springer Protocols
  • Amyloidosis 2010, Springer
    Fibril structure and fibrillogenesis -- Imaging of systemic amyloidosis -- Diagnosis and classification -- Pathogenesis of systemic amyloidoses -- Supportive care for amyloidosis -- Assessing response and prognosis in AL amyloidosis -- Localized amyloidosis -- Amyloid heart disease -- Renal amyloidosis -- Primary systemic amyloid neuropathy -- Conventional treatment of amyloidosis -- High-dose therapy in amyloidosis -- Secondary, AA, amyloidosis -- ATTR: diagnosis, prognosis, and treatment -- Other systemic forms of amyloidosis.
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  • Advances on critical care -- Airway -- Trauma -- Obstetrics -- Paediatric anaesthesia -- Cardiac arrest -- Infections, sepsis, organ dysfunction -- Perioperative care -- Quality of care in the ICU.
  • pt. I. Continuing medical education -- 1. Can I Think what I Read? / Philip D. Lumb -- pt. II. Clinical pharmacology -- 2. Pharmacological Manipulation in ICU / Daniel De Backer, Katia Donadello and Sabino Scolletta -- pt. III. Kidney -- 3. Renal Injury / Vladimir Gašparović, Ivan Gornik -- pt. IV. Ventilation: adult and paediatric -- 4. Respiratory Mechanics: Principles, Utility and Advances / Alysson R. Carvalho, Walter A. Zin -- 5. Capnometry/capnography in Prehospital Cardiopulmonary Resuscitation / Štefek Grmec, Katia Lah and Štefan Mally -- 6. Weaning from Mechanical Ventilation / Irene Cortés Puch, Andrés Esteban -- 7. Ventilatory Strategies in Acute Lung Injury / Edoardo Calderini, Sara Sher and Eleonora Allegritti -- 8. Mechanical Ventilation Beyond the PICU / Giancarlo Ottonello, Alessia Franceschi -- pt. V. Cardiovascular monitoring 9. The Nexfin Monitor--A Totally Non-Invasive Cardiac Output Monitor / Azriel Perel, Wilbert Wesselink and Jos Settels -- 10. Doppler Echocardiography in ICU Patients: Does It Improve Outcome? / Jan Poelaert -- pt. VI. Management of cardiac arrest -- 11. Mild Therapeutic Hypothermia after Cardiac Arrest / Tommaso Pellis, Vincenzo Mione and Willy P. Mercante -- 12. Nasopharyngeal Cooling During Cardiopulmonary Resuscitation / Francesco Fumagalli, Giuseppe Ristagno -- 13. Amplitude Spectrum Area as a Predictor of Successful Defibrillation / Giuseppe Ristagno, Yongqin Li, Antonino Gullo and Joe Bisera -- pt. VII. Advances in experimental and clinical research -- 14. Physiopathology and Severity of Post-Resuscitation Myocardial Dysfunction: Effects of Sodium-Hydrogen Exchanger Isoform-1 (NHE-1) Inhibitors and Erythropoietin / Raúl J. Gazmuri, Iyad M. Ayoub and Jeejabai Radhakrishnan -- 15. Experimental Treatment for Preservation of Mechanically Competent Cardiac Activity Following Cardiac Arrest / Iyad M. Ayoub, Jeejabai Radhakrishnan and Raúl J. Gazmuri -- 16. Erythropoietin Facilitates Return of Spontaneous Circulation and Survival in Victims of Out-of-Hospital Cardiac Arrest / Štefek Grmec, Matej Strand and Raúl J. Gazmuri -- pt. VIII. Infections, sepsis and organ dysfunctions -- 17. Pathophysiology of Resistance amongst Aerobic Gram-negative Bacilli in Particular Acinetobacter Species / Nia Taylor, Luciano Silvestri and Hendrick K.F. Van Saene -- 18. What Have We Learned from the Surviving Sepsis Campaign? / Jean-Louis Vincent, Katia Donadello and Leonardo Gottin -- 19. Source Control / Gabriele Sganga, Valerio Cozza -- 20. Immunoglobulins in Sepsis / Giorgio Berlot, Claudio M. Vassallo and Nicola Busetto -- pt. IX. Perioperative medicine -- 22. Perioperative Medicine--An Introduction / Antonino Gullo, Chiara M. Celestre, Annalaura Paratore and Fortunato Stimoli -- 23. Neuraxial Analgesia for Caesarean and Vaginal Delivery and Childhood Learning Disabilities / Juraj Sprung, Randall Flick and David Warner -- 24. Off-label Drugs in Perioperative Medicine: Clonidine / Cesare Gregoretti, Paolo Pelosi -- pt. X. Spinal cord stimulation -- 25. Cost Effectiveness of Spinal Cord Stimulation in the Management of Severe Angina / Mats Börjesson, Clas Mannheimer -- pt. XI. Neurotrauma -- 26. Clinical Assessment and Diagnostic Procedures in Neurotrauma / Marco Zanello, Matteo Vincenzi and Marco Bandini -- pt. XII. Disaster medicine -- 27. Disaster Preparedness / Francesco Della Corte, Pier Luigi Ingrassia -- 28. Medical Emergency Response in Toxicological Mass Casualty / Pier Luigi Ingrassia, Luca Ragazzoni and Francesco Della Corte -- pt. XIII. Quality of care -- 29. Telemedicine to Improve Care in the Critically Ill / Gastón Murias, Bernat Sales Lluis Blanch -- 30. Professionalism, Quality of Care and Pay-for-Performance Services / Antonino Gullo, Cristina Santonocito, Paolo Murabito and Marinella Astuto.
  • Anal and rectal diseases 2012, Springer
    Anal and Rectal Diseases: A Concise Manual provides a succinct reference on the subject for clinicians, including primary care physicians, gastroenterologists, general surgeons, physician's assistants and nurse practitioners. Presented in a consistent structural style that provides both a general summary of individual topics within the field along with additional details to assist those with some background knowledge in the subject area, this handy volume provides information related to the field of anorectal disease in a format that is easily accessible for rapid acquisition of knowledge. Each topic is outlined in a multidisciplinary fashion with the medical, surgical, and pathological aspects clearly detailed in each section. Each section clearly describes the condition with up-to-date management guidelines and precious clinical pearls. The volume features high quality illustrations in the form of elegant hand drawn figures, tables, photographs of physical findings, endoscopic finds and radiographs. The clinical photographs and x-rays will be of great value to gastroenterologists whose specialty is not coloproctology. Chapters on computerized tomographic colography (virtual colonoscopy) and others cover the newer technologies employed for diagnostic purposes in these diseases. Anal and Rectal Diseases: A Concise Manual provides clinicians with a tool for rapid consultation for direct patient care and management.
  • Anal fistula 2014, Springer
    1. Epidemiology, Incidence and Prevalence of Fistula in Ano / Richard L. Nelson and Herand Abcarian -- 2. Applied Anatomy / Russell K. Pearl -- 3. Relationship of Abscess to Fistula / Hernand Abcarian -- 4. Classification and Treatment of Anorectal Infections / Adrian E. Ortega and Kyle G. Cologne -- 5. Clinical Assessment of Anal Fistulas / Herand Abcarian -- 6. Clinical Assessment and Imaging Modalities of Fistula in Ano / Kyle G. Cologne, Juan Antonio Villanueva-Herrero, Enrique Montaño-Torres, and Adrian E. Ortega -- 7. Classification and Management Strategies / Herand Abcarian -- 8. Seton (Loose, Cutting, Chemical) / Varnsi R. Velchuru -- 9. Fistulotomy and Lay Open Technique / Philip Tozer and Robin K.S. Phillips -- 10. Fistulectomy with Primary Sphincter Reconstruction / Alexander Herold -- 11. Fibrin Sealant / Jose R. Cintron -- 12. Biologic Fistula Plugs / Samuel Eisenstein and Alex Jenny Ky -- 13. Synthetic Fistula Plug / Alex Jenny Ky, Michael Polcino, and Alero T. Nanna -- 14. Endorectal Advancement Flap / Christine C. Jensen -- 15. Dermal Advancement Flap / Christine C. Jensen -- 16. Ligation of Intersphincteric Fistula Tract (LIFT) / Ariane M. Abcarian -- 17. Video-Assisted Anal Fistula Teatment (VAAFT) / Piercarlo Meinero and Lorenzo Mori -- 18. Stem Cell Application in Fistula Disease / Damian Garcia-Olmo and Hector Guadalajara-Labajo -- 19. Crohn's Disease / James Fleshman and Rachel Tay -- 20. Tuberculosis Fistula / Pravin Jaiprakash Gupta -- 21. Fistula Surgery in the Era of Evidence-Based Medicine / Richard L. Nelson and Hernand Abcarian -- 22. Causes of Operative Failure / Mohammad Ali Abbass and Maher Aref Abbas 23. Recurrence/Persistence After Fistula Teatmcnt: What Next? / Hernand Abcarian.
  • Analgesia 2007, Springer
    Part I. Introduction --Peripheral and central mechanism of pain generation /H.G. Schaible --Part II.Drugs in clinical use --Opioids /C. Zöllner, C. Stein --Antipyretic analgesics: nonsteroidal antiinflammatory drugs, selective COX-2 inhibitors, paracetamol and pyrazolionones /B. Hinz, K. Brune --Local anesthetics /R. Yanagidate, G.R. Strichartz --Serotonin receptor ligands: treatments of acute migraine and cluster headache /P.J. Goadsby --Anti-convulsants and anti-depressants /A.H. Dickenson, J. Ghandehari --Part III.Compounds in preclinical development --Neuropeptide and kinin antagonists /R. G. Hill, K.R. Oliver --Glutamate receptor ligands /V. Neugebauer --Adrenergic and cholinergic compounds /R. D. Sanders, M. Maze --Cannabinoids and pain /I.J. Lever, A.S.C. Rice --Part IV.Future targets in analgesia research --Adenosine and ATP receptors /J. Sawynok --Ion channels in analgesia research /J.N. Wood --Protein kinases as potential targets for the treatment of pathological pain /R. R. Ji, Y. Kawasaki, Z. Y. Zhuang, Y.R. Wen, Y.Q. Zhang --Part V.Pain Management beyond pharmacotherapy --Placebo and endogenous mechanisms of analgesia /F. Bededetti --Limitations of pharmacotherapy: behavioral approaches to chronic pain /H. Flor, M. Diers --Subject index.
  • Analysis of clinical trials using SAS 2005, books24x7, SUNet ID login required.
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    Analysis of Stratified Data -- Multiple Comparisons and Multiple Endpoints -- Analysis of Safety and Diagnostic Data -- Interim Data Monitoring -- Analysis of Incomplete Data.
  • According to the National Institute of Health, a genome-wide association study is defined as any study of genetic variation across the entire human genome that is designed to identify genetic associations with observable traits (such as blood pressure or weight), or the presence or absence of a disease or condition. Whole genome information, when combined with clinical and other phenotype data, offers the potential for increased understanding of basic biological processes affecting human health, improvement in the prediction of disease and patient care, and ultimately the realization of the promise of personalized medicine. In addition, rapid advances in understanding the patterns of human genetic variation and maturing high-throughput, cost-effective methods for genotyping are providing powerful research tools for identifying genetic variants that contribute to health and disease. This burgeoning science merges the principles of statistics and genetics studies to make sense of the vast amounts of information available with the mapping of genomes. In order to make the most of the information available, statistical tools must be tailored and translated for the analytical issues which are original to large-scale association studies. This book will provide researchers with advanced biological knowledge who are entering the field of genome-wide association studies with the groundwork to apply statistical analysis tools appropriately and effectively. With the use of consistent examples throughout the work, chapters will provide readers with best practice for getting started (design), analyzing, and interpreting data according to their research interests. Frequently used tests will be highlighted and a critical analysis of the advantages and disadvantage complimented by case studies for each will provide readers with the information they need to make the right choice for their research.
  • Food intake and energy metabolism -- Glucose homeostasis -- Optimal glucose homeostasis -- Bistability as a fundamental phenomenon -- Biomolecular network -- P13K-AKT-TOR pathway -- Diseases related to metabolism -- Mathematical modeling of the P13K-AKT-TOR Pathway -- Fundamental decomposition -- Normal phenotype -- Disease phenotypes -- Tao of diseases.
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  • Analysis of lipid oxidation 2005, CRCnetBASE
  • The presence of oriented features in images often conveys important information about the scene or the objects contained; the analysis of oriented patterns is an important task in the general framework of image understanding. As in many other applications of computer vision, the general framework for the understanding of oriented features in images can be divided into low- and high-level analysis. In the context of the study of oriented features, low-level analysis includes the detection of oriented features in images; a measure of the local magnitude and orientation of oriented features over the entire region of analysis in the image is called the orientation field. High-level analysis relates to the discovery of patterns in the orientation field, usually by associating the structure perceived in the orientation field with a geometrical model. This book presents an analysis of several important methods for the detection of oriented features in images, and a discussion of the phase portrait method for high-level analysis of orientation fields. In order to illustrate the concepts developed throughout the book, an application is presented of the phase portrait method to computer-aided detection of architectural distortion in mammograms.
  • Part I: Basic Spike Train Statistics -- 1 Stochastic Models of Spike Trains -- 2 Estimating the Firing Rate -- 3 Analysis and Interpretation of Interval and Count Variability in Neural Spike Trains -- 4 Processing of Phase-Locked Spikes and Periodic Signals -- Part II: Pairwise Comparison of Spike Trains -- 5 Pair-Correlation in the Time and Frequency Domain -- 6 Dependence of Spike-Count Correlations on Spike-Train Statistics and Observation Time Scale -- 7 Spike Metrics -- 8 Gravitational Clustering -- Part III: Multiple-Neuron Spike Patterns -- 9 Spatio-Temporal Patterns -- 10 Unitary Event Analysis -- 11 Information Geometry of Multiple Spike Trains -- 12 Higher-Order Correlations and Cumulants -- Part IV: Population-Based Approaches -- 13 Information Theory and Systems Neuroscience -- 14 Population Coding -- 15 Stochastic Models for Multivariate Neural Point Processes: Collective Dynamics and Neural Decoding -- Part V: Practical Issues -- 16 Simulation of Stochastic Point Processes with Defined Properties -- 17 Generation and Selection of Surrogate Methods for Correlation Analysis -- 18 Bootstrap Tests of Hypotheses -- 19 Generating Random Numbers -- 20 Practically Trivial Parallel Data Processing in a Neuroscience Laboratory -- Index.
  • Pesticides: classification and properties / José L. Tadeo, Consuelo Sánchez-Brunete, Lorena González -- Sample handling of pesticides in food and environmental samples / Esther Turiel, Antonio Martín-Esteban -- Analysis of pesticides by chromatographic techniques coupled with mass spectrometry / Simon Hird -- Immunoassays and biosensors / Jeanette M. Van Emon ... [et al.] -- Quality assurance / Árpád Ambrus -- Determination of pesticides in food of vegetal origin / Frank J. Schenck, Jon W. Wong -- Determination of pesticides in food of animal origin / Antonia Garrido Frenich, Jose Luis Martinez, Adrian Covaci -- Determination of pesticides in soil / Consuelo Sánchez-Brunete, Beatriz Albero, José L. Tadeo -- Determination of pesticides in water / Jay Gan, Svetlana Bondarenko -- Sampling and analysis of pesticides in the atmosphere / Maurice Millet -- Levels of pesticides in food and food safety aspects / Kit Granby ... [et al.] -- Monitoring of pesticides in the environment / Ioannus Konstantinou ... [et al.].
  • Drug incorporation into hair / Robert Kronstrand and Karen Scott -- Passive exposure, decontamination procedures, cutoffs, and bias: pitfalls in the interpretation of hair analysis results for cocaine use / David A. Kidwell and Frederick P. Smith -- Opioids testing in hair / Michel Yegles and Robert Wennig -- Hair analysis for cocaine / Carmen Jurado -- Determination of cannabinoids in human hair / Michael Uhl -- Amphetamine determination in hair / Vincent Cirimele -- Pharmaceuticals in hair / Marjorie Cheze, Marc Deveaux, Gaelle Duffort, Francis Billault, and Gilbert Pepin -- Screening strategies in hair analysis on drugs / Hans Sachs -- Clinical applications of hair analysis / Simona Pichini, Oscar Garcia-Algar, and Rafael de la Torre -- Hair in postmortem toxicology / Robert Kronstrand and Henrik Druid -- Detection of doping agents in human hair / Pascal Kintz -- Applications of hair in drug-facilitated crime evidence / Marion Villain -- Application of hair in driving-license regranting / Manfred R. Moeller, Hans Sachs, and Fritz Pragst -- Alcohol markers in hair / Fritz Pragst and Michel Yegles -- Workplace drug testing using hair samples / Thomas Cairns, Michael Schaffer, and Virginia Hill -- Metals / Jean-Pierre Goulle.
  • Advances in biochemistry now allow us to control living systems in ways that were undreamt of a decade ago. This volume guides researchers and students through the full spectrum of experimental protocols used in biochemistry, plant biology and biotechnology.
  • Microarrays in Gene Expression Studies, p. 1-29 -- Cleaning and Normalization, p. 31-59 -- Some Cluster Analysis Methods, p. 61-97 -- Clustering of Tissue Samples, p. 99-131 -- Screening and Clustering of Genes, p. 133-183 -- Discriminant Analysis, p. 185-220 -- Supervised Classification of Tissue Samples, p. 221-251 -- Linking Microarray Data with Survival Analysis, p. 253-266.
  • Anaphylaxis 2010, Karger
    History and epidemiology -- History and classification of anaphylaxis -- Epidemiology of anaphylaxis -- Mechanisms -- T-cell response to allergens -- Anaphylaxis: mechanisms of mast cell activation -- Kinins, airway obstruction, and anaphylaxis -- Role for basophils in systemic anaphylaxis -- Human cardiac mast cells in anaphylaxis -- Diagnosis and clinical symptomatology -- Mastocytosis -- In vitro diagnosis of anaphylaxis -- Allergens and elicitors -- Insect venoms -- Classification and pathophysiology of radiocontrast media hypersensitivity -- Analgesics -- Anaphylaxis to general anesthetics -- Anaphylactic reactions to local anesthetics -- Treatment and prevention -- Anaphylaxis: acute treatment and management -- Epinephrine (adrenaline) in anaphylaxis.
  • Definition and criteria for the diagnoses of anaphylaxis -- An epidemiological approach to reducing the risk of fatal anaphylaxis -- Pathophysiology and organ damage in anaphylaxis -- Mast cells: effector cells of anaphylaxis -- Basophils in anaphylaxis -- Protease mediators of anaphylaxis -- Aspirin and NSAID reactions: diagnosis, pathophysiology, and management -- IgE-dependent and independent effector mechanisms in human and murine anaphylaxis -- Food-induced anaphylaxis -- Antibiotic-induced anaphylaxis -- Anaphylaxis during radiological procedures and in the peri-operative setting -- Hymenoptera-induced hypersensitivity reactions and anaphylaxis -- Idiopathic anaphylaxis -- Exercise-induced anaphylaxis and food-dependent exercise-induced anaphylaxis -- Mastocytosis and mast cell activation syndromes presenting as anaphylaxis -- Anaphylaxis in mastocytosis -- Flushing and urticarial syndromes presenting as anaphylaxis -- Pharmacologic management of acute anaphylaxis -- Drug desensitizations in the management of allergy and anaphylaxis to chemotherapeutic agents and monoclonal antibodies -- Rapid desensitizations for antibiotic-induced hypersensitivity reactions and anaphylaxis -- Induction of tolerance for food-induced anaphylaxis -- Management of anaphylaxis: relevance of causes and future trends in treatment.
  • General anatomy of the heart in the chest -- Age-related cardiac changes -- Aortic valve -- Mitral valve -- Tricuspid and pulmonary valve -- Cardiomyopathies -- Ischemic heart disease -- Right ventricular diseases -- Diseases of the aorta -- Pericardial diseases -- Prosthetic heart valves -- Infective endocarditis and related conditions -- Neoplasm, cardiac tumor -- Congenital heart disease -- Cardiac source of embolism -- Assessment of diastolic function -- Cardiac involvement by systemic diseases -- Interventional procedures.
  • Development and developmental disorders -- Neuroembryology -- Regional anatomy and related syndromes -- Peripheral nerves -- Plexuses -- Nerve roots and spinal nerves -- Spinal cord -- Brainstem -- Cranial nerves -- Cerebellum -- Thalamus -- Hypothalamus -- Basal ganglia -- Limbic system -- Cerebral cortex -- System-based anatomy and differential diagnosis -- Somatosensory system -- Visual system -- Auditory system -- Ocular motor system -- Motor system -- Autonomic nervous system -- Consciousness -- Fluid-system anatomy and function -- Vascular system -- Cerebrospinal fluid.
  • "This eagerly awaited book offers a unique, comprehensive scientific study of the anatomy of the organ of female sexual pleasure. The authors use macroscopic and microscopic research to guide the reader from the glans, the visible part of the clitoris, where they explore the impressive sensory corpuscles, to the hidden roots of the bulbo-clitoral organ. They show its complexity, its exact location within the external genitalia and its intimate relationship with the urethro-vaginal pyramid. They also remind us that throughout history there has been a failure to understand this organ, and explain that this misunderstanding remains the cause of persistent excisions, criminal mutilating practices that have not yet been eradicated. Using extensive iconography, they demonstrate throughout this book that the bulbo-clitoral organ is an exceptional natural treasure that every woman possesses and that every man should know well."--Publisher's website.
  • Anatomical imaging 2008, Springer
    Head anatomy of male and female Mongolian gazelle - a striking example of sexual dimorphism / R. Frey ... [et al.] -- Anatomical peculiarities of the vocal tract in felids / G.E. Weissengruber ... [et al.] -- The anatomical foundation for multidisciplinary studies of animal limb function : examples from dinosaur and elephant limb imaging studies / J.R. Hutchinson ... [et al.] -- Locomotion-related femoral trabecular architectures in primates - high resolution computed tomographies and their implications for estimations of locomotor preferences of fossil primates / H. Scherf -- Three-dimensional imaging of the manipulating apparatus in the lesser panda and the giant panda / H. Endo ... [et al.] -- Using CT to peer into the past : 3D visualization of the brain and ear regions of birds, crocodiles, and nonavian dinosaurs / L.M. Witmer ... [et al.] -- Evolutionary morphology of the autonomic cardiac nervous system in non-human primates and humans / T. Kawashima and H. Sasaki.
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  • Anatomy of addiction. 1st ed. 2011, Click LINK above for location/circulation status.
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    The astonishing account of the decades-long cocaine use of Sigmund Freud and William Halsted. The author discusses the physical and emotional damage caused by the constant use of the then-heralded wonder drug, and of how each man ultimately changed the world in spite of it--or because of it.
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  • Existing anatomy ontologies for human, model organisms and plants -- Anatomical ontologies for model organisms : the fungi and animals / Jonathan Bard -- Plant structure ontology (PSO) : a morphological and anatomical ontology of flowering plants / Katica Ilic, ... [et al.] -- Anatomy for clinical terminology / Alan L. Rector -- The foundational model of anatomy ontology / Cornelius Rosse and José L. V. Mejino, Jr. -- Towards a disease ontology / Paul N. Schofield, Björn Rozell, Georgios V. Gkoutos -- Engineering and linking of anatomy ontologies -- Ontology alignment and merging / Patrick Lambrix, He Tan -- COBrA and COBrA-CT : ontology engineering tools / Stuart Aitken, Yin Chen -- XSPAN : a cross-species anatomy network / Albert Burger, Jonathan Bard -- Searching biomedical literature with anatomy ontologies / Thomas Wächter, ... [et al.] -- Anatomy ontologies and spatio-temporal atlases -- Anatomical ontologies : linking names to places in biology / Richard A. Baldock, Albert Burger -- Time in anatomy / Duncan Davidson -- The Edinburgh mouse atlas / Richard Baldock, Duncan Davidson -- The smart atlas : spatial and semantic strategies for multiscale integration of brain data / Maryann E. Martone, ... [et al.] -- Anatomy ontologies : modelling principles -- Modelling principles and methodologies : relations in anatomical ontologies / Fabian Neuhaus, Barry Smith -- Modeling principles and methodologies : spatial representation and reasoning / Thomas Bittner, ... [et al.] -- CARO : the common anatomy reference ontology / Melissa A. Haendel, ... [et al.]
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  • Ancestors and antiretrovirals 2013, Click LINK above for location/circulation status.
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    "In the years since the end of apartheid, South Africans have enjoyed a progressive constitution, considerable access to social services for the poor and sick, and a booming economy that has made their nation into one of the wealthiest on the continent. At the same time, South Africa experiences extremely unequal income distribution, and its citizens suffer the highest prevalence of HIV in the world. As Archbishop Desmond Tutu has noted, "AIDS is South Africa's new apartheid." In Ancestors and Antiretrovirals, Claire Laurier Decoteau backs up Tutu's assertion with powerful arguments about how this came to pass. Decoteau traces the historical shifts in health policy after apartheid and describes their effects, detailing, in particular, the changing relationship between biomedical and indigenous health care, both at the national and the local level. Decoteau tells this story from the perspective of those living with and dying from AIDS in Johannesburg's squatter camps. At the same time, she exposes the complex and often contradictory ways that the South African government has failed to balance the demands of neoliberal capital with the considerable health needs of its population." -- Publisher's description.
  • Ancient medicine. 2nd ed. SU Catalog (SearchWorks), Click LINK above for location/circulation status.
    Print Material
    1. Sources and scope -- 2. Patterns of disease -- 3. Before Hippocrates -- 4. Hippocrates, the Hippocratic Corpus and the defining of medicine -- 5. Hippocratic theories -- 6. Hippocratic practices -- 7. Religion and medicine in fifth- and fourth-century Greece -- 8. From Plato to Praxagoras -- 9. Alexandria, anatomy and experimentation -- 10. Hellenistic medicine -- 11. Rome and the transplantation of Greek medicine -- 12. The Consequences of empire: pharmacology, surgery and the Roman army -- 13. The Rise of Methodism -- 14. Humoral alternatives -- 15. The Life and career of Galen -- 16. Galenic medicine -- 17. All sorts and conditions of (mainly) men -- 18. Medicine and the religions of the Roman Empire -- 19. Medicine in the Later Roman Empire -- 20. Conclusion.
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  • Androgen action and modulation of prostate and prostate cancer growth : an historical perspective / Shutsung Liao ... [et al.] -- Clinical progression to castration-recurrent prostate cancer / Mark Pomerantz and Philip Kantoff -- Differential roles of androgen receptor in prostate development and cancer progression / Shuyuan Yeh ... [et al.] -- Imaging androgen receptor function in vivo / Michael Carey and Lily Wu -- Increased expression of genes converting adrenal androgens to testosterone in castration-recurrent prostate cancer / Steven P. Balk -- Androgen-metabolic genes in prostate cancer predisposition and progression / Juergen K.V. Reichardt and Ann W. Hsing -- Effect of steroid 5[alpha]-reductase inhibitors on markers of tumor regression and proliferation in prostate cancer / Lynn N. Thomas and Roger S. Rittmaster -- 5[alpha]-reductase isozymes in castration-recurrent prostate cancer / Mark A. Titus and James L. Mohler -- Improving intermittent androgen-deprivation therapy : OFF cycle and the role of steroid 5[alpha]-reductase inhibitors / Shubham Gupta, Daniel Shevrin, and Zhou Wang -- Insights from AR gene mutations / Grant Buchanan ... [et al.] -- Functional motifs of the androgen receptor / Elizabeth M. Wilson -- The role of the androgen receptor polyglutamine tract in prostate cancer : in mice and men / Diane M. Robbins -- The androgen receptor coactivator-binding interface / Eva Estébanez-Perpiñá and Robert J. Fletterick -- Co-regulators and the regulation of androgen receptor action in prostate cancer / Irina U. Agoulnik and Nancy L. Weigel -- Androgen receptor coregulators and their role in prostate cancer / Latif A. Wafa, Robert Snoek, and Paul S. Rennie -- Interaction of the androgen receptor ligand-binding domain with the n-terminal domain and with coactivators / Jan Trapman -- Multitasking and interplay between the androgen receptor domains / F.Claessens, T. Tanner, and A. Haelens -- Chromatin remodeling and androgen receptor-mediated transcription / Li Jia ... [et al.] -- Ligand-independent androgen receptor activity / Scott M. Dehm and Donald J. Tindall -- Role of IL-6 in regulating the androgen receptor / Zoran Culig and Alfred Hobisch -- The role of cyclic AMP in regulating the androgen receptor / Marianne D. Sadar --Cellular and molecular signatures of androgen ablation of prostate cancer / Clifford G. Tepper and Hsing-Jien Kung -- Tissue levels of androgens in castration-recurrent prostate cancer / James L. Mohler and Mark A. Titus -- Unique effects of wnt signaling on prostate cancer cells : modulation of the androgen signaling pathway by interactions of the androgen receptor gene and protein with key components of the canonical wnt signaling pathway / Matthew J. Tanner ... [et al.] -- The role of foxa proteins in the regulation of androgen receptor activity / David J. DeGraff ... [et al.] -- Androgen receptor as a licensing factor for DNA replication / Donald J. Vander Griend and John T. Isaacs -- Androgen-regulated genes in the prostate / Nigel Clegg and Peter S. Nelson -- Mapping the androgen receptor cistrome / Qianben Wang and Myles Brown -- Differential regulation of clusterin isoforms by the androgen receptor Tanya K. Day, Colleen C. Nelson, and Martin E. Gleave -- Androgen regulation of prostate cancer gene fusions / Rou Wang, Scott A. Tomlins, and Arul M. Chinnaiyan -- Androgens and the lipogenic switch in prostate cancer / Johannes V. Swinnen ... [et al.] -- Molecular biology of novel targets identified through study of castration-recurrent prostate cancer / Philip A. Watson and Charles L. Sawyers -- Selenium and androgen receptor in prostate cancer / Nagalakshmi Nadiminty and Allen C. Gao.
  • 1. The Institute of Medicine White Paper on Testosterone: Current Perspective / Craig F. Donatucci -- 2. The Laboratory Diagnosis of Testosterone Deficiency / Akanksha Mehta and Darius A. Paduch -- 3. The Clinical Diagnosis of Androgen Deficiency / Gregory C. Mitchell, Ege Can Serefoglu, and Wayne J.G. Hellstrom -- 4. The Use of Patient Reported Outcome Questionnaires in the Diagnosis of Androgen Deficiency / Gregory J. Lowe, George C. Bailey, and Tracey L. Krupski -- 5. Testosterone and Its Association with Metabolic and Cardiovascular Disease / Giovanni Corona, Giulia Rastrelli, and Mario Maggi -- 6. The Role of Androgens in Prostate Cancer / Frances Alba, Claudio A. Romero, and Run Wang -- 7. Androgen Deficiency in the Adolescent Male / Erin R. McNamara and Sherry S. Ross -- 8. Effects of Androgen Deficiency and Replacement on Male Fertility / Andrew C. Kramer -- 9. HIV and Testosterone in Men / Gina Cambareri, Jane Ashby, David Goldmeier, and Hossein Sadeghi-Nejad -- 10. Treatment Options for Testosterone Replacement Therapy / Mohit Khera -- 11. Alternate Therapies for Testosterone Replacement / Ege Can Serefoglu, Ahmet Gokce, Wayne J.G. Hellstrom, and André T. Guay.
  • A brief history of androgen excess / Ricardo Azziz -- Ovarian and adrenal androgen biosynthesis and metabolism / Walter L. Miller, David H. Geller, and Mitchell Rosen -- Androgens throughout the life of women / C. Richard Parker, Jr. -- Physiological effects of androgens in women / T. Keta Hodgson and Glenn D. Braunstein -- Androgen measurements: methods, interpretation, and limitations / Frank Z. Stanczyk -- Androgen-secreting adrenal and ovarian neoplasms / Michel Pugeat ... [et al.] -- Cushing's syndrome, acromegaly, and androgen excess / Anne-Céline Reyss and Didier Dewailly -- The nonclassic adrenal hyperplasias / Didier Dewailly and Ricardo Azziz -- Pregnancy-related androgen excess / Howard D. McClamrock -- Drug-induced hyperandrogenism / Barbara Neraud and Didier Dewailly -- Severe insulin-resistant hyperandrogenic syndromes / David E. Moller, Antonio Vidal-Puig, and Ricardo Azziz -- Idiopathic hirutism / Enrico Carmina -- Definition and epidemiology of the polycystic ovary syndrome / Ricardo Azziz -- Clinical features of the polycystic ovary syndrome / Walter Futterweit, Evanthia Diamanti-Kandarakis, and Ricardo Azziz -- Biochemical features of the polycystic ovary syndrome / Adam H. Balen -- Ovarian histology, morphology, and ultrasonography in the polycystic ovary syndrome / Sophie Jonard ... [et al.] --Hypothalamic-pituitary-gonadtrophic dysfunction in the polycystic ovary syndrome / R. Jeffrey Chang and Rinku V. Mehta -- Ovarian steroidogenic abnormalities in the polycystic ovary syndrome / Denis A. Magoffin -- Hypothalamic-pituitary-adrenal dysfunction in the polycystic ovary syndrome / Bulent O. Yildiz, Enrico Carmina, and Ricardo Azziz -- The genetic basis of the polycystic ovary syndrome / Mark O. Goodarzi -- Pediatric hyperandrogenism and the polycystic ovary syndrome in adolescence / Kathleen M. Hoeger -- Environmental factors in the polycystic ovary syndrome / Marie-France Hivert and Jean-Patrice Baillargeon -- Animal models and fetal programming of the polycystic ovary syndrome / David H. Abbott ... [et al.] -- Insulin resistance and hyperinsulinism in the polycystic ovary syndrome / Paulina A. Essah and John E. Nestler -- The endocrine impact of obesity and body habitus in the polycystic ovary syndrome / Renato Pasquali and Alessandra Gambineri -- Molecular mechanisms of insulin resistance in the polycystic ovary syndrome / Theodore P. Ciaraldi -- Menstrual dysfunction and endometrial neoplasia in the polycystic ovary syndrome / Abdulkadir Wagley and Paul Hardiman -- Beta-cell dysfunction, glucose intolerance, and diabetes in the polycystic ovary syndrome / David A. Ehrmann -- Hypertension and cardiovascular and lipoprotein abnormalities in the polycystic ovary syndrome / Francesco Orio and Stefano Palomba --Reproductive and obstetrical consequences of the polycystic ovary syndrome / Mary C. Johnson and Richard S. Legro -- Psychosocial and quality-of-life consequences of androgen excess and the polycystic ovary syndrome / Onno E. Janssen, Susanne Hahn, and Sigrid Elsenbruch -- Overview of long-term morbidity and economic cost of the polycystic ovary syndrome / Ricardo Azziz -- Clinical and hormonal evaluation of androgen excess / Ricardo Azziz -- Ovarian suppression and treatment of hirsutism / Paolo Moghetti -- Polycystic ovary syndrome and ovulation induction / Bulent O. Yildiz and Ricardo Azziz -- In vitro fertilization for the polycystic ovary syndrome / Hanadi Ba-Akdah ... [et al.] -- Surgical management of the polycystic ovary syndrome / Adam H. Balen -- Use of insulin sensitizers in the polycystic ovary syndrome / Kai I. Cheang and John E. Nestler -- Weight reduction and lifestyle modification in the treatment of androgen excess / Manny Noakes ... [et al.].
  • Recent studies demonstrated a key role of the androgen receptor in the development of castration-recurrent or -resistant prostate cancer (CRPC), which is deadly and in urgent need of more effective therapies. Understanding the functions of androgen-responsive genes and their regulation and deregulation in prostate cancer progression may lead to new approaches to prevent and treat prostate cancer patients. This book provides an up-to-date review of the overall androgen-responsive gene expression program and the regulation, function, and clinical relevance of both protein coding and non-coding androgen-responsive genes. Experts in the field of androgen action and prostate cancer research discussed the importance of DNA elements, chromatin structure, cellular signaling, and cell-cell interactions in the regulation of androgen-responsive genes in the context of prostate cancer progression, including the development of CRPC. This book is intended for individuals interested in cancer endocrinology and medical and healthcare professionals involved in prostate cancer research.
  • Andrology. 3rd ed. 2010, Springer
    1. Scope and goals of andrology / Eberhard Nieschlag -- 2. Physiology of testicular function / Gerhard F. Weinbauer ... [et al.] -- 3. Physiology of sperm maturation and fertilization / Trevor G. Cooper and Ching-Hei Yeung -- 4. Classification of andrological disorders / Frank Tüttelmann and Eberhard Nieschlag -- 5. Anamnesis and physical examination / Eberhard Nieschlag and Hermann M. Behre -- 6. Imaging diagnostics / Hermann M. Behre and Michael Zitzmann -- 7. Endocrine laboratory diagnosis / Manuela Simoni and Eberhard Nieschlag -- 8. Cytogenetic and molecular genetic investigations / Manuela Simoni and Peter Wieacker -- 9. Semen analysis / Trevor G. Cooper -- 10. Sperm quality and function tests / Ching-Hei Yeung and Trevor G. Cooper -- 11. Testicular biopsy and histology / Martin Bergmann and Sabine Kliesch -- 12. Diseases of the hypothalamus and the pituitary gland / Hermann M. Behre ... [et al.] -- 13. Disorders at the testicular level / Eberhard Nieschlag ... [et al.] -- 14. The aging male and late-onset hypogonadism / Claus Rolf, Michael Zitzmann, and Eberhard Nieschlag -- 15. Diseases of the seminal ducts / Hermann M. Behre ... [et al.] -- 16. Disorders of erection, cohabitation, and ejaculation / Hermann van Ahlen and Sabine Kliesch -- 17. Disorders of androgen target organs / Peter F. Wieacker, Hermann M. Behre, and Eberhard Nieschlag --18. Testicular dysfunction in systemic diseases / Gideon A. Sartorius and David J. Handelsman -- 19. Environmental influences on male reproductive health / Martin H. Brinkworth and David J. Handelsman -- 20. Gynecology relevant to andrology / Ulrich A. Knuth -- 21. Testosterone therapy / Eberhard Nieschlag and Hermann M. Behre -- 22. Empirical therapies for idiopathic male infertility / Eberhard Nieschlag and Axel Kamischke -- 23. Assisted reproduction / Christian De Geyter, Maria De Geyter, and Hermann M. Behre -- 24. Cryopreservation of human spermatozoa / Sabine Kliesch ... [et al.] -- 25. Psychology of fertility disorders / Regina Oberpenning, Fritz A. Muthny, and Frank Oberpenning -- 26. Sexual medicine and andrology / Klaus M. Beier -- 27. Male contribution to contraception / Eberhard Nieschlag -- 28. Vasectomy and refertilization / Udo H. Engelmann and Oliver Gralla -- 29. Approaches to hormonal male contraception / Eberhard Nieschlag and Hermann M. Behre -- 30. Pharmacological approaches to male contraception / Trevor G. Cooper and Ching-Hei Yeung -- 31. Ethical aspects of reproductive medicine / Klaus Demmer.
  • Anemia in the elderly 2007, Springer
  • Applied anatomy of the aorta -- Acute aortic syndrome -- Preoperative cardiac evaluation before aortic surgery -- Role of echocardiography in aortic surgery -- Operative techniques in surgery of the proximal thoracic aorta and aortic arch -- Anesthesia for surgery of the ascending aorta and aortic arch -- Deep hypothermic circulatory arrest -- Cerebral monitoring during aortic surgery -- Understanding open repair of the descending thoracic and thoracoabdominal aorta -- Anesthesia for descending aortic surgery -- Spinal cord protection strategies -- Understanding endovascular aortic surgery: Endovascular repair of aortic aneurysmal disease -- Anesthesia for endovascular aortic surgery -- Anesthesia for open abdominal aortic aneurysm repair -- Renal protection strategies -- Comprehansive management of patients with traumatic aortic injury -- Anesthesia for adult congenital aortic surgery -- Atherosclerosis of the aorta and prevention of neurological dysfunction after cardiac surgery -- Postoperative care after aortic surgery.
  • Eye, ear, nose, and throat diseases -- Cardiac diseases -- Congenital heart disease -- Respiratory diseases -- Liver diseases -- Obesity and nutrition disorders -- Renal diseases -- Neurological diseases -- Muscle diseases -- Skin and bone disorders -- Hematologic diseases -- Infectious diseases and biologic weapons -- Diseases of the endocrine system -- Mitochondrial Disease -- Psychiatric and behavioral disorders -- Mineral, vitamin, and herbal supplements -- Trauma and acute care -- Burns -- Pregnancy and obstetric complications -- Geriatric patient -- Pediatric patient.
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    Myocardial physiology and the interpretation of cardiac catheterization data -- Monitoring -- Anesthesia for myocardial revascularization -- Anesthesia for valvular heart disease -- Congenital heart disease -- Anesthesia for heart, heart-lung, and lung transplantation -- Pericardial disease -- Anesthesia for surgery of the thoracic aorta -- Management of cardiopulmonary bypass -- Mechanical circulatory support -- Myocardial preservation during cardiopulmonary bypass -- Special considerations during cardiac surgery.
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  • This is an up-to-date clinical reference on anesthesia for urological surgery. Advances in urological procedures, the advent of treatment of patients with strong anticoagulant and antiplatelet medications, and the demographics of urology patients (many of whom are young or elderly) present challenges for the anesthesiologist and have necessitated changes in anesthesia practice. Urological anesthesia is not recognized as a subspecialty, and this book, which reflects the expertise of clinicians and researchers from around the United States and Europe, is written for the majority of anesthesiologists and nurse anesthetists who will provide anesthesia for these patients. The book includes coverage of these topics: Renal physiology and pharmacology Urologic anesthesia in all age groups, and in both the operating room and outpatient setting Special considerations in the pregnant patient and in renal transplantation Anesthesia for robotic surgery of the prostate In older patients, problems arising from co-morbidities and the risk of drug interactions Appropriate pain management in inpatient and outpatient settings The unique challenges of positioning the patient Medico-legal considerations, including analyses from the closed claims study
  • Propofol ketamine with bispectral index (BIS) monitoring / Barry L. Friedberg -- Preoperative instructions, intraoperative environment / Barry L. Friedberg -- Level-of-consciousness monitoring / Scott D. Kelley -- The dissociative effect and preemptive analgesia / Barry L. Friedberg -- Special needs of cosmetic dental patients / James A. Snyder -- Propofol Ketamine in the UK, Propofol Ketamine beyond cosmetic surgery / Chris Pollock -- Propofol Ketamine beyond cosmetic surgery : implications for military medicine and mass-casualty anesthesia / Joel W. McMasters -- Lidocaine use and toxicity in cosmetic surgery / Adam Frederic Dorin -- Local anesthetic blocks in head and neck surgery / Joseph Niamtu -- Local anesthetics and surgical considerations for body contouring / Roger Wade Pielet -- Intravenous anesthesia for cosmetic surgery / David Barinholtz -- Regional anesthesia for cosmetic surgery / Holly Evans and Susan M. Steele -- General inhalation anesthesia for cosmetic surgery / Meena Desai -- Preanesthetic assessment of the cosmetic surgery patient / Norman Levin -- Psychological aspects of cosmetic surgery / David B. Sarwer, Canice E. Crerand, and Lauren M. Gibbons -- The business of the office-based anesthesia for cosmetic surgery / Marc E. Koch -- The politics of office-based anesthesia / David Barinholtz -- Staying out of trouble : the medicolegal perspective / Ann Lofsky.
  • Anesthesia informatics 2008, Springer
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